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1

Jentzsch, Iris Miriam Vargas. "Comparative genomics of microsatellite abundance: a critical analysis of methods and definitions." Thesis, University of Canterbury. Biological Sciences, 2009. http://hdl.handle.net/10092/4282.

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This PhD dissertation is focused on short tandemly repeated nucleotide patterns which occur extremely often across DNA sequences, called microsatellites. The main characteristic of microsatellites, and probably the reason why they are so abundant across genomes, is the extremely high frequency of specific replication errors occurring within their sequences, which usually cause addition or deletion of one or more complete tandem repeat units. Due to these errors, frequent fluctuations in the number of repetitive units can be observed among cellular and organismal generations. The molecular mech
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Rose, Owen Charles. "The evolution of microsatellites." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286155.

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Khayms, Vadim. "Advanced propulsion for microsatellites." Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/8824.

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Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 2000.<br>Includes bibliographical references (leaves 162-166).<br>Microsatellites have become increasingly popular in recent years as they offer significant cost savings, higher reliability, and are generally more affordable for a large variety of commercial applications. Since many microsatellite missions require considerable propulsion capabilities, miniaturization of the propulsion subsystem is critical in the design of most miniature spacecraft. A broad range of existing propulsion technologies ha
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Chilakamarri, Sunita R. "Genetic differentiation in Alewife populations using microsatellite loci." Link to electronic thesis, 2005. http://www.wpi.edu/Pubs/ETD/Available/etd-053105-164623/.

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Bodnarik, Julia G., Dave Hamara, Michael Groza, et al. "Neutron detector development for microsatellites." SPIE-INT SOC OPTICAL ENGINEERING, 2017. http://hdl.handle.net/10150/627176.

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We present a preliminary design for a novel neutron detection system that is compact, lightweight, and low power consuming, utilizing the CubeSat platform making it suitable for space-based applications. This is made possible using the scintillating crystal lithium indium diselenide ((LiInSe2)-Li-6), the first crystal to include Li-6 in the crystalline structure, and a silicon avalanche photodiode (Si-APD). The schematics of this instrument are presented as well as the response of the instrument to initial testing under alpha, gamma and neutron radiation. A principal aim of this work is to dem
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Sheikh, Sanea. "Microsatellites in the Flycatcher Genome." Thesis, Uppsala universitet, Systematisk biologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-191385.

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Harr, Bettina. "Evolution of microsatellites in Drosophila." [S.l. : s.n.], 2000. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB8845129.

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Marouillat-Védrine, Sylviane. "Etudes des variations structurales chromosomiques dans l'autisme et la déficience mentale." Thesis, Tours, 2011. http://www.theses.fr/2011TOUR3133/document.

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L’autisme et la déficience mentale sont deux syndromes neuro-développementaux impliquant des facteurs génétiques. Notre travail a consisté à rechercher de nouveaux gènes candidats ou facteurs de susceptibilité chez 106 patients atteints d’autisme et 68 de déficience mentale non syndromique sporadique.Nous avons observé une association entre l’allèle 4 d’un marqueur microsatellite GXAlu localisé en 17q11.2 dans l’intron 27b du gène NF1 et des patients atteints de déficience mentale non-syndromique.Nous avons contribué à la mise en évidence d’une augmentation d’expression du transcrit NLGN4X, ch
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Karhu, A. (Auli). "Evolution and applications of pine microsatellites." Doctoral thesis, University of Oulu, 2001. http://urn.fi/urn:isbn:9514259246.

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Abstract The evolution of microsatellites was studied within and between the pine species. Sequences showed that microsatellites do not necessarily mutate in a stepwise fashion and that size homoplasy is common due to flanking sequence and repeat area changes within and between the species. Thus, some assumptions of statistical methods based on changes in repeat numbers may not hold. Sequences from cross-species amplifications revealed evidence of duplications of microsatellite loci in pines. On two independent occasions, the repeat area of the microsatellite had undergone a rapid expansi
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Taylor, Tiawanna. "The development of microsatellites for parrots (Psittaciformes)." Thesis, University of Nottingham, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288084.

