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1

Ma, Ying-Hui, Gang Liu, and Jie Yang. "Application of Flap in Repairing Defect of Orbital Tumor." Nepalese Journal of Cancer 3, no. 1 (2019): 24–27. http://dx.doi.org/10.3126/njc.v3i1.25911.

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Introduction: Orbital tumors can extensively damage the upper and lower eyelid, peri-orbital skin, periorbital peri-bulbar tissue and eyeball. The complete removal of the tumor and the tissue destroyed by the tumor often leaves a large tissue defect area. Therefore, the application of flap in repairing defect after exenteration of orbital tumor is of paramount importance. The objective of this study is to investigate the clinical value of skin fl ap in repairing defect after exenteration of orbital tumor.
 Methods: From January 2008 to December 2017, there were 101 patients with orbital t
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Sharma, Ramlal, Kalpana Sharma, Deepti Parmar, Vineet Tanwar, Suresh Thakur, and Sarita Asotra. "Excision of massive orbital schwannoma through anterior orbital approach." Indian Journal of Ophthalmology - Case Reports 3, no. 3 (2023): 814–16. http://dx.doi.org/10.4103/ijo.ijo_3099_22.

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Orbital schwannomas are rare, benign, slowly progressing, encapsulated tumors arising from Schwann cells of the peripheral sheath of the third, fourth, and sixth cranial nerves and ciliary ganglion. The present case is of a 32-year-old male with painless protrusion of left eye for 4 years. It was radiologically diagnosed as retro-orbital hemangioma, but histopathologic examination of the orbital tumor showed orbital schwannoma. The rarity of orbital schwannomas among orbital tumors and improvement in vision along with retained eyelid functions despite excision of a massive tumor make this a un
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Lisani, Silmi Lisani, Agus Supartoto, Purjanto Tepo Utomo, Banu Aji Dibyasakti, and Datu Respatika. "REVEALING ORBITAL TUMORS: 2-YEAR EVALUATION IN CLINICAL PROFILE, HISTOPATHOLOGICAL FEATURES AND SURGICAL TECHNIQUE." Ophthalmologica Indonesiana 49, S1 (2024): 157–64. http://dx.doi.org/10.35749/vbeczx79.

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Introduction: Incidence of orbital tumors is relatively low, but the delay in diagnosis, even if benign, can lead to vision loss and deformity. Purposes: This study aims to review clinical and demographic information of orbital tumors in Sardjito General Hospital, Yogyakarta. Method: We retrospectively reviewed clinical data of 138 patients who diagnosed with orbital tumors during July 2021 - March 2023. Data extracted included clinical characteristics, operative procedures, and histopathologic characteristics of orbital tumor. Result: There were 138 orbital tumors managed at hospital during 2
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Ningrom, Ira Citra, Andi Muh Maulana, Susiyadi Susiyadi, and Raudatul Janah. "Karakteristik Pasien Tumor Orbita Di PMN RS Mata Cicendo Bandung Periode 2017-2018." Herb-Medicine Journal 4, no. 2 (2021): 68. http://dx.doi.org/10.30595/hmj.v4i2.10380.

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Orbital tumors are tumors that occur in the orbital area where they can affect the outside of the orbit and the inside of the orbit. At present, it is still rare to report the prevalence of orbital tumors in the world. In developing countries such as Indonesia, reports on the incidence of orbital tumors are also rarely reported. Diagnosis and appropriate therapy if we recognize the characteristics of these orbital tumors. The purpose of this study was to determine the characteristics of orbital tumor patients at PMN Cicendo Eye Hospital Bandung. This research is a descriptive observational stu
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Poudyal, Prija, Diwa Hamal, and Pawan Shrestha. "Orbital Tumors and Tumor like Lesions: A Hospital Based Study." Journal of Nepal Health Research Council 20, no. 01 (2022): 26–32. http://dx.doi.org/10.33314/jnhrc.v20i01.3727.

