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Rozprawy doktorskie na temat „Multipore membranes”

Autor: Grafiati

Data publikacji: 2 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Freitas, Mariana Vaini de. "Influência do uso de estatinas sobre a estabilidade de membrana de eritrócitos em portadores de esclerose múltipla." Universidade Federal de Uberlândia, 2009. https://repositorio.ufu.br/handle/123456789/15814.

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Multiple sclerosis (MS), degenerative disease characterized by defects in the myelin membrane of neural cells, takes place probably by oxidative, inflammatory and autoimmune mechanisms in genetically vulnerable individuals, under the influence of environmental factors associated with feeding. [Hypothesis] As the structural composition of biological membranes is largely affected by diet, physical activity and use of medicines, the interference of environmental factors in the homeostasis of structural membranes of neural cells in carriers of MS must also be shared by other post-mitotic cells of

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Low, Andrew M. "Aspects of supersymmetry in multiple membrane theories." Thesis, Queen Mary, University of London, 2011. http://qmro.qmul.ac.uk/xmlui/handle/123456789/1328.

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This thesis consists of two parts. In the rst part we investigate the worldvolume supersymmetry algebra of multiple membrane theories. We begin with a description of M-theory branes and their intersections from the perspective of spacetime and worldvolume supersymmetry algebras. We then provide an overview of the recent work on multiple M2-branes focusing on the Bagger-Lambert theory and its relation to the Nambu-Poisson M5-brane and the ABJM theory. The worldvolume supersymmetry algebras of these theories are explicitly calculated and the charges interpreted in terms of spacetime intersection

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3

Ayoub, Fayad Mazen. "The interactions of paraproteins and albumin with artificial and biological membranes." Thesis, University of Essex, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295643.

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Yee, Kevin Wing Kan Chemical Sciences &amp Engineering Faculty of Engineering UNSW. "Operability analysis of a multiple-stage membrane process." Publisher:University of New South Wales. Chemical Sciences & Engineering, 2008. http://handle.unsw.edu.au/1959.4/41287.

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Membrane processes have found increasing industrial applications worldwide. For membrane processes to deliver their desired performances and mitigate the effect of disturbances, automatic controllers must be installed. Before the installation of controllers, operability analysis is a crucial step to evaluate how well the processes can be controlled, and to determine how process design can be improved for better control. However, existing applications of operability analysis in membrane processes are limited. This thesis extends the application of operability analysis to a multiple-stage mem

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5

Klunder, Lammert. "Sorting and trafficking of proteins in oligodendrocytes during myelin membrane biogenesis." [S.l. : Groningen : s.n. ; University Library of Groningen] [Host], 2007. http://irs.ub.rug.nl/ppn/.

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Hon, Gloudina Maria. "Membrane fluidity and fatty acids in multiple sclerosis patients." Thesis, Cape Peninsula University of Technology, 2009. http://hdl.handle.net/20.500.11838/1514.

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Thesis (DTech (Biomedical Technology))--Cape Peninsula University of Technology, 2009<br>Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS), which leads to neuronal demyelination, and eventually to oligodendrocyte and axon loss, with subsequent lesion formation. The wide distribution of lesions in the CNS results in a variety of clinical features, such as cognitive impairment, vertigo, spasticity, ataxia tremors, progressive quadriparesis, pain and depression. Currently no cure exists for CNS disorders, resulting in a decline in quality of life,

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7

Mirzabeygi, Marjan. "Les complications obstétricales et pédiatriques des grossesses triples : expérience de la Maternité de Bordeaux de 1989 à 1996." Bordeaux 2, 1997. http://www.theses.fr/1997BOR2M080.

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8

Shi, Xiafu. "Mechanisms of membrane fouling by macromolecules at multiple scales during ultrafiltration." Thesis, University of Oxford, 2014. https://ora.ox.ac.uk/objects/uuid:b9ffb933-fe45-4864-b20c-26f4714d3f02.

