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Artykuły w czasopismach na temat „Patient-specific phantom”

Autor: Grafiati

Data publikacji: 2 czerwca 2025

Data aktualizacji: 31 lipca 2025

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Yin, Jun, Manqi Li, Guangli Dai, Hongzhao Zhou, Liang Ma, and Yixiong Zheng. "3D Printed Multi-material Medical Phantoms for Needle-tissue Interaction Modelling of Heterogeneous Structures." Journal of Bionic Engineering 18, no. 2 (2021): 346–60. http://dx.doi.org/10.1007/s42235-021-0031-1.

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AbstractThe fabrication of multi-material medical phantoms with both patient-specificity and realistic mechanical properties is of great importance for the development of surgical planning and medical training. In this work, a 3D multi-material printing system for medical phantom manufacturing was developed. Rigid and elastomeric materials are firstly combined in such application for an accurate tactile feedback. The phantom is designed with multiple layers, where silicone ink, Thermoplastic Polyurethane (TPU), and Acrylonitrile Butadiene Styrene (ABS) were chosen as printing materials for ski

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Radojcic, Đeni Smilovic, David Rajlic, Bozidar Casar, et al. "Evaluation of two-dimensional dose distributions for pre-treatment patient-specific IMRT dosimetry." Radiology and Oncology 52, no. 3 (2018): 346–52. http://dx.doi.org/10.2478/raon-2018-0019.

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Abstract Background The accuracy of dose calculation is crucial for success of the radiotherapy treatment. One of the methods that represent the current standard for patient-specific dosimetry is the evaluation of dose distributions measured with an ionization chamber array inside a homogeneous phantom using gamma method. Nevertheless, this method does not replicate the realistic conditions present when a patient is undergoing therapy. Therefore, to more accurately evaluate the treatment planning system (TPS) capabilities, gamma passing rates were examined for beams of different complexity pas

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Carbone, Marina, Rosanna Maria Viglialoro, Sara Stagnari, et al. "Design, Fabrication, and Preliminary Validation of Patient-Specific Spine Section Phantoms for Use in Training Spine Surgeons Outside the Operating Room/Theatre." Bioengineering 10, no. 12 (2023): 1345. http://dx.doi.org/10.3390/bioengineering10121345.

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Pedicle screw fixation (PSF) demands rigorous training to mitigate the risk of severe neurovascular complications arising from screw misplacement. This paper introduces a patient-specific phantom designed for PSF training, extending a portion of the learning process beyond the confines of the surgical room. Six phantoms of the thoracolumbar region were fabricated from radiological datasets, combining 3D printing and casting techniques. The phantoms were employed in three training sessions by a fifth-year resident who performed full training on all six phantoms; he/she placed a total of 57 pedi

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Wilson, Lydia J., Sara Belko, Eric Gingold, et al. "3D-Printed Organ-Realistic Phantoms to Verify Quantitative SPECT/CT Accuracy for 177Lu-PSMA-617 Treatment Planning." Pharmaceuticals 18, no. 4 (2025): 550. https://doi.org/10.3390/ph18040550.

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Background/Objectives: Accurate patient-specific dosimetry is essential for optimizing radiopharmaceutical therapy (RPT), but current tools lack validation in clinically realistic conditions. This work aimed to develop a workflow for designing and fabricating patient-derived, organ-realistic RPT phantoms and evaluate their feasibility for commissioning patient-specific RPT radioactivity quantification. Methods: We used computed tomographic (CT) and magnetic resonance (MR) imaging of representative patients, computer-aided design, and in-house 3D printing technology to design and fabricate anth

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Takahashi, Wataru, Shota Oshikawa, and Shinichiro Mori. "Real-time markerless tumour tracking with patient-specific deep learning using a personalised data generation strategy: proof of concept by phantom study." British Journal of Radiology 93, no. 1109 (2020): 20190420. http://dx.doi.org/10.1259/bjr.20190420.

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Objective: For real-time markerless tumour tracking in stereotactic lung radiotherapy, we propose a different approach which uses patient-specific deep learning (DL) using a personalised data generation strategy, avoiding the need for collection of a large patient data set. We validated our strategy with digital phantom simulation and epoxy phantom studies. Methods: We developed lung tumour tracking for radiotherapy using a convolutional neural network trained for each phantom’s lesion by using multiple digitally reconstructed radiographs (DRRs) generated from each phantom’s treatment planning

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Kollitz, Erika, Haegin Han, Chan Hyeong Kim, et al. "A patient-specific hybrid phantom for calculating radiation dose and equivalent dose to the whole body." Physics in Medicine & Biology 67, no. 3 (2022): 035005. http://dx.doi.org/10.1088/1361-6560/ac4738.

