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Artykuły w czasopismach na temat „N-059”

Autor: Grafiati

Data publikacji: 29 lipca 2024

Data aktualizacji: 31 lipca 2025

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1

Smith, Heather L., Martin F. Sherman, Julie Sriken, Bradley T. Erford, Adriana Kipper-Smith, and Frances Niarhos. "Testing for Measurement Invariance of the Counseling Center Assessment of Psychological Symptoms–34 Scores With a University Sample." Journal of Mental Health Counseling 46, no. 2 (2024): 171–87. http://dx.doi.org/10.17744/mehc.46.2.05.

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This study expanded previous psychometric analyses to include gender and race using measurement invariance with the Counseling Center Assessment of Psychological Symptoms (CCAPS-34) on a large sample (n = 4,013) of students referred to a university counseling center. Internal consistency was demonstrated for all subscales with all αs and ωs ≥ .80. The seven-factor model provided a good to excellent fit for all participant subgroup responses. The total sample comparative fit index was .948, the root-mean-square error of approximation was .058 [.057, .059], and the standardized root-mean-square

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2

Marshall, J. Wb, K. J. Duffin, A. R. Green, and R. M. Ridley. "NXY-059, the free radical trapping nitrone-based agent, reduces hemiparesis and reduces grey and white matter damage after focal cerebral ischemia in monkeys." Stroke 32, suppl_1 (2001): 327. http://dx.doi.org/10.1161/str.32.suppl_1.327.

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60 There is little published evidence for protection of white matter with neuroprotective drugs in animal models of stroke, yet white matter protection may be important in achieving clinical efficacy. We have examined the effects of NXY-059, a nitrone-based free radical trapping agent, on long-term functional disability in a primate model of stroke. We also examined histopathological effects, including analyses of grey and white matter damage. Five minutes after unilateral permanent middle cerebral artery occlusion, marmosets received a 1 ml i.v. infusion of saline (n=5) or NXY-059 (28 mg/kg)

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Sydserff, S. G., A. R. Borrelli, and A. J. Cross. "The neuroprotective efficacy of NXY-059 in permanent MCAo in the rat: Dose response and therapeutic window." Stroke 32, suppl_1 (2001): 353. http://dx.doi.org/10.1161/str.32.suppl_1.353-a.

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P78 Introduction. NXY-059 (disodium 4-[(tert-butylimino)methyl] benzene-1,3-disulfonate N-oxide) is a nitrone with free radical trapping properties and is being developed for the treatment of acute ischemic stroke. NXY-059 possesses proven neuroprotective efficacy in rat transient models of middle cerebral artery occlusion (MCAo) (J Cereb Blood Flow Metab 1999;19:778–87), however its efficacy in permanent models of focal cerebral ischemia has not been as extensively tested. In the present study we have examined the efficacy of NXY-059 at three doses and further examined the therapeutic window

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4

Hainsworth, Atticus H., Nasrin Bhuiyan, and A. Richard Green. "The Nitrone Disodium 2,4-Sulphophenyl-N-Tert-Butylnitrone is Without Cytoprotective Effect on Sodium Nitroprusside-Induced Cell Death in N1E-115 Neuroblastoma Cells in vitro." Journal of Cerebral Blood Flow & Metabolism 28, no. 1 (2007): 24–28. http://dx.doi.org/10.1038/sj.jcbfm.9600517.

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Disodium 2,4-sulphophenyl- N-tert-butylnitrone (NXY-059) is a novel free radical-trapping compound that is neuroprotective in both rodent and primate models of acute ischaemic stroke. Neuroprotection in vitro by NXY-059 has not been reported previously, and we have now investigated whether such an effect can be detected using a simple cell culture model of neurotoxicity. Neuron-like cells of the neuroblastoma-derived clonal cell line N1E-115 were exposed to the free radical-generating agent sodium nitroprusside (SNP), which produced a concentration-dependent reduction in mitochondrial complex

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5

Kuroda, Satoshi, Ryoichi Tsuchidate, Maj-Lis Smith, Kirk R. Maples, and Bo K. Siesjö. "Neuroprotective Effects of a Novel Nitrone, NXY-059, after Transient Focal Cerebral Ischemia in the Rat." Journal of Cerebral Blood Flow & Metabolism 19, no. 7 (1999): 778–87. http://dx.doi.org/10.1097/00004647-199907000-00008.

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Recent results have demonstrated that the spin trapping agent α-phenyl- N- tert-butyl nitrone (PBN) reduces infarct volume in rats subjected to 2 hours of middle cerebral artery occlusion, even when given 1 to 3 hours after the start of recirculation. In the current study, the authors assessed the effect of NXY-059, a novel nitrone that is more soluble than PBN. Loading doses were given of 0.30, 3.0, or 30 mg · kg−1 followed by 0.30, 3.0, or 30 mg · kg−1 · h−1 for 24 or 48 hours. Dose–response studies showed that when treatment was begun 1 hour after recirculation, 0.30 mg · kg−1 had a small a

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6

Lara-Garrido, Adrián Salvador, Gloria Álvarez-Bernardo, and Ana Belén García-Berbén. "Validity and measurement invariance of the Modern Homonegativity Scale for students in the field of education." Anales de Psicología 40, no. 1 (2024): 85–94. http://dx.doi.org/10.6018/analesps.544141.

