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1

Conceicao, Viviane. "Genome-Wide Host Gene Expression Analysis Before and After the Initiation of Highly Active Antiretroviral Therapy And Natural Control of HIV in Therapy Naïve HIV+ Non-Progressors." Thesis, The University of Sydney, 2013. http://hdl.handle.net/2123/9384.

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Since its discovery 25 years ago, the HIV virus has infected more than 34 million people in the world; the infection caused by this virus has led the world to its most terrible pandemic, and the greatest global health crises of our times. The host-virus interaction and natural history of the disease are influenced by the distinctive interface the virus has with each infected individual. The infection with HIV-1 is characterized by the destruction of CD4+ T-cells during the typical course of the infection, but HIV has the arsenal to infect practically all the major blood leukocytes. Taken from
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2

van, Bockel David John Clinical School St Vincent's Hospital Faculty of Medicine UNSW. "Qualitative analysis of T-cell repertoire for relevance to non-progressive HIV infection." Publisher:University of New South Wales. Clinical School - St Vincent's Hospital, 2008. http://handle.unsw.edu.au/1959.4/41304.

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Cytotoxic T-lymphocytes are important for the control of viral replication during HIV infection, however the magnitude and breadth of HIV-specific CD8+ T-cell response does not correlate well. The purpose for this study was the examination of the HLA-B*2705-specific CD8+ T-cell response to the KRWIILGLNK (KK10) epitope as a definitive model of immune control over HIV replication. The breadth of the T-cell receptor (TCR) repertoire was determined for an association between the qualitative nature of this response and immune escape and therefore, disease progression. Methodology was developed and
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3

Bignami, F. "L'ESPOSIZIONE AD HIV-1 INFLUENZA LA RISPOSTA IMMUNITARIA CD4-MEDIATA ALTERANDO IL PROFILO D'ESPRESSIONE DEI MICRORNA CELLULARI." Doctoral thesis, Università degli Studi di Milano, 2010. http://hdl.handle.net/2434/150033.

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MicroRNAs (miRNAs) are small single-strand non-coding RNAs that repress gene expression by inhibiting translation. MiRNAs are known to inhibit HIV-1 expression interfering with viral mRNAs. In order to better understand how HIV-related alterations in cellular physiology and immunologic control function, 3 classes of patients (éLTNP, Naive and multiply exposed to HIV-1 uninfected subjects, named MEU) were enrolled, from whom blood CD4+ cells were purified. In this cellular subtype the expression levels of 377 miRNAs were analyzed by TaqMan real-time PCR-based arrays. Only miRNAs expressed in 70
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4

Parnicza, Justin W. "WV LTAP PMS integrating GIS with PMS software /." Morgantown, W. Va. : [West Virginia University Libraries], 2010. http://hdl.handle.net/10450/10848.

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Thesis (M.S.)--West Virginia University, 2010.<br>Title from document title page. Document formatted into pages; contains ix, 97 p. : ill. (some col.), col. maps. Includes abstract. Includes bibliographical references (p. 51).
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5

Arend, Marcos Osmar. "Lente Toroidal de Plasma (LTP)." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2016. http://tede2.pucrs.br/tede2/handle/tede/7003.

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Submitted by Setor de Tratamento da Informa??o - BC/PUCRS (tede2@pucrs.br) on 2016-10-18T19:14:49Z No. of bitstreams: 1 DIS_MARCOS_OSMAR_AREND_COMPLETO.pdf: 1612492 bytes, checksum: 3f2e39f9c93bb63e715df6eb4a8a4d09 (MD5)<br>Made available in DSpace on 2016-10-18T19:14:49Z (GMT). No. of bitstreams: 1 DIS_MARCOS_OSMAR_AREND_COMPLETO.pdf: 1612492 bytes, checksum: 3f2e39f9c93bb63e715df6eb4a8a4d09 (MD5) Previous issue date: 2016-08-26<br>This paper proposes the use of plasma lenses to replace the classical solid dielectric lens for focusing the electromagnetic wave, with application in theaters o
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6

Lack, Jeremy David. "The solution structure and surface properties of TB3 of LTBP-1." Thesis, University of Oxford, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249190.

