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Rozprawy doktorskie na temat „Periodontal Ligament Cells”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Gay, Isabel C. "Isolation and characterization of human periodontal ligament stem cells." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2007. http://www.mhsl.uab.edu/dt/2007m/gay.pdf.

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Winning, Lewis. "The osteogenic potential of periodontal ligament stem cells." Thesis, Queen's University Belfast, 2018. https://pure.qub.ac.uk/portal/en/theses/the-osteogenic-potential-of-periodontal-ligament-stem-cells(e5fdef0e-d55b-42b6-acb5-75a617b43edd).html.

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Oliveira, Guilherme Henrique Costa 1988. "Avaliação do papel do marcador de superfície CD166 na diferenciação osteoblástica/cementoblástica de células mesenquimais indiferenciadas do ligamento periodontal de humanos." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/290297.

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Orientador: Karina Gonzales Silvério Ruiz<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-27T02:48:19Z (GMT). No. of bitstreams: 1 Oliveira_GuilhermeHenriqueCosta_M.pdf: 1623320 bytes, checksum: af95c8df2b95e735fcae950c2260eb9e (MD5) Previous issue date: 2015<br>Resumo: Células mesenquimais isoladas do ligamento periodontal (PDLSCs) de dentes humanos mostraram ser multipotentes e possuem a capacidade de se diferenciar em adipócitos osteoblastos in vitro. Além disso, possuem a capacidade de formar tec

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Wescott, David Clark, and n/a. "Osteogenic gene expression by human periodontal ligament cells under cyclic mechanical tension." University of Otago. School of Dentistry, 2008. http://adt.otago.ac.nz./public/adt-NZDU20081202.131453.

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Background and objectives: The most widely accepted tooth movement model is defined by the pressure-tension hypothesis. An orthodontic force applied to a tooth generates areas of compression and tension in the periodontal ligament (PDL), which are transmitted to the alveolar bone. Areas of tissue exposed to tensile strain undergo bone deposition, whereas areas of tissue exposed to compressive strain undergo bone resorption. We propose that human PDL cells in monolayer culture exposed to tensile mechanical strain would express multiple genes involved in osteogenesis. Materials and Methods: Hu

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Nuersailike, Abuduwali [Verfasser]. "Characterization of Parathyroid Hormone 1 Receptor in Periodontal Ligament Cells / Abuduwali Nuersailike." Bonn : Universitäts- und Landesbibliothek Bonn, 2012. http://d-nb.info/1044080973/34.

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Farag, Amro Ahmed Mahmoud. "Decellularized Tissue Engineered Constructs Using Cell Sheet Technology." Thesis, Griffith University, 2016. http://hdl.handle.net/10072/367720.

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The periodontium is a complex structure that is comprised of soft tissue components the gingiva and periodontal ligament, as well as hard tissue components in the form of alveolar bone and cementum. Human periodontal ligament cells (HPDLCs) and their extracellular matrix are regarded as essential components to achieve successful periodontal regeneration when treating periodontal lesions. In the present study, cell sheet technology was utilized to fabricate periodontal ligament cell sheets. These cell sheets were subsequently decellularized to isolate and preserve the extracellular component st

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7

Salmon, Richard J. "Prevalence of mast cells within the periodontal ligament of the developing rat molar /." Title page, contents and summary only, 2000. http://web4.library.adelaide.edu.au/theses/09DC/09dcs172.pdf.

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Thesis (D.Clin.Dent.)--University of Adelaide, Dental School, 2001.<br>Second copy has title: Prevalence and determination of mast cell type within the periodontal ligament of the developing rat tooth. Bibliography: leaves 109-119.

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Adams, A. M. "In vitro biocompatibility studies of dental restorative materials using human periodontal ligament cells." Thesis, University of Newcastle Upon Tyne, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287331.

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Pelaez, Daniel. "Role of Mechanical Strain on the Cardiomyogenic Differentiation of Periodontal Ligament Derived Stem Cells." Scholarly Repository, 2011. http://scholarlyrepository.miami.edu/oa_dissertations/573.