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The thesis aims to gain a better understanding on the mechanisms of the complicated macromolecular fouling in ultrafiltration (UF). The work is divided into three main parts. Firstly, comprehensive literature reviews on both membrane fouling and cleaning were carried out for a better overview on this problem. The findings such as the identification of the main foulants and the current knowledge on fundamental fouling mechanisms, directly contributed to further parts of the thesis. Secondly, a multiscale approach was developed to form generalised framework for modelling complex fouling scenario

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9

Hartmann, Anne Kathrin. "Multiple routes of phosphatidylethanolamine biogenesis ensure membrane integrity of Toxoplasma gondii." Doctoral thesis, Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2016. http://dx.doi.org/10.18452/17477.

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Toxoplasma gondii ist ein weit verbreiteter, obligat-intrazellulärer, einzelliger Parasit, der die lebensbedrohliche Krankheit Toxoplasmose in Menschen und Tieren hervorrufen kann. Der schnell replizierende Parasit benötigt erhebliche Mengen an Phospholipiden zur Biogenese intra- und extrazellulärer Membranen. Phosphatidylethanolamin (PtdEtn) ist ein wichtiges und ubiquitäres Phospholipid in Pro- und Eukaryoten und das zweithäufigste Lipid in T. gondii. Dieses kann de novo über den CDP-Ethanolamin Stoffwechselweg oder durch Decarboxylierung von Phosphatidylserin synthetisiert werden. Im Rahmen

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Hon, Gloudina Maria. "The role of N-6 and N-3 pufa ratios in the aetiology of multiple sclerosis." Thesis, Cape Peninsula University of Technology, 2009. http://hdl.handle.net/20.500.11838/1482.

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Thesis (MTech (BioMedical Technology))--Cape Peninsula University of Technology, 2006<br>In multiple sclerosis (MS) the myelin sheaths surrounding the axons in the brain are mainly affected by the disease process. Myelin consists for the most part of lipids and proteins. An abnormality in essential fatty acid metabolism is known to be present in patients with MS (Horrobin, 1979), reflected in a high ratio of n-6 to n-3 fatty acids in cell membranes. It has also been established previously that the pathogenesis of inflammatory disorders is aggravated by excessive consumption of n-6 fatty a

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11

Gantner, Benjamin N. "Dectin-1 and toll-like receptor 2 : recognition of pathogens through multiple receptors shapes the innate immune response /." Thesis, Connect to this title online; UW restricted, 2004. http://hdl.handle.net/1773/8346.

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12

Abbey, Sonja P. "Tolerance and Materials Design of Nanophotonic Amorphous Membranes for Broadband Chemical Sensing." Ohio University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1344311156.

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13

Potier, Lydie. "Etude par calorimétrie des changements d'état dans une émulsion multiple E/H/E : application aux.transferts de solvant entre les deux phases aqueuses." Compiègne, 1993. http://www.theses.fr/1993COMP664S.

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Dans le but de mettre en évidence des transferts de matière, nous avons étudié par analyse enthalpique différentielle les changements d'état d'émulsions multiples eau-dans-huile-dans-eau. Ces émulsions E/H/E sont composées de trois phases: une phase aqueuse interne dispersée dans une phase huileuse, elle même dispersée dans une phase aqueuse externe. En raison de cette structure vésiculaire, la phase huileuse joue le rôle d'une membrane liquide, membrane à travers laquelle il peut se produire des transferts de matière si il existe une différence de composition entre les deux milieux aqueux. Co

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14

Qu, Yan. "Regulation of Multiple Membrane Trafficking Pathways Stimulated by P2X7 Receptor Activation in Inflammatory Macrophages." Case Western Reserve University School of Graduate Studies / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=case1221066011.

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15

Petit, Jules. "Membrane Tethering in Plant Intercellular Communication : Structure-Function of Multiple C2 domains and Transmembrane Region Proteins (MCTP) at Plasmodesmata ER-PM Membrane Contact Site." Thesis, Bordeaux, 2022. https://tel.archives-ouvertes.fr/tel-03789611.