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Background: Orbital tumors have rare incidence, still they play a significant role in terms of morbidity and mortality. Orbital tumors may be primary, secondary or metastatic. These consist of benign and malignant lesions with extreme variations in pediatric and adult groups. These lesions can have acute or chronic onset, slow to rapid progression with or without bony destructions leading to vision loss, deformity and sometimes death. Methods: This retrospective cross-sectional study was carried out in the Department of Ophthalmic Pathology and Laboratory Medicine in Biratnagar Eye Hospital. F
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6

Gąsiorowski, Krzysztof, Michał Gontarz, Tomasz Marecik, et al. "Risk Factors for Orbital Invasion in Malignant Eyelid Tumors, Is Orbital Exenteration Still Necessary?" Journal of Clinical Medicine 13, no. 3 (2024): 726. http://dx.doi.org/10.3390/jcm13030726.

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Basal cell carcinoma is the most common malignant skin tumor of the eyelids in Caucasians, followed by squamous cell carcinoma and sebaceous gland carcinoma. The primary treatment for these tumors is radical excision. In cases where malignant eyelid tumors are advanced and have invaded the orbit, orbital exenteration is necessary. In this retrospective study, we aimed to determine the correlation between the risk of orbital infiltration and various factors like tumor location, size, histological type, and patient age. This study revealed that tumors in multiple regions increased the risk of or
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7

Font, Ramon L. "Orbital Carcinoid Tumor." Archives of Ophthalmology 109, no. 3 (1991): 315. http://dx.doi.org/10.1001/archopht.1991.01080030017003.

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8

Debnam, J. Matthew, Rory R. Mayer, Bita Esmaeli, Jeffrey S. Weinberg, Franco DeMonte, and Nandita Guha-Thakurta. "Three-Dimensional Multidetector CT for Anatomic Evaluation of Orbital Tumors." Journal of Ophthalmology 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/674230.

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Intricate resection and complex reconstructive procedures often required for primary and metastatic orbital tumors are facilitated by accurate imaging. A three-dimensional (3D) image can be reconstructed from source axial multidetector computed tomography (MDCT) images to visualize orbital tumors. To assess the utility of 3D images in this setting, the 3D images were reconstructed retrospectively for 20 patients with an orbital tumor and compared to two-dimensional (2D) orthogonal MDCT studies. Both types of images were assessed for their capacity to show the bony orbital walls and foramina, e
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9

Awan, Muhammad, Lea Carter, Heidi Mina, and Jorge Agi. "Recurrence of Benign Orbital Solitary Fibrous Tumor." International Journal of Ophthalmology and Clinical Research 12, no. 1 (2025): 1–3. https://doi.org/10.23937/2378-346x/1410159.

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Orbital solitary fibrous tumors are rare, accounting for less than 1% of all orbital tumors. These tumors are typically benign and surgical excision is curative, although recurrence of the neoplasm may occur after surgery. We report a case of a recurrent orbital solitary fibrous tumor in a 30-year-old female patient.
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10

Dimpi, Sinha, Sharma Sukrity, Kale Sudhir Kumar, Gorur Mohammed Imran, and Kaur Tripti. "Extramammary orbital myofibroblastoma: a rare orbital tumor." Orbit 40, no. 1 (2020): 55–59. http://dx.doi.org/10.1080/01676830.2020.1711781.

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11

Sukmawati, Ni Luh Putu Nurindah, Putu Yuliawati, and Ni Made Laksmi Utari. "Melanoma maligna orbita: sebuah laporan kasus." Intisari Sains Medis 13, no. 1 (2022): 258–63. http://dx.doi.org/10.15562/ism.v13i1.1269.

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Introduction: Orbital melanoma (OM) is the most common type of primary intraocular neoplasm in adults. Although the incidence of OM is only 5% of melanoma tumors, OM causes death in 13% of melanoma tumors. The management of orbital melanoma originating from the uveal tissue is still controversial between surgical and nonsurgical therapy. Case Report: A male patient, 63 years old, complained that the patient's right eye was said to have appeared a lump since five months ago with a size of 6 x 6 x 7 cm, blackish red in color with clinical signs of malignancy. The patient underwent orbital exente
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12

Mohammad, Najah K. "Orbital tumors: A retrospective analysis of cases from Iraq and orbital anatomical perspectives." Surgical Neurology International 16 (February 28, 2025): 62. https://doi.org/10.25259/sni_38_2025.

