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Rozprawy doktorskie na temat „Medicinal applications”

Autor: Grafiati

Data publikacji: 2 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Carnahan, Melinda K. "Novel Nitric Oxide Donors for Use in Medicinal Applications." University of Akron / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=akron1247504255.

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Lima, Barbosa Ana Soraya. "Organometallic compounds of tin and ruthenium : applications in medicinal chemistry." Thesis, Strasbourg, 2016. http://www.theses.fr/2016STRAF029.

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Nous avons synthétisé des composés d'étain avec des acides undécylénique, ricinoléique et caprylique. Ils ont une activité importante contre certaines souches de microrganismes, puisque ils agissent pour certains d’entre eux à des concentrations nanomolaires. Staphylococcus aureus semble être 4000 fois plus sensible à leur toxicité que les cellules de mammifères. Nous avons obtenu des composés du ruthénium qui présentent cytotoxicité contre des cellules cancéreuses suivant un mécanisme d'action différent de ceux observés pour le Cisplatine ou d'autres composés de Ru, grâce à leur grande stabil

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3

Di, Martino Giovanni Paolo <1985&gt. "Computational Methods in Biophysics and Medicinal Chemistry: Applications and Challenges." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amsdottorato.unibo.it/6329/1/Dissertation_Di_Martino.pdf.

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In this thesis I described the theory and application of several computational methods in solving medicinal chemistry and biophysical tasks. I pointed out to the valuable information which could be achieved by means of computer simulations and to the possibility to predict the outcome of traditional experiments. Nowadays, computer represents an invaluable tool for chemists. In particular, the main topics of my research consisted in the development of an automated docking protocol for the voltage-gated hERG potassium channel blockers, and the investigation of the catalytic mechanism of the hum

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4

Di, Martino Giovanni Paolo <1985&gt. "Computational Methods in Biophysics and Medicinal Chemistry: Applications and Challenges." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amsdottorato.unibo.it/6329/.

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In this thesis I described the theory and application of several computational methods in solving medicinal chemistry and biophysical tasks. I pointed out to the valuable information which could be achieved by means of computer simulations and to the possibility to predict the outcome of traditional experiments. Nowadays, computer represents an invaluable tool for chemists. In particular, the main topics of my research consisted in the development of an automated docking protocol for the voltage-gated hERG potassium channel blockers, and the investigation of the catalytic mechanism of the hum

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5

Feula, Antonio. "Synthesis of azetidines and pyrrolidines : towards medicinal chemistry and organocatalysis applications." Thesis, University of Birmingham, 2013. http://etheses.bham.ac.uk//id/eprint/4214/.

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Room temperature iodocyclisation of homoallylamines stereoselectively delivers functionalised 2- (iodomethyl)azetidine derivatives in high yield. Increasing reaction temperature from 20 °C to 50 °C switches the reaction outcome to realise the stereoselective formation of functionalised 3-iodopyrrolidine derivatives. It was shown that these pyrrolidines are formed via thermal isomerisation of the aforementioned azetidines. Primary and secondary amines could be reacted with iodomethyl azetidine derivatives to deliver stable methylamino azetidine derivatives. With subtle changes to the reaction s

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6

Hindi, Khadijah M. "The Medicinal Applications and Stability Evaluation of Silver (I) Carbene Complexes." University of Akron / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=akron1217301493.

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7

Gandy, Justin John. "The medicinal properties and applications of a carbohydrate derived fulvic acid." Thesis, University of Pretoria, 2015. http://hdl.handle.net/2263/56957.

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Background: Carbohydrate derived fulvic acid (CHD-FA) is a synthetic heavy metal free fulvic acid. Although CHD-FA has been suggested as a nutritional supplement and even a medication, there is currently no data available with regards to the systemic kinetics of CHDFA when ingested orally. Fulvic acid has shown equivalence when compared to diclofenac sodium and betamethasone in a murine hypersensitivity model when applied topically with no adverse side effects. Data from several animal studies indicate that fulvic acid administered topically or orally is safe and effective as an anti-inf

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8

Dong, Mouzhi. "Data mining of classic Chinese medicinal formulae using artificial neural network." HKBU Institutional Repository, 2000. http://repository.hkbu.edu.hk/etd_ra/228.

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9

Gačanin, Jasmina [Verfasser]. "Design and Synthesis of Multifunctional Hybrid Hydrogels for Medicinal Applications / Jasmina Gačanin." Ulm : Universität Ulm, 2021. http://d-nb.info/123552843X/34.