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7

Steer, Ruth. "Investigations of the extracellular deposition of latent TGF-beta binding protein-1 (LTBP-1)." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/investigations-of-the-extracellular-deposition-of-latent-tgfbeta-binding-protein1-ltbp1(41e0ee4f-5030-4333-8a52-e0d21d1fc649).html.

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LTBP-1 is a large extracellular glycoprotein that is a component of the large latent TGF-β complex. The extracellular sequestration of latent TGF-β in the extracellular matrix (ECM) is fundamental to the regulation of TGF-β bioavailability and activity. LTBP-1 is described to contribute to the regulation of TGF-β bioavailability through mediating the extracellular sequestration of newly secreted latent TGF-β with fibrillin microfibrils in the ECM. However it is not well understood how LTBP-1, and thus latent TGF-β, becomes deposited into the ECM. Previous work by our group suggested that LTBP-
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8

Evans, Gary Lee. "The induction of long-term potentiation attenuates kainic acid-induced excitotoxicity." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/777.

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The activation of N-methyl-D-aspartate glutamate receptors (NMDARs) is required for the long term potentiation (LTP) and long term depression (LTD) of excitatory synaptic transmission at hippocampal CA1 synapses, and plays an important role in learning and memory. In addition, it is accepted that the over-activation of NMDARs leads to the neurotoxicity associated with stroke and other neurodegenerative disorders. Thus, the NMDAR provides a logical starting point to investigate a possible relationship between synaptic plasticity and the cell-signalling pathways which ultimately determine neur
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9

Yan, Yi. "The role of Akt in AMPA receptor insertion and LTP." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/31741.

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It has been widely accepted that long-term potentiation (LTP) in the hippocampal CA1 region mostly results from increased insertion of post-synaptic α-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid receptors (AMPARs). The previous study in our lab has shown that activation of phosphatidylinositol 3-kinase (PI3K) by selective stimulation of synaptic N-methyl-D-aspartate receptors (NMDARs) is required for the increased cell surface expression of AMPARs and the consequent LTP. However, the following signaling pathways still remain unknown. In the present study, the involvement of Akt,
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10

Lu, You Ming. "Signaling cascades underlying two different forms of LTP in hippocampus." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0007/NQ41219.pdf.

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11

Barrag��n, Guti��rrez Jos�� Eduardo. "An��lisis de factibilidad de una empresa dedicada al dise��o de experiencias." Thesis, Universidad de las Am��ricas Puebla, 2012. http://catarina.udlap.mx/u_dl_a/tales/documentos/ltn/barragan_g_je/.

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12

del, Moral S��nchez Jos�� Luis, and Salinas Diego Armando Torres. "Desarrollo de Estrategias para Empresas Basadas en Sistemas de Simulac����n Din��mica." Thesis, Universidad de las Am��ricas Puebla, 2011. http://catarina.udlap.mx/u_dl_a/tales/documentos/ltn/del_m_jl/.

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13

De, La Rosa Morales Rafael Alfredo. "Evaluaci��n del impacto de los portales web de gobierno estatal en M��xico." Thesis, Universidad de las Am��ricas Puebla, 2012. http://catarina.udlap.mx/u_dl_a/tales/documentos/ltn/de_l_ra/.

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14

Jain, Saurabh. "LTCP-RC: RTT compensation technique to scale high-speed protocol in high RTT links." Texas A&M University, 2005. http://hdl.handle.net/1969.1/2528.

