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1

Edwards, B. J., A. Desai, J. Tsai, et al. "Elevated Incidence of Fractures in Solid-Organ Transplant Recipients on Glucocorticoid-Sparing Immunosuppressive Regimens." Journal of Osteoporosis 2011 (2011): 1–8. http://dx.doi.org/10.4061/2011/591793.

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This study was conducted to assess the occurrence of fractures in solid-organ transplant recipients.Methods. Medical record review and surveys were performed. Patients received less than 6 months of glucocorticoids.Results. Of 351 transplant patients, 175 patients provided fracture information, with 48 (27.4%) having fractured since transplant (2–6 years). Transplants included 19 kidney/liver (50% male), 47 kidney/pancreas (53% male), 92 liver (65% male), and 17 pancreas transplants (41% male). Age at transplant was50.8±10.3years. Fractures were equally seen across both genders and transplant
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2

Chiu, M. Y., S. M. Sprague, D. S. Bruce, E. S. Woodle, J. R. Thistlethwaite, and M. A. Josephson. "Analysis of fracture prevalence in kidney-pancreas allograft recipients." Journal of the American Society of Nephrology 9, no. 4 (1998): 677–83. http://dx.doi.org/10.1681/asn.v94677.

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Fractures occur in 11 to 26% of renal allograft recipients after transplantation despite improvements in bone and mineral disorders. This high fracture rate is likely a consequence of accelerated osteopenia. The cause of posttransplant bone loss is multifactorial, and patients with insulin-dependent diabetes mellitus and renal failure may have additional fracture risks such as low turnover bone disease. This retrospective cohort study was undertaken to determine the long-term incidence and the potential risk factors of posttransplant fractures in patients with insulin-dependent diabetes mellit
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Dodds, Wylie J., Andrew J. Taylor, Scott J. Erickson, and Thomas L. Lawson. "Traumatic Fracture of the Pancreas." Journal of Computer Assisted Tomography 14, no. 3 (1990): 375–78. http://dx.doi.org/10.1097/00004728-199005000-00009.

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Kalker, Alan J., John D. Pirsch, Dennis Heisey, et al. "Foot problems in the diabetic transplant recipient." Clinical Transplantation 10, no. 6pt1 (1996): 503–10. http://dx.doi.org/10.1111/j.1399-0012.1996.tb00736.x.

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AbstractDiabetic transplant recipients are at a high risk for foot pathology leading to amputation. This retrospective study from 1/85 to 2/92 examines the risk of foot complications in a population (n=340) of diabetic renal and combined renal/pancreas transplant recipients. All groups suffered high lower extremity amputation and foot fracture rates. Patients with better circulation and protective sensation intact fared better. Smoking had a profoundly negative effect on the amputation rate as did an amputation prior to the transplant. Patients with pretransplant dialysis were at a higher risk
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Arslan, Engin. "Isolated Pancreas Fracture after a Go-Kart Accident." British Journal of Medicine and Medical Research 3, no. 2 (2013): 288–93. http://dx.doi.org/10.9734/bjmmr/2013/2487.

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Sasaki, Takashi, Ryo Kanata, and Naoki Sasahira. "Needle fracture during endoscopic ultrasound-guided fine needle aspiration using a needle with a side hole." Endoscopy International Open 06, no. 05 (2018): E553—E557. http://dx.doi.org/10.1055/a-0587-4827.

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Abstract Background and study aims Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is widely performed to obtain pathological evidence from several parts of the body. Major complications of EUS-FNA are bleeding, pancreatitis, and abdominal pain. Needle fracture is a rare complication of EUS-FNA and only a few relevant reports are available. Here, we report a case of needle fracture during EUS-FNA using a needle with a side hole. A 61-year-old man underwent EUS-FNA of the uncinate process of the pancreas to confirm malignancy. A 20-gauge needle with a side hole was used to punctur
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7

Walther, Paul. "Cryo-Fracturing and Cryo-Planing for In-Lens Cryo-SEM, Using a Newly Designed Diamond Knife." Microscopy and Microanalysis 9, no. 4 (2003): 279–85. http://dx.doi.org/10.1017/s1431927603030496.

