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1

Lalanne, Jean-Benoît. "Multiscale dissection of bacterial proteome optimization." Thesis, Massachusetts Institute of Technology, 2020. https://hdl.handle.net/1721.1/130217.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Physics, May, 2020<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references (pages 315-348).<br>The quantitative composition of proteomes results from biophysical and biochemical selective pressures acting under system-level resource allocation constraints. The nature and strength of these evolutionary driving forces remain obscure. Through the development of analytical tools and precision measurement platforms spanning biological scales, we found evidence of optimization in bacterial
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Fitriani. "Multiscale Dynamic Time and Space Warping." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/45279.

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Thesis (S.M.)--Massachusetts Institute of Technology, Computation for Design and Optimization Program, 2008.<br>Includes bibliographical references (p. 149-151).<br>Dynamic Time and Space Warping (DTSW) is a technique used in video matching applications to find the optimal alignment between two videos. Because DTSW requires O(N4) time and space complexity, it is only suitable for short and coarse resolution videos. In this thesis, we introduce Multiscale DTSW: a modification of DTSW that has linear time and space complexity (O(N)) with good accuracy. The first step in Multiscale DTSW is to app
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Yourdkhani, Mostafa. "Multiscale modeling and optimization of seashell structure and material." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=66991.

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The vast majority of mollusks grow a hard shell for protection. Typical seashells are composed of two distinct layers, with an outer layer made of calcite (a hard but brittle material) and an inner layer made of a tough and ductile material called nacre. Nacre is a biocomposite material that consists of more than 95% of tablet-shape aragonite, CaCO3, and a soft organic material as matrix. Although the brittle ceramic aragonite composes a high volume fraction of nacre, its mechanical prop-erties are found to be surprisingly higher than those of its constituents. It has been su
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Umoh, Utibe Godwin. "Multiscale analysis of cohesive fluidization." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/28988.

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Fluidization of a granular assembly of solid particles is a process where particles are suspended in a fluid by the upward flow of fluid through the bed. This process is important in industry as it has a wide range of applications due to the high mixing and mass transfer rates present as a result of the rapid movement of particles which occurs in the bed. The dynamics of fluidization is heavily dependent on the particle scale physics and the forces acting at a particle level. For particles with sizes and densities less than 100μm and 103 kg/m3, the importance of interparticle forces such as co
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Sorrentino, Luigi. "Simulation and optimization of crowd dynamics using a multiscale model." Doctoral thesis, Universita degli studi di Salerno, 2012. http://hdl.handle.net/10556/318.

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2010 - 2011<br>In the last decades, the modeling of crowd motion and pedestrian .ow has attracted the attention of applied mathematicians, because of an increasing num- ber of applications, in engineering and social sciences, dealing with this or similar complex systems, for design and optimization purposes. The crowd has caused many disasters, in the stadiums during some major sporting events as the "Hillsborough disaster" occurred on 15 April 1989 at Hills- borough, a football stadium, in She¢ eld, England, resulting in the deaths of 96 people, and 766 being injured that remains the d
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Chen, Xing. "Flexoelectric Effect of Heterogeneous Structure and Its Multiscale Topology Optimization." Electronic Thesis or Diss., Université Gustave Eiffel, 2024. http://www.theses.fr/2024UEFL2023.

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Au cours des dernières décennies, la flexoélectricité a suscité un intérêt croissant pour convertir l'énergie vibratoire ambiante en énergie électrique. La flexoélectricité est un phénomène électromécanique qui associe des champs électriques à des gradients de déformation et induit inversement une déformation mécanique pour un gradient de champ électrique. Ce phénomène est inhérent à tous les matériaux diélectriques, et peut être significatif aux très petites échelles. L'universalité et le remarquable effet d'échelle de l'effet flexoélectrique sont prometteurs pour la conception de systèmes él
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Parno, Matthew David. "A multiscale framework for Bayesian inference in elliptic problems." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/65322.

