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1

Aishatu, Omoragbon, Emmanuel Gabriel Olusegun, Muftau Shabi Olabode, et al. "Papanicoleau Smear Usage and Prevalence of Premalignant Cervical Lesion among Women Living with HIV Attending a Federal Teaching Hospital in South-West Nigeria: A Comparative Study." Journal of Cancer and Tumor International 5, no. 4 (2017): 1–9. https://doi.org/10.9734/JCTI/2017/33231.

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<strong>Aim:</strong> Cancer of the cervix is the third most common cancer among women worldwide, and in Nigeria it is the second most common female cancer. Infection with the Human immunodeficiency virus (HIV) is associated with an increased risk of prevalent, incident and persistent squamous intraepithelial lesions (SILs) of the cervix. The aim was to determine the level of awareness of cervical cancer screening test and the development of premalignant cervical lesions among HIV positive women. <strong>Study Design:</strong> A Hospital based comparative cross-sectional study. <strong>Place a
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Omoragbon, Aishatu, Olusegun Gabriel, Olabode Shabi, et al. "Papanicoleau Smear Usage and Prevalence of Premalignant Cervical Lesion among Women Living with HIV Attending a Federal Teaching Hospital in South-West Nigeria: A Comparative Study." Journal of Cancer and Tumor International 5, no. 4 (2017): 1–9. http://dx.doi.org/10.9734/jcti/2017/33231.

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Manipriya, R., K. Deepa, and C. L. Chitra. "Significance of papanicolau smear in STD clinic of a tertiary care teaching hospital." International Journal of Research in Dermatology 4, no. 3 (2018): 381. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20183162.

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&lt;p class="abstract"&gt;&lt;strong&gt;Background:&lt;/strong&gt; HPV infection is one of the common STI’s in females with a majority of patients being asymptomatic and sub-clinical. It is often associated with STI’s and can be a great source of morbidity to patients. Pap smear is one of the effective screening tests for genital HPV infections and HPV induced neoplasia. The aim of the study was to assess the epithelial abnormalities and associated STI’s in study group using Pap smear.&lt;/p&gt;&lt;p class="abstract"&gt;&lt;strong&gt;Methods:&lt;/strong&gt; 500 female patients above the age of
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Videla, Sebastián, Antoni Tarrats, Arelly Ornelas, et al. "Incidence of cervical high-grade squamous intraepithelial lesions in HIV-1-infected women with no history of cervical pathology: up to 17 years of follow-up." International Journal of STD & AIDS 30, no. 1 (2018): 56–63. http://dx.doi.org/10.1177/0956462418792653.

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Currently, Papanicolaou smears are proposed at three-year intervals for cervical screening to all women living with HIV. The aim of this retrospective cohort study was to provide data on the incidence of cervical high-grade squamous intraepithelial lesions (HSIL) in cervical smear confirmed by histology in HIV-1-infected women (two consecutive normal Papanicolaou smears at baseline) after a long-term follow-up. Sixty-seven women (recruited between March 1999 and January 2003) were analyzed. The median period of follow-up was 13.2 years (range: 7.4–17.1 years) with a total of 583 Papanicolaou s
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Sari, Indah, Bastian Darwin, and Try Era Realita. "ANALISA METODE FIKSASI KERING MENGGUNAKAN GIEMSA DAN FIKSASI BASAH MENGGUNAKAN PAPANICOLAOU PADA PEMERIKSAAN PAP SMEAR." Masker Medika 9, no. 1 (2021): 446–54. http://dx.doi.org/10.52523/maskermedika.v9i1.456.

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Kanker serviks adalah penyakit yang ditandai dengan pertumbuhan sel yang tidak terkontrol dan penyebaran sel abnormal yang terjadi di serviks. World Health Organization (WHO) menjelaskan bahwa kanker serviks merupakan penyebab kematian nomor dua pada perempuan dari seluruh penyakit kanker yang ada. Pap smear merupakan pemeriksaan yang dilakukan untuk mendeteksi kanker serviks. Pemeriksaan pap smear menggunakan bahan pemeriksaan swab vagina yang harus dilakukan fiksasi basah sebelum pewarnaan papanicolaou dan fiksasi kering sebelum pewarnaan giemsa. Penelitian bertujuan untuk menganalisa metode
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Kamble, Shilpa A., Vijay D. Dombale, and Forum Shah. "Merits and pitfalls of normal saline rehydrated air-dried cervical smears over conventional wet.fixed PAP smears." Indian Journal of Pathology and Microbiology 65, no. 1 (2022): 100–104. http://dx.doi.org/10.4103/ijpm.ijpm_1214_20.

