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1

Cheng, Shaun Kian Hong, and Khoon Leong Chuah. "Metastatic Renal Cell Carcinoma to the Pancreas: A Review." Archives of Pathology & Laboratory Medicine 140, no. 6 (2016): 598–602. http://dx.doi.org/10.5858/arpa.2015-0135-rs.

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The pancreas is an unusual site for tumor metastasis, accounting for only 2% to 5% of all malignancies affecting the pancreas. The more common metastases affecting the pancreas include renal cell carcinomas, melanomas, colorectal carcinomas, breast carcinomas, and sarcomas. Although pancreatic involvement by nonrenal malignancies indicates widespread systemic disease, metastatic renal cell carcinoma to the pancreas often represents an isolated event and is thus amenable to surgical resection, which is associated with long-term survival. As such, it is important to accurately diagnose pancreati
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Wahyuni, Siska Dwiyantie, Sri Suryanti, Hasrayati Agustina, and Bethy Suryawathy Hernowo. "The Association of Clinicopathological Features with Metastatic Status in Infiltrative Urothelial Carcinoma of Bladder." Journal of Drug Delivery and Therapeutics 10, no. 6-s (2020): 99–102. http://dx.doi.org/10.22270/jddt.v10i6-s.4647.

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Background: Infiltrative urothelial carcinoma of bladder is an aggressive variant of bladder carcinoma. Most of the patients in their first encounter with doctors are diagnosed with advanced stages and many has metastasized. Metastasis is a process of malignant tumor cells migrating from its primary tumor location to other organs or sites inside the body via blood circulation or lymphatic system. Metastasis process is responsible for 90% cancer deaths compared to the primary tumor itself, infiltrative urothelial carcinoma of bladder. To reduce mortality, knowledge of the clinicopathological ch
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ÇEÇEN, Ayşe, Esra KAVAZ, and Seda GÜN. "The clinical and prognostic value of the neutrophil lymphocyte ratio, the platelet lymphocyte ratio and mean platelet volume in tinnitus patients." Journal of Experimental and Clinical Medicine 38, no. 3 (2021): 251–54. http://dx.doi.org/10.52142/omujecm.38.3.8.

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Approximately 15% of renal cell carcinomas metastasize to the head and neck region. Here in, we report a rare case report of a patient who underwent nephrectomy for renal cell carcinoma (RCC) ten years ago and presented with metastatic renal cell carcinoma on her lower lip. A 65-year-old woman presented with a rapidly growing mass on the lower lip. Pathology report resulted in renal cell carcinoma metastasis. Although metastatic renal cell carcinoma to the head and neck is uncommon, metastasis should be considered in the differential diagnosis of a rapidly growing vascular lesion in the head a
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ÇEÇEN, Ayşe, Esra KAVAZ, and Seda GÜN. "A rare case: Renal cell carcinoma metastasis to lower lip." Journal of Experimental and Clinical Medicine 38, no. 3 (2021): 396–97. http://dx.doi.org/10.52142/omujecm.38.3.38.

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Approximately 15% of renal cell carcinomas metastasize to the head and neck region. Here in, we report a rare case report of a patient who underwent nephrectomy for renal cell carcinoma (RCC) ten years ago and presented with metastatic renal cell carcinoma on her lower lip. A 65-year-old woman presented with a rapidly growing mass on the lower lip. Pathology report resulted in renal cell carcinoma metastasis. Although metastatic renal cell carcinoma to the head and neck is uncommon, metastasis should be considered in the differential diagnosis of a rapidly growing vascular lesion in the head a
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5

Ali, Sundus, Adnan Qasim, Rahmatullah Salah, Muhammad Rizwan Sarwar, Muhammad Usman, and Shahzad Shams. "Isolated late intradural cauda equina metastasis of renal cell carcinoma." Surgical Neurology International 12 (September 30, 2021): 481. http://dx.doi.org/10.25259/sni_721_2021.

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Background: The cauda equina (CE) is the most common site for intradural extramedullary metastasis from systemic malignancies such as lung, breast, and thyroid carcinomas. However, renal cell carcinomas (RCC), with their high metastatic potential, are rarely responsible for CE metastatic lesions. Here, we report an intradural cauda equina mass, as the first and only site of metastasis of a renal cell carcinoma. Case Description: A 55-year-old female had undergone a left nephrectomy for renal cell carcinoma 8 years ago. She now presented with a unifocal renal cell metastasis to the CE. As such
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6

Liang, Huasheng, Yuhua Zhong, Zuojie Luo, et al. "Assessment of Biomarkers for Clinical Diagnosis of Papillary Thyroid Carcinoma with Distant Metastasis." International Journal of Biological Markers 25, no. 1 (2010): 38–45. http://dx.doi.org/10.1177/172460081002500106.