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The application of cellular therapies for the treatment of myocardial infarction has provided encouraging evidence for the possibility of cellular therapies to restore normal heart function. However, questions still remain as to the optimal cell source, pre-conditioning methods and delivery techniques for such an application. Here I propose the use of a unique population of stem cells arising from the embryonic neural crest. These cells were shown to express neural crest markers as well as pluripotency-associated markers. Furthermore, the cells were shown to express proteins essential to the

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Lin, Deborah G. "Storage conditions of avulsed teeth affect the phenotype of cultured human periodontal ligament cells." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0003/MQ45972.pdf.

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Lagerholm, Sara. "Isolation and Characterization of Mesenchymal Stem Cells from the Periodontal Ligament of Healthy Teeth." Thesis, Malmö universitet, Odontologiska fakulteten (OD), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-19683.

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ABSTRAKT:Isolering och karaktärisering av mesenkymala stamceller från periodontalligamentet hos friskatänderSYFTE: Att isolera och odla celler från periodontalligamentet samt karaktärisera dem sommesenkymala stamceller.MATERIAL OCH METOD: Friska premolarer gjordes tillgängliga vid ortodontiskaextraktioner. Den mellersta 1/3 av periodontalligamentet skrapades varpå en enzymatiskmetod användes för isolering av individuella celler. Resulterande celler odlades understandardiserade metoder. Karaktärisering av celler skedde genom flödescymetri med 2 olikapaneler av cellyta markörer; en för etablerat

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Aidoukovitch, Alexandra. "Effects of strontium on osteogenic capacity and proliferation of human periodontal ligament cells and osteoblasts." Thesis, Malmö högskola, Odontologiska fakulteten (OD), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-19681.

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Strontium (Sr2+) är det aktiva ämnet i läkemedel som används för att reducera frakturrisken hos patienter som lider av osteoporos. På senare tid har Sr2+ kombinerats med olika biomaterial i syfte att gynna benbildning, emellertid är ämnet vagt studerat avseende effekten på parodontala vävnader. Trots omfattande användning, är verkningsmekanismer av Sr2+ inte helt klarlagda. Denna studie syftar därmed till att utvärdera effekten av Sr2+ på humana parodontalligament-celler (PDL-celler) och osteoblaster avseende proliferation och osteogen aktivitet. Odlade humana PDL celler och osteoblastcellinje

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13

El-Hossary, Wafaa Hassanein Hassan. "The effect of cyclic tensile strain on gene expression of cultured human periodontal ligament cells." Thesis, University of Leeds, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509041.

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Objectives: To analyse the changes in gene expression in a population of human periodontal ligament (HPDL) cells exposed to cyclic tensile strain in a three dimensional culture system. Results: Cells derived from extracted teeth were shown to represent a mixed population with greater than 95% of cells expressing markers characteristic of periodontal ligament fibroblasts with an oestobastic phenotype with a smaller sub-population (2-3%) of stem cells. Cells from several different donors were subjected to an applied tensile strain (5%) and compared to unstressed controls. RNA extracted immediate

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14

Saoji, Nachiket A. "Effect of bisphosphonate on osteogenic differentiation of pulp and PDL cells." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2009r/saoji.pdf.

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15

Martinez, Catalina. "The Effects of Dynamic Culturing Environments on Cell Populations Relevant to Heart Valve Tissue Engineering." FIU Digital Commons, 2011. http://digitalcommons.fiu.edu/etd/505.

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The design of a tissue engineered pulmonary valve (TEPV) involves cells source(s), scaffold, in vitro conditioning system and the functional stability of the TEPV in vivo. Vascular cells (pulmonary artery smooth muscle (SMCs) and endothelial cells (ECs)) and periodontal ligament derived stem cells (PDLSCs) are relevant sources for the designing of TEPVs. In this study, labeling of these cell populations with super paramagnetic iron oxide microparticles along with concomitant usage of transfection agents was followed by visualization using magnetic resonance, while Intracellular iron oxide was

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16

Soares, Diego Moura. "Influ?ncia da laserterapia na prolifera??o de c?lulas-tronco do ligamento periodontal humano." Universidade Federal do Rio Grande do Norte, 2013. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17838.

