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Rozprawy doktorskie na temat „NP (Nanoparticle)”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Hiremath, Jagadish. "Development and Evaluation of PLGA-Nanoparticle Entrapped Influenza Virus Peptides Vaccine and Effect on Molecular Phenotype of Alveolar Macrophages with reference to DAP12 Signaling Pathway in Pigs." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1429817903.

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Nastiti, Christofori Maria Ratna Rini. "Development and evaluation of polymeric nanoparticle formulations for triamcinolone acetonide delivery." Thesis, Curtin University, 2007. http://hdl.handle.net/20.500.11937/613.

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The aims of this study were to develop polymeric NP formulations for triamcinolone acetonide (TA) delivery, from biodegradable and biocompatible hydrophobic polymers, which provide sustained release, prolonged stability and low toxicity, and to assess the toxicity of TA NPs (TA-NPs) compared to TA alone upon BALB/c 3T3 and ARPE 19 cell culture models.The study involved investigation of three different types of polymers: poly(D,L,lactide) (PDLLA), poly(D,L,lactide-co-glycolide)(PLGA) and methoxypolyethyleneglycol poly(D,L,lactide-co-glycolide)(mPEG PLGA). Two different methods were studied in t

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CARDELLINI, ANNALISA. "Modelling of Multi-Scale Phenomena in Nanoparticle Suspensions." Doctoral thesis, Politecnico di Torino, 2017. http://hdl.handle.net/11583/2687171.

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Self- or driven-assembly of nanoparticles (NPs) into mesoscopic ordered structures play a crucial role in a large variety of applications including energy, pharmaceutical, food, drug delivery, immunology and technological. On the one hand, trying to prevent and avoid the self-organization of nanoparticles has traditionally been the main issue to stabilizing nanosuspensions, foams, and emulsions. On the other hand, the aggregation of building-blocks into mesoscopic structures has allowed to explore new materials with desired functionalities and properties. In the latter context, a proper atten

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Cao, Xue-Zheng, Holger Merlitz, Chen-Xu Wu, Goran Ungar, and Jens-Uwe Sommer. "A theoretical study of dispersion-to-aggregation of nanoparticles in adsorbing polymers using molecular dynamics simulations." Royal Society of Chemistry, 2016. https://tud.qucosa.de/id/qucosa%3A36333.

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The properties of polymer–nanoparticle (NP) mixtures significantly depend on the dispersion of the NPs. Using molecular dynamics simulations, we demonstrate that, in the presence of polymer–NP attraction, the dispersion of NPs in semidilute and concentrated polymers can be stabilized by increasing the polymer concentration. A lower polymer concentration facilitates the aggregation of NPs bridged by polymer chains, as well as a further increase of the polymer–NP attraction. Evaluating the binding of NPs through shared polymer segments in an adsorption blob, we derive a linear relationship betwe

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Williams, Kelley J. "Silver Nanoparticles Inhibit the Binding and Replication of Dengue Virus." Wright State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=wright1431880664.

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Galliani, Marianna. "Design of a versatile nanoparticle-based delivery system for intracellular and in vivo-targeted protein replacement therapy." Doctoral thesis, Scuola Normale Superiore, 2019. http://hdl.handle.net/11384/85931.

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Protein replacement therapy is to-date one of the main clinical approaches to treat a wide number of diseases that are correlated to a protein dysfunction or absence. However, the systemic administration of proteins rarely translates into a successful therapy, due to the fragile nature of these molecules and their inability to reach specific targets in vivo. Pharmaceutical technology strategies such as the encapsulation into a nanovector could overcome the limits of protein administration, since nanovectors can protect the payload from degradation and rapid clearance, and they can be f

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Binjawadagi, Basavaraj. "DEVELOPMENT AND EVALUATION OF NOVEL INTRANASAL VACCINATION STRATEGIES TO PREVENT PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME IN PIGS." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1429797731.