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Thesis (S.M.)--Massachusetts Institute of Technology, Computation for Design and Optimization Program, 2011.<br>Page 118 blank. Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 112-117).<br>The Bayesian approach to inference problems provides a systematic way of updating prior knowledge with data. A likelihood function involving a forward model of the problem is used to incorporate data into a posterior distribution. The standard method of sampling this distribution is Markov chain Monte Carlo which can become inefficient in high dimensions, wasting many evaluat
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MEJIAS, TUNI JESUS ALBERTO. "Multiscale approach applied to fires in tunnels, Model optimization and development." Doctoral thesis, Politecnico di Torino, 2022. http://hdl.handle.net/11583/2960751.

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Chen, Minghan. "Stochastic Modeling and Simulation of Multiscale Biochemical Systems." Diss., Virginia Tech, 2019. http://hdl.handle.net/10919/90898.

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Numerous challenges arise in modeling and simulation as biochemical networks are discovered with increasing complexities and unknown mechanisms. With the improvement in experimental techniques, biologists are able to quantify genes and proteins and their dynamics in a single cell, which calls for quantitative stochastic models for gene and protein networks at cellular levels that match well with the data and account for cellular noise. This dissertation studies a stochastic spatiotemporal model of the Caulobacter crescentus cell cycle. A two-dimensional model based on a Turing mechanism is in
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Ahamad, Intan Salwani. "Multiscale line search in interior point methods for nonlinear optimization and applications." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612762.

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Arabnejad, Sajad. "Multiscale mechanics and multiobjective optimization of cellular hip implants with variable stiffness." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119630.

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Bone resorption and bone-implant interface instability are two bottlenecks of current orthopaedic hip implant designs. Bone resorption is often triggered by mechanical bio-incompatibility of the implant with the surrounding bone. It has serious clinical consequences in both primary and revision surgery of hip replacements. After primary surgery, bone resorption can cause periprosthetic fractures, leading to implant loosening. For the revision surgery, the loss of bone stock compromises the ability of bone to adequately fix the implant. Interface instability, on the other hand, occurs as a resu
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Petay, Margaux. "Multimodal and multiscale analysis of complex biomaterials : optimization and constraints of infrared nanospectroscopy measurements." Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPASF092.

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Dans le domaine du biomédical, l'étude des changements physico-chimiques induits par une pathologie au sein des tissus, à l'échelle cellulaire, peut être cruciale pour élucider les mécanismes à l'origine de ce phénomène. Toutefois, seules quelques techniques d'analyse permettent une description chimique à cette échelle. La nanospectroscopie infrarouge, en particulier l'AFM-IR (Microscopie à Force Atomique-Infrarouge) est prometteuse en permettant une description chimique des matériaux à l'échelle nanométrique. Actuellement, l'AFM-IR est souvent utilisée pour l'étude des cellules et micro-organ
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Sato, Ayami. "A structural optimization methodology for multiscale designs considering local deformation in microstructures and rarefied gas flows in microchannels." Kyoto University, 2019. http://hdl.handle.net/2433/242495.

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Xia, Liang. "Towards optimal design of multiscale nonlinear structures : reduced-order modeling approaches." Thesis, Compiègne, 2015. http://www.theses.fr/2015COMP2230/document.

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L'objectif principal est de faire premiers pas vers la conception topologique de structures hétérogènes à comportement non-linéaires. Le deuxième objectif est d’optimiser simultanément la topologie de la structure et du matériau. Il requiert la combinaison des méthodes de conception optimale et des approches de modélisation multi-échelle. En raison des lourdes exigences de calcul, nous avons introduit des techniques de réduction de modèle et de calcul parallèle. Nous avons développé tout d’abord un cadre de conception multi-échelle constitué de l’optimisation topologique et la modélisation mul
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Dang, Hieu. "Adaptive multiobjective memetic optimization: algorithms and applications." Journal of Cognitive Informatics and Natural Intelligence, 2012. http://hdl.handle.net/1993/30856.

