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Rozprawy doktorskie na temat „Neurophysiology”

Autor: Grafiati
Data publikacji: 4 czerwca 2021
Data aktualizacji: 25 lipca 2025

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1

Proudfoot, Malcolm. "Cortical neurophysiology of ALS." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:5b8673f7-8eb2-4bf2-b3b8-d901fa134007.

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The experiments described in this thesis aimed to investigate the neurophysiological consequences, at the cortical level, of the neurodegenerative condition, amyotrophic lateral sclerosis (ALS). A principle tenet of this study was that ALS is, first and foremost, a disorder of the cortical motor system, the precise pathological mechanisms of which remain incompletely understood. Furthermore, the degree to which neurodegeneration can be evidenced before the onset of symptoms is thus far uncertain, and the optimal means by which to measure therapeutic response has yet to be determined. Chapter 1
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Ni, Mhuircheartaigh Roisin Judith. "The neurophysiology of sedation." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:5097d3ca-5f5b-4b37-b7bd-abeb10ec196d.

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We recognise consciousness in ourselves and in those around us. Consciousness is the essence of our existence, who and what we are, but we are willing and able to let go of it daily during sleep, which we welcome and associate with rest, recovery and well being, knowing that consciousness will return reliably, when we are ready. Yet we cannot define this thing or process which makes us "us". We do not understand how it is constructed from the activity in our brains, how it is deconstructed by sleep, drugs or disease, or how it can be reconstructed by waking or recovery. Our ignorance renders u
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3

Galer, Sophie. "Impact de l'activité épileptique interictale sur le traitement cognitif: approche neurophysiologique et comportementale." Doctoral thesis, Universite Libre de Bruxelles, 2013. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/241299.

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Henrikson, Sindre. "The neurophysiology of stereoscopic vision." Thesis, University of Newcastle upon Tyne, 2018. http://hdl.handle.net/10443/4122.

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Many animals are able to perceive stereoscopic depth owing to the disparity information that arises from the left and right eyes' horizontal displacement on the head. The initial computation of disparity happens in primary visual cortex (V1) and is largely considered to be a correlation-based computation. In other words, the computational role of V1 as it pertains to stereoscopic vision can be seen to roughly perform a binocular cross-correlation between the images of the left and right eyes. This view is based on the unique success of a correlation-based model of disparity-selective cells { t
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Atherton, Jeremy Francis. "Neurophysiology of the subthalamic nucleus." Thesis, University of Edinburgh, 2001. http://hdl.handle.net/1842/29793.

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Possibly as many as half the neurones in the STN have an axon collateral with branches off<i> </i>from the main axon and reinnervates the nucleus. This suggests that rather than working autonomously as was previously thought, the neurones of the STN can operate together as a network. Computer models of the STN showed that the level of interconnectivity within the STN would be huge, even if each axon collateral only contacted a small number of the total neurones with dendritic fields that overlapped with it. A network model showed that such a system was capable of switch-like behaviour. At low
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6

Hallam, Glyn P. "The neurophysiology of emotion regulation." Thesis, University of Sheffield, 2013. http://etheses.whiterose.ac.uk/4732/.

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Herrero, Jose Luis. "Neurophysiology and neuropharmacology of visual attention." Thesis, University of Newcastle Upon Tyne, 2011. http://hdl.handle.net/10443/1166.

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There is ample evidence that attention to stimuli can facilitate perception under different experimental tasks. For example, human observers are faster and more accurate at detecting an object in a visual scene when they know in advance its location, motion or colour. Previous electrophysiological studies on attentional modulation have characterized the effects of attention on firing rates and oscillatory activity. They have also studied how attention can change basic neuronal integration properties, such as the size of the classical receptive field or its summation area. However, the cellular
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8

Watson, Alison. "The neurophysiology of human placebo analgesia." Thesis, University of Manchester, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499914.

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9

Baker, D. J. "The clinical neurophysiology of organophosphate poisoning." Thesis, University of Southampton, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259652.

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10

Bramon, Bosch Elvira. "Neurophysiology of schizophrenia : a family study." Thesis, King's College London (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.421061.

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11

Reeve, James Edward. "Functional dyes as tools for neurophysiology." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:8d8e7fa1-0f1d-4ff5-9f90-6915b15c1ad4.

