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Artykuły w czasopismach na temat „Opioid habit”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 28 stycznia 2023

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Jain, Khushboo, Akansha Singh, Poonam Singh, and Sanjana Yadav. "An Improved Supervised Classification Algorithm in Healthcare Diagnostics for Predicting Opioid Habit Disorder." International Journal of Reliable and Quality E-Healthcare 11, no. 1 (January 2022): 1–16. http://dx.doi.org/10.4018/ijrqeh.297088.

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Opioid Habit Disorder (OHD), which has become a mass health epidemic, is defined as the psychological or physical dependency on opioids. This study demonstrates how supervised machine learning procedures help us investigate and examine massive data to discover the hidden patterns in any disease to deliver adapted dealing and predict the disease in any patient. This work presents a generalized model for forecasting a disease in the healthcare sector. The proposed model was investigated and tested using a reduced feature-set of the Opioid Habit Disorder (OHD) dataset collected from the National

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Wassum, K. M., I. C. Cely, N. T. Maidment, and B. W. Balleine. "Disruption of endogenous opioid activity during instrumental learning enhances habit acquisition." Neuroscience 163, no. 3 (October 2009): 770–80. http://dx.doi.org/10.1016/j.neuroscience.2009.06.071.

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Greiner, Rebecca S., Danielle Boselli, Jai N. Patel, Mariam Salib, Connie Edelen, and Declan Walsh. "Opioid Risk Screening in an Oncology Palliative Medicine Clinic." JCO Oncology Practice 16, no. 11 (November 2020): e1332-e1342. http://dx.doi.org/10.1200/op.20.00043.

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PURPOSE: Little information exists on factors that predict opioid misuse in oncology. We adopted the Screener and Opioid Assessment for Patients With Pain–Short Form (SOAPP-SF) and toxicology testing to assess for opioid misuse risk. The primary objective was to (1) identify characteristics associated with a high-risk SOAPP-SF score and noncompliant toxicology test, and (2) determine SOAPP-SF utility to predict noncompliant toxicology tests. METHODS: From July 1, 2017, to December 31, 2017, new patients completed the Edmonton Symptom Assessment Scale (ESAS), SOAPP-SF, and narcotic use agreemen

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Nnachi, Oluomachi Charity, Chinedu Obasi Akpa, Favour Ogonna Nwani, and Oghenevwogaga Obukohwo Edenya. "Pentazocine Misuse among Sickle Cell Disease Patients and The Role of Lack of Enforcement of Opioid Dispensing Regulations by Community Pharmacies: A Descriptive Observational Study." Advances in Public Health 2022 (January 30, 2022): 1–6. http://dx.doi.org/10.1155/2022/3877882.

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Introduction. Sickle cell disease (SCD) is a chronic disease characterized by debilitating bone pains which commonly necessitate the use of analgesic drugs including opioids and psychotropic substances such as pentazocine which are controlled medicines in Nigeria. Opioid misuse including dependence and addiction is an increasing trend among SCD patients, and it has serious adverse implications on their social, economic, and physical well-being. The role of lack of implementation of existent regulation on the dispensing of opioids by pharmacies has not been adequately investigated. Objective. T

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Benéitez, M. Cristina, and M. Esther Gil-Alegre. "Opioid Addiction: Social Problems Associated and Implications of Both Current and Possible Future Treatments, including Polymeric Therapeutics for Giving Up the Habit of Opioid Consumption." BioMed Research International 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/7120815.

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Background. Detoxification programmes seek to implement the most secure and compassionate ways of withdrawing from opiates so that the inevitable withdrawal symptoms and other complications are minimized. Once detoxification has been achieved, the next stage is to enable the patient to overcome his or her drug addiction by ensuring consumption is permanently and completely abandoned, only after which can the subject be regarded as fully recovered. Methods. A systematic search on the common databases of relevant papers published until 2016 inclusive. Results and Conclusion. Our study of the ava

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Li, Yingcen, Yunliang Miao, Xufang Liang, and Shan He. "Functional Characterization and Molecular Marker Development of the Proenkephalin as Biomarker of Food Addiction in Food Habit Domestication of Mandarin Fish (Siniperca Chuatsi)." Fishes 7, no. 3 (May 27, 2022): 118. http://dx.doi.org/10.3390/fishes7030118.

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Proenkephalin (PENK), as the precursor of endogenous opioid enkephalin (ENK), is widely present in the nervous system and plays an important role in animal food addiction and rewarding behavior. In our study, we intend to study the functional characterization and molecular marker development of the penk gene related to food habit domestication of mandarin fish. We found that the penk gene of mandarin fish had three types of endogenous opioid peptide sequences. Compared with other tissues, penk mRNA was highly expressed in the whole brain. Intracerebroventricular (ICV) injection of lysine or me

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Bechara, Antoine, Kent C. Berridge, Warren K. Bickel, Jose A. Morón, Sidney B. Williams, and Jeffrey S. Stein. "A Neurobehavioral Approach to Addiction: Implications for the Opioid Epidemic and the Psychology of Addiction." Psychological Science in the Public Interest 20, no. 2 (October 2019): 96–127. http://dx.doi.org/10.1177/1529100619860513.