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High-pressure frozen rat pancreas tissue samples were cryo-fractured and cryo-sectioned with a diamond knife in the microtome of a freeze-etching device. The bulk fracture faces and block faces were investigated in the frozen-hydrated state by use of a cryo-stage in an in-lens SEM. With this combination, relevant biological structures can be investigated with a few nanometers resolution in a near lifelike state, preventing the artifacts of conventional fixation techniques. Compared to TEM replica techniques, the presented method is more versatile since no replica cleaning is necessary. Additio
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8

Govaert, M. J., K. J. Ponsen, L. de Jonge, L. Th de Wit, and H. Obertop. "Fracture of the pancreas in two patients after a go‐kart accident." HPB 3, no. 1 (2001): 3–6. http://dx.doi.org/10.1080/136518201753173872.

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9

Lanham, Stuart A., Dominique Blache, Richard O. C. Oreffo, Abigail L. Fowden, and Alison J. Forhead. "Pancreas deficiency modifies bone development in the ovine fetus near term." Journal of Endocrinology 252, no. 1 (2022): 71–80. http://dx.doi.org/10.1530/joe-21-0189.

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Hormones have an important role in the regulation of fetal growth and development, especially in response to nutrient availability in utero. Using micro-CT and an electromagnetic three-point bend test, this study examined the effect of pancreas removal at 0.8 fraction of gestation on the developing bone structure and mechanical strength in fetal sheep. When fetuses were studied at 10 and 25 days after surgery, pancreatectomy caused hypoinsulinaemia, hyperglycaemia and growth retardation which was associated with low plasma concentrations of leptin and a marker of osteoclast activity and collag
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10

Lindh, Jonatan D., Jekaterina Patrova, Buster Mannheimer, and Henrik Falhammar. "Prevalence and Incidence of Fractures in Patients With Nonfunctional Adrenal Tumors." JAMA Network Open 7, no. 4 (2024): e246453. http://dx.doi.org/10.1001/jamanetworkopen.2024.6453.

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ImportanceIt is unclear whether nonfunctional adrenal tumors (NFATs) are associated with fractures.ObjectiveTo analyze fracture frequencies in individuals with NFATs.Design, Setting, and ParticipantsA national retrospective cohort study was conducted in patients with NFATs diagnosed in Sweden between January 1, 2005, and December 31, 2019, and control participants without adrenal tumors followed up until death or the end of 2019. Individuals with a diagnosis of adrenal hormonal excess or previous malignant tumors were excluded. Sensitivity analyses were performed in subgroups of individuals wi
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11

Allison, Susan J. "Pancreas–kidney transplantation may reduce fracture risk in men with type 1 diabetes mellitus." Nature Reviews Nephrology 9, no. 3 (2013): 124. http://dx.doi.org/10.1038/nrneph.2013.3.

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12

Gothi, R., N. C. Bose, and N. Kumar. "Case report: Ultrasound demonstration of traumatic fracture of the pancreas with pancreatic duct disruption." Clinical Radiology 47, no. 6 (1993): 434–35. http://dx.doi.org/10.1016/s0009-9260(05)81069-4.

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13

Abdelilah, El Bakouri, Ahmed Elmi Abdirahim, Elwassi Anas, et al. "Pancreatic Trauma with Splenic Preservation (A Case Report)." European Journal of Medical and Health Sciences 4, no. 5 (2022): 6–9. http://dx.doi.org/10.24018/ejmed.2022.4.5.1424.

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Trauma to the pancreas is rare, occurring in 0.2 to 3% of abdominal injuries. They are associated with high mortality and morbidity if diagnosis is delayed. Their clinical symptomatology is atypical. Abdominal CT scans can diagnose pancreatic injury and rupture of the main pancreatic duct. It is important that surgeons are aware of the issues and principles of management of pancreatic injury. We report the case of a 33-year-old patient with no previous pathological history. Admitted for a closed abdominal contusion following a road traffic accident with an abdominal impact point without initia
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14

Robertson, Francis P., Harry V. M. Spiers, Wei Boon Lim, Benjamin Loveday, Keith Roberts, and Sanjay Pandanaboyana. "Intraoperative pancreas stump perfusion assessment during pancreaticoduodenectomy: A systematic scoping review." World Journal of Gastrointestinal Surgery 15, no. 8 (2023): 1799–807. http://dx.doi.org/10.4240/wjgs.v15.i8.1799.