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10

Altemimi, Ammar Badran. "ULTRASONIC APPLICATIONS- PHYTOCHEMICAL ANALYSES OF SOME MEDICINAL NATURAL PRODUCTS IN FOOD PLANTS." OpenSIUC, 2016. https://opensiuc.lib.siu.edu/dissertations/1149.

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There are concerns about using synthetic phenolic antioxidants such as butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) as food additives because negative effects to human health have been reported. thus, a replacement of these synthetics by antioxidant extractions from various foods has been proposed. By the generation of more than eight thousand different phenolics, fruits and vegetables are the prime sources of natural antioxidants. The consumption of fruits and vegetables has been strongly linked with several health benefits, a result of their medicinal properties and high

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11

Martyn, Derek Craig. "Nitrogenous heterocycles : modulation of chemical properties, and applications to synthetic and medicinal chemistry." Thesis, University of Canterbury. Chemistry, 2003. http://hdl.handle.net/10092/5650.

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This thesis examines ways in which the chemical reactivity of benzimidazole-, pyrrole- or pyrrolizinone-based heterocycles can be modulated. The latent reactivity of these systems has been used to develop enzyme inhibitors, antitumour compounds and a novel amino acid derivatisation technique. Chapter One introduces the concept of modulated chemical reactivity, with illustrative examples from biochemistry, synthesis and medicinal chemistry. The application of latent reactivity towards the inhibition of serine proteases, a class of proteolytic enzymes, is then reviewed. Two inhibitor classes ar

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12

Rotella, David Paul. "The synthon concept in medicinal chemistry : synthesis and applications of cyclohexane diol diamines /." The Ohio State University, 1985. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487263399027046.

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13

Trejos, Alejandro. "Palladium-Catalysed Couplings in Organic Synthesis : Exploring Catalyst-Presenting Strategies and Medicinal Chemistry Applications." Doctoral thesis, Uppsala universitet, Avdelningen för organisk farmaceutisk kemi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-173068.

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Palladium-catalysed coupling reactions have been embraced by synthetic chemists as one of the preferred means for smooth formation of new carbon-carbon bonds: a truly ubiquitous methodology of synthesizing complex molecules. This thesis describes the study of a series of palladium(0)-catalysed C2-arylations of a 1-cyclopentenyl ether, equipped with a chiral (S)-N-methyl-pyrrolidine auxiliary. The investigated olefin was demonstrated to undergo Si-face insertion, providing (R)-configuration of the arylated C2-carbon. In addition, the mild and novel palladium(II)-catalysed dominoHeck/Suzuki β,α-

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14

Rossi, Emiliano. "Micro/Meso-Structured Reactors for Chemical Synthesis: Applications in Materials Science and Medicinal Chemistry." Doctoral thesis, Università degli studi di Padova, 2012. http://hdl.handle.net/11577/3422956.

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The research afforded during the present PhD project deals with the application of microfluidic technology for designing new synthetic methods. Compounds with potential applications in medicinal chemistry and material science were considered, with a focus on process suitability for large scale productions. In this optic, development and scaling up of a continuous flow process for safe handling of diazomethane to large scale was afforded. Such study was carried out during a period of three months spent at Corning European Technology Center (CETC) of Avon, France, and the results obtained were

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15

Kay, Richard D. "Complexes of functionalised polyamines with diagnostic and therapeutic applications." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342468.

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16

Hartman, Alwin Mathijs [Verfasser], and A. K. H. [Akademischer Betreuer] Hirsch. "New applications of dynamic combinatorial chemistry to medicinal chemistry / Alwin Mathijs Hartman ; Betreuer: A.K.H. Hirsch." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2019. http://d-nb.info/1201647282/34.

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17

Cho, C. C. "Development of novel endothelial cell culture systems and their applications in studying angiogenesis modulators from medicinal plants." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597625.

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The impact of the different culture media on human umbilical vein endothelial cells (HUVECs) and their responses to external treatments were examined. A new modified medium, MM, was developed by modifying a widely used endothelial cell growth medium – EGM-2. MM allows detection of the stimulatory effects of VEGF and other pro-angiogenic substances in the MTS cell proliferation assay and HUVEC-fibroblast tube formation assay and remains suitable for testing anti-angiogenic substances. Culture medium has a significant impact on HUVECs’ responsiveness to angiogenesis modulators and their conseque

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18

Estevão, Mónica Alexandra Silva. "Applications of the indole scaffold in medicinal chemistry: development of new antioxidants, COX inhibitors and antitubercular agents." Doctoral thesis, Faculdade de Ciências e Tecnologia, 2014. http://hdl.handle.net/10362/12435.