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La multicellularité chez les plantes repose sur une communication intercellulaire qui permette le transfert d'informations à travers l'entièreté de l'organisme. Chez les plantes terrestres, la route principale de ces “conversations cellulaires” est assurée par les plasmodesmes (PD), des canaux nanoscopiques qui traversent la paroi pecto-cellulosique. En effet, ces pores sont impliqués dans la circulation d'une très grande variété de molécules, comme des facteurs de transcription, de l'ARN, des hormones et des métabolites et ceci à tous les stades de la vie végétale, permettant réponses et adap

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16

Avendano, Gomez Juan Ramon. "Etude par calorimétrie du mûrissement de composition dans une émulsion multiple H1/eau/H2." Compiègne, 2002. http://www.theses.fr/2002COMP1397.

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Ce travail concerne l'étude du mûrissement de composition dans une émulsion mixte Hl-H2 / Eau et une émulsion multiple Hl/ Eau 1H2. L'analyse calorimétrique différentielle (D. S. C. ) a permis d'étudier l'influence des paramètres de la formulation sur la structure et l'évolution de la composition des émulsions. La D. S. C. A permis également de quantifier le transfert de matière se produisant au sein de ces émulsions. D'abord le tetradécane et l'hexadécane ont été caractérisés en volume macroscopique, en émulsion simple ainsi que leurs mélanges. La D. S. C a permis de déterminer la température

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17

Zhang, Dacheng. "Contribution to prognostics of proton exchange membrane fuel cells : approaches based on degradation information at multiple levels." Thesis, Université Grenoble Alpes (ComUE), 2018. http://www.theses.fr/2018GREAT003/document.

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Dans le contexte de la transition énergétique, la pile à combustible devient l'une des sources d'énergie alternatives les plus prometteuses. Récemment, la recherche a mis l’accent sur les piles à combustible, et plus particulièrement sur celles à membrane échange de protons (Proton Exchange Membrane Fuel Cell ou Polymer Electrolyte Membrane Fuel Cell ou PEMFC) qui est l'une des meilleures candidates pour les applications stationnaires et transport. Même si cette technologie évolue constamment, elle n'est pas encore prête pour un déploiement industriel à grande échelle en raison de sa durabilit

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18

Potier, Lydie. "Etude par calorimétrie des changements d'état dans une émulsion multiple E/H/E : application aux transferts de solvant entre les deux phases aqueuses." Compiègne, 1993. http://www.theses.fr/1993COMPD664.

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Dans le but de mettre en évidence des transferts de matière, nous avons étudié par analyse enthalpique différentielle les changements d'état d'émulsions multiples eau-dans-huile-dans-eau. Ces émulsions E/H/E sont composées de trois phases: une phase aqueuse interne dispersée dans une phase huileuse, elle même dispersée dans une phase aqueuse externe. En raison de cette structure vésiculaire, la phase huileuse joue le rôle d'une membrane liquide, membrane à travers laquelle il peut se produire des transferts de matière si il existe une différence de composition entre les deux milieux aqueux. Co

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19

Fallarino, Lorena. "Anti HIV-1 gene therapy approach combining multiple siRNAs with the membrane-anchored fusion inhibitor C-peptide maC46." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3426674.

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The development of highly active anti-retroviral therapy (HAART) has considerably improved life expectancy of HIV-1 positive patients by transforming this infection, which once was lethal, into a manageable chronic illness. Although a significant suppression of viral replication under undetectable level is guaranteed following a constant therapeutic adherence, this therapy fails to completely eliminate the infection due to the persistence of HIV-1 into reservoirs, which represent therefore the main obstacle to a definite cure. Furthermore, a lifelong adherence to treatment is associated with d

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20

Riou, Mickaël. "Rôles et régulation des P-glycoprotéines de membrane impliquées dans les mécanismes de résistance multiple des nématodes parasites des petits ruminants aux anthelminthiques." Tours, 2005. http://www.theses.fr/2005TOUR4001.

