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Artykuły w czasopismach na temat „New Century Club (Philadelphia, Pa.)”

Autor: Grafiati

Data publikacji: 29 lipca 2024

Data aktualizacji: 28 lipca 2025

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Gerlach, Larry. "The Camden Merritt, New Jersey’s Premier Nineteenth-Century Baseball Team." New Jersey Studies: An Interdisciplinary Journal 9, no. 2 (2023): 35–57. http://dx.doi.org/10.14713/njs.v9i2.326.

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With the emergence of baseball as America’s national sporting pastime, Camden civic and business leaders decided in 1881 to organize a professional team. This article examines the brief but spectacular history of the Albert Merritt Base Ball Club, one of the best minor league teams of the nineteenth century. Examined are the social and economic reasons for organizing a professional team, the unique founding of the club, the construction of a playing facility, and team finances including player salaries. The 1883 Merritt, which advanced every player to the major leagues, was a juggernaut, domin

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Wells, Julie, Richard Maser, Ashley Tucker, et al. "Abstract 927: Developing new mouse models of metastatic lung cancer." Cancer Research 82, no. 12_Supplement (2022): 927. http://dx.doi.org/10.1158/1538-7445.am2022-927.

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Abstract INTRODUCTION: The focus of this work is to develop new mouse models for metastatic lung cancer. Lung cancer is the leading cause of cancer deaths worldwide and greater than 75% of human lung cancer deaths can be attributed to metastasis. Metastatic disease in most existing mouse models of pulmonary adenocarcinoma is typically sporadic and often requires aging mice for several months. These factors limit the usefulness of mouse models for basic and pre-clinical research aimed at identifying effective treatments of metastatic disease. METHODS AND RESULTS: We have developed new mouse mod

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Ramkissoon, Paige, Julie Wells, Richard S. Maser, et al. "Abstract 1321: New mouse models of metastatic lung cancer." Cancer Research 83, no. 7_Supplement (2023): 1321. http://dx.doi.org/10.1158/1538-7445.am2023-1321.

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Abstract INTRODUCTION: Lung cancer is the leading cause of cancer deaths worldwide and greater than 75% of human lung cancer deaths can be attributed to metastasis. Metastatic disease in most existing mouse models of pulmonary adenocarcinoma is typically sporadic and often requires aging mice for several months. These factors limit the usefulness of most current mouse models for basic and pre-clinical research aimed at identifying mechanisms and effective treatments of metastatic disease. We have developed two novel mouse models of metastatic lung cancer and report here on changes in protein e

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Lugassy, Claire, and Raymond L. Barnhill. "Abstract IA06: Concepts of cancer and metastasis: Historical perspective." Cancer Research 80, no. 19_Supplement (2020): IA06. http://dx.doi.org/10.1158/1538-7445.mel2019-ia06.

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Abstract In medicine, as in all of human history, there is a permanent back and forth between two principal modes of thought: (i) magical/religious/ fears/obscurantism, leading to dogma;, and (ii) intellectual activities resulting in the questioning of dogma and opening doors to new concepts. Concerning cancer, since ancient Egypt, several methods of thinking have been instituted and then rejected, influenced by new discoveries but also by the cultural context. With respect to mechanisms of cancer metastasis, after considerable debate in the 19th century, intravascular dissemination of cancer

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Fisher, Julie A. "Dreams and the Invisible World in Colonial New England: Indians, Colonists, and the Seventeenth Century. By Ann Marie Plane. (Philadelphia, PA: University of Pennsylvania Press, 2014. Pp. xi, 237. $59.95.)." Historian 78, no. 4 (2016): 771–73. http://dx.doi.org/10.1111/hisn.12366.

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Melo, Abner Antonio Murray, Jesus Antonio Ocejo Gallegos, and Jaime Rafael Merchan. "Abstract C121: Epidemiological characteristics and patterns of recurrence of renal cell carcinoma in Hispanics: A single US center cohort study." Cancer Epidemiology, Biomarkers & Prevention 32, no. 1_Supplement (2023): C121. http://dx.doi.org/10.1158/1538-7755.disp22-c121.