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The thesis presents research on multiobjective optimization based on memetic computing and its applications in engineering. We have introduced a framework for adaptive multiobjective memetic optimization algorithms (AMMOA) with an information theoretic criterion for guiding the selection, clustering, and local refinements. A robust stopping criterion for AMMOA has also been introduced to solve non-linear and large-scale optimization problems. The framework has been implemented for different benchmark test problems with remarkable results. This thesis also presents two applications of these
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Carriou, Vincent. "Multiscale, multiphysic modeling of the skeletal muscle during isometric contraction." Thesis, Compiègne, 2017. http://www.theses.fr/2017COMP2376/document.

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Les systèmes neuromusculaire et musculosquelettique sont des systèmes de systèmes complexes qui interagissent parfaitement entre eux afin de produire le mouvement. En y regardant de plus près, ce mouvement est la résultante d'une force musculaire créée à partir d'une activation du muscle par le système nerveux central. En parallèle de cette activité mécanique, le muscle produit aussi une activité électrique elle aussi contrôlée par la même activation. Cette activité électrique peut être mesurée à la surface de la peau à l'aide d'électrode, ce signal enregistré par l'électrode se nomme le signa
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Liu, Mingyong. "Optimization of electromagnetic and acoustic performances of power transformers." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS256/document.

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Le travail présenté dans ce mémoire s’intéresse à la prédiction des vibrations d'un noyau de transformateur multicouche, constitué d'un assemblage de tôles ferromagnétiques. Le problème couplé magnéto-mécanique est résolu par une approche séquentielle progressive : la résolution magnétique est suivie d'une résolution mécanique. Un modèle multi-échelle simplifié 3D décrivant les anisotropies magnétiques et magnétostrictives, et considérant les non-linéarités magnétiques et de magnétostriction, est utilisé comme loi de comportement du matériau. La structure du noy
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Chen, Yun. "Mining Dynamic Recurrences in Nonlinear and Nonstationary Systems for Feature Extraction, Process Monitoring and Fault Diagnosis." Scholar Commons, 2016. http://scholarcommons.usf.edu/etd/6072.

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Real-time sensing brings the proliferation of big data that contains rich information of complex systems. It is well known that real-world systems show high levels of nonlinear and nonstationary behaviors in the presence of extraneous noise. This brings significant challenges for human experts to visually inspect the integrity and performance of complex systems from the collected data. My research goal is to develop innovative methodologies for modeling and optimizing complex systems, and create enabling technologies for real-world applications. Specifically, my research focuses on Mining Dyna
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Pereira, Danillo Roberto 1984. "Fitting 3D deformable biological models to microscope images = Alinhamento de modelos tridimensionais usando imagens de microscopia." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/275627.

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Orientador: Jorge Stolfi<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Computação<br>Made available in DSpace on 2018-08-23T12:30:57Z (GMT). No. of bitstreams: 1 Pereira_DanilloRoberto_D.pdf: 2771811 bytes, checksum: 6d5b092c08b5c011636be5fc2661e4a0 (MD5) Previous issue date: 2013<br>Resumo: Nesta tese descrevemos um algoritmo genérico (que denominamos MSFit) capaz de estimar a pose e as deformações de modelos 3D de estruturas biológicas (bactérias, células e etc.) em imagens obtidas por meio de microscópios óticos ou de varredura eletrônica. O algoritmo usa comparaçã
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Waldspurger, Irène. "Wavelet transform modulus : phase retrieval and scattering." Thesis, Paris, Ecole normale supérieure, 2015. http://www.theses.fr/2015ENSU0036/document.