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Les P-glycoprotéines (P-gp) jouent un rôle primordial dans la résistance multiple aux anthelminthiques des nématodes parasites des petits ruminants. Ce travail de thèse a permis de décrire le premier schéma du transport des anthelminthiques pour un modèle œuf de nématode impliquant les P-gp et de montrer le rôle de l’environnement membranaire dans leur activité. Les anthelminthiques pénétreraient dans les œufs soit par diffusion passive soit par capture directe par les P-gp (influx). Les anthelminthiques activeraient les P-gp et changeraient leur conformation. Les P-gp activées éliminent les a

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21

Hoffman, Mary M. "Mechanism of MDR protein mediated multidrug resistance /." Access full-text from WCMC, 1997. http://proquest.umi.com/pqdweb?did=733008491&sid=6&Fmt=2&clientId=8424&RQT=309&VName=PQD.

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Chang, Chien-Ti. "Effects of Homogenization and Ultra-high Temperature Processing on the Properties of Whole Milk Concentrated by a Multiple-Membrane Separation System." DigitalCommons@USU, 1995. https://digitalcommons.usu.edu/etd/5414.

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Three different concentrated whole milks (2.5x, 2.75x, and 3.0x) were produced by mixing equal parts of ultrafiltration retentate of whole milk and reverse osmosis retentate of the UF milk permeate. The concentrated whole milks were ultra-high temperature processed by direct steam injection (140.6°C) followed by flash cooling and two-stage homogenization pressures (2500/500 psi, 3500/700 psi, or 4500/900 psi). The milk concentrates were packaged aseptically and stored at room temperature. On the other hand, the milk concentrates produced by the RO single membrane system with the same concentra

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Hartmann, Anne Kathrin [Verfasser], Richard [Akademischer Betreuer] Lucius, Kai [Akademischer Betreuer] Matuschewski, and Thomas [Akademischer Betreuer] Günther-Pomorski. "Multiple routes of phosphatidylethanolamine biogenesis ensure membrane integrity of Toxoplasma gondii / Anne Kathrin Hartmann. Gutachter: Richard Lucius ; Kai Matuschewski ; Thomas Günther-Pomorski." Berlin : Lebenswissenschaftliche Fakultät, 2016. http://d-nb.info/1098257731/34.

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Guo, Xiaofeng 1976. "Understanding the multiple roles of the CA-SP1 boundary region in HIV-1 Gag multimerization, gag-membrane binding and viral RNA packaging." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111821.

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The Gag protein of human immunodeficiency virus type 1 (HIV-1) contains a 14 amino acid region termed SP1 that is located between the capsid (CA) and downstream nucleocapsid (NC) sequences, and plays an active role in Gag assembly. This activity of SP1 involves its amino-terminal residues that, together with adjacent CA residues, constitute a putative (x-helical structure spanning Gag residues from positions 359 to 371. However, the underlying mechanisms are mostly unclear. The major goal of this PhD study was to understand the role of SP1 in HIV-1 Gag multimerization, membrane binding and vir

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25

Li, Jinan. "Multifunctional roles of plasmin in inflammation : Studies of animal models on rheumatoid arthritis, multiple sclerosis, wound healing and infection." Doctoral thesis, Umeå : Dept. of medical biochemistry and biophysics, Univ, 2005. http://www.diva-portal.org/umu/theses/abstract.xsql?dbid=422.

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Hakizimana, Pierre. "Phosphatidylethanolamine regulates the function and the structure of LmrP, a bacterial multidrug transporter protein associated to antibiotic resistance." Doctoral thesis, Universite Libre de Bruxelles, 2008. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210486.