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Early diagnosis and treatment of thyroid cancers are critical for better prognosis and better survival rates. The purpose of this study was to identify potential diagnostic markers for papillary thyroid carcinomas with distant metastasis. Fifty-eight papillary thyroid tumor specimens (27 papillary thyroid carcinomas with distant metastasis and 31 without metastasis) were examined, and protein expression of pituitary tumor-transforming gene (PTTG), E-cadherin, p27kip1, vascular endothelial growth factor (VEGF)-C, metalloproteinase (MMP) 2, MMP9, chemokine receptor CXCR4, and basic fibroblast gr
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7

Nunez, D. A., C. G. C. Sutherland, and R. K. Sood. "Breast metastasis from a pharyngeal carcinoma." Journal of Laryngology & Otology 103, no. 2 (1989): 227–28. http://dx.doi.org/10.1017/s0022215100108540.

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AbstractThe reported incidence of metastatic disease in head and neck cancer is increasing. The most common site of metastatic involvement in squamous carcinoma of the head and neck is the lung followed by liver, mediastinal nodes and bone. The breast is rarely infiltrated by metastatic disease, 2 per cent or less of clinically detected breast lumps being of nonmammary origin, most frequently malignant melanoma, lymphoma/leukaemia and primary lung carcinoma.A 73-year-old female presented with a primary posterior pharyngeal wall squamous carcinoma and bilateral enlarged neck nodes. She develope
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8

Xu, K., Q. Ye, L. Han, and M. Zhong. "A Comparative Analysis of Immunohistochemical Profile of Primary and Metastatic Endometrial Endometrioid Carcinoma." American Journal of Clinical Pathology 154, Supplement_1 (2020): S32—S33. http://dx.doi.org/10.1093/ajcp/aqaa161.066.

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Abstract Introduction/Objective Beta catenin plays an important role in cancer tumorigenesis and have been found to be associated with metastasis in a variety of tumors. Analyzing TCGA data, we found that 30% of endometrial endometrioid carcinoma cases have beta-catenin mutations. We hypothesize that beta-catenin mutation may be associated with metastasis of endometrial endometrioid carcinoma. ER and PR expression was also compared to determine any changes after metastasis. Methods Retrospective institutional review of all endometrial endometrioid carcinoma (192 cases) between 2011 to 2018 was
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9

Sica, Gabriel, Patrick L. Wagner, Nassar Altorki, et al. "Immunohistochemical Expression of Estrogen and Progesterone Receptors in Primary Pulmonary Neuroendocrine Tumors." Archives of Pathology & Laboratory Medicine 132, no. 12 (2008): 1889–95. http://dx.doi.org/10.5858/132.12.1889.

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Abstract Context.—Lung and breast carcinomas are among the most prevalent cancers. Advances in cancer therapies can provide survival benefit and be potentially curative, even in metastatic disease. Due to the high prevalence of these carcinomas, it is not unusual to encounter lung nodule(s) in a patient with breast carcinoma, and distinguishing between primary and metastatic disease is critical for management/treatment. Occasionally neuroendocrine differentiation is present in breast carcinoma, making its distinction from pulmonary/nonpulmonary neuroendocrine tumors in the lung difficult. Obje
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10

Vias, Poorva, Ashish Saklani, Suman Singh, Anantika Thakur, and Era Sankhyan. "Perinephric and Ovarian Metastasis from Advanced Urothelial Carcinoma Bladder: Case Report of a Rare Dismal Disease." Asian Pacific Journal of Cancer Care 9, no. 1 (2024): 207–10. http://dx.doi.org/10.31557/apjcc.2024.9.1.207-210.

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Background: Metastatic urothelial carcinoma bladder at the time of diagnosis is a rare entity with lymph nodes, bones, lung and liver as common metastatic sites. Sometimes metastasis can be seen in various atypical sites.Case Presentation: Unusual location of metastasis can be seen in perinephric region, renal fascia and ovaries as seen in the described case. Primary urothelial carcinoma of ovary needs to be differentiated from the metastasis. There are no standard lines of management and the treatment needs to be individualised. Prognosis of metastatic urothelial carcinoma remains fatal with
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11

Wade, Zane K., John E. Shippey, Gregory A. Hamon, Robert L. Smoak, Pedram Argani, and William C. Allsbrook. "Collision Metastasis of Prostatic and Colonic Adenocarcinoma: Report of 2 Cases." Archives of Pathology & Laboratory Medicine 128, no. 3 (2004): 318–20. http://dx.doi.org/10.5858/2004-128-318-cmopac.

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Abstract Collision metastases of carcinomas in lymph nodes are rare. Carcinoma metastasizing to lymph nodes containing malignant lymphoma has also been reported. The literature contains 3 cases of collision metastasis of prostatic and urothelial carcinoma. To our knowledge, we report the first 2 cases of collision metastasis of prostatic and colonic adenocarcinoma, one involving a mesenteric lymph node and the other involving a perirectal lymph node, both from resections for colonic adenocarcinoma in patients with known metastatic prostatic carcinoma.
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12

Masuyama, Ayano, Atsushi Toshima, Asami Nakajima, and Masahiro Murakami. "Ultrasonographic Renal Subcapsular Thickening in Cats with Primary and Metastatic Carcinoma." Veterinary Sciences 11, no. 3 (2024): 134. http://dx.doi.org/10.3390/vetsci11030134.