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The research aimed at analysing attitudes towards homosexuality recommends the use of instruments that can detect subtle aspects of discrimination against gay men and lesbian women. It also asserts that the measurement invariance of constructs is essential for valid comparisons between groups. The present study aims to validate the Modern Homonegativity Scale (MHS) in university students in the field of education (N = 1.283) with an age range of 17 to 49 years old (M = 2.88; SD = 3.02). In addition, we seek to examine the measurement invariance of the MHS in relation to certain sociodemographi

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7

Martins, Maurilio Lopes, Uelinton Manoel Pinto, Katharina Riedel, and Maria Cristina Dantas Vanetti. "Quorum Sensing and Spoilage Potential of Psychrotrophic Enterobacteriaceae Isolated from Milk." BioMed Research International 2018 (October 22, 2018): 1–13. http://dx.doi.org/10.1155/2018/2723157.

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The 16S rDNA of six psychrotrophic Enterobacteriaceae isolated from cold raw milk were sequenced and the isolate 039 was identified asPantoeasp., isolates 059, 068, and 071 were identified asHafnia alvei, 067 was identified asEnterobactersp., and 099 was identified asAeromonas hydrophila. They presented different spoilage potentials in milk withA. hydrophila099 being the most deteriorative. OnlyPantoeasp. 039 was not able to induce the quorum sensing monitor strains of acyl homoserine lactones (AHLs). ThehalIgene, which encodes the AHL synthase inH. alvei, was identified in the isolates 059, 0

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8

Luu, Britney, Mary Ellen Garcia, Katherine Bangen, Douglas Galasko, and Kelsey Thomas. "SUBJECTIVE COGNITIVE CONCERNS AND 5-YEAR NEUROPSYCHOLOGICAL TRAJECTORIES IN PARKINSON’S DISEASE." Innovation in Aging 7, Supplement_1 (2023): 974–75. http://dx.doi.org/10.1093/geroni/igad104.3131.

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Abstract Subjective cognitive concerns (SCC) are often associated with Alzheimer’s disease (AD)-related cognitive declines in cognitively unimpaired (CU) individuals. However, it is unknown whether the same is true for CU individuals with Parkinson’s disease (PD). Therefore, this study examined relationships between SCC and 5-year neuropsychological trajectories in CU individuals with newly-diagnosed PD (mean age=60.45 years; 35.2% female) in the Parkinson’s Progression Markers Initiative (PPMI) cohort. Participants were classified as having SCC (n=52) or no SCC (n=204) based on participant or

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9

Maria, DUCA, MUTU Ana, and CLAPCO Steliana. "GENOTIPAREA POPULAȚIILOR DE OROBANCHE CUMANA Wallr. CU MARCHERI MICROSATELIȚI SSR." STUDIA UNIVERSITATIS MOLDAVIAE Științe Reale și ale Naturii, no. 6(156) (2022): 17–25. https://doi.org/10.5281/zenodo.7442249.

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Lucrarea a vizat evaluarea diversității genetice în cadrul a 33 de populații de lupoaie (<em>Orobanche cumana</em> Wallr.) cu origine geografică diferită,<em> </em>prin genotiparea cu 14 marcheri microsateliți SSR. Majoritatea marcherilor (Ocum-052, Ocum-059, Ocum-070, Ocum-081, Ocum-087, Ocum-160, Ocum-196 și Ocum-197) au pus în evidență o diversitate accentuată atât la nivel inter-, intrapopulațional, cât și regional. În cadrul populațiilor de lupoaie investigate a fost relevată prezența a 153 de profile molecular-genetice și a 98 de alele. Lungimea se

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10

Wainberg, Zev A., Charles S. Fuchs, Josep Tabernero, et al. "Efficacy of pembrolizumab (pembro) monotherapy versus chemotherapy for PD-L1–positive (CPS ≥10) advanced G/GEJ cancer in the phase II KEYNOTE-059 (cohort 1) and phase III KEYNOTE-061 and KEYNOTE-062 studies." Journal of Clinical Oncology 38, no. 4_suppl (2020): 427. http://dx.doi.org/10.1200/jco.2020.38.4_suppl.427.

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427 Background: Pts with advanced gastric/gastroesophageal junction (G/GEJ) cancer received pembro monotherapy (200 mg Q3W) 3L+ in cohort 1 of KEYNOTE-059 (NCT02335411), 2L in KEYNOTE-061 (NCT02370498), or 1L in KEYNOTE-062 (NCT02494583). We present efficacy data for patients with PD-L1 combined positive score (CPS) ≥10 tumors in these trials. Methods: In study 059, 46 pts in cohort 1 with PD-L1 CPS ≥10 received pembro. In study 061, 108 pts with PD-L1 CPS ≥10 received pembro (n=53) or chemotherapy (chemo; n=55). In study 062, 182 pts with CPS ≥10 received pembro (n=92) or placebo + chemo (n=9

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11

Abu-Hilal, Maher, Said Al dafri, and Hashem Kilani. "Structure of Burnout among Omani Male and Female Teachers: Invariance of Structure across Gender." Journal of Educational and Psychological Studies [JEPS] 12, no. 4 (2018): 739–49. http://dx.doi.org/10.53543/jeps.vol12iss4pp739-749.