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Tumour rupture of gastrointestinal stromal tumours (GISTs) has been considered to be a remarkable risk factor because of its unfavourable impact on the oncological outcome. Although tumour rupture has not yet been included in the current tumor-node-metastasis classification of GISTs as a prognostic factor, it may change the natural history of a low-risk GIST to a high-risk GIST. Originally, tumour rupture was defined as the spillage or fracture of a tumour into a body cavity, but recently, new definitions have been proposed. These definitions distinguished from the prognostic point of view bet
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15

Ametov, A. S., A. V. Shabunin, E. Yu Pashkova, V. B. Rumer, K. A. Amikishieva, and D. M. Antsiferova. "A patient with Chronic Calcific Pancreatitis: the Task with Many Unknowns." Doctor.Ru 22, no. 8 (2023): 55–60. http://dx.doi.org/10.31550/1727-2378-2023-22-8-55-60.

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Aim. To describe a clinical case of a patient with diabetes mellitus in the outcome of chronic calcific pancreatitis. Key points. Chronic pancreatitis is a multifaceted disease complicating a great number of body systems work. Currently, the problem of post-pancreatitis diabetes mellitus is receiving more and more attention precisely because simultaneous decrease of the endo- and exocrine functions of the pancreas without timely correction is accompanied by concomitant metabolic disorders that lead to different complaints, hiding the underlying cause. In addition to the familiar to endocrinolo
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16

Kozlova, Irina V., and Anna P. Bykova. "Osteosarcopenia in chronic pancreatitis." Terapevticheskii arkhiv 93, no. 8 (2021): 869–75. http://dx.doi.org/10.26442/00403660.2021.08.200971.

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Aim. To determine clinical features and some mechanisms of osteosarcopenia development in patients with chronic pancreatitis (CP).
 Materials and methods. A casecontrol study was conducted on the basis of the Saratov State Clinical Hospital 5 in 20152018 of patients with CP. In a study of 161 patients with CP included, the control group 30 healthy individuals. Patients were divided into groups according to the etiology of CP: 79 with toxic-metabolic CP, 82 with biliary CP. To determine the risks of low-energy fractures, 154 patients were tested with the Fracture risk assessment tool (FRAX
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17

Beaudoin, A. R., G. Grondin, A. Vachereau, P. St-Jean, and C. Cabana. "Detection and characterization of microvesicles in the acinar lumen and in juice of unstimulated rat pancreas." Journal of Histochemistry & Cytochemistry 34, no. 8 (1986): 1079–84. http://dx.doi.org/10.1177/34.8.3734418.

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Small vesicles were visualized in the lumen of rat pancreas acini by freeze-substitution and conventional electron microscopy. Microvesicles were subsequently isolated from pancreatic juice. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis revealed that these vesicles contain only one major protein. The major protein was identified by an immunoblot technique as GP-2, an 80 kD glycoprotein also found in the zymogen granule membrane. The immunocytochemical localization of rabbit anti-GP-2 and anti-amylase by the protein A-gold technique confirmed that GP-2 was associated with clusters o
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18

Ajisaka, Hideyuki, Seiichiro Okura, and Masahiro Wakasugi. "Traumatic Abdominal Wall Hernia: A Case Report of High-Energy Type without surgical Repair." Clinical Medicine Insights: Case Reports 4 (January 2011): CCRep.S7425. http://dx.doi.org/10.4137/ccrep.s7425.

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Repair of traumatic abdominal wall hernia (TAWH) has been reported to be necessary. Reported here is one case of TAWH without repair. A 27-year-old man was accidentally sandwiched between a rock and a truck and admitted to our emergency department. There was a swelling of 10 cm in the right upper quadrant of the abdomen. The enhanced computed tomographic scan demonstrated a large abdominal wall muscular defect, transverse colon protrusion, and the presence of subcutaneous emphysema at the site. Based on these findings, lacerated transverse colon entrapped in TAWH was diagnosed. The patient und
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19

Bilinskas, Mykolas J., Gintautas Dzemyda, and Mantas Trakymas. "Approximation of the Ribs-Bounded Contour in a Tomography Scan Slice." International Journal of Information Technology & Decision Making 17, no. 01 (2018): 83–102. http://dx.doi.org/10.1142/s0219622017500298.

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In this paper, a method for analyzing transversal plane images obtained by computer tomography (CT) scans is presented. A mathematical model that describes the ribs-bounded contour was created and the problem of approximation is solved by finding out the optimal parameters of the model in the least-squares sense. The paper discloses the problems that appear in building the proper model. Such a model would be useful in the registration of images independently on the patient position on the bed and of the radiocontrast agent injection. We consider the slices where ribs are visible because many i
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20

Sedik, Alaa, Mohamed Ibrahim, Abdulla Zarrouq, and Sal Wa Elhoushy. "A case with missed pancreatic injury with massive pancreatic ascites and severe traumatic pancreatic necrosis: a case report and literature review." International Surgery Journal 5, no. 9 (2018): 3156. http://dx.doi.org/10.18203/2349-2902.isj20183740.