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Background: Cervical Papanicolaou (PAP) smear is the simplest, minimal invasive, and excellent screening method to reduce the female morbidity and mortality due to cervical carcinoma. Immediate alcohol fixation of the cervical smears is required to preserve nuclear details, delay in alcohol fixation leads to air drying artifacts. Rehydrating of the air-dried cervical pap smear with normal saline can help to overcome these artifacts and also have its own advantages. Aims: This study was design to evaluate the effects, merits and pitfalls of normal saline Rehydrated Air-Dried Cervical PAP Smears
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Mohammed, Isra'a, and Ezedeen Baha'aedeen. "Impact of papanicolaou smear upon physical and psychosocial aspects of women's health." Iraqi National Journal of Nursing Specialties 25, no. 3 (2018): 107–19. http://dx.doi.org/10.58897/injns.v25i3.148.

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Objectives: To identify the impact of Pap smear upon physical and psychological and social aspects of women'shealth.Methodology: A purposive sample of (71) women. The data were collected through the utilization of thedeveloped questionnaire which consists of four major parts: 1. demographic 2.Physical domain 3. Psychologicaldomain 4. social domain and by means of interview technique with the women who were individually interviewedin the Baghdad Teaching Hospital/ the Consultant Clinic, Teaching Laboratories/ Medical City, AL-ElwyiahMaternity Hospital . The data collection process has been perf
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Rahnama, P., S. Faghihzadeh, and S. Ziaei. "Effect of the sampling sequence on the quality of Papanicolaou smear." International Journal of Gynecologic Cancer 15, no. 1 (2005): 66–69. http://dx.doi.org/10.1136/ijgc-00009577-200501000-00011.

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The aim of the study was to determine whether the order of cell collection (ie, obtaining either endocervical first or ectocervical cells first) has an effect on the quality of the Papanicolaou smear. 1129 smears were obtained using an Ayre spatula and an endocervical brush. In 564 cases, the endocervical brush was used first, and in 565 cases, the spatula was used first. The number of smears obscured by blood, the smears without endocervical component, and the smears with poor fixation were compared between the two groups. More smears were partially obscured by blood when brush was used first
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Khan, Abiha Ahmad, Syeda Aamena Naaz, Diwan I. Khan, and M. Anas M. Anas. "Papanicolaou Smear screening in Aligarh: A Review of the Cases." Biosciences Biotechnology Research Asia 20, no. 1 (2023): 29–33. http://dx.doi.org/10.13005/bbra/3065.

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ABSTRACT: Cervical cancer is the second most common cancer after breast cancer. The risk factors associated with this dreaded yet preventable cancer is age at sexual debut, parity, multiple sexual partners, use of contraceptives and smoking etc. Fortunately, the cervical cancer are preventable because of the early detection of precancerous lesions. This is made possible by the screening procedures routinely in practice such as Pap smear, visual inspection and HPV. Methodology: The study was conducted to evaluate cervical cytological abnormalities, through pap smear reported as inflammatory les
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Pudasaini, Sujata, Rakesh Pathak, Kricha Pande, and Shraddha Koirala. "Comparison of Ultrafast Papanicolaou stain with standard Papanicolaou stain for cervical smear." Journal of Pathology of Nepal 8, no. 2 (2018): 1378–83. http://dx.doi.org/10.3126/jpn.v8i2.20890.

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Background: After the first evolution of Papanicolaou smear, it has been successfully used to screen cervical cancer. With modifications in the staining method of Pap stain, the lesser staining time and unequivocal cell morphology has been achieved by Ultrafast Papanicolaou stain. The aim of this study is to compare the UFP stain and SP stain in cervical pap smears on the basis of background, cell morphology, nuclear details and overall staining.Materials and methods: This is a prospective hospital based study conducted in a tertiary hospital, Nepal Medical College over a period of six months
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Gwavu, Zintle, Daphne Murray, and Uchenna Benedine Okafor. "Perception of Women’s Knowledge of and Attitudes towards Cervical Cancer and Papanicolaou Smear Screenings: A Qualitative Study in South Africa." Healthcare 11, no. 14 (2023): 2089. http://dx.doi.org/10.3390/healthcare11142089.

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Background: Cervical cancer is the most common form of cancer worldwide. Consequently, it is crucial that women are encouraged to undergo interventions early via Papanicolaou (Pap) smear screenings to improve their health. In light of this, this study explored the knowledge of and attitudes towards cervical cancer and Papanicolaou (Pap) smear screenings among women in the Caleb Motshabi district, South Africa. Four focus group discussions were carried out among 19 women. The interviews/discussion were audio-recorded and transcribed verbatim and then analysed thematically. In this regard, seven
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Adewale, Oyenike Musiliu, Avwioro Godwin Ovie, Iyare Godfrey Innocent, et al. "Concordance between PAP smears and P53 expression in women with cervical abnormalities in Osogbo, Southwest, Nigeria." Sokoto Journal of Medical Laboratory Science 9, no. 3 (2024): 81–92. https://doi.org/10.4314/sokjmls.v9i3.8.

