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Rozprawy doktorskie na temat „Novel Formulations”

Autor: Grafiati

Data publikacji: 2 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Lilley, Kevin James. "Novel cement formulations for orthopaedic applications." Thesis, University of Birmingham, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.442648.

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Angkawinitwong, Ukrit. "Novel biopharmaceutical formulations from electrohydrodynamic atomisation." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10042642/.

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Biopharmaceutical forms a new class of medicine which is biologically active and produced by recombinant technology or obtained from living organisms. It can be diversified into a range of subtype of drugs such as therapeutic enzymes, monoclonal antibodies, subunit proteins, nucleic acid and genetic materials. They have been used extensively for clinical application involving disease treatments, prevention and diagnosis. Unlike small molecule compounds, their chemical structures are more complex and can crucially influence their activity. However, these highly ordered conformation are often tr

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Guzmán, Medrano Manuel. "Novel vulcanising ingredients: towards greener rubber formulations." Doctoral thesis, Universitat Ramon Llull, 2012. http://hdl.handle.net/10803/83592.

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L'òxid de zinc és un compost àmpliament utilitzat en la indústria del cautxú a causa de les excel•lents propietats que mostra com activador per a la vulcanització amb sofre. Malgrat les seves característiques superiors, hi ha una creixent preocupació sobre els seus efectes mediambientals i nombrosos estudis s’han portat a terme per tal de reduir els nivells de ZnO als compostos de cautxú o per a substituir-lo. Entre totes les alternatives propostes per reduir la quantitat d'òxid de zinc, l'ús de nanopartícules de ZnO amb una alta superfície específica sembla prometedor. Una altra proposta per

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4

Luo, E.-Ching. "Topical therapy with novel targeted releasing formulations." Thesis, De Montfort University, 2015. http://hdl.handle.net/2086/11436.

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Aims Novel low toxicity formulations using biomaterial (i.e. gelatin) for triggered release and controlled manner of formulated therapeutic agent for treatment of immuno-inflammatory disease on the skin were studied in the PhD project. It is a challenging concept because of difficulties in targeting and controlling for the releases that is tailored to disease severity or lesional inflammation extent. Background Psoriasis is a complicated disease with multi-factorial pathogenesis. Potent anti-psoriatic drugs are available but for managing the symptoms of the disease. Due to the toxicity of the

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LI, KUN. "Development of novel formulations based on biopolymers." Doctoral thesis, Università degli studi di Genova, 2021. http://hdl.handle.net/11567/1046199.

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Biopolymers, generally prepared from renewable sources, have attracted increasing attention due to their unique properties, such as nontoxicity, biodegradability and biocompatibility. Indeed, the above materials have been widely applied in the biomedical field, in the development of electronic devices as well as in the food packaging. Two of the most extensively studied and exploited biopolymers are poly(lactic acid) (PLA) and polycaprolactone (PCL), which have been the objects of the present work. Despite the significant interest in these polymers, for large-scale exploitation of both PLA and

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Karolia, Raisa. "Investigating the cleaning efficacy of novel oral care formulations." Thesis, University of Sheffield, 2015. http://etheses.whiterose.ac.uk/12104/.

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Dentinal wear is a complex event system that is dependent on the quality of the dentinal surface and that of the toothbrush and toothpaste used. The wear properties of toothpaste mixtures are commonly characterised by the dentine abrasion it causes. This thesis aims to investigate not only this macroscopic wear but also to further analyse in detail the behaviour of the abrasive particles within toothpaste by analysing the microscopic tribological scratches caused by these abrasive particles to determine the mechanisms of their cleaning behaviour. This project uses quantitative micro-tribologic

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Stuart, Darrin D. "Development and evaluation of novel liposomal formulations of antisense oligodeoxynucleotides." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0017/NQ46926.pdf.

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8

Puri, Sanyogitta. "Novel functionalized polymers for nanoparticle formulations with anti cancer drugs." Thesis, University of Nottingham, 2007. http://eprints.nottingham.ac.uk/10316/.

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The chemistry and structure of Poly (glycerol adipate) facilitate its substitution with various pendant functional groups leading to modifications of the physicochemical properties of the polymer. Modified backbones then can be selected based upon the properties of the compound to be incorporated. Thus, this could be explored as a drug delivery system without many of the limitations of commercially available polymers. The aim of this study was investigate whether various polymers and drugs interact in a specific manner and whether the nature of these interactions influence the physicochemical

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9

McElhatton, A. "Development and evaluation of novel chlorhexidine formulations for oral healthcare." Thesis, Queen's University Belfast, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246430.