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Despite the major advances in the field of trauma management. High grade Blunt pancreatic injury remains a disease with both high mortality and morbidity specially in cases of delayed diagnosis. Herein we will present a case report of 31 years old Saudi male who was involved in motor vehicle accident with a delayed diagnosis of pancreatic injury associated with other multiple injuries. He was diagnosed late on 12th day of admission during laparotomy where a missed high-grade pancreatic fracture at the neck of pancreas, massive pancreatic ascites and extensive pancreatic necrosis was found. Ope
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21

Ozato-Sakurai, Nami, Akikazu Fujita, and Toyoshi Fujimoto. "The Distribution of Phosphatidylinositol 4,5-Bisphosphate in Acinar Cells of Rat Pancreas Revealed with the Freeze-Fracture Replica Labeling Method." PLoS ONE 6, no. 8 (2011): e23567. http://dx.doi.org/10.1371/journal.pone.0023567.

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Nikkel, Lucas E., Sapna P. Iyer, Sumit Mohan, et al. "Pancreas–kidney transplantation is associated with reduced fracture risk compared with kidney-alone transplantation in men with type 1 diabetes." Kidney International 83, no. 3 (2013): 471–78. http://dx.doi.org/10.1038/ki.2012.430.

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23

Messaoudi, N., N. Bouichrat, M. Karrou, et al. "Bilateral Lipoadenoma of the Adrenal Glands and Humeral Brown Tumor: An Unusual Association." Case Reports in Endocrinology 2021 (August 27, 2021): 1–6. http://dx.doi.org/10.1155/2021/4870493.

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Adrenal adenolipomas are rare lipomatous adrenal tumors that can be either functional or not. Only 7 cases have been reported in the English literature so far. However, brown tumors are benign, rare, historical lesions, with histological similarity to giant tumors that can be encountered in 1% of all primary hyperparathyroidism cases. We report the case of an unusual association of bilateral lipoadenoma of the adrenal glands and humeral brown tumor in a 35-year-old patient. He presented to the emergency department with a pathological fracture of the left humerus secondary to a brown tumor. The
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24

In't Veld, P. A., D. G. Pipeleers, and W. Gepts. "Glucose alters configuration of gap junctions between pancreatic islet cells." American Journal of Physiology-Cell Physiology 251, no. 2 (1986): C191—C196. http://dx.doi.org/10.1152/ajpcell.1986.251.2.c191.

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In rat pancreatic islets, gap junctional subunits (GJS) occur under two different configurations, namely in linear single strands and in polygonal particle aggregates. The present freeze-fracture study demonstrates that GJS can rapidly (dis)assemble into one of these membrane specializations without changes in their total number. Isolation of the pancreatic gland and its perfusion at 2.8 mM glucose is accompanied by a decrease in polygonally packed GJS from 46 to 16%. A rise in medium glucose concentration is followed, within 10 min, by a dose-dependent increase in the percent polygonal partic
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Wang, Rui, Ya Liu, Yan Liang, et al. "Regional differences in islet amyloid deposition in the residual pancreas with new-onset diabetes secondary to pancreatic ductal adenocarcinoma." World Journal of Gastrointestinal Surgery 15, no. 8 (2023): 1703–11. http://dx.doi.org/10.4240/wjgs.v15.i8.1703.

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Tumour rupture of gastrointestinal stromal tumours (GISTs) has been considered to be a remarkable risk factor because of its unfavourable impact on the oncological outcome. Although tumour rupture has not yet been included in the current tumor-node-metastasis classification of GISTs as a prognostic factor, it may change the natural history of a low-risk GIST to a high-risk GIST. Originally, tumour rupture was defined as the spillage or fracture of a tumour into a body cavity, but recently, new definitions have been proposed. These definitions distinguished from the prognostic point of view bet
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26

JEONG, Sung Yub, Hojun LEE, and Yoonhyun LEE. "A case of hemodynamic unstable solder due to traumatic pancreas head injury with pelvic bone fracture: Staging whipple’s operation is an option?" Annals of Hepato-Biliary-Pancreatic Surgery 26, Suppl 1 (2022): S363. http://dx.doi.org/10.14701/ahbps.2022s1.ep-83.