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Tyrrell, Christina Holly. "A Lateral Flow Smart Phone Image Analysis Diagnostic." DigitalCommons@CalPoly, 2013. https://digitalcommons.calpoly.edu/theses/1083.

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A low cost compact diagnostic has many implications in today’s society. Smart phone technology has exponentially grown and with it the imaging capabilities associated with smart phones. The goals of this research are i) to determine the feasibility of combining in the field smart phone images with color dependent assay results, ii) to develop a MatLab® image analysis code to analyze these results, and iii) compare limits of detection between the un-aided eye and MatLab® image analysis software. Orange G dye is used to create a stock solution and subsequent titers for analysis. Autocad is used

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VALENTE, STEFANO. "Hybrid Nanoparticles for Theranostics: Design, Synthesis and Characterization." Doctoral thesis, Università degli Studi di Trieste, 2021. http://hdl.handle.net/11368/2996079.

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The last decades have witnessed the foundation and the ascent of a novel discipline that applies the innovation in nanotechnology and material sciences to medicine and biology: nanomedicine. The current trend in one of the major subfields of nanomedicine is the development of “theranostic” nanosystems, devices designed to be employed both for the diagnosis and the treatment of specific pathologies. Within the context of nanomedicine, this PhD thesis work addressed the clinical need for novel theranostic alternatives and proposed two different designs for hybrid organic-inorganic theranostic na

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Housni, Sofia. "Floculation magnétiquement assistée appliquée au traitement des eaux : étude d’un système modèle argile/NP de maghémite." Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS334.

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Les questions liées à la pollution croissante des ressources en eau sont devenues un enjeu sociétal de grande importance qui a conduit les chercheurs et les industriels à se focaliser sur la mise au point de nouveaux procédés de traitement de l’eau plus efficaces et plus rapides. L’une des étapes clefs du traitement de l’eau est la floculation : il s’agit d’un processus physico-chimique au cours duquel des particules colloïdales devant être éliminées (bactéries, matière organique naturelle, argiles…) vont s’agglomérer pour former des particules plus grosses appelées flocs. Cette étape est décl

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11

Zhang, Furui. "Mechanism and Interface Study of One-to-one Metal NP/Metal Organic Framework Core-shell Structure." Thesis, Boston College, 2017. http://hdl.handle.net/2345/bc-ir:107565.

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Thesis advisor: Chia-Kuang (Frank) Tsung<br>The core-shell hybrid structure is the simplest motif of two-component systems which consists of an inner core coated by an outer shell. Core-shell composite materials are attractive for their biomedical, electronic and catalytic applications in which interface between core and shell is critical for various functionalities. However, it is still challenging to study the exact role that interface plays during the formation of the core-shell structures and in the properties of the resulted materials. By studying the formation mechanism of a well interfa

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PISANI, ANISSA. "Chemokine functionalized nanoparticles interactions with acute monocytic leukemia cells." Doctoral thesis, Università degli studi di Genova, 2022. http://hdl.handle.net/11567/1073264.

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Biodegradable nanoparticles (NPs) aimed at drug/gene delivery can be functionalized with different molecules to have specific characteristics, like short bio-persistence, protection of the NP cargo and controlled release, specific cell/tissue targeting, as well as modulation of cellular signaling. To specifically improve NP selective targeting and modulation of immune responses, I focused my PhD project on the interactions between biocompatible NPs and immune cells. This goal was pursued by PLGA/Pluronic NP-surface decoration with two different chemokines, namely CXCL12 and CCL5. The first is

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Moscu, Corcodel Alina. "Structural transformation under reaction conditions of supported PtSn nanoparticles characterized by in situ DRIFTS and kinetic modeling." Thesis, Lyon 1, 2015. http://www.theses.fr/2015LYO10177.