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Ultrasonographic subcapsular thickening caused by renal neoplasia other than lymphoma has been previously reported in cats; however, detailed information is lacking. This study aims to describe ultrasonographic findings in renal subcapsular thickening and renal parenchyma in cats diagnosed or presumed with primary and metastatic carcinoma in the kidney. Ultrasound reports were retrospectively searched from 3 veterinary hospitals and 6 cats with 9 affected kidneys were included. Renal lesions were confirmed either cytologically or histopathologically as primary renal carcinoma with metastasis i
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13

Poosarla, Pavani, Prasad Bollineni, and Rama Rajasekhar S. "Clinicopathological Evaluation of Metastatic Carcinomas of Bone Marrow Presenting as Cytopenia." Annals of Pathology and Laboratory Medicine 8, no. 6 (2021): A147–151. http://dx.doi.org/10.21276/apalm.3056.

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Background – Metastatic carcinomas can involve bone marrow and may lead to subsequent marrow fibrosis and failure. The Bone marrow examination is important in patients diagnosed or patients on chemotherapy for cancer, who presented with peripheral cytopenia. The metastasis of bone marrow by these tumors is a sign of advanced stage of disease with poor prognosis.
 Methods – Our study is a retrospective study, in which we reviewed a total of 702 bone marrow procedures, out of which 118 bone marrow procedures done in patients with a diagnosis of cancer or patients on chemotherapy presented a
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14

Gholami, Shahzad, Mahin Bakhshi, Saede Atarbashi-Moghadam, Hassan Mir Mohammad Sadeghi, and Arezoo Rahimzamani. "Mandibular Metastasis of Silent Papillary Thyroid Carcinoma: A Rare Case Report with Review of the Literature." Case Reports in Dentistry 2020 (April 6, 2020): 1–6. http://dx.doi.org/10.1155/2020/8683465.

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Metastasis to the jaws is a rare event; however, it has great importance because it may be the only symptom of an undiagnosed underlying malignancy. Papillary thyroid carcinoma, the commonest histopathologic variant of thyroid cancer, has minimal potential for distant metastasis, and most reported metastatic thyroid carcinomas of the oral cavity have been follicular thyroid carcinoma. The aim of this article is to present a rare case of metastatic papillary thyroid carcinoma, which presented itself as a painless expansion in the anterior region of the mandible in a 56-year-old female, and to r
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15

Tickoo, Satish K., Anastassios G. Pittas, Michael Adler, et al. "Bone Metastases From Thyroid Carcinoma." Archives of Pathology & Laboratory Medicine 124, no. 10 (2000): 1440–47. http://dx.doi.org/10.5858/2000-124-1440-bmftc.

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Abstract Context.—Only limited information exists on the pathologic aspects of thyroid carcinomas with bone metastases, most large studies having concentrated mainly on their clinical features. Objective.—To study in detail the morphologic features of thyroid carcinomas with skeletal metastases. Design.—Seventy-nine cases of thyroid carcinoma with bone metastases treated at Memorial Sloan-Kettering Cancer Center, New York, NY, between 1964 and 1998 were investigated, with emphasis on the pathology of the primary and/or metastatic tumors and comparison of the morphologic features of the tumors
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16

Shanbhag, Nandan. "Metastatic colorectal carcinoma: Response to panitumumab." Journal of the Bahrain Medical Society 30, no. 1 (2018): 5–8. http://dx.doi.org/10.26715/jbms.1_01032018.

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Onak Kandemir, Nilufer, Figen Barut, Kıvanç Yılmaz, Husnu Tokgoz, Mubin Hosnuter, and Sukru Oguz Ozdamar. "Renal Cell Carcinoma Presenting with Cutaneous Metastasis: A Case Report." Case Reports in Medicine 2010 (2010): 1–5. http://dx.doi.org/10.1155/2010/913734.

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Renal cell carcinoma is the most common kidney tumor in adults. Cutaneous metastasis is a rare first symptom of the disease. This paper describes the diagnosis of a renal cell carcinoma that was indicated by cutaneous metastasis in the head and neck region, and considers the etiopathogenesis of such cases. A careful skin examination is important to detect cutaneous metastasis associated with renal cell carcinomas. Metastatic skin lesions in the head and neck region must be taken into consideration during a differential diagnosis.
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18

Martin, Jonathan, Maxwell A. Fung, and Lily Koo Lin. "Breast Cancer Metastasis Masquerading as the Great Masquerader: Sebaceous Cell Carcinoma." Case Reports in Oncology 10, no. 2 (2017): 485–88. http://dx.doi.org/10.1159/000477339.

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Objective: We describe the case of a patient with metastatic breast cancer who presented with eyelid margin thickening and madarosis more suggestive of sebaceous cell carcinoma than metastatic disease. Histopathology confirmed metastatic breast adenocarcinoma. Case Report: A 59-year-old woman with a known history of metastatic breast carcinoma actively enrolled in a clinical trial presented with a thickened right upper eyelid margin with madarosis and without ulceration. Although the possibility of metastasis was considered, a biopsy was performed to ensure the patient did not have a primary e
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19

Radojkovic, Milan, Jasmina Gligorijevic, Miroslav Stojanovic, Goran Stanojevic, and Ivan Ilic. "Laparotomy site implantation metastasis of carcinoma of the papilla of Vater." Scottish Medical Journal 62, no. 3 (2017): 119–21. http://dx.doi.org/10.1177/0036933017715958.