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The aim of the project described in this thesis is to synthesise new functional molecules which interact with light for neurophysiological applications. In particular, I describe a family of amphiphilic porphyrins with large first hyperpolarisabilities which are used as SHG contrast agents and voltage-sensitive probes. In addition I detail a methodological microscopy tool and a novel caged form of a neuronal ion-channel antagonist. Chapter 1 introduces the key concepts underlying the use of dyes as SHG contrast agents. In particular it focuses on aspects of molecular design, covering both the
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12

Norman, Olivia Rose. "Optogenetic Tools for In-Vitro Neurophysiology." University of Toledo / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1408643520.

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13

Kovanis, Panagiotis. "Neurophysiology underlying neuroimaging of cortical function." Thesis, Cardiff University, 2014. http://orca.cf.ac.uk/74565/.

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The aim of this study was to shed light on some of the neurophysiological mechanisms behind visual perception and specifically look into feedback processes that may be taking place during visual processing and also inhibition processes of the visual cortex. The oblique effect is a preference of the visual system for cardinal orientations rather than oblique ones. A recent MEG study (Koelewijn, et al. 2011) finds in V1 an initial inverse oblique effect (80 msec from stim onset) which however later (120msec from stimulus onset) showed a trend towards the classical oblique effect and feedback pro
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14

Lewi, Jeremy. "Sequential optimal design of neurophysiology experiments." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/28201.

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Thesis (M. S.)--Biomedical Engineering, Georgia Institute of Technology, 2009.<br>Committee Co-Chair: Butera, Robert; Committee Co-Chair: Paninski, Liam; Committee Member: Isbell, Charles; Committee Member: Rozell, Chris; Committee Member: Stanley, Garrett; Committee Member: Vidakovic, Brani.
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15

Ficarella, Stefania. "The neurophysiology of internally-driven actions." Doctoral thesis, Università degli studi di Trento, 2015. https://hdl.handle.net/11572/369076.

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Acting in the world in a way that matches our goals, overriding impulses, is one of the first abilities that we must learn while growing up. We often change the course of our actions because of external influences or because we simply “change our mind†. As John H. Patterson said, “Only fools and dead men don't change their minds. Fools won’t. Dead men can’t†. An important distinction must first be made between the impact of internal and external sources on action decisions, and the first part of the introduction will be devoted to this topic. In the second part, I will discuss the
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16

Ficarella, Stefania. "The neurophysiology of internally-driven actions." Doctoral thesis, University of Trento, 2015. http://eprints-phd.biblio.unitn.it/1450/1/TesiFicarella2015.pdf.

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Acting in the world in a way that matches our goals, overriding impulses, is one of the first abilities that we must learn while growing up. We often change the course of our actions because of external influences or because we simply “change our mind”. As John H. Patterson said, “Only fools and dead men don't change their minds. Fools won’t. Dead men can’t”. An important distinction must first be made between the impact of internal and external sources on action decisions, and the first part of the introduction will be devoted to this topic. In the second part, I will discuss the topic of i
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17

Galley, Peter Timothy. "The development of enzyme electrodes for neurophysiology." Thesis, Imperial College London, 1991. http://hdl.handle.net/10044/1/46777.

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18

Kwiatkowski, Jonna. "Individual Differences in the Neurophysiology of Creativity." Fogler Library, University of Maine, 2002. http://www.library.umaine.edu/theses/pdf/KwiatkowskiJ2002.pdf.

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19

Fois, Alessandro Francesco. "Tremor classification and measurement: insights from neurophysiology." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/29841.

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Tremor is a common problem, affecting perhaps 1% of the human population, and often manifests in the upper limbs where it can interfere with hand function and cause social embarrassment. The assessment and classification of human tremor into diagnostic categories remains predominantly clinical, leading to inter-observer inconsistencies that blur the diagnostic labels used in research and clinical practice and hamper both endeavours. In this thesis, I explore the use of neurophysiological techniques in a series of related studies to provide an objective method of measuring tremor and gaining in
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20

Goonawardena, Anushka V. "Cannabinoid effects on hippocampal neurophysiology and mnemonic processing." Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources. Restricted: no access until Mar. 17, 2011, 2008. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=26047.

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21

Pacheco, Estefan Daniel. "Space, memory, action: insights from behaviour and neurophysiology." Doctoral thesis, Universitat Pompeu Fabra, 2017. http://hdl.handle.net/10803/458526.