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The multidrug transporter LmrP, member of the major facilitator superfamily (MFS), confers L. lactis and recombinant E. coli cells resistance to an array of cytotoxic compounds including antibiotics. LmrP mediates drug extrusion from the plasma membrane by an electrogenic proton/drug exchange reaction, whereby a positively charged substrate may move towards the external medium in exchange for two or more protons moving towards the cytoplasm. Recent studies have suggested that MFS transporters require phosphatidylethanolamine (PE) for function and proper topology. However, the specificity of th

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Edqvist, Petra J. "Multiple twists in the molecular tales of YopD and LcrH in type III secretion by Yersinia pseudotuberculosis." Doctoral thesis, Umeå : Umeå University, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-985.

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Moissonnier, Loïck. "Etude fonctionnelle et structurale du transporteur de multiple drogues, BmrA, en condition d’équilibre et en temps résolu. Caractérisation structurale de BmrA en liposome par cryoEM." Electronic Thesis or Diss., Lyon 1, 2024. http://www.theses.fr/2024LYO10213.

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Selon l’organisation mondiale de la santé, la résistance aux antibiotiques est un problème majeur pour l’humanité en raison de l’émergence de bactérie multi-résistantes. L’émergence de ces résistances chez les bactéries provient du fait qu’elles sont capables de mettre en place de nombreuses stratégies pour empêcher les antibiotiques de fonctionner. En particulier, la première ligne de défense de ces bactéries est la surexpression de transporteurs ABC (ATP-Binding Cassette) qui expulsent les antibiotiques en dehors de la cellule bactérienne, diminuant leurs concentrations sous leurs seuils de

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Lacey, Erica. "The role of CD5 in T lymphocyte activation." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:c88d2845-4454-4b98-9814-64b9bbf22e04.

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Barets, Frédéric. "Œdèmes aigus du poumon et grossesse gémellaire : à propos de 4 cas observés à la Réunion aux décours de traitements tocolytiques par bêtamimétiques." Bordeaux 2, 1998. http://www.theses.fr/1998BOR2M041.

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Jelena, Bajac. "Dobijanje emulzionih nosača aktivnih materija primenom homogenizera i membranskim emulgovanjem u ćeliji sa mešanjem." Phd thesis, Univerzitet u Novom Sadu, Tehnološki fakultet Novi Sad, 2018. https://www.cris.uns.ac.rs/record.jsf?recordId=107583&source=NDLTD&language=en.

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Cilj ove doktorske disertacije je dobijanje vi&scaron;estrukih V<sub>1</sub>/U/V<sub>2</sub> emulzija kao nosača aktivnih materija u dvostepenom postupku, pri čemu se za drugi korak pripreme koristi tehnika membranskog emulgovanja (ME), na membrani od sinterovanog stakla implementiranoj u ćeliju sa me&scaron;anjem. Proces ME koristi se u svrhu unapređenja karakteristika formiranih emulzija, u smislu bolje kontrole veličine i raspodele veličina formiranih kapi, koje mogu da dovedu do razlika u stepenu inkapsulacije aktivnih materija u unutra&scaron;njoj vodenoj fazi, u odnosu na proces u kome s

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Fu, Josephine K. Y. "Functional characterization of the teleost multiple tissue (tmt) opsin family and their role in light detection." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:39bc18bb-16cb-4549-94cd-5f872daafe7e.

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In addition to a central circadian clock in the suprachiasmatic nucleus (SCN), zebrafish (Danio rerio) have local clock systems in their peripheral tissues. These peripheral tissues express a complement of clock genes that can be synchronized with the 24 h light/dark cycle and thus may be entrained by light. To date, teleost multiple tissue (tmt) opsin identified from Fugu rubripes and Danio rerio is the only opsin that has been proposed as a candidate to mediate this cellular photoentrainment (Moutsaki et al., 2003). Here we report the discovery of a multigene family of tmt opsins found not o

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Mannechez, Aurélie. "Le signal des lipides mobiles en résonance magnétique nucléaire du proton dans les cellules cancéreuses, l'acquisition de la multi-résistance aux drogues et l'apoptose." Rennes 1, 2003. http://www.theses.fr/2003REN1B070.