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Cervical cancer screening, involving Papanicolaou (PAP) smear and assessment of p53 expression, is crucial for early detection and prevention of cervical cancer. The aim is to evaluate the concordance between Papanicolaou (PAP) smears and P53 expression in detecting cervical abnormalities in Osogbo women southwest, Nigeria. This cross-sectional study involved 221 women aged 18–65 attending Uniosun teaching hospital for cervical screening between January 2023 and December 2023. Cervical cytology was performed using PAP smears, and P53 expression was assessed through immunohistochemistry of the
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Kahn, Jessica A., Victoria Chiou, Jennifer D. Allen, Elizabeth Goodman, Sally E. Perlman, and S. Jean Emans. "Beliefs About Papanicolaou Smears and Compliance With Papanicolaou Smear Follow-up in Adolescents." Archives of Pediatrics & Adolescent Medicine 153, no. 10 (1999): 1046. http://dx.doi.org/10.1001/archpedi.153.10.1046.

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E., Nandhini, Sasikala R., and Varadharaja Perumal. "Comparison of cervical acid phosphatase papanicolaou stain and standard papanicolaou stain as a screening tool for cancer cervix." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 11, no. 12 (2022): 3300. http://dx.doi.org/10.18203/2320-1770.ijrcog20223120.

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Background: Carcinoma cervix is the second most common cancer in women (18%). Cervical smear by routine Papanicolaou (Pap) smear screening has significant rates of false-positive and false-negative results. To minimise this, we compare the efficacy of cervical acid phosphatase-papanicolaou (CAP-Pap) smear with conventional Pap smear in detecting premalignant lesions of cervix. The red-colored granules (enzyme coated abnormal cells) that are clearly detected, CAP-Pap positive aids in the quick and early diagnosis of aberrant cells, which speeds up the screening procedureMethods: The present obs
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Mitra, Nishant, Vivek Singh, Anamika Singh Rawat, Seema Awasthi, Ankita Mittal, and Shyamoli Dutta. "Comparative Study of Modified Ultrafast Papanicolaou and Standard Papanicolaou Staining Technique for the Assessment of Cervical Smears." Acta Medica International 11, no. 2 (2024): 137–42. http://dx.doi.org/10.4103/amit.amit_53_24.

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Introduction: Cervical invasive carcinoma is one of the most frequent cancers in the world, and it can be prevented with screening. The papanicolaou (Pap) smear is the most common screening procedure. Pap staining, as it is now done, is costly, requires a large amount of alcohol, and takes a long time. Materials and Methods: A total of 170 patients were recruited. One hundred and sixty-six patients, considering eligibility criteria, undergoing Pap smear test. Eligibility criteria: Age: 18–49 years females, who did not have a total hysterectomy done, who consented to participate in the study. E
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Michail, Georgios, Georgios Androutsopoulos, Apostolos Georgantis, Georgios Adonakis, and Georgios Decavalas. "Abnormal cytologic findings during pregnancy." Hel J Obst Gynecol 14, no. 2 (2015): 39–48. https://doi.org/10.5281/zenodo.6013062.

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Our aim was the illustration of the controversies that occur during pregnancy related to the mode of obtaining and interpreting a cervical smear, specific colposcopic features, as well as the approach of diagnosing, following-up and treatment, based on the findings of the Papanicolaou smear. A review of the literature as well as the updated American Society of Colposcopy and Cervical Pathology (ASCCP) guidelines on the management of abnormal Papanicolaou smears known as 2012 Bethesda Consensus Guidelines, was undertaken. The results of the abnormal smears were categorized according to their se
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&NA;, &NA;. "Papanicolaou Smear." Nurse Practitioner 19, no. 12 (1994): 74–77. http://dx.doi.org/10.1097/00006205-199412000-00014.

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Shrader, Sydney, Enrique Hernandez, and John Gaughan. "Is There a Seasonal Difference in the Detection of Trichomonas vaginalis by Cervical Cytology?" Scientific World JOURNAL 3 (2003): 45–50. http://dx.doi.org/10.1100/tsw.2003.10.

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This objective of our study was to determine the prevalence of a Trichomonas vaginalis diagnosis in routine Papanicolaou smears and whether it is seasonal. We reviewed the diagnosis rendered for 93,681 Papanicolaou smears evaluated at a medical school hospital laboratory between 1992 and 1997. The occurrence of a diagnosis of T. vaginalis was analyzed by year, by quarter, and by month using a generalized linear regression model. The prevalence of a T. vaginalis diagnosis during the 6-year study period was 3.1%. The between-month and between-quarter comparisons of prevalence were not statistica
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Pande, Milind Dinkarrao, Kalyani Deshmukh, and Apoorva Pande. "Detection of Abnormal Cervical Epithelial Lesions by Papanicolaou Smear: A Retrospective Study." Journal of Datta Meghe Institute of Medical Sciences University 20, no. 2 (2025): 313–17. https://doi.org/10.4103/jdmimsu.jdmimsu_846_24.