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McLinko, Ryan (Ryan M. ). "Conceptual Phase Structural Design Tool for Microsatellites." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/67068.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 2011.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student submitted PDF version of thesis.<br>Includes bibliographical references (p. 122-124).<br>Gaining traction or momentum in the conceptual design phase for a complex system can be an arduous and daunting process, whether the complex system being designed is a satellite, airplane, car, or one of countless other systems. The des
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Csilléry, Katalin. "Statistical inference in population genetics using microsatellites." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/3865.

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Statistical inference from molecular population genetic data is currently a very active area of research for two main reasons. First, in the past two decades an enormous amount of molecular genetic data have been produced and the amount of data is expected to grow even more in the future. Second, drawing inferences about complex population genetics problems, for example understanding the demographic and genetic factors that shaped modern populations, poses a serious statistical challenge. Amongst the many different kinds of genetic data that have appeared in the past two decades, the highly po
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Loire, Etienne. "Evolution des microsatellites codants chez les primates." Paris 6, 2009. http://www.theses.fr/2009PA066495.

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Les microsatellites sont des séquences qui présentent des mécanismes mutationnels propres à leur nature répétée et qui aboutissent à de fréquents changements du nombre d’unité qui les composent. Cette nature hypermutable des microsatellites, extrêmement abondants dans les génomes eucaryotes, est responsable de leur polymorphisme élevé au sein des populations. Ces répétitions sont soumises à une force de sélection qui tend à les purger hors des gènes, en raison de l’instabilité qu’ils confèrent à ces derniers. Nous avons caractérisé les gènes humains qui contiennent un microsatellite codant ins
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Buschiazzo, Emmanuel. "Conservation and Evolution of Microsatellites in Vertebrate Genomes." Thesis, University of Canterbury. Biological Sciences, 2008. http://hdl.handle.net/10092/1595.

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Microsatellites are strings of short DNA motifs (≤6 bp) repeated in tandem across genomes of both prokaryotes and eukaryotes. In 20 years, they became popular genetic markers, successfully employed in the field of genetic mapping and gene hunting, as well as to address various biological questions at the individual, family, population and species level. However, evolutionary and demographic inferences from microsatellite polymorphism are hampered by controversy and ambiguity in the mutational processes of microsatellite sequences. Drawing on new data from genome projects, I review in Chapter 1
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Vowles, Edward Joseph. "The evolution of microsatellites and their flanking sequences." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439035.

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Khayms, Vadim. "Design of a miniaturized Hall thruster for microsatellites." Thesis, Massachusetts Institute of Technology, 1997. http://hdl.handle.net/1721.1/50313.

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Ross-Adams, Helen Esther. "The characterisation of selected grapevine cultivars using microsatellites." Thesis, Stellenbosch : Stellenbosch University, 2002. http://hdl.handle.net/10019.1/53092.

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Thesis (MScAgric)--Stellenbosch University, 2002.<br>ENGLISH ABSTRACT: Grapevine supports one of the oldest industries in South Africa today, and is also of significant international importance. With increasing international trade and the transport of fruit and other grapevine-derived products between borders, it has become increasingly important for South African farmers and viticulturalists to ensure their products conform to strict international market requirements if they are to remain competitive. Such requirements include the correct and accurate identification of berries and wine
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Leclercq, Sébastien. "Origines des séquences microsatellites dans les génomes eucaryotes." Phd thesis, Montpellier 2, 2007. http://www.theses.fr/2007MON20190.