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Le signal lipides mobiles (lm) correspond en résonance magnétique nucléaire du proton à la résonance des protons des groupements méthyl et méthylène de chaînes d'acides gras. La localisation intracellulaire exacte de ces molécules en diffusion isotrope n'a pas encore été clairement démontrée mais deux hypothèses existent : ces lipides seraient organisés soit en microdomaines intercalés dans la membrane plasmique, soit dans les goutttelettes cytosoliques. Ce signal est une caractéristique des cellules cancéreuses et il varie avec l'acquisition de la multirésistance aux drogues (MDR) et l'entrée

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Kilburg, Arnaud. "Cristallisation du transporteur ABC BmrA de Bacillus subtilis : développement d’une nouvelle méthode de dosage des détergents par Matrix-Assisted Laser Desorption Ionization (MALDI)." Thesis, Lyon 1, 2015. http://www.theses.fr/2015LYO10116/document.

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Notre projet vise à déterminer la structure 3D du transporteur BmrA de Bacillus subtilis. La protéine a été purifiée dans six détergents différents. L'utilisation de foscholine 12, a conduit à cristalliser OmpF, une porine de la membrane externe d'E. coli. Nous montrons que les conditions de cristallisation influencent directement l'empilement cristallin d'OmpF. Le protocole de purification de BmrA, optimisé en utilisant du triton X100 à l'extraction puis un mélange β-D-dodecyl maltoside-cholate pour les étapes chromatographiques nous a permis d'obtenir à 4°C des cristaux, pour lesquels nous a

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Matar, Merheb Rachel Rima. "Caractérisation d’une nouvelle génération de détergents stabilisateurs des transporteurs abc en solution : cristallisation de BmrA, transporteur ABC bactérien." Thesis, Lyon 1, 2010. http://www.theses.fr/2010LYO10303.

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En raison de leur résistance aux agents chimiothérapeutiques, les transporteurs ABC de phénotype MDR ont attiré l'attention de la communauté scientifique. Notre projet vise à trouver des conditions dans lesquelles les transporteurs ABC restent fonctionnels en solution pour aboutir à la cristallisation de ces protéines dans une conformation active. Dans ce but, nous avons conçu et développé une nouvelle classe de détergents, à base de calix[4]arène, qui stabilisent ces protéines. Afin de résoudre la structure 3D à résolution atomique du transporteur ABC bactérien "BmrA", responsable de la résis

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Hsu, Lin-Fang, and 徐琳芳. "Multiple Phase Flow Simulation of a Tubular-Membrane Hydrocyclone." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/62261284230141484025.

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碩士<br>淡江大學<br>化學工程與材料工程學系碩士班<br>102<br>This study uses black silicon carbide powder as experimental particles to realize its classification in a 2.5 cm diameter hydrocyclone that equips membrane tube in center position. In the experiment, the effects of variations in inlet pressure on particle size distribution efficiency were analyzed. In the simulation of the change the size of the membrane tube, the air core and the flow pattern in hydrocyclone was simulated by VOF model and LES model, and using the discrete phase model to track and predict the particle motion. The simulation and experiment

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Hung, Fu-Hsin, and 洪福信. "Multiple allotypic forms of human membrane-bound Ig��1." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/65860024007623153024.

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碩士<br>國立清華大學<br>生物科技研究所<br>93<br>In humans, IgA has two subclasses, IgA1 and IgA2, which contain, respectively, a1 and a2 heavy chains, respectively. For both subclasses, there are also membrane-bound forms, mIgA1, and mIgA2, containing ma1 and ma2 heavy chains. Ma1 and ma2 differ from a1 and a2 by having a “membrane-anchor” peptide segment extending from the C-termini of a1 and a2. The membrane-anchor segment has three parts: an extracellular, a trans-membrane, and an intracellular segments. It was found previously that ma1 exists in a short and a long isoforms, referred to as ma1(S) and ma

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WU, YUNG-CHUN, and 吳詠群. "Multiple membrane blood feeding system for mosquito repellent bioassay." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/h6wfag.