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Abstract Introduction: A substantial portion of both mortality and morbidity is attributed to cervical cancer, which is the second most frequent malignancy in women. Papanicolaou (PAP) smear is a simple, cost-effective, and sensitive test for detecting cervical lesions. The purpose of the study was to determine the pattern of different cervical smear abnormalities and the prevalence of epithelial cell abnormalities in the study group. Materials and Methods: This was a retrospective study of 1780 cervical PAP smears screened and reported at Nagpur, India, from January 2022 to December 2022. The
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Shrestha, Sujan, Ranjan Suwal, and Shyam Nandan Gupta. "Clinicopathological Pattern of Cervical Papanicolaou (PAP) Smears: A hospital based experience." Janaki Medical College Journal of Medical Science 5, no. 2 (2018): 27–34. http://dx.doi.org/10.3126/jmcjms.v5i2.19014.

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Background and Objectives: Cervical cancer is very common type of cancer in women globally. The objective of this study was to compare the cytopathological findings of the cervical pap smears using the revised 2001 Bethesda system and to compare the cytopathological findings with the clinical features.Material and Methods: A total of 1016 pap smear sent to the Department of Cytopathology at Peoples Dental college general hospital (PDCH), Kathmandu over a period of three years were studied. Relevant history and clinical findings were retrieved for the study. The age, caste, location, gravida of
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Ashok, Sahana, and Ashok K P. "Aceto-orcein squash technique for barr body detection." RGUHS Journal of Dental Sciences 9, no. 1 (2017): 15–22. http://dx.doi.org/10.26715/rjds.9_1_3.

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BACKGROUND: Gender determination is an important aspect of forensic medicine. This can be done by identifying the presence of “Barr body”, which is the inactive ‘X’ chromosome seen in the nucleus at the nuclear membrane of a cell only in females. Sex determination can be done by other methods like polymerase chain reaction and karyotyping, which are expensive and not available in all places. Detection of Barr bodies in buccal smear is easy, cost effective and can be performed routinely with various staining methods.The aims of this study are 1) to identify Barr Bodies for gender determination.
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Borsuk, A., Anna Pryczynicz, Konstancja Ustymowicz, D. Jagodzińska, and Katarzyna Guzińska-Ustymowicz. "Analysis of cervicovaginal smears in terms of their technical quality." Progress in Health Sciences 12, no. 2 (2022): 56–61. http://dx.doi.org/10.5604/01.3001.0016.1742.

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Introduction: The aim of this study was to analyze the technical evaluation of cervicovaginal smears as well as the correlation of the technical quality of the smear with the patient’s age. Materials and methods: The study included a group of 43,696 women who underwent exfoliative cytology. The smears were stained according to the Papanicolaou method and then underwent cytological evaluation based on the Bethesda system. Results: The technical quality of the cytology smears was found to be satisfactory (AI) in 80.6% of cases, acceptable for cytological evaluation (AII) in 19% mainly as a resul
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Ahmed, Hussain Gadelkarim, Ali Mahmmoud Edris, Eneel Ahmed Mohmed, and Mohammed Omer M. Hussein. "Value of Centrifugated Liquid-Based Cytology by Papanicolaou and May-Grünwald in Oral Epithelial Cells." Rare Tumors 1, no. 1 (2009): 9–11. http://dx.doi.org/10.4081/rt.2009.e12.

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For many years, liquid-based cytology (LBC) has been developed for cervical cancer screening and not oral cancer, as it requires automated devices. The aim of this study was to compare the utility of centrifugated CLBC preparation with that of direct preparation in oral lesions, by Papanicolaou (Pap) and May Grünwald-Giemsa's (MGG) methods. A total of 100 consecutive cases of oral lesions were investigated. We compared the results obtained by the CLBC performed by cytocentrifugation with those obtained by direct smear applying Pap and MGG methods. The comparison between CLBC and direct smears
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Lai, Chiung-Ru, Chih-Yi Hsu, Jen-Fan Hang, and Anna Fen-Yau Li. "The Diagnostic Value of Routine Papanicolaou Smears for Detecting Endometrial Cancers: An Update." Acta Cytologica 59, no. 4 (2015): 315–18. http://dx.doi.org/10.1159/000438975.