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27

Mahendra, Ashish, Basanta Kumar Choudhury, Tamanna Sharma, Neha Bansal, Richa Bansal, and Shivangi Gupta. "Vitamin D and gastrointestinal cancer." Journal of Laboratory Physicians 10, no. 01 (2018): 001–5. http://dx.doi.org/10.4103/jlp.jlp_49_17.

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AbstractVitamin D serves as a precursor to the potent steroid hormone calcitriol, which has widespread actions throughout the body. Calcitriol regulates numerous cellular pathways that could have a role in determining cancer risk and prognosis. Low Vitamin D levels have been implicated in numerous disease processes including fracture risk, falls, cardiovascular disease, hypertension, diabetes mellitus, and cancers. Metabolite of 1, 25-dihydroxyvitamin D3 (1,25[OH]2D3) regulates numerous genes that control gut physiology and homeostasis. 1,25(OH)2D3 serves various functions such as maintaining
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28

Kitaura, Hideki, Saika Ogawa, Fumitoshi Ohori, et al. "Effects of Incretin-Related Diabetes Drugs on Bone Formation and Bone Resorption." International Journal of Molecular Sciences 22, no. 12 (2021): 6578. http://dx.doi.org/10.3390/ijms22126578.

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Patients with type 2 diabetes have an increased risk of fracture compared to the general population. Glucose absorption is accelerated by incretin hormones, which induce insulin secretion from the pancreas. The level of the incretin hormone, glucagon-like peptide-1 (GLP-1), shows an immediate postprandial increase, and the circulating level of intact GLP-1 is reduced rapidly by dipeptidyl peptidase-4 (DPP-4)-mediated inactivation. Therefore, GLP-1 receptor agonists and DPP-4 inhibitors are effective in the treatment of type 2 diabetes. However, these incretin-related diabetic agents have been
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29

Jung, Jongyun, and Qing Wu. "Identification of bone mineral density associated genes with shared genetic architectures across multiple tissues: Functional insights for EPDR1, PKDCC, and SPTBN1." PLOS ONE 19, no. 4 (2024): e0300535. http://dx.doi.org/10.1371/journal.pone.0300535.

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Recent studies suggest a shared genetic architecture between muscle and bone, yet the underlying molecular mechanisms remain elusive. This study aims to identify the functionally annotated genes with shared genetic architecture between muscle and bone using the most up-to-date genome-wide association study (GWAS) summary statistics from bone mineral density (BMD) and fracture-related genetic variants. We employed an advanced statistical functional mapping method to investigate shared genetic architecture between muscle and bone, focusing on genes highly expressed in muscle tissue. Our analysis
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30

Ali, Md Yousuf, Alamgir Kabir, Shahad Saif Khandker, et al. "Assessment of Toxicity and Therapeutic Effects of Goose Bone in a Rat Model." Journal of Chemistry 2019 (October 29, 2019): 1–10. http://dx.doi.org/10.1155/2019/1943601.

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Goose bone is traditionally used in the treatment of many ailments including in bone fracture. The aim of the present study was to evaluate the subacute toxicity of goose bone in a rat model by investigating some hematological and biochemical parameters in rats. Subsequently, a histopathological study was performed to confirm the presence of pathological lesions in the rat’s vital organs including the liver, kidney, heart, brain, pancreas, lung, spleen, and stomach. Adult Wistar rats were divided into four groups (n = 8) and were orally administrated with three doses (30, 60, and 120 mg/kg) of
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31

Taftachi, Farrokh, Leyla Abdolkarimi, Maryam Ameri, Azadeh Memarian, Alireza Behzadi, and Hooman Bakhshandeh. "Association Between Adrenal Hematoma and Mortality in Pediatric Multiple Blunt Traumas: An Autopsy Evaluation." Global Journal of Health Science 9, no. 4 (2016): 70. http://dx.doi.org/10.5539/gjhs.v9n4p70.

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<p>Adrenal hematoma is a common hidden catastrophic complication in pediatric victims of multiple blunt traumas. Adrenal hematoma has no obvious symptoms and may not be detected by diagnostic methods such as magnetic resonance imaging, computed tomography scan, and sonography; consequently, this complication may be neglected in children with multiple blunt traumas and cause death through sudden adrenal crisis.</p><p>The current study was conducted on 55 dead children (<13 y) and 110 matured youths (13–17 y) who died in consequence of multiple blunt traumas, comprising
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32

Hamann, Christine, Ann-Kristin Picke, Graeme M. Campbell, et al. "Effects of Parathyroid Hormone on Bone Mass, Bone Strength, and Bone Regeneration in Male Rats With Type 2 Diabetes Mellitus." Endocrinology 155, no. 4 (2014): 1197–206. http://dx.doi.org/10.1210/en.2013-1960.

