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Artykuły w czasopismach na temat "Ovarian tumor - peculiarities of evolution and progress"

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Pu, Tengda, Chengyuan Zhang, Bingfeng Su, Li Li, and Jingjing Fu. "Research progress in intratumoral heterogeneity and clinical significance of ovarian cancer." Medicine 103, no. 4 (2024): e36074. http://dx.doi.org/10.1097/md.0000000000036074.

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Intratumoral heterogeneity has been a hot topic of cancer research in recent years, which has become a part of resolving cancer metastasis, recurrence and drug resistance. Intratumoral heterogeneity shows that cells undergo different division and proliferation during the process of tumor development, and their genomic cells exist in the process of tumor development. Protein and epigenetic changes can lead to differences in proliferation, migration and invasion, sensitivity and pharmacological prognosis of tumor cells, promote sustainable development and development of cancer cells, produce gre
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Conejo-Garcia, Jose, Uciane Scarlett, Melanie Rutkowski, Jason Baird, and Stephen Fiering. "Ovarian cancer progression is controlled by phenotypic changes in dendritic cells (127.7)." Journal of Immunology 188, no. 1_Supplement (2012): 127.7. http://dx.doi.org/10.4049/jimmunol.188.supp.127.7.

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Abstract We have characterized the initiation and evolution of the immune response against a new p53-dependent model of aggressive ovarian carcinoma. In these previously healthy tumor-bearing hosts, we detect measurable anti-tumor immunity from very early stages, which is driven by infiltrating dendritic cells (DCs) and prevents steady tumor growth for prolonged periods. Coinciding with a phenotypic switch in expanding DC infiltrates, tumors become noticeable and aggressively progress to terminal disease in a comparatively much shorter time. Notably, tumor cells remain immunogenic at advanced
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Scarlett, Uciane K., Melanie R. Rutkowski, Adam M. Rauwerdink, et al. "Ovarian cancer progression is controlled by phenotypic changes in dendritic cells." Journal of Experimental Medicine 209, no. 3 (2012): 495–506. http://dx.doi.org/10.1084/jem.20111413.

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We characterized the initiation and evolution of the immune response against a new inducible p53-dependent model of aggressive ovarian carcinoma that recapitulates the leukocyte infiltrates and cytokine milieu of advanced human tumors. Unlike other models that initiate tumors before the development of a mature immune system, we detect measurable anti-tumor immunity from very early stages, which is driven by infiltrating dendritic cells (DCs) and prevents steady tumor growth for prolonged periods. Coinciding with a phenotypic switch in expanding DC infiltrates, tumors aggressively progress to t
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Adamyan, L. V., E. V. Sibirskaya, S. M. Sharkov, A. K. Fayzulin, and Anastasia V. Vechernina. "SPECIFIC MOMENTS IN THE DIAGNOSTICS OF UTERINE ADNEXA TORSION IN A 15-YEAR OLD GIRL." Russian Journal of Pediatric Surgery 23, no. 3 (2019): 154–56. http://dx.doi.org/10.18821/1560-9510-2019-23-3-154-156.

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Currently, differential diagnostics and treatment of uterine adnexal torsion (UAT) in girls is not completely solved and is not an easy one because surgical and gynecological pathologies often intersect with each other. That is why, girls with abdominal pain are to be consulted by a gynecologist. The case discussed in the article demonstrates the problem with differential diagnostics in girls with “acute abdomen”. UAT differential diagnostics is not easy because this pathology has no clear clinical picture what complicates putting a correct diagnosis. UAT in girls is an acute pathology which h
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Zhou, Ziyu, and Ziqian Sang. "Review of the Research Progress of Paclitaxel." Theoretical and Natural Science 72, no. 1 (2025): 194–98. https://doi.org/10.54254/2753-8818/2024.19390.

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Since its initial discovery in 1962, Paclitaxel has emerged as a highly esteemed drug in the realm of cancer therapy, garnering widespread attention owing to its potent anticancer properties. This paper delves into the pivotal milestones in the evolution of Paclitaxel, comprehensively outlining its historical context, manufacturing methodologies, mode of action, and clinical utilization. Originating from the bark of the Pacific yew tree, the drug was initially procured through natural extraction, posing challenges due to scarcity of raw material. Over time, advancements in biosynthetic and sem
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Prokopenko, Petr G., Valentina Poltoranina, Kirill I. Zhordania, Olga Petrenko, Innokenty M. Mokhosoev, and Alexander A. Terentiev. "Problems and Perspectives in Diagnosis and Prevention of Ovarian Tumor Diseases." May 29, 2011. https://doi.org/10.5281/zenodo.7770.

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A set of embryonic proteins - potential markers for ovarian tumors is presented. More than ten new embryonic proteins have been tested, but no one strictly specific protein marker for diagnosis of ovarian tumors has been revealed. SOVA-1 is the most perspective marker for today. The special attention is given to peculiarities of evolution and mechanisms of early distribution of the tumor process. The role of pregnancy and “pregnancy specific glycoprotein”- PSG as a way of the ovary tumor disease prevention is discussed. An attempt to realize sources and logic of the disease is unde
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Poulain, Marine, Jessica Vandame, Chloé Tran, Sonia Koutchinsky, Paul Pirtea, and Jean-Marc Ayoubi. "Fertility preservation in borderline ovarian tumor patients and survivors." Hormone Molecular Biology and Clinical Investigation, July 6, 2020. http://dx.doi.org/10.1515/hmbci-2019-0072.

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AbstractBorderline ovarian tumors (BOTs) represent around 15% of all epithelial ovarian cancer. Around one third of those patients is under 40 and has not completed childbearing when the tumor is diagnosed. Cancer survivors are more and more concerned about their future fertility since a large proportion of those with BOTs are young. Whatever the tumor stage, information regarding future fertility after treatment and fertility preservation (FP) options must be delivered to all patients before treatment. A multidisciplinary team will discuss and propose personalized treatment and FP strategies.
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Jiang, Guangyi, Junjie Hong, Feng Shao, et al. "Evolution of Immunotherapy for Ovarian Cancer from a Bird’s-Eye Perspective: A Text-Mining Analysis of Publication Trends and Topics." Frontiers in Oncology 12 (February 24, 2022). http://dx.doi.org/10.3389/fonc.2022.795129.

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ObjectivesOvarian tumors are among the most prominent gynecological malignancies and have a poor prognosis. Immunotherapy has undergone incredible progress in the past two decades. Our study aimed to use a bibliometric approach to identify research trends in ovarian cancer immunotherapy.MethodsLiterature on this topic published from 2000–2020 was retrieved from the Web of Science Core Citation database and analyzed using the bibliometric analysis software VOSviewer and CiteSpace.ResultsA total of 1729 articles on ovarian cancer immunotherapy published from January 2000 to December 2020 were id
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Spano, Alessandra, and Luigi Sciola. "Polyploid cell dynamics and death before and after PEG-treatment of a NIH/3T3 derived culture: vinblastine effects on the regulation of cell subpopulations heterogeneity." Cell Division 18, no. 1 (2023). http://dx.doi.org/10.1186/s13008-023-00100-y.

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Abstract Background Neoplastic subpopulations can include polyploid cells that can be involved in tumor evolution and recurrence. Their origin can be traced back to the tumor microenvironment or chemotherapeutic treatment, which can alter cell division or favor cell fusion, generating multinucleated cells. Their progeny, frequently genetically unstable, can result in new aggressive and more resistant to chemotherapy subpopulations. In our work, we used NIHs cells, previously derived from the NIH/3T3 line after serum deprivation, that induced a polyploidization increase with the appearance of c
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