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Gotowe bibliografie tematyczne / Oral submucous fibrosis (OSF); precancerous disorder

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Gotowa bibliografia na temat „Oral submucous fibrosis (OSF); precancerous disorder”

Autor: Grafiati

Data publikacji: 2 czerwca 2025

Data aktualizacji: 31 lipca 2025

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Artykuły w czasopismach na temat "Oral submucous fibrosis (OSF); precancerous disorder"

1

Shih, Yin-Hwa, Tong-Hong Wang, Tzong-Ming Shieh, and Yu-Hsin Tseng. "Oral Submucous Fibrosis: A Review on Etiopathogenesis, Diagnosis, and Therapy." International Journal of Molecular Sciences 20, no. 12 (2019): 2940. http://dx.doi.org/10.3390/ijms20122940.

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Oral submucous fibrosis (OSF) is characterized by abnormal collagen deposition. It is a precancerous disorder and transforms into a malignant tumor in 1.5–15% of all cases. Symptoms include submucous fibrosis, ulceration, xerostomia, a burning sensation, and restricted mouth opening. All of these greatly interfere with patient quality of life. The present review introduces OSF from a molecular perspective and summarizes what is known about its underlying mechanisms, diagnostic biomarkers, and therapeutic interventions. In addition to the aggressive treatment of OSF, its prevention is also impo

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Soham, Kulkarni Sachin Jadhav Sahil Shaikh* Suraj Gholap. "A Review on Screening Model for Submucosa Fibrosis." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3445–56. https://doi.org/10.5281/zenodo.15475252.

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Oral submucous fibrosis (OSF) is characterized by abnormal collagen deposition. It is a precancerous disorder and transforms into a malignant tumor in 1.5–15% of all cases. Symptoms include submucous fibrosis, ulceration, xerostomia, a burning sensation, and restricted mouth opening. All of these greatly interfere with patient quality of life. The present review introduces OSF from a molecular perspective and summarizes what is known about its underlying mechanisms, and therapeutic interventions. In addition to the aggressive treatment of OSF, its prevention is also important. Oral submu

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You, Jie-Ru, Ya-Ting Chen, Chia-Yu Hsieh, et al. "Exploring Possible Diagnostic Precancerous Biomarkers for Oral Submucous Fibrosis: A Narrative Review." Cancers 15, no. 19 (2023): 4812. http://dx.doi.org/10.3390/cancers15194812.

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Oral submucous fibrosis (OSF) stands as a progressive oral ailment, designated as a potentially malignant disorder. OSF has gained widespread recognition as a significant precursor to malignant transformation. In the pursuit of dependable, straightforward, and non-invasive diagnostic measures for the early detection of oral malignant progression, research has delved into potential diagnostic biomarkers of OSF. This comprehensive review delves into current investigations that explore the correlation between various biomarkers and OSF. The molecular biomarkers of OSF are categorized based on cyt

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Yu, Chuan-Hang, Chih-Yuan Fang, Cheng-Chia Yu, et al. "LINC00312/YBX1 Axis Regulates Myofibroblast Activities in Oral Submucous Fibrosis." International Journal of Molecular Sciences 21, no. 8 (2020): 2979. http://dx.doi.org/10.3390/ijms21082979.

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Oral submucous fibrosis (OSF) has been recognized as a precancerous disorder in the oral cavity. Great effort has been made to inhibit the malignant progression of OSF over the past decades, but the cure of this fibrosis disease has not been discovered. In the present study, we found that a long noncoding RNA, LINC00312, was upregulated in OSF tissues, and positively associated with several fibrosis factors, such as α-SMA, type I collagen, and fibronectin. As such, we sought to investigate the role of LINC00312 in OSF progression and identify its interacting factor that mediated oral fibrogene

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Yu, Cheng-Chia, Yi-Wen Liao, Pei-Ling Hsieh, and Yu-Chao Chang. "Targeting lncRNA H19/miR-29b/COL1A1 Axis Impedes Myofibroblast Activities of Precancerous Oral Submucous Fibrosis." International Journal of Molecular Sciences 22, no. 4 (2021): 2216. http://dx.doi.org/10.3390/ijms22042216.