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Abstract Objective. As cancer survivorship increases, there is growing interest in minimizing the late effects of radiation therapy such as radiogenic second cancer, which may occur anywhere in the body. Assessing the risk of late effects requires knowledge of the dose distribution throughout the whole body, including regions far from the treatment field, beyond the typical anatomical extent of clinical computed tomography (CT) scans. Approach. A hybrid phantom was developed which consists of in-field patient CT images extracted from ground truth whole-body CT scans, out-of-field mesh phantoms

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Yoon, K., C. Jeong, M. Park, et al. "P03.07.B DOSIMETRIC ACCURACY OF CYBERKNIFE STEREOTACTIC RADIOSURGERY FOR BENIGN PERIOPTIC TUMOR." Neuro-Oncology 25, Supplement_2 (2023): ii37—ii38. http://dx.doi.org/10.1093/neuonc/noad137.118.

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Abstract BACKGROUND The Cyberknife (CK) SRS delivers a highly focused ablative radiation dose to tumors to effectively control tumors with minimized radiation toxicity to surrounding normal tissues. This study aimed to evaluate the dosimetric accuracy of Cyberknife (CK) for benign perioptic tumor using patient specific head phantom. METHODS Patient specific head phantoms was fabricated using a 3D-printer to be dosimetrically equivalent to actual target regions of benign perioptic tumor case treated via Cyberknife radiosurgery. Head phantom QA plan was produced using the original CK contour set

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Cagni, Elisabetta, Andrea Botti, Matteo Orlandi, et al. "Evaluating the Quality of Patient-Specific Deformable Image Registration in Adaptive Radiotherapy Using a Digitally Enhanced Head and Neck Phantom." Applied Sciences 12, no. 19 (2022): 9493. http://dx.doi.org/10.3390/app12199493.

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Despite the availability of national and international guidelines, an accurate and efficient, patient-specific, deformable image registration (DIR) validation methodology is not yet established, and several groups have found an incompatibility of the various digital phantoms with the commercial systems. To evaluate the quality of the computed tomography (CT) and on-board cone-beam CT (CBCT) DIRs, a novel methodology was developed and tested on 10 head and neck (HN) patients, using CT and CBCT anthropomorphic HN phantom images, digitally reprocessed to include the common organs at risk. Referen

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Hütter, Larissa, Patrick H. Geoghegan, Paul D. Docherty, Milad S. Lazarjan, Donald Clucas, and Mark Jermy. "Fabrication of a compliant phantom of the human aortic arch for use in Particle Image Velocimetry (PIV) experimentation." Current Directions in Biomedical Engineering 2, no. 1 (2016): 493–97. http://dx.doi.org/10.1515/cdbme-2016-0109.

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AbstractCompliant phantoms of the human aortic arch can mimic patient specific cardiovascular dysfunctions in vitro. Hence, phantoms may enable elucidation of haemodynamic disturbances caused by aortic dysfunction. This paper describes the fabrication of a thin-walled silicone phantom of the human ascending aorta and brachiocephalic artery. The model geometry was determined via a meta-analysis and modelled in SolidWorks before 3D printing. The solid model surface was smoothed and scanned with a 3D scanner. An offset outer mould was milled from Ebalta S-Model board. The final phantom indicated

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Ehler, Eric D., Brett M. Barney, Patrick D. Higgins, and Kathryn E. Dusenbery. "Patient specific 3D printed phantom for IMRT quality assurance." Physics in Medicine and Biology 59, no. 19 (2014): 5763–73. http://dx.doi.org/10.1088/0031-9155/59/19/5763.

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Pacioni, Alessia, Marina Carbone, Cinzia Freschi, Rosanna Viglialoro, Vincenzo Ferrari, and Mauro Ferrari. "Patient-specific ultrasound liver phantom: materials and fabrication method." International Journal of Computer Assisted Radiology and Surgery 10, no. 7 (2014): 1065–75. http://dx.doi.org/10.1007/s11548-014-1120-y.

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Ataei, Ali, Jelle Eikhout, Ruud G. H. van Leeuwen, Esther Tanck, and Florieke Eggermont. "The effect of variations in CT scan protocol on femoral finite element failure load assessment using phantomless calibration." PLOS ONE 17, no. 3 (2022): e0265524. http://dx.doi.org/10.1371/journal.pone.0265524.

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Recently, it was shown that fracture risk assessment in patients with femoral bone metastases using Finite Element (FE) modeling can be performed using a calibration phantom or air-fat-muscle calibration and that non-patient-specific calibration was less favorable. The purpose of this study was to investigate if phantomless calibration can be used instead of phantom calibration when different CT protocols are used. Differences in effect of CT protocols on Hounsfield units (HU), calculated bone mineral density (BMD) and FE failure loads between phantom and two methods of phantomless calibration

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Gurjar, Om Prakash, and Surendra Prasad Mishra. "A comparative study on patient specific absolute dosimetry using slab phantom, acrylic body phantom and goat head phantom." International Journal of Cancer Therapy and Oncology 3, no. 2 (2015): 3213. http://dx.doi.org/10.14319/ijcto.32.12.

