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Gotowe bibliografie tematyczne / Lysosome - related organelles

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Gotowa bibliografia na temat „Lysosome - related organelles”

Autor: Grafiati

Data publikacji: 2 czerwca 2025

Data aktualizacji: 31 lipca 2025

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Artykuły w czasopismach na temat "Lysosome - related organelles"

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Dell'Angelica, Esteban C., Chris Mullins, Steve Caplan, and Juan S. Bonifacino. "Lysosome‐related organelles." FASEB Journal 14, no. 10 (2000): 1265–78. http://dx.doi.org/10.1096/fasebj.14.10.1265.

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DELL'ANGELICA, E. C. "Lysosome-related organelles." FASEB Journal 14, no. 10 (2000): 1265–78. http://dx.doi.org/10.1096/fj.14.10.1265.

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Hermann, Greg J., Lena K. Schroeder, Caroline A. Hieb, et al. "Genetic Analysis of Lysosomal Trafficking inCaenorhabditis elegans." Molecular Biology of the Cell 16, no. 7 (2005): 3273–88. http://dx.doi.org/10.1091/mbc.e05-01-0060.

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The intestinal cells of Caenorhabditis elegans embryos contain prominent, birefringent gut granules that we show are lysosome-related organelles. Gut granules are labeled by lysosomal markers, and their formation is disrupted in embryos depleted of AP-3 subunits, VPS-16, and VPS-41. We define a class of gut granule loss (glo) mutants that are defective in gut granule biogenesis. We show that the glo-1 gene encodes a predicted Rab GTPase that localizes to lysosome-related gut granules in the intestine and that glo-4 encodes a possible GLO-1 guanine nucleotide exchange factor. These and other gl

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Cutler, D. F. "Introduction: lysosome-related organelles." Seminars in Cell & Developmental Biology 13, no. 4 (2002): 261–62. http://dx.doi.org/10.1016/s108495210200054x.

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Santo, Manuela, and Ivan Conte. "Emerging Lysosomal Functions for Photoreceptor Cell Homeostasis and Survival." Cells 11, no. 1 (2021): 60. http://dx.doi.org/10.3390/cells11010060.

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Lysosomes are membrane-bound cell organelles that respond to nutrient changes and are implicated in cell homeostasis and clearance mechanisms, allowing effective adaptation to specific cellular needs. The relevance of the lysosome has been elucidated in a number of different contexts. Of these, the retina represents an interesting scenario to appreciate the various functions of this organelle in both physiological and pathological conditions. Growing evidence suggests a role for lysosome-related mechanisms in retinal degeneration. Abnormal lysosomal activation or inhibition has dramatic conseq

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Watts, Colin. "Lysosomes and lysosome‐related organelles in immune responses." FEBS Open Bio 12, no. 4 (2022): 678–93. http://dx.doi.org/10.1002/2211-5463.13388.

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Luzio, J. P., Y. Hackmann, N. M. G. Dieckmann, and G. M. Griffiths. "The Biogenesis of Lysosomes and Lysosome-Related Organelles." Cold Spring Harbor Perspectives in Biology 6, no. 9 (2014): a016840. http://dx.doi.org/10.1101/cshperspect.a016840.

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Biswas, Suprakash, Tanoy Dutta, Akshay Silswal, Rohit Bhowal, Deepak Chopra, and Apurba L. Koner. "Strategic engineering of alkyl spacer length for a pH-tolerant lysosome marker and dual organelle localization." Chemical Science 12, no. 28 (2021): 9630–44. http://dx.doi.org/10.1039/d1sc00542a.

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A series naphthalimide-based fluorophores were designed by alkyl spacer length engineering to discover a pH-tolerant lysosomal marker. This approach also allows to probe lysosome-related organelles in C. elegans and communication between organelles.

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Newell-Litwa, Karen, Gloria Salazar, Yoland Smith, and Victor Faundez. "Roles of BLOC-1 and Adaptor Protein-3 Complexes in Cargo Sorting to Synaptic Vesicles." Molecular Biology of the Cell 20, no. 5 (2009): 1441–53. http://dx.doi.org/10.1091/mbc.e08-05-0456.

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Neuronal lysosomes and their biogenesis mechanisms are primarily thought to clear metabolites and proteins whose abnormal accumulation leads to neurodegenerative disease pathology. However, it remains unknown whether lysosomal sorting mechanisms regulate the levels of membrane proteins within synaptic vesicles. Using high-resolution deconvolution microscopy, we identified early endosomal compartments where both selected synaptic vesicle and lysosomal membrane proteins coexist with the adaptor protein complex 3 (AP-3) in neuronal cells. From these early endosomes, both synaptic vesicle membrane

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Morgan, Anthony J. "Ca2+ dialogue between acidic vesicles and ER." Biochemical Society Transactions 44, no. 2 (2016): 546–53. http://dx.doi.org/10.1042/bst20150290.