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Les tâches qui consistent à comprendre automatiquement le contenu d’un signal naturel, comme une image ou un son, sont en général difficiles. En effet, dans leur représentation naïve, les signaux sont des objets compliqués, appartenant à des espaces de grande dimension. Représentés différemment, ils peuvent en revanche être plus faciles à interpréter. Cette thèse s’intéresse à une représentation fréquemment utilisée dans ce genre de situations, notamment pour analyser des signaux audio : le module de la transformée en ondelettes. Pour mieux comprendre son comportement, nous considérons, d’un p
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Koyeerath, Graham Danny. "Topology optimization in interfacial flows using the pseudopotential model." Electronic Thesis or Diss., Nantes Université, 2024. http://www.theses.fr/2024NANU4008.

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L'optimisation des systèmes et des processus est un exercice qui s'effectue en tenant compte de l'expérience et des connaissances de chacun. Nous explorons ici une approche mathématique pour optimiser les problèmes physiques en utilisant divers algorithmes d'optimisation. Dans cette thèse, l'objectif préliminaire de l'optimiseur est de modifier les caractéristiques d'écoulement du système en ajustant les forces capillaires. Cet objectif peut être atteint en modifiant l'un des deux ensembles de paramètres : (a) en introduisant un matériau solide mouillant (paramètre de niveau) ou (b) en changea
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Billy, Frédérique. "Modélisation mathématique multi-échelle de l'angiogenèse tumorale : analyse de la réponse tumorale aux traitements anti-angiogéniques." Phd thesis, Université Claude Bernard - Lyon I, 2009. http://tel.archives-ouvertes.fr/tel-00631513.

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Le cancer est l'une des principales causes de décès dans le monde. L'angiogenèse tumorale est le processus de formation de nouveaux vaisseaux sanguins à partir de vaisseaux préexistants. Une tumeur cancéreuse peut induire l'angiogenèse afin de disposer d'apports supplémentaires en oxygène et nutriments, indispensables à la poursuite de son développement. Cette thèse consiste en l'élaboration d'un modèle mathématique multi-échelle de l'angiogenèse tumorale. Ce modèle intègre les principaux mécanismes intervenant aux échelles tissulaire et moléculaire. Couplé à un modèle de croissance tumorale,
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Wenzel, Moritz. "Development of a Metamaterial-Based Foundation System for the Seismic Protection of Fuel Storage Tanks." Doctoral thesis, Università degli studi di Trento, 2020. http://hdl.handle.net/11572/256685.

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Metamaterials are typically described as materials with ’unusual’ wave propagation properties. Originally developed for electromagnetic waves, these materials have also spread into the field of acoustic wave guiding and cloaking, with the most relevant of these ’unusual’ properties, being the so called band-gap phenomenon. A band-gap signifies a frequency region where elastic waves cannot propagate through the material, which in principle, could be used to protect buildings from earthquakes. Based on this, two relevant concepts have been proposed in the field of seismic engineering, namely: me
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Wenzel, Moritz. "Development of a Metamaterial-Based Foundation System for the Seismic Protection of Fuel Storage Tanks." Doctoral thesis, Università degli studi di Trento, 2020. http://hdl.handle.net/11572/256685.

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Metamaterials are typically described as materials with ’unusual’ wave propagation properties. Originally developed for electromagnetic waves, these materials have also spread into the field of acoustic wave guiding and cloaking, with the most relevant of these ’unusual’ properties, being the so called band-gap phenomenon. A band-gap signifies a frequency region where elastic waves cannot propagate through the material, which in principle, could be used to protect buildings from earthquakes. Based on this, two relevant concepts have been proposed in the field of seismic engineering, namely: me
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Residori, Sara. "FABRICATION AND CHARACTERIZATION OF 3D PRINTED METALLIC OR NON-METALLIC GRAPHENE COMPOSITES." Doctoral thesis, Università degli studi di Trento, 2022. https://hdl.handle.net/11572/355324.