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Introduction Carcinomas of the papilla of Vater make up a heterogeneous group of tumours arising from different types of epithelium. Regional lymph nodes, liver and lungs are the primary sites of metastatic progression of these tumours. Case presentation We present a patient with an abdominal incision site metastasis of low-grade (mixed type) adenocarcinoma of the papilla of Vater one year after pylorus-preserving pancreaticoduodenectomy. Implantation metastasis of low-grade ampullary carcinoma in the laparotomy wound after open Whipple’s procedure is unusual. Conclusion Adjuvant chemoradiatio
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20

Gomez, Mariangela, Kerry Whitting, and Rana Naous. "Lobular breast carcinoma metastatic to the endometrium in a patient under tamoxifen therapy: A case report." SAGE Open Medical Case Reports 8 (January 2020): 2050313X2090720. http://dx.doi.org/10.1177/2050313x20907208.

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Metastatic carcinomas to the uterus are rare and usually originate from nearby gynecologic sites, most commonly from the ovaries. Among non-gynecologic origins, breast tumors are the most frequent primaries, predominantly the lobular carcinoma type. A 69-year-old postmenopausal woman diagnosed with lobular breast carcinoma 5 years ago, status post modified radical mastectomy, and currently on tamoxifen therapy presented with post-menopausal bleeding. Subsequent endometrial biopsy confirmed the diagnosis of metastatic lobular breast carcinoma to the endometrium. Breast carcinomas rarely metasta
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21

Mular, Shraddha Shankarrao, N. S. Mani, and Reena Bharadwaj. "Utility of immunohistochemistry with CK7 and CK20 in metastatic carcinoma." Indian Journal of Pathology and Oncology 11, no. 4 (2024): 364–70. https://doi.org/10.18231/j.ijpo.2024.079.

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: Carcinoma of unknown primary origin (CUP) is a diverse group of cancers that is defined by the presence of metastatic disease with no identified primary tumor at initial presentation. Simple epithelium of the various organs is the most common source of the cancer. These carcinomas usually metastasize to lymph nodes and various other organs. Diagnosis of metastatic carcinoma of unknown origin can be challenging and also critical for clinical and therapeutic decisions. Immunohistochemistry (IHC) using CK7 and CK20 is an essential ancillary tool for the identification and the differential diagn
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Kumar, Krishna, Jefferson R. Wilson, Qiuyan Li, and Ryan Phillipson. "Pituitary Carcinoma with Subependymal Spread." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 33, no. 3 (2006): 329–32. http://dx.doi.org/10.1017/s0317167100005254.

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Pituitary carcinomas have been reported to metastasize systemically and, less commonly, along the craniospinal axis. Metastatic lesions have been reported in the cerebral cortex, cerebellum, spinal cord, leptomeninges, cervical lymph nodes, liver, ovaries, and bone. The authors are unaware of any other examples of subependymal metastases of a pituitary carcinoma. We report such a case.Pituitary carcinoma is rare, accounting for roughly 0.2%1,3-5 of all pituitary tumors, with approximately 140 cases reported in the literature. These tumors are associated with a very high mortality, with 66% of
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23

Wang, Gang, Chen Zhou, Carlos F. Villamil, et al. "Metastatic Renal Cell Carcinoma to the Testis: A Clinicopathologic Analysis of Five Cases." Case Reports in Pathology 2020 (March 4, 2020): 1–6. http://dx.doi.org/10.1155/2020/9394680.

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The testicular spread of renal cell carcinoma is extremely rare. Five cases of renal cell carcinoma metastatic to the testis are described. The patients ranged from 45 to 81 years of age. Four of the five patients had known renal cell carcinoma. The time intervals between the partial and radical nephrectomies for the primary kidney tumors and the occurrence of testicular metastases ranged from 29 to 34 months. In one patient, the testicular mass was the initial presentation leading to a diagnosis of renal cell carcinoma. There were three ipsilateral metastases, one contralateral metastasis, an
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24

Shim, Hye-kyung, and Mi Ra Kim. "Comparative Analysis of Metastatic Thyroid Carcinoma versus Ectopic Thyroid Carcinoma in Lateral Neck Masses without Identifiable Primary Thyroid Carcinoma." Journal of Clinical Medicine 13, no. 19 (2024): 5819. http://dx.doi.org/10.3390/jcm13195819.

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Background/Objectives: Thyroid carcinoma, presenting as a lateral neck mass without an identifiable primary tumor within the thyroid, poses a diagnostic challenge. This comparative analysis aimed to explore the differences between metastatic thyroid carcinoma and ectopic thyroid carcinoma, as both present with a lateral neck mass without evidence of primary thyroid carcinoma. Methods: Searches were conducted for studies on thyroid carcinoma in the lateral neck without evidence of primary thyroid carcinoma. A total of 39 patients were identified from 32 reported studies. Results: Metastatic and
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25

Lyon, Priscilla R. P., Sean Trevathan, Rudranath Talukdar, Dominic D. Nguyen, Christopher M. McPhaul, and Debby Rampisela. "A Rare Case of Metastatic Hepatocellular Carcinoma to the Hard Palate." Journal of Investigative Medicine High Impact Case Reports 10 (January 2022): 232470962211339. http://dx.doi.org/10.1177/23247096221133989.