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Human memory is fundamentally linked to experience. Traditionally, however, it has been studied in restricted tasks, under constrained experimental conditions. Understanding memory from a situated, embodied, spatial perspective constitutes not only a major scientific challenge but a primary issue in the design of future educational technologies. Indeed, recent developments in virtual and augmented reality (VR/AR) systems provide novel means to organize the interaction with digital content in fully spatial setups. A deeper insight into the behavioral determinants of memory is thus critical to b
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22

Norton, Jonathan Andrew. "FES-standing and muscle spasms : neurophysiology and biomechanics." Thesis, University College London (University of London), 2003. http://discovery.ucl.ac.uk/1383223/.

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Functional Electrical Stimulation (FES) can be used to assist patients with complete paraplegia arising from a traumatic spinal cord injury to stand. In clinical practice the take-up of this technology is poor. It was hypothesised that one potential reason was that the posture during standing was difficult to predict from non-standing biomechanical measures because of the spinal cord's motor responses to standing. In six patients biomecharrical and electrophysiological recordings were made to test whether motor activity arising as a result of standing affected their standing posture. Recording
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23

Maslovskaya, Sofya. "Inverse Optimal Control : theoretical study." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLY013/document.

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Cette thèse s'insère dans un projet plus vaste, dont le but est de s'attaquer aux fondements mathématiques du problème inverse en contrôle optimal afin de dégager une méthodologie générale utilisable en neurophysiologie. Les deux questions essentielles sont : (a) l'unicité d'un coût pour une synthèse optimale donnée (injectivité); (b) la reconstruction du coût à partir de la synthèse. Pour des classes de coût générales, le problème apparaît très difficile même avec une dynamique triviale. On a donc attaqué l'injectivité pour des classes de problèmes spéciales : avec un coût quadratique, la dyn
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Maslovskaya, Sofya. "Inverse Optimal Control : theoretical study." Electronic Thesis or Diss., Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLY013.

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Cette thèse s'insère dans un projet plus vaste, dont le but est de s'attaquer aux fondements mathématiques du problème inverse en contrôle optimal afin de dégager une méthodologie générale utilisable en neurophysiologie. Les deux questions essentielles sont : (a) l'unicité d'un coût pour une synthèse optimale donnée (injectivité); (b) la reconstruction du coût à partir de la synthèse. Pour des classes de coût générales, le problème apparaît très difficile même avec une dynamique triviale. On a donc attaqué l'injectivité pour des classes de problèmes spéciales : avec un coût quadratique, la dyn
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25

Voirin, James [Verfasser]. "Ecology and Neurophysiology of Sleep in Wild Sloths / James Voirin." Konstanz : Bibliothek der Universität Konstanz, 2013. http://d-nb.info/104290054X/34.

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26

Saftenku, Elena. "Anomalous and apparently anomalous diffusion in the area of neurophysiology." Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-194237.

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27

Saatchi, Mohammad Reza. "Developments in signal processing for computerised diagnosis in clinical neurophysiology." Thesis, Sheffield Hallam University, 1992. http://shura.shu.ac.uk/14384/.

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The aim of this study was to apply signal processing techniques to a potential known as the contingent negative variation (CNV) in order to aid detection of schizophrenia, Parkinson's disease (PO) and Huntington's Disease (lID). A data recording system was constructed and used to obtain data from 20 schizophrenic patients, 16 PO patients, 21 -at-risk- of HD patients, 11 HD patients and 43 normal control subjects. The data included the CNV, electro-oculograms (required for the preprocessing of the CNV) and the subjects reaction times to an acoustic stimulus. The CNV waveforms were initially pre
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28

Mears, Ryan Phillip. "NEUROPHYSIOLOGY OF AUDITORY INHIBITORY GATING IN RAT MEDIAL PREFRONTAL CORTEX." Bowling Green State University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1151343744.

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Hilton, Emma. "Towards an understanding of the neurophysiology of cough in humans." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/towards-an-understanding-of-the-neurophysiology-of-cough-in-humans(f314ffdd-9ea0-4732-af27-afd7f34f9ffa).html.