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Type 2 diabetes mellitus (T2DM) is associated with increased skeletal fragility and impaired fracture healing. Intermittent PTH therapy increases bone strength; however, its skeletal and metabolic effects in diabetes are unclear. We assessed whether PTH improves skeletal and metabolic function in rats with T2DM. Subcritical femoral defects were created in diabetic fa/fa and nondiabetic +/+ Zucker Diabetic Fatty (ZDF) rats and internally stabilized. Vehicle or 75 μg/kg/d PTH(1–84) was sc administered over 12 weeks. Skeletal effects were evaluated by μCT, biomechanical testing, histomorphometry,
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33

Jayagandhi S, Verma S, Hussain Saheb S, Ambrose M, Shishir S, and M, Ramdas A. "Hunchback with “S” Shape Spine: Cadaveric Case series." International Journal of Anatomy and Research 10, no. 3 (2022): 8439–44. http://dx.doi.org/10.16965/ijar.2022.183.

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Introduction: Kyphosis is a sharp posterior angulation due to localized collapse or wedging of one or more vertebrae and scoliosis is the lateral curvature of the spine. These may occur due to a congenital defect, fracture, and sometimes pathological or spinal tuberculosis. Materials and Methods: During routine cadaver dissection, four cases of kyphoscoliosis were identified. In the first case, a protrusion on the posterior surface of the trunk of the cadaver at L1 level was observed in a 60-year-old male. The lungs were collapsed and adherent with the pleura and thoracic wall. The posterior w
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S, Verma, Aggarwal S, Verma A, et al. "Evaluation of clinical and radiological correlation in blunt trauma abdomen." Journal of Medical and Scientific Research 12, no. 1 (2024): 45–48. http://dx.doi.org/10.17727/jmsr.2024/12-8.

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Background: Abdominal trauma is commonly encountered injury caused mainly due to road traffic accidents (RTA). The research aimed to study the cases of abdominal trauma, its different modes of presentation and correlation of radiological and clinical findings with operative findings in these patients. Material and methods: An observational study was conducted in a tertiary care institute. Hemodynamic instability and finding of shattered solid viscera on imaging and/or other injury requiring exploration were the criteria for surgical intervention. Radiological findings were then compared with t
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35

Arous, Tania, Sara Gianfagna, Jaydira Del Rivero, and Inga Harbuz-Miller. "Tissue Is the Issue - A Case of Malignant Insulinoma." Journal of the Endocrine Society 5, Supplement_1 (2021): A1042. http://dx.doi.org/10.1210/jendso/bvab048.2133.

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Abstract Introduction: Insulinomas are rare, functioning pancreatic neuroendocrine tumors, predominantly benign (90%). Most are sporadic, but they can occur as part of inherited disorders. Large size insulinomas are more likely to be malignant. 68Gallium (Ga)-DOTATATE scan is an essential tool in diagnosis and treatment of pancreatic neuroendocrine tumors. However, tissue diagnosis is the ultimate prognosis predictor and treatment guide. Clinical Case: An 80-year-old man presented with left ankle fracture after a syncopal episode. In the past several months he reported multiple episodes of lig
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López, Alfonso, and Shawn McKenna. "Bovine pancreatolithiasis: case report and review of the literature." Journal of Veterinary Diagnostic Investigation 30, no. 5 (2018): 760–62. http://dx.doi.org/10.1177/1040638718780190.

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An 8-y-old lactating Holstein cow was presented to the herd veterinarian with a history of acute ataxia, and because of poor prognosis, the animal was euthanized and submitted for postmortem examination. A lumbar vertebra was incompletely fractured and had an adjacent subdural hematoma. The pancreas had a hard texture with exaggerated nodular appearance, and on cut surface, the pancreatic ducts appeared fibrotic and contained scores of round-to-faceted pancreatoliths of 0.5–2.0 mm diameter. These calculi extended from the major ducts to the pancreatic duct, sphincter, and into the duodenal lum
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Sarkar, Reith R., Katherine E. Fero, Daniel M. Seible, Neil Panjwani, Rayna K. Matsuno, and James D. Murphy. "A Population-Based Study of Morbidity After Pancreatic Cancer Diagnosis." Journal of the National Comprehensive Cancer Network 17, no. 5 (2019): 432–40. http://dx.doi.org/10.6004/jnccn.2018.7111.