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In this thesis, we propose a new protocol named Layered TCP with RTT Compensation (LTCP-RC, for short). LTCP-RC is a simple modification to the congestion window response of the high-speed protocol, Layered TCP (LTCP). In networks characterized by large link delays and high RTTs, LTCP-RC makes the LTCP protocol more scalable. Ack-clocked schemes, similar to TCP, suffer performance problems like long convergence time and throughput degradation, when RTT experienced by the flow increases. Also, when flows with different RTTs compete, the problem of unfairness among competing flows becomes worse
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15

Langlais, Valentin. "Contrôle de l'activité des récepteurs NMDA par la D-sérine : rôle des récepteurs astrocytaires EphB3 et CB1." Thesis, Bordeaux, 2016. http://www.theses.fr/2016BORD0211/document.

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Les astrocytes sont des partenaires clés des neurones. Dans l’hippocampe, et tout particulièrement au niveau des synapses CA3-CA1, en libérant la D-sérine, ces cellules gliales régulent l’activité des récepteurs glutamatergiques de type N-methyl-D-aspartate (NMDA) et de ce fait la mémoire synaptique, aussi connue sous le nom de plasticité synaptique à long terme. Cependant, le signal synaptique à l’origine de la libération de la D-sérine par les astrocytes reste à ce jour méconnu. De par des données rapportées dans la littérature nous nous sommes tout particulièrement intéressés aux récepteurs
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16

Esteves, Ingrid de Miranda. "Caracterização das alterações na via hipocampo-córtex pré-frontal medial em modelo farmacológico da doença de Alzheimer." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/17/17140/tde-26082016-110343/.

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Severas altera¸c~oes no metabolismo energ´etico, no consumo de glicose e na sinaliza¸c~ao de insulina cerebral est~ao presentes na doen¸ca de Alzheimer (DA). O modelo animal da DA obtido pela administra¸c~ao intracerebroventricular de estreptozotocina (STZ-icv) em ratos induz um estado de resist^encia `a insulina no c´erebro associado `a disfun¸c~oes colin´ergicas e a d´eficits cognitivos, tornando-o um dos poucos modelos experimentais da forma espor´adica da DA. Este trabalho tem como objetivo caracterizar, neste modelo, as disfun¸c~oes sin´apticas na via hipocampo - c´ortex pr´e-frontal medi
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17

Cho, Taesup. "Neural stem cell transplantation : neuroprotection and LTP-induced facilitation of neurogenesis." Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/36960.

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Transplantation of neural progenitor cells (NPC) constitutes a putative therapeutic maneuver for use in treatment of neurodegenerative diseases. At present, effects of NPC transplantation in the Alzheimer’s disease (AD) brain are largely unknown and a primary objective of this work is to demonstrate possible efficacy of NPC administration in an AD animal model. The benefits of transplantation could involve a spectrum of effects including replacement of endogenous neurons, conferring neuroprotection with enhancement of neurotrophic factors, and diminishing levels of neurotoxic agents. Additiona
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18

Romberg, Carola. "Hippocampal LTP and spatial learning in glutamate receptor subunit-deficient mice." Thesis, University of Oxford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.442569.

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19

Hashimoto, Kenji. "Occurrence of dentate granule cell LTP without proximal dendritic Ca2+ increase." Kyoto University, 2004. http://hdl.handle.net/2433/147498.

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20

De, Pasquale Roberto. "Visual discrimination learning and LTP-like changes in primary visual cortex." Doctoral thesis, Scuola Normale Superiore, 2009. http://hdl.handle.net/11384/85939.

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21

Svensson, Markus. "Modeling Pavement Performance based on Data from the Swedish LTPP Database : Predicting Cracking and Rutting." Licentiate thesis, KTH, Väg- och banteknik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-119863.

