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1

VINOPAL, R. T. "Microbial Metabolism." Science 239, no. 4839 (January 29, 1988): 513.2–514. http://dx.doi.org/10.1126/science.239.4839.513.

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Downs, Diana M. "Understanding Microbial Metabolism." Annual Review of Microbiology 60, no. 1 (October 2006): 533–59. http://dx.doi.org/10.1146/annurev.micro.60.080805.142308.

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ARNAUD, CELIA. "VIEWING MICROBIAL METABOLISM." Chemical & Engineering News 85, no. 38 (September 17, 2007): 11. http://dx.doi.org/10.1021/cen-v085n038.p011.

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Wackett, Lawrence P. "Microbial metabolism prediction." Environmental Microbiology Reports 2, no. 1 (February 8, 2010): 217–18. http://dx.doi.org/10.1111/j.1758-2229.2010.00144.x.

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Hahn-Hägerdal, Bärbel, and Neville Pamment. "Microbial Pentose Metabolism." Applied Biochemistry and Biotechnology 116, no. 1-3 (2004): 1207–10. http://dx.doi.org/10.1385/abab:116:1-3:1207.

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6

Wackett, Lawrence P. "Microbial community metabolism." Environmental Microbiology Reports 5, no. 2 (March 5, 2013): 333–34. http://dx.doi.org/10.1111/1758-2229.12041.

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Wackett, Lawrence P. "Microbial community metabolism." Environmental Microbiology Reports 15, no. 3 (May 5, 2023): 240–41. http://dx.doi.org/10.1111/1758-2229.13161.

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Rajini, K. S., P. Aparna, Ch Sasikala, and Ch V. Ramana. "Microbial metabolism of pyrazines." Critical Reviews in Microbiology 37, no. 2 (April 11, 2011): 99–112. http://dx.doi.org/10.3109/1040841x.2010.512267.

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Chubukov, Victor, Luca Gerosa, Karl Kochanowski, and Uwe Sauer. "Coordination of microbial metabolism." Nature Reviews Microbiology 12, no. 5 (March 24, 2014): 327–40. http://dx.doi.org/10.1038/nrmicro3238.

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Ash, Caroline. "Microbial entrainment of metabolism." Science 365, no. 6460 (September 26, 2019): 1414.10–1416. http://dx.doi.org/10.1126/science.365.6460.1414-j.

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Nakamura, T. "Microbial Manipulation of Metabolism." Science Translational Medicine 4, no. 148 (August 22, 2012): 148ec153. http://dx.doi.org/10.1126/scitranslmed.3004777.

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12

Orabi, K. "Microbial metabolism of artemisitene." Phytochemistry 51, no. 2 (May 1999): 257–61. http://dx.doi.org/10.1016/s0031-9422(98)00770-5.

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13

Rao, AS. "Terminology in microbial metabolism." Biochemical Education 24, no. 1 (January 1996): 61–62. http://dx.doi.org/10.1016/s0307-4412(96)80011-2.

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14

Howland, John L. "Microbial physiology and metabolism." Biochemical Education 23, no. 2 (April 1995): 106. http://dx.doi.org/10.1016/0307-4412(95)90661-4.

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15

Cerniglia, Carl E., Daniel W. Kelly, James P. Freeman, and Dwight W. Miller. "Microbial metabolism of pyrene." Chemico-Biological Interactions 57, no. 2 (February 1986): 203–16. http://dx.doi.org/10.1016/0009-2797(86)90038-4.

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16

Sonnleitner, B. "Quantitation of microbial metabolism." Antonie van Leeuwenhoek 60, no. 3-4 (1991): 133–43. http://dx.doi.org/10.1007/bf00430361.

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17

Stoker, C. R., P. J. Boston, R. L. Mancinelli, W. Segal, B. N. Khare, and C. Sagan. "Microbial metabolism of tholin." Icarus 85, no. 1 (May 1990): 241–56. http://dx.doi.org/10.1016/0019-1035(90)90114-o.