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19

Orrling, Kristina M. "On the Versatility of Microwave-Assisted Chemistry : Exemplified by Applications in Medicinal Chemistry, Heterocyclic Chemistry and Biochemistry." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-101356.

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20

Craig, Sandra Navonne. "The Design and Evaluation of Boronic Acid Derivatives for the Recognition of Cell Surface Carbohydrates for Medicinal Applications." Digital Archive @ GSU, 2008. http://digitalarchive.gsu.edu/chemistry_diss/29.

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ABSTRACT Carbohydrates in various forms play vital roles in numerous critical biological processes including cell-cell adhesion and communication, embryo development, immune response, etc. Fluorescent sensors for such carbohydrates have a wide range of potential applications including glucose concentration determination, cell labeling and targeting based on carbohydrate biomarkers, as in vitro diagnostic tools, and biomarker-directed cellular imaging. Our group has been interested in the design and synthesis of multi-boronic acid compounds with well-defined three-dimensional scaffolding for t

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21

McQueen, Adonis. "Synthesis, in vitro Characterization and Applications of Novel 8-Aminoquinoline Fluorescent Probes." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/7062.

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Malaria is a parasitic disease that is caused by the plasmodium parasite. Plasmodium infection has affected man for thousands of years. With advances in drug discovery over the past century, malaria has evolved to possess resistance to most mainline therapeutics. This war of drug discovery vs plasmodium evolution continues to be fought to this very day, with attempts to eradicate malaria worldwide. Frontline treatments such as chloroquine, artemisinin, and atovaquone/proguanil have all seen parasitic resistance in strains of P. vivax as well as P. f

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22

Arvela, Riina K. "Palladium-Catalysed Carbon–Carbon Coupling Reactions : Focusing on Microwave Heating, Low Catalyst Concentrations, Aqueous Conditions, Regioselectivity and Medicinal Chemistry Applications." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-99776.

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23

Gessner, Isabel [Verfasser]. "Chemically Engineered Iron Oxide and Carbon Nanostructures for Medicinal Applications: Bioconjugation Strategies for Next Generation in vitro and ex vivo Theranostics / Isabel Gessner." München : Verlag Dr. Hut, 2019. http://d-nb.info/1178898938/34.

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24

Frischkorn, Kate E. "Preparation of Supramolecular Amphiphilic Cyclodextrin Bilayer Vesicles for Pharmaceutical Applications." DigitalCommons@CalPoly, 2018. https://digitalcommons.calpoly.edu/theses/1894.

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Recent pharmaceutical developments have investigated using supramolecular nanoparticles in order to increase the bioavailability and solubility of drugs delivered in various methods. Modification of the carbohydrate cyclodextrin increases the ability to encapsulate hydrophobic pharmaceutical molecules by forming a carrier with a hydrophobic core and hydrophilic exterior. Guest molecules are commonly added to these inclusion complexes in order to add stability and further increase targeting abilities of the carriers. One such guest molecule is adamantine combined with a poly(ethylene glycol) ch

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25

Zayas, Jessica. "Strain Promoted Click Chemistry of 8-Azidopurine and 5-Azidopyrimidine Nucleosides and Nucleotides with Cyclooctynes and Applications to Living Cell Imaging." FIU Digital Commons, 2015. http://digitalcommons.fiu.edu/etd/2176.

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The strain promoted azide alkyne cycloaddition (SPAAC) of azido nucleobase modified nucleosides and nucleotides with cyclooctynes to give fluorescent triazoles has been relatively unexplored. Thus, SPAAC between azido-nucleobases and various cyclooctynes in aqueous solution at ambient temperature resulted in the efficient formation (3 min - 2 h) of triazole products with inherent fluorescent properties. The 2- and 8-azidoadenine nucleosides reacted with fused cyclopropyl cyclooctyne, dibenzylcyclooctyne or monofluorocyclooctyne to produce click products functionalized with hydroxyl, amino, N-h

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26

Batra, Sumit. "Innovative Purification Protocol for Heparin Binding Proteins: Relevance in Biopharmaceutical and Biomedical Applications." TopSCHOLAR®, 2011. http://digitalcommons.wku.edu/theses/1062.