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碩士<br>嘉南藥理大學<br>生物科技系<br>107<br>An efficient and safe in vitro bioassay system using a multiple-membrane blood-feeding device and a cocktail meal was used to identify the new insect repellents by the high-throughput screening of candidate chemicals. The method for standardizing the efficacy of repellents against Aedes aegypti should confirm the dose of repellent treatment on the skin surface, the repellent protection time, the type and physiological condition of the test mosquito, and the reproducibility of test results. The in vitro test were conducted in the airflow treatment through 1, 2, 3

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Yi-HongChen and 陳羿宏. "Sound Transmission of Membrane-type Acoustic Metamaterials with Multiple Frame Masses." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/52897781660719393873.

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碩士<br>國立成功大學<br>工程科學系<br>102<br>In recent years, acoustic metamaterials have displayed superior sound insulation quality at low frequencies. Low frequency noise is often associated with machines when they are being operated. It is hard to prevent this type of disturbance with a traditional heavy concrete wall. It is much easier to achieve this using acoustic metamaterials. Although the structure of these metamaterials is light and thin, they still work well for insulating noise. In this thesis, we use finite element analysis to simulate membrane-type acoustic metamaterials in order to explore

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Liu, Chieh Yuan, and 劉介元. "Hydrogen Ion Sensing Characteristics of Multiple Sensing Membranes Structure with Embedded Si3N4 Trapping Layer." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/37229523334044963705.

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碩士<br>長庚大學<br>電子工程學系<br>98<br>In this study, a novel multiple sensing membranes structure embedded with Si3N4 trapping layer was fabricated to investigate the sensing properties of hydrogen ions, it combine the conventional EIS structure and the charge trapping layer structure of the nonvolatile memory. According to the whole device structure, we call it as Reference Electrode Insulator Nitride Oxide Semiconductor (RINOS). We proposed a new device structure which has Silicon Nitride (Si3N4) as the charge-trapping layer, hafnium oxide (HfO2) as the sensing membrane. During the various voltage s

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Mafukidze, Nielsen Yamurai. "Synthesis of an integrated water and membrane network with multiple electrodialysis regenerators." Thesis, 2016. http://hdl.handle.net/10539/21102.

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The increasing cost of freshwater and wastewater treatment coupled with stringent environmental regulations has pushed process industries towards sustainable engineering, emphasising the need for water minimisation. This can be achieved through the implementation of process integration strategies such as water recycle, reuse, regeneration-recycle and regeneration-reuse between water sources, water sinks and regenerators. This concept is referred to as water allocation planning (WAP). This work addresses the WAP problem through the application of process integration and its enabling tools. A co

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Pei-ChiKuo and 郭佩棋. "Hydrogen and carbon dioxide separation in single and multiple palladium membrane tube systems." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/hbyqza.

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Yang, Shu-Chiao, and 楊樹橋. "Numerical simulation of Organic Solvent Nanofiltration (OSN) membrane separation performance in multiple stage cascades." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/36792111214868467494.

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碩士<br>中原大學<br>生物環境工程研究所<br>101<br>This research studied the numerical simulation of membrane separation performance in multiple stage cascades. A whole module was based on mass balance and simulated with software MATLAB for first-order differential equations. The concentration, purity and yield in each stage by using the rejection of solute for organic solvent nanofiltration membrane were studied. 　　In this research a complete model according to the set up conditions was verified by previous experimental data and shown in good agreement. For various operating conditions such as average permeat

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Chang, Chia-Yin, and 張家寅. "Simultaneous Detection of Multiple Proteins Using Functionalized Metal Nanoparticles Coupled with Microporous Membrane Substrate and Laser Desorption/ionization Mass Spectrometry." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/nxubnh.