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Abstract Renal cell carcinoma (RCC) is amongst the ten most prevalent malignancies in the United States, with 76,000 new cases each year and almost 14,000 deaths. Over the past half-century, RCC has more than doubled in incidence. RCC seems to have a greater incidence among Hispanics with a nearly three-fold increase. The epidemiology of RCC has been studied. However, there is a gap in knowledge on disparities in RCC within minority populations. We aimed to analyze epidemiologic patterns of RCC within our community, where Hispanics alone make up 70% of the population. We conducted a retrospect

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Barker, Anthony J. "Roxann Wheeler. The Complexion of Race: Categories of Difference in Eighteenth-Century British Culture. (New Cultural Studies.) Philadelphia, Pa.: University of Pennsylvania Press. 2000. Pp. ix, 371. $26.50. ISBN 0-8122-1722-5." Albion 33, no. 3 (2001): 473–74. http://dx.doi.org/10.2307/4053230.

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Dolgos, Robin, Romuald Parmentier, Jing Wang, et al. "Abstract 5205: ECM-free patient-derived organoids preserve diverse prostate cancer lineages and uncover in vitro-enriched cell types." Cancer Research 85, no. 8_Supplement_1 (2025): 5205. https://doi.org/10.1158/1538-7445.am2025-5205.

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Background: Patient-derived organoids (PDOs) offer new opportunities to model various cancers. However, their application in prostate cancer (PCa) has been hampered by poor success rates and overgrowth of cell types which are not representative of the patient samples. Here, we aimed at modulating culture conditions and investigating in vitro-associated cellular heterogeneity to identify refined PCa PDO culture conditions. Methods: A cohort of 164 diverse samples was obtained from 162 PCa patients undergoing radical prostatectomy, prostatic biopsies, transurethral resection of the prostate or t

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Mitchell-Hutchinson, Naomi, Paige Ramkissoon, Julie Wells, et al. "Abstract 5182: Transcriptomic analysis of mouse models of lung adenocarcinoma with different metastatic phenotypes." Cancer Research 85, no. 8_Supplement_1 (2025): 5182. https://doi.org/10.1158/1538-7445.am2025-5182.

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Introduction: Lung cancer is the leading cause of cancer deaths worldwide with most deaths attributed to metastatic disease. Existing mouse models of lung adenocarcinoma (LUAD) rarely become metastatic, limiting their usefulness for basic and pre-clinical research aimed at identifying mechanisms of metastatic disease. We have developed two novel mouse models of LUAD, KPDT-1 and KPDT-2, that feature cell type-specific inducible oncogenic KrasG12D, loss of Trp53 function, and deleted/truncated Dicer1. The survival times, rate of tumor progression, and metastatic phenotypes of these models depend

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KITLV, Redactie. "Book Reviews." New West Indian Guide / Nieuwe West-Indische Gids 77, no. 1-2 (2003): 127–96. http://dx.doi.org/10.1163/13822373-90002533.

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-Philip D. Morgan, Marcus Wood, Blind memory: Visual representations of slavery in England and America 1780-1865. New York: Routledge, 2000. xxi + 341 pp.-Rosemarijn Hoefte, Ron Ramdin, Arising from bondage: A history of the Indo-Caribbean people. New York: New York University Press, 2000. x + 387 pp.-Flávio dos Santos Gomes, David Eltis, The rise of African slavery in the Americas. Cambridge: Cambridge University Press, 2000. xvii + 353 pp.-Peter Redfield, D. Graham Burnett, Masters of all they surveyed: Exploration, geography, and a British El Dorado. Chicago: University of Chicago Press, 20

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Ananthula, Aneesha, Katharine Thomas, Lily Chen, et al. "Abstract P4-07-21: Neo-adjuvant chemotherapy in various breast cancer subtypes in the 21st century." Cancer Research 83, no. 5_Supplement (2023): P4–07–21—P4–07–21. http://dx.doi.org/10.1158/1538-7445.sabcs22-p4-07-21.