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Oral submucous fibrosis (OSF) is known as a potentially malignant disorder, which may result from chemical irritation due to areca nuts (such as arecoline). Emerging evidence suggests that fibrogenesis and carcinogenesis are regulated by the interaction of long noncoding RNAs (lncRNAs) and microRNAs. Among these regulators, profibrotic lncRNA H19 has been found to be overexpressed in several fibrosis diseases. Here, we examined the expression of H19 in OSF specimens and its functional role in fibrotic buccal mucosal fibroblasts (fBMFs). Our results indicate that the aberrantly overexpressed H1

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6

Peng, Chih-Yu, Yi-Wen Liao, Ming-Yi Lu, Chieh-Mei Yang, Pei-Ling Hsieh, and Cheng-Chia Yu. "Positive Feedback Loop of SNAIL-IL-6 Mediates Myofibroblastic Differentiation Activity in Precancerous Oral Submucous Fibrosis." Cancers 12, no. 6 (2020): 1611. http://dx.doi.org/10.3390/cancers12061611.

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Oral submucosal fibrosis (OSF) is a premalignant disorder of the oral cavity, and areca nut chewing is known to be a major etiological factor that could induce epithelial to mesenchymal transition (EMT) and activate buccal mucosal fibroblasts (BMFs). However, this detailed mechanism is not fully understood. In this study, we showed that the upregulation of Snail in OSF samples and fibrotic BMFs (fBMFs) may result from constant irritation by arecoline, a major alkaloid of the areca nut. The elevation of Snail triggered myofibroblast transdifferentiation and was crucial to the persistent activat

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7

Parikh, Pratyush. "A short review: Oral Submucous Fibrosis (OSMF)." International Journal of Pharmaceutical Research and Applications 10, no. 2 (2025): 82–84. https://doi.org/10.35629/4494-10028284.

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Oral submucous fibrosis (OSF) is a chronic condition characterized by abnormal collagen deposition in the oral submucosa, resulting in tissue scarring, dysphagia, and trismus. OSF is considered precancerous, with a transformation rate to malignancy ranging from 1.5% to 15%. This condition significantly impacts quality of life due to symptoms such as ulceration, xerostomia, and a burning sensation. This review provides a comprehensive analysis of OSF, focusing on its molecular mechanisms, diagnostic biomarkers, and therapeutic strategies. Betel nut chewing is a major risk factor, particularly p

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8

Nayak, Meghanand T., Anjali Singh, Rajiv S. Desai, and S. S. Vanaki. "Immunohistochemical Analysis of Vimentin in Oral Submucous Fibrosis." Journal of Cancer Epidemiology 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/549041.

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Background. Oral submucous fibrosis (OSF), a precancerous condition, is characterized by abnormal accumulation of collagen fibers in oral submucosa. Vimentin is a Class 2 intermediate filament (IF) and primarily expressed in cells of mesenchymal origin. Vimentin is also found to be involved in cell growth, cell cycling, and tumour differentiation.Objective. The purpose of the study was to compare the expression of vimentin in various histological grades of OSF.Materials and Methods. To assess the immunohistochemical expression of vimentin in 20 mild cases of OSF, 20 severe cases of OSF, and te

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9

Acharya, Siddharth, Sourab Kumar, Abhishek Jadhav, Priyadharshini, Faraz S., and Prince S. "Oral Submucous Fibrosis: A Case Report." International Journal of Current Research and Review 13, no. 05 (2021): 152–54. http://dx.doi.org/10.31782/ijcrr.2021.sp285.

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Introduction: Oral submucous fibrosis (OSF) is an insidious chronic disease affecting the mucosa of any part of the oral cavity and occasionally extending into the pharynx and esophagus. It occurs at any age but is most commonly seen in young adults between 25 and 35 years (2nd–4th decade). Characteristic male preponderance is reported in the literature with strong association with the chewing of smokeless tobacco. Aims: To find a provisional diagnosis of oral submucous fibrosis. Case Report: The present case report describes a case of OSF in a 40-year-old male patient. Discussion: The frequen

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10

Bhattacharjee, Tathagata, Supratim Ghosh, Dipto De, Pratik Sarkar, and Jay Gopal Ray. "Comparative analysis of blood vessel morphometry in advanced oral submucous fibrosis and malignancy associated with oral submucous fibrosis." Journal of Oral and Maxillofacial Pathology 29, no. 1 (2025): 12–17. https://doi.org/10.4103/jomfp.jomfp_89_24.

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Abstract Introduction: Oral submucous fibrosis (OSF) is a potentially malignant disorder of oral cavity. The vascularity of submucosa in this disease can predict its malignant transformation. Aim: In this study, attempts have been made to investigate different parameters of vascularity, such as mean vascular area, luminal diameter etc., in advanced OSF and make a comparison with malignancy associated with OSF. Materials and Methods: Incisional biopsy was taken from clinically diagnosed cases of advanced OSF and malignancy associated with OSF. Sections were prepared and stained with haematoxyli

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