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Background: Pancreatic cancer is an aggressive disease characterized by early and relentless tumor spread, thus leading healthcare providers to consider it a “distant disease.” However, local pancreatic tumor progression can lead to substantial morbidity. This study defines the long-term morbidity from local and nonlocal disease progression in a large population-based cohort. Methods: A total of 21,500 Medicare beneficiaries diagnosed with pancreatic cancer in 2000 through 2011 were identified. Hospitalizations were attributed to complications of either local disease (eg, biliary disorder, upp
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Sawicki, Rafał, Samuel Mazur, Piotr Kotarski, Katarzyna Sklinda, and Jerzy Walecki. "A non-cardiac applications of T1-mapping." Wiedza Medyczna 3, no. 2 (2021): 10–14. http://dx.doi.org/10.36553/wm.87.

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T1-mapping has proven to be a valuable tool in cardiac imaging. While mainly used in cardiac MRI, it is investigated for usage and application of T1-mapping to imaging of other organs and systems, including abdominal imaging, musculoskeletal imaging or neuroradiology, resulting in potential new prospects for medical imaging. T1-mapping provides numerical data on an inherent, physical property of imaged tissue – enabling quantitative and comparative assessment of tissue characterization f.ex. fibrosis, amyloid contents, fatty transformation, myelinization or contrast enhancement as well as lesi
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39

Sarkar, Reith, Katherine Elaine Fero, Neil Panjwani, Rayna Matsuno, and James Don Murphy. "A population-based study of morbidity after pancreatic cancer diagnosis." Journal of Clinical Oncology 36, no. 4_suppl (2018): 236. http://dx.doi.org/10.1200/jco.2018.36.4_suppl.236.

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236 Background: Pancreatic cancer is characterized by early and relentless tumor spread. This leads healthcare providers to consider pancreatic cancer a “distant disease.” However, local tumor progression within the pancreas can lead to substantial morbidity. This study defines the long-term morbidity from local and non-local disease progression in a large population-based cohort. Methods: We identified 21,500 Medicare beneficiaries diagnosed with pancreatic cancer between 2000-2011 in the Survival, Epidemiology and End Results database. Hospitalizations identified from Medicare claims were at
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Styczynska-Soczka, K., W. Cawley, K. Samuel, J. Campbell, A. Amin, and A. Hall. "DEVELOPMENT OF A HUMAN EX VIVO FEMORAL HEAD MODEL TO ASSESS MESENCHYMAL STROMAL CELL REGENERATION OF ARTICULAR CARTILAGE." Orthopaedic Proceedings 105-B, SUPP_8 (2023): 118. http://dx.doi.org/10.1302/1358-992x.2023.8.118.

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Articular cartilage has poor repair potential and the tissue formed is mechanically incompetent. Mesenchymal stromal cells (MSCs) show chondrogenic properties and the ability to re-grow cartilage, however a viable human model for testing cartilage regeneration and repair is lacking. Here, we describe an ex vivo pre-clinical femoral head model for studying human cartilage repair using MSCs.Human femoral heads (FHs) were obtained following femoral neck fracture with ethical permission/patient consent and full-depth cartilage wells made using a 3mm biopsy punch. Pancreas-derived mesenchymal strom
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Camacho, Yudi, Yusra Jamal, Erica Brutsaert, and Gayotri Goswami. "ODP026 An Incidental Giant Normotensive Pheochromcytoma with Elevated Metanephrines demonstrated no evidence of hypertensive crisis during a major surgery." Journal of the Endocrine Society 6, Supplement_1 (2022): A52—A53. http://dx.doi.org/10.1210/jendso/bvac150.109.

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Abstract A 48-year-old Caucasian male with no known past medical history admitted to our hospital following MVA resulting in acute severely comminuted displaced fracture of the left femur and tibia. On admission, the patient was in severe pain. His vitals were significant for elevated blood pressure (BP) of 137/100 and pulse rate of 161 per minute, which resolved soon after pain medications and splint placement. On review of systems, he denied episodic spells of headaches, palpitations, pallor, tremors, anxiety, abdominal pain, or diaphoresis. He denied any family history of endocrine disorder
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Hershman, M. J., R. Maxwell, and R. D. Rosin. "Pancreatic Pseudocyst Due to Fractured Pancreas." Journal of the Royal Society of Medicine 85, no. 5 (1992): 295–96. http://dx.doi.org/10.1177/014107689208500518.

