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Artykuły w czasopismach na temat „Nut Asia Betel-quid epidemiology”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Gupta, PC, and CS Ray. "Epidemiology of Betel Quid Usage." Annals of the Academy of Medicine, Singapore 33, no. 4 Suppl (2004): 31S—36S. http://dx.doi.org/10.47102/annals-acadmedsg.v33n4p31s.

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Betel quid chewing is an ancient practice common in many countries of Asia and among migrated communities in Africa, Europe and North America. It enjoys complete social acceptance in many societies and is also popular among women. In its most basic form, betel quid consists of betel leaf (Piper betel), areca nut, the main psychoactive ingredient, and slaked lime (calcium hydroxide). Areca nut is said to be the fourth most commonly used psychoactive substance in the world, after caffeine, nicotine and alcohol. There are a great variety of ingredients and ways of preparing betel quid in differen

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Abbas, Tabarak Sabah, Dhaneen Mahdi, Marwah Safaa Ali, and Ali A. Al-fahham. "Etiology, Epidemiology and Pathophysiology of Oral Squamous Cell Carcinoma: A Review Article." International Journal of Medical Science and Dental Health 11, no. 06 (2025): 179–84. https://doi.org/10.55640/ijmsdh-11-06-20.

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Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity. It accounts for more than 90% of oral cancers and is ranked as the sixth most prevalent cancer when considered on a global scale. In terms of pathogenesis, genetic, epigenetic, and environmental factors play a role in their interaction. Well-established risk factors are smoked tobacco, alcohol drinking, betel quid chewing, and high-risk human papillomavirus (HPV) infection- especially HPV-16. From these exposures mutate key oncogenes and tumor suppressor genes such as RAS, MYC, and TP53 plus promoter hypermet

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Barsouk, Adam, John Sukumar Aluru, Prashanth Rawla, Kalyan Saginala, and Alexander Barsouk. "Epidemiology, Risk Factors, and Prevention of Head and Neck Squamous Cell Carcinoma." Medical Sciences 11, no. 2 (2023): 42. http://dx.doi.org/10.3390/medsci11020042.

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Head and neck squamous cell carcinoma (HNSCC) is a group of malignancies, involving the oral cavity, pharynx, hypopharynx, larynx, nasal cavity, and salivary glands, that together compose the seventh most common cancer diagnosis worldwide. With 890,000 new cases and 450,000 deaths annually per GLOBOCAN estimates, HNSCC accounts for roughly 4.5% of cancer diagnoses and deaths. In the developing world, the incidence of HNSCC is growing with increasing consumption of tobacco (smoked or chewed), alcohol, and areca nut (betel quid). Alcohol and tobacco have a synergistic effect, with the heavy cons

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Reza Agustina, Amirah Mujahidah, and Titiek Berniyanti. "Betel nut chewing effects on the incidence of periodontitis." World Journal of Advanced Research and Reviews 23, no. 3 (2024): 540–43. http://dx.doi.org/10.30574/wjarr.2024.23.3.2606.

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Background: Betel quid chewing, a common cultural practice in various parts of Asia, has been associated with numerous oral health issues, including periodontitis. Betel quid chewing, which involves the consumption of a mixture of areca nut, lime, betel leaf, and sometimes tobacco, is a common practice in several Asian countries, including Indonesia. Several studies have indicated a connection between this habit and various oral health problems, including periodontitis, a chronic inflammatory condition affecting the supporting tissues of the teeth. This systematic literature review aims to exp

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Reza, Agustina, Mujahidah Amirah, and Berniyanti Titiek. "Betel nut chewing effects on the incidence of periodontitis." World Journal of Advanced Research and Reviews 23, no. 3 (2024): 540–43. https://doi.org/10.5281/zenodo.14928803.