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Two major questions about addictive behaviors need to be explained by any worthwhile neurobiological theory. First, why do people seek drugs in the first place? Second, why do some people who use drugs seem to eventually become unable to resist drug temptation and so become “addicted”? We will review the theories of addiction that address negative-reinforcement views of drug use (i.e., taking opioids to alleviate distress or withdrawal), positive-reinforcement views (i.e., taking drugs for euphoria), habit views (i.e., growth of automatic drug-use routines), incentive-sensitization views (i.e.

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Greiner, Rebecca, Danielle Boselli, Mariam Salib, and Jai Narendra Patel. "Examination of the Screener and Opioid Assessment for Patients with Pain-Short Form (SOAPP-SF) in an oncology palliative medicine clinic." Journal of Clinical Oncology 36, no. 34_suppl (December 1, 2018): 196. http://dx.doi.org/10.1200/jco.2018.36.34_suppl.196.

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196 Background: The National Comprehensive Cancer Network states opioids can be used to treat cancer pain and prescribers should identify patients at risk for opioid misuse; research in this area is limited. In the non-cancer population, SOAPP-SF is a validated tool to predict aberrant drug behavior; a score of ≥ 4 (out of 20) is considered high risk. We performed a retrospective observational study to determine the utility of the SOAPP in identifying opioid misuse in the oncology population as measured by a non-compliant toxicology screen. Methods: Consecutive consults seen during a 6-month p

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Halepas, Steven, Cameron Christiansen, Alia Koch, Shahid R. Aziz, David M. Shafer, and Elie M. Ferneini. "Opioid-Prescribing Patterns in Connecticut and New Jersey Following Third Molar Extractions." Anesthesia Progress 69, no. 4 (December 1, 2022): 9–14. http://dx.doi.org/10.2344/anpr-69-02-12.

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Objective In recent years, opioid misuse has resulted in much scrutiny on providers' prescribing habits. The purpose of this study was to analyze prescribing habits in the context of third molar extractions as a model for promoting better postsurgical pain management. Methods This was a cross-sectional survey of oral maxillofacial surgeons in Connecticut and New Jersey. A total of 291 practitioners were contacted to complete an online survey using Qualtrics Research Services to determine prescribing habits following third molar extractions. Results The most common approach for postoperative an

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Schinas, MSc, Anna, Shein Nanji, BSc, Kira Vorobej, MSc, Catherine Mills, MSc, Dawn Govier, BSc, and Beatrice Setnik, PhD. "Key characteristics and habits of the recreational opioid user." Journal of Opioid Management 15, no. 6 (November 1, 2019): 507–20. http://dx.doi.org/10.5055/jom.2019.0542.

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Objective: To identify key characteristics and habits of recreational opioid users.Design: The data were compiled from volunteers who participated in clinical studies at a contract research organization in Toronto, Ontario, Canada.Interventions: Data were collected from 5,018 male and female recreational opioid users via telephone and face-to-face screening interviews. Five recreational opioid users participated in a live interview broadcast on the internet.Main outcome measures: Demographic data, recreational drug use history, routes of recreational drug administration, alcohol use, and smoki

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Jarlbaek, Lene. "Opioid prescribing habits differ between Denmark, Sweden and Norway – and they change over time." Scandinavian Journal of Pain 19, no. 3 (July 26, 2019): 491–99. http://dx.doi.org/10.1515/sjpain-2018-0342.

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Abstract Background and aims The medical use of opioids in different countries is often subject to public concern and debate, frequently based on rough figures from prescription databases made for registration of consumption. However, public access to some of these databases allow for further exploration of the prescription data, which can be processed to increase knowledge and insight into national opioid prescribing-behavior. Denmark, Sweden and Norway are considered closely related with regard to health care and culture. So, this study aims to provide a more detailed picture of opioid presc

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Morgan, Jessica Kelley, Steven K. Walther, and Marian E. Lane. "Evaluation of a Mobile Application to Decrease Opioid Misuse and Habit-Forming Behaviors Following Prescription: Preliminary Results and Future Directions." Psychology 10, no. 15 (2019): 2019–25. http://dx.doi.org/10.4236/psych.2019.1015129.

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Bril, Silviu, Yoav Shoham, and Jeremy Marcus. "The ‘Mystery’ of Opioid-Induced Diarrhea." Pain Research and Management 16, no. 3 (2011): 197–99. http://dx.doi.org/10.1155/2011/309685.

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Bowel dysfunction, mainly constipation, is a well-known and anticipated side effect of opioids. The physician prescribing an opioid frequently confronts the challenge of preventing and treating bowel dysfunction. Different strategies have emerged for managing opioid-induced constipation. These strategies include physical activity, maintaining adequate fluid intake, adhering to regular daily bowel habits, using laxatives and other anticonstipation medications and, recently, using a peripheral opioid antagonist, either as a separate drug or in the form of an opioid agonist-antagonist combination

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Thibodeaux, Anne Marie, Keith Foster, Jessica W. Skelley, and Marion Sims. "Opioid Prescribing Habits in a Family Medicine Residency Program for the Management of Non-Cancer Pain." INNOVATIONS in pharmacy 10, no. 2 (May 20, 2019): 10. http://dx.doi.org/10.24926/iip.v10i2.1149.