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10

Somavarapu, Satyanarayana. "Novel bioadhesive formulations for mucosal and parenteral delivery of vaccines." Thesis, Aston University, 2001. http://publications.aston.ac.uk/12366/.

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In this work we have established the efficient mucosal delivery of vaccines using absorption enhancers and chitosan. In addition, the use of chitosan was shown to enhance the action of other known adjuvants, such as CTB or Quil-A. Collectively, the results presented herein indicate that chitosan has excellent potential as a mucosal adjuvant. We have evaluated a number of absorption enhancers for their adjuvant activity in vivo. Polyornithine was shown to engender high scrum immune reasons to nasally delivered antigens, with higher molecular weight polyornithine facilitating the best results. W

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11

Primo, Ana Rosa Mendes. "Novel boundary integral formulations for slow viscous flow with moving boundaries." Thesis, Brunel University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242986.

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12

Snelling, Jonathon R. "Characterisation of pharmaceutical and polymer formulations by novel mass spectrometry approaches." Thesis, University of Warwick, 2012. http://wrap.warwick.ac.uk/55294/.

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Since its inception at the beginning of the twentieth century, the field of mass spectrometry has progressed from the realm of physics to an analytical tool that can be found in many fields of science. This is in large part due to continued development and innovation in instrument design. This thesis explores two significant areas of development in mass spectrometry in the last ten years. The first is the development of ambient ionisation techniques. These techniques require little or no sample preparation, and as a result can provide a rapid means of direct analysis. The second development is

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13

Ayensu, Isaac. "Development of novel formulations for mucosal delivery of protein based drugs." Thesis, University of Greenwich, 2012. http://gala.gre.ac.uk/9807/.

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Stable mucoadhesive lyophilised chitosan and thiolated chitosan xerogels have been developed for potential delivery of proteins via the buccal mucosa. Membrane dialysis to eliminate sodium acetate (NaAc) and annealing during lyophilisation cycle (developed by differential scanning calorimetry; DSC) were critical for obtaining optimised porous xerogels. Based on characteristic performance and structural integrity, xerogels containing 10 % (per polymer weight) each of plasticizer (glycerol) and cryoprotectant (D-mannitol) were loaded with bovine serum albumin (BSA) and insulin (INS) as model dru

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14

Kulkarni, Chaitrali S. "Novel formulations of a poorly soluble drug using the extrusion process." Thesis, University of Bradford, 2013. http://hdl.handle.net/10454/7334.

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Hot melt extrusion has attracted recent interest from the pharmaceutical industry and academia as an innovative drug delivery technology. This novel technique has been shown to be a viable and robust method for preparing different drug delivery systems including pellets, implants, tablets, capsules and granules. The aim of this research was to understand hot melt extrusion processing and explore its pharmaceutical applications. Two applications of hot melt extrusion (HME) have been investigated to improve the properties of poorly soluble thermolabile drugs; polymeric solid dispersions and soli

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15

El-Sabawi, Dina. "Novel surface engineering of carrier particles for dry powder inhalation formulations." Thesis, University of Bath, 2005. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.418593.

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16

Schultes, Stephan Johannes Baptist. "Nanoparticles for RNA interference : novel preclinical formulations for siRNA mediated gene therapy." München Verl. Dr. Hut, 2010. http://edoc.ub.uni-muenchen.de/11329/.

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17

Härtl, Elisabeth. "Novel approaches for stabilization and characterization of therapeutic proteins in liquid formulations." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-161927.

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18

Luangwitchajaroen, Yuvared. "Preparation of nanosusponanoemulsion and nanosuspomicroemulsion : novel combination formulations suitable for personalised medicine." Thesis, King's College London (University of London), 2017. https://kclpure.kcl.ac.uk/portal/en/theses/preparation-of-nanosusponanoemulsion-and-nanosuspomicroemulsion(e2a714c8-bcdf-4609-a525-c991b380c779).html.