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Nature develops several materials with remarkable functional properties composed of comparatively simple base substances. Biological materials are often composites, which optime the conformation to their function. On the other hand, synthetic materials are designed a priori, structuring them according to the performance to be achieved. 3D printing manufacturing is the most direct method for specific component production and earmarks the sample with material and geometry designed ad-hoc for a defined purpose, starting from a biomimetic approach to functional structures. The technique has the a
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Zhu, Yan. "Rational design of plastic packaging for alcoholic beverages." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLA020.

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La perception des emballages alimentaires est passée d’utile à source majeure de contaminants dans les aliments et menace pour l’environnement. La substitution du verre par des con-tenants en plastiques recyclés ou biosourcés réduit l’impact environnemental des boissons embouteillées. La thèse a développé de nouveaux outils de simulation 3D et d’optimisation pour accélérer le prototypage des emballages éco-efficaces pour les boissons alcoolisées. La durée de conservation des boissons, la sécurité sanitaire des matériaux plastiques recyclés, les contraintes mécaniques, et la quantité de déchets
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Derou, Dominique. "Optimisation neuronale et régularisation multiéchelle auto-organisée pour la trajectographie de particules : application à l'analyse d'écoulements en mécanique des fluides." Grenoble INPG, 1995. http://www.theses.fr/1995INPG0146.

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Differentes techniques de traitement d'images, reunies sous l'appellation de velocimetrie par images de particules, sont utilisees pour extraire les caracteristiques d'ecoulements de mecanique des fluides. Avec l'emergence de nouvelles techniques de resolution de problemes combinatoires et de traitement d'images, il est possible d'aborder efficacement le probleme de velocimetrie sous un jour nouveau. Dans la presente etude, nous nous interessons aux deux points suivants: la restitution d'un champ de vitesse instantanee, a partir des images de visualisation d'ecoulements ensemences a l'aide de
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Eve, Thierry. "Optimisation decentralisee et coordonnee de la conduite de systemes electriques interconnectes." Paris 6, 1994. http://www.theses.fr/1994PA066569.

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Dans notre travail, l'optimisation de la conduite de systemes electriques interconnectes est envisagee sous l'angle de la resolution d'un grand programme lineaire dont la formulation complete est inaccessible. En effet, les donnees necessaires a la description du probleme sont reparties entre differents centres de decision qui n'echangent entre eux qu'un volume limite d'informations. Par ailleurs, chaque centre de decision souhaite conserver son autonomie, c'est-a-dire resoudre avec ses propres outils une version restreinte du probleme de base. En s'appuyant sur le contexte mathematique de la
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Gobé, Alexis. "Méthodes Galerkin discontinues pour la simulation de problèmes multiéchelles en nanophotonique et applications au piégeage de la lumière dans des cellules solaires." Thesis, Université Côte d'Azur, 2020. http://www.theses.fr/2020COAZ4011.

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L’objectif de cette thèse est l’étude numérique du piégeage de la lumière dans des cellules solaires nanostructurées. Le changement climatique est devenu une problématique majeure nécessitant une transition énergétique à court terme. Dans ce contexte, l'énergie solaire semble être une source énergétique idéale. Cette ressource est à la fois scalable à l’échelle planétaire et écologique. Afin de maximiser sa pénétration, des travaux visant à augmenter la quantité de lumière absorbée et à réduire les coûts liés à la conception des cellules sont nécessaires. Le piégeage de la lumière est une stra
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Rath, James Michael 1975. "Multiscale basis optimization for Darcy flow." Thesis, 2007. http://hdl.handle.net/2152/3977.

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Simulation of flow through a heterogeneous porous medium with fine-scale features can be computationally expensive if the flow is fully resolved. Coarsening the problem gives a faster approximation of the flow but loses some detail. We propose an algorithm that obtains the fully resolved approximation but only iterates on a sequence of coarsened problems. The sequence is chosen by optimizing the shapes of the coarse finite element basis functions. As a stand-alone method, the algorithm converges globally and monotonically with a quadratic asymptotic rate. Computational experience indicates the
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Li, Xiaohai. "Multiscale simulation and optimization of copper electrodeposition /." 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3290296.