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Dubois, J., J. Porcheron, M. Lacroix, and N. Menaoui. "Fracture isolée de l’isthme du pancréas." Annales de Chirurgie 126, no. 9 (2001): 863–68. http://dx.doi.org/10.1016/s0003-3944(01)00618-6.

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Bruges, Paula, Ian Schonman, Marianna Zahurak, et al. "Bone metastases and skeletal related events in patients with gastrointestinal neuroendocrine tumors." Journal of Clinical Oncology 42, no. 16_suppl (2024): 4126. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.4126.

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4126 Background: The clinical implications and management of bone metastases in patients (pts) with gastrointestinal neuroendocrine tumors (GI-NETs) is poorly characterized. In this study we investigated the frequency of bone metastases and skeletal-related events (SRE) in pts with GI-NETs. Methods: Retrospective review of ptswith GI-NETs seen at our institution between 2010-2022. We collected clinicopathologic data including tumor primary site, tumor differentiation, grade using Ki-67 labeling index (G1, G2, or G3), time of diagnosis of metastatic GI-NET, and development of bone metastases (s
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Zerbib, P., A. Brams, and J. P. Chambon. "Les fractures isthmiques du pancréas." Annales de Chirurgie 126, no. 5 (2001): 421–26. http://dx.doi.org/10.1016/s0003-3944(01)00527-2.

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Seo, Dong-Kyo, Ho Seong Lee, Jungu Park, Chang Hyun Ryu, Duck Jong Han, and Sang Gyo Seo. "Diabetic Foot Complications Despite Successful Pancreas Transplantation." Foot & Ankle International 38, no. 6 (2017): 656–61. http://dx.doi.org/10.1177/1071100717696246.

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Background: It is known that successful pancreas transplantation enables patients with diabetes to maintain a normal glucose level without insulin and reduces diabetes-related complications. However, we have little information about the foot-specific morbidity in patients who have undergone successful pancreas transplantation. The purpose of this study was to investigate the prevalence and predisposing factors for foot complications after successful pancreas transplantation. Methods: This retrospective study included 218 patients (91 males, 127 females) who had undergone pancreas transplantati
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Torregrosa, José-Vicente, Ana Sánchez-Escuredo, David Fuster, et al. "DXA Variations and Fractures After Simultaneous Pancreas-Renal Transplantation." Clinical Nuclear Medicine 40, no. 4 (2015): e232-e235. http://dx.doi.org/10.1097/rlu.0000000000000643.

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Cohen, Seth A., Frederick D. Rutkovsky, Jerome H. Siegel, and Franklin E. Kasmin. "Endoscopic Stenting and Sphincterotomy of the Minor Papilla in Symptomatic Pancreas Divisum: Results and Complications." Diagnostic and Therapeutic Endoscopy 1, no. 3 (1995): 131–39. http://dx.doi.org/10.1155/dte.1.131.

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Pancreas divisum has been postulated as a cause of acute pancreatitis and a chronic pain syndrome in a small subgroup of patients and can be treated with endoscopic dorsal pancreatic duct stent placement and minor papilla sphincterotomy. Twenty patients (9 with at least one attack of idiopathic pancreatitis, and 11 with severe pancreatic-type pain) were treated endoscopically. Dorsal duct stents were placed in 19 patients with subsequent needle knife sphincterotomy of the minor papilla over the stent. Clinical response was judged by comparison of symptoms (using a 0-to-l0 scale and the patient
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Prete, Francesco Paolo, Giovanna Di Meo, Patrizia Liguori, et al. "Modified “Blumgart-Type” Suture for Wirsung-Pancreaticogastrostomy: Technique and Results of a Pilot Study." European Surgical Research 62, no. 2 (2021): 105–14. http://dx.doi.org/10.1159/000515987.

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<b><i>Introduction:</i></b> Postoperative pancreatic fistula (POPF) represents the principal determinant of morbidity and mortality after pancreaticoduodenectomy. Since 1994 we have been performing pancreaticogastrostomy with duct-to-mucosa anastomosis (Wirsung-pancreaticogastric anastomosis [WPGA]), but postoperative morbidity, although limited, was still a concern. An original pancreas-transfixing suture technique, named “Blumgart’s anastomosis” (BA), has shown efficacy at reducing fistula rates from pancreaticojejunostomy. Few cohort studies have shown that WPGA with
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Smets, Y. "Low bone mass and high incidence of fractures after successful simultaneous pancreas-kidney transplantation." Nephrology Dialysis Transplantation 13, no. 5 (1998): 1250–55. http://dx.doi.org/10.1093/ndt/13.5.1250.

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