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Previous studies have supported the conceptualization that burnout consists of three aspects: emotional exhaustion, depersonalization and reduced personal accomplishment. When the proposed structure of burnout was tested in several studies, these three aspects were confirmed. However, several researchers found that depersonalization consists of two factors rather than one. The first factor is related to the job, while the second factor is related to students. The original factor structure (3-factor model) and the revised structure were tested by few Arab researchers. Recently, the Maslach Burn

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12

Abu-Hilal, Maher, Said Al dafri, and Hashem Kilani. "Structure of Burnout among Omani Male and Female Teachers: Invariance of Structure across Gender." Journal of Educational and Psychological Studies [JEPS] 12, no. 4 (2018): 739. http://dx.doi.org/10.24200/jeps.vol12iss4pp739-749.

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Previous studies have supported the conceptualization that burnout consists of three aspects: emotional exhaustion, depersonalization and reduced personal accomplishment. When the proposed structure of burnout was tested in several studies, these three aspects were confirmed. However, several researchers found that depersonalization consists of two factors rather than one. The first factor is related to the job, while the second factor is related to students. The original factor structure (3-factor model) and the revised structure were tested by few Arab researchers. Recently, the Maslach Burn

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13

Penner, Jacob, Raul Rupsingh, Matthew Smith, Jennie Wells, Michael Borrie, and Robert Bartha. "P2-059: Increased glutamate/N-acetylaspartate in the hippocampus after galantamine treatment in Alzheimer's disease." Alzheimer's & Dementia 4 (July 2008): T384. http://dx.doi.org/10.1016/j.jalz.2008.05.1132.

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14

Sawinski, Hannah, and Richard Dronskowski. "Synthesis and Crystal Structure of a “High-temperature” Phase of Li[H2NC(O)NH], the Missing Alkali-Metal Ureate." Zeitschrift für Naturforschung B 69, no. 6 (2014): 651–54. http://dx.doi.org/10.5560/znb.2014-4035.

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The new salt-like lithium ureate, LiCN2H3O, 1, was synthesized to round up the series of the recently published alkali-metal ureates. Single crystals of 1 were prepared similarly to the previously made ureates of Na-Cs in liquid ammonia. LiCN2H3O crystallizes in the monoclinic space group P21/n with a = 7:5770(9), b = 9:059(1), c = 13:046(2) Å, b = 98:896(2)°, V = 884:8(2)Å3, and Z = 12. The Li+ ions are coordinated by four ureate anions in a distorted tetrahedral manner. As expected, the deprotonation of the urea molecules is reflected by the shape of the anions with two different C-N bond le

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15

Kunter, Erdogan, Orhan Turken, Gokhan Kandemir, and Turgut Isitmangil. "Evaluation of Lung Cancer Patients With Skeletal Muscle Metastasis." Clinical Lung Cancer 10, no. 5 (2009): E10. http://dx.doi.org/10.3816/clc.2009.n.059.

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Chin, Kevin M., and Francine M. Foss. "Biologic Correlates of Response and Survival in Patients with Cutaneous T-Cell Lymphoma Treated with Denileukin Diftitox." Clinical Lymphoma and Myeloma 7, no. 3 (2006): 199–204. http://dx.doi.org/10.3816/clm.2006.n.059.

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Dimopoulos, Meletios A., Maria Roussou, Maria Gavriatopoulou, et al. "Reversibility of Renal Impairment in Patients With Multiple Myeloma Treated With Bortezomib-Based Regimens: Identification of Predictive Factors." Clinical Lymphoma and Myeloma 9, no. 4 (2009): 302–6. http://dx.doi.org/10.3816/clm.2009.n.059.

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Parikh, Sameer A., Hagop Kantarjian, Aaron Schimmer, et al. "Phase II Study of Obatoclax Mesylate (GX15-070), a Small-Molecule BCL-2 Family Antagonist, for Patients With Myelofibrosis." Clinical Lymphoma Myeloma and Leukemia 10, no. 4 (2010): 285–89. http://dx.doi.org/10.3816/clml.2010.n.059.

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Samiian, Laila, Bruce Daniel, and Irene Wapnir. "Resolution of Hypoalbuminemia After Excision of Malignant Phyllodes Tumor." Clinical Breast Cancer 7, no. 5 (2006): 411–12. http://dx.doi.org/10.3816/cbc.2006.n.059.

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Cianfrocca, Mary. "Overcoming Recurrence Risk: Extended Adjuvant Endocrine Therapy." Clinical Breast Cancer 8, no. 6 (2008): 493–500. http://dx.doi.org/10.3816/cbc.2008.n.059.

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Jensen, Anders Bonde, Christopher Wynne, Guillermo Ramirez, et al. "The Cathepsin K Inhibitor Odanacatib Suppresses Bone Resorption in Women With Breast Cancer and Established Bone Metastases: Results of a 4-Week, Double-Blind, Randomized, Controlled Trial." Clinical Breast Cancer 10, no. 6 (2010): 452–58. http://dx.doi.org/10.3816/cbc.2010.n.059.

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P., L. Vidal, de Moura J., Novo J., G. Penedo M., and Ortega M. "Image-to-Image Translation with Generative Adversarial Networks via Retinal Masks for Realistic Optical Coherence Tomography Imaging of Diabetic Macular Edema Disorders." Biomedical Signal Processing and Control 79 (June 7, 2023): 104098. https://doi.org/10.1016/j.bspc.2022.104098.