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Dukov, Nikolay, Kristina Bliznakova, Nikiforos Okkalidis, Tsvetelina Teneva, Elitsa Encheva, and Zhivko Bliznakov. "Thermoplastic 3D printing technology using a single filament for producing realistic patient-derived breast models." Physics in Medicine & Biology 67, no. 4 (2022): 045008. http://dx.doi.org/10.1088/1361-6560/ac4c30.

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Abstract Objective. This work describes an approach for producing physical anthropomorphic breast phantoms from clinical patient data using three-dimensional (3D) fused-deposition modelling (FDM) printing. Approach. The source of the anthropomorphic model was a clinical Magnetic Resonance Imaging (MRI) patient image set, which was segmented slice by slice into adipose and glandular tissues, skin and tumour formations; thus obtaining a four component computational breast model. The segmented tissues were mapped to specific Hounsfield Units (HU) values, which were derived from clinical breast Co

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Sigona, Michelle K., Thomas J. Manuel, Huiwen Luo, et al. "Generating patient-specific acoustic simulations for transcranial focused ultrasound procedures based on optical tracking information." Journal of the Acoustical Society of America 152, no. 4 (2022): A155. http://dx.doi.org/10.1121/10.0015868.

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During transcranial focused ultrasound (FUS) procedures, accurate targeting is important and neuronavigation with optically tracked tools is used to estimate the free-field focal location on pre-acquired images. Offline neuronavigation systems do not typically incorporate aberrating effects of the skull known to displace and distort the focus. Here, we developed a pipeline that integrated patient-specific acoustic simulations informed by transformations from optically tracked FUS procedures as a tool to evaluate transcranial pressure fields and demonstrated its use in three FUS scenarios: magn

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Venturi, David, Neil Glossop, and Reto Bale. "Patient-specific templates for image-guided intervention - a phantom study." Minimally Invasive Therapy & Allied Technologies 29, no. 5 (2019): 251–60. http://dx.doi.org/10.1080/13645706.2019.1626251.

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Woulfe, Peter, and Sean Gillespie. "Octavius 4D phantom implementation into patient specific quality assurance program." Physica Medica 30, no. 6 (2014): 719. http://dx.doi.org/10.1016/j.ejmp.2014.06.013.

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Prionas, Nicolas D., George W. Burkett, Sarah E. McKenney, Lin Chen, LinRobin L. ChenStern, and John M. Boone. "Development of a patient-specific two-compartment anthropomorphic breast phantom." Physics in Medicine and Biology 57, no. 13 (2012): 4293–307. http://dx.doi.org/10.1088/0031-9155/57/13/4293.

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Anderson, Jeff R., Walker L. Thompson, Abdulaziz K. Alkattan, et al. "Three-dimensional printing of anatomically accurate, patient specific intracranial aneurysm models." Journal of NeuroInterventional Surgery 8, no. 5 (2015): 517–20. http://dx.doi.org/10.1136/neurintsurg-2015-011686.

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ObjectiveTo develop and validate a method for creating realistic, patient specific replicas of cerebral aneurysms by means of fused deposition modeling.MethodsThe luminal boundaries of 10 cerebral aneurysms, together with adjacent proximal and distal sections of the parent artery, were segmented based on DSA images, and corresponding virtual three-dimensional (3D) surface reconstructions were created. From these, polylactic acid and MakerBot Flexible Filament replicas of each aneurysm were created by means of fused deposition modeling. The accuracy of the replicas was assessed by quantifying s

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Dukov, Nikolay, Kristina Bliznakova, Nikiforos Okkalidis, Tsvetelina Teneva, Elitsa Encheva, and Zhivko Bliznakov. "Thermoplastic 3D printing technology using a single filament for producing realistic patient-derived breast models." Physics in Medicine & Biology 67, no. 4 (2022): 045008. https://doi.org/10.1088/1361-6560/ac4c30.

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ABSTRACT <em>Objective</em>. This work describes an approach for producing physical anthropomorphic breast phantoms from clinical patient data using three-dimensional (3D) fused-deposition modelling (FDM) printing. <em>Approach</em>. The source of the anthropomorphic model was a clinical Magnetic Resonance Imaging (MRI) patient image set, which was segmented slice by slice into adipose and glandular tissues, skin and tumour formations; thus obtaining a four component computational breast model. The segmented tissues were mapped to specific Hounsfield Units (HU) values, which were derived from

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Bry, Victoria, Daniel Saenz, Evangelos Pappas, Niko Papanikolaou, and Karl Rasmussen. "82786 Quantification of the Accuracy of Stereotactic Radiosurgery using Surface Guided Imaging with 3D Printed Head Phantoms." Journal of Clinical and Translational Science 5, s1 (2021): 103. http://dx.doi.org/10.1017/cts.2021.665.