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Objectives: 1. List components of the 2016 CDC Guideline for Prescribing Opioids for Chronic Pain, 2. Describe the prescribing habits of medical residents and attending physicians within a family medicine residency program, 3. Discuss the direction of future research Methods: A report was generated for all patients with opioids listed as a medication at Christ Health Center family medicine clinic from July 2016 to June 2017. A total of 153 patients were identified with prescriptions written for chronic non-cancer pain indications. Clinical management via a retrospective chart review was

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Hek, Karin, Tim Boogaerts, Robert A. Verheij, Hans De Loof, Liset van Dijk, Alexander L. N. van Nuijs, Willemijn M. Meijer, and Hilde Philips. "Opioid prescribing in out-of-hours primary care in Flanders and the Netherlands: A retrospective cross-sectional study." PLOS ONE 17, no. 4 (April 7, 2022): e0265283. http://dx.doi.org/10.1371/journal.pone.0265283.

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Background Increased opioid prescribing has raised concern, as the benefits of pain relief not always outweigh the risks. Acute and chronic pain is often treated in a primary care out-of-hours (OOH) setting. This setting may be a driver of opioid use but the extent to which opioids are prescribed OOH is unknown. We aimed to investigate weak and strong opioid prescribing at OOH primary care services (PCS) in Flanders (Northern, Dutch-speaking part of Belgium) and the Netherlands between 2015 and 2019. Methods We performed a retrospective cross sectional study using data from routine electronic

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Lewis, Rachel E., Bethany R. Sappington, Andrew J. Ward, Robert E. Heidel, James M. Lewis, and James M. Mcloughlin. "Optimal Pain Control after Outpatient Surgery for Cutaneous Malignancies." American Surgeon 85, no. 9 (September 2019): 956–60. http://dx.doi.org/10.1177/000313481908500935.

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Postoperative pain managed with opioids has contributed to the opioid crisis through over-prescribing practices. We assessed opioid-prescribing habits and their use by patients undergoing surgery for cutaneous malignancies. An Institutional Review Board–approved retrospective analysis was conducted for patients who underwent skin cancer resection between January 2018 and June 2018. Data were collected from the electronic medical record, and opioid-related data were collected from patient interviews and state registries. There were 120 study participants (42 females and 78 males) with a median

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Ormsby, MD, Andrew, and Caitlin Dietsche, MD. "The effect of the COVID-19 pandemic on opioid prescribing for patients with pleuritic pain." Journal of Opioid Management 18, no. 6 (November 1, 2022): 529–35. http://dx.doi.org/10.5055/jom.2022.0748.

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Objective: We sought to understand opioid prescribing for COVID-19 positive and negative patients with pleuritic pain during the first wave of the pandemic. We hypothesized that patients without COVID-19 would be prescribed opioids more frequently intrapandemic compared to prepandemic and postulated that COVID-19 patients would be prescribed opioids more frequently and at greater quantity than their peers.Design: A retrospective observational analysis of electronic health record data.Setting: A quaternary academic hospital from February through April 2020.Participants: A total of 1,400 of 3,16

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Nadeau, Robert, Kristopher Hasstedt, Ashley Brooke Sunstrum, Chad Wagner, and Harold Tu. "Addressing the Opioid Epidemic: Impact of Opioid Prescribing Protocol at the University of Minnesota School of Dentistry." Craniomaxillofacial Trauma & Reconstruction 11, no. 2 (June 2018): 104–10. http://dx.doi.org/10.1055/s-0038-1649498.

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Prescription opioid medications continue to be abused on an epidemic level and have been shown to be a “gateway” drug to heroin abuse. Individuals experimenting with opioids commonly fall in the 10- to 19-year age range in which dentists are the highest prescribers. To reduce the number of excess opioids, the Department of Oral and Maxillofacial Surgery, University of Minnesota, developed and implemented an evidence-based opioid prescribing policy. Data were collected via electronic health record for the previous year and compared with the year following the protocol implementation. The result

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El-Amin, Nadirah, Paul Nietert, and Julie Kanter. "Opioid Prescribing Habits in Sickle Cell Disease: An International Survey of Providers." Blood 132, Supplement 1 (November 29, 2018): 2371. http://dx.doi.org/10.1182/blood-2018-99-117206.

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Abstract Introduction: Vaso-occlusive pain crisis (VOC) are the hallmark of sickle cell disease (SCD) and the primary reason for which affected individuals seek acute care (Boussard et al JAMA, 2010). Both national and international guidelines recommend aggressive IV opioids, intravenous fluids and anti-inflammatory therapy as the mainstay of treatment for acute SCD pain. In an effort to avoid acute care for VOC, many pain crises are managed at home with oral agents, including anti-inflammatory and opioid medications. However, there are no current guidelines on the use and type of medications

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Ho, Edward, Matthew Doherty, Robert Thomas, John Attia, Christopher Oldmeadow, and Matthew Clapham. "Prescription of opioids to post-operative orthopaedic patients at time of discharge from hospital: a prospective observational study." Scandinavian Journal of Pain 18, no. 2 (April 25, 2018): 253–59. http://dx.doi.org/10.1515/sjpain-2017-0149.