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This research was funded by Instituto de Salud Carlos III, Government of Spain, DTS18/00136 research project; Ministerio de Ciencia e Innovación y Universidades, Government of Spain, RTI2018-095894-B-I00 research project, Ayudas para la formación de profesorado universitario (FPU), grant ref. FPU18/02271; Ministerio de Ciencia e Innovación, Government of Spain through the research project with reference PID2019-108435RB-I00; Consellería de Cultura, Educación e Universidade, Xunta de Galicia, Spain, Grupos de Referencia Competitiva, grant ref. ED431C 2020/24 a

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Fiore, E., T. Rago, M. A. Provenzale, et al. "L-thyroxine-treated patients with nodular goiter have lower serum TSH and lower frequency of papillary thyroid cancer: results of a cross-sectional study on 27 914 patients." Endocrine-Related Cancer 17, no. 1 (2010): 231–39. http://dx.doi.org/10.1677/erc-09-0251.

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The risk of papillary thyroid cancer (PTC) is related to serum TSH, and the development of thyroid autonomy by reducing TSH levels decreases the frequency of PTC in patients with nodular goiter. Our aim was to investigate the effect of l-thyroxine (l-T4) on the frequency of PTC diagnosed by cytology in a large series of patients with nodular goiter untreated (n=20 055) or treated with l-T4 (n=7859). l-T4-treated patients with respect to untreated patients presented significantly lower serum TSH (median, interquartile range: 0.30 μU/ml, 0.08–0.62 μU/ml versus 0.70 μU/ml, 0.38–1.14 μU/ml; P<0

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ม่วงแก้ว, ญาดา, สถิรพร เชาวน์ชัย, กฤธยากาญจน์ โตพิทักษ์ та ปกรณ์ ประจันบาน. "การพัฒนาองค์ประกอบอภิทักษะของนิสิต/นักศึกษาครู". Journal of Education and Innovation 27, № 2 (2025): 151–64. https://doi.org/10.71185/jeiejournals.v27i2.278815.

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การวิจัยครั้งนี้มีวัตถุประสงค์เพื่อพัฒนาและตรวจสอบความสอดคล้องขององค์ประกอบอภิทักษะของนิสิต/นักศึกษาครู ตัวอย่างวิจัย คือ นิสิต/นักศึกษาครูของคณะครุศาสตร์/ศึกษาศาสตร์จาก 6 ภูมิภาคของมหาวิทยาลัยต่างๆ ในประเทศไทย จำนวน 238 คน ที่ได้จากการสุ่มแบบหลายขั้นตอน เก็บรวบรวมข้อมูลโดยใช้แบบวัดเชิงสถานการณ์แบบเลือกตอบ 5 ตัวเลือก จำนวน 18 ข้อ ครอบคลุมองค์ประกอบอภิทักษะทั้ง 3 ด้าน วิเคราะห์ข้อมูลโดยตรวจสอบคุณภาพแบบวัด พบว่า ข้อคำถามมีค่าดัชนี IOC ตั้งแต่ 0.60 – 1.00 มีค่าอำนาจจำแนกตั้งแต่ .315 - .549 มีค่าความเที่ยงเท่ากับ .822 และตรวจสอบความสอดคล้องของโมเดลการวัดอภิทักษะของนิสิต/นักศึกษาครูโดยใช้การวิเคราะ

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Fuchs, Charles S., Atsushi Ohtsu, Josep Tabernero, et al. "Pembrolizumab (MK-3475) plus 5-fluorouracil (5-FU) and cisplatin for first-line treatment of advanced gastric cancer: Preliminary safety data from KEYNOTE-059." Journal of Clinical Oncology 34, no. 4_suppl (2016): 161. http://dx.doi.org/10.1200/jco.2016.34.4_suppl.161.

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161 Background: Standard first-line treatment for advanced gastric cancer includes combination chemotherapy with a platinum agent and a fluoropyrimidine. The anti–PD-1 humanized monoclonal antibody pembrolizumab (pembro) has shown promising antitumor activity as monotherapy in patients (pts) with advanced gastric cancer. We report preliminary safety data for pts with advanced gastric cancer treated with pembro + cisplatin and 5-FU in the multicohort, phase 2 KEYNOTE-059 study (NCT02335411). Methods: Eligible pts were aged ≥ 18 y and had HER2– relapsed or metastatic gastric or gastroesophageal

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Vojtěchovský, Jaroslav, Jindřich Hašek, Jiří Ječný, and Karel Huml. "The structure of 1,2,4,4,6-pentaphenyl-1,4-dihydropyridine." Collection of Czechoslovak Chemical Communications 55, no. 8 (1990): 2059–65. http://dx.doi.org/10.1135/cccc19902059.

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Title compound is triclinic, Mr = 461.60; P1, a = 9.158(1), b = 16.062(3), c = 19.472(3) Å, α = 110.69(1)°, β = 89.70(1)°, γ = 103.17(1)°, V = 2 600(1) Å3, Z = 4, Do = 1.15(3), Dc = 1.179(1) Mg m-3, λ(CuKα) = 1.5418 Å, μ = 0.509 mm-1, F(000) = 976 K, R = 0.040 for 8 059 unique observed reflections. Both symmetrically independent molecules show a different geometry of the 1,4-dihydropyridine ring: either the boat conformation with apexes C(sp3), N and boat angles 14.7(3)° and 10.3(2)° respectively, or the planar conformation. The conformation has been compared with similar dihydropyridines obta

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Gromko, Joyce Eastlund, and Allison Smith Poorman. "The Effect of Music Training on Preschoolers' Spatial-Temporal Task Performance." Journal of Research in Music Education 46, no. 2 (1998): 173–81. http://dx.doi.org/10.2307/3345621.