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Abstract Introduction Breast cancer is a complex, heterogeneous disease encompassing a spectrum of subtypes with distinct biological features, each having unique responses to various treatment modalities and different clinical outcomes. The type of neoadjuvant chemotherapy (NAC) for locally advanced breast cancer is decided based on breast cancer subtype, which includes triple negative breast cancer (TNBC), hormone receptor positive breast cancer (HR+BC), HER2+ breast cancer (HER2+BC) and triple positive breast cancer (TPBC). Multiple NAC regimens exist but have not been directly compared to d

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Kim, Min-Hyeok. "Revisiting the contested history of democracy in the age of populism - Jan-Werner Müller, Contesting Democracy: Political Ideas in Twentieth Century Europe New Haven, CT, Yale University Press, 2011. - Jan-Werner Müller, What is Populism? Philadelphia, PA, University of Pennsylvania Press, 2016." Japanese Journal of Political Science 21, no. 1 (2019): 43–46. http://dx.doi.org/10.1017/s1468109919000185.

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Zubair, Asif, Rich Chapple, Sivaraman Natarajan, et al. "Abstract 456: Jointly leveraging spatial transcriptomics and deep learning models for image annotation achieves better-than-pathologist performance in cell type identification in tumors." Cancer Research 82, no. 12_Supplement (2022): 456. http://dx.doi.org/10.1158/1538-7445.am2022-456.

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Abstract For over 100 years, the traditional tools of pathology, such as tissue-marking dyes (e.g. the H&E stain) have been used to study the disorganization and dysfunction of cells within tissues. This has represented a principal diagnostic and prognostic tool in cancer. However, in the last 5 years, new technologies have promised to revolutionize histopathology, with Spatial Transcriptomics technologies allowing us to measure gene expression directly in pathology-stained tissue sections. In parallel with these developments, Artificial Intelligence (AI) applied to histopathology tissue i

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Gondal, Mahnoor, Yi Bao, Rahul Mannan, Jing Hu, Arul Chinnaiyan, and Marcin Cieslik. "Abstract A094: Single-cell Transcriptomics Unveils Novel Regulators of MHC Expression: Implications for Cancer Immunotherapy." Cancer Immunology Research 13, no. 2_Supplement (2025): A094. https://doi.org/10.1158/2326-6074.io2025-a094.

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Abstract Background: Major histocompatibility complex (MHC) genes are critical for the adaptive immune system, enabling T-cells to detect and eliminate cancer cells. Many cancers evade immune surveillance by altering MHC expression, leading to resistance to immune checkpoint blockade (ICB) therapy. Understanding MHC regulation in normal and cancerous states is essential for developing effective immunotherapies. Previous studies using bulk RNA-sequencing failed to measure cancer cell-specific MHC expression accurately. This study aims to decode MHC transcriptional regulation in healthy tissues

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Formenti, Silvia C. "Abstract SY43-02: Adapting clinical radiation therapy to immune checkpoint blockade." Cancer Research 82, no. 12_Supplement (2022): SY43–02—SY43–02. http://dx.doi.org/10.1158/1538-7445.am2022-sy43-02.

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Abstract Focal radiation therapy has demonstrated to elicit inflammatory and immune responses that contribute to cancer immunosurveillance, but may also have unwanted systemic effects. The application of ionizing radiation to cancer, which is the basis for the field of radiation oncology, has evolved to define and exploit the therapeutic window between radiation cytocidal effects in tumors versus those in normal tissue. The original standardization of specific dose-fractionation regimens reflected the results of decades of empirical experience to find the best balance between local control of

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Vontz, Gabrielle, Jun Li, Ruixia Ma, et al. "Abstract 1659: Development of HJC0152, its analogs and protein degraders to modulate STAT3 for triple-negative breast cancer therapy." Cancer Research 83, no. 7_Supplement (2023): 1659. http://dx.doi.org/10.1158/1538-7445.am2023-1659.

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Abstract Breast cancer represents the most commonly diagnosed female malignancy worldwide. Although breast cancer screening and treatments have improved significantly over the last half-century, aggressive subtypes like triple-negative breast cancer (TNBC) as well as growing chemoresistance cases continue to evade frontline therapies. STAT3, a transcription factor involved in cell proliferation, survival, and malignant transformation, plays a key role in mammary carcinogenesis, resistance, and recurrence. Both STAT3 overexpression and aberrant activation are frequently observed in primary brea

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Cho, Hanbyul, Noshad Hosseini, Yi Hsiao, et al. "Abstract 5013: The interplay of genomic aberrations, transcriptional states, and therapeutic responses in lung cancer." Cancer Research 85, no. 8_Supplement_1 (2025): 5013. https://doi.org/10.1158/1538-7445.am2025-5013.