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Heparin binding (HB) proteins mediates a wide range of important cellular processes, which makes this class of proteins biopharmaceutically important. Engineering HB proteins could bring many advantages, but it necessitates cost effective and efficient purification methodologies compared to the currently available methods. One of the most important classes of heparin binding protein is the fibroblast growth factors (FGFs) and its receptors (FGFRs). In this study, we report an efficient off-column purification of FGF-1 from soluble fractions and purification of the D2 domain of FGFR from insolu

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27

Vettorato, Elisa. "Development of transdermal delivery systems for innovative clinical applications of cannabinoids." Doctoral thesis, Università degli studi di Padova, 2019. http://hdl.handle.net/11577/3422356.

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The use of cannabis for medicinal purposes is deeply rooted in history, dating back to ancient times. While there has been a strong push for legalizing medicinal cannabis and research, conclusive evidence regarding the short- and long-term health effects (harms and benefits) of cannabis use remains elusive because of a high variability when cannabinoids are administered orally or by inhalation. Transdermal delivery of cannabinoids could allow a constant, defined release of these active ingredients. The main goal of this project was to develop innovative pharmaceutical forms in order to ensure

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28

Mezo, Vilma Marlene Maciel. "Estudo farmacognóstico comparativo de espécies medicinais de Passiflora L.: P.alata Curtis; P.caerulea L.; P.edulis Sims. forma flavicarpa Degener; P.incarnata L. e P.quadrangularis L." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/9/9138/tde-16012018-151326/.

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O elevado índice de pessoas afetadas pela ansiedade tem levado os pesquisadores a buscarem novas alternativas de tratamento. A fitoterapia tem empregado medicamentos contendo algumas espécies de Passiflora, conhecidas popularmente como \"maracujá\". As folhas de P.alata oficializadas na Farmacopéia Brasileira e os órgãos aéreos de P.incarnata, inscrita em farmacopeias estrangeiras, são matéria-prima para a elaboração de diversos medicamentos fitoterápicos. No entanto, as semelhanças morfológicas entre plantas medicinais deste gênero geram erros e falsificações. Considerando este fato, constitu

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29

Elam, Chanda LaVortriette. "Synthesis and Functionality of Polymeric Diazeniumdiolates in the Use and Control of Nitric Oxide Release for Severe Medicinal Atherosclerotic Plaque Applications and Human Papillomavirus Treatment." University of Akron / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=akron1218691731.

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30

Sachdeva, Sameer. "Design and applications of antibody mimics against epidermal growth factor receptor." Scholarly Commons, 2015. https://scholarlycommons.pacific.edu/uop_etds/132.

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Antibodies have been widely used as reagents, homing devices, diagnostics and as therapeutic agents against different targets in clinic and research. Recently a number of monoclonal antibodies and their drug conjugates have been approved as therapeutic agents. While these molecules have great potential in various applications and therapeutics, extensive use of full length antibodies has been hampered by the high cost of production, large molecular weight and limited ability to penetrate tumor tissues. These limitations have led to the research for antibody alternatives with lower molecular wei

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31

Saletti, Mario. "A multidisciplinary approach to the development of innovative tools for pharmaceutical and technological applications." Doctoral thesis, Università di Siena, 2023. https://hdl.handle.net/11365/1227081.

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The research activity carried out during the Ph.D. in Chemical and Pharmaceutical Sciences has regarded the design, synthesis, and characterization of innovative tools relevant to both pharmaceutical and technological fields. Great interest has been dedicated to the investigation of the “affinity polymerization” mechanism of novel polymeric materials founded on repetitive monomeric units based on the 3-phenylbenzofulvene scaffold that spontaneously polymerize by simple removal of the solvent. In this context, the attention has been focused on the synthesis of novel benzofulvene-based derivativ

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32

Peralta, Donna V. "Synthesis and Applications of Mutimodal Hybrid Albumin Nanoparticles for Chemotherapeutic Drug Delivery and Phototherml Therapy Platforms." ScholarWorks@UNO, 2014. http://scholarworks.uno.edu/td/1886.

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Progress has been made in using human serum albumin nanoparticles (HSAPs) as carrier systems for targeted treatment of cancer. Human serum albumin (HSA), the most abundant human blood protein, can form HSAPs via a desolvation and crosslinking method, with the size of the HSAPs having crucial importance for drug loading and in vivo performance. Gold nanoparticles have also gained medicinal attention due to their ability to absorb near-infrared (NIR) light. These relatively non-toxic particles offer combinational therapy via imaging and photothermal therapy (PPTT) capabilities. A desolvation and

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33

Lee, Kim Chung. "Liquid chromatography coupled with electrospray-ionization mass spectrometry and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry method development and applications for the analysis of food and medicinal herbs." HKBU Institutional Repository, 2009. http://repository.hkbu.edu.hk/etd_ra/995.