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Abstract Background and aims: Excessive opioid prescribing can lead to adverse consequences including stockpiling, misuse, dependency, diversion and mortality. Increased prescriptions to post-operative inpatients as part of their discharge planning may be a significant contributor. Primary aims included comparing the amount of opioids prescribed, consumed, left unused and their relationship with pain and functionality. Methods: A total of 132 consecutive patients who underwent elective orthopaedic surgery were prospectively audited. Daily oral morphine equivalent (DME) of opioids prescribed wa

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Sadowski, MD, FHM, Richard, Emily Hillaker, DO, Michael Chavarria, MD, Fareea Khaliq, MD, and Adam Schwark, MD. "A retrospective analysis of the impact of Michigan's opioid prescribing legislation on discharge opioid prescribing at a single institution." Journal of Opioid Management 18, no. 5 (September 1, 2022): 467–74. http://dx.doi.org/10.5055/jom.2022.0740.

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This study sought to determine if there were any changes in opioid prescribing habits of providers at a single institution after the implementation of legislation to increase opioid prescribing regulations. Our study demonstrated a 39.5 percent decrease in overall morphine milligram equivalent (MME) prescribed the year after the laws took effect when compared with the year prior. It is clear that these laws have been effective in decreasing the number of opioids prescribed at discharge from Mercy Health Grand Rapids.Introduction: Opioid use disorder has become an epidemic with approximately 13

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Thompson, Matthew M., Lucas Popp, Michael J. Foster, Hassan Malik, and R. Frank Henn. "Opioid Prescribing Habits for Common Arthroscopic Procedures in Opioid Naïve Patients." Orthopaedic Journal of Sports Medicine 9, no. 5 (May 1, 2021): 232596712110092. http://dx.doi.org/10.1177/23259671211009263.

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Background: With the opioid epidemic and the increasing number of opioid-related deaths, there is growing awareness in the medical community regarding the dangers of opioid overprescription. As a result, there is a willingness among physicians to abandon old norms and adopt new data-driven prescribing practices. Purpose: To demonstrate patient-reported consumption data of opioid medications after anterior cruciate ligament (ACL) reconstructions (ACLRs), knee arthroscopies, and rotator cuff repairs to provide data-driven guidelines for prescribing opioids after these procedures. Study Design: C

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Rivera, Alicia, Diana Suárez-Boomgaard, Cristina Miguelez, Alejandra Valderrama-Carvajal, Jérôme Baufreton, Kirill Shumilov, Anne Taupignon, Belén Gago, and M. Ángeles Real. "Dopamine D4 Receptor Is a Regulator of Morphine-Induced Plasticity in the Rat Dorsal Striatum." Cells 11, no. 1 (December 23, 2021): 31. http://dx.doi.org/10.3390/cells11010031.

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Long-term exposition to morphine elicits structural and synaptic plasticity in reward-related regions of the brain, playing a critical role in addiction. However, morphine-induced neuroadaptations in the dorsal striatum have been poorly studied despite its key function in drug-related habit learning. Here, we show that prolonged treatment with morphine triggered the retraction of the dendritic arbor and the loss of dendritic spines in the dorsal striatal projection neurons (MSNs). In an attempt to extend previous findings, we also explored whether the dopamine D4 receptor (D4R) could modulate

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Ramadan, Majed, Yahya Alnashri, Amjad Ilyas, Omar Batouk, Khalid A. Alsheikh, Laila Alhelabi, and Suliman Abdulah Alnashri. "Assessment of opioid administration patterns following lower extremity fracture among opioid-naïve inpatients: retrospective multicenter cohort study." Annals of Saudi Medicine 42, no. 6 (November 2022): 366–76. http://dx.doi.org/10.5144/0256-4947.2022.366.

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BACKGROUND: Prescribing habits during admission have largely contributed to the opioid epidemic. Orthopedic surgeons represent the third-highest opioid-prescribing specialty. Since more than half of body fractures in Saudi Arabia have been lower extremity fractures, it is imperative to understand opioid administration patterns and correlates among opioid-naïve inpatients. OBJECTIVES: Assess opioid administration patterns and correlates among opioid-naïve inpatients with lower extremity fractures. DESIGN AND SETTINGS: Retrospective cohort PATIENTS AND METHODS: Opioid naïve individuals aged 18 t

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Alexander, John C. "Evaluation of Opioid Prescribing Habits Based on Analysis of a State Prescription Drug Monitoring Program." Pain Physician 5, no. 22;5 (September 11, 2019): E425—E433. http://dx.doi.org/10.36076/ppj/2019.22.e425.

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Background: The current opioid epidemic is perhaps the greatest public health crisis in the United States. Although multiple factors led to the rise of this epidemic, it is without question associated with the rise in opioid prescribing. Objectives: Better understanding of the opioid prescribing may provide insights into populationlevel trends contributing to this epidemic, and opportunities to decrease the magnitude of opioid overdose-related death. Therefore we assessed trends in opioid prescribing habits based on analysis of the Texas Prescription Drug Monitoring Program (PDMP) and geograph

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Lovecchio, Francis, Ajay Premkumar, Tyler Uppstrom, Jeffrey Stepan, Brittany Ammerman, Moira McCarthy, Beth Shubin Stein, et al. "Opioid Consumption After Arthroscopic Meniscal Procedures and Anterior Cruciate Ligament Reconstruction." Orthopaedic Journal of Sports Medicine 8, no. 4 (April 1, 2020): 232596712091354. http://dx.doi.org/10.1177/2325967120913549.