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Objective: The presence of degenerative endometrial debris and abnormal endometrial cells is considered to be the hint for endometrial pathology. The purpose of this study was to evaluate the efficacy of Papanicolaou (Pap) smears in detecting endometrial cancers. Study Design: There were 146 cases of endometrial cancer diagnosed at our institute in 2000-2002 and 271 in 2010-2012. Among them, 57 and 95 relevant reports of Pap smears 6 months prior to the histology diagnosis were retrieved for this study, respectively. In the first time period, new criteria for detecting endometrial lesions had
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Costea, Iulia Andreea Badea, Sevigean Ali, Mihaela Botnarciuc, and Lavinia Carmen Daba. "Papanicolaou Test in Women with Abnormal Bacteriologic Exam Results." ARS Medica Tomitana 28, no. 2 (2022): 48–52. http://dx.doi.org/10.2478/arsm-2022-0011.

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Abstract The normal vaginal flora is complex and includes various organisms, many of them conditioned pathogens. The vaginal microbiome is controlled by estrogens that is why a major difference it encountered between pre-menopausal and menopausal women. Bacterial vaginosis was associated with inflammatory changes on Papanicolaou (PAP) smears and chronic inflammation may eventually tead to potentially precancerous and cancerous processes of the cervix. We asses the importance of PAP test and early discovery of vaginal infections because bacterial vaginosis has been associated with inflammatory
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Wilson, Chester. "Papanicolaou smear‐tests." Medical Journal of Australia 149, no. 11-12 (1988): 720. http://dx.doi.org/10.5694/j.1326-5377.1988.tb120848.x.

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Gore, Hazel. "Papanicolaou smear‐tests." Medical Journal of Australia 149, no. 11-12 (1988): 720. http://dx.doi.org/10.5694/j.1326-5377.1988.tb120849.x.

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BALDWIN, K., and K. GOODWIN. "The papanicolaou smear." Journal of Nurse-Midwifery 30, no. 6 (1985): 327–32. http://dx.doi.org/10.1016/0091-2182(85)90170-3.

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Bansal, Sonu, Chandrakanta, Harendra Kumar, and Urvashi Verma. "Spectrum of epithelial abnormalities on papanicolaou smear in postmenopausal women." IP Archives of Cytology and Histopathology Research 6, no. 2 (2021): 97–102. http://dx.doi.org/10.18231/j.achr.2021.024.

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The Papanicolaou (Pap) smear was introduced in 1941, became the standard screening test for cervical cancer and premalignant lesions, and is being used globally. To estimate the frequency of various epithelial abnormalities on Pap smear in postmenopausal women and assess their relation with parity, clinical symptoms and per speculum findings. Prospective Pap procedure was done on 400 postmenopausal women from November 2017 to June 2019 and smears were stained and cytological interpretation was made according to the 2014 Bethesda system.Out of 97.5% satisfactory smears, 17.9%, 26.2% and 55.9% w
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Yalti, S., B. GÜRBÜZ, R. Bilgiç, Y. ÇAKAR, and S. Eren. "Evaluation of cytologic screening results of the cervix." International Journal of Gynecologic Cancer 15, no. 2 (2005): 292–94. http://dx.doi.org/10.1136/ijgc-00009577-200503000-00017.

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The aim of this study was to evaluate retrospectively cytologic screening for cancers and precancerous lesions of the cervix and to research whether biopsy is overused among women with a cytologic diagnosis of atypical squamous cells of undetermined significance (ASCUS). We examined 28 469 smears obtained over 5 years. The patients were referred when the result of the smear was abnormal for a colposcopic biopsy, endocervical curettage, or a repeat Papanicolaou smear. The results of the screening of 28 469 smears are as follows: 699 (2.45%) ASCUS, 67 (0.23%) low-grade squamous intraepithelial l
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Maharjan, Sushna, Ranjita Singh, Prabha Panthi, Nirbija Dhakal, and Sabin Ranabhat. "Liquid Based Pap Smears for Detection of Infective Organisms in a Tertiary Care Hospital." International Journal of Clinical Case Reports and Reviews 11, no. 3 (2022): 01–05. http://dx.doi.org/10.31579/2690-4861/214.

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Background: Bacterial vaginosis (BV), vulvovaginal candidiasis (VVC) and trichomonal vaginitis (TV) are the most common etiologies of infective vaginitis. The Papanicolaou (Pap) smear is a standard screening test for cervical precancerous lesions that can also be useful to identify infective organisms. This study aimed to identify the causativeorganisms for cervico-vaginal infection in liquid-based Pap smears. Methods: This study was a cross sectional study and included 370 liquid based Pap smears with infective organisms. Results: The most prevalent cervico-vaginal infection was BV, which was
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Thakur, Brijesh, Ravi Mehrotra, and Jitendra Singh Nigam. "Correlation of Various Techniques in Diagnosis of Tuberculous Lymphadenitis on Fine Needle Aspiration Cytology." Pathology Research International 2013 (September 19, 2013): 1–4. http://dx.doi.org/10.1155/2013/824620.