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ABSTRACT IMPACT: This work assesses clinical implementation of a surface guided imaging system to improve the accuracy radiation delivery for treatment of brain lesions using a patient CT derived head phantom. OBJECTIVES/GOALS: Advancements in radiotherapy design have made clinical demand for efficient and accurate methods to deliver stereotactic radiosurgery (SRS) for treatment of intracranial lesions. This study assesses the potential of using surface guided imaging for setup using a 3D patient specific head phantom. METHODS/STUDY POPULATION: A single isocenter, multiple metastases SRS plan

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Tan, Eddie T. W., Ji Min Ling, and Shree Kumar Dinesh. "The feasibility of producing patient-specific acrylic cranioplasty implants with a low-cost 3D printer." Journal of Neurosurgery 124, no. 5 (2016): 1531–37. http://dx.doi.org/10.3171/2015.5.jns15119.

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OBJECT Commercially available, preformed patient-specific cranioplasty implants are anatomically accurate but costly. Acrylic bone cement is a commonly used alternative. However, the manual shaping of the bone cement is difficult and may not lead to a satisfactory implant in some cases. The object of this study was to determine the feasibility of fabricating molds using a commercial low-cost 3D printer for the purpose of producing patient-specific acrylic cranioplasty implants. METHODS Using data from a high-resolution brain CT scan of a patient with a calvarial defect posthemicraniectomy, a s

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Silberstein, Jenna, Steven Tran, Yin How Wong, Chai Hong Yeong, and Zhonghua Sun. "Development of a 3D-Printed Chest Phantom with Simulation of Lung Nodules for Studying Ultra-Low-Dose Computed Tomography Protocols." Applied Sciences 15, no. 1 (2024): 309. https://doi.org/10.3390/app15010309.

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This study aimed to 3D print a patient-specific chest phantom simulating multiple lung nodules to optimise low-dose Computed Tomography (CT) protocols for lung cancer screening. The chest phantom, which was developed from a single patient’s chest CT images, was fabricated using a variety of materials, including polylactic acid (PLA), Glow-PLA, acrylonitrile butadiene styrene (ABS), and polyurethane resin. The phantom was scanned under different low-dose (LDCT) and ultra-low-dose CT (ULDCT) protocols by varying the kilovoltage peak (kVp) and milliampere-seconds (mAs). Subjective image quality o

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Frerker, Bernd, Elette Engels, Jason Paino, et al. "Fast and Fractionated: Correlation of Dose Attenuation and the Response of Human Cancer Cells in a New Anthropomorphic Brain Phantom." Biomimetics 10, no. 7 (2025): 440. https://doi.org/10.3390/biomimetics10070440.

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The results of radiotherapy in patients with primary malignant brain tumors are extremely dissatisfactory: the overall survival after a diagnosis of glioblastoma is typically less than three years. The development of spatially fractionated radiotherapy techniques could help to improve this bleak prognosis. In order to develop technical equipment and organ-specific therapy plans, dosimetry studies as well as radiobiology studies are conducted. Although perfect spheres are considered optimal phantoms by physicists, this does not reflect the wide variety of head sizes and shapes in our patient co

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Lai, Marco, Simon Skyrman, Flip Kor, et al. "Development of a CT-Compatible, Anthropomorphic Skull and Brain Phantom for Neurosurgical Planning, Training, and Simulation." Bioengineering 9, no. 10 (2022): 537. http://dx.doi.org/10.3390/bioengineering9100537.

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Background: Neurosurgical procedures are complex and require years of training and experience. Traditional training on human cadavers is expensive, requires facilities and planning, and raises ethical concerns. Therefore, the use of anthropomorphic phantoms could be an excellent substitute. The aim of the study was to design and develop a patient-specific 3D-skull and brain model with realistic CT-attenuation suitable for conventional and augmented reality (AR)-navigated neurosurgical simulations. Methods: The radiodensity of materials considered for the skull and brain phantoms were investiga

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Ginty, Olivia K., John M. Moore, Yuanwei Xu, et al. "Dynamic Patient-Specific Three-Dimensional Simulation of Mitral Repair." Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery 13, no. 1 (2018): 11–22. http://dx.doi.org/10.1097/imi.0000000000000463.

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Objective Planned mitral repair strategies are generally established from preoperative echocardiography; however, specific details of the repair are often determined intraoperatively. We propose that three-dimensional printed, patient-specific, dynamic mitral valve models may help surgeons plan and trial all the details of a specific patient's mitral repair preoperatively. Methods Using preoperative echocardiography, segmentation, modeling software, and three-dimensional printing, we created dynamic, high-fidelity, patient-specific mitral valve models including the subvalvular apparatus. We as

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Quadir, Kamila Afroj, Brian Zimmermann, Md Nahid Hossain, et al. "Quantification of Patient Specific Dosimetry in Radionuclide Therapy: A Phantom Study." Bangladesh Journal of Nuclear Medicine 17, no. 2 (2016): 134–37. http://dx.doi.org/10.3329/bjnm.v17i2.28199.