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Les microsatellites sont des entités génomiques présentes dans tous les organismes vivants. Nous nous intéressons dans cette thèse à leur apparition, en se basant sur l'analyse de la séquence du génome humain. Il a tout d'abord fallu extraire les microsatellites, et il existe plusieurs algorithmes de fonctionnement différents pour cela. La première partie de cette thèse se concentre sur la comparaison de quelques-uns des algorithmes de recherche de répétitions en tandem, et dresse un portait de chacun des algorithmes. Deux possibilités majeures d'apparition des microsatellites sont détaillées.
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Leclercq, Sébastien. "Origines des séquences microsatellites dans les génomes eucaryotes." Phd thesis, Université Montpellier II - Sciences et Techniques du Languedoc, 2007. http://tel.archives-ouvertes.fr/tel-00261560.

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Les microsatellites, séquences répétées en tandem de période une à six paires de bases, sont des entités génomiques présentes dans tous les organismes qu'ils soient animaux, végétaux ou microbiens. Ils présentent un cycle de vie caractérisé par trois phases principales : une apparition et une maturation, une dynamique à l'état mature, puis une dégénérescence. Nous nous intéressons dans cette thèse à la première phase, l'apparition des microsatellites. <br />Pour traiter ces questions, nous nous sommes basés sur l'analyse de la séquence du génome humain. L'une des lacunes de ce type d'analyse e
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Bodur, Cagri. "Genetic Structure Analysis Of Honeybee Populations Based On Microsatellites." Phd thesis, METU, 2005. http://etd.lib.metu.edu.tr/upload/12606592/index.pdf.

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We analyzed the genetic structures of 11 honeybee (Apis mellifera) populations from T&uuml<br>rkiye and one population from Cyprus using 9 microsatellite loci. Average gene diversity levels were found to change between 0,542 and 0,681. Heterozygosity levels, mean number of alleles per population, presence of diagnostic alleles and pairwise FST values confirmed the mitochondrial DNA finding that Anatolian honeybees belong to north Mediterranean (C) lineage. We detected a very high level of genetic divergence among populations of T&uuml<br>rkiye and Cyprus based on pairwise FST levels (between 0
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Paetkau, David Henry. "Genetic studies of North American bear populations using microsatellites." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq23052.pdf.

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Duncan, Stuart. "Development and exploitation of GPS attitude determination for microsatellites." Thesis, University of Surrey, 2010. http://epubs.surrey.ac.uk/804951/.

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Fernandez-Salivar, Juan A. "Miniaturised UV imaging spectrometer for atmospheric monitoring from microsatellites." Thesis, University of Surrey, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502648.

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Bodo, Sahra. "Induction d'un processus d'instabilité des microsatellites du génome dans des modèles murin et cellulaire : intérêt physiopathologique et clinique." Thesis, Paris 6, 2014. http://www.theses.fr/2014PA066565/document.

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L'inactivation du système MMR (mismatch repair) favorise un processus oncogénique d'instabilité des microsatellites du génome (MSI). Au cours de ma thèse, j'ai étudié d'une part le rôle de l'azathioprine (Aza) dans l'induction de tumeurs MSI chez la souris. Des études épidémiologiques avaient rapporté une corrélation entre l'émergence de cancers MSI tardifs chez l'homme, et la prise au long cours de cet immunosuppresseur dont la cytotoxicité in vitro est médiée par l'activité MMR. Dans une étude dose-réponse, j'ai observé l'émergence de rares lymphomes MSI de survenue tardive chez la souris de
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Fouquet, Marc. "Earth imaging with microsatellites : an investigation, design, implementation and in-orbit demonstration of electronic imaging systems for Earth observation on-board low-cost microsatellites." Thesis, University of Surrey, 1995. http://epubs.surrey.ac.uk/844455/.

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This research programme has studied the possibilities and difficulties of using 50 kg microsatellites to perform remote imaging of the Earth. The design constraints of these missions are quite different to those encountered in larger, conventional spacecraft. While the main attractions of microsatellites are low cost and fast response times, they present the following key limitations: Payload mass under 5 kg, Continuous payload power under 5 Watts, peak power up to 15 Watts, Narrow communications bandwidths (9.6 / 38.4 kbps), Attitude control to within 5&deg;, No moving mechanics. The most sig
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Bond, Joanna Margaret. "Genetic analysis of the sperm whale (Physeter macrocephalus) using microsatellites." Thesis, University of Cambridge, 1999. https://www.repository.cam.ac.uk/handle/1810/265611.