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The roads in our society are in a state of constant degradation. The reasons for this are many, and therefore constructed to have a certain lifetime before being reconstructed. To minimize the cost of maintaining the important transport road network high quality prediction models are needed. This report presents new models for flexible pavement structures for initiation and propagation of fatigue cracks in the bound layers and rutting for the whole structure. The models are based on observations from the Swedish Long Term Pavement Performance (LTPP) database. The intention is to use them for p
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22

Filosa, Alessandro. "Neuron-glia communication via EphA4-ephrinA3 modulates LTP through glial glutamate transport." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-116043.

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23

Liotta, Agustin [Verfasser]. "Impact of disinhibition and neuromodulation in hippocampal oscillations and LTP / Agustin Liotta." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2012. http://d-nb.info/1026991412/34.

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24

Richards, David Andrew. "On the role of arachidoic acid in long term potentation." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286684.

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25

Phillips, Keith Geoffrey. "Role of nitric oxide and somatic action potentials in a GluR1 independent LTP." Thesis, Cardiff University, 2010. http://orca.cf.ac.uk/55048/.

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Studies in GluRl knockout mice have shown that neocortical LTP consist of both pre- and post-synaptic components that rely on nitric oxide and GluRl respectively (Hardingham and Fox, 2006). Given that GluRl knockout also show hippocampal LTP (Hoffmann et al., 2002) I hypothesised that the residual LTP might depend on nitric oxide. I have found that hippocampal LTP can be induced in GluRl knockout with purely orthodromic stimuli in mature mice (>8weeks) and that a theta-burst protocol was effective at inducing LTP while 100Hz stimulation was not. I found that only theta-burst stimulation produc
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26

Lefort, Julie. "Role of cerebellar LTP at parallel fiber : Purkinje cell synapses in spatial navigation." Thesis, Paris 6, 2014. http://www.theses.fr/2014PA066151/document.

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La navigation spatiale peut être subdivisée en deux processus: la construction d’une représentation mentale de l’espace à partir de l’exploration de l’environnement d'une part, et l’utilisation de cette représentation de façon à produire le trajet le plus adapté pour rejoindre le lieu souhaité d'autre part. Lors de l’exploration de l’environnement, des informations externes et des informations de mouvement propre (i.e. vestibulaires et proprioceptives) sont combinées pour former la carte cognitive. Depuis longtemps des études suggèrent que le cervelet participe à la navigation spatiale mais so
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27

Aya, Rino. "Regeneration of elastic fibers by three-dimensional culture on a collagen scaffold and the addition of latent TGF-β binding protein 4 to improve elastic matrix deposition". Kyoto University, 2016. http://hdl.handle.net/2433/215396.

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Park, Pojeong. "Calcium-permeable AMPA receptors are required for PKA-dependent LTP at hippocampal CA1 synapses." Thesis, University of Bristol, 2017. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.720854.

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Luckett, Suzanne. "Purification and characterisation of SFTI-1 and LTP from sunflower seeds (Helianthus annuus l.)." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322251.

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Ditto, Andrew J. "DNA-LPEI complexes encapsulated in LTP nanospheres as a non-viral gene therapy vector." University of Akron / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=akron1165596983.

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Ditto, Andrew. "DNA-LPEI complexes encapsulated in LTP nanospheres as a non-viral gene therapy vector." Akron, OH : University of Akron, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=akron1165596983.

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Thesis (M.S.)--University of Akron, Dept. of Biomedical Engineering, 2006.<br>"December, 2006." Title from electronic thesis title page (viewed 12/31/2008) Advisor, Yang Yun; Committee members, Stephanie Lopina, Steven Schmidt; Department Chair, Daniel Sheffer; Dean of the College, George K. Haritos; Dean of the Graduate School, George R. Newkome. Includes bibliographical references.
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32

Alessi, Nicola. "Modifiche al protocollo di trasporto LTP per migliorarne le prestazioni in presenza di perdite elevate." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amslaurea.unibo.it/10314/.