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Made available in DSpace on 2014-12-17T15:43:54Z (GMT). No. of bitstreams: 1 DiegoMS_DISSERT.pdf: 1792102 bytes, checksum: 305ff686e7a1606e27026b528fd1d091 (MD5) Previous issue date: 2013-01-25<br>Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior<br>Low level laser irradiation (LLLI) has been used in Dentistry to promote wound healing and tissue regeneration. The literature shows a positive effect of LLLI on cell proliferation, but little is known about their effectiveness in promoting stem cells proliferation. The aim of this study was to evaluate the effect of LLLI on the p

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17

Pinkerton, Mark Neil, and n/a. "The molecular basis of orthodontic tooth movement : cytokine signaling by PDL cells in tension an in vitro study." University of Otago. School of Dentistry, 2007. http://adt.otago.ac.nz./public/adt-NZDU20071207.161056.

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The pressure-tension hypothesis is the governing dogma of orthodontic tooth movement. This theory proposes that the application of loads to the crown of a tooth during orthodontic mechano-therapy results in differential site-specific reactionary strains in the para-dental tissues. Briefly, following the application of orthodontic load the bone and periodontal ligament (PDL) on one side of the tooth is placed in compression favoring bone resorption, while on the other side of the tooth they are placed in tension favoring osteogenesis The present in vitro model provides a surrogate for the PDL o

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18

Shaheen, Ibrahim Ahmed. "Studies of the effects of recombinant human bone morphogenetic protein-2 on human periodontal ligament cells in vitro." Thesis, Queen Mary, University of London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267481.

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VECCHIATINI, Renata. "Mesenchymal stem cells from Wharton's Jelly and periodontal ligament: reliable not controversial sources for osteogenic differentiation and regenerative medicine." Doctoral thesis, Università degli studi di Ferrara, 2011. http://hdl.handle.net/11392/2388818.

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Mesenchymal stem cells (MSCs) are uniquely capable of crossing germinative layers borders (these cell populations are able to differentiate towards ectoderm-, mesoderm- and endoderm- derived lineages) and are viewed as promising cells for regenerative medicine approaches in several diseases. Some undoubtedly limiting factors for the clinical use of MSCs, i.e. for the repair of bone defects, are related to many different problems, that only partially today can be overcome through ex-vivo expansion and cells modification strategies. Considering MSCs sources, the use of fetal annexes-deriv

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Alves, Luciana Bastos. "Ades?o de c?lulas mesenquimais da medula ?ssea de camundongos e do ligamento periodontal de ratos a diferentes superf?cies de tit?nio: estudo comparativo in vitro." Universidade Federal do Rio Grande do Norte, 2008. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17048.

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Made available in DSpace on 2014-12-17T15:30:52Z (GMT). No. of bitstreams: 1 LucianaBA.pdf: 299762 bytes, checksum: b2ed4a69274795e7585d8ffaeab0f96d (MD5) Previous issue date: 2008-12-19<br>The present experiment used cell culture to analyze the adhesion capacity of mouse mesenchymal bone marrow cells and rat periodontal ligament to different titanium surfaces. Grade II ASTM F86 titanium discs 15mm in diameter and 1.5mm thick were used and received 2 distinct surface treatments (polished and cathodic cage plasma nitriding). The cells were isolated from the mouse bone marrow and rat periodont

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21

Vernon, Lauren Louise. "A Comparison of the Osteogenic Tissue Engineering Potential of Dental-Derived Stem Cell Lines: Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs) vs. Periodontal Ligament Stem Cells (PERIOS)." Scholarly Repository, 2010. http://scholarlyrepository.miami.edu/oa_theses/19.