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Background With its vital ocular and adnexal structures, the orbit may be affected by a wide array of neoplasms, including primary, secondary, and metastatic neoplasms. These lesions pose significant diagnostic and therapeutic challenges in view of complex orbital anatomy and overlapping clinical presentations. This study aimed to analyze the epidemiology, clinical features, refractive impacts, and management outcomes of orbital tumors, providing insights to optimize diagnosis and treatment strategies. Methods This study retrospectively analyzes 22 patients who had a presentation of orbital tu
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13

Singh, Srishti, Bagyam Raghavan, Sivaramalingam Geethapriya, et al. "The unforeseen orbital tumor." Indian Journal of Radiology and Imaging 30, no. 3 (2020): 386. http://dx.doi.org/10.4103/ijri.ijri_73_20.

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14

Paganelli, B., J. Meney, J. P. Nordmann, and A. Bennedjaï. "Orbital solitary fibrous tumor." Journal Français d'Ophtalmologie 47, no. 9 (2024): 104297. http://dx.doi.org/10.1016/j.jfo.2024.104297.

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15

NARAGHI, M. "Endoscopic Orbital Tumor Surgery." Otolaryngology - Head and Neck Surgery 133, no. 2 (2005): P253. http://dx.doi.org/10.1016/j.otohns.2005.05.623.

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Yang, Ya-Yun, Yung-Hsiang Hsu, and Tzu-Lun Huang. "Orbital solitary fibrous tumor." Tzu Chi Medical Journal 27, no. 1 (2015): 35–37. http://dx.doi.org/10.1016/j.tcmj.2013.09.007.

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17

Connelly, Patrick J. "Orbital Carcinoid Tumor-Reply." Archives of Ophthalmology 109, no. 3 (1991): 316. http://dx.doi.org/10.1001/archopht.1991.01080030017004.

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18

Erb-Eigner, Katharina, Patrick Asbach, Sa-Ra Ro та ін. "DCE-MR imaging of orbital lesions: diagnostic performance of the tumor flow residence time τ calculated by a multi-compartmental pharmacokinetic tumor model based on individual factors". Acta Radiologica 60, № 5 (2018): 643–52. http://dx.doi.org/10.1177/0284185118795324.

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Background Differentiating benign from malignant orbital lesions by imaging and clinical presentation can be challenging. Purpose To differentiate benign from malignant orbital masses using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) based on tumor flow residence time τ calculated with the aid of a pharmacokinetic tumor model. Material and Methods Sixty patients with orbital masses were investigated by 3-T MRI including dynamic sequences. The signal intensity-time curve after i.v. contrast medium administration within lesions was approximated by Gd-concentration profiles on
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19

E, Hasan, and Bushager F. "Spheno-orbital Meningiomas: A Case Report." Journal of the Bahrain Medical Society 34, no. 3 (2022): 43–46. http://dx.doi.org/10.26715/jbms.34_3_7.

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Spheno-orbital meningiomas are benign tumors. They arise intracranially from the sphenoid ridge arachnoid villi cap cells, extending into the orbit. Herein, the authors report a case of a 50-year-old female who presented to Ophthalmology department with a complaint of right eye proptosis. Magnetic resonance imaging and biopsy showed a right sphenoid-orbital meningioma. The tumor was excised and the patient symptomatically improved. Patient had gross tumor reduction for right sphenoidal orbital extra-axial brain tumor with hyperostosis of the lateral wall of the orbit and sphenoidal ridge.
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20

Ali, Hussein Abbas, Ali Moheiseen Al-Taee Rajaa, J.I. Al-Shammari Mohammed, and A. Al-fahham Ali. "Epidemiology and Classification of Cystic Benign Orbital Tumors: A Review Article." INTERNATIONAL JOURNAL OF HEALTH & MEDICAL RESEARCH 03, no. 08 (2024): 573–77. https://doi.org/10.5281/zenodo.13283243.

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Benign orbital tumor is known to be with a broad variation in the clinical features and findings. Tumors in this small cavity could quickly result in crucial symptoms in vision, even though complete loss of vision. These tumors may be infectious, inflammatory or neoplastic. Management and follow up may differ based on the tumor type, site, and spread into other systems. Because of what is known that the orbital cavity constitutes a small space, so that tiny projections like that observed with tumors and infection could result in huge physiologic disorders in near structures leading to anatomic
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21

Navarro-Perea, Carmen, Cristina Calleja-García, Álvaro Bengoa-González, María-C. Garrido, Enrique Mencía-Gutiérrez, and Silvia Pérez-Trigo. "Orbital Solitary Fibrous Tumor: Four Case Reports—Clinical and Histopathological Features." Case Reports in Ophthalmological Medicine 2021 (June 9, 2021): 1–9. http://dx.doi.org/10.1155/2021/5822859.