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La presente tesi si pone come obiettivo quello di analizzare il protocollo LTP (in particolare in ION) e proporre dei miglioramenti utili al caso in cui siano presenti perdite elevate. Piu in dettaglio, una prima parte introduttiva motiva l'inefficacia del TCP/IP in ambito interplanetario e introduce l'architettura DTN Bundle Protocol (Cap.1). La tesi prosegue con la descrizione delle specifiche del protocollo LTP (Cap.2), in particolar modo evidenziando come un bundle venga incapsulato in un blocco LTP, come questo sia successivamente diviso in tanti segmenti LTP e come questi vengano success
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33

Barmashenko, Gleb. "Läsionsinduzierte Änderungen der intrazellulären Kalziumkonzentration und der LTP von Neuronen im visuellen Kortex der Ratte." [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=963996037.

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Siemer, Helge. "Über die Beteiligung des Transkriptionsfaktors CREB im Modell der Langzeitpotenzierung (LTP) im Hippocampus der Ratte." [S.l.] : [s.n.], 2001. http://www.diss.fu-berlin.de/2002/303/index.html.

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Kucharczyk, Lilianna Stanislawa Verfasser], and Robert [Akademischer Betreuer] [Bähring. "LTP in conventional and conditional Arc/Arg3.1 KO mice / Lilianna Stanislawa Kucharczyk ; Betreuer: Robert Bähring." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2020. http://d-nb.info/1215292473/34.

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Kucharczyk, Lilianna Stanislawa [Verfasser], and Robert [Akademischer Betreuer] Bähring. "LTP in conventional and conditional Arc/Arg3.1 KO mice / Lilianna Stanislawa Kucharczyk ; Betreuer: Robert Bähring." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2020. http://d-nb.info/1215292473/34.

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Ionescu, Marius Anton. "L' activation éosinophilique dans les lymphomes T cutanés primitifs." Paris 7, 2003. http://www.theses.fr/2003PA077056.

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Kemp, Nicola. "Mechanisms underlying the induction of long-term depression in the CA1 region of the hippocampus." Thesis, University of Bristol, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300704.

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39

Dinger, Katharina [Verfasser]. "Structural and functional analysis of LTBP 4 as a factor of pathogenesis in the development of pulmonary emphysema / Katharina Dinger." Berlin : Freie Universität Berlin, 2017. http://d-nb.info/1129685616/34.

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Sá, Júnior Euridson de. "Mercado secundário de títulos públicos: microestrutura, liquidez e spread de compra e venda para o mercado de LTNs no Brasil." reponame:Repositório Institucional do FGV, 2007. http://hdl.handle.net/10438/1773.

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Made available in DSpace on 2010-04-20T20:56:58Z (GMT). No. of bitstreams: 3 EuridsondeSaJr30082007.pdf.jpg: 13049 bytes, checksum: 4808d05119bc6848b16b52b0b7252ea8 (MD5) EuridsondeSaJr30082007.pdf.txt: 162466 bytes, checksum: 25651c9d22035e3e69d261b34283c1b9 (MD5) EuridsondeSaJr30082007.pdf: 348637 bytes, checksum: 8818c6407c9130859dca82a7ec272a1f (MD5) Previous issue date: 2007-08-30T00:00:00Z<br>This work comprises two parts. First part, it discusses and compares liquidity and market microstructure aspects from government securities in some countries as Brazil, Chile, Mexico, Korea, P
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41

Ximing, LI. "Insights into Delivery of Somatic Calcium Signals to the Nucleus During LTP Revealed by Computational Modeling." Ohio University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou152236301476345.

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42

Moreno, Pérez Nuria. "Fenotipos de alergia alimentaria por sensibilización a proteínas transferidoras de lípidos (LTP) en adultos del área mediterránea." Doctoral thesis, Universitat Autònoma de Barcelona, 2018. http://hdl.handle.net/10803/665226.