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Objective. To study the correlation of cytomorphological features in fine needle aspiration smears from patients suspected of having tuberculous lymphadenitis with Ziehl-Neelsen staining (ZN), auramine-rhodamine staining (ARS), and autofluorescence (AF). Methods. A total of 145 lymph nodes were aspirated, 3 air-dried smears were stained with Giemsa, Ziehl-Neelsen, and auramine-rhodamine stains, and 1 smear was wet fixed for Papanicolaou staining. Needle washes were incubated in Lowenstein-Jensen medium for culture. Papanicolaou and auramine-rhodamine stained smears were examined under fluoresc
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Taghipour Zahir, Shokouh, Mahsa Yazdkhasti, Parisa Ghasempour, and Saadat Eslami. "Comparison of Three Methods, “Pap Smear, Conization and LEEP” in Women with Abnormal Pap Smear: A Ten-Year Retrospective Analytical Study." Eurasian Journal of Family Medicine 12, no. 4 (2023): 214–20. http://dx.doi.org/10.33880/ejfm.2023120405.

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Aim: Considering that many cases of abnormal pap smears are reported, which lead to more aggressive procedures such as colposcopy and cervical Loop Electrosurgical Excision Procedure conization, therefore, we tried to investigate the results of conization and compare them with the results of pap smears, so that perhaps more aggressive procedures can be avoided. Methods: This cross-sectional retrospective analytical study was conducted on women who underwent pap smear and cervical conization in Mortaz and Shahid Sadoughi hospitals from 2011 to 2020. All data including age, Pap smear, and coniza
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Jovic, Milena, Dane Nenadic, Zvonko Magic, et al. "Reliability of the CINtecTM p16INK4a immunocytochemical test in screening cervical precancerous lesions." Vojnosanitetski pregled 65, no. 3 (2008): 211–19. http://dx.doi.org/10.2298/vsp0803211j.

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Background/Aim. Overexpression of p16INK4a has been found to be linked with genomic integration of high-risk human papillomavirus (HPV) and the developement of precancerous cervical intraepithelial lesions. The aim of this study was to examine is there a higher positive level of correlation between grade of histological dysplasia and p16INK4a level of expression in cervical smear, compared to results of Papanicolaou test. We also examined the correlation between HPV type, p16INK4a expression and Papanicolau test results. Methods. A total of 48 women with precanceorous cervical lesions and HPV
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Poudel, Anuj, and Prahar Dahal. "Cytohistological correlation of conventional Papanicolaou smears in cervical neoplasia at a tertiary care hospital of Nepal." Journal of Pathology of Nepal 9, no. 1 (2019): 1475–79. http://dx.doi.org/10.3126/jpn.v9i1.23372.

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Background: Conventional Cervical Cytology is the most widely used cervical cancer screening test. The incidence of cervical carcinoma is incredibly high in developing countries due to lack of proper knowledge. The extensive use of cervical screening with Papanicolau smears had considerably increased the detection of precancerous and cancerous lesion of uterine cervix. Study was conducted to evaluate cytohistological correlation and to calculate concordance and discordance of Pap smear in detection of precancerous and cancerous lesions of uterine cervix.&#x0D; Materials and Methods: A total of
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Mashuri, Mashuri. "EARLY DETECTION OF CERVICAL CANCER WITH PAP SMEAR EXAMINATION WOMEN TOBACCO FARMERS IN WULUHAN DISTRICT OF JEMBER REGENCY." Jurnal Penelitian Sains dan Teknologi Indonesia 1, no. 2 (2022): 126–30. http://dx.doi.org/10.19184/jpsti.v1i2.171.

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The purpose of this study was to determine the prevalence of cervical precancerous lesions by conducting early detection of cervical cancer using Pap smear examination on tobacco farming women in Wuluhan District, Jember Regency. The design of this research is descriptive exploratory through the method of observational approach and using purposive sampling when selecting samples and found there are 52 respondents. The instrument of this study used an observation sheet for cervical cytology specimen examination with Papanicolaou staining and classification of cytological examination results bas
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de Boer, Eddy N., Nicole Corsten-Janssen, Elles Wierenga, et al. "Limitations of Semi-Automated Immunomagnetic Separation of HLA-G-Positive Trophoblasts from Papanicolaou Smears for Prenatal Genetic Diagnostics." Diagnostics 15, no. 3 (2025): 386. https://doi.org/10.3390/diagnostics15030386.