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Lung cancer leads cancer-related deaths worldwide, with 2024 estimates of 234,580 new cases in the United States. This study explores the roles of tumor driver aberrations, epithelial transcriptional states, and microenvironment composition in lung cancer outcomes using proteogenomic data from 965 patients across the Clinical Proteomic Tumor Analysis Consortium (CPTAC) and International Cancer Proteogenome Consortium (ICPC). We examined oncogenic alterations, epithelial and stromal cell type enrichment distributions, transcriptional modules activities, and drug sensitivities in lung adenocarci

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Murray, Abner A., Jesus A. Ocejo Gallegos, Sandra Jones, et al. "Abstract 722: Epidemiological characterization of renal cell carcinoma in Hispanics: A single US center cohort study." Cancer Research 83, no. 7_Supplement (2023): 722. http://dx.doi.org/10.1158/1538-7445.am2023-722.

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Abstract Background: Annually, there are over 400,000 new cases of renal cell carcinoma (RCC) and more than 170,000 deaths worldwide. RCC is one of the top ten more prevalent malignancies in the United States, with 76,000 new cases each year and almost 14,000 deaths. Over the past half-century, RCC has more than doubled in incidence. RCC seems to have a greater incidence among Hispanics with a nearly three-fold increase. The epidemiology of RCC in the Caucasian population has been previously studied. However, there is a knowledge gap on disparities in RCC on minority populations. Studying the

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KITLV, Redactie. "Book Reviews." New West Indian Guide / Nieuwe West-Indische Gids 75, no. 3-4 (2001): 297–357. http://dx.doi.org/10.1163/13822373-90002555.

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-Stanley L. Engerman, Heather Cateau ,Capitalism and slavery fifty years later: Eric Eustace Williams - A reassessment of the man and his work. New York: Peter Lang, 2000. xvii + 247 pp., S.H.H. Carrington (eds)-Philip D. Morgan, B.W. Higman, Writing West Indian histories. London: Macmillan Caribbean, 1999. xiv + 289 pp.-Daniel Vickers, Alison Games, Migration and the origins of the English Atlantic world. Cambridge MA: Harvard University Press, 1999. xiii + 322 pp.-Christopher L. Brown, Andrew Jackson O'Shaughnessy, An empire divided: The American revolution and the British Caribbean. Philade

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Paidi, Santosh K., Joel R. Troncoso, Narasimhan Rajaram, and Ishan Barman. "Abstract 1943: Elucidating early tumor microenvironmental changes due to immunotherapy with label-free Raman spectroscopy and machine learning." Cancer Research 82, no. 12_Supplement (2022): 1943. http://dx.doi.org/10.1158/1538-7445.am2022-1943.

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Abstract Clinical benefit is observed in only a limited fraction of patients that undergo immunotherapy for a variety of cancer types. Therefore, the determination of robust biomarkers for accurate prediction of response to immunotherapeutic agents remains one of the grand challenges of 21st century. Our primary goal was to investigate if phenotypic differences due to treatment with ICI can be recognized with minimally perturbative molecular tools and guide personalization of immunotherapy. In this work, we provide first-in-class evidence that Raman spectroscopy (an optical method) and machine

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Holder, Sheldon L., Robert A. Winn, and Wafik S. El-Deiry. "Abstract 1002: The historically black colleges and universities cancer trial consortium: A way forward to diversifying cancer clinical trials." Cancer Research 84, no. 6_Supplement (2024): 1002. http://dx.doi.org/10.1158/1538-7445.am2024-1002.

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Abstract The National Comprehensive Cancer Center Network cancer guidelines state that the best management for a cancer patient is on a clinical trial. However, the demographics of 74 registration trials for oral cancer therapies from 2009 - 2019 show only 2.5% of participating patients were Black. Similarly, of the 3,593 patients enrolled in all registration trials for new cancer drugs approved by the FDA in 2019, only 4% were Black patients. A third analysis showed that between 2008 and 2018, only 3.1% of cancer trial patients were Black. The underrepresentation of Black patients in cancer c

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Shaiken, Tattym E. "Abstract A040: Suppressing the cytomatrix elastic solid phase of cytoplasm will eliminate the root cause of cancer." Cancer Research 84, no. 3_Supplement_2 (2024): A040. http://dx.doi.org/10.1158/1538-7445.canevol23-a040.