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The purpose of this study was to investigate the effect of music training on preschoolers' Performance IQ (Wechsler Preschool and Primary Intelligence Scale-Revised, 1989). Preschoolers in the treatment group (N = 15) met weekly from October 1996 through April 1997. A Mann-Whitney test on Performance IQ (scaled) gain scores by group yielded U = 67, p =.059; a Mann-Whitney test on Performance IQ (raw) gain scores by group yielded U = 65, p =.049. Regressions of IQ gain scores on age showed significantly less gain for older children in the control group (N = 15). A regression analysis showed tha

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Haupt, Matteo, Stefan T. Gerner, Mathias Bähr, and Thorsten R. Doeppner. "Quest for Quality in Translational Stroke Research—A New Dawn for Neuroprotection?" International Journal of Molecular Sciences 23, no. 10 (2022): 5381. http://dx.doi.org/10.3390/ijms23105381.

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Despite tremendous progress in modern-day stroke therapy, ischemic stroke remains a disease associated with a high socioeconomic burden in industrialized countries. In light of demographic change, these health care costs are expected to increase even further. The current causal therapeutic treatment paradigms focus on successful thrombolysis or thrombectomy, but only a fraction of patients qualify for these recanalization therapies because of therapeutic time window restrictions or contraindications. Hence, adjuvant therapeutic concepts such as neuroprotection are urgently needed. A bench-to-b

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Juárez-García, Dehisy Marisol, Mónica Beatriz Vázquez-Esseso, Lizette Gálvez-Hernández, Jorge Bazan, and Sébastien Simard. "Fear of cancer recurrence inventory (FCRI) in Spanish: validation in Mexican women with breast cancer." Anales de Psicología 40, no. 3 (2024): 355–63. http://dx.doi.org/10.6018/analesps.590721.

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Background/Objective. The Fear Cancer Recurrence Inventory (FCRI) evaluates fear cancer recurrence multidimensionally and proposes a clinical cutoff point. However, there has yet to be a translated Spanish version of the FCRI to date. This study aims to evaluate the psychometric properties of the Spanish version of the FRCI in women who completed primary treatment for breast cancer. Material and Methods. Recommendations of the International Test Commission were followed for cultural adaptation. Two hundred sixty-seven women who completed primary treatment for breast cancer participated in and

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P., L. Vidal, de Moura J., Novo J., and Ortega M. "Multivendor fully-automatic uncertainty management approaches for the intuitive representation of DME fluid accumulations in OCT images." Medical & Biological Engineering & Computing 61 (June 7, 2023): 1209–24. https://doi.org/10.1007/s11517-022-02765-z.

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Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. Funding for Open Access charge: Universidade da Coruña/CISUG. This research was funded by Instituto de Salud Carlos III, Government of Spain, DTS18/00136 research project; Ministerio de Ciencia e Innovación y Universidades, Government of Spain, RTI2018-095894-B-I00 research project, Ayudas para la formación de profesorado universitario (FPU), grant ref. FPU18/02271; Ministerio de Ciencia e Innovación, Government of Spain through the research projects PID2019-108435RB-I00, PDC2022-13

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Avril, M. F., S. Aamdal, J. J. Grob, et al. "Fotemustine Compared With Dacarbazine in Patients With Disseminated Malignant Melanoma: A Phase III Study." Journal of Clinical Oncology 22, no. 6 (2004): 1118–25. http://dx.doi.org/10.1200/jco.2004.04.165.

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Purpose To compare fotemustine and dacarbazine (DTIC) in terms of overall response rate (ORR) as primary end-point and overall survival, duration of responses, time to progression, time to occurrence of brain metastases (BM), and to assess safety and quality of life in patients with disseminated cutaneous melanoma. Patients and Methods Patients received either intravenous fotemustine 100 mg/m2 weekly for 3 weeks or DTIC 250 mg/m2/d for 5 consecutive days every 4 weeks (two cycles). Nonprogressive patients received a maintenance treatment every 4 weeks (fotemustine 100 mg/m2 or DTIC 250 mg/m2 f

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Kampen, Gita T., Susan Stafford, Tetsuya Adachi, et al. "Eotaxin induces degranulation and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen-activated protein kinases." Blood 95, no. 6 (2000): 1911–17. http://dx.doi.org/10.1182/blood.v95.6.1911.

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Abstract Eotaxin and other CC chemokines acting via CC chemokine receptor-3 (CCR3) are believed to play an integral role in the development of eosinophilic inflammation in asthma and allergic inflammatory diseases. However, little is known about the intracellular events following agonist binding to CCR3 and the relationship of these events to the functional response of the cell. The objectives of this study were to investigate CCR3-mediated activation of the mitogen-activated protein (MAP) kinases extracellular signal-regulated kinase-2 (ERK2), p38, and c-jun N-terminal kinase (JNK) in eosinop

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Chatzisarantis, Nikos L. D., and Martin S. Hagger. "Effects of a Brief Intervention Based on the Theory of Planned Behavior on Leisure-Time Physical Activity Participation." Journal of Sport and Exercise Psychology 27, no. 4 (2005): 470–87. http://dx.doi.org/10.1123/jsep.27.4.470.