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34

Balderrama, Martínez Sotomayor Raúl. "Développement de ligands de cuivre pour des applications thérapeutiques." Electronic Thesis or Diss., Aix-Marseille, 2020. http://www.theses.fr/2020AIXM0449.

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Le cuivre est un métal endogène et redox actif présent dans plusieurs protéines et enzymes essentielles à la vie et joue un rôle important dans différents processus biologiques. Cependant, son activité redox rend également le Cu potentiellement toxique car il peut favoriser la formation d'espèces réactives de l'oxygène (ROS). Ce comportement à double tranchant intéresse les chercheurs depuis longtemps et son exploitation est cruciale pour développer des complexes de Cu aux propriétés thérapeutiques. Dans ce travail de thèse, différents ligands pour la coordination du Cu ont été conçus et explo

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35

Zhao, Xiaoning. "Synthesis and applications of functional magnetic polymer beads; synthesis and mass spectrometry analysis of model peptides." Scholarly Commons, 2012. https://scholarlycommons.pacific.edu/uop_etds/156.

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The first part of the thesis describes the synthesis and application of functional magnetic polymer beads. The traditional suspension polymerization approach was used to synthesize polystyrene-iron oxide (Fe 3 O 4 ) based magnetic beads. The beads were coupled to different surface functional groups. The Fe 3 O 4 particles were encapsulated into a polystyrene shell. The surface functional groups were generated by graft-polymerization with functional monomers. The average size of the beads was in the range of 100-500 μm. Chemical tests showed that the beads were stable in strong acid, strong bas

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36

Hofstetter, Robert Klaus Verfasser], Andreas [Akademischer Betreuer] Link, Andreas [Gutachter] Link, Maria Kristina [Gutachter] Parr, and Gerhard [Gutachter] [Scriba. "Interfaces of Supercritical Fluid Chromatography with Mass Spectrometry and Supercritical Fluid Extraction - Applications in Medicinal Chemistry and Bioanalysis / Robert Klaus Hofstetter ; Gutachter: Andreas Link, Maria Kristina Parr, Gerhard Scriba ; Betreuer: Andreas Link." Greifswald : Universität Greifswald, 2020. http://nbn-resolving.de/urn:nbn:de:gbv:9-opus-40389.

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Hofstetter, Robert Klaus [Verfasser], Andreas [Akademischer Betreuer] Link, Andreas [Gutachter] Link, Maria Kristina [Gutachter] Parr, and Gerhard [Gutachter] Scriba. "Interfaces of Supercritical Fluid Chromatography with Mass Spectrometry and Supercritical Fluid Extraction - Applications in Medicinal Chemistry and Bioanalysis / Robert Klaus Hofstetter ; Gutachter: Andreas Link, Maria Kristina Parr, Gerhard Scriba ; Betreuer: Andreas Link." Greifswald : Universität Greifswald, 2020. http://d-nb.info/1220424730/34.

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Shava, Soul. "Indigenous knowledges: a genealogy of representations and applications in developing contexts of environmental education and development in southern Africa." Thesis, Rhodes University, 2009. http://hdl.handle.net/10962/d1005920.

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This study was developed around concerns about how indigenous knowledges have been represented and applied in environment and development education. The first phase of the study is a genealogical analysis after Michel Foucault. This probes representations and applications of plant-based indigenous knowledge in selected anthropological, botanical and environmental education texts in southern Africa. The emerging insights were deepened using a Social (Critical) Realism vantage point after Margaret Archer to shed light on agential issues in environmental education and development contexts. Here h

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39

Cockroft, Nicholas T. "Applications of Cheminformatics for the Analysis of Proteolysis Targeting Chimeras and the Development of Natural Product Computational Target Fishing Models." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu156596730476322.

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40

Curtis, Matthew Earl. "Investigation and characterization of the Direct Analysis in Real Time helium metastable beam open-air ion source: Mechanism of ionization, fluid dynamic visualization, and applications." Scholarly Commons, 2013. https://scholarlycommons.pacific.edu/uop_etds/146.