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Purpose. To retrospectively describe the clinical characteristics, management, and outcomes of four cases of orbital solitary fibrous tumor (SFT). In one patient, we present an ultrasonic aspirator system for tumor removal. Methods. Four patients with orbital SFT were selected: one patient with orbital SFT, another patient with frontal and ethmoidal SFT and orbital affectation with high rates of recurrence, the third patient with frontal lobe SFT and orbital invasion with multiple recurrences, and the fourth case with a history of craniopharyngioma surgery and SFT located on the orbital apex.
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22

Knox, Robert J., James W. Gigantelli, and Bryan P. Arthurs. "Recurrent Orbital Inflammation From Metastatic Orbital Carcinoid Tumor." Ophthalmic Plastic and Reconstructive Surgery 17, no. 2 (2001): 137–39. http://dx.doi.org/10.1097/00002341-200103000-00013.

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Muhammad Izza Fachruriza Kirom, Delfitri Lutfi, Etty Hary Kusumastuti, and Dyah Fauziah. "Orbital tumors: the relationship of histopathological examination results and clinical characteristics: A literature review." Magna Scientia Advanced Research and Reviews 12, no. 2 (2024): 351–61. https://doi.org/10.30574/msarr.2024.12.2.0219.

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Orbital tumors, which can be neoplastic or non-neoplastic, vary in their clinical impact, ranging from cosmetic concerns to severe complications like vision loss or death in metastatic cases. These tumors are classified based on their cellular origin, including hematolymphoid, vascular, neurogenic, and others, to aid in diagnosis, prognosis, and treatment. Clinically, orbital tumors present with symptoms such as proptosis, decreased visual acuity, diplopia, pain, and inflammation, which are key diagnostic indicators. Early detection through imaging techniques like MRI and CT scans, along with
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24

Lubis, Rodiah Rahmawaty, Cut Adeya Adella, and Lokot Donna Lubis. "Relationship between Superoxide Dismutase Manganese Gene Polymorphism and Eye Tumors." Open Access Macedonian Journal of Medical Sciences 9, A (2021): 229–32. http://dx.doi.org/10.3889/oamjms.2021.5968.

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ABSTRACT
 
 Background: Orbital tumor in Indonesia is one of the eye health problems that can cause blindness. The impact caused by orbital tumors on patients is quite large because it can result in blindness and even death due to its metastatic nature. The role that SOD plays in cancer biology is not well understood, most studies showing a more oxidative state, characterized by increased intracellular ROS, particularly superoxide.
 Objective: To determine the relationship between Manganese Superoxide Dismutase (SOD2) gene polymorphisms and the incidence of orbital tumors in Med
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Novelli, Giorgio, Marco Gramegna, Gabriele Tonellini, et al. "Orbital Osteoblastoma: Technical Innovations in Resection and Reconstruction Using Virtual Surgery Simulation." Craniomaxillofacial Trauma & Reconstruction 9, no. 3 (2016): 271–76. http://dx.doi.org/10.1055/s-0036-1584397.

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Osteoblastoma is a benign tumor of bone, representing less than 1% of bone tumors. Craniomaxillofacial localizations account for up to 15% of the total and frequently involve the posterior mandible. Endo-orbital localization is very rare, with most occurring in young patients. Very few of these tumors become malignant. Orbital localization requires radical removal of the tumor followed by careful surgical reconstruction of the orbit to avoid subsequent aesthetic or functional problems. Here, we present a clinical case of this condition and describe a surgical protocol that uses and integrates
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Schick, Uta, Joris Bleyen, Alan Bani, and Werner Hassler. "Management of meningiomas en plaque of the sphenoid wing." Journal of Neurosurgery 104, no. 2 (2006): 208–14. http://dx.doi.org/10.3171/jns.2006.104.2.208.