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Two persuasive communications were developed to assess the utility of an intervention based on the Theory of Planned Behavior in promoting physical activity attitudes, intentions, and behavior. One persuasive communication targeted modal salient behavioral beliefs (salient belief condition) while the other persuasive communication targeted nonsalient behavioral beliefs (nonsalient belief condition). Results of an intervention study conducted on young people (N = 83, mean age 14.60 yrs, SD = .47) indicated that participants who were presented with the persuasive message targeting modal salient

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Naranjo, Eduardo Jorge, and Eduardo Espinoza Medinilla. "Los mamíferos de la reserva ecológica Huitepec, Chiapas, México." Revista Mexicana de Mastozoología (Nueva Epoca) 5, no. 1 (2001): 58. http://dx.doi.org/10.22201/ie.20074484e.2001.5.1.97.

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Resumen: En este trabajo presentamos un listado de mamíferos silvestres de la Reserva Ecológica Huitepec (136 ha), ubicada en el municipio de San Cristóbal de Las Casas, en los altos de Chiapas, México. Entre 1991 y 1998 encontramos 40 especies de mamíferos pertenecientes a 15 familias y 7 órdenes. Los órdenes con mayor número de especies fueron Rodentia (n=17 especies) y Chiroptera (n=11 especies). Dos de las especies presentes en el área de estudio ( Sorex stizodon y Preomyscus zarhynchus) son endémicas de México y Guatemala, éstas dos, más otras cinco especies se encuentran en algún estatus

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Nyman, Samuel R., and Lucy Yardley. "Web-Site-Based Tailored Advice to Promote Strength and Balance Training: An Experimental Evaluation." Journal of Aging and Physical Activity 17, no. 2 (2009): 210–22. http://dx.doi.org/10.1123/japa.17.2.210.

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This study evaluated a Web site providing tailored advice to encourage older people to undertake strength and balance training (SBT). Adults age 60–88 (N = 302) were randomized to read either generic advice or advice tailored to their self-perceived balance problems and activity preferences. Between-groups differences in attitudes toward SBT after reading the advice did not quite reach significance (p = .059), but the tailored group reported higher ratings than the generic group that the advice was personally relevant (p = .017) and that the activities would be good for them (p = .047). Within

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Wilkerson, J. Michael, Jayson Michael Rhoton, Dennis Li, et al. "Information, Motivation, and Self-Efficacy Among Men Who Have Sex With Men and Transgender Women in the State of Maharashtra, India." Health Education & Behavior 46, no. 2 (2018): 304–11. http://dx.doi.org/10.1177/1090198118796880.

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Background. India’s National AIDS Control Programme calls for, among other things, targeted behavioral interventions that address determinants contributing to new infections among men who have sex with men (MSM) and hijras (transgender women). Aim. To determine if the information–motivation–behavioral skills model was transferable to an Indian context. Methods. We recruited 442 MSM and 7 hijras into an online cross-sectional study that asked questions about condom use knowledge, motivation, self-efficacy, and sexual behavior. Structural equation modeling was used to test the overall informatio

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Naranjo, Eduardo Jorge, and Eduardo Espinoza Medinilla. "Los mamíferos de la reserva ecológica Huitepec, Chiapas, México." Revista Mexicana de Mastozoología (Nueva Epoca) 5, no. 1 (2001): 58. https://doi.org/10.5281/zenodo.13440535.

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(Uploaded by Plazi for the Bat Literature Project) We present a checklist of the mammals found in Huitepec Ecological Reserve, located in the municipality of San Cristóbal de Las Casas, Chiapas, México. Between 1991 and 1998 we found 40 mammal species of 15 families and 7 orders. The most specious mammalian orders in the study area were Rodentia (n=17 species), and Chiroptera (n=11 species). Two of the species (Sorex stizodon and Peromyscus zarhynchus) present in the Huitepec Reserve are endemic of México and Guatemala. These and other five species are enlisted in the Mexican Norm of Endangere

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Naranjo, Eduardo Jorge, and Eduardo Espinoza Medinilla. "Los mamíferos de la reserva ecológica Huitepec, Chiapas, México." Revista Mexicana de Mastozoología (Nueva Epoca) 5, no. 1 (2001): 58. https://doi.org/10.5281/zenodo.13440535.

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(Uploaded by Plazi for the Bat Literature Project) We present a checklist of the mammals found in Huitepec Ecological Reserve, located in the municipality of San Cristóbal de Las Casas, Chiapas, México. Between 1991 and 1998 we found 40 mammal species of 15 families and 7 orders. The most specious mammalian orders in the study area were Rodentia (n=17 species), and Chiroptera (n=11 species). Two of the species (Sorex stizodon and Peromyscus zarhynchus) present in the Huitepec Reserve are endemic of México and Guatemala. These and other five species are enlisted in the Mexican Norm of Endangere

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Naranjo, Eduardo Jorge, and Eduardo Espinoza Medinilla. "Los mamíferos de la reserva ecológica Huitepec, Chiapas, México." Revista Mexicana de Mastozoología (Nueva Epoca) 5, no. 1 (2001): 58. https://doi.org/10.5281/zenodo.13440535.