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The goal of this study is to assess the osteogenic potential of two types of dental stem cell lines within a tissue engineering application. More specifically, the goal of this study is to find a readily abundant cell source with capacity to express an osteogenic phenotype. There are two parameters utilized to evaluate tissue engineering potential of cells: proliferation rate and differentiation potential. Briefly, proliferation rate is the speed at which cells divide and differentiation potential determines if cells are capable of committing towards specific lineages (e.g. osteogenic). The

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Alves, Luciana Bastos. "Expressão dos fenótipos fibroblástico e osteoblástico em culturas tridimensionais na presença de partículas de vidro bioativo." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/58/58132/tde-22102012-090829/.

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O objetivo deste estudo foi analisar a expressão dos fenótipos fibroblástico e osteoblástico em culturas tridimensionais na presença ou não de partículas de vidro bioativo. Fibroblastos derivados do ligamento periodontal humano (hPDLF) e células osteogênicas da calvária de rato recém-nascidos foram plaqueadas em superfícies bidimensionais - lamínulas de plástico ThermanoxTM (controle); superfícies colágenas bidimensionais - ThermanoxTM revestidas por colágeno I sem partículas de vidro bioativo (2D) e com partículas de vidro bioativo (2D+VB); e em gel colágeno tridimensional sem vidro bioativo

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Vasconcelos, Rodrigo Gadelha. "A influ?ncia da criopreserva??o nas c?lulas mesenquimais indiferenciadas do ligamento periodontal de humanos an?lise comparativa in vitro." Universidade Federal do Rio Grande do Norte, 2011. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17064.

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Made available in DSpace on 2014-12-17T15:30:56Z (GMT). No. of bitstreams: 1 RodrigoGV_DISSERT.pdf: 1378162 bytes, checksum: aa53c22bf2541e2d42d5b5659f380375 (MD5) Previous issue date: 2011-02-04<br>Cryopreservation is a process where cells or biological tissues are preserved by freezing at very low temperatures and aims to cease reversibly, in a controlled manner, all the biological functions of living tissues, i.e., maintain cell preservation so that it can recover with high degree of viability and functional integrity. This study aimed to evaluate the influence of cryopreservation on the

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Fritz, Jason Ronald. "The Chondrogenesis of PDLs by Dynamic Unconfined Compression Is Dependent on p42/44 and Not p38 or JNK." Scholarly Repository, 2009. http://scholarlyrepository.miami.edu/oa_theses/225.

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Articular cartilage lines the surfaces of load bearing joints and has limited capabilities for self-repair due to its alymphatic and avascular structure. Attempts at making repairs to this tissue has resulted in substandard materials and/or causing further injury to the patient making this tissue a prime candidate for tissue engineering studies incorporating adult stem cells. These studies have given rise to some answers and many more questions including a search for alternative stem cell sources and what biochemical changes the cells undergo during the differentiation of these stem cells into

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Marciniak, Jana [Verfasser]. "Investigation of Heat Shock Protein 70 and Toll-like Receptor 4 functions during inflammation reaction by mechanical compression in human periodontal ligament cells / Jana Marciniak." Bonn : Universitäts- und Landesbibliothek Bonn, 2021. http://d-nb.info/1239729901/34.

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Jin, Jieqi [Verfasser], and Matthias [Akademischer Betreuer] Folwaczny. "The effects of low molecular weight hyaluronan on the cementogenic, ligamentogenic and osteogenic differentiation of human mesenchymal stem cells (hMSCs) and periodontal ligament cells (PDL-hTERTs) / Jieqi Jin ; Betreuer: Matthias Folwaczny." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2018. http://d-nb.info/1197536841/34.

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Mattar, Marco Antonio [UNIFESP]. "Modelo de compressão contínua na cultura de fibroblastos derivados do ligamento periodontal humano." Universidade Federal de São Paulo (UNIFESP), 2015. http://repositorio.unifesp.br/handle/11600/39316.