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The DART ion source was introduced in 2005 at the ASMS Sanibel Conference and immediately afterward Professor Sparkman was contemplating of a way to get our lab this revolutionary mass spectrometry ionization technique. It did not take long because it was delivered to the Pacific Mass Spectrometry Facility in August 2006 and I was able to being using and learning the technique. The ion source creates excited state helium metastables (2 3 S) with an ionization potential of 19.8 eV are created by a glow discharge at atmospheric pressure. The metastables are sent through an optional heater, to ai

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41

Ni, Nanting. "Application of Boronic Acids in Medicinal Chemistry (Inhibitors, Sensors)." Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/chemistry_diss/34.

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It is well known boronic acids have its unique chemistry and related applications in organic synthesis. The boronic acid functionally group also plays very important roles in medicinal chemistry and chemical biology. For example, boronic acids have been developed as potential therapeutic agents, chemical biology tools. All these applications are directly related to the unique electronic and chemical properties of the boronic acid group. Herein, several application of boronic acids have been studied: 1) several groups of compounds were found as bacterial quorum sensing inhibitors; 2) a boronate

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42

Thompson, J. R. "Applications of pattern recognition in medicine." Thesis, Open University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377939.

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43

Sylvestre, Jean-Philippe. "Applications of iontophoresis in sports medicine." Thesis, University of Bath, 2007. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.486478.

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In this thesis, two potential applications of transdermal iontophoresis in the field of sports medicine were studied: (1) the local delivery of dexamethasone phosphate (Dex-Phos), a corticosteroid used to treat musculoskeletal inflammation, and (2) the extraction of systemic amino acids (AAs), potential biological markers of fatigue in athletes. The iontophoretic delivery of Dex-Phos was studied, in vitro, in order to evaluate the effects of competing ions and electroosmosis, and identify the optimal conditions for its delivery. The iontophoretic extraction of AAs from the skin was first studi

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44

MUSCOLINO, Emanuela. "Polysaccharide hydrogels for regenerative medicine applications." Doctoral thesis, Università degli Studi di Palermo, 2022. http://hdl.handle.net/10447/535885.

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Wang, Dongren. "Vanadium complexes and clusters for (potential) industrial and medicinal application." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=965367258.

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Schwehm, Carolin Maria. "Synthesis of 3-dimensional scaffolds for application in medicinal chemistry." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/32362/.

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In this thesis the successful synthesis of a novel tricyclic scaffold containing a ring fused triazole and piperidine will be discussed and furthermore its utility as a new potential privileged structure will be evaluated. As starting material for the synthesis of the considered scaffolds the commercially available ethyl 4-oxopiperidine-1-carboxylate 108 was used. Piperidone 108 was converted into scaffolds 96, 97 and 98 alternating the ring size (n=1, 2, 3) of the fused bicyclic ring. This tricyclic triazole scaffold was incorporated into known biologically active molecules (Sitaglitpin, a DP

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Swarup, Ashish, and ash198@gmail com. "Application of Traditional Medicines on Textiles." RMIT University. Fashion and Textiles, 2007. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080521.114106.

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As science and technology has developed, the manner by which drugs can be delivered has grown. This research explores an alternative method for the delivery of therapeutic compounds to the body. The basis of the study involves the application of traditional medicines on textiles. Boswellia Serrata Extract (B.S.E.) is a common traditional medicine used for curing body pains. The most common form of B.S.E. based products are creams that are applied directly to the skin. Experiments show that these creams were not suitable as a basis for applying to textile materials because the creams cont

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Valastyán, Iván. "Applications of tomographic imaging in nuclear medicine." Licentiate thesis, KTH, Physics, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4187.

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Valastyán, Iván. "Applications of tomographic imaging in nuclear medicine /." Stockholm : School of engineering sciences, Royal Institute of Technology, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4187.

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Simonini, Marina. "Fractal sets and their applications in medicine." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/8763/.

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La geometria euclidea risulta spesso inadeguata a descrivere le forme della natura. I Frattali, oggetti interrotti e irregolari, come indica il nome stesso, sono più adatti a rappresentare la forma frastagliata delle linee costiere o altri elementi naturali. Lo strumento necessario per studiare rigorosamente i frattali sono i teoremi riguardanti la misura di Hausdorff, con i quali possono definirsi gli s-sets, dove s è la dimensione di Hausdorff. Se s non è intero, l'insieme in gioco può riconoscersi come frattale e non presenta tangenti e densità in quasi nessun punto. I frattali più classici

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