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Background: Procedure-specific opioid-prescribing guidelines have the potential to decrease the number of unused pills in the home without compromising patient satisfaction. However, there is a paucity of data on the minimum necessary quantity to prescribe for outpatient orthopaedic surgeries. Purpose: To prospectively record daily opioid use and pain levels after arthroscopic meniscal procedures and anterior cruciate ligament reconstruction (ACLR) at a single institution. Study Design: Case series; Level of evidence, 4. Methods: A total of 95 adult patients who underwent primary arthroscopic

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Mandava, Nikhil, Demetris Delos, Katherine Vadasdi, R. Greene, Marc Kowalsky, Francis Alberta, Paul Sethi, and Parth Kamdar. "An Evidence Driven Opioid Prescribing Guideline following Knee Arthroscopy and Anterior Cruciate Ligament Reconstruction." Orthopaedic Journal of Sports Medicine 8, no. 7_suppl6 (July 1, 2020): 2325967120S0039. http://dx.doi.org/10.1177/2325967120s00393.

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Objectives: Opioid prescriptions following knee arthroscopy vary substantially, ranging from 15 to 60 opioid pills.[1-3] Expert panel guidelines recommend up to 30 pills for knee arthroscopy and 60 pills for anterior cruciate ligament reconstruction (ACLR) using an autograft; however, these recommendations are based on consensus rather than evidence.[4] Currently, orthopaedic surgeons do not possess any evidence driven guidelines for opioid prescriptions following knee arthroscopy or ACLR. The purpose of this study was to record patients’ postoperative opioid requirement to develop evidence dr

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Katz, Andrew P., Carly Misztal, Michael K. Ghiam, and Michael E. Hoffer. "Changes in Single-Specialty Postoperative Opioid Prescribing Patterns in Response to Legislation: Single-Institution Analysis Over Time." Otolaryngology–Head and Neck Surgery 164, no. 4 (February 2, 2021): 774–80. http://dx.doi.org/10.1177/0194599820986577.

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Objectives To determine changes in the prescriptions of postoperative opioids in response to Florida state legislation restricting the number of days for which these medications could be prescribed to 3 days in most circumstances or 7 days at provider discretion. Study Design A retrospective review was performed for all patients undergoing 7 common outpatient otolaryngology surgical procedures. Setting Single-institution academic center in Florida. Methods Query of the state’s online prescription drug monitoring program was used to compare prescription habits 3 months before and after the law

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Trivedi, Sunny, Kevin Shea, Whitney Chadwick, Shabnam Gaskari, Ellen Wang, and Thomas Caruso. "A QUALITY IMPROVEMENT PROJECT TO REDUCE THE USE OF COMBINATION OPIOID/ACETAMINOPHEN MEDICATIONS WITHIN A LARGE HEALTH SYSTEM." Orthopaedic Journal of Sports Medicine 8, no. 4_suppl3 (April 1, 2020): 2325967120S0025. http://dx.doi.org/10.1177/2325967120s00258.

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Background: Combination analgesics are among the most commonly prescribed pain medications in pediatric orthopedic patients. However, combined analgesics do not allow for individual medication titration, which can increase the risk of opioid misuse and hepatoxicity from acetaminophen. Increasingly, the risks of combined analgesics associated with opioid misuse and hepatotoxicity are recognized by the FDA and other organizations. Given these risks, consideration should be made for independent administration of acetaminophen and opioids. Hypothesis/Purpose: The primary aim was to alter the presc

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Siva, Shivi, Chung Sang Tse, Nayantara Coelho-Prabhu, and Rajeev Jain. "AMERICAN GASTROENTEROLOGICAL ASSOCIATION’S QUALITY LEADERSHIP COUNCIL’S PRACTICE WORK GROUP: A NATIONWIDE INITIATIVE TO REDUCE THE USE OF PRESCRIPTION OPIOID AMONG PATIENTS WITH INFLAMMATORY BOWEL DISEASE AT A LOCAL LEVEL." Inflammatory Bowel Diseases 27, Supplement_1 (January 1, 2021): S48. http://dx.doi.org/10.1093/ibd/izaa347.114.

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Abstract Background and aims The use of opioids among patients with inflammatory bowel disease (IBD) in the United States is increasing and it is associated with higher mortality, re-admissions, healthcare utilization, and disability. The American Gastroenterological Association’s (AGA) Quality Leadership Council’s practice workgroup developed educational materials to educate and modify narcotic prescribing habits of providers treating IBD and change the attitudes and expectations of patients who require analgesics. Methods Council members participated in two 1-hour virtual planning meetings t

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Xia, Yixue, and Patrice Forget. "Opioid and gabapentinoid prescriptions in England from 2015 to 2020." PLOS ONE 17, no. 11 (November 28, 2022): e0276867. http://dx.doi.org/10.1371/journal.pone.0276867.