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碩士<br>國立臺灣海洋大學<br>生命科學暨生物科技學系<br>104<br>In this work we demonstrate a simple assay for the simultaneous detection of multiple proteins by functionalized nanomaterials assisted laser-induced desorption/ionization mass spectrometry (LDI-MS). We chose thrombin, vascular endothelial growth factor-A165 (VEGF-A165) and platelet-derived growth factor-BB (PDGF-BB) as model proteins to demonstrate our sensing method. Selective detection of these analytes was achieved by modifying nanoparticles of three different metals (Au, Ag and Pt) with their corresponding aptamer or antibody. Functionalized metal n

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Crank, Michelle C. "Understand the mechanism of action of Rutuximab® in the reversal of multidrug resistance in a Non-Hodgkins Lymphoma cell line." 2006. http://edissertations.library.swmed.edu/pdf/CrankM030206/CrankMichelle.pdf.

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Diogo, Joana Margarida Santos. "Assess of catechol-O-methyltransferase soluble isoform by multiple reaction monitoring mass spectrometry." Master's thesis, 2016. http://hdl.handle.net/10400.6/6788.

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COMT is an enzyme that catalyses the transfer of the methyl group from S-adenosyl-L-methionine to the hydroxyl group of a large variety of catechols, including catechol-estrogens and the neurotransmitters dopamine and norepinephrine. The protein is expressed in both a soluble form (SCOMT) and a membrane-bound form with additional 50 residues at the N-terminal (MBCOMT). In most human tissues, the majority of COMT is present in soluble form and only a small fraction as MBCOMT. The human COMT gene has a common single-nucleotide polymorphism that results in substitution of methionine for valine at

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Durandt, Chrisna. "P-glikoproteien neutraliseringspotensiaal en weefsel verspreiding van tetrametiel-piperidien derivate van klofasimien (Afrikaans)." Thesis, 2000. http://hdl.handle.net/2263/27640.

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Dodelet-Devillers, Aurore. "The importance of the Hedgehog signaling pathway at the level of the blood-brain barrier." Thèse, 2009. http://hdl.handle.net/1866/3631.

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La barrière hémato-encéphalique (BHE) protège le système nerveux central (SNC) en contrôlant le passage des substances sanguines et des cellules immunitaires. La BHE est formée de cellules endothéliales liées ensemble par des jonctions serrées et ses fonctions sont maintenues par des astrocytes, celles ci sécrétant un nombre de facteurs essentiels. Une analyse protéomique de radeaux lipidiques de cellules endothéliales de la BHE humaine a identifié la présence de la voie de signalisation Hedgehog (Hh), une voie souvent liées à des processus de développement embryologique ainsi qu’au niveau des

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Koucký, Václav. "Detekce časných patofyziologických změn dýchání u dětí s chronickým plicním onemocněním." Doctoral thesis, 2020. http://www.nusl.cz/ntk/nusl-412517.

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Detection of early pathophysiological changes of breathing in children with chronic respiratory disease MD. Vaclav Koucky - Ph.D. thesis Abstract Introduction: Currently, there are different methods for infant pulmonary function testing (iPFT) and morphological assessment of microscopic changes in endobronchial biopsy samples (EBB). In research setting, they allow detection of early pathophysiological changes of breathing in small children with chronic respiratory disease, respectively in risk of its development. Their clinical significance, however, is not fully acknowledged. The aim of this

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McCanna, David. "Development of Sensitive In Vitro Assays to Assess the Ocular Toxicity Potential of Chemicals and Ophthalmic Products." Thesis, 2009. http://hdl.handle.net/10012/4338.

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The utilization of in vitro tests with a tiered testing strategy for detection of mild ocular irritants can reduce the use of animals for testing, provide mechanistic data on toxic effects, and reduce the uncertainty associated with dose selection for clinical trials. The first section of this thesis describes how in vitro methods can be used to improve the prediction of the toxicity of chemicals and ophthalmic products. The proper utilization of in vitro methods can accurately predict toxic threshold levels and reduce animal use in product development. Sections two, three and four describe t

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