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Object The authors present their findings on growth patterns in a large series of surgically treated meningiomas en plaque of the sphenoid wing. Methods A retrospective case analysis was performed in 67 patients (53 of whom were female) harboring meningiomas en plaque originating from the sphenoid wing, who underwent surgery between 1991 and 2002. The standard surgical approach consisted of pterional craniotomy and extradural resection of any infiltrated bone. The intracranial tumor was removed, and the dura mater and bone were reconstructed. The follow-up period ranged from 6 to 118 months (m
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Mahmoud, Anis, Hager Touil, Fadima Hann, and Riadh Messaoud. "Case Report: an unusual orbital tumor." F1000Research 12 (June 19, 2023): 700. http://dx.doi.org/10.12688/f1000research.130056.1.

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Introduction: Orbital lipoma is an extremely rare tumor, representing less than 1% of all orbital tumors. We review the literature and describe the presentation, the differential diagnosis and the management of this tumor. Case report: We report the case of a 63-year-old patient who was referred for a diplopia with recent hemi-cranial headache. Physical examination showed no exophthalmos nor decrease in visual acuity. The patient complained of diplopia on elevation and oculomotricity examination showed limited elevation of the right eye. The Hess Lancaster test was in favor of a limited course
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Mahmoud, Anis, Hager Touil, Fadima Hann, and Riadh Messaoud. "Case Report: an unusual orbital tumor." F1000Research 12 (October 27, 2023): 700. http://dx.doi.org/10.12688/f1000research.130056.2.

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Introduction Orbital lipoma is an extremely rare tumor, representing less than 1% of all orbital tumors. We review the literature and describe the presentation, the differential diagnosis and the management of this tumor. Case report We report the case of a 63-year-old patient who was referred for a diplopia with recent hemi-cranial headache. Physical examination showed no exophthalmos nor decrease in visual acuity. The patient complained of diplopia on elevation and oculomotricity examination showed limited elevation of the right eye. The Hess Lancaster test was in favor of a limited course o
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Kumar, Rajeev, Kapil Sikka, C. Preetam, Rakesh Kumar, and Prashant Durgapal. "A Rare Association of Inflammatory Myofibroblastic Tumor of Maxilla and Idiopathic Orbital Inflammatory Disease." An International Journal Clinical Rhinology 6, no. 1 (2013): 41–43. http://dx.doi.org/10.5005/jp-journals-10013-1146.

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ABSTRACT Inflammatory myofibroblastic tumor (pseudotumor) is a rare tumor belonging to the family of fibrous mesenchymal tumors. Though it usually involves lungs, but extrapulmonary site involvement, especially head and neck region is rare. In this paper, we are presenting a 26-year-old male patient, with inflammatory myofibroblastic tumor of maxilla, with a rare association with a prior history of idiopathic orbital inflammatory disease, treated medically. The patient was treated surgically with complete excision of the pathology from maxilla. This case report intents to review the controvers
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Polishchuk, M. E., M. S. Gudym, D. V. Shchehlov, et al. "Surgical treatment of tumors of the orbit and cranio-orbital region." Archive of Ukrainian Ophthalmology 9, no. 1 (2021): 43–48. http://dx.doi.org/10.22141/2309-8147.9.1.2021.229523.

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Background. Surgical treatment of space-occupying orbital masses and cranio-orbital tumors is relevant due to the features of the diagnosis and surgical stage of treatment because of the dense arrangement of neurovascular and muscular structures in a small orbital space. The purpose was to determine the features of the surgical treatment of orbital and cranio-orbital tumors. Mate­rials and methods. A retrospective analysis of 102 patients (76 women, 26 men) with orbital and cranio-orbital tumors who were treated at the Department of Neurosurgery 2 at Kyiv City Clinical Emergency Hospital from
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FRIEDRICH, REINHARD E., and CHRISTIAN HAGEL. "Malignant Peripheral Nerve Sheath Tumor (MPNST) Arising from Orbital Plexiform Neurofibroma in a Small Child With Neurofibromatosis Type 1." Cancer Diagnosis & Prognosis 5, no. 2 (2025): 244–54. https://doi.org/10.21873/cdp.10436.

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Background/Aim: Neurofibromatosis type 1 (NF1) is an autosomal dominant hereditary tumor predisposition syndrome. In approximately 30% of cases, plexiform neurofibromas (PNFs) are identified, which are precursor lesions for malignant peripheral nerve sheath tumors (MPNSTs). MPNST is a major cause of the reduced life expectancy of NF1 patients. Case Report: The patient, a two-year-old at the time of surgical treatment, had been diagnosed with an orbital nerve sheath tumor causing lid swelling and ptosis since birth. The tumor showed disproportionately rapid growth, leading to increasing functio
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Hong, Sukwoo, and Takayuki Hara. "Hybrid nerve sheath tumor in the orbit: A case report and review of literature." Surgical Neurology International 10 (December 20, 2019): 250. http://dx.doi.org/10.25259/sni_542_2019.