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The accuracy of patient specific dosimetry is correlated with measured organ activity by gamma camera and SPECT system. The assessment of the radiation-absorbed dose by patients undergoing nuclear medicine investigation requires accurate measurement of organ activity, biokinetics data, as well as physical data. Activities were estimated by using Ba-133 phantom with both planar and SPECT systems. The objective of the study was to measure the activities of Ba-133 from gamma camera images using both planar and SPECT studies and compare the reference values with the dose calibrator values to quant

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Laing, Justin, John Moore, Reid Vassallo, Daniel Bainbridge, Maria Drangova, and Terry Peters. "Patient-specific cardiac phantom for clinical training and preprocedure surgical planning." Journal of Medical Imaging 5, no. 02 (2018): 1. http://dx.doi.org/10.1117/1.jmi.5.2.021222.

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Ordóñez-Sanz, Caroline, Mark Cowen, Neda Shiravand, and Niall D. MacDougall. "CBCT imaging: a simple approach for optimising and evaluating concomitant imaging doses, based on patient-specific attenuation, during radiotherapy pelvis treatment." British Journal of Radiology 94, no. 1124 (2021): 20210068. http://dx.doi.org/10.1259/bjr.20210068.

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Objectives: A simple, robust method, for optimising cone-beam CT (CBCT) dose and image quality for pelvis treatment, based on patient-specific attenuation. Methods: Methods were investigated for grouping patients into four imaging categories (small [S], medium [M], large [L], extra large [XL]), based on planning-CT CTDIvol, and phantoms constructed to represent each group. CBCTs with varying kV, mA and ms honed in on the best settings, with a bladder noise of 25 HU. A patient pilot study clinically verified the new imaging settings. Results: The planning CTDIvol is a reliable method for groupi

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Bagdare, Priyusha, Swati Dubey, Sanjay Kumar Ghosh, and Shital Bhandigare. "Analysis of gamma index using in-house developed heterogeneous thorax phantom." International Journal of Radiology & Radiation Therapy 8, no. 1 (2021): 9–11. http://dx.doi.org/10.15406/ijrrt.2021.08.00289.

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Quality assurance (QA) before patient treatment plays a major role in complex radiotherapy (RT) treatment planning. Phantoms are the standard materials that are used for the pre-treatment QA of patients. Contemporary phantoms used in RT are mainly water-based, having simple geometry and of uniform density. These phantoms dose not replicate the exact heterogeneities of the actual human body. The present work aims to evaluate the results of relative dosimetry performed on in-house developed heterogeneous thorax phantom (HTP) using an electronic portal imaging device (EPID). To perform the relati

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Chueh, Ju-Yu, Kajo van der Marel, Matthew J. Gounis, et al. "Development of a high resolution MRI intracranial atherosclerosis imaging phantom." Journal of NeuroInterventional Surgery 10, no. 2 (2017): 143–49. http://dx.doi.org/10.1136/neurintsurg-2016-012974.

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Background and purposeCurrently, there is neither a standard protocol for vessel wall MR imaging of intracranial atherosclerotic disease (ICAD) nor a gold standard phantom to compare MR sequences. In this study, a plaque phantom is developed and characterized that provides a platform for establishing a uniform imaging approach for ICAD.Materials and methodsA patient specific injection mold was 3D printed to construct a geometrically accurate ICAD phantom. Polyvinyl alcohol hydrogel was infused into the core shell mold to form the stenotic artery. The ICAD phantom incorporated materials mimicki

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Warwick, J. M., S. Rubow, M. du Toit, E. Beetge, P. Carey, and P. Dupont. "The Role of CT-Based Attenuation Correction and Collimator Blurring Correction in Striatal Spect Quantification." International Journal of Molecular Imaging 2011 (April 6, 2011): 1–9. http://dx.doi.org/10.1155/2011/195037.

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Purpose. Striatal single photon emission computed tomography (SPECT) imaging of the dopaminergic system is becoming increasingly used for clinical and research studies. The question about the value of nonuniform attenuation correction has become more relevant with the increasing availability of hybrid SPECT-CT scanners. In this study, the value of nonuniform attenuation correction and correction for collimator blurring were determined using both phantom data and patient data. Methods. SPECT imaging was performed using 7 anthropomorphic phantom measurements, and 14 patient studies using [I-123]

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But-Husaim, U. U., L. A. Pirahova, A. S. Yarosh та ін. "ОСОБЕННОСТИ ПРИМЕНЕНИЯ ЗЕРКАЛЬНОЙ ВИЗУАЛЬНОЙ ОБРАТНОЙ СВЯЗИ У ПАЦИЕНТОВ С ФАНТОМНЫМИ БОЛЯМИ В КОНЕЧНОСТЯХ В УСЛОВИЯХ АТИПИЧНОГО ПОЛОЖЕНИЯ ФАНТОМА". Journal of the Grodno State Medical University 20, № 3 (2022): 291–96. http://dx.doi.org/10.25298/2221-8785-2022-20-3-291-296.