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Thesis (Ph. D.)--University of Illinois at Urbana-Champaign, 2007.<br>Source: Dissertation Abstracts International, Volume: 68-11, Section: B, page: 7496. Advisers: Richard D. Braatz; Richard C. Alkire. Includes bibliographical references. Available on microfilm from Pro Quest Information and Learning.
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Raimondeau, Stephanie Marie. "Development, optimization, and reduction of hierarchical multiscale models." 2003. https://scholarworks.umass.edu/dissertations/AAI3078715.

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The objective of this dissertation is to develop various multiscale modeling methods for chemical reactors. This objective stems from the demand for more accurate and predictive reactor models or the need for miniaturization of materials. The wide disparity in scales encountered in practical industrial reactors requires a hierarchical approach with a different model for each scale along with methods for coupling these models. These multiscale models entail dynamic, bi-directional coupling of quantum information with molecular simulations and continuum deterministic reactor models. The feasibil
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Ngnotchouye, Jean Medard Techoukouegno. "Conservation laws models in networks and multiscale flow optimization." Thesis, 2011. http://hdl.handle.net/10413/7922.

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The flow of fluids in a network is of practical importance in gas, oil and water transport for industrial and domestic use. When the flow dynamics are understood, one may be interested in the control of the flow formulated as follows: given some fluid properties at a final time, can one determine the initial flow properties that lead to the desired flow properties? In this thesis, we first consider the flow of a multiphase gas, described by the drift flux model, in a network of pipes and that of water, modeled by the shallow water equations, in a network of rivers. These two models are systems
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Sun, Hao. "Development of Hierarchical Optimization-based Models for Multiscale Damage Detection." Thesis, 2014. https://doi.org/10.7916/D8GQ6W2J.

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In recent years, health monitoring of structure and infrastructure systems has become a valuable source of information for evaluating structural integrity, durability and reliability throughout the lifecycle of structures as well as ensuring optimal maintenance planning and operation. Important advances in sensor and computer technologies made possible to process a large amount of data, to extract the characteristic features of the signals, and to link those to the current structural conditions. In general, the process of data feature extraction relates to solving an inverse problem, in either
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(5930414), Tong Wu. "TOPOLOGY OPTIMIZATION OF MULTISCALE STRUCTURES COUPLING FLUID, THERMAL AND MECHANICAL ANALYSIS." Thesis, 2019.

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<div>The objective of this dissertation is to develop new methods in the areas of multiscale topology optimization, thermomechanical topology optimization including heat convection, and thermal-fluid topology optimization. The dissertation mainly focuses on developing five innovative topology optimization algorithms with respect to structure and multistructure coupling fluid, thermal and mechanical analysis, in order to solve customary design requirements. Most of algorithms are coded as in-house code in MATLAB.</div><div><br></div><div><div>In Chapter One, a brief introduction of topology opt
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DE, MAIO RAUL. "Multiscale methods for traffic flow on networks." Doctoral thesis, 2019. http://hdl.handle.net/11573/1239374.

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In this thesis we propose a model to describe traffic flows on network by the theory of measure-based equations. We first apply our approach to the initial/boundary-value problem for the measure-valued linear transport equation on a bounded interval, which is the prototype of an arc of the network. This simple case is the first step to build the solution of the respective linear problem on networks: we construct the global solution by gluing all the measure-valued solutions on the arcs by means of appropriate distribution rules at the vertices. The linear case is adopted to show the we
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"Measurement, optimization and multiscale modeling of silicon wafer bonding interface fracture resistance." Université catholique de Louvain, 2006. http://edoc.bib.ucl.ac.be:81/ETD-db/collection/available/BelnUcetd-10272006-203227/.