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Extrahepatic metastasis of hepatocellular carcinoma (HCC) to the head and neck is unusual, especially the oral cavity/maxillofacial region. Metastatic HCC to the hard palate, however, is particularly rare. The most common site of HCC metastasis is the lung, followed by lymph nodes, bone, and adrenal gland. Importantly, oral cavity metastatic HCC may be misdiagnosed as a primary malignancy, such as a salivary gland carcinoma. In this article, we describe a young woman with metastatic HCC to the hard palate that was initially diagnosed as an acinic cell carcinoma.
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Slim, Ihsen, Aida Mhiri, Imène Meddeb, Aida Goucha, Saïd Gritli, and Mohamed Faouzi Ben Slimene. "Malar Bone Metastasis Revealing a Papillary Thyroid Carcinoma." Case Reports in Otolaryngology 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/795686.

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Papillary thyroid carcinoma is the most common form of differentiated thyroid carcinoma. It is generally confined to the neck with or without spread to regional lymph nodes. Metastatic thyroid carcinomas are uncommon and mainly include lung and bone. Metastases involving oral and maxillofacial region are extremely rare. We described a case of malar metastasis revealing a follicular variant of papillary thyroid carcinoma, presenting with pain and swelling of the left cheek in a 67-years-old female patient with an unspecified histological left lobo-isthmectomy medical history. To our knowledge,
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Yucel, Emre A., Tayfun Demirel, Misten Demiryont, Unal Egeli, and Kemal Deger. "An unusual metastatic site of laryngeal carcinoma: scapular muscles." Journal of Laryngology & Otology 117, no. 1 (2003): 85–87. http://dx.doi.org/10.1258/002221503321046757.

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It is well known that in advanced cervical metastatic disease of head and neck squamous cell carcinoma, the incidence of distant metastasis is high. A case of distant metastasis to the scapular muscles from an uncontrolled cervical metastasis of laryngeal carcinoma is presented. Other unusual metastatic sites are reviewed and the possible mechanism of the spread is discussed.
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Zhang, Li, Po Ding, Hongcheng Lv, et al. "Number of Polyploid Giant Cancer Cells and Expression of EZH2 Are Associated with VM Formation and Tumor Grade in Human Ovarian Tumor." BioMed Research International 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/903542.

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To investigate the associations among the number of polyploid giant cancer cells (PGCCs) and vasculogenic mimicry (VM), EZH2 expression, and serous ovarian tumor grade, a total of 80 paraffin-embedded serous ovarian tumor samples including 21 cases of primary carcinoma and their metastatic tumors, 26 cases of primary carcinoma without metastasis, and 12 cases of serous borderline cystadenoma were analyzed. PGCCs and VM were detected in human serous ovarian tumor. The metastatic foci of ovarian carcinoma had the highest number of PGCCs and VM. The number of PGCCs and VM increased with the grade
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Yeh, Chun-Nan, Cheng-Hung Lin, and Miin-Fu Chen. "Clinical and Ultrasonographic Characteristics of Breast Metastases from Extramammary Malignancies." American Surgeon 70, no. 4 (2004): 287–90. http://dx.doi.org/10.1177/000313480407000402.

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Breast metastases from extramammary malignancies are uncommon, constituting about 2 per cent of all breast tumors. Breast metastasis may be confused with primary benign or malignant neoplasm of the breast. An accurate diagnosis of breast metastasis is important because the treatment and outcome of primary and secondary malignancies of the breast are completely different. The clinical features of 15 patients with breast metastases from extramammary malignancies, excluding lymphoma, between 1982 and 2001 were retrospectively reviewed. There were 2 male and 13 female patients, with ages ranging f
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Lenzi, R., M. Marchetti, and L. Muscatello. "Incidental nodal metastasis of differentiated thyroid carcinoma in neck dissection specimens from head and neck cancer patients." Journal of Laryngology & Otology 131, no. 4 (2017): 368–71. http://dx.doi.org/10.1017/s002221511700024x.

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AbstractBackground:Occult differentiated thyroid carcinomas are not uncommon. The initial presentation of a thyroid carcinoma is often detection of a metastatic cervical lymph node.Methods:A retrospective review was performed of the medical records of 304 patients who underwent neck dissection between 1996 and 2008 for squamous cell carcinoma of the head and neck.Results:Ten patients (3.3 per cent) had nodal metastasis originating from papillary thyroid cancer. All of these patients underwent thyroidectomy and post-operative 131iodine radiometabolic therapy. No patient developed a thyroid tumo
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Manav, Alper Nesip, Ercan Kazan, Mehmet Şirin Ertek, Akın Soner Amasyalı, Nil Çulhacı, and Haluk Erol. "A Rare Cause of Testicular Metastasis: Upper Tract Urothelial Carcinoma." Case Reports in Urology 2014 (2014): 1–3. http://dx.doi.org/10.1155/2014/759858.