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The sperm whale is the largest of the toothed whales (Odontoceti), and inhabits deep waters from equatorial to Polar Regions. Sperm whales are social and commonly l r . found in small groups. However, sociality varies according to sex and age. Immature males form bachelor groups that disperse as they mature, mature males are frequently encountered alone. Sperm whales are renowned for their diving capabilities. Therefore, surface observations are only possible for 10 to 15 minutes every hour. Consequently, the sperm whale is an ideal candidate for investigation using genetic markers. Genetic va
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Valsecchi, Elena. "Genetic analysis of the humpback whale (Megaptera novaeangliae) using microsatellites." Thesis, University of Cambridge, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242544.

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Fretwell, Neale. "A search for human Y-chromosome-specific minisatellites and microsatellites." Thesis, University of Leicester, 1996. http://hdl.handle.net/2381/34411.

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This thesis describes an attempt to isolate polymorphic minisatellite and microsatellite loci from the male-specific region of the human Y chromosome. Y chromosome polymorphisms are useful in the study of human evolution, since the majority of the chromosome is exempt from meiotic recombination and is passed down intact in paternal lineages. Y-specific polymorphisms can be used to identify males that are related by descent. Base substitutions and sequence insertions are ideal for such analysis, because they represent very rare events and are unlikely to recur. However, these mutations are ofte
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Delaugerre, Constance. "Diagnostic moléculaire de l'hémophilie A : évaluation de l'informativité des microsatellites." Paris 5, 1997. http://www.theses.fr/1997PA05P221.

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Wallace, Aaron L. "The taxonomic and systematic relationships of several salt marsh Fucus taxa (heterokontophyta, phaeophyceae) within the Gulf of Maine and Ireland examined using microsatellite markers." View this thesis online, 2005. http://libraries.maine.edu/gateway/oroauth.asp?file=orono/etheses/37803141.pdf.

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Thesis (Ph.D.)--University of New Hampshire (Dept. of Biochemistry and Molecular Biology), 2005.<br>Title from PDF title page. Available through UMI ProQuest Digital Dissertations. Includes bibliographical references. Also issued in print.
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Ramakrishna, W. "DNA fingerprinting and molecular characterization of microsatellites and minisatellites in rice." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1994. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2817.

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Prudhomme, Jorian. "Phlébotomes et écosystèmes : impact des facteurs biotiques et abiotiques sur la structure génétique et phénotypique des populations." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTS027/document.

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Les phlébotomes sont des insectes hématophages appartenant à la famille des Psychodidae et à la sous-famille des Phlebotominae. Cet insecte diptère, jaunâtre, relativement petit (2 à 3 mm) compte environ 800 espèces. 70 de ces espèces ont été identifiées comme vecteurs potentiels dont une quarantaine sont des vecteurs prouvés. Ils peuvent transmettre différents pathogènes dont les principaux sont les leishmanies et les phlébovirus. Ce travail de thèse est focalisé sur les phlébotomes vecteurs de la leishmaniose. Les leishmanioses sont des maladies parasitaires causées par un protozoaire du gen
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Santani, Avni Bhawan. "Genomic analysis of the horse Y chromosome." Texas A&M University, 2004. http://hdl.handle.net/1969.1/1494.

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Stallion fertility is of significant economic importance in the multibillion dollar equine industry. Presently, the underlying genetic causes of infertility in stallions are unknown. Analysis of the human genome has shown that in more than 25% of cases, male infertility is associated with deletions/rearrangements in the Y chromosome. Presently there is no gene map for the Y chromosome in the horse. Therefore, the primary aim of this study is to build a detailed physical map of the chromosome with a long-term aim to identify and analyze Y-specific factors affecting fertility in stallions. To m
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Gunn, Melissa Rose School of Biological Earth &amp Environmental Science UNSW. "The use of microsatellites as a surrogate for quantitative trait variation in conservation." Awarded by:University of New South Wales. School of Biological, Earth and Environmental Science, 2003. http://handle.unsw.edu.au/1959.4/22457.