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Rationale: Chronic cough (cough >8 weeks) is common, leads to an impaired quality of life, and is difficult to treat. Despite intensive investigation, ~40% of patients referred to a specialist cough clinic will remain resistant to treatment targeted at peripheral triggers such as reflux disease, rhino-sinusitis or airways inflammation. An improved understanding of underlying mechanisms in such patients would facilitate drug development. I propose that there are several important similarities between pain and cough that can be exploited better to understand underlying mechanisms. In chronic pai
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30

Weil, Jon C. (Jon Christopher). "Characterizing Spontaneous Neurophysiological Activity with Measures of Statistical Serial Dependence: a Summary Statistic and an Extension of the Joint Interval Histogram." Thesis, University of North Texas, 1994. https://digital.library.unt.edu/ark:/67531/metadc278067/.

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Two measures which indicate statistical serial dependence were evaluated. The n-dimensional Average Stored Information index (ndASI) is a measure of conditional information, which compares the entropies of higher order conditional distributions to estimate average statistical serial dependence. The generalized ranked joint interval histogram (RJIH-o) is a new nonparametric graphical analysis method. It extends the joint interval histogram by depicting longer interval sequences and can be interpereted precisely analagously to the joint interval histogram. The generalized ranked joint interval h
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31

Dukes, David Jefferson. "Brain Topography of Leadership: Neurophysiological Correlates of the Leadership Opinion Questionnaire." Thesis, University of North Texas, 1995. https://digital.library.unt.edu/ark:/67531/metadc332480/.

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Laboratory research was performed to understand leadership by attempting to link EEG baseline frequency patterns with data from the Leadership Opinion Questionnaire (LOQ) assessment survey. Research began with 293 right-handed males, 18 to 26 years-old, who completed the LOQ. Based on their scores, 61 subjects, grouped by the Ohio State Leadership Quadrants, were tested using brain-mapping technology.
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32

Stratford, Kenneth James. "Quantal analysis - theory and practice : a study of chemical synaptic transmission." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333360.

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33

Tolias, Christos. "Extracellular superoxide and nitric oxide : a real-time investigation in the role of free radicals in brain cell physiology and pathophysiology in vitro." Thesis, University of Warwick, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.484267.

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曾昭雪 and Chiu-suet Margaret Tsang. "The regulation of Endothelin-1 during mouse brain development and perinatal cerebral ischemia." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31221749.

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35

McEwan, Carolyn Audrey. "Stimulation of human neuroblastoma cells using a planar microelectrode array." Thesis, University of Glasgow, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343915.

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McDonald, James Scott. "Visual processing of contrast in natural scenes." Thesis, University of Newcastle Upon Tyne, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270824.

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Chen, Ying. "Study of the dorsal root reflex activity in an isolated mammalian spinal cord preparation." Thesis, University of Southampton, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359141.

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Tsang, Chiu-suet Margaret. "The regulation of Endothelin-1 during mouse brain development and perinatal cerebral ischemia /." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B20622399.

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39

Fritz, Thomas. "Emotion investigated with music of variable valence : neurophysiology and cultural influence." Phd thesis, Universität Potsdam, 2008. http://opus.kobv.de/ubp/volltexte/2009/2911/.

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Music is a powerful and reliable means to stimulate the percept of both intense pleasantness and unpleasantness in the perceiver. However, everyone’s social experiences with music suggest that the same music piece may elicit a very different valence percept in different individuals. A comparison of music from different historical periods suggests that enculturation modulates the valence percept of intervals and harmonies, and thus possibly also of relatively basic feature extraction processes. Strikingly, it is still largely unknown how much the valence percept is dependent on physical propert
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40

Yang, In Hong. "The study of the neurophysiology of high strain rate nerve injury." Texas A&M University, 2003. http://hdl.handle.net/1969.1/416.

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The study of the mechanism of traumatic brain injury (TBI) processes at the cellular level is vital to obtain characterization of nerve cell damage after mechanical deformation. This understanding is needed to find feasible therapeutic targets for mechanically damaged neurons. To study the cellular level of TBI damage, development of a new in vitro cellular model of TBI might be done to simulate in vivo cellular TBI. In this research, two studies were performed: (1) the design and construction of an in vitro cell stretching device to mechanically injure cells and (2) the characterization o
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Brown, Katlyn Elizabeth. "The neurophysiology of sensorimotor integration in healthy aging and chronic stroke." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/63184.