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Metastatic testicular cancers are rare. Primary tumor sources are prostate, lung, and gastrointestinal tract for metastatic testicular cancers. Metastasis of urothelial carcinoma (UC) to the testis is extremely rare. Two-thirds of upper tract urothelial carcinoma (UTUC) is of invasive stage at diagnosis and metastatic sites are the pelvic lymph nodes, liver, lung, and bone. We report a rare case of metastatic UTUC to the testis which has not been reported before, except one case in the literature. Testicular metastasis of UC should be considered in patients with hematuria and testicular swelli
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32

Shehab, Zaid, Sylvana Desousa, and Ahmes L. Pahor. "Metastasis in tongue from carcinoma of bronchus: a case report." Journal of Laryngology & Otology 108, no. 12 (1994): 1099–101. http://dx.doi.org/10.1017/s0022215100129019.

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AbstractA case of carcinoma of the lung with a metastasis on the tongue is presented. The case is of interest because, although primary carcinomas of the tongue are fairly common accounting for 50 per cent of all oral carcinomas, metastatic tumour represents only one per cent of all malignant tumours of the oral cavity and of these only 0.2 per cent metastasize to the tongue.
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Laga, Alvaro C., Inga Marie Schaefer, Lynette M. Sholl, Christopher A. French, and John Hanna. "Metastatic Basal Cell Carcinoma." American Journal of Clinical Pathology 152, no. 6 (2019): 706–17. http://dx.doi.org/10.1093/ajcp/aqz089.

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Abstract Objectives Diagnosis of metastatic basal cell carcinoma (BCC) remains challenging, in part due to its rarity. With the advent of molecularly targeted therapies, recognition of this entity is more important than ever. Methods We identified 11 cases of metastatic BCC over a 13-year period. We analyzed these tumors in conjunction with their respective primary tumors by histomorphologic, immunohistochemical, and molecular genetic analyses. Results We identified three morphologic patterns of metastasis in BCC. The most common (seven cases) was characterized by completely typical features o
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Chapagain, U., S. Neupane, S. Tuladhar, S. Pradhananga, RB Basnet, and S. Regmi. "Prostatic cancer with metastasis to the testis – A case report." Journal of Pathology of Nepal 5, no. 9 (2015): 784–86. http://dx.doi.org/10.3126/jpn.v5i9.13792.

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Metastatic carcinoma to the testis is very rare.The incidence of secondary testicular tumors ranges from 0.02 to 2.5% among autopsies ingeneral. Despite the high incidence of prostatic adenocarcinoma and its ability for wide dissemination, metastatic cancer to the testis is a rare phenomenon of prostate carcinoma with only 80 cases reported in the literature.It is diagnosed in autopsies or incidentally, following therapeutic orchiectomies in moreadvanced stages of the disease.Ours is the very first case of prostatic carcinoma metastasizing to the testis, being reported from our country. We are
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35

Davidson, N. G. P., and A. Wilson. "Tongue metastasis from carcinoma of the rectum." Journal of Laryngology & Otology 103, no. 3 (1989): 322–23. http://dx.doi.org/10.1017/s0022215100108825.

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AbstractA case report of a patient with carcinoma of the rectum with metastasis to the tongue clinically mimicking a primary tongue neoplasm is described. The patient presented with an ulcer in the tongue three years after undergoing an anterior resection for a Dukes C carcinoma of the rectum. Other asymptomatic metastatic lesions were discovered only after the histology report suggested that the tongue ulcer biopsy was metastatic in origin. Metastatic tumour to the tongue is extremely rare and often occurs at a late stage, when there is disseminated disease. We are not aware of any reported c
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36

Kern, Michael, Gabriel Lee, Peter Robbins, Michael Bynevelt, and Peter Watson. "Intracranial metastatic parathyroid carcinoma." Journal of Neurosurgery 101, no. 6 (2004): 1065–69. http://dx.doi.org/10.3171/jns.2004.101.6.1065.

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✓ Parathyroid carcinoma (PTC) is a rare pathological entity, with fewer than 400 reported cases. Intracranial metastasis of a PTC is exceptional; only five other cases have been identified in the English literature. The authors present a unique case of a patient with a solitary intracerebral metastasis of a PTC in an individual presumed to have hereditary hyperparathyroidism who had concomitant papillary and follicular carcinomas of the thyroid. The literature relevant to the management of these rare lesions is reviewed and discussed.
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37

Bergeron, Anthony, Isabelle Desmoulins, Francoise Beltjens, et al. "An exceptional metaplastic lobular breast carcinoma diagnosed through exome sequencing." Journal of Clinical Pathology 73, no. 9 (2020): 597–601. http://dx.doi.org/10.1136/jclinpath-2019-205783.

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Metaplastic breast carcinoma is a rare subtype of breast cancer. This subtype is mostly found in association with poorly differentiated ductal breast carcinomas and rarely with other breast carcinoma types. We report the case of a 69-year-old woman with an exceptional invasive lobular breast carcinoma associated with metaplastic squamous cell bone metastasis occurring 2 years after the initial breast cancer diagnosis. Whole-exome sequencing and subsequent immunohistochemistry of the lesions were used to link the squamous cell bone metastasis of unknown origin to the primary breast carcinoma in
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38

Atjo, Sriwati, Uleng Bahrun, and Hardjoeno Hardjoeno. "ANALISIS KADAR SERUM FERITIN DI KARSINOMA PAYUDARA (Analysis of Ferritin Levels in Carcinoma Mammae)." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 22, no. 1 (2018): 34. http://dx.doi.org/10.24293/ijcpml.v22i1.1219.