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<strong>Background: </strong>Betel quid chewing, a common cultural practice in various parts of Asia, has been associated with numerous oral health issues, including periodontitis. Betel quid chewing, which involves the consumption of a mixture of areca nut, lime, betel leaf, and sometimes tobacco, is a common practice in several Asian countries, including Indonesia. Several studies have indicated a connection between this habit and various oral health problems, including periodontitis, a chronic inflammatory condition affecting the supporting tissues of the teeth. This systematic literat

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Koesbardiati, Toetik, and Delta Bayu Murti. "KONSUMSI SIRIH PINANG DAN PATOLOGI GIGI PADA MASYARAKAT PRASEJARAH LEWOLEBA DAN LIANG BUA, DI NUSA TENGGARA TIMUR, INDONESIA." Berkala Arkeologi 39, no. 2 (2019): 121–38. http://dx.doi.org/10.30883/jba.v39i2.470.

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This paper focus on chewing betel quid habit that dominantly happen in the Asia to Pacific region. Betel quid leaves traces of reddish-brown colour on the teeth. It was identified that dental stain was very common on teeth of prehistoric skeletal remains, for example in Thailand and Vietnam. Several studies have shown that chewing betel nut can cause diseases in the teeth and oral cavity. The purpose of this study is to describe the relationship between betel nut chewing and the emergence of tooth pathology in teeth from the prehistoric population from Lewoleba and Liang Bua. Ten individuals w

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Chen, Xiaoxiao, Yongzhi He, and Yanru Deng. "Chemical Composition, Pharmacological, and Toxicological Effects of Betel Nut." Evidence-Based Complementary and Alternative Medicine 2021 (August 18, 2021): 1–7. http://dx.doi.org/10.1155/2021/1808081.

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Betel nut, the fruit of Areca catechu L, has a long medical history in Southeast Asia. It is native to Malaysia and is cultivated and processed extensively in subtropical regions, such as South China and India. Betel nut almost appears as a “snack” in various occasions in most parts of China. Clinically, betel nut can play a certain pharmacology role and was used in malaria, ascariasis, arthritis, enterozoic abdominalgia, stagnation of food, diarrhea, edema, and beriberi. The nervous excitement of betel nut chewing has made it gradually become popular. However, chewing betel nut can induce ora

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Shrestha, A. "Approaches and Strategies for Habit Intervention in Smokeless Tobacco/Arecanut/ Betel Quid and Non-Starting." Journal of Global Oncology 4, Supplement 2 (2018): 20s. http://dx.doi.org/10.1200/jgo.18.45200.

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Background: Although adequate research has been conducted regarding smoking and smokeless tobacco, there is a dearth of research exploring reasons for chewing areca nut and betel-quid. Global epidemiology of areca nut and betel-quid shows distinct ethnic and cultural preferences. Areca nut is chewed for its psychological stimulating effects and perhaps, a medicinal value. To develop empirically supported treatments and to promote nonstarting, healthcare workers and researchers must first understand the reasons people engage in the behavior. Aim: To discuss evidence based approaches and strateg

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Bali, Dr Sharadendu. "Paan – A Mouthful of Betel Leaf Packaged Ambrosia for Good Health." Scholars Journal of Applied Medical Sciences 13, no. 01 (2025): 104–29. https://doi.org/10.36347/sajb.2025.v13i01.012.

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The chewing of sachet-like betel leaf quids, packing various spicy and flavoured ingredients in a folded betel leaf, is a customary practise in a number of nations of South Asia. The betel leaf munchie (paan), most popularly chewed after meals, has been much berated and unfairly scorned, as it is thought to produce detrimental effects on the body. This dogma about the harmful effects of paan has been upended by recent studies demonstrating the beneficial impact of betel phytochemicals on several body functions, as well as on the gut microbiota. Moreover, the advantageous effects of the health-

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Marzan, Abdullah, Md Hasan, Md Islam, et al. "Impact of Betel quid on hyperglycaemia among diabetes patients in Bangladesh." Journal of Advanced Biotechnology and Experimental Therapeutics 7, no. 3 (2024): 460. http://dx.doi.org/10.5455/jabet.2024.d40.