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Conservation biologists are interested in maintaining genetic variation in small populations, with a view to maintaining fitness and the ability of the species to adapt to changing environmental conditions. The most important type of genetic variation is therefore that which affects fitness and reproduction, and is therefore subject to natural selection. Such fitness traits are often quantitative, i.e. are the result of a suite of loci, and are continuously variable. Microsatellite markers are a popular method of determining the level of variation present in a species??? genome. The assumption
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Lai, Yau-lin Caroline. "Genotyping of gestational trophoblastic disease." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B23427383.

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Duffy, Andrew J. "Genetic variability and population differentiation in Scandinavian wolverines." Connect to this title online, 1997. http://www.nlc-bnc.ca/obj/s4/f2/dsk2/ftp01/MQ36353.pdf.

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Long, Qiaoming. "Molecular cloning of chicken transforming growth factor β1 and isolation of microsatellites". Thesis, University of Edinburgh, 1995. http://hdl.handle.net/1842/29227.

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LORIDON, KARINE. "Analyse de la variabilite genetique de sequences microsatellites trinucleotidiques chez arabidopsis thaliana." Clermont-Ferrand 2, 1998. http://www.theses.fr/1998CLF22066.

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Les microsatellites sont de petites sequences repetees en tandem presentes en un grand nombre de loci dans les genomes eucaryotes. Ils se caracterisent par une hypervariabilite de taille due a des variations de leur nombre de repetitions. Notre analyse porte sur la variabilite genetique des microsatellites trinucleotidiques chez la plante modele arabidopsis thaliana. L'amplification pcr de 12 loci microsatellites a ete realisee pour 49 ecotypes d'arabidopsis thaliana. Ces microsatellites presentent un niveau de polymorphisme intraspecifique modere, avec un nombre moyen d'alleles par locus egal
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Pomares, Christelle. "Epidémiologie et formes cliniques atypiques de la leishmaniose à Leishmania infantum. : Apport du génotypage parasitaire." Thesis, Aix-Marseille, 2012. http://www.theses.fr/2012AIXM5055/document.

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La leishmaniose à Leishmania infantum est une zoonose transmise de mammifère à mammifère par la piqûre d'un insecte vecteur, le phlébotome femelle. S'il est classiquement décrit la leishmaniose viscérale avec la triade classique fièvre, pâleur et splénomégalie, de nombreuses formes cliniques peuvent être associées à ce parasite. Le portage asymptomatique est la forme la plus fréquente et la plus répandue dans l'Ancien Monde ou le Nouveau Monde. Entre la leishmaniose viscérale et le portage asymptomatique, plusieurs formes cliniques sont présentes. Ainsi certains sujets vont exprimer la leishma
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Beveridge, Maxine. "Molecular ecology of Dawson's burrowing bee Amegilla dawsoni (Hymenoptera: Anthophorini)." University of Western Australia. School of Animal Biology, 2006. http://theses.library.uwa.edu.au/adt-WU2006.0091.

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[Truncated abstract] In the last two decades, the use of microsatellites has revolutionized the study of ecology and evolution. Microsatellites, or short tandem repeats (STRs), are stretches of DNA repeats, 1 to 5 nucleotides long, where the number of repeats varies between individuals. They are co-dominant, highly variable, neutral markers, and are inherited in a Mendelian fashion. Microsatellite loci were isolated from Dawson’s burrowing bee, Amegilla dawsoni, a large, fast-flying solitary nesting bee endemic to the arid zone of Western Australia. Twelve polymorphic loci were found with an o
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Mallory, Melanie Ann. "Development and Characterization of Microsatellite Markers for the Grain Amaranths (Amaranthus spp. L.)." Diss., CLICK HERE for online access, 2007. http://contentdm.lib.byu.edu/ETD/image/etd1988.pdf.