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Submitted by Maria Anália Conceição (marianaliaconceicao@gmail.com) on 2016-06-27T14:03:01Z No. of bitstreams: 1 Publico-NOVO-16.pdf: 1167031 bytes, checksum: f37b93c03ff1aafc658b116d6ba3bc6b (MD5)<br>Approved for entry into archive by Maria Anália Conceição (marianaliaconceicao@gmail.com) on 2016-06-27T14:21:07Z (GMT) No. of bitstreams: 1 Publico-NOVO-16.pdf: 1167031 bytes, checksum: f37b93c03ff1aafc658b116d6ba3bc6b (MD5)<br>Made available in DSpace on 2016-06-27T14:21:07Z (GMT). No. of bitstreams: 1 Publico-NOVO-16.pdf: 1167031 bytes, checksum: f37b93c03ff1aafc658b116d6ba3bc6b (MD5) P

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Saito, Miki Taketomi 1986. "Caracterização do fenótipo de células mesenquimais indiferenciadas do ligamento periodontal de humanos com potencial para diferenciação osteoblásticas/cementoblástica." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/289493.

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Orientador: Karina Gonzáles Silvério Ruiz<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-22T14:42:06Z (GMT). No. of bitstreams: 1 Saito_MikiTaketomi_M.pdf: 1292081 bytes, checksum: 368c2e71f9e5362b6da282ee020ff058 (MD5) Previous issue date: 2013<br>Resumo: Vários estudos têm sido conduzidos com o intuito de isolar e caracterizar células com fenótipo mesenquimal indiferenciado a partir do ligamento periodontal de humanos e avaliar o seu potencial em promover a neoformação dos tecidos periodontais. A

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Dreyer, Craig William. "Clast cell activity in a model of aseptic root resorption." Title page, table of contents and abstract only, 2002. http://web4.library.adelaide.edu.au/theses/09PH/09phd778.pdf.

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Albiero, Mayra Laino 1988. "Efeito do lipopolissacarídeo bacteriano sobre as propriedades biológicas das células mesenquimais indiferenciadas do ligamento periodontal de humanos." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/289492.

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Orientador: Karina Gonzales Silvério Ruiz<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-22T13:33:07Z (GMT). No. of bitstreams: 1 Albiero_MayraLaino_M.pdf: 1767389 bytes, checksum: 14c8bc6c823503f78c08850abc5ed95b (MD5) Previous issue date: 2013<br>Resumo: O objetivo do presente estudo foi avaliar se a exposição das células mesenquimais indiferenciadas do ligamento periodontal (PDLMSCs) ao lipopolissacarídeo da Porphyromonas gingivalis (Pg) e da Escherichia coli (Ec), levaria a alterações biológicas

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31

Carrió, Bertrán Neus. "Comparación del perfil proteico del ligamento periodontal versus el hueso alveolar con el complejo periodontal diferenciado a partir de las DPPSCs." Doctoral thesis, Universitat Internacional de Catalunya, 2017. http://hdl.handle.net/10803/461770.

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El tratamiento de los defectos infraóseos es uno de los objetivos de la terapia de la enfermedad periodontal. La literatura actual reporta ciertas limitaciones en cuanto a la predictibilidad de las técnicas, por consiguiente, siguen siendo necesarios modelos predictivos y estrategias regenerativas más precisas. Uno de los problemas actuales desde un punto de vista clínico, es el desconocimiento estructural de los tejidos que deseamos regenerar. Definir las proteínas expresadas en el periodonto podría ayudar a establecer estrategias clínicas regenerativas más fiables. El presente estudio

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Silva, Ivanilton Alan de Souza. "Análise da influência de diferentes meios de armazenagem na viabilidade de fibroblastos e na composição iônica da dentina radicular: estudo in vitro." Universidade Federal de Sergipe, 2015. https://ri.ufs.br/handle/riufs/5898.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>For preservation of periodontal ligament cells after one tooth avulsion becomes necessary to determine a storage medium. The aim of this study was to analyze the preservation of human fibroblast cells and analyze the composition of root dentin of bovine teeth in different storage media. Immortalized human fibroblasts cells were grown in flasks containing Dulbecco's modified eagle medium (DMEM), and ffter reaching confluence the cells were trypsinized, counted by hemocytometer and plated. The culture medium was removed from

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Scheiner, Mark A. "A T.E.M. investigation of endothelial cell junctions in marmoset incisor periodontal ligament following orthodontic extrusion and retention /." Title page, table of contents and summary only, 1996. http://web4.library.adelaide.edu.au/theses/09DM/09dms359.pdf.