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A wide variety of formulations have been explored in attempt to improve the apparent aqueous solubility of poorly-water soluble drugs such as oil-in-water nanoemulsions (NE), oil-in-water microemulsions (ME) and drug nanoparticles (NPs). There would be advantage gained if two poorly-water soluble drugs could be combined in a single formulation, particularly with respect to the ability to personalise a patient’s medicine. In this study therefore, two novel combination formulations, which we have termed a “nanosusponanoemulsion (NSNE)” and a “nanosuspomicroemulsion (NSME)”, consisting of either

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19

Yee, Yan Jing. "Evaluation of Novel Resveratrol Conjugate and Nanoparticle Formulations for Enhanced Anticancer Activity." Thesis, Curtin University, 2018. http://hdl.handle.net/20.500.11937/73581.

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Resveratrol is known to undergo rapid metabolism and degradation in vivo. The aim of this project is to synthesise polymeric resveratrol conjugates for formulation into nanoparticles for enhanced anticancer treatment by decreasing the metabolism and degradation rate of resveratrol in vivo. Conjugated resveratrol nanoparticles were found to suppress tumour growth in vivo in a melanoma mouse model although in vitro data shows lesser anti-proliferative effect than resveratrol alone.

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Kassam, Zara. "Degradation of polypropylene and novel blend formulations, and the release of hazardous chemicals." Thesis, Kingston University, 2017. http://eprints.kingston.ac.uk/39247/.

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Jones, Tanya. "Development of a Novel Implant for Drug Delivery." Thesis, Griffith University, 2011. http://hdl.handle.net/10072/367574.

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Background and aim: In situ gelling formulations are liquids that undergo a phase transition to form semi-solid gel structures within the physiological environment. Sustained release of drug products can therefore be delivered via injectable in situ gelling formulations where the gel formed in vivo acts as a drug reservoir, releasing drug via diffusion and/or degradation of the gel. Due to limitations of previously described in situ gelling formulations, the current research project aimed to address these issues and develop a biocompatible injectable in situ gelling formulation/s containing a

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22

Lababidi, Nashrawan [Verfasser], and Marc [Akademischer Betreuer] Schneider. "Preparation of novel multifunctional formulations intended for pulmonary delivery / Nashrawan Lababidi ; Betreuer: Marc Schneider." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2019. http://d-nb.info/1192755081/34.

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Wu, Xiao. "Characterization and evaluation of novel nano/meso-particulate formulations for application to the skin." Thesis, University of Bath, 2008. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501631.

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The use of nano/meso-particles (NP/MP) as constituent of topical formulations of drug and cosmetics has been a topic of considerable interest for the past 20 years. However, the transport mechanism of nanoparticle-associated drug/active following topical application on the skin is still unclear. No general answers have been obtained to such questions as the depth of intact NP penetration into the skin, the skin distribution of active substances, and the fate of the vehicles on/in the skin. The main objective of this thesis, therefore, was to observe the in vitro penetration of fluorescently-la

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Lababidi, Nashrawan Verfasser], and Marc [Akademischer Betreuer] [Schneider. "Preparation of novel multifunctional formulations intended for pulmonary delivery / Nashrawan Lababidi ; Betreuer: Marc Schneider." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2019. http://nbn-resolving.de/urn:nbn:de:bsz:291--ds-284192.

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Campbell, Andrew Lee. "Fabrication of novel functional anisotropic micro-particles for foam stabilisation and structuring in food formulations." Thesis, University of Hull, 2009. http://hydra.hull.ac.uk/resources/hull:2488.

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This thesis is concerned with the fabrication of novel food-grade anisotropic solid particles for foam stabilisation and applications in food formulations. Two main techniques were employed for the fabrication of these particles. Acidic hydrolysis of Nata de Coco bacterial cellulose was used to form cellulose nano-rods which were applied as a foam scaffolding material. Characterisation and modification of Nata de Coco nano-rods was also carried out. It was found that cellulose nano-rods modified with a surface layer of ethyl cellulose exhibited good foamability.Secondly, a combination of in-sh

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26

Cardy, Nicola Dee. "Transport of novel foot care formulations across nail and skin mimetics measured using FTIR-ATR." Thesis, University of Manchester, 2007. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.676724.

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Härtl, Elisabeth [Verfasser], and Gerhard [Akademischer Betreuer] Winter. "Novel approaches for stabilization and characterization of therapeutic proteins in liquid formulations / Elisabeth Härtl. Betreuer: Gerhard Winter." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2013. http://d-nb.info/1043906487/34.

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Stelzner, Johannes Jörg [Verfasser]. "Development and characterisation of novel squalene based adjuvant formulations for yeast vaccines against IBDV / Johannes Jörg Stelzner." Halle, 2018. http://d-nb.info/1153007878/34.

