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1

Parveen, N., A. A. Khan, S. Baskar, et al. "164 INTRAPERITONEAL TRANSPLANTATION OF HEPATOCYTES EMBEDDED IN THERMOREVERSIBLE GELATION POLYMER (MEBIOL GEL) IN ACUTE LIVER FAILURE RAT MODEL." Journal of Hepatology 48 (January 2008): S71. http://dx.doi.org/10.1016/s0168-8278(08)60166-x.

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Sitalakshmi, G., B. Sudha, H. N. Madhavan, et al. "Ex Vivo Cultivation of Corneal Limbal Epithelial Cells in a Thermoreversible Polymer (Mebiol Gel) and Their Transplantation in Rabbits: An Animal Model." Tissue Engineering Part A 15, no. 2 (2009): 407–15. http://dx.doi.org/10.1089/ten.tea.2008.0041.

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Schröder, Agnes, Ricarda Schöniger, Juliane Oeldemann, et al. "An Evaluation of Different 3D Cultivation Models on Expression Profiles of Human Periodontal Ligament Fibroblasts with Compressive Strain." International Journal of Molecular Sciences 23, no. 4 (2022): 2029. http://dx.doi.org/10.3390/ijms23042029.

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The effects of compressive strain during orthodontic treatment on gene expression profiles of periodontal ligament fibroblasts (PDLFs) have mostly been studied in 2D cell culture. However, cells behave differently in many aspects in 3D culture. Therefore, the effect of pressure application on PDLFs in different 3D structures was investigated. PDLFs were either conventionally seeded or embedded into different 3D structures (spheroids, Mebiol® gel, 3D scaffolds) and exposed to compressive force or incubated without pressure. For one 3D scaffold (POR), we also tested the effect of different compr
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Yolanda, Ovelia, Sekar Dorojati Yuliana, and Yudhi Nugraha. "Effect of Honey, Aloe vera, and MEBO on Collagen Density in Healing Process of Second Degree Burns in Rats." Al-Kauniyah: Jurnal Biologi 14, no. 1 (2021): 152–61. http://dx.doi.org/10.15408/kauniyah.v14i1.16734.

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AbstrakBerbagai penelitian ilmiah telah membuktikan bahwa kolagen merupakan biomaterial ideal dalam aktivitas penyembuhan luka. Senyawa bioaktif pada madu dan Aloe vera dapat membantu meningkatkan pembentukan kolagen. Penelitian ini dilakukan untuk membandingkan pengaruh aplikasi topikal madu, gel Aloe vera, dan Moist Exposed Burn Ointment (MEBO) terhadap kepadatan kolagen pada proses penyembuhan luka bakar derajat dua pada tikus. Luka bakar dibuat pada 28 ekor tikus dan dibagi menjadi empat kelompok yang dipilih secara acak serta dilakukan aplikasi topikal harian dengan NaCl, madu, gel Aloe v
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AL-Dhamary, Nabhan, Adnan Al-Adhal, Hussein Kadi, and Mohammed Amood AL-Kamarany. "Investigation Effect of Aloe Vera in Fresh Gel Form on Rabbit’s Model Wound." Journal of Complementary and Alternative Medical Research 25, no. 3 (2024): 17–26. http://dx.doi.org/10.9734/jocamr/2024/v25i3522.

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Background: Aloe is plant possessing a great therapeutic potential in folk medicine in Yemen namely Aloe vera used as a multipurpose skin treatment.
 Objective: Therefore, this study aimed to investigate the effect of topical Aloe vera gel in fresh form on the wound healing of rabbit model in comparison with Moist Exposed Wound Ointment (MEBO) .
 Methods: The experimental animals as models of excision wounds that were classified into four groups. The 1st group was not treated as a control, the 2nd group was treated with a placebo (petroleum gel), the 3rd group was treated with Mebo a
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Suhartinah, Suhartinah. "UJI AKTIVITAS SEDIAAN GEL EKSTRAK DAUN KENIKIR (Cosmos caudatus Kunth) TERHADAP KECEPATAN PENYEMBUHAN LUKA SAYAT PADA PUNGGUNG KELINCI." Intan Husada : Jurnal Ilmiah Keperawatan 11, no. 01 (2023): 1–14. http://dx.doi.org/10.52236/ih.v11i1.259.