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One of the most interesting methods of neurorehabilitation is Mirror Visual Feedback (MVF). Despite the widespread information about effectiveness of MVF, specialists who have previously used this method but have not achieved positive results when working with patients, have many questions about the specific features of its application. Objective. The aim of our study was evaluation of the MVF effectiveness for reducing the severity of phantom pain in an amputated limb in the presence of atypical phantom location. Material and Methods: The study involved 29 patients with phantom limb pain. The

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Alva Sánchez, Mirko Salomón, Isabela Linhares, Carolina Maulaz, et al. "Implementación de un control de calidad de paciente específico en tratamientos de radioterapia con ArcCheck." Revista de la Facultad de Medicina Humana 24, no. 4 (2024): 43–51. http://dx.doi.org/10.25176/rfmh.v24i4.6793.

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Introduction: Quality control is essential to ensure safety and prevent errors in the administration of ionizing radiation across various radiotherapy techniques. Objective: To evaluate the performance of the ArcCheck detector with the goal of implementing a specific quality control technique for patients treated with dynamic arc therapy. Methods: Fifty patients treated with 6 MV and 10 MV energies on the Clinac® Varian CX were selected. Doses at the isocenter of each treatment plan were analyzed using a PMMA phantom (30 x 30 x 15 cm³) to validate reference values between the treatment plannin

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Yea, Ji Woon, Jae Won Park, Sung Kyu Kim, et al. "Feasibility of a 3D-printed anthropomorphic patient-specific head phantom for patient-specific quality assurance of intensity-modulated radiotherapy." PLOS ONE 12, no. 7 (2017): e0181560. http://dx.doi.org/10.1371/journal.pone.0181560.

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Zhu, Libing, Yi Du, Yahui Peng, Xincheng Xiang, and Xiangang Wang. "End-to-End QA with Polymer Gel Dosimeter for Photon Beam Radiation Therapy." Gels 9, no. 3 (2023): 212. http://dx.doi.org/10.3390/gels9030212.

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With the complexity and high demands on quality assurance (QA) of photon beam radiation therapy, end-to-end (E2E) QA is necessary to validate the entire treatment workflow from pre-treatment imaging to beam delivery. A polymer gel dosimeter is a promising tool for three-dimensional (3D) dose distribution measurement. The purpose of this study is to design a fast “one delivery” polymethyl methacrylate (PMMA) phantom with a polymer gel dosimeter for the E2E QA test of the photon beam. The one delivery phantom is composed of ten calibration cuvettes for the calibration curve measurement, two 10 c

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Jreije, Antonio, Lalu Keshelava, Mindaugas Ilickas, Jurgita Laurikaitiene, Benas Gabrielis Urbonavicius, and Diana Adliene. "Development of Patient Specific Conformal 3D-Printed Devices for Dose Verification in Radiotherapy." Applied Sciences 11, no. 18 (2021): 8657. http://dx.doi.org/10.3390/app11188657.

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In radiation therapy, a bolus is used to improve dose distribution in superficial tumors; however, commercial boluses lack conformity to patient surface leading to the formation of an air gap between the bolus and patient surface and suboptimal tumor control. The aim of this study was to explore 3D-printing technology for the development of patient-specific conformal 3D-printed devices, which can be used for the radiation treatment of superficial head and neck cancer (HNC). Two 3D boluses (0.5 and 1.0 cm thick) for surface dose build-up and patient-specific 3D phantom were printed based on rec

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Kok, H. Petra, Jort Groen, Akke Bakker, and Johannes Crezee. "Modelling Curved Contact Flexible Microstrip Applicators for Patient-Specific Superficial Hyperthermia Treatment Planning." Cancers 12, no. 3 (2020): 656. http://dx.doi.org/10.3390/cancers12030656.

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This paper describes a method to reconstruct bendable superficial hyperthermia applicators for routine clinical patient-specific treatment planning. The reconstruction uses a CT scan with a flexible silicone dummy applicator positioned on the patient. The curvature was approximated by two second-degree polynomial functions. A realistic treatment series was mimicked using a standard Alderson radiation therapy phantom and a treatment planning model was reconstructed from a CT scan. The variation among treatment curvatures was compared to the modelled curvature. The mathematical approximation of

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Heryani, Heryani, Ari D Reskianto, Choirul Anam, Ryan W Widhianto, and Arie C Martania. "Pembuatan In-House Phantom untuk Pengukuran Image Quality dan Dosimetri Sebagai Tool Optimasi Protokol Pemeriksaan CT Scan Thorak." Jurnal Pengawasan Tenaga Nuklir 3, no. 2 (2023): 52–58. http://dx.doi.org/10.53862/jupeten.v3i2.009.