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Hu, Nan. "Advances in Multiscale Methods with Applications in Optimization, Uncertainty Quantification and Biomechanics." Thesis, 2016. https://doi.org/10.7916/D8FX79N8.

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Advances in multiscale methods are presented from two perspectives which address the issue of computational complexity of optimizing and inverse analyzing nonlinear composite materials and structures at multiple scales. The optimization algorithm provides several solutions to meet the enormous computational challenge of optimizing nonlinear structures at multiple scales including: (i) enhanced sampling procedure that provides superior performance of the well-known ant colony optimization algorithm, (ii) a mapping-based meshing of a representative volume element that unlike unstructured meshing
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Park, Han-Young. "A Hierarchical Multiscale Approach to History Matching and Optimization for Reservoir Management in Mature Fields." Thesis, 2012. http://hdl.handle.net/1969.1/ETD-TAMU-2012-08-11779.

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Reservoir management typically focuses on maximizing oil and gas recovery from a reservoir based on facts and information while minimizing capital and operating investments. Modern reservoir management uses history-matched simulation model to predict the range of recovery or to provide the economic assessment of different field development strategies. Geological models are becoming increasingly complex and more detailed with several hundred thousand to million cells, which include large sets of subsurface uncertainties. Current issues associated with history matching, therefore, involve extens
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Varshney, Amit. "Optimization and control of multiscale process systems using model reduction: application to thin-film growth." 2007. http://etda.libraries.psu.edu/theses/approved/WorldWideIndex/ETD-1967/index.html.

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Foderaro, Greg. "A Distributed Optimal Control Approach for Multi-agent Trajectory Optimization." Diss., 2013. http://hdl.handle.net/10161/8226.

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<p>This dissertation presents a novel distributed optimal control (DOC) problem formulation that is applicable to multiscale dynamical systems comprised of numerous interacting systems, or agents, that together give rise to coherent macroscopic behaviors, or coarse dynamics, that can be modeled by partial differential equations (PDEs) on larger spatial and time scales. The DOC methodology seeks to obtain optimal agent state and control trajectories by representing the system's performance as an integral cost function of the macroscopic state, which is optimized subject to the agents' dynamics
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Bauman, Paul Thomas 1980. "Adaptive multiscale modeling of polymeric materials using goal-oriented error estimation, Arlequin coupling, and goals algorithms." Thesis, 2008. http://hdl.handle.net/2152/3824.

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Scientific theories that explain how physical systems behave are described by mathematical models which provide the basis for computer simulations of events that occur in the physical universe. These models, being only mathematical characterizations of actual phenomena, are obviously subject to error because of the inherent limitations of all mathematical abstractions. In this work, new theory and methodologies are developed to quantify such modeling error in a special way that resolves a fundamental and standing issue: multiscale modeling, the development of models of events that transcend ma
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Liu, Kai. "Concurrent topology optimization of structures and materials." Thesis, 2013. http://hdl.handle.net/1805/3755.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Topology optimization allows designers to obtain lightweight structures considering the binary distribution of a solid material. The introduction of cellular material models in topology optimization allows designers to achieve significant weight reductions in structural applications. However, the traditional topology optimization method is challenged by the use of cellular materials. Furthermore, increased material savings and performance can be achieved if the material and the structure topologies are concurrently designed. Hence, m
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Reis, Marco Paulo Seabra. "Monitorização, modelação e melhoria de processos químicos : abordagem multiescala baseada em dados." Doctoral thesis, 2006. http://hdl.handle.net/10316/7375.

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Tese de doutoramento em Engenharia Química (Processos Químicos) apresentada à Faculdade de Ciências e Tecnologia da Univ. de Coimbra<br>Processes going on in modern chemical processing plants are typically very complex, and this complexity is also present in collected data, which contain the cumulative effect of many underlying phenomena and disturbances, presenting different patterns in the time/frequency domain. Such characteristics motivate the development and application of data-driven multiscale approaches to process analysis, with the ability of selectively analyzing the information
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