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Purpose Concerns gradually arose about misuse of gabapentinoids (gabapentin and pregabalin), especially when used in combination with opioids. Because it can be a driver of usage, trends in prescribing habits may be interesting to analyse. The aim of this study is to examine the evolution of prescriptions of opioids and gabapentinoids in England from 2015 to 2020 at a regional level. Methods This study included data from April 2015 to February 2020, focusing on prescribing data, extracted the OpenPrescribing database. We described the evolution of the prescriptions of opioids and gabapentinoid

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Arshonsky, Josh, Noa Krawczyk, Amanda M. Bunting, David Frank, Samuel R. Friedman, and Marie A. Bragg. "Informal Coping Strategies Among People Who Use Opioids During COVID-19: Thematic Analysis of Reddit Forums." JMIR Formative Research 6, no. 3 (March 3, 2022): e32871. http://dx.doi.org/10.2196/32871.

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Background The COVID-19 pandemic has transformed how people seeking to reduce opioid use access treatment services and navigate efforts to abstain from using opioids. Social distancing policies have drastically reduced access to many forms of social support, but they may have also upended some perceived barriers to reducing or abstaining from opioid use. Objective This qualitative study aims to identify informal coping strategies for reducing and abstaining from opioid use among Reddit users who have posted in opioid-related subreddits at the beginning of the COVID-19 pandemic. Methods We extr

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Diasso, Pernille D. K., Per Sjøgren, Jette Højsted, Susanne D. Nielsen, Katharina M. Main, and Geana P. Kurita. "Patient reported outcomes and neuropsychological testing in patients with chronic non-cancer pain in long-term opioid therapy: a pilot study." Scandinavian Journal of Pain 19, no. 3 (July 26, 2019): 533–43. http://dx.doi.org/10.1515/sjpain-2019-0007.

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Abstract Background and aims Opioid consumption has increased dramatically in patients with chronic non-cancer pain (CNCP), but long-term consequences are still unclear. The aim of this study is to investigate the effects of long-term opioid treatment on pain, cognition, mood, sleep and quality of life in CNCP patients. Methods In this cross-sectional pilot study, two groups of patients with CNCP treated in a multidisciplinary pain center were selected: (1) opioid group: ≥30 mg morphine equivalent/day for >4 weeks, and (2) control group: no opioid consumption for >4 weeks. Socio-demograp

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Stowe, G. Neil, Ryan B. Paulsen, Virginia A. Hill, and Michael I. Schaffer. "A Retrospective Analysis of Selected Opioids in Hair of Workplace Drug Testing Subjects." Journal of Analytical Toxicology 43, no. 7 (April 22, 2019): 553–63. http://dx.doi.org/10.1093/jat/bkz015.

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Abstract Opioids, both naturally occurring and semisynthetic, are effective pain management medications, but also possess the potential for abuse. Analyses of over 37,000 head and body hair samples containing codeine, morphine, hydrocodone, hydromorphone, oxycodone or oxymorphone provide a view of use habits of workplace-testing subjects that cannot be obtained from fluid matrices results. Testing was performed using FDA cleared immunoassays using either 2 ng morphine or oxycodone per 10 mg hair as calibrators. Non-negative screening samples were washed with an extended aqueous wash procedure

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VanIderstine, Carter, Michael Dunbar, and Emily Johnston. "Opioid Prescribing Habits of Orthopedic Surgeons Following Total Hip Arthroplasty and Total Knee Arthroplasty: A Pilot Study." Canadian Journal of Hospital Pharmacy 75, no. 4 (October 3, 2022): 335–39. http://dx.doi.org/10.4212/cjhp.3282.

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Background: Adequate pain management is important in patients’ recovery from total hip arthroplasty (THA) and total knee arthroplasty (TKA). Objective: To determine whether risk factors for prolonged opioid use are considered when discharge prescriptions for postoperative pain are written following THA and TKA. Methods: Opioid prescriptions written between June 14 and July 9, 2021, for patients who underwent THA or TKA were analyzed. Data were also collected on the patients’ age, sex, type of surgery, type of anesthesia (regional or general), preoperative use of opioids, and preoperative use o

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Lee, Jonathan, Ghadi Ghanem, Soheil Saadat, Justin Yanuck, Brent Yeung, Bharath Chakravarthy, Ariana Nelson, and Shalini Shah. "Positive Toxicology Results Are Not Associated with Emergency Physicians’ Opioid Prescribing Behavior." Western Journal of Emergency Medicine 22, no. 5 (August 30, 2021): 1067–75. http://dx.doi.org/10.5811/westjem.2021.5.52378.

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Introduction: Given the general lack of literature on opioid and naloxone prescribing guidelines for patients with substance use disorder, we aimed to explore how a physician’s behavior and prescribing habits are altered by knowledge of the patient’s concomitant use of psychotropic compounds as evident on urine and serum toxicology screens. Methods: We conducted a retrospective chart review study at a tertiary, academic, Level I trauma center between November 2017–October 2018 that included 358 patients who were discharged from the emergency department (ED) with a diagnosis of fracture, disloc

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Sheldon, Rowan R., Jessica B. Weiss, Woo S. Do, Dominic M. Forte, Preston L. Carter, Matthew J. Eckert, and Vance Y. Sohn. "Stemming the Tide of Opioid Addiction—Dramatic Reductions in Postoperative Opioid Requirements Through Preoperative Education and a Standardized Analgesic Regimen." Military Medicine 185, no. 3-4 (October 17, 2019): 436–43. http://dx.doi.org/10.1093/milmed/usz279.