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Background: General decline in motor performance is often cited in healthy aging, and motor deficits persist into the chronic phase of stroke recovery. Abnormalities in sensorimotor integration may underlie these motor deficits; however, the effect of aging and chronic stroke on sensorimotor integration neurophysiology is not well understood. Further, investigation into the plasticity of sensorimotor integration is important to establish in populations experiencing sensorimotor decline. Methods: The overall objective of this thesis was to comprehensively understand the neurophysiology of sens
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42

Issa, Fadi Aziz. "Effect of Social Status on the Behavior and Neurophysiology of Crayfish." Digital Archive @ GSU, 2008. http://digitalarchive.gsu.edu/biology_diss/35.

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Adaptation to changing social conditions is important for many social animals. Here, the effects of social experience on the behavior and neurophysiology of the red swamp crayfish, Procambarus clarkii, were studied. Evidence is presented that shows juvenile crayfish interact and form social order, and their behavior patterns shift in accordance to social status. Dominant animals maintain a high level of aggressive behavior, while subordinates shift their behavior pattern from aggressive to submissive behavior. Adult male crayfish show similar behavior pattern during dominance formation. Howeve
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43

McBride, Jennifer Ann. "Repetition or targets and distractors in visual search : Behaviour and neurophysiology." Thesis, University of Bristol, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501505.

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Repetition of target properties across consecutive visual search trials affects response time: a phenomenon known as "repetition priming" in visual search. Ten visual search experiments are reported which were designed to better characterise the mechanism(s) producing this phenomenon. After replication of the effects reported in the literature with a new paradigm (Experiment 1), two further experiments (Experiments 2 and 3) were designed to identify the optimum paradigm with which to study these effects further, and revealed that repetition priming occurs only under particular circumstances. T
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French, Richard L. B. "Exploring links between neurophysiology and behaviour with a behaviour-based robot." Thesis, University of Southampton, 2002. https://eprints.soton.ac.uk/256282/.

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Birge, Charles. "The Addiction of Transparency: Observations on the Emotional Neurophysiology of Whiteness." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1554891264402108.

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46

Tran, Christine. "Développement de sondes activables à deux photons pour une utilisation en neurosciences." Thesis, Sorbonne Paris Cité, 2015. http://www.theses.fr/2015USPCB165.

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Des sondes photoactivables (composés “cagés”) dérivées de la 2-hydroxyméthylène-diméthylaminoquinoléine, ont été préparées et testées pour une application en neurophysiologie. Ces sondes montrent une stabilité hydrolytique élevée et une faible fluorescence, avec des cinétiques de photofragmentation rapides sous irradiation UV (365 nm). Il en est également de même dans des conditions biphotoniques en IR proche (730 nm). Une optimisation de cette plateforme a été réalisée en modifiant la nature et la position des substituants du chromophore, en augmentant la conjugaison et en incorporant des élé
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47

Tucker, Gayle. "Mathematical modelling in neurophysiology : neuronal geometry in the construction of neuronal models." Thesis, University of Oxford, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414405.

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48

Kelly, Rachel Louise. "Understanding the neurophysiology of action interpretation in right and left-handed individuals." Diss., Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/53589.

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Investigating the neurophysiology behind our action encoding system offers a way of probing the underlying mechanisms regarding how we understand seen action. The ability to mentally simulate action (motor simulation) is a strong proposal to understand how we interpret others’ actions. The process of how we generate accurate motor simulations is proposed to be reliant on the context of the movement and sensory feedback from the limb. However, the neurophysiological mechanisms behind motor simulation are not yet understood. Known motor physiology for right-handed individuals show there is a lef
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49

Szcz??sniak, Michal Marcin Clinical School St George Hospital Faculty of Medicine UNSW. "Experimental and pathophysiological modulation of oesophageal afferent pathways: implications for oesophago-pharyngeal reflexes, regurgitation and symptom perception /." Awarded by:University of New South Wales. Clinical School - St George Hospital, 2008. http://handle.unsw.edu.au/1959.4/41094.

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The work presented in this thesis concerns neurophysiology and pharmacology of the oesophageal afferent pathways involved in oesophago-pharyngeal reflexes and oesophageal nociception. Disturbances of reflexes governing contractile and relaxation responses of the upper oesophageal sphincter (DOS) are likely to be implicated in the pathophysiology of conditions involving excessive oesophago-pharyngeal regurgitation, impaired oesophageal clearance, and an abnormal belch reflex. Visceral hypersensitivity, a heightened perception of gastrointestinal sensation is frequently observed in functional ga
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Xu, Bin. "Axonal growth, neuronal damage and epileptogenesis /." *McMaster only, 2002.

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