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Background: In neurosurgical practice, we rarely encounter hybrid nerve sheath tumors (HNST) in the orbit. We recently had a patient of this rare tumor. We believe that this is the first report where we resected the tumor transcranially. Case Description: A 54-year-old male presented with the left proptosis and intraconal tumor of 43 mm. We performed fronto-orbital craniotomy to resect the tumor mass. His proptosis completely improved and discharged home with a modified Rankin Scale of 1. Conclusion: Transcranial resection of orbital HNST was a safe and effective way to treat. Since we do not
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Woo, David, James Leong, Dale Waring, Alok Sharma, and Peter Martin. "Orbital Gastrointestinal Stromal Tumor Metastasis." Orbit 31, no. 2 (2012): 129–31. http://dx.doi.org/10.3109/01676830.2011.638100.

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Mogaddam, Aliakbar Saber, Bahram Memar, Amir Aledavood, and Alireza Eslampoor. "Isolated Orbital Endodermal Sinus Tumor." Ophthalmic Plastic & Reconstructive Surgery 23, no. 6 (2007): 477–79. http://dx.doi.org/10.1097/iop.0b013e31815928de.

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Shyla, P. R., Reshmi M. Nair, and Thara Somanathan. "Rare case of orbital tumor." Indian Journal of Otolaryngology and Head & Neck Surgery 59, no. 2 (2007): 174–75. http://dx.doi.org/10.1007/s12070-007-0052-z.

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Yuen, Hunter K. L. "Orbital Sclerosing Extramedullary Hematopoietic Tumor." Archives of Ophthalmology 123, no. 5 (2005): 689. http://dx.doi.org/10.1001/archopht.123.5.689.

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Reyes-Soto, Gervith, Jose F. Carrillo-Hernández, Bernardo Cacho-Díaz, et al. "Surgical treatment of orbital tumors in a single center: Analysis and results." Surgical Neurology International 15 (April 5, 2024): 122. http://dx.doi.org/10.25259/sni_1016_2023.

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Background: Orbital tumors, arising within the bony orbit and its contents, present diverse challenges due to their varied origins and complex anatomical context. These tumors, classified as primary, secondary, or metastatic, are further subdivided into intraconal and extraconal based on their relationship with the muscle cone. This classification significantly influences surgical approach and management. This study highlights surgical experiences with orbital tumors, underscoring the importance of tailored surgical approaches based on the lesion’s site and its proximity to the optic nerve. Me
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Lystratenko, O. I., A. M. Kardash, D. O. Lystratenko, A. V. Vashchenko, and O. F. Smyrnova. "Diagnosis and Surgical Treatment of Orbital Tumors of Various Localizations and Histostructures." Neuroscience and Neurological Surgery 6, no. 1 (2020): 01–11. http://dx.doi.org/10.31579/2578-8868/111.

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The article reviews and analyzes the results of treatment of 32 patients with orbital tumors operated in the clinic, neurosurgery until the period from 2015 till September 2019. Goals and objectives: coverage of clinical signs and symptoms, histology, diagnostic methods and treatment of patients operated on with orbital tumors during the period 2015-2019. Determination of optimal surgical approach to the tumors with different localization for performing the radical organ-preserving surgery, with maximal saving of visual functions, minimization of oculomotor disorders, patient disability. Mater
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Kiratli, Hayyam, Kadriye Erkan Balcı, and Gülnur Güler. "Primary orbital endodermal sinus tumor (yolk sac tumor)." Journal of American Association for Pediatric Ophthalmology and Strabismus 12, no. 6 (2008): 623–25. http://dx.doi.org/10.1016/j.jaapos.2008.06.011.

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Ghartimagar, D., A. Ghosh, MK Shrestha, et al. "Orbital lymphoma in an elderly patient." Journal of Pathology of Nepal 7, no. 1 (2017): 1124–26. http://dx.doi.org/10.3126/jpn.v7i1.16939.