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Carcinoma Mammae is a malignant disease originating from mammary parenchyma, and the second largest cause of death inthe world. Ferritin is a marker of neoplasia, which levels are increased in non-metastatic carcinoma mammae and more increased inmetastatic carcinoma mammae. This cross sectional study was conducted during June 2012 in carcinoma mammae patients of theWahidin Sudirohusodo Hospital, Ibnu Sina Hospital and Labuang Baji Hospital in Makassar. The aim of this study was to know theserum ferritin levels in metastatic and non-metastatic carcinoma mammae. In this study, 56 samples were ob
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39

Karimi, S. S., and M. Braniecki. "An Uncommon Case of Colonic Neuroendocrine Carcinoma with Scalp Metastasis." American Journal of Clinical Pathology 156, Supplement_1 (2021): S48. http://dx.doi.org/10.1093/ajcp/aqab191.097.

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Abstract Introduction/Objective Neuroendocrine neoplasms of the colon account for <1% of all colorectal malignancies. While visceral metastasis of neuroendocrine neoplasms is commonly observed, cutaneous distant metastasis has infrequently been reported and correlates with an advance stage and progression of disease. To our knowledge, there have been only 10 cases of neuroendocrine neoplasms with metastasis to the scalp reported in the literature. Herein, we report an unusual case of colonic neuroendocrine carcinoma with scalp metastasis, that can be microscopically indistinguishable fr
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40

Kadin, M. "Metastatic Carcinoma." ASH Image Bank 2003, no. 0507 (2003): 100703. http://dx.doi.org/10.1182/ashimagebank-2003-100703.

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41

Yi, Wook, Bo Hyun Kim, Jeong Mi Kim, and Yong Ki Kim. "Metastatic Clear Cell Renal Carcinoma with Benign Ultrasonographic Findings in the Thyroid Gland." Clinical Ultrasound 6, no. 2 (2021): 63–66. http://dx.doi.org/10.18525/cu.2021.6.2.63.

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Metastasis to the thyroid gland is rare, and the incidence of thyroid metastasis is from 1.4% to 3% for all thyroid malignancies. The most common metastatic malignancy to the thyroid gland is renal cell carcinoma. Ultrasonography is useful to assess the malignancy risk of thyroid nodules, and the ultrasonographic features of metastatic renal cell carcinoma in the thyroid gland are hypoechoic solid nodules with increased vascularity. Here, we report a case of metastatic clear cell renal carcinoma with benign ultrasonographic features and fine-needle aspiration cytology in the thyroid gland. A 7
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42

Washino, S., M. Hirai, A. Matsuzaki, and Y. Kobayashi. "Long-Term Survival after Adrenalectomy for Asynchronous Metastasis of Bladder Cancer to the Bilateral Adrenal Glands." Case Reports in Urology 2012 (2012): 1–3. http://dx.doi.org/10.1155/2012/425230.

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Isolated adrenal metastasis of bladder cancer, particularly the bilateral, is quite rare. Systemic chemotherapy is the treatment of choice for metastatic urothelial carcinoma. However, despite initially promising response rates of approximately 45%–71%, most tumors eventually show progression, and the median survival time following chemotherapy regimen is approximately 14-15 months. Recently, favorable results of surgery for metastatic urothelial carcinoma have been reported. Here, we report a rare case of asynchronous metastasis of bladder cancer to the bilateral adrenal glands with long-term
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43

Gruver, Aaron M., Mahul B. Amin, Daniel J. Luthringer, et al. "Selective Immunohistochemical Markers to Distinguish Between Metastatic High-Grade Urothelial Carcinoma and Primary Poorly Differentiated Invasive Squamous Cell Carcinoma of the Lung." Archives of Pathology & Laboratory Medicine 136, no. 11 (2012): 1339–46. http://dx.doi.org/10.5858/arpa.2011-0575-oa.

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Context.—Distinction between primary lung carcinomas and metastases from other sites, especially the urinary tract, is a common diagnostic dilemma. As urothelial carcinomas can demonstrate a broad range of morphology and frequently demonstrate squamous differentiation, discerning metastatic urothelial carcinoma to the lung from primary pulmonary squamous cell carcinoma can be challenging. Objective.—To investigate immunostains that may aid in the distinction of urothelial carcinoma metastatic to the lung. Design.—Staining patterns of 14 markers in primary urothelial carcinoma of the bladder an
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44

Deng, Yu-Wei, Yi-Wen Li, Wen-Jing Hao, and Dan Lu. "A Clinical Observation of Thymic Epithelial Tumor Metastatic to Breast." Breast Care 13, no. 2 (2018): 133–36. http://dx.doi.org/10.1159/000486028.