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The computed tomography scanner (CT scan) protocol used in patient examinations must be continuously reviewed and optimized. Medical physicists evaluate the quality of the resulting image using an image quality phantom and evaluate radiation dose using a dosimetry phantom separately. Procuring a dosimetry phantom and image quality phantom for CT scans separately also requires a lot of money. Therefore, developing a dosimetry phantom and image quality phantom combined in one phantom is expected to be a solution to overcome the mentioned problem. This research aims to create a phantom as a combi

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Ger, R., EA Burgett, RR Price, DF Craft, SF Kry, and RM Howell. "WE-D-BRA-05: Pseudo In Vivo Patient Dosimetry Using a 3D-Printed Patient-Specific Phantom." Medical Physics 42, no. 6Part38 (2015): 3667–68. http://dx.doi.org/10.1118/1.4925932.

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Kalidindi, Yuktesh, Aravinda Krishna Ganapathy, Liam Cunningham, et al. "Customization of Computed Tomography Radio-Opacity in 3D-Printed Contrast-Injectable Tumor Phantoms." Micromachines 15, no. 8 (2024): 992. http://dx.doi.org/10.3390/mi15080992.

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Medical Imaging Phantoms (MIPs) calibrate imaging devices, train medical professionals, and can help procedural planning. Traditional MIPs are costly and limited in customization. Additive manufacturing allows for customizable, patient-specific phantoms. This study examines the CT attenuation characteristics of contrast-injectable, chambered 3D-printed phantoms to optimize tissue-mimicking capabilities. A MIP was constructed from a CT of a complex pelvic tumor near the iliac bifurcation. A 3D reconstruction of these structures composed of three chambers (aorta, inferior vena cava, tumor) with

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Malikov, Azad, Tural Rahimli, Rovshan Khalilzada, Sabir Etibarli, and özgür öcal. "Patient-Specific Highly Realistic Spine Surgery Phantom Trainers." Journal of Neurological Surgery Part A: Central European Neurosurgery, April 8, 2025. https://doi.org/10.1055/a-2576-7222.

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Introduction A realistic phantom created from a 3D-reconstructed digital patient model would enable researchers to investigate the morphological aspects of the pathologic spine, thereby resolving the issue of scarce cadaveric specimens. We designed a patient-specific, human-like, reliable, and cost-effective prototype of the examined pathologic spine through open-source editing software analysis, a desktop 3D printer, and alginate material. We aimed to validate that the major surgical steps and anatomy replicated the real surgery as it would be conducted in actual patients. Materials and metho

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Gallarello, Antonio, Andrea Palombi, Giacomo Annio, et al. "Patient-Specific Aortic Phantom With Tunable Compliance." Journal of Engineering and Science in Medical Diagnostics and Therapy 2, no. 4 (2019). http://dx.doi.org/10.1115/1.4044611.

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Abstract Validation of computational models using in vitro phantoms is a nontrivial task, especially in the replication of the mechanical properties of the vessel walls, which varies with age and pathophysiological state. In this paper, we present a novel aortic phantom reconstructed from patient-specific data with variable wall compliance that can be tuned without recreating the phantom. The three-dimensional (3D) geometry of an aortic arch was retrieved from a computed tomography angiography scan. A rubber-like silicone phantom was manufactured and connected to a compliance chamber in order

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Shapira, Nadav, Kevin Donovan, Kai Mei, et al. "Three-dimensional printing of patient-specific CT lung phantoms: A reader study." PNAS Nexus, February 1, 2023. http://dx.doi.org/10.1093/pnasnexus/pgad026.

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Abstract In modern clinical decision-support algorithms, heterogeneity in image characteristics due to variations in imaging systems and protocols hinders the development of reproducible quantitative measures including for feature extraction pipelines. With the help of a reader study, we investigate the ability to provide consistent ground-truth targets by using patient-specific 3D-printed lung phantoms. PixelPrint was developed for 3D-printing lifelike computed tomography (CT) lung phantoms by directly translating clinical images into printer instructions that control density on a voxel-by-vo

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Little, Callum D., Eleanor C. Mackle, Efthymios Maneas, et al. "A patient-specific multi-modality abdominal aortic aneurysm imaging phantom." International Journal of Computer Assisted Radiology and Surgery, April 10, 2022. http://dx.doi.org/10.1007/s11548-022-02612-4.