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18

Alfred, Jane. "Microbial genomes to metabolism." Nature Reviews Genetics 3, no. 10 (October 2002): 733. http://dx.doi.org/10.1038/nrg922.

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19

Dong, Mei, Xizhi Feng, Ben-Xiang Wang, Takashi Ikejima, and Li-Jun Wu. "Microbial Metabolism of Pseudoprotodioscin." Planta Medica 70, no. 7 (July 2004): 637–41. http://dx.doi.org/10.1055/s-2004-827187.

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20

Mikell, Julie Rakel, Wimal Herath, and Ikhlas Ahmad Khan. "Microbial Metabolism. Part 12." Chemical and Pharmaceutical Bulletin 59, no. 6 (2011): 692–97. http://dx.doi.org/10.1248/cpb.59.692.

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21

Heider, Johann, and Georg Fuchs. "Microbial Anaerobic Aromatic Metabolism." Anaerobe 3, no. 1 (February 1997): 1–22. http://dx.doi.org/10.1006/anae.1997.0073.

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22

McChesney, J., and S. Kouzi. "Microbial Models of Mammalian Metabolism: Sclareol Metabolism." Planta Medica 56, no. 06 (December 1990): 693. http://dx.doi.org/10.1055/s-2006-961374.

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23

Fouillaud, Mireille, and Laurent Dufossé. "Microbial Secondary Metabolism and Biotechnology." Microorganisms 10, no. 1 (January 7, 2022): 123. http://dx.doi.org/10.3390/microorganisms10010123.

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In recent decades scientific research has demonstrated that the microbial world is infinitely richer and more surprising than we could have imagined. Every day, new molecules produced by microorganisms are discovered, and their incredible diversity has not yet delivered all of its messages. The current challenge of research is to select from the wide variety of characterized microorganisms and compounds, those which could provide rapid answers to crucial questions about human or animal health or more generally relating to society’s demands for medicine, pharmacology, nutrition or everyday well-being.
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24

Wintermute, Edwin H., and Pamela A. Silver. "Emergent cooperation in microbial metabolism." Molecular Systems Biology 6, no. 1 (January 2010): 407. http://dx.doi.org/10.1038/msb.2010.66.

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Crunkhorn, Sarah. "Microbial metabolite predicts human metabolism." Nature Reviews Drug Discovery 8, no. 10 (October 2009): 772–73. http://dx.doi.org/10.1038/nrd3008.

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26

Schuetz, R., N. Zamboni, M. Zampieri, M. Heinemann, and U. Sauer. "Multidimensional Optimality of Microbial Metabolism." Science 336, no. 6081 (May 3, 2012): 601–4. http://dx.doi.org/10.1126/science.1216882.

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27

VanHook, Annalisa M. "Microbial metabolites shape lipid metabolism." Science Signaling 13, no. 627 (April 14, 2020): eabc1552. http://dx.doi.org/10.1126/scisignal.abc1552.

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28

Ensign, Scott A. "Microbial Metabolism of Aliphatic Alkenes†." Biochemistry 40, no. 20 (May 2001): 5845–53. http://dx.doi.org/10.1021/bi015523d.

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29

Kochanowski, Karl, Uwe Sauer, and Elad Noor. "Posttranslational regulation of microbial metabolism." Current Opinion in Microbiology 27 (October 2015): 10–17. http://dx.doi.org/10.1016/j.mib.2015.05.007.

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30

Heinemann, Matthias, and Uwe Sauer. "Systems biology of microbial metabolism." Current Opinion in Microbiology 13, no. 3 (June 2010): 337–43. http://dx.doi.org/10.1016/j.mib.2010.02.005.

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31

Kelly, D. P., and J. C. Murrell. "Microbial metabolism of methanesulfonic acid." Archives of Microbiology 172, no. 6 (November 15, 1999): 341–48. http://dx.doi.org/10.1007/s002030050770.