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Choudhury, Arpita. "The use of microsatellite DNA fingerprinting for aquaculture and fisheries science /." View online ; access limited to URI, 2005. http://0-wwwlib.umi.com.helin.uri.edu/dissertations/dlnow/3186898.

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Chirhart, Scott Edward. "Evolutionary implications of microsatellite variation in the Peromyscus maniculatus species group." Texas A&M University, 2003. http://hdl.handle.net/1969.1/1279.

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Given the distribution and probable evolutionary history of the Peromyscus maniculatus species group, an interspecific comparison of microsatellite variation among these species would be logically based (at least initially) on primers isolated from the genome of a geographically central population of P. maniculatus. Additionally, as the species in the group are recently diverged, reasonably informative microsatellite data are likely to require analysis of a rapid evolving category of microsatellite loci. The initial phase of this research involved the isolation, characterization and assessme
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Martins, Aline Fernandes Angêlla [UNESP]. "Estrutura populacional de Anopheles darlingi em diferentes localidades de Rondônia ao longo do Rio Madeira através da genotipagem de microssatélites." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/102683.

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Made available in DSpace on 2014-06-11T19:32:13Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-01-28Bitstream added on 2014-06-13T20:23:14Z : No. of bitstreams: 1 martins_afa_dr_botib.pdf: 1302290 bytes, checksum: f4a20eda14cf780d998f0e02bf28f074 (MD5)<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)<br>A malária é uma das principais parasitoses humanas do mundo, causando mais de um milhão de mortes, e quase 500 milhões de casos agudos da doença por ano. No Brasil, esta doença continua sendo uma das mais importantes do país, tendo sido registrados no ano de 200
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Boley, Ryan Michael. "Relative species abundance and microhabitat preferences of larval Scaphirhynchus sturgeon in the middle Mississippi River." OpenSIUC, 2010. https://opensiuc.lib.siu.edu/theses/195.

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The pallid sturgeon (Scaphirhynchus albus) and shovelnose sturgeon (S. platorynchus) are benthic freshwater fishes that are sympatric throughout the range of the pallid sturgeon. Pallid sturgeon was listed as endangered under the Endangered Species Act in 1990, while shovelnose is common throughout the range. Previous abundance studies estimate the ratio of adult pallid to shovelnose sturgeon to be on the order of 1:82 in the middle Mississippi River, respectively. Despite adult abundances, reproduction and/or recruitment of pallid sturgeon larvae is undocumented in the middle Mississippi Rive
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Schwartz, Tonia S. "Population structure of the gopher tortise (sic) (Gopherus polyphemus) in Florida, using microsatellites." [Tampa, Fla.] : University of South Florida, 2003. http://purl.fcla.edu/fcla/etd/SFE0000607.

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Batley, Jacqueline. "A study of the population ecology of willow beetles (Phyllodecta spp.) using microsatellites." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343295.

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Johnson, Kirsten M. "Characterization of length-dependent GGAA-microsatellites in EWS/FLI mediated Ewing sarcoma oncogenesis." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1523384027382108.

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Croteau, Emily Katherine. "Population genetics and phylogeography of bobcats (Lynx rufus) using microsatellites and mitochondrial DNA." Available to subscribers only, 2009. http://proquest.umi.com/pqdweb?did=1791777601&sid=3&Fmt=2&clientId=1509&RQT=309&VName=PQD.

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Thesis (Ph. D.)--Southern Illinois University Carbondale, 2009.<br>"Department of Zoology." Keywords: Bobcats, Microsatellite, Mitochondrial DNA, Phylogeography, Population genetics, Lynx rufus. Includes bibliographical references (p. 98-111). Also available online.
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Brockhurst, Veronica. "Development of novel DNA-based methods for the measurement of length polymorphisms (microsatellites)." Thesis, Queensland University of Technology, 2001.

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