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Lymphomas of the orbit and orbital adnexae are rare tumors, comprising only 1% of all non-Hodgkin’s lymphoma. Lymphomas are the most common primary orbital tumor in adults of age 60 years and older. Here we present a case of 49 year male with left upper lid swelling since 1 year who was diagnosed histopathologically as non-Hodgkin’s lymphoma of orbital region.
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Nagashima, Hiroaki, Kazuki Yamamoto, Atsufumi Kawamura, Tatsuya Nagashima, Koji Nomura, and Makiko Yoshida. "Pediatric orbital schwannoma originating from the oculomotor nerve." Journal of Neurosurgery: Pediatrics 9, no. 2 (2012): 165–68. http://dx.doi.org/10.3171/2011.11.peds1192.

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Intraorbital schwannoma is a rare tumor that constitutes approximately 1%–8% of all orbital tumors. The authors report a case of orbital schwannoma in a 5-year-old boy who was admitted to their institute with exophthalmos and ptosis of the right eye. Computed tomography scanning and MR imaging revealed a retroocular mass in the right orbit. The tumor was successfully removed via a transcranial approach. The pathological diagnosis was schwannoma that appeared to originate from the superior branch of the oculomotor nerve. Despite the rarity of these intraorbital extraocular tumors in children, s
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Wakisaka, Shinichiro, Manabu Tashiro, Shinichi Nakano, Toshihiro Kita, Hiroto Kisanuki, and Kazuo Kinoshita. "Intracranial and Orbital Metastasis of Hepatocellular Carcinoma: Report of Two Cases." Neurosurgery 26, no. 5 (1990): 863–66. http://dx.doi.org/10.1227/00006123-199005000-00021.

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Abstract Two cases of rare intracranial and orbital metastasis of hepatocellular carcinoma are presented. A 61-year-old woman was found to have a metastatic tumor in the right temporo-occipital lobe 1 year after undergoing treatment for a primary hepatoma. An osteolytic tumor was removed from the left orbit of a 58-year-old man and the primary tumor, a hepatoma, was discovered postoperatively. The intracranial and orbital tumors were verified to be hepatocellular carcinoma. Both patients died within 1 year of surgery. The relevant literature is briefly reviewed.
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Atmaca, Ali Fuat, Serkan Altınova, Abdullah Erdem Canda, et al. "Retroperitoneal Extragonadal Nonseminomatous Germ Cell Tumor with Synchronous Orbital Metastasis." Advances in Urology 2009 (2009): 1–3. http://dx.doi.org/10.1155/2009/419059.

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A huge retroperitoneal tumor with a right orbital mass was detected and proved to be an extragonadal nonseminomatous germ cell tumor on biopsy. BEP chemotherapy caused some regression in orbital mass however no change in retroperitoneal tumor size as well as serum tumor marker levels occurred. Herein, we present a rarely seen entity of extragonadal retroperitoneal nonseminomatous germ cell tumor with synchronous orbital metastases and discuss its diagnosis and management.
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Risalma, Elfi, and Ardizal Rahman. "Pediatric Primary Orbital Tumors in Dr.M. Djamil General Hospital Padang." Ophthalmologica Indonesiana 43, no. 2 (2017): 129. http://dx.doi.org/10.35749/journal.v43i2.153.

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 Introduction : Primary orbital tumors of childhood are different from tumors that occur in adults. Many are congenital with early presentation. In pediatric population, a delay in diagnosis of orbital tumors , even benign tumor can lead to vision loss and deformity. Objective : To report pediatric primary orbital tumors in Dr.M.Djamil Hospital Padang. 
 Method : A retrospective study of orbital tumors in pediatric patients admitted to DR.M.Djamil Hospital between 2003- 2016. Data were obtained from medical records which described patients characteristics based on type
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Ioakeim-Ioannidou, Myrsini, and Shannon M. MacDonald. "Evolution of Care of Orbital Tumors with Radiation Therapy." Journal of Neurological Surgery Part B: Skull Base 81, no. 04 (2020): 480–96. http://dx.doi.org/10.1055/s-0040-1713894.