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Latar belakang
 Tanaman Kenikir (Cosmos caudatus Kunth) merupakan tanaman yang banyak tumbuh di Indonesia. Kandungan antioksidan dalam daun kenikir dapat mencegah kerusakan jaringan yang merangsang proses penyembuhan luka seperti flavonid, alkaloid, saponin dan tanin. Penelitian bertujuan untuk mengetahui apakah ekstrak daun Kenikir dapat diformulasikan sebagai sediaan gel yang memenuhi uji mutu fisik dan formulasi yang efektif terhadap kecepatan penyembuhan luka sayat pada punggung kelinci.
 Metode Penelitian
 Proses maserasi simplisia daun kenikir dengan etanol 96% untuk selan
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Hassan, Ahmed, Enji Ahmed, Dalia Ghalwash, and Azza Ezz Elarab. "Clinical Comparison of MEBO and Hyaluronic Acid Gel in the Management of Pain after Free Gingival Graft Harvesting: A Randomized Clinical Trial." International Journal of Dentistry 2021 (August 14, 2021): 1–10. http://dx.doi.org/10.1155/2021/2548665.

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Aim. This study aimed to compare the effect of MEBO versus 0.2% hyaluronic acid gel (Gengigel®) applied to the palatal donor site on postoperative pain reduction and wound healing after free gingival graft harvesting. Methodology. Thirty-nine patients with different mucogingival defects were included in this study for harvesting a free gingival graft (FGG) for soft tissue augmentation. Patients were randomly assigned into three equal groups: group I (MEBO), group II (0.2% HA Gengigel®), and group III (control). Postoperative pain was recorded by using the Visual Analogue Scale (VAS). Analgesic
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Refai, Hanan, Amira A. El-Gazar, Ghada M. Ragab, et al. "Enhanced Wound Healing Potential of Spirulina platensis Nanophytosomes: Metabolomic Profiling, Molecular Networking, and Modulation of HMGB-1 in an Excisional Wound Rat Model." Marine Drugs 21, no. 3 (2023): 149. http://dx.doi.org/10.3390/md21030149.

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Excisional wounds are considered one of the most common physical injuries. This study aims to test the effect of a nanophytosomal formulation loaded with a dried hydroalcoholic extract of S. platensis on promoting excisional wound healing. The Spirulina platensis nanophytosomal formulation (SPNP) containing 100 mg PC and 50 mg CH exhibited optimum physicochemical characteristics regarding particle size (598.40 ± 9.68 nm), zeta potential (−19.8 ± 0.49 mV), entrapment efficiency (62.76 ± 1.75%), and Q6h (74.00 ± 1.90%). It was selected to prepare an HPMC gel (SPNP-gel). Through metabolomic profi
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Hashad, Ingy M., Shaza H. Aly, Dalia O. Saleh, et al. "Mechanistic Wound Healing of Ficus trijuja Leaf Extract and Its Lipid Nanocapsule Supported by Metabolomic Profiling and In Vivo Studies." International Journal of Molecular Sciences 26, no. 3 (2025): 928. https://doi.org/10.3390/ijms26030928.

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This study explores the metabolic profile and wound-healing capabilities of Ficus trijuja, a species within the Moraceae family, for the first time. Ficus plants contain a variety of secondary metabolites such as flavonoids, triterpenoids, and alkaloids, known for their antioxidant, anti-inflammatory, and cytotoxic properties. Previous studies demonstrated the effectiveness of Ficus extracts in wound healing, with evidence of improved wound contraction, strength, and faster epithelization. This study shows the impact of F. trijuja extract in a gel base as well as when delivered through a lipid
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Huang, Yanfang, Sijia Li, Jinghua Pan, Congjing Song, Weiqiang Chen, and Yun Zhang. "Liquiritin Carbomer Gel Cold Paste Promotes Healing of Solar Dermatitis in Mice." International Journal of Molecular Sciences 25, no. 7 (2024): 3767. http://dx.doi.org/10.3390/ijms25073767.