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Introducción: Las proteínas transferidoras de lípidos (LTP) son la causa más frecuente de alergia alimentaria y anafilaxia inducida por alimentos en adultos en el área mediterránea. Existe una gran variabilidad en el perfil de reconocimiento molecular frente a estas proteínas y distintos grados de gravedad en su expresión clínica. El objetivo principal de este estudio fue identificar si en la alergia alimentaria por sensibilización a LTP se pueden identificar patrones comunes o clústers en función de parámetros clínicos y del perfil de reconocimiento molecular a alérgenos alimentarios y políni
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43

Brown, Christopher Martin. "Intracellular mechanisms of stress-induced LTP impairment : a signalling pathway triggered by corticosterone in the rat hippocampus." Thesis, University of Bristol, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.715798.

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44

Whitcomb, Daniel. "Alpha-beta1-42 of LTP is mediated by a signaling pathway involving caspase-3, Akt1 GSK-3beta." Thesis, University of Bristol, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.550333.

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Amyloid-f31--42 (Af3) is considered a major mediator of the cognitive impairments that are seen in Alzheimer's disease, the leading form of dementia and a growing world-wide health problem. In vitro, Af3 treatment of hippocampal brain slices impairs long-term potentiation and enhances long- term depression, forms of synaptic plasticity, and as such serve to provide cellular correlates of this action. However, the mechanisms underlying these effects are not fully understood. In this thesis the mechanisms underlying the Aj3-mediated dysregulation of synaptic plasticity are therefore explored. Ex
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45

Müller, Volker. "Entwicklung einer kompetetiven PCR zur Quantifizierung der mRNA von TGF-beta-1 und LTBP-1 in Fettspeicherzellen der Leber von Rattus norvegicus." [S.l.] : [s.n.], 2001. http://archiv.ub.uni-marburg.de/diss/z2001/0306/.

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46

Niggemeyer, Marie Nicola. "Einfluss experimentell modifizierter LTBP-4-Genexpression auf das Expressionsprofil von TGF-[beta]1 [TGF-Beta1], p21 und c-myc in HEK293T Zellen." Berlin mbv, 2007. http://d-nb.info/987696262/04.

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Niggemeyer, Marie Nicola [Verfasser]. "Einfluss experimentell modifizierter LTBP-4-Genexpression auf das Expressionsprofil von TGF-β1, p21 und c-myc in HEK293T Zellen / Marie Nicola Niggemeyer". Berlin : Freie Universität Berlin, 2008. http://d-nb.info/1022697587/34.

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Klusacsek, Katrin [Verfasser]. "Analyse der differentiellen Genexpression der Tumorsuppressorgene TGF-beta1-3 und deren Bindungsproteine LTBP-1, -3 und -4 in caninen Mammatumoren / Katrin Klusacsek." Berlin : Freie Universität Berlin, 2008. http://d-nb.info/1022642650/34.

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Bareiss, Max. "Effectiveness of Intersection Advanced Driver Assistance Systems in Preventing Crashes and Injuries in Left Turn Across Path / Opposite Direction Crashes in the United States." Thesis, Virginia Tech, 2019. http://hdl.handle.net/10919/96570.

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Streszczenie:
Intersection crashes represent one-fifth of all police reported traffic crashes and one-sixth of all fatal crashes in the United States each year. Active safety systems have the potential to reduce crashes and injuries across all crash modes by partially or fully controlling the vehicle in the event that a crash is imminent. The objective of this thesis was to evaluate crash and injury reduction in a future United States fleet equipped with intersection advanced driver assistance systems (I-ADAS). In order to evaluate this, injury risk modeling was performed. The dataset used to evaluate injur
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Schütze, Mareice [Verfasser]. "Malignitätsassoziierte Proteinexpressionsprofile von Derlin-1, TGF-β [TGF-beta], LTBP-4, p27 und RAD51 in metastasierenden Mammatumoren des Hundes / vorgelegt von Mareice Schütze". Berlin : mbv, Mensch-und-Buch-Verl, 2010. http://d-nb.info/1013050827/34.

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