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AbstractOrbital tumors are rare lesions comprising 0.1% of all tumors and less than 20% of all ocular diseases. These lesions in children and adults differ significantly in their incidence, tumor type, and treatment management. Although surgery and systemic therapies are commonly used in the management of these diseases, radiation therapy has become a widely used treatment for both benign and malignant tumors of the orbit. Radiotherapy is used as a definitive treatment to provide local control while avoiding morbidity associated with surgery for some tumors while it is used as an adjuvant trea
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Shao, Ji, Jiazhu Zhu, Kai Jin, et al. "End-to-End Deep-Learning-Based Diagnosis of Benign and Malignant Orbital Tumors on Computed Tomography Images." Journal of Personalized Medicine 13, no. 2 (2023): 204. http://dx.doi.org/10.3390/jpm13020204.

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Determining the nature of orbital tumors is challenging for current imaging interpretation methods, which hinders timely treatment. This study aimed to propose an end-to-end deep learning system to automatically diagnose orbital tumors. A multi-center dataset of 602 non-contrast-enhanced computed tomography (CT) images were prepared. After image annotation and preprocessing, the CT images were used to train and test the deep learning (DL) model for the following two stages: orbital tumor segmentation and classification. The performance on the testing set was compared with the assessment of thr
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Skarica, Rade, Boris Zdilar, Domagoj Rasic, et al. "Orbital cavernous hemangioma." Acta Chirurgica Croatica 12, no. 1 (2015): 51–54. https://doi.org/10.5281/zenodo.3534076.

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The aim of this case report was to present a patient with a benign orbital tumor, cavernous hemangioma, who presented with symptoms of compressive orbital mass: unilateral axial proptosis, with motility restriction and sudden vision loss in the left eye. Ophthalmologic examination (visual acuity, applanation tonometry, Goldmann tonometer, visual field) and radiologic examination diagnosed a benign, well circumscribed, vascular, intraconal tumor that compresses the optic nerve. Treatment was operative: lateral orbitectomy Krönlein procedure and the tumor was removed. Pathologic and pathohi
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Yan, Yu, Shuangle Li, Mi Zhou, and Qin Zhong. "Orbital fibroblastic reticular cell tumor: A case report and literature review for a rare disease." Medicine 104, no. 23 (2025): e42807. https://doi.org/10.1097/md.0000000000042807.

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Rationale: This study investigates the clinical, imaging, and pathological features of fibroblastic reticular cell tumors (FRCTs) through a retrospective analysis of a patient with FRCT, along with a review of relevant literature. Patient concerns: A 49-year-old male was admitted to our hospital because of swelling and discomfort in the right eye, occasionally accompanied by double vision, for more than 3 months. Physical examination revealed an obliquely downward right eye, ptosis, and a palpable medium–hard tumor at the supraorbital rim of the orbit. Diagnoses: An orbital B-type ultrasound,
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Jo, Kyung-Il, Yong Seok Im, Doo-Sik Kong, et al. "Multisession Gamma Knife surgery for benign orbital tumors." Journal of Neurosurgery 117, Special_Suppl (2012): 102–7. http://dx.doi.org/10.3171/2012.7.gks12780.

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Object The goal of this study was to investigate the safety and efficacy of multisession Gamma Knife surgery (GKS) in the treatment of benign orbital tumors. Methods Twenty-three patients who retained their vision despite having tumors touching their optic nerve were treated with multisession (4-fraction) GKS. The median tumor volume was 2800 mm3 (range 211–10,800 mm3), and the median cumulative margin dose was 20 Gy (range 18–22 Gy). Results The median clinical follow-up duration in these patients was 38 months (range 9–74 months). No patient experienced tumor progression in this study. In pa
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Maroon, Joseph C., John S. Kennerdell, Danko V. Vidovich, Adnan Abla, and Linda Sternau. "Recurrent spheno-orbital meningioma." Journal of Neurosurgery 80, no. 2 (1994): 202–8. http://dx.doi.org/10.3171/jns.1994.80.2.0202.

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✓ A series of 15 patients who underwent neurosurgical procedures for recurrent spheno-orbital meningioma is reported. There were 11 women and four men, with a mean age of 46 years. The mean duration between the first and second operations was 46 months. Progressive proptosis without neurological deficit was the most common symptom. All tumors were large at the time of reoperation and involved the greater and lesser wings of the sphenoid bone and the orbit. Aggressive resection in all patients resulted in no deaths and only slight morbidity, with the exception of one patient who developed blind
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