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Ultraviolet radiation (UVR) has various effects on human cells and tissues, which can lead to a variety of skin diseases and cause inconvenience to people’s lives. Among them, solar dermatitis is one of the important risk factors for malignant melanoma, so prevention and treatment of solar dermatitis is very necessary. Additionally, liquiritin (LQ) has anti-inflammatory effects. In this study, we aimed to evaluate the anti-inflammatory and pro-wound healing effects of liquiritin carbomer gel cold paste (LQ-CG-CP) in vitro and in vivo. The results of MTT experiments showed no cytotoxicity of LQ
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Semieka, Mohamed A., Magda M. Ali, Sary Abdel Khafar, Al-lethie A. Al-lethie, and Enas Elmeligy. "Comparative Study of the Therapeutic Effect of Panthenol Gel and Mebo Ointment on Metacarpal Wound Healing in Donkeys." Journal of Equine Veterinary Science 74 (March 2019): 21–27. http://dx.doi.org/10.1016/j.jevs.2018.11.016.

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Najim, Safa Mustafa, Ammar A. Fadhil, Muhammed Naeem Abdullah, and Luma Eassa Hammodi. "Estimation of the healing effects of the topical use of MEBO and hyaluronic acid gel in the burned rats." Journal Of Advanced Pharmacy Education And Research 12, no. 2 (2022): 91–97. http://dx.doi.org/10.51847/jo4odidwgl.

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Andrade, Alexandre L., Aryane A. Pinheiro, Ellen A. Malveira, et al. "The Effect of a Photoactivated Ruthenium Nitrocomplex [RuCl(NO2)(dppb)(4,4-2 Mebipy)] on the Viability of Eukaryotic and Prokaryotic Cells, Including Bacterial Biofilms." Processes 12, no. 12 (2024): 2841. https://doi.org/10.3390/pr12122841.

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Antimicrobial resistance (AMR) is a critical global public health problem. Many bacterial pathogens use biofilm formation as their main pathogenicity mechanism, a practical tactic for surviving in natural settings and colonized host tissues. Research using ruthenium(II) complexes has demonstrated antibacterial action linked to photodynamic therapy, an alternate method of microbial control. Thus, in this work, the photosensitive nitro complex [RuCl(NO2)(dppb)(4,4-Mebipy)] (I) was prepared and the X-ray structure was determined. Then, we investigated the antibacterial and antibiofilm activities,
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Buzzaccaro, Stefano, Vincenzo Ruzzi, Tommaso Faleo, and Roberto Piazza. "Microrheology of a thermosensitive gelling polymer for cell culture." Journal of Chemical Physics, May 19, 2022. http://dx.doi.org/10.1063/5.0086533.

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We investigate the rheo-mechanical properties of Mebiol Gel®, a thermosensitive Gel-Forming Polymer extensively used as a medium for cellular culture, using passive microrheology made either by standard Dynamic Light Scattering(DLS) or by Photon Correlation Imaging (PCI). In the dilute limit, Mebiol displays a Newtonian behaviour with an effective viscosity that decreases with temperature, consistent with a peculiar aggregation mechanism characterized by anincrease of the molecular weight with a simultaneous reduction of the aggregate size. By increasing concentration and approaching gelation,
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"Application of a Thermo-Reversible Gelation Polymer, Mebiol Gel, for Stem Cell Culture and Regenerative Medicine." Journal of Stem Cells and Regenerative Medicine 6, no. 1 (2010): 10–14. http://dx.doi.org/10.46582/jsrm.0601003.

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Ohno, S., Y. Ohno, Y. Suzuki, et al. "Ingestion of Tabebuia avellanedae (Taheebo) Inhibits Production of Reactive Oxygen Species from Human Peripheral Blood Neutrophils." November 19, 2015. https://doi.org/10.19070/2326-3350-SI06001.

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Neutrophils are a main source of oxidative stress due to reactive oxygen species (ROS) production, and the tissue damage caused by excessive ROS might lead to aging and a variety of diseases. Whereas the anti-inflammatory effects of Tabebuia avellanedae (taheebo) have been reported in vitro and in animal experiments, little is known about the effects of taheebo in humans. Fourteen adult volunteers ingested 500 mg of taheebo extract in 4 capsules (Taheebo Japan, Co., Ltd., Osaka, Japan) daily for 2 weeks. The production of ROS from peripheral blood neutrophils was measured by luminol-dependent
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A., Pattnaik, Mukherjee S., Sarkar R., et al. "EHydrogel Formulation of Buchanania lanzan Spreng-A Focus on Rheological Properties." International Journal of Drug Delivery Technology 5, no. 3 (2015). http://dx.doi.org/10.25258/ijddt.v5i3.8879.