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Background: In prenatal genetic diagnostics, the detection of single-gene defects relies on chorionic villus sampling (CVS) and amniocentesis, which carry a miscarriage risk of 0.2–0.3%. To mitigate this risk, fetal trophoblasts have been isolated from a Papanicolaou smear using Trophoblast Retrieval and Isolation from the Cervix (TRIC). However, this method is labor-intensive and has been shown to be challenging to implement in clinical practice. Here, we describe our experiences in using semi-automated immunomagnetic cell sorting for isolating trophoblasts from clinically obtained Papanicola
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Krishna, Chaitra, Savitha Chandraiah, and Chandana Krishna. "Comparison of conventional Papanicolaou smear and liquid‑based cytology: a study of cervical cancer screening at a tertiary care center in Bengaluru." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 8 (2021): 3106. http://dx.doi.org/10.18203/2320-1770.ijrcog20212963.

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Background: Cervical cancer is the fourth commonest cancer affecting women worldwide and the second most common cancer in women aged 15-44 years. The Papanicolaou (Pap) smear has been the cornerstone of screening for cervical neoplasm for the last 50 years. Liquid-based cytology (LBC) was introduced in mid-1990s as an alternative technique to process cervical samples has many benefits over Pap. A new second generation technique, Liquiprep was introduced after a decade has the advantage of a much lower cost. However, the information available on second generation liquid based cytology is limite
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Okayama, Kaori, Mao Kakinuma, Saki Tajima, et al. "Optimal Papanicolaou Smear Conditions for Manual Microdissection of Single Target Cells." Microorganisms 11, no. 11 (2023): 2700. http://dx.doi.org/10.3390/microorganisms11112700.

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This study aimed to investigate the optimal conditions for Papanicolaou (Pap) smear to increase the success rate of target cell isolation through manual microdissection (MMD) and prevent cell spread. Pap smears were prepared using an HPV42-positive SurePath™ liquid-based cytology case, and 46 and 50 koilocytes were used in wet and dried Pap smears, respectively, to verify the success rate of target cell isolation using MMD based on the HPV detection rate. During MMD, the microscopic examination of both specimens revealed that cells in dried smears could be easily identified; however, cell debr
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Díaz-Rosario, Luis A., and Salim E. Kabawat. "Performance of a Fluid-Based, Thin-Layer Papanicolaou Smear Method in the Clinical Setting of an Independent Laboratory and an Outpatient Screening Population in New England." Archives of Pathology & Laboratory Medicine 123, no. 9 (1999): 817–21. http://dx.doi.org/10.5858/1999-123-0817-poafbt.

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Abstract Background.—A patented, fluid-based, thin-layer method for preparation of Papanicolaou (Pap) smears (ThinPrep Pap test) has been reported to be significantly more effective than the conventional smear invented by George Papanicolaou. We tested this position by comparing the cytologic diagnosis and specimen adequacy results obtained using the ThinPrep method with data from conventional Pap smears obtained from a similar population. Methods.—Test results of 56 339 ThinPrep specimens were compared with results from 74 756 conventional smear cases obtained from the same sources in a corre
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Macancela, Carlos, Manuel Eugenio Morocho-Cayamcela, and Oscar Chang. "Deep Reinforcement Learning for Efficient Digital Pap Smear Analysis." Computation 11, no. 12 (2023): 252. http://dx.doi.org/10.3390/computation11120252.

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In August 2020, the World Health Assembly launched a global initiative to eliminate cervical cancer by 2030, setting three primary targets. One key goal is to achieve a 70% screening coverage rate for cervical cancer, primarily relying on the precise analysis of Papanicolaou (Pap) or digital Pap smears. However, the responsibility of reviewing Pap smear samples to identify potentially cancerous cells primarily falls on pathologists—a task known to be exceptionally challenging and time-consuming. This paper proposes a solution to address the shortage of pathologists for cervical cancer screenin
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Jayaprakash, Megha, Sreenija Menon, Georgy Joy Eralil, Alok K. P., and Rajany Jose. "Cervical cytology profile by Papanicolaou smear in a rural setting in mid-Kerala." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 10 (2020): 4000. http://dx.doi.org/10.18203/2320-1770.ijrcog20204006.

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Background: With no systematic national screening programme, the rates of cervical epithelial cell abnormalities as reported by various studies range from 1.32% to 25% in India. Majority are epithelial squamous cell abnormalities that include atypical squamous cells of undetermined significance (ASCUS) and low-grade squamous intraepithelial lesion (LSIL). Worldwide incidence of adenocarcinoma and its precursors have increased over past few decades. Objectives were to study the clinical and cervical cytological profile among women attending camps in rural areas of Thrissur district of Kerala.Me
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Yasmin, Shakila, Tahira Munir, Ayesha Javaid, Khalid Fahim Yasin, and Junaid Hassan. "Comparison of diagnostic accuracy of papanicoloau (PAP) Smear and visual inspection using acetic acid (VIA) in screening of cervical carcinoma, taking biopsy as gold standard." Professional Medical Journal 27, no. 04 (2020): 863–69. http://dx.doi.org/10.29309/tpmj/2020.27.04.34.