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32

Codd, G. A. "Environmental regulation of microbial metabolism." Endeavour 10, no. 1 (January 1986): 52. http://dx.doi.org/10.1016/0160-9327(86)90063-3.

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33

McArthur, George H., and Stephen S. Fong. "Toward Engineering Synthetic Microbial Metabolism." Journal of Biomedicine and Biotechnology 2010 (2010): 1–10. http://dx.doi.org/10.1155/2010/459760.

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The generation of well-characterized parts and the formulation of biological design principles in synthetic biology are laying the foundation for more complex and advanced microbial metabolic engineering. Improvements inde novoDNA synthesis and codon-optimization alone are already contributing to the manufacturing of pathway enzymes with improved or novel function. Further development of analytical and computer-aided design tools should accelerate the forward engineering of precisely regulated synthetic pathways by providing a standard framework for the predictable design of biological systems from well-characterized parts. In this review we discuss the current state of synthetic biology within a four-stage framework (design, modeling, synthesis, analysis) and highlight areas requiring further advancement to facilitate true engineering of synthetic microbial metabolism.
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34

Zhan, Ji-Xun, Yuan-Xing Zhang, Hong-Zhu Guo, Jian Han, Li-Li Ning, and De-An Guo. "Microbial Metabolism of Artemisinin byMucorpolymorphosporusandAspergillusniger." Journal of Natural Products 65, no. 11 (November 2002): 1693–95. http://dx.doi.org/10.1021/np020113r.

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35

Negre, M., M. Gennari, V. Andreoni, R. Ambrosoli, and L. Celi. "Microbial metabolism of fluazifop-butyl." Journal of Environmental Science and Health, Part B 28, no. 5 (October 1993): 545–76. http://dx.doi.org/10.1080/03601239309372841.

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36

Herath, Wimal, Daneel Ferreira, Julie Rakel Mikell, and Ikhlas Ahmad Khan. "Microbial Metabolism. Part 5. Dihydrokawain." CHEMICAL & PHARMACEUTICAL BULLETIN 52, no. 11 (2004): 1372–74. http://dx.doi.org/10.1248/cpb.52.1372.

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37

Herath, Wimal, Daneel Ferreira, and Ikhlas A. Khan. "Microbial metabolism. Part 7: Curcumin." Natural Product Research 21, no. 5 (May 2007): 444–50. http://dx.doi.org/10.1080/14786410601082144.

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38

Klitgord, Niels, and Daniel Segrè. "Ecosystems biology of microbial metabolism." Current Opinion in Biotechnology 22, no. 4 (August 2011): 541–46. http://dx.doi.org/10.1016/j.copbio.2011.04.018.

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39

Gennari, Mara, Marco Vincenti, Michèle Nègre, and Roberto Ambrosoli. "Microbial metabolism of fenoxaprop-ethyl." Pesticide Science 44, no. 3 (July 1995): 299–303. http://dx.doi.org/10.1002/ps.2780440314.

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Martínez-Espinosa, Rosa María, and Carmen Pire. "Molecular Advances in Microbial Metabolism." International Journal of Molecular Sciences 24, no. 9 (April 28, 2023): 8015. http://dx.doi.org/10.3390/ijms24098015.

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Climate change, global pollution due to plastics, greenhouse gasses, or heavy metals among other pollutants, as well as limited natural sources due to unsustainable lifestyles and consumption patterns, are revealing the need for more research to understand ecosystems, biodiversity, and global concerns from the microscale to the macroscale [...]
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41

Bidkhori, Gholamreza, and Saeed Shoaie. "MIGRENE: The Toolbox for Microbial and Individualized GEMs, Reactobiome and Community Network Modelling." Metabolites 14, no. 3 (February 21, 2024): 132. http://dx.doi.org/10.3390/metabo14030132.