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(Uploaded by Plazi for the Bat Literature Project) We present a checklist of the mammals found in Huitepec Ecological Reserve, located in the municipality of San Cristóbal de Las Casas, Chiapas, México. Between 1991 and 1998 we found 40 mammal species of 15 families and 7 orders. The most specious mammalian orders in the study area were Rodentia (n=17 species), and Chiroptera (n=11 species). Two of the species (Sorex stizodon and Peromyscus zarhynchus) present in the Huitepec Reserve are endemic of México and Guatemala. These and other five species are enlisted in the Mexican Norm of Endangere

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40

Naranjo, Eduardo Jorge, and Eduardo Espinoza Medinilla. "Los mamíferos de la reserva ecológica Huitepec, Chiapas, México." Revista Mexicana de Mastozoología (Nueva Epoca) 5, no. 1 (2001): 58. https://doi.org/10.5281/zenodo.13440535.

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(Uploaded by Plazi for the Bat Literature Project) We present a checklist of the mammals found in Huitepec Ecological Reserve, located in the municipality of San Cristóbal de Las Casas, Chiapas, México. Between 1991 and 1998 we found 40 mammal species of 15 families and 7 orders. The most specious mammalian orders in the study area were Rodentia (n=17 species), and Chiroptera (n=11 species). Two of the species (Sorex stizodon and Peromyscus zarhynchus) present in the Huitepec Reserve are endemic of México and Guatemala. These and other five species are enlisted in the Mexican Norm of Endangere

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Naranjo, Eduardo Jorge, and Eduardo Espinoza Medinilla. "Los mamíferos de la reserva ecológica Huitepec, Chiapas, México." Revista Mexicana de Mastozoología (Nueva Epoca) 5, no. 1 (2001): 58. https://doi.org/10.5281/zenodo.13440535.

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(Uploaded by Plazi for the Bat Literature Project) We present a checklist of the mammals found in Huitepec Ecological Reserve, located in the municipality of San Cristóbal de Las Casas, Chiapas, México. Between 1991 and 1998 we found 40 mammal species of 15 families and 7 orders. The most specious mammalian orders in the study area were Rodentia (n=17 species), and Chiroptera (n=11 species). Two of the species (Sorex stizodon and Peromyscus zarhynchus) present in the Huitepec Reserve are endemic of México and Guatemala. These and other five species are enlisted in the Mexican Norm of Endangere

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Lerner, Bart S., and Edwin A. Locke. "The Effects of Goal Setting, Self-Efficacy, Competition, and Personal Traits on the Performance of an Endurance Task." Journal of Sport and Exercise Psychology 17, no. 2 (1995): 138–52. http://dx.doi.org/10.1123/jsep.17.2.138.

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This study investigated the effects of goal setting, self-efficacy, competition, and personality on the performance of a sit-up task. Prior to testing, participants were administered the Sport Orientation Questionnaire (SOQ; Gill & Deeter, 1988). Using a 2 × 2 + 1 design, 60 participants were randomly assigned to one of four conditions: (a) competition, medium goal; (b) competition, high goal; (c) no competition, medium goal; and (d) no competition, high goal. A fifth group from the same population (n = 15) was added and served as the do-best comparison group. The main effect of goal level

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Mezcua-Hidalgo, Alberto, Alberto Ruiz-Ariza, Sara Suárez-Manzano, and Emilio J. Martínez-López. "48-Hour Effects of Monitored Cooperative High-Intensity Interval Training on Adolescent Cognitive Functioning." Perceptual and Motor Skills 126, no. 2 (2019): 202–22. http://dx.doi.org/10.1177/0031512518825197.

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Physical activity has been positively related to better cognitive performance though the effects of varied exercise type and intensity and the duration of cognitive benefits are unclear. This study analyzed the effect of 16 minutes of monitored cooperative high-intensity interval training (monitored C-HIIT) at the start of the school day, on various cognitive variables over the next 24–48 hours. We randomly assigned 158 participants either to a control group ( n = 81) that engaged only in static stretching or to an experimental group ( n = 77) that performed monitored C-HIIT. We assessed cogni

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Rodríguez-Ruiz, Rodolfo, Rocío Ramírez Barrios, Beatriz Pereyra Cortés, Javier Bailón Miranda, Carlos Sánchez Castro, and Octavio Monroy-Vilchis. "A visit to the Mountain of Guerrero; first records of medium and large mammals in Atlixtac, Guerrero, México." Therya notes 4, no. 3 (2023): 157–62. http://dx.doi.org/10.12933/therya_notes-23-123.

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El estado de Guerrero es un área importante por su alta diversidad de mamíferos. Sin embargo, pocos estudios documentan esta diversidad de mamíferos en el estado. Debido a lo anterior, en este estudio se analizó la diversidad de mamíferos terrestres la región de Montaña de Atlixtac, Guerrero. Durante septiembre 2021 a marzo 2022 se visitó la comunidad de Atlixtac, Guerrero, se colocaron cámaras-trampa y se realizaron recorridos. La información obtenida se organizó y se analizó la abundancia y la diversidad. Se registraron 15 especies distribuidas en 10 familias; de éstas, 2 especies se encuent

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SOUSA, JÔNATAS RAULINO MARQUES DE, HANS RAJ GHEYI, MARCOS ERIC BARBOSA BRITO, DIEGO AZEVEDO XAVIER, and GUILHERME DE FREITAS FURTADO. "IMPACT OF SALINE CONDITIONS AND NITROGEN FERTILIZATION ON CITRUS PRODUCTION AND GAS EXCHANGES." Revista Caatinga 29, no. 2 (2016): 415–24. http://dx.doi.org/10.1590/1983-21252016v29n218rc.