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This study explores the impact of betel quid (BQ) chewing on hyperglycaemia among diabetic patients in northeastern Bangladesh. BQ, a prevalent social habit in Asia, is often used without awareness of its harmful effects. We focus on the role of areca nut, a key addictive component in BQ, in influencing hyperglycaemia. Random blood glucose (RBG) tests were conducted on 961 diabetic patients, alongside lifestyle data, from August 2018 to February 2019 at Sylhet Diabetic Hospital, Bangladesh. Statistical analyses, including t-tests, Analysis of the variance (ANOVA), Fisher's exact test, and Mult

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Bhatta, Rishi, and M. Pyakurel. "Clinical profile and oral sub mucous fibrosis." Nepalese Journal of ENT Head and Neck Surgery 5, no. 1 (2017): 5–7. http://dx.doi.org/10.3126/njenthns.v5i1.16851.

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Objectives: Oral submucous fibrosis (OSMF) is an insidious precancerous disease mostly seen in the Southeast Asia. This paper aims to study on clinical profile of patients with OSMFMaterial and Methods: This cross sectional study was done in department of ENT and HNS, Nepalgunj Medical College and Teaching Hospital. In outpatient department patients with OSMF were ask to fill up a questionnaire that included identification of patient, occupation, their symptoms and habit of taking betel quid or paan, gutkha, etc. Oral cavity was examined and lesion along with its extent and severity was noted.

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Molla, Motiur R., Mausumi Iqbal, Md Nazrul Islam, and Akhilanand Chaurasia. "Epidemiology of surgically treated oral cancer patients in a tertiary care hospital in Bangladesh: A retrospective study." National Journal of Maxillofacial Surgery 16, no. 1 (2025): 140–44. https://doi.org/10.4103/njms.njms_197_23.

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Background: Oral cancer is the third most common cancer and a major health issue in Bangladesh. This study aimed to see the prevalence rate, age, site of involvement, gender and its relation with habits, histopathological grading, staging of diseases, and lymph node status. Material and Methods: Biopsy-proven oral cancer patients registered in the Oral and Maxillofacial Surgery unit of Anwer Khan Modern Medical College and Hospital, Dhaka, Bangladesh, affiliated with the University of Dhaka under the Faculty of Medicine. Patients included in this study were all surgically treated during 2017 t

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13

Zhang, Pangzhen, Nathaniel Quan En Chua, Simon Dang, et al. "Molecular Mechanisms of Malignant Transformation of Oral Submucous Fibrosis by Different Betel Quid Constituents—Does Fibroblast Senescence Play a Role?" International Journal of Molecular Sciences 23, no. 3 (2022): 1637. http://dx.doi.org/10.3390/ijms23031637.

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Betel quid (BQ) is a package of mixed constituents that is chewed by more than 600 million people worldwide, particularly in Asia. The formulation of BQ depends on a variety of factors but typically includes areca nut, betel leaf, and slaked lime and may or may not contain tobacco. BQ chewing is strongly associated with the development of potentially malignant and malignant diseases of the mouth such as oral submucous fibrosis (OSMF) and oral squamous cell carcinoma (OSCC), respectively. We have shown recently that the constituents of BQ vary geographically and that the capacity to induce dise

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Swain, Santosh Kumar. "Premalignant lesions of the oral cavity: current perspectives." International Journal of Research in Medical Sciences 9, no. 6 (2021): 1816. http://dx.doi.org/10.18203/2320-6012.ijrms20212259.

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Premalignant lesions of the oral cavity are also called as potentially malignant disorders. The common premalignant lesions of the oral cavity include leukoplakia, oral submucous fibrosis (OSMF) and oral erythroplakia. These lesions have a very high malignant transformation rate. The exact etiological factors for development of the premalignant lesions of the oral cavity are not fully understood till date. Use of tobacco, alcohol drinking, chewing betel quid containing areca nut and solar rays are important etiological factors for resulting the premalignant lesions of the oral cavity. Early di

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Senevirathna, Kalpani, Roshan Pradeep, Yovanthi Anurangi Jayasinghe, et al. "Carcinogenic Effects of Areca Nut and Its Metabolites: A Review of the Experimental Evidence." Clinics and Practice 13, no. 2 (2023): 326–46. http://dx.doi.org/10.3390/clinpract13020030.