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FALLACARA, Arianna. "Preparation and in vitro characterization of novel pharmaceutical and cosmetic formulations consisting of urea-crosslinked hyaluronic acid." Doctoral thesis, Università degli studi di Ferrara, 2019. http://hdl.handle.net/11392/2487937.

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Hyaluronic acid (HA) is widely used in pharmaceutics, medicine and cosmetics, as it is biocompatible, biodegradable, mucoadhesive, moisturizer, viscoelastic and biologically active. To slow down its degradation rate and implement its bioactivity, HA can be chemically modified to develop a number of costumized and more performing derivatives tailored for different applications. The aim of the present PhD thesis was to investigate the possible pharmaceutical and dermatologic/cosmetic applications of the novel urea-crosslinked hyaluronic acid (HA‑CL). First, an in vitro preliminary study showed

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Mofidfar, Mohammad. "POLYMERIC NANOFIBER/ANTIMICROBIAL FORMULATIONS USING A NOVEL CO-EXTRUSION APPROACH COMPARED WITH ELECTROSPINNING FOR TRANSDERMAL DRUG DELIVERY APPLICATIONS." Case Western Reserve University School of Graduate Studies / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1482512576465589.

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Hayavi, Sima. "Novel formulations for antigen delivery using biodegradable polymers: new approaches for the use of new and established adjuvants." Thesis, Aston University, 2002. http://publications.aston.ac.uk/12621/.

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The use of immunological adjuvants has been established since 1924 and ever since many candidates have been extensively researched in vaccine development. The controlled release of vaccine is another area of biotechnology research, which is advancing rapidly with great potential and success. Encapsulation of peptide and protein drugs within biodegradable microspheres has been amongst the most successful of approaches within the past decade. The present studies have focused on combining the advantages of microsphere delivery systems composed of biodegradable polylactide (PLLA) and polylactide-c

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Afrose, Afrina. "Crystallization engineering techniques for developing a novel dry powder inhaler formulation for ibuprofen." Thesis, Queensland University of Technology, 2017. https://eprints.qut.edu.au/107550/1/Afrina_Afrose_Thesis.pdf.

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The technique of producing inhalable particles (<5μm) for dry powder inhaler (DPI) formulations mostly involves crystallization followed by high energy input size reduction systems (e.g., milling and homogenization), which produces particles with very high surface energy and poor flow property that restricts the efficient dispersion of drug from the formulations. This investigation has used an anti-solvent precipitation crystallization (APC) method of producing inhalable ibuprofen (IBP) crystals for pulmonary delivery from a DPI formulation.

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Louisy, Jérémie. "Synthesis of novel phosphinate salts and development of formulations for the flame retardancy of glass fiber reinforced PolyButylene Terephthalate (PBT)." Thesis, Lille 1, 2012. http://www.theses.fr/2012LIL10162/document.

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Cette étude s’intéresse aux procédés d’ignifugation d’un thermoplastique, le PolyButylène Téréphthalate (PBT), et plus particulièrement à l’ajout en masse de retardateurs de flamme à base de phosphore. L’objectif de ce projet consiste à mettre au point une formulation PBT renforcée avec des fibres de verre et ignifugée en vue d’application dans le domaine électrique et électronique. Dans un premier temps, les propriétés au feu de différents additifs combinés à un sel de diethylphosphinate d’aluminium commercial sont évaluées. Différents sels de phosphinate dérivés de l’acide carboxyethyl(methy

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Kelchen, Megan N. "Topical treatment of infantile hemangiomas: in vitro evaluation of novel beta-blocker formulations and in vivo characterization of lesional skin." Diss., University of Iowa, 2018. https://ir.uiowa.edu/etd/6444.

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Infantile hemangiomas (IHs), benign vascular lesions present on the surface of the skin of children, are treated with systemic or topical beta-adrenergic antagonists (known as “beta-blockers”). However, systemic beta-blocker therapy is associated with serious adverse events in pediatric patients, and there are currently no topical formulations optimized for the skin. The objectives of this work were to 1) evaluate the local skin concentrations and drug permeation through the skin using novel beta-blocker formulations, and 2) characterize the epidermal properties and skin surface inflammatory m

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Terveer, Nils [Verfasser], Ulrike [Gutachter] Holzgrabe, and Lorenz [Gutachter] Meinel. "Springs and Parachutes - Development and Characterization of Novel Formulations for Poorly Water-Soluble Drugs / Nils Terveer ; Gutachter: Ulrike Holzgrabe, Lorenz Meinel." Würzburg : Universität Würzburg, 2017. http://d-nb.info/1144181224/34.