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La réaction d’oxydation sélective du CO par O2 en présence d’un excès d’hydrogène (PROX) est considérée comme une étape de purification essentielle de l’H2 à utiliser dans des piles à combustible. L’objectif de cette thèse est de mieux comprendre le mécanisme de cette réaction sur des catalyseurs bimétallique s à base de Pt et Sn. Des catalyseurs modèles Pt et Pt-Sn ont été synthétisés en deux étapes : (i) formation de nanoparticules (NP) métalliques colloïdales en suspension suivi par ( ii) l’imprégnation de ces particules sur des supports. L’adsorption du CO suivit par spectroscopie FT-IR en

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Dazzazi, Anass. "Synthèse et caractérisation de nanoparticules d'oxydes métalliques par voie organométallique : vers des applications biomédicales." Toulouse 3, 2013. http://thesesups.ups-tlse.fr/1951/.

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Le travail présenté dans ce manuscrit s'inscrit dans un projet collaboratif entre l'Université de Toulouse et l'Université de Rabat. Le sujet porte sur le développement de nanoparticules d'oxydes métalliques (gamma-Fe2O3 et ZnO) pour des applications biomédicales (IRM et imagerie optique). Il s'agit en particulier de développer des approches permettant de rendre hydrophiles des nanoparticules hydrophobes synthétisées par voie organométallique et d'en étudier les propriétés. Dans un premier temps, des méthodologies d'échange de solvant pour transférer des nanoparticules de ZnO hydrophobes dans

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15

Gonçalves, Lidiane Patricia. "Ormosils fotoativos com fosfotungstato dopados com nanopartículas SiO2@TiO2 e NP de Ag: avaliação fotocrômica e potencial de inibição bactericida frente às bactérias Staphylococcus aureus e Pseudomona aeruginosa." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/18/18158/tde-03082016-135355/.

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Neste trabalho foram preparados materiais híbridos do tipo silicatos organicamente modificados (Ormosils) contendo fosfotungstato, [PW12O40]-3 e dopados com nanopartículas sintetizadas core@shell SiO2@TiO2. Os objetivos a serem atingidos com estes materiais são obter filmes com alta sensibilidade à radiação UV e capazes de fotossintetizar nanopartículas de Ag no seu interior e superfície visando revestimentos antibacterianos. O pigmento fotocrômico nos filmes é o fosfotungstato e o core@shell irá atuar como agente potencializador da resposta fotocrômica dele. Dessa maneira variou-se a quantida

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16

Almeida, Raquel Mariano de. "Estudo espectroscópico de anticorpos empregando-se superfícies SERS-ativas visando o desenvolvimento de imunossensores." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/46/46136/tde-17082016-081010/.

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Este estudo empregou anticorpos que podem ser peças chaves no eventual desenvolvimento de imunossensores, devido as suas características de seletividade e consequente determinação de espécies de interesse em análises clínicas, ambiental, saúde publica, entre outros. Para isto, foram feitos estudos de espectros Raman e SERS de anticorpos inteiros e/ou fragmentados (IgG humana, anti-IgG humana (H+L) e anti-IgG humana (Fab2)). Com isto, foram conhecidos os principais modos vibracionais destas biomoléculas que são úteis para a proposta de se construir imunossensores. Ambas as técnicas fornecem inf

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17

Lepcio, Petr. "Efekt submikrometrických rysů na reologii polymerních nanokompozitů." Doctoral thesis, Vysoké učení technické v Brně. CEITEC VUT, 2018. http://www.nusl.cz/ntk/nusl-391876.

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Polymerní nanokompozity (PNCs) mají slibnou budoucnost jako lehké funkční materiály zpracovatelné aditivními výrobními technologiemi. Jejich rychlému rozšíření však brání silná závislost jejich užitných vlastností na prostorovém uspořádání nanočástic (NP). Schopnost řídit disperzi nanočástic je tak klíčovým předpokladem pro jejich uplatnění ve funkčních kompozitech. Tato práce zkoumá přípravu polymerních nanokompozitů v modelové sklotvorné polymerní matrici roztokovou metodou, technikou schopnou vytvářet prostorové uspořádání nanočástic řízené strukturními a kinetickými parametry přípravného p

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18

Marepally, Bhanu Chandra. "Production of Solar Fuels using CO2." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSE1062.