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Oral cancers (OC) are among the most frequent malignancies encountered in Southeast Asia, primarily due to the prevalent habit of betel quid (BQ) and smokeless tobacco use in this region. Areca nut (AN), the primary ingredient in BQ, contains several alkaloids, including arecoline, arecaidine, guvacoline, and guvacine. These have been associated with both the AN abuse liability and carcinogenicity. Additionally, variations in AN alkaloid levels could lead to differences in the addictiveness and carcinogenic potential across various AN-containing products. Recent studies based on animal models

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Narang, Ramandeep S. "Oral Submucous Fibrosis: An Overview." AMEI's Current Trends in Diagnosis & Treatment 1, no. 1 (2017): 22–26. http://dx.doi.org/10.5005/jp-journals-10055-0005.

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ABSTRACT Oral submucous fibrosis (OSMF) is a chronic and potentially malignant condition of the oral cavity. It occurs predominantly in India and Southeast Asia. The pathogenesis of OSMF is not well established, but it is believed to be multifactorial. Chewing of betel quid (containing areca nut, tobacco, and slaked lime) has been recognized as one of the most important risk factors. It is characterized by a juxtaepithelial inflammatory reaction followed by fibroelastic changes in the lamina propria and associated epithelial atrophy. The disease affects most parts of the oral cavity as well as

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Johnson, N. "Quantifying the Immense Burden of OPMDS and of Oral Cancer in South Asia: Time for Action." Journal of Global Oncology 4, Supplement 2 (2018): 125s. http://dx.doi.org/10.1200/jgo.18.20600.

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Background: Cancer of head and neck is sixth most common malignancy worldwide https://www.ncbi.nlm.nih.gov/pubmed/27245686 . ∼90% are squamous cell carcinomas [HNSCC]. Of H&N sites, mouth is most common [∼300,373 cases pa, cf oropharynx ∼142,387; larynx ∼156,877; nasopharynx 86,691]. Across south Asia, cancer of lip & mouth [oral cancer: OSCC] is a serious public health problem. In many, it is the most common cancer among men, 5th/6th in women, second overall. Five year survival rates are < 50%. Treatment is devastating. It is difficult to get authorities and public to recognize the

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Yang, Nai-Yen Jack, Krishna Kaphle, Pei-Hwa Wang, De-Shien Jong, Leang-Shin Wu, and Jen-Hsou Lin. "Effects of Aqueous Extracts of "Betel Quid" and Its Constituents on Testosterone Production by Dispersed Mouse Interstitial Cells." American Journal of Chinese Medicine 32, no. 05 (2004): 705–15. http://dx.doi.org/10.1142/s0192415x04002430.

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Betel quid (BQ) is a favorite chewing item among many communities in different parts of Asia where it is popular by different names. BQ is a unique combination of nut or fruit from the Areca catechu Linn. (AN) tree, leaf from the Piper betle Linn. (BL) vine, slaked lime, paste of bark from the Acacia catechu tree and other spices. AN has been used successfully in various traditional medicines by different civilizations over several ages. Initially condemned by the medical communities for its health hazards, identification and application of potent pharmacologically bioactive compounds from dif

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Talpur, Pireh, Muhammad Ali Panhwar, Bashir Ahmed Jalbani, et al. "Evaluation of Site And Location of Oral Squamous Cell Carcinoma among Patients Visiting at Tertiary Care Hospital Hyderabad." Journal of Health and Rehabilitation Research 4, no. 1 (2024): 1672–77. http://dx.doi.org/10.61919/jhrr.v4i1.710.

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Background: Oral Squamous Cell Carcinoma (OSCC), a prevalent form of oral cancer, is marked by its aggressive nature and potential for metastasis. With a global five-year survival rate below 50%, the incidence of OSCC presents a significant public health challenge. The highest incidence rates are observed in Southeast Asia, correlating with the cultural practices of betel-quid and tobacco consumption. Objective: To evaluate the common sites and locations of OSCC among patients attending a tertiary care hospital in Hyderabad, with a view to identifying patterns that may guide early detection an

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Lee, C. H., A. M. S. Ko, S. Warnakulasuriya, et al. "Intercountry prevalences and practices of betel-quid use in south, southeast and eastern asia regions and associated oral preneoplastic disorders: an international collaborative study by asian betel-quid consortium of south and east Asia." John Wiley & Sons, January 1, 2011. https://doi.org/10.5281/zenodo.811233.