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Abstract The Warburg effect, the increase of glucose uptake rate and lactate production, is a tremendous metabolic switch, a prominent cancer hallmark, and a century-old mystery. We recently solved an age-old problem of biochemistry, how myriad diverse chemical reactions coincide in the cell, by chemically separating elastic solid (cytomatrix) and viscous fluid (cytosol) phases of cytoplasm (iScience, 2023, PMID:36824274) that can elucidate a role of the Warburg effect in tumors. Biochemical reactions within the cytoplasm are catalytic and performed by enzyme complexes. Catalytic complexes are

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Smith, Robert, Renáta Bozó, Peter B. Dean, et al. "Abstract P5-02-19: Why Are We Failing to Cure So Many Cases of Lobular Breast Cancer?" Clinical Cancer Research 31, no. 12_Supplement (2025): P5–02–19—P5–02–19. https://doi.org/10.1158/1557-3265.sabcs24-p5-02-19.

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Abstract Invasive lobular cancer of the breast (ILC) is responsible for more than its share of treatment failures. Long-term survival of women with classic ILC has not improved significantly over the past half century, despite major improvements in breast cancer therapy and diagnosis. Foote and Stewart considered lobular carcinoma in situ (LCIS) to be the precursor of ILC, and that the “the mass eruption of tumor cells” occurred through “some lytic action of the tumor cells, naturally not to be detected by anatomic study.” Ackerman and Del Regato accepted this proposed mechanism, concluding th

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Royce, Melanie E., Jennifer J. Lee, Christy L. Osgood, et al. "Abstract P5-19-02: Methodological approaches to the use of real-world data(RWD) for medical products to treat breast cancer: An FDA oncology center of excellence evaluation of RWD submissions." Cancer Research 82, no. 4_Supplement (2022): P5–19–02—P5–19–02. http://dx.doi.org/10.1158/1538-7445.sabcs21-p5-19-02.

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Abstract Background: Aligning with 21st Century Cures legislation, FDA is exploring various methodologies to advance appropriate uses of Real-World Data (RWD) to generate Real-World Evidence (RWE). Inclusion of RWD to support regulatory decision making has increased in oncology, and this review specifically focused on characterizing RWD submissions for the treatment of breast cancer (BC). Methods: A systematic search was conducted using internal FDA databases to identify RWD submissions from 2010 to 2020. Search terms included real world evidence, real world data, cancer registry, administrati

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Kolomiyets, Lada. "The Psycholinguistic Factors of Indirect Translation in Ukrainian Literary and Religious Contexts." East European Journal of Psycholinguistics 6, no. 2 (2019): 32–49. http://dx.doi.org/10.29038/eejpl.2019.6.2.kol.

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The study of indirect translations (IT) into Ukrainian, viewed from a psycholinguistic perspective, will contribute to a better understanding of Soviet national policies and the post-Soviet linguistic and cultural condition. The paper pioneers a discussion of the strategies and types of IT via Russian in the domains of literature and religion. In many cases the corresponding Russian translation, which serves as a source text for the Ukrainian one, cannot be established with confidence, and the “sticking-out ears” of Russian mediation may only be monitored at the level of sentence structure, wh

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Abubakar, Mustapha, Shaoqi Fan, Maire A. Duggan, et al. "Abstract SY25-02: Double-edged “soil”: Stromal microenvironment in breast cancer development." Cancer Research 82, no. 12_Supplement (2022): SY25–02—SY25–02. http://dx.doi.org/10.1158/1538-7445.am2022-sy25-02.