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ABSTRACT: In two simultaneous experiments, we evaluated the impact of brackish irrigation water and nitrogen (N) fertilization on the production of citrus (scion-rootstock combinations) and its associated gas exchanges. These experiments were conducted at the Campus of Federal University of Campina Grande, Brazil in a protected environment (shade screens on the sides) using drainage lysimeters. Experiment I used a randomized block design (3 replicates), in a 5 × 3 factorial arrangement, corresponding to five water salinity levels (0.6, 1.2, 1.8, 2.4, and 3.0 dS m-1) and three scion-rootstock c

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Barão-Nóbrega, José António L., Pedro E. Nahuat-Cervera, Ignazio Avella, et al. "Herpetological diversity in Calakmul, Campeche, Mexico: species list with new distribution notes." Revista Mexicana de Biodiversidad 93 (November 4, 2022): e933927. http://dx.doi.org/10.22201/ib.20078706e.2022.93.3927.

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The herpetofauna occurring in the Selva Maya is one of the richest assemblages in the Americas. We herein provide an updated list of herpetofauna species for the Calakmul region, located in the southern Yucatán Peninsula, Campeche, Mexico. This species list was compiled considering the results of herpetological surveys conducted between 2015-2019 in the Calakmul Biosphere Reserve, information gathered from previous literature, and sighting records from the website iNaturalist. All this information combined resulted in the identification of 109 species, 23 amphibians and 86 reptiles, belonging

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Chao, Joseph, Charles S. Fuchs, Kohei Shitara, et al. "Pembrolizumab (pembro) in microsatellite instability-high (MSI-H) advanced gastric/gastroesophageal junction (G/GEJ) cancer by line of therapy." Journal of Clinical Oncology 38, no. 4_suppl (2020): 430. http://dx.doi.org/10.1200/jco.2020.38.4_suppl.430.

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430 Background: Pembro has demonstrated promising antitumor activity in patients (pts) with advanced G/GEJ cancer with PD-L1 CPS ≥1 and CPS ≥10 irrespective of MSI-H status. Here, we examine the antitumor activity of pembro monotherapy vs chemo in pts with MSI-H, advanced G/GEJ cancer in KEYNOTE (KN)-059 (NCT02335411), KN061 (NCT02370498), and KN062 (NCT02494583). Methods: Eligible pts with advanced G/GEJ cancer with ≥2 prior therapies (KN059 cohort 1; 3L+), 1 prior therapy (KN061; 2L), or no prior therapy (KN062; 1L) were enrolled. In KN059 cohort 1, pts received pembro only. In KN061 pts wer

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Granda-Vera, Juan, Inmaculada Alemany-Arrebola, and Nahum Aguilar-Garcia. "Gender and its Relationship with the Practice of Physical Activity and Sport." Apunts Educación Física y Deporte 132, no. 2 (2018): 123–41. https://doi.org/10.5672/apunts.2014-0983.es.(2018/2).132.09.

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  El objetivo de este estudio es diseñar un instrumento de medición de los estereotipos de género en la actividad física y el deporte de los niños y adolescentes españoles. Para este propósito, un cuestionario fue entregado a 593 alumnos de edades entre 9 a 13. Este cuestionario <em>ad hoc </em>consta de 24 ítems agrupados en 5 dimensiones. Tanto la fiabilidad como la validez se analizaron mediante modelos de ecuaciones estructurales con el <em>software </em>LISREL 8.8. El valor de α de Cronbach fue de 0.899 y el análisi

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Hyun, Myung Sun, Hyue Yong Kim, Kyoung A. Nam, Sun Hee Yun, Hyun Aha Lee, and Ja Hee Chu. "The Effects of the Professional Support Group on Self Efficacy and Burden of the Family Members with a Schizophrenic Patient." Journal of Korean Academy of psychiatric and Mental Health Nursing 13, no. 2 (2004): 135–45. http://dx.doi.org/10.12934/jkpmhn.2004.13.2.135.

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Purpose: This study examined the effects of the professional support group on self-efficacy and burden of the family members with a schizophrenic patient. Methods: This study used a non-equivalent control group pre-post design. The data was collected from April, 2002 to December, 2002. The subjects consisted of 21 family members. The experimental group(n=l 1) participated in a support group that consisted of 3 sessions(3-week period); the control group(n=10) did not participate in. To examine the effects of the professional support group, self-efficacy and burden of the family were measured be

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Fogarasi, Erzsébet, Mircea Dumitru Croitoru, Ibolya Fülöp, and Daniela-Lucia Muntean. "Is the Oxidative Stress Really a Disease?" Acta Medica Marisiensis 62, no. 1 (2016): 112–20. http://dx.doi.org/10.1515/amma-2015-0070.

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AbstractOxidative stress is an imbalance between free radicals or other reactive species and the antioxidant activity of the organism. Oxidative stress can induce several illnesses such as cardiovascular disease, neurodegenerative disorders, diabetes, cancer, Alzheimer and Parkinson. The biomarkers of oxidative stress are used to test oxidative injury of biomolecules. The indicators of lipid peroxidation (malondialdehyde, 4-hydroxy- 2-nonenal, 2-propenal, isoprostanes), of protein oxidation (carbonylated proteins, tyrosine derivatives), of oxidative damage of DNA, and other biomarkers (glutath

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