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Abstract Introduction Surgery is a known gateway to opioid use that may result in long-term morbidity. Given the paucity of evidence regarding the appropriate amount of postoperative opioid analgesia and variable prescribing education, we investigated prescribing habits before and after institution of a multimodal postoperative pain management protocol. Materials and Methods Laparoscopic appendectomies, laparoscopic cholecystectomies, inguinal hernia repairs, and umbilical hernia repairs performed at a tertiary military medical center from 01 October 2016 until 30 September 2017 were examined.

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Drewes, Asbjørn M., Pia Munkholm, Magnus Simrén, Harald Breivik, Ulf E. Kongsgaard, Jan G. Hatlebakk, Lars Agreus, Maria Friedrichsen, and Lona L. Christrup. "Definition, diagnosis and treatment strategies for opioid-induced bowel dysfunction–Recommendations of the Nordic Working Group." Scandinavian Journal of Pain 11, no. 1 (April 1, 2016): 111–22. http://dx.doi.org/10.1016/j.sjpain.2015.12.005.

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AbstractBackground and aimsOpioid-induced bowel dysfunction (OIBD) is an increasing problem due to the common use of opioids for pain worldwide. It manifests with different symptoms, such as dry mouth, gastro-oesophageal reflux, vomiting, bloating, abdominal pain, anorexia, hard stools, constipation and incomplete evacuation. Opioid-induced constipation (OIC) is one of its many symptoms and probably the most prevalent. The current review describes the pathophysiology, clinical implications and treatment of OIBD.MethodsThe Nordic Working Group was formed to provide input for Scandinavian specia

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Kamdar, Parth, Christopher Antonacci, Katherine Vadasdi, R. Greene, Francis Alberta, Paul Sethi, and Nicole Liddy. "Poster 223: Evidence-Based Opioid Prescribing Guidelines Following Anterior Cruciate Ligament Reconstruction (ACLR)." Orthopaedic Journal of Sports Medicine 10, no. 7_suppl5 (July 1, 2022): 2325967121S0078. http://dx.doi.org/10.1177/2325967121s00784.

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Objectives: Opioid prescriptions following anterior cruciate ligament reconstruction (ACLR) vary substantially.1-3 Expert panel guidelines recommend up to 50 pills for ACLR with many surgeons refilling 40 or more tablets.1,3 The CDC warns that a five-day supply is sufficient to develop opiate dependence.4 Current recommendations are based on consensus rather than evidence and place a vulnerable population at risk for opiate misuse.2,3 Orthopaedic surgeons do not possess evidence driven regimens for opioid prescriptions following ACLR.5,6 The purpose of this study was to develop evidence-based

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Diehl, Beau J. "Compensatory Eating Behaviors, Alcohol Consumption and Opioid Use in a Clinical Sample." International Journal of Social Science Studies 5, no. 5 (April 24, 2017): 87. http://dx.doi.org/10.11114/ijsss.v5i5.2376.

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Objectives: To estimate the prevalence of compensatory eating behaviors in relation to alcohol consumption in a clinical sample, to assess the moderating capabilities of opioid use in relation to alcohol use and compensatory behaviors, and to examine the predictive capabilities of gender-specific binge drinking in relation to compensatory behaviors.Methods: The Compensatory Eating Behaviors in Relation to Alcohol Consumption Scale (CEBRACS), an opioid use survey, and the Alcohol Use Disorders Identification Test (AUDIT) were administered to residents at an addiction treatment facility (n = 77)

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Gupta, Akash, Kanupriya Kumar, Matthew M. Roberts, Austin E. Sanders, Mackenzie T. Jones, David S. Levine, Martin J. O’Malley, et al. "Pain Management After Outpatient Foot and Ankle Surgery." Foot & Ankle International 39, no. 2 (October 27, 2017): 149–54. http://dx.doi.org/10.1177/1071100717738495.

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Background: The number of opioids prescribed and used has increased precipitously over the past 2 decades for a number of reasons and has led to increases in long-term dependency, opioid-related deaths, and diversion. Most studies examining the role of prescribing habits have investigated nonoperative providers, although there is some literature describing perioperative opioid prescription and use. There are no studies looking at the number of pills consumed after outpatient foot and ankle surgeries, nor are there guidelines for how many pills providers should prescribe. The purpose of this st

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Priano, James, Brian Faley, Gabrielle Procopio, Kevin Hewitt, and Joseph Feldman. "Adjunct Analgesic Use for Acute Pain in the Emergency Department." Hospital Pharmacy 52, no. 2 (February 2017): 138–43. http://dx.doi.org/10.1310/hpj5202-138.