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Extracellular stimuli evoke the synthesis of intracellular second messengers, several of which couple to the release of Ca2+ from Ca2+-storing organelles via activation of cognate organellar Ca2+-channel complexes. The archetype is the inositol 1,4,5-trisphosphate (IP3) and IP3 receptor (IP3R) on the endoplasmic reticulum (ER). A less understood, parallel Ca2+ signalling cascade is that involving the messenger nicotinic acid adenine dinucleotide phosphate (NAADP) that couples to Ca2+ release from acidic Ca2+ stores [e.g. endo-lysosomes, secretory vesicles, lysosome-related organelles (LROs)].

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Rozprawy doktorskie na temat "Lysosome - related organelles"

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Kaur, Jasber. "Targeting of membrane proteins to lysosome-related organelles." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.397316.

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Westmoreland, D. A. "Lysosome-related organelles : an investigation into clinical disorders of endothelial cells and platelets." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1561240/.

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Lysosome-related organelles (LROs) are a heterogeneous group of organelles that have important functions in a number of specialised cell types. LROs, despite their distinct features and morphology, have been grouped together due to the observation that they are simultaneously functionally perturbed by single mutations in a number of genetic disorders, yet as a group they are still poorly understood. Firstly, it was investigated whether the genes that are important for the formation/maturation of other LROs can also affect Weibel-Palade bodies (WPBs) an endothelial LRO that is critical to haemo

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Simões, alves Sabrina. "Roles of the Endosomal Sorting Complexes Required for Transport (ESCRTs) in the biogenesis of Lysosome Related Organelles." Paris 5, 2011. http://www.theses.fr/2011PA05T007.

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Les mélanosomes sont des compartiments membranaires appartenant à la famille des organites apparentés aux lysosomes. Générés par des cellules spécialisées, comme les mélanocytes de la peau, ils synthétisent et stockent un pigment : la mélanine. Leur biogenèse s’organise en une série d’évènements séquentiels au cours desquels la formation d’un organite immature “non pigmenté” précède la génération d’un mélanosome mature “pigmenté”. Pour ce faire, le mélanocyte spécialise une partie de son trafic intracellulaire pour transporter, de manière régulée mélanosomes, les composants structuraux qui le

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Nazarian, Ramin. "Molecular analysis of protein complexes associated with Hermansky-Pudlak syndrome, a genetic disorder of lysosome-related organelles." Diss., Restricted to subscribing institutions, 2007. http://proquest.umi.com/pqdweb?did=1459902921&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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Vanna, R. "CARATTERIZZAZIONE DELL¿ORGANELLO DI NEUROMELANINA DELLA SUBSTANTIA NIGRA UMANA CON APPROCCIO PROTEOMICO." Doctoral thesis, Università degli Studi di Milano, 2012. http://hdl.handle.net/2434/169921.

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Substantia nigra is the most affected brain region in Parkinson's disease. Substantia nigra is characterized by strong pigmentation derived by the presence of neuromelanin (NM), a particular melanic pigment that accumulates during aging in neurons in typical membrane-bounded organelles with high levels of lipids (dolichols). The occurrence of an elevated number of NM organelles in the most vulnerable brain region during Parkinson’s disease is of special interest. It is not clear if NM organelles may interfere with the vulnerability of neurons during aging. Nevertheless, many evidences support

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Jordens, Ingrid. "Transport of lysosome-related organelles /." 2005. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=015446884&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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Ellis, Kathryn Leigh. "Molecular Mechanisms of Notochord Vacuole Formation and Their Role in Zebrafish Development." Diss., 2014. http://hdl.handle.net/10161/8723.

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<p>The notochord plays critical structural and signaling roles during vertebrate development. At the center of the vertebrate notochord is a large fluid-filled organelle, the notochord vacuole. While these highly conserved intracellular structures have been described for decades, little is known about the molecular mechanisms involved in their biogenesis and maintenance. Here we show that zebrafish notochord vacuoles are specialized lysosome-related organelles whose formation and maintenance requires late endosomal trafficking regulated by the vacuole-specific Rab32a, and H+-ATPase-dependent a

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Singh, Suman K., R. Kurfurst, C. Nizard, S. Schnebert, E. Perrier, and Desmond J. Tobin. "Melanin transfer in human skin cells is mediated by filopodia--a model for homotypic and heterotypic lysosome-related organelle transfer." 2010. http://hdl.handle.net/10454/6193.