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Understanding microbial metabolism is crucial for evaluating shifts in human host–microbiome interactions during periods of health and disease. However, the primary hurdle in the realm of constraint-based modeling and genome-scale metabolic models (GEMs) pertaining to host–microbiome interactions lays in the efficient utilization of metagenomic data for constructing GEMs that encompass unexplored and uncharacterized genomes. Challenges persist in effectively employing metagenomic data to address individualized microbial metabolisms to investigate host–microbiome interactions. To tackle this issue, we have created a computational framework designed for personalized microbiome metabolisms. This framework takes into account factors such as microbiome composition, metagenomic species profiles and microbial gene catalogues. Subsequently, it generates GEMs at the microbial level and individualized microbiome metabolisms, including reaction richness, reaction abundance, reactobiome, individualized reaction set enrichment (iRSE), and community models. Using the toolbox, our findings revealed a significant reduction in both reaction richness and GEM richness in individuals with liver cirrhosis. The study highlighted a potential link between the gut microbiota and liver cirrhosis, i.e., increased level of LPS, ammonia production and tyrosine metabolism on liver cirrhosis, emphasizing the importance of microbiome-related factors in liver health.
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42

Kuo, Jimmy, Daniel Liu, and Chorng-Horng Lin. "Functional Prediction of Microbial Communities in Sediment Microbial Fuel Cells." Bioengineering 10, no. 2 (February 3, 2023): 199. http://dx.doi.org/10.3390/bioengineering10020199.

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Sediment microbial fuel cells (MFCs) were developed in which the complex substrates present in the sediment could be oxidized by microbes for electron production. In this study, the functional prediction of microbial communities of anode-associated soils in sediment MFCs was investigated based on 16S rRNA genes. Four computational approaches, including BugBase, Functional Annotation of Prokaryotic Taxa (FAPROTAX), the Phylogenetic Investigation of Communities by Reconstruction of Unobserved States (PICRUSt2), and Tax4Fun2, were applied. A total of 67, 9, 37, and 38 functional features were statistically significant. Among these functional groups, the function related to the generation of precursor metabolites and energy was the only one included in all four computational methods, and the sum total of the proportion was 93.54%. The metabolism of cofactor, carrier, and vitamin biosynthesis was included in the three methods, and the sum total of the proportion was 29.94%. The results suggested that the microbial communities usually contribute to energy metabolism, or the metabolism of cofactor, carrier, and vitamin biosynthesis might reveal the functional status in the anode of sediment MFCs.
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43

Jiang, Shao Yan, Wen Xing Wang, and Xiang Xin Xue. "Diversity in Microbial Carbon Metabolism of the Oil Shale at the Western Open Group in Fushun Basin." Advanced Materials Research 864-867 (December 2013): 140–44. http://dx.doi.org/10.4028/www.scientific.net/amr.864-867.140.

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The oil shale in the Western Fushun Basin as research object was investigated by Biolog-ECO to explore the functional diversity in microbial carbon metabolism of the oil shale. The process of Biolog-ECO was that, first determining the microbial community level physiological patterns during the 7 consecutive days by ECO microplate, then analyzing the differences in microbial metabolism of different types of carbon. The results showed that there were significant differences of the rate and extent in different types of carbon metabolism. The metabolism of carbohydrates, amino acids and amines carbon were significantly better than other carbon sources in all microbial communities, while the metabolism of acid metabolite was poor. Through continuous multi-point measuring the diversity index of Shannon-wiener, Simpson and McIntosh, overall, the microbial diversity was good, but with the time passing, the functional diversity of the carbon metabolism decreased.
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44

Zeng, Xuan, Yuying Zheng, Yan He, Jiashuo Zhang, Wei Peng, and Weiwei Su. "Microbial Metabolism of Naringin and the Impact on Antioxidant Capacity." Nutrients 14, no. 18 (September 13, 2022): 3765. http://dx.doi.org/10.3390/nu14183765.