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Compte tenu du récent taux alarmant d'épuisement des réserves de combustibles fossiles et de l'augmentation drastique des niveaux de CO2 dans l'atmosphère qui a conduit au réchauffement de la planète et à des changements climatiques sévères, l'exploitation de toutes sortes d'énergies renouvelables a été la Parmi les principales priorités de la recherche Champs à travers le monde. L'une des nombreuses voies de ce genre est la réduction du CO2 aux combustibles utilisant des énergies renouvelables, plus communément appelées cellules photoélectro-catalytiques (PEC). Des essais expérimentaux sur la

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Behafarid, Farzad. "Structure, stability, vibrational, thermodynamic, and catalytic properties of metal nanostructures: size, shape, support, and adsorbate effects." Doctoral diss., University of Central Florida, 2012. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/5121.

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Recent advances in nanoscience and nanotechnology have provided the scientific community with exciting new opportunities to rationally design and fabricate materials at the nanometer scale with drastically different properties as compared to their bulk counterparts. In this dissertation, several challenges have been tackled in aspects related to nanoparticle (NP) synthesis and characterization, allowing us to make homogenous, size- and shape-selected NPs via the use of colloidal chemistry, and to gain in depth understanding of their distinct physical and chemical properties via the synergistic

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Motaragheb, Jafarpour Saeed. "Investigation of multicomponent catalyst systems for type-selective growth of SWCNTs by CVD." 2019. https://monarch.qucosa.de/id/qucosa%3A38384.

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Excellent electronic properties of semiconducting single-walled carbon nanotubes (sc-SWCNTs) motivated the investigation for using them in different application areas such as microelectronics, sensorics, MEMS and MOEMS. However, challenges arise from the lack of selectivity with respect to electronic type and chirality as well as ensuring high quality, high purity and well-aligned SWCNTs during fabrication process. Catalytic chemical vapour deposition (CCVD) has shown great potential in direct synthesis of high quality SWCNTs with chiral or type selectivity. This thesis addresses three importa

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Yeh, Yu-Lun, and 葉佑倫. "Nitrogen CNTs-Pt nanoparticles for Catalytic Reduction of 4-Nitrophenol (4-NP)." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/tb5k65.

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碩士<br>國立臺灣科技大學<br>化學工程系<br>106<br>Heteroatom doping carbon materials can endow many properties. The improved features can be widely applied in different field. In this thesis, we follows our laboratory has previously developed an effective method to doping boron and nitrogen into the carbon nanotubes under atmospheric pressure, by controlling the temperature to achieve different levels of nitrogen content, and deposit the metal nanoparticles with high specific surface area and high activity on the tubes. The formation of nanocomposite as a catalyst to apply the reduction reaction of 4-nitrophe

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Islam, I., M. Khan, Xiangli Liu, A. Parmar, and Lijun Shang. "Comparative responses of human keratinocyte cells (HaCaT) and human lung carcinoma epithelial cells (A549) following in vitro exposure to Silicon dioxide nanoparticles (SiO2-NP)." 2015. http://hdl.handle.net/10454/10489.

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No<br>The use of nanoparticles have provided numerous of advantages in medicine due to their unique physiochemical characteristics such as size, charge, shape and surface reactivity [1-4]. Understanding the interaction between engineered nanomaterials and living matter has attracted increasing attention in recent years. Toxicity of nanoparticles was studied in different cell types and cell lines. Nano-SiO2 has good stability, easy dispensability, and melting degeneration, and is widely used in rubber, paints, biomedical and biotechnology fields [5]. In this study, the LDH assay and the MTT ass

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