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Health risks stemming from betel-quid (BQ) chewing are frequently overlooked by people. Updated epidemiological data on the increased BQ use among Asian populations using comparable data collection methods have not been widely available. To investigate the prevalence, patterns of practice and associated types of oral preneoplastic disorders, an intercountry Asian Betel-quid Consortium study (the ABC study) was conducted for Taiwan, Mainland China, Malaysia, Indonesia, Nepal and Sri Lanka. A random sample of 8,922 subjects was recruited, and the data were analyzed using survey-data modules adju

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Zain, R. B. "Cultural and dietary risk factors of oral cancer and precancer - A brief overview." Elsevier, January 1, 2001. https://doi.org/10.5281/zenodo.811195.

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This is an update on cultural and dietary risk factors for oral precancer and cancer. It is an overview on ethnic differences (where possible) and socio-cultural risk factors (tobacco/areca nut/betel quid, alcohol use and dietary factors) in relation to oral precancer and cancer. While studies were from Western countries, India and China, this update also attempts to include and highlight some studies conducted in the Asia-Pacific region. This record was migrated from the OpenDepot repository service in June, 2017 before shutting down.

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Aniket, Adhikari, and De Madhusnata. "RELATION WITH ORAL SQUAMOUS CELL CARCINOMA AND BETEL QUID: A MOLECULAR CYTOGENETICS STUDY." October 15, 2019. https://doi.org/10.5281/zenodo.3545671.

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Introduction: Betel quid (BQ) chewing is widely prevalent in India and many parts of Asia. The International Agency for Research on Cancer (IARC) has listed BQ as group 1 human carcinogen, related with multistage progression in oral squamous cell carcinoma (OSCC). Areca nuts, Catechu, Slaked lime with betel leaf are major components of Betel quid. Nitrosamines formed from alkaloids in betel nut may be implicated in the etiology of oral cancer. OSCC are characterized by complex karyotype that involves many chromosomal aberrations (CA). The CYPs families are involved in the metabolic activation

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Clark, Cali, Shane Miller, and Justin Wilberding. "Abstract 17593: Betel Quid Addiction Causing Monomorphic Ventricular Tachycardia." Circulation 148, Suppl_1 (2023). http://dx.doi.org/10.1161/circ.148.suppl_1.17593.

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A 44-year-old woman presented to the emergency room due to worsening shortness of breath over the past few days with accompanying dizziness, cough, and fever. Her history was significant for asthma, obstructive sleep apnea, and hypertension. Upon arrival, she was noted to be hypoxic on room air and required supplemental oxygen. Physical exam showed extensive pitting edema in the lower extremities and crackles in bilateral lung fields. Chest radiograph revealed an enlarged cardiac silhouette and increased interstitial infiltrates consistent with pulmonary edema. While in the emergency departmen

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Singh, Arjun Gurmeet, and Pankaj Chaturvedi. "Areca nut and oral cancer." Oral Diseases, April 2, 2024. http://dx.doi.org/10.1111/odi.14943.

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AbstractIntroductionThe association between areca nut consumption and oral cancer has been a subject of increasing concern in global public health.Global perspectiveAreca nut, often chewed in various forms such as betel quid, is deeply rooted in cultural practices across Asia and other parts of the world. Epidemiological studies consistently reveal a significant correlation between areca nut use and the incidence of oral cancer, emphasizing the need for targeted preventive measures. The complex interplay of areca nut's bioactive compounds, particularly arecoline, with cellular processes, contr

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Osborne, Peter G., Ragavendra Rao Pasupuleti, Chien‐Hung Lee, and Vinoth Kumar Ponnusamy. "Towards a replacement therapy for stimulant betel quid dependence: A proof of concept study." Addiction Biology 29, no. 2 (2024). http://dx.doi.org/10.1111/adb.13371.