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Bittencourt, Tatiane Sampaio. "Análise in vitro da N-Acetilcisteína em fibroblastos do ligamento periodontal estimulados por LPS bacteriano." Universidade Estadual Paulista (UNESP), 2018. http://hdl.handle.net/11449/153542.

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Submitted by TATIANE SAMPAIO BITTENCOURT (dratatisampaio@gmail.com) on 2018-04-11T16:45:24Z No. of bitstreams: 1 Dissertação final - Tatiane Sampaio Bittencourt - UNESP.pdf: 2306748 bytes, checksum: 2c8b1dc80443dde5641b966081d8e34f (MD5)<br>Approved for entry into archive by Silvana Alvarez null (silvana@ict.unesp.br) on 2018-04-16T15:54:30Z (GMT) No. of bitstreams: 1 bittencourt_ts_me_sjc.pdf: 2306748 bytes, checksum: 2c8b1dc80443dde5641b966081d8e34f (MD5)<br>Made available in DSpace on 2018-04-16T15:54:30Z (GMT). No. of bitstreams: 1 bittencourt_ts_me_sjc.pdf: 2306748 bytes, checksum: 2c

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Kelsey, William Patrick V. "Proteomic Analysis of the Nuclear Membranes of Human Periodontal Ligament Fibroblast and Gingival Fibroblast Cell Types: A Comparison Study." Columbus, Ohio : Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1243618431.

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Owyoung, Jeremy B. "Bioactive coating glass and commercial bioglass enhance gene expression, protein expression, and matrix formation of human Periodontal Ligament Fibroblasts during osteogenesis." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1465487.

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Ribeiro, Rodrigo Alves. "Avalia??o in vitro da ades?o e prolifera??o de c?lulas mesenquimais do ligamento periodontal humano em diferentes superf?cies de tit?nio." Universidade Federal do Rio Grande do Norte, 2011. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17065.

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Made available in DSpace on 2014-12-17T15:30:56Z (GMT). No. of bitstreams: 1 RodrigoAR_DISSERT.pdf: 1824764 bytes, checksum: fbfdfd8c2f743e113f6663106fda888b (MD5) Previous issue date: 2011-02-04<br>In the last years, many scientific researches in implantology have been focused on alternatives that would provide higher speed and quality in the process of osseointegration. Different treatment methods can be used to modify the topographic and chemical properties of titanium surface in order to optimize the tissue-implant reactions by a positive tissue response. This study aimed to evaluate the

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Rodrigues, Thaisângela. "Análise da regulação de genes associados ao metabolismo do fosfato em células da polpa e ligamento periodontal e suas associações na regeneração periodontal = estudo "in vitro" e "in vivo"." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/289034.

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Orientadores: Francisco Humberto Nociti Junior, Karina Gonzales Silvério Ruiz<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-17T15:11:27Z (GMT). No. of bitstreams: 1 Rodrigues_Thaisangela_D.pdf: 14210209 bytes, checksum: 51042175513bdc9b288a951af21a21ac (MD5) Previous issue date: 2011<br>Resumo: A formação deficiente do cemento acelular sobre a raiz dentinária de pacientes com hipofosfatasia (HPP) elucida a importância da expressão local da enzima fosfatase alcalina (TNAP) durante a cementogênese. Os obj

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Correia, Vera de Fátima Padrão. "Avaliação in vitro da citotoxicidade do alendronato de sódio sobre fibroblastos de ligamento periodontal de humanos em cultura celular." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/23/23145/tde-06062005-141644/.