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Abstract Purpose Multimodality imaging of the vascular system is a rapidly growing area of innovation and research, which is increasing with awareness of the dangers of ionizing radiation. Phantom models that are applicable across multiple imaging modalities facilitate testing and comparisons in pre-clinical studies of new devices. Additionally, phantom models are of benefit to surgical trainees for gaining experience with new techniques. We propose a temperature-stable, high-fidelity method for creating complex abdominal aortic aneurysm phantoms that are compatible with both radiation-based,

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Hong, Dayeong, HaeKang Kim, Taehun Kim, Yong-Hee Kim, and Namkug Kim. "Development of patient specific, realistic, and reusable video assisted thoracoscopic surgery simulator using 3D printing and pediatric computed tomography images." Scientific Reports 11, no. 1 (2021). http://dx.doi.org/10.1038/s41598-021-85738-w.

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AbstractHerein, realistic and reusable phantoms for simulation of pediatric lung video-assisted thoracoscopic surgery (VATS) were proposed and evaluated. 3D-printed phantoms for VATS were designed based on chest computed tomography (CT) data of a pediatric patient with esophageal atresia and tracheoesophageal fistula. Models reflecting the patient-specific structure were fabricated based on the CT images. Appropriate reusable design, realistic mechanical properties with various material types, and 3D printers (fused deposition modeling (FDM) and PolyJet printers) were used to represent the rea

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Lacerda, Isabelle Viviane Batista de, José Wilson Vieira, Mércia Liane De Oliveira, and Fernando Roberto de Andrade Lima. "Patient-specific phantoms versus reference phantoms: a preliminary comparison on organs dose distribution." Brazilian Journal of Radiation Sciences 6, no. 2A (Suppl.) (2018). http://dx.doi.org/10.15392/bjrs.v6i2a.504.

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Discrepancies between ICRP phantoms and real patients lead to disparities on patient-dose estimations. This paper aims to compare distribution of dose in organs of male/female individualized-phantoms and ICRP reference phantoms. The absorbed dose estimation was performed using the EGSnrc Monte Carlo code and a parallel source algorithm. In this work were used an individualized-phantom for a man (1.73m/70.3kg) and another for a woman (1.63m/60.3kg) and the male and female ICRP reference phantoms. The comparison of the absorbed dose from each phantom gender was performed using the relative error

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Im, Jessica Y., Neghemi Micah, Amy E. Perkins, et al. "PixelPrint4D: A 3D Printing Method of Fabricating Patient-Specific Deformable CT Phantoms for Respiratory Motion Applications." Investigative Radiology, April 2, 2025. https://doi.org/10.1097/rli.0000000000001182.

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Objectives Respiratory motion poses a significant challenge for clinical workflows in diagnostic imaging and radiation therapy. Many technologies such as motion artifact reduction and tumor tracking have been developed to compensate for its effect. To assess these technologies, respiratory motion phantoms (RMPs) are required as preclinical testing environments, for instance, in computed tomography (CT). However, current CT RMPs are highly simplified and do not exhibit realistic tissue structures or deformation patterns. With the rise of more complex motion compensation technologies such as dee

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Papadakis, Antonios E., Vassiliki Giannakaki, John Stratakis, Marios Myronakis, Habib Zaidi, and John Damilakis. "Digital phantom versus patient‐specific radiation dosimetry in adult routine thorax CT examinations." Journal of Applied Clinical Medical Physics, May 22, 2024. http://dx.doi.org/10.1002/acm2.14389.

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AbstractPurposeThe aim of this study was to compare the organ doses assessed through a digital phantom‐based and a patient specific‐based dosimetric tool in adult routine thorax computed tomography (CT) examinations with reference to physical dose measurements performed in anthropomorphic phantoms.MethodsTwo Monte Carlo based dose calculation tools were used to assess organ doses in routine adult thorax CT examinations. These were a digital phantom‐based dosimetry tool (NCICT, National Cancer Institute, USA) and a patient‐specific individualized dosimetry tool (ImpactMC, CT Imaging GmbH, Germa

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Choi, Yeonho, Ik Jae Lee, Kwangwoo Park, et al. "Patient-Specific Quality Assurance Using a 3D-Printed Chest Phantom for Intraoperative Radiotherapy in Breast Cancer." Frontiers in Oncology 11 (March 15, 2021). http://dx.doi.org/10.3389/fonc.2021.629927.

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This study aims to confirm the usefulness of patient-specific quality assurance (PSQA) using three-dimensional (3D)-printed phantoms in ensuring the stability of IORT and the precision of the treatment administered. In this study, five patient-specific chest phantoms were fabricated using a 3D printer such that they were dosimetrically equivalent to the chests of actual patients in terms of organ density and shape around the given target, where a spherical applicator was inserted for breast IORT treatment via the INTRABEAM™ system. Models of lungs and soft tissue were fabricated by applying in

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