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Purpose Multimodal analgesia is common practice in the postoperative setting, but the utility of adjunctive analgesia in the emergency department (ED) is less understood. The primary objective of this study was to analyze ED prescriber ordering habits for adjunct nonopioid pain medication for opioid-naïve patients who require intravenous (IV) morphine or hydromorphone for acute pain. Secondary objectives were to assess initial and total opioid consumption in morphine equivalent units (MEU), pain scores, and ED length of stay (LOS) between groups. Methods A retrospective chart review of adult p

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Ziolkowski, Natalia, Josephine D’Abbondanza, Sarah Rehou, and Shahriar Shahrohki. "110 Pain Medication Prescription Patterns and the American Burn Association 2020 Guidelines on the Management of Acute Pain in the Adult Burn Patient." Journal of Burn Care & Research 42, Supplement_1 (April 1, 2021): S74. http://dx.doi.org/10.1093/jbcr/irab032.114.

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Abstract Introduction In September 2020, the American Burn Association released new pain guidelines following a rigorous literature review and input from experts. These guidelines were last updated 14 years ago and represent a multitude of changes including increased importance for non-opioid pain medication use and non-pharmacologic adjuncts given the current opioid crisis. Specifically, the main recommendations were to use opioid medication sparingly and always with adjuncts; acetaminophen utilized in all patients; NSAID use depending on baseline comorbidities and kidney function; neuropathi

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Ash, Nathan, Jedediah Tuten, Wayne Bohenek, and Brian Latham. "A comprehensive approach to addressing the opioid epidemic in a large health system." American Journal of Health-System Pharmacy 78, no. 4 (January 20, 2021): 320–26. http://dx.doi.org/10.1093/ajhp/zxaa388.

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Abstract Purpose To describe the implementation of a comprehensive program to address the opioid epidemic in a large health system and to assess the effect of the program on opioid prescribing. Summary Mercy Health is a nonprofit, Catholic health system that employs over 1,400 providers and operates 23 hospitals in Ohio and Kentucky, 2 states that have experienced large numbers of overdoses. As a good community partner, the health system developed a comprehensive plan to address the opioid crisis. A system-wide Opioid Steering Committee was established to implement and manage the program. The

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Suleiman, Zakari A., Kolawole W. Wahab, and Israel K. Kolawole. "Opioid prescribing habits of physicians in Kwara State, Nigeria." Ghana Medical Journal 50, no. 2 (July 18, 2016): 63. http://dx.doi.org/10.4314/gmj.v50i2.2.

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Sceats, Lindsay A., Nagehan Ayakta, Sylvia Bereknyei Merrell, and Cindy Kin. "Drivers, Beliefs, and Barriers Surrounding Surgical Opioid Prescribing: A Qualitative Study of Surgeons’ Opioid Prescribing Habits." Journal of Surgical Research 247 (March 2020): 86–94. http://dx.doi.org/10.1016/j.jss.2019.10.039.

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Habbouche, Joe A., Jay S. Lee, Caitlin Khalsa, Ryan Howard, Hsou Mei Hu, Michael J. Englesbe, Chad Brummett, and Jennifer F. Waljee. "Effect of Opioid Schedule Change on Prescribing Habits of Surgeons." Journal of the American College of Surgeons 225, no. 4 (October 2017): S82. http://dx.doi.org/10.1016/j.jamcollsurg.2017.07.175.

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Srinivasan, Shriya, Khalil B. Ramadi, Andrea Ippolito, and Rifat Atun. "Democratizing innovation through grass-roots entrepreneurship: lessons from efforts to address the opioid epidemic in the United States." BMJ Global Health 4, no. 6 (December 2019): e002079. http://dx.doi.org/10.1136/bmjgh-2019-002079.

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The nationwide opioid epidemic has substantially impacted economically-depressed regions in the USA. Eastern Appalachia has some of the lowest socioeconomic indicators in the USA and has suffered the highest rate of opioid-related fatality in 2016. Despite devoting considerable federal and state resources towards public health initiatives, the region continued to experience one of the highest death rates and sought alternative approaches to address the opioid crisis. Here, we describe a community-based co-creation initiative that convened diverse sectors and utilised design thinking principles

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Yahya, Ayesha, Christian C. Hall, Andrew Wilhelm, and Chelsea Bush. "A Prospective Evaluation of Opioid Utilization Following Ankle Fracture Surgery." Foot & Ankle Orthopaedics 7, no. 4 (October 2022): 2473011421S0101. http://dx.doi.org/10.1177/2473011421s01010.

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Category: Trauma; Ankle Introduction/Purpose: There has been significant scrutiny of physicians' opioid prescribing patterns for both operative and non- operative patients. Orthopaedic surgeons are the third highest group of opioid prescribers among physicians in the United States. The wide scope of orthopaedic procedures lends to the variability and difficulty in setting forth prescribing guidelines. Recent orthopedic literature has highlighted that orthopaedic surgeons are prescribing excess narcotic medication than is needed in common orthopaedic procedures. Ankle fractures make up about 9%

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Aulet, Ricardo Mario, Vanessa Trieu, Gary P. Landrigan, and Donna J. Millay. "Changes in Opioid Prescribing Habits for Patients Undergoing Rhinoplasty and Septoplasty." JAMA Facial Plastic Surgery 21, no. 6 (November 1, 2019): 487–90. http://dx.doi.org/10.1001/jamafacial.2019.0937.

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