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Transfer of the melanocyte-specific and lysosome-related organelle, the melanosome, from melanocytes to keratinocytes is crucial for the protection of the skin against harmful ultraviolet radiation (UVR)--our main physiological cutaneous stressor. However, this commonplace event remains a most enigmatic process despite several early hypotheses. Recently, we and others have proposed a role for filopodia in melanin transfer, although conclusive experimental proof remained elusive. Using known filopodial markers (MyoX/Cdc42) and the filopodial disrupter, low-dose cytochalasin-B, we demonstrate he

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Części książek na temat "Lysosome - related organelles"

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Mantegazza, Adriana R., and Michael S. Marks. "Lysosome-Related Organelles: Modifications of the Lysosome Paradigm." In Lysosomes: Biology, Diseases, and Therapeutics. John Wiley & Sons, Inc., 2016. http://dx.doi.org/10.1002/9781118978320.ch12.

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Hurbain, Ilse, Maryse Romao, Ptissam Bergam, Xavier Heiligenstein, and Graça Raposo. "Analyzing Lysosome-Related Organelles by Electron Microscopy." In Methods in Molecular Biology. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-6934-0_4.

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Fukuda, M. "Lysosome-Related Organelles." In Encyclopedia of Cell Biology. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-12-394447-4.20020-5.

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Maruta, Yuto, and Mitsunori Fukuda. "Lysosome-Related Organelles." In Reference Module in Life Sciences. Elsevier, 2022. http://dx.doi.org/10.1016/b978-0-12-821618-7.00121-8.

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Deegan, Patrick B., and Timothy M. Cox. "Lysosomal disease." In Oxford Textbook of Medicine, edited by Timothy M. Cox. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0235.

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The lysosome is a ubiquitous, single membrane-bond intracellular organelle which continuously recycles biological macromolecules: it not only breaks down cell components but has a dynamic role in nutrient and energy sensing that, through regulatory signalling, is critical for homeostasis and metabolic economy of the cell. More than 80 lysosomal diseases caused by single gene defects are known. Biochemical classification identifies (1) sphingolipidoses; (2) mucopolysaccharidoses; (3) glycoproteinoses; (4) glycogenosis, with or without lysosomal debris derived from subcellular organelles due to

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Kaira, Meenakshi, Abhilasha Ahlawat, Vaibhav Walia, and Munish Garg. "Autophagic Dysfunction in Neurodegeneration." In Quality Control of Cellular Protein in Neurodegenerative Disorders. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-1317-0.ch002.

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Autophagy is a normal physiological process characterized by the degradation of complex cellular contents into a simpler one and reutilized them in biosynthetic pathways. Lysosomes are the cell organelle that participates in the process of autophagy. The brain is the most vulnerable organ in most lysosome disorders because neurons are inefficient in removing impaired organelles and waste materials. In the brain, autophagy suppresses the accumulation of ubiquitinated proteins that results in further damage to the neurons responsible for neurodegeneration. Autophagy mediates protective effects i

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Azimi, Fatemeh. "Autophagy and Inflammation in Neuropsychological Disorders." In Autophagy and Inflammation in Neuropsychological Disorders. IGI Global Scientific Publishing, 2025. https://doi.org/10.4018/979-8-3693-5908-2.ch006.

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Vision is a highly complex neural process that begins in the retina and is transmitted to the brain through the optic nerve, relying on the precise function of highly specialized neural and glial cells. It is of great importance for the integrity of vision to maintain the health of these cells. Autophagy, a lysosome-dependent degradation pathway, plays a crucial role in maintaining cellular homeostasis by eliminating misfolded proteins and damaged organelles. Dysregulation of autophagy has been recognized as a pivotal factor in the pathogenesis of multiple neurological-visual diseases, such as

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Allchin, Douglas. "Marxism and Cell Biology." In Sacred Bovines. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190490362.003.0007.

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Few biologists today have likely heard of cell biologist Alex Novikoff (1913–1987) (Figure 3.1). But the fruits of his science are well known. He helped discover the cell organelle called the lysosome. In 1955 he visualized what Christian de Duve had characterized only by chemical means. He documented the first known enzyme of the Golgi body, another cell organelle. He developed ways to stain lysosomes and peroxisomes (also cell organelles) that were critical to identifying them and studying them with the electron microscope. Novikoff also was targeted by the anti-Communist movement in the mid

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Ohkuma, Shoji. "[12] Use of fluorescein isothiocyanate-dextran to measure proton pumping in lysosomes and related organelles." In Biomembranes Part U: Cellular and Subcellular Transport: Eukaryotic (Nonepithelial) Cells. Elsevier, 1989. http://dx.doi.org/10.1016/0076-6879(89)74015-5.

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