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Background: Thymic carcinoma is prone to early metastasis and invasion, while its metastasis to the breast is particularly unique. Case Report: We describe a case of thymic epithelial tumor metastatic to the breast fulfilling clinical diagnostic criteria. A 47-year-old female patient diagnosed with stage IV thymic carcinoma and previously treated with chemoradiation was diagnosed with metastatic breast cancer during a periodic review. Color Doppler ultrasonography showed a low-echo real occupancy in the breast. Pathological examination of the breast mass confirmed the diagnosis of thymic carci
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45

Conlin, Phillip A., Jose Luis Mira, Suzanne C. Graham, Kim Sutker Kaye, and Joehassin Cordero. "Ceruminous Gland Adenoid Cystic Carcinoma With Contralateral Metastasis to the Brain." Archives of Pathology & Laboratory Medicine 126, no. 1 (2002): 87–89. http://dx.doi.org/10.5858/2002-126-0087-cgaccw.

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Abstract We present the case of a 38-year-old man with an adenoid cystic carcinoma originating from the ceruminous glands of the external ear canal. The patient subsequently presented with a contralateral brain mass that was also diagnosed as adenoid cystic carcinoma. To our knowledge, contralateral metastasis to the brain of a patient with an adenoid cystic carcinoma of the ceruminous glands has not been reported previously. This rare neoplasm should be considered in the differential diagnosis of poorly differentiated carcinomas metastatic to the central nervous system in patients with occult
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46

Galili, Yehuda, Meghan Lytle, Jonathan Bartolomei, et al. "Clear-Cell Carcinoma of the Ovary with Bilateral Breast Metastases." Case Reports in Oncological Medicine 2019 (April 28, 2019): 1–4. http://dx.doi.org/10.1155/2019/8013913.

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Ovarian clear-cell carcinoma is an uncommon subtype of epithelial ovarian carcinoma. It carries a generally poor prognosis because of its resistance to standard treatment and metastatic spread to vital organs. Metastasis to the breast is rare and bilateral breast metastasis is unreported. A 61-year-old white female with a 5-year status poststandard therapy for stage IC clear-cell ovarian carcinoma presented with widespread metastasis. Tissue analysis revealed ovarian cancer metastasis to the breasts bilaterally. Clinical awareness of this metastatic potential is important when staging and deve
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47

Stevens, Todd M., Alan T. Richards, Chhanda Bewtra, and Poonam Sharma. "Tumors Metastatic to Thyroid Neoplasms: A Case Report and Review of the Literature." Pathology Research International 2011 (March 31, 2011): 1–5. http://dx.doi.org/10.4061/2011/238693.

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Metastasis into a thyroid neoplasm—tumor-to-tumor metastasis—is exceedingly rare. We describe the 28th documented case of a tumor metastatic to a thyroid neoplasm and review the literature on tumor-to-tumor metastasis involving a thyroid neoplasm as recipient. All cases showed a recipient thyroid neoplasm with an abrupt transition to a morphologically distinct neoplasm. Metastasis into primary thyroid neoplasm was synchronous in 33% of cases and metachronous in 67%. Follicular adenoma was the most common recipient thyroid neoplasm overall (16/28), and papillary thyroid carcinoma was the most c
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48

Gill, Ryan, Richard J. O'Donnell, and Andrew Horvai. "Utility of Immunohistochemistry for Endothelial Markers in Distinguishing Epithelioid Hemangioendothelioma From Carcinoma Metastatic to Bone." Archives of Pathology & Laboratory Medicine 133, no. 6 (2009): 967–72. http://dx.doi.org/10.5858/133.6.967.

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Abstract Context.—Epithelioid hemangioendothelioma (EHE) is a rare vascular neoplasm of intermediate malignancy. Epithelioid hemangioendothelioma often presents a difficult diagnostic problem, especially in bone, because the epithelioid morphology and radiographic features raise the possibility of metastatic carcinoma. The current trend of small biopsies obtained with computed tomography–guided techniques exacerbates the problem. The markedly different treatment for EHE and metastatic carcinoma underscores the need for specific markers that can differentiate between these 2 entities. Objective
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49

Kundu, Eynon-Lewis, and Radcliffe. "Extensive metastatic renal cell carcinoma presenting as facial nerve palsy." Journal of Laryngology & Otology 115, no. 6 (2001): 488–90. http://dx.doi.org/10.1258/0022215011908009.

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Metastatic lesions of the parotid gland are well described in the literature. Metastatic spread to the parotid from renal cell carcinoma is rare. We present the only reported case of facial nerve palsy caused by a metastasis to the parotid from a renal cell carcinoma.
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Mandell-Brown, Mark, Jonas T. Johnson, Bruce S. Rabin, Ellen Hamill, and Robin L. Wagner. "Neck Node Immunoreactivity in Head and Neck Carcinoma." Otolaryngology–Head and Neck Surgery 95, no. 4 (1986): 500–506. http://dx.doi.org/10.1177/019459988609500414.

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T-lymphocyte subpopulations were quantitated in lymph nodes that contained metastatic tumor—or no metastasis—from patients who had squamous cell carcinoma of the upper aerodigestive tract. In addition, the lymphocyte subpopulations in peripheral blood were quantitated. The content of prostaglandin E2 within each node that was evaluated was also determined. Lymph nodes containing metastatic tumor had significantly higher helper/suppressor ratio than lymph nodes that were not involved. Quantification of the T-lymphocyte subpopulations in peripheral blood did not indicate the presence of metastat
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