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The aim of this study was to characterize and optimize the different hydrogel formulations of the methanolic root extract of Buchanania lanzan (MEBL) with an objective towards the development of a suitable topical delivery system. The gel formulations were prepared with different concentrations of polymer (Carbopol-940) and 0.5% of the active fraction (ethyl acetate sub-fraction of MEBL). Different hydrogel formulations were analyzed for rheological properties, spreadability, homogeneity and stability. A comparative study of rheological parameters, and spreadability showed that the gel formula
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Musyeva, Shoira. "“HAVAS COMFORT MEBEL” MChJda marketing xizmatini tashkillashtirish va uning samaradorligini oshirish yo‘llari." YASHIL IQTISODIYOT VA TARAQQIYOT 1, no. 11-12 (2023). http://dx.doi.org/10.55439/ged/vol1_iss11-12/a354.

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Mazkur maqolada ishlab chiqarish korxonasida marketing konsepsiyasining mazmun-mohiyati va zamonaviyshakllarini tadqiq qilish, mebel ishlab chiqarish sohasining bugungi holati va marketing xizmatining faoliyatini tahlil qilish,marketing faoliyatini tahlil qilish, uning alohida jihatlarini ochib berish, marketing xizmatlarini shakllantirish bo‘yicha takliflarishlab chiqish ko‘rib chiqilgan.
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Angriani, Meilyana, Novrianti Novrianti, Neneng Purnamawati, Idham Khalid, Richa Melysa, and Ayyi Husbani. "Analisis Pengaruh Karbon Aktif Serbuk Gergaji Kayu Jati terhadap Filtration Loss dan Rheology Lumpur Pemboran." Jurnal Global Ilmiah 1, no. 12 (2024). http://dx.doi.org/10.55324/jgi.v1i12.121.

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Rheology lumpur dan filtration loss merupakan sifat fisik yang harus yang harus dikontrol karena dapat membantu mengontrol tekanan formasi, mengetahui kemampuan lumpur dalam serpih bor pada saat pemboran dihentikan dan mengangkat padatan bor. Untuk mendapatkan hasil filtration loss dan rheology yang sesuai, perlu ditambahkan additive didalam lumpur pemboran. Salah satu additive yang dipergunakan adalah karbon aktif. Serbuk gergaji kayu jati merupakan limbah dari hasil pemotongan furniture atau mebel yang jarang digunakan dan kemudian dimanfaatkan menjadi karbon aktif. Kayu jati memiliki kandun
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Kamal, Nagham H., Fatema R. Saber, Abeer Salama, et al. "Enhanced wound healing activity of naturally derived Lagenaria siceraria seed oil binary nanoethosomal gel: formulation, characterization, in vitro/in vivo efficiency." Future Journal of Pharmaceutical Sciences 10, no. 1 (2024). http://dx.doi.org/10.1186/s43094-024-00678-2.

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Abstract Background The present study aims to enhance the wound healing potential of the seed oil (SO) of Lagenaria siceraria (Egyptian cultivar) via the preparation of SO-loaded binary nanoethosomal (SO-BNE) gels. SO-BNEs were prepared using 23 factorial design, characterized for vesicle size, zeta potential, polydispersity index, linoleic and oleic acid EE% for ensuring improved skin permeability. The L. siceraria SO, optimized SO-BNE gels (0.5% and 5%) and Mebo® were topically applied in full-thickness wounded rat model twice daily for 10 days. Results In the SO-BNE gel groups, the normal a
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Ali, Mawada Mohamed, Asmaa Khairy Al-Mokaddem, Essam Abdel-Sattar, et al. "Enhanced wound healing potential of arabincoside B isolated from Caralluma Arabica in rat model; a possible dressing in veterinary practice." BMC Veterinary Research 20, no. 1 (2024). http://dx.doi.org/10.1186/s12917-024-04128-2.

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Abstract Background Wound management is a critical procedure in veterinary practice. A wound is an injury that requires the body’s cells’ alignment to break down due to external assault, such as trauma, burns, accidents, and diseases. Re-epithelization, extracellular matrix deposition, especially collagen, inflammatory cell infiltration, and development of new blood capillaries are the four features that are used to evaluate the healing process. Using a natural extract for wound management is preferred to avoid the side effects of synthetic drugs. The current study aimed to assess the effect o
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