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Study Design: Cross-sectional descriptive study. Setting: Department of Obstetrics &amp; Gynecology, Bahawal Victoria Hospital, Bahawalpur. Period: 05 August 2016 to 05 Feb 2017. Material &amp; Methods: A total of 228 suspected patients of cervical carcinoma and age of 20-50 years were included. Patients with acute cervicitis, pregnant females, h/o abnormal cytology and obvious lesion on cervix were excluded. All the patients were underwent papanicoloau (PAP) smear and visual inspection using acetic acid. The results of papanicoloau (PAP) smear and visual inspection using acetic acid (VIA) wer
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Sethy, Manas Ranjan, Jitendra Singh Nigam, Ashutosh Rath, Abhimanyu Sharma, Shailaja Prabhala, and Immanuel Pradeep. "Spectrum of cervicovaginal Pap smears in newly established tertiary care medical institute." Cytojournal 20 (August 29, 2023): 20. http://dx.doi.org/10.25259/cytojournal_8_2023.

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Objectives: We undertook this study to find out the spectrum of the cervical smear pattern along with the clinical profiles of patients who underwent cervical Papanicolaou (Pap) smear evaluation in our newly started tertiary care center. We also tried to find the possible clinical cause for unsatisfactory smears and factors for epithelial cell abnormality. Material and Methods: The present study was a retrospective observational study. Pap smears cases with their clinical findings mentioned on the requisition form and cytopathology observations were retrieved from the archives of the departmen
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Jones, W. B., and P. E. Saigo. "The "Atypical" Papanicolaou Smear." CA: A Cancer Journal for Clinicians 36, no. 4 (1986): 237–42. http://dx.doi.org/10.3322/canjclin.36.4.237.

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McIntyre-Seltman, Kathleen. "The abnormal papanicolaou smear." Medical Clinics of North America 79, no. 6 (1995): 1427–42. http://dx.doi.org/10.1016/s0025-7125(16)30009-8.

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Anjili, Kumari, Nazaneen Syed, and Pandey Vinita. "Detection of Cervical Cancer through Cytological Patterns in Papanicolaou Smears." International Journal of Pharmaceutical and Clinical Research 16, no. 5 (2024): 2774–77. https://doi.org/10.5281/zenodo.13822323.

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<strong>Background:</strong>&nbsp;A serious health concern is cervical cancer, especially in low- and middle-income nations where access to screening and HPV immunisation is restricted. Papanicolaou (Pap) smear screening is a vital tool for the early detection of cervical abnormalities, allowing for timely intervention and reduction in cancer-related mortality. Despite its effectiveness, inconsistencies in screening uptake and accessibility continue to pose significant challenges.&nbsp;<strong>Aim:</strong>&nbsp;This study aimed to explore the cytological patterns of Pap smears and assess the
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V, Vineetha. "Comparison of Conventional Papanicolaou Stain with Enviro Papanicolaou Stain in Buccal Smear." International Journal of Science and Research (IJSR) 12, no. 3 (2023): 1550–52. http://dx.doi.org/10.21275/sr23325205752.

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V, Subashini, Pratibha Ramani, Mpbrundha ., et al. "Rehydration of air dried oral smears using honey." International Journal of Dental Research 6, no. 1 (2018): 20. http://dx.doi.org/10.14419/ijdr.v6i1.8742.

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Background: Papanicolaou stains, very reliable cytological staining in diagnosis of oral carcinoma. In routine practice, 95% ethanol is used to fix the slides while preparing for Pap smears. The problems associated with pap smear such as short of supply and storage of alcohol, wet fixing of slides and transporting them to the cytology centre if the Pap smears are prepared at a peripheral centre. If an alternative method of rehydrating the air-dried oral smears is known we can overcome these problems. Until the date only few studies regarding rehydration of oral smears as a substitute for wet f
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Gupta, Ruchika, Ravi Yadav, Akhileshwar Sharda, et al. "Comparative evaluation of conventional cytology and a low-cost liquid-based cytology technique, EziPREP™, for cervicovaginal smear reporting: A split sample study." CytoJournal 16 (November 14, 2019): 22. http://dx.doi.org/10.4103/cytojournal.cytojournal_11_19.

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Background: Liquid-based cytology (LBC) for cervical cancer screening offers several advantages over conventional cytology. However, the extremely high cost of the current approved devices precludes widespread application of LBC technique in resource-constrained countries. This study aimed to evaluate the performance of an indigenous low-cost LBC technique, EziPREP™ (EP), against conventional preparations (CPs) for cervical cancer screening. Materials and Methods: A cross-sectional split-sample study with consecutive cervical sampling was conducted on 515 women attending the clinic at our inst
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