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Abstract Double-edged “Soil”: Stromal Microenvironment in Breast Cancer Development Mustapha Abubakar, MD, PhD1; Shaoqi Fan, MPH1; Máire A. Duggan, MD, FRCPC2; Ruth M. Pfeiffer, PhD1; Scott Lawrence, M.S.3; Kathryn Richert-Boe, MD4; Andrew G. Glass, MD4; Teresa M. Kimes, MS4; Jonine D. Figueroa, PhD, MPH5; Thomas E. Rohan, MBBS, PhD6; Gretchen L. Gierach, PhD, MPH1. Affiliations 1Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institute of Health (NIH), USA2Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, T2N2Y9, Alberta, Canada

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"Book Reviews." City & Community 4, no. 2 (2005): 217–25. http://dx.doi.org/10.1111/j.1540-6040.2005.00112.x.

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Manufacturing Suburbs , by Robert Lewis ( ed. ). Philadelphia : Temple University Press , 2004 . 304 pp . ISBN 1‐59213‐085‐2 ( cloth ) $68.50. ISBN 1‐59213‐086‐0 ( paper ) $24.95. Hollow City: The Siege of San Francisco and the Crisis of American Urbanism , by Rebecca Solnit and Susan Schwartzenberg . New York , NY : Verso , 2002 . 182 pp . ISBN 1‐85984‐363‐8 ( cloth ) $20.00 . Popular Culture in the Age of White Flight: Fear and Fantasy in Suburban Los Angeles , by Eric Avila . Berkeley : University of California Press , 2004 . Volume 13 in the American Crossroads Series , edited by Earl Lewi

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Allen, Rob. "Lost and Now Found: The Search for the Hidden and Forgotten." M/C Journal 20, no. 5 (2017). http://dx.doi.org/10.5204/mcj.1290.

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The Digital TurnMuch of the 19th century disappeared from public view during the 20th century. Historians recovered what they could from archives and libraries, with the easy pickings-the famous and the fortunate-coming first. Latterly, social and political historians of different hues determinedly sought out the more hidden, forgotten, and marginalised. However, there were always limitations to resources-time, money, location, as well as purpose, opportunity, and permission. 'History' was principally a professionalised and privileged activity dominated by academics who had preferential access

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Rose, Megan Catherine, Haruka Kurebayashi, and Rei Saionji. "Kawaii Affective Assemblages." M/C Journal 25, no. 4 (2022). http://dx.doi.org/10.5204/mcj.2926.

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Introduction The sensational appearance of kawaii fashion in Tokyo’s Harajuku neighborhood—full of freedom, fun, and frills— has captivated hearts and imaginations worldwide. A key motivational concept for this group is “kawaii” which is commonly translated as “cute” and can also be used to describe things that are “beautiful”, “funny”, “pretty”, “wonderful”, “great”, “interesting”, and “kind” (Yamane 228; Yomota 73; Dale 320). Representations in media such as the styling of Harajuku street model and J-pop star Kyary Pamyu Pamyu, directed by Sebastian Masuda, have helped bring this fashion to

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Brien, Donna Lee. "Bringing a Taste of Abroad to Australian Readers: Australian Wines & Food Quarterly 1956–1960." M/C Journal 19, no. 5 (2016). http://dx.doi.org/10.5204/mcj.1145.

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IntroductionFood Studies is a relatively recent area of research enquiry in Australia and Magazine Studies is even newer (Le Masurier and Johinke), with the consequence that Australian culinary magazines are only just beginning to be investigated. Moreover, although many major libraries have not thought such popular magazines worthy of sustained collection (Fox and Sornil), considering these publications is important. As de Certeau argues, it can be of considerable consequence to identify and analyse everyday practices (such as producing and reading popular magazines) that seem so minor and in

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Sears, Cornelia, and Jessica Johnston. "Wasted Whiteness: The Racial Politics of the Stoner Film." M/C Journal 13, no. 4 (2010). http://dx.doi.org/10.5204/mcj.267.

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We take as our subject what many would deem a waste of good celluloid: the degraded cultural form of the stoner film. Stoner films plot the experiences of the wasted (those intoxicated on marijuana) as they exhibit wastefulness—excessiveness, improvidence, decay—on a number of fronts. Stoners waste time in constantly hunting for pot and in failing to pursue more productive activity whilst wasted. Stoners waste their minds, both literally, if we believe contested studies that indicate marijuana smoking kills brains cells, and figuratively, in rendering themselves cognitively impaired. Stoners w

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