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Smith, Johan. "A comparison of synthetic surfactants : evaluation of a novel surfactant (1,2-dipalmitoyl-sn-phosphatidycholine and trehalose [C12H22O11]) and comparison with other synthetic formulations." Thesis, Stellenbosch : Stellenbosch University, 2002. http://hdl.handle.net/10019.1/52624.

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In title 12, 22, 11 are in subscript.<br>Thesis (PhD)--Stellenbosch University, 2002.<br>ENGLISH ABSTRACT: The aim of this study was to test a synthetic protein-free surfactant preparation, LPM-l, with the same chemical composition as commercially available Exosurf (Glaxo Wellcome), but containing in addition, a sugar, trehalose (TRE). Towards this end, a study was designed to firstly test the hypothesis that the true difference in acute physiological effects between a mixture of oppe, tyloxapol, hexadecanol and trehalose (LPM-l), and Exosurf, (Oppe, tyloxapol and hexadecanol) is zero, i

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Telford, Richard. "The Physical Chemistry of pMDI Formulations Derived from Hydrofluoroalkane Propellants. A Study of the Physical Behaviour of Poorly Soluble Active Pharmaceutical Ingredients; Bespoke Analytical Method Development Leading to Novel Formulation Approaches for Product Development." Thesis, University of Bradford, 2013. http://hdl.handle.net/10454/10098.

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Active Pharmaceutical Ingredients (APIs) are frequently prepared for delivery to the lung for local topical treatment of diseases such as Chronic Obstructive Pulmonary Disease (COPD) and asthma, or for systemic delivery. One of the most commonly used devices for this purpose is the pressurised metered dose inhaler (pMDI) whereby drugs are formulated in a volatile propellant held under pressure. The compound is aerosolised to a respirably sized dose on actuation, subsequently breathed in by the user. The use of hydrofluoroalkanes (HFAs) in pMDIs since the Montreal Protocol initiated a move away

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Wills, Peter. "Novel biocidal formulation." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/novel-biocidal-formulation(776ed624-6717-496f-9b31-ad2edce8e24b).html.

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In this modern age, society has become much more aware of the danger bacteria can have on people's health. Personal and household antimicrobial formulations are commonly used within the home to lower the levels of harmful bacteria such as E. Coli, Salmonella and Pseudomonas. The active which kills the bacteria within the formulation is described as a biocide. This research looks at the often neglected potential of cationic polyelectrolyte as a biocide, firstly within solution and secondly in creating an antimicrobial surface. The solution properties and antimicrobial activity for a range of co

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Price, Daniel Joseph [Verfasser], Jennifer [Akademischer Betreuer] Dressman, Christoph [Akademischer Betreuer] Saal, Martin [Akademischer Betreuer] Kuentz, Anita [Akademischer Betreuer] Nair, and Jennifer [Gutachter] Dressman. "Novel in vitro and in silico tools for the development of mesoporous silica formulations with optimal precipitation inhibitors / Daniel Joseph Price ; Gutachter: Jennifer Dressman ; Jennifer Dressman, Christoph Saal, Martin Kuentz, Anita Nair." Frankfurt am Main : Universitätsbibliothek Johann Christian Senckenberg, 2021. http://d-nb.info/1238143725/34.

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Lau, Kent G. "Formulation of novel double-chain lipid vesicles." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272376.

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Rabizadegan, Mariam. "Pre-formulation of a novel nucleotide analogue." Thesis, KTH, Skolan för kemi, bioteknologi och hälsa (CBH), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-278825.

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Previous studies have shown that the molecule MR1, a cGMP analogue, may be a suitable drug for neurodegenerative eye diseases. These diseases cause the eyesight to greatly deteriorate which in turn can result in the patient becoming blind. In this thesis, several salt forms of MR1 were synthesized and characterized to generate the drugs physicochemical properties, such as solubility and solid-state behavior. This in order to determine the drugs pre-formulation data. Synthesis of MR1 Na+ and MR1 Free form were performed in order generate material for solubility studies and solid state character

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42

Patel, Asma. "Formulation studies and development of novel anticancer prodrugs." Thesis, De Montfort University, 2007. http://hdl.handle.net/2086/7981.