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Naringin is a dietary flavonoid glycoside with broad bioactivities, and it has been found to undergo extensive microbial metabolism in human gut. Microbial metabolites are believed to play an important role in the overall bioactivity of naringin. However, knowledge is scarce about its microbial metabolism in laboratory rats, which are the most commonly used animal model for naringin-related biomedical studies. Herein, we profiled the microbial metabolism of naringin in rat by an in vitro anaerobic fermentation combined with LC-MS/MS methods. A total of 35 microbial metabolites were identified, and corresponding metabolic pathways were proposed. Naringin and its metabolites were further quantified in fermentation samples. Rhoifolin, neoeriocitrin, neohesperidin, naringenin, methylated naringin, and hydroxylated naringin were detected as the primary microbial metabolites. Moreover, antioxidant capacity assays suggested that fermentation-associated microbial metabolites exhibited higher antioxidant activity than original naringin. Obtained results contribute to a more comprehensive understanding of the microbial metabolism and antioxidant capacity of naringin.
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45

Kiyota, H., S. Otsuka, A. Yokoyama, S. Matsumoto, H. Wada, and S. Kanazawa. "Effects of highly volatile organochlorine solvents on nitrogen metabolism and microbial counts." Soil and Water Research 7, No. 3 (July 10, 2012): 109–16. http://dx.doi.org/10.17221/30/2011-swr.

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The effects of highly volatile organochlorine solvents (1,1,1-trichloroethane, TCET; trichloroethylene, TCE; and tetrachloroethylene, PCE) on soil nitrogen cycle and microbial counts were investigated using volcanic ash soil with different fertilizations. All the solvents significantly inhibited the activity of the cycle under the sealed conditions with 10 to 50 mg/g (dry soil) solvents added. No significant difference between the solvents, and between fertilization plots, was observed. Nitrate ion was not accumulated, and instead, ammonium ion was highly accumulated in the presence of the solvents. Nitrite ion was partially detected, while l-glutaminase activity was inhibited. The growths of ammonification, nitritation, nitratation and denitrification bacteria, and filamentous fungi were significantly inhibited in the presence of 10 mg/g (dry soil) of the solvents. 
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46

Dillard, Lillian R., Dawson D. Payne, and Jason A. Papin. "Mechanistic models of microbial community metabolism." Molecular Omics 17, no. 3 (2021): 365–75. http://dx.doi.org/10.1039/d0mo00154f.

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47

Gray, T. R. G., and G. A. Codd. "Aspects of Microbial Metabolism and Ecology." Journal of Applied Ecology 23, no. 1 (April 1986): 357. http://dx.doi.org/10.2307/2403111.

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48

Fitzpatrick, Paul F. "The enzymes of microbial nicotine metabolism." Beilstein Journal of Organic Chemistry 14 (August 31, 2018): 2295–307. http://dx.doi.org/10.3762/bjoc.14.204.

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Because of nicotine’s toxicity and the high levels found in tobacco and in the waste from tobacco processing, there is a great deal of interest in identifying bacteria capable of degrading it. A number of microbial pathways have been identified for nicotine degradation. The first and best-understood is the pyridine pathway, best characterized forArthrobacter nicotinovorans, in which the first reaction is hydroxylation of the pyridine ring. The pyrrolidine pathway, which begins with oxidation of a carbon–nitrogen bond in the pyrrolidine ring, was subsequently characterized in a number of pseudomonads. Most recently, a hybrid pathway has been described, which incorporates the early steps in the pyridine pathway and ends with steps in the pyrrolidine pathway. This review summarizes the present status of our understanding of these pathways, focusing on what is known about the individual enzymes involved.
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49

Wu, Bo, Feifei Liu, Wenwen Fang, Tony Yang, Guang-Hao Chen, Zhili He, and Shanquan Wang. "Microbial sulfur metabolism and environmental implications." Science of The Total Environment 778 (July 2021): 146085. http://dx.doi.org/10.1016/j.scitotenv.2021.146085.

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Amend, J. P., C. Saltikov, G. S. Lu, and J. Hernandez. "Microbial Arsenic Metabolism and Reaction Energetics." Reviews in Mineralogy and Geochemistry 79, no. 1 (January 1, 2014): 391–433. http://dx.doi.org/10.2138/rmg.2014.79.7.

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