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AbstractStimulant betel quid (SBQ) containing Piper betle leaf (L), green unripe Areca catechu nut (AN) and the alkalizing agent, slaked lime, is an addictive, carcinogenic stimulant, with no pharmacotherapy, chewed by millions of people in the Asia/Pacific region. We compared the in vivo physiological profile of chewing (1) non‐stimulant P. betle leaf+AN (LAN), (2) SBQ utilizing slaked lime and (3) a novel SBQ utilizing Mg(OH)2, as an alkalizing agent, by measuring physiological parameters of intoxication and these were correlated with in vitro levels of alkaloids measured by UHPLC–MS/MS. Che

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Sari, Elizabeth Fitriana, Grace Puspita Prayogo, Yit Tao Loo, Pangzhen Zhang, Michael John McCullough, and Nicola Cirillo. "Distinct phenolic, alkaloid and antioxidant profile in betel quids from four regions of Indonesia." Scientific Reports 10, no. 1 (2020). http://dx.doi.org/10.1038/s41598-020-73337-0.

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Abstract Betel quid (BQ) is a chewing mixed package that mainly contains areca nut (AN), betel leaf (Leaf) or betel stem inflorescence (SI), and slaked lime, and is consumed with or without tobacco BQ chewing is common in South East Asia and has been strongly associated with malignant and potentially malignant diseases of the oral cavity. Alkaloids such as arecoline are often accounted for the carcinogenic potential of BQ, however the chemical composition of BQ has not been studied in detail. In the current study, we investigated the total phenolic content (TPC), antioxidant activity (by mean

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Sathasivam, Hans Prakash, Sangeetha Passu Davan, Szu May Chua, et al. "Findings from a Malaysian multicentre study on oropharyngeal squamous cell carcinoma." Infectious Agents and Cancer 18, no. 1 (2023). http://dx.doi.org/10.1186/s13027-023-00557-0.

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Abstract Background In addition to the conventional aetiologic agents of oropharyngeal squamous cell carcinoma (OPSCC) such as tobacco usage, alcohol consumption and betel quid usage, it has been established that a proportion of OPSCC are driven by persistent oncogenic human papillomavirus (HPV) infections. Currently, there is a lack of data on the burden of HPV- associated OPSCC in Asian countries including Malaysia. Methods A cross-sectional multicentre study with tissue analysis of Malaysian patients diagnosed with primary OPSCC within a five-year period, from 2015 to 2019 between 01/01/201

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Lenoci, Deborah, Elisa Moresco, Stefano Cavalieri, et al. "Oral cancer in young adults: incidence, risk factors, prognosis, and molecular biomarkers." Frontiers in Oncology 14 (September 20, 2024). http://dx.doi.org/10.3389/fonc.2024.1452909.

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Oral cavity squamous cell carcinoma (OCSCC) predominantly affects the tongue and the floor of the mouth, primarily in patients over 50 years of age. Incidence and mortality rates vary significantly worldwide, influenced by geographic areas and demographic characteristics. Epidemiological studies revealed an increase in incidence of OCSCC among young adults (YA) &lt;44 years old. This narrative review, provides updated information on the incidence, risk factors, and prognosis of YA-OCSCC using data published from 2018 to 2023 from different geographic locations. The studies indicate that th

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"Mean Lipid Profile among Patients Suffering from Oral Sub-mucous Fibrosis Reporting in a Tertiary Care Hospital of Karachi, Pakistan: A Descriptive Study." Annals of Punjab Medical College 15, no. 1 (2021): 14–18. http://dx.doi.org/10.29054/apmc/2021.1132.

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Background: Oral Submucous Fibrosis is a potent pre-malignant condition of Oral cavity, which is prevalent in South Asian countries, due to social habit of pan, gutka, areca nut and betel quid chewing, which is mostly practiced in South-East Asia. A decreased pattern of lipid profile has been observed in literature in many precancerous conditions, this study is based on observation of lipid profile pattern among Oral submucous fibrosis patients in relation with age, gender, body mass index and duration of disease. Objective: A descriptive study to determine mean lipid profile values among oral

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