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Abushrida, Ahmed. "Formulation of novel polymer coated iron oxide nanoparticles." Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/12537/.

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The aim of this study was to investigate how to produce iron oxide nanoparticles, with the potential for long circulation times or the ability to preferentially reach particular tissues. The preparation of iron oxide nanoparticles was achieved using inorganic solution methods to prepare particles of small size using a narrow size distribution. The nanoparticles were coated with dextran and carboxymethyl dextran as reference materials using the same method as in the preparation of the iron oxide nanoparticles. This project investigated the use of the biodegradable polymer poly(glycerol adipate)

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Benetton, Salete Aparecida. "Formulation of novel surfactant vesicles for dermatological drug delivery." Thesis, University of Strathclyde, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249817.

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Etherson, Kelly. "Novel formulation strategies to overcome poorly water soluble compounds." Thesis, University of Strathclyde, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678251.

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Drug solubility plays an important role during formulation development; it affects drug delivery and, as many new drug candidates developed have poor water solubility, it is necessary to increase their aqueous solubility for administration. The solubility increases, achieved by prodrugs or salt formation for example, are traditionally measured using the shake-flask method. This thesis investigated the advantages of the CheqSol method for phase-solubility studies. This method, using small pH changes, brings a compound close to its intrinsic solubility then alternates the system between sub- and

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Mackilligin, Harry. "The investigation, creation and formulation of novel thermochromic coatings." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/43235/.

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Rolls-Royce is a well reputed and multinational company that develops and manufactures propulsion systems including gas turbines for many applications, with aerospace being the most well-known. In the process of developing new turbine engines to power ever larger, more efficient and environmentally friendly aircraft, the conditions within their engines are pushing the boundaries of what was previously thought possible. One of the major factors that needs to be considered and controlled in the engine development is the temperature at which the engine components are exposed to. Currently, temper

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Geldenhuys, Brandon Lindsay. "Dissolution and antiviral activity of a novel nevirapine formulation." Thesis, University of the Western Cape, 2014. http://hdl.handle.net/11394/4653.

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Magister Pharmaceuticae - MPharm<br>The author’s objective was to follow the product life-cycle process of a novel antiretroviral, nevirapine formulation in South Africa, to generate and compile data to pursue market registration. Five supramolecular co-crystals, viz. nevirapine-saccharin (NVSC), nevirapine-DL-tartaric acid (NVTTA), nevirapine-maleic acid (NVMLE), nevirapine-glutaric acid (NVGLT) and nevirapine-salicylic acid (NVSLI) were reproduced and confirmed by powder X-ray diffraction (PXRD). A pre-formulation study ensued to identify the most appropriate co-former candidate to formulate

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Fransén, Nelly. "Studies on a Novel Powder Formulation for Nasal Drug Delivery." Doctoral thesis, Uppsala universitet, Institutionen för farmaci, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9292.

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Nasal administration has potential for the treatment of indications requiring a fast onset of effect or for drugs with low oral bioavailability. Liquid nasal sprays are relatively common, but can be associated with suboptimal absorption from the nasal cavity; this thesis shows that nasal absorption can be significantly enhanced with a dry powder formulation. It was shown that interactive mixtures, consisting of fine drug particles adhered to the surface of mucoadhesive carrier particles, could be created in a particle size suitable for nasal administration. Sodium starch glycolate (SSG), a com

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Perkins, Mark. "A novel surface analytical approach for understanding herbicide formulation performance." Thesis, University of Nottingham, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.431879.

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Uribe, Wandurraga Zaida Natalia. "Microalgae as novel ingredients for the formulation of food products." Doctoral thesis, Universitat Politècnica de València, 2021. http://hdl.handle.net/10251/158743.

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[ES] Las microalgas son organismos unicelulares fotosintéticos microscópicos que se encuentran en gran variedad de ambientes y son muy eficientes en la transformación de energía solar en biomasa. Los estudios realizados hasta el momento hacen referencia a posibles beneficios de la incorporación de microalgas en la dieta, por la mejora del sistema cardiovascular, las propiedades adelgazantes y energizantes, capacidad antioxidante, o la reducción del colesterol y los triglicéridos. La forma más habitual de consumir las microalgas es como suplemento dietético en forma de tabletas, cápsulas o polv

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