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Os processos de reabsorção radicular externa, geralmente, estão associados aos traumatismos dentários que atingem os tecidos de sustentação e suporte, principalmente a avulsão e a intrusão. A terapia endodôntica nesses casos, deve visar a estabilização ou paralisação deste processo através da utilização de medicação intracanal que possa inibir a atividade osteoclástica, como os bisfosfonatos desde que, esse fármaco seja biocompatível. Neste sentido, o objetivo desse estudo foi analisar a citotoxicidade do alendronato de sódio sobre fibroblastos do ligamento periodontal humano em cultura celula

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Gabriele, Lilian Gobbo de Freitas Bueno. "Avaliação dos eixos ECA / ANG II / AT1 e ECA-2 / ANG (1-7) / MAS em fibroblastos de gengiva e ligamento periodontal humanos estimulados por IL-1&#x3B2 e sua contribuição na produção e regulação de citocinas e quimiocinas." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/25/25149/tde-07112016-104708/.

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O Sistema renina-angiotensina (SRA) tem sido relatado como um importante modulador de processos inflamatórios e imunológicos, incluindo a doença periodontal (DP). Estudos sugerem neste sistema um eixo alternativo (ECA-2 /ANG(1-7) /MAS) que atuaria como um contra-regulador de efeitos mediados pelo clássico eixo (ECA /ANGII /AT1). Sabe-se que bactérias periodontopatogênicas, como a Porphyromonas gingivalis (Pg), possuem componentes bioativos de membrana (ex. lipopolissacarídeos-LPS) capazes de induzir uma forte resposta imune no hospedeiro devido à liberação de citocinas nas células, entre elas

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Chang, Yi-Tao, and 張益滔. "Investigation of cell regeneration in human periodontal ligament cells." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/eax4v4.

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碩士<br>中國醫藥大學<br>牙醫學系碩士班<br>102<br>[Objective] The activity of cell regeneration in human periodontal ligament cells (PDLCs) was characterized. [Materials and methods] The human PDLCs were isolated from middle third of the tooth root and cultured by using outgrowth or enzyme-digested methods. The cell viability of the PDLCs after cryopreservation with dimethyl sulfoxide (DMSO) was evaluated. The success rate of re-implanted PDLCs onto the root after treatment with ethylenediaminetetraacetic acid (EDTA) was also determined. [Results and Discussion] Our data indicated that outgrowth culture repre

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"Retinal differentiation potential of postnatal human periodontal ligament-derived undifferentiated cells." 2013. http://library.cuhk.edu.hk/record=b5884481.

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Huang, Li.<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2013.<br>Includes bibliographical references (leaves 162-194).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Abstract also in Chinese.

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Ming-WeiJan and 冉明偉. "Comparing stem cell associated genes expression between dental pulp and periodontal ligament cells." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/94554656940412205133.

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碩士<br>國立成功大學<br>口腔醫學研究所<br>102<br>In previous studies, we can see that few studies have discussed that difference exist between stem cell markers. In this study, we have three objective. First, we compare dental pulp and periodontal ligament and look at the difference between human stem cell associated genes. Next, we look for markers that are significantly different between these two types of cells. And look at the function of those stem cell associated genes. Last, we explore the clinical expression between dental pulp and periodontal ligament. Our analysis indicated that different tissues h

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Mi, Hsin-Wu, and 秘心吾. "In vitro transformation of periodontal ligament fibroblasts( PF cells) and characterization." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/14993343658933684657.

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碩士<br>國立臺灣大學<br>口腔生物科學研究所<br>92<br>The core of periodontal therapy is to ensure the regeneration of the tissue that has been destroyed by periodontitis. So the periodontal regeneration requires restitution of the periodontal attachment apparatus, i.e., new bone formation, new cementum deposition upon the denuded root surface, and insertion of functionally-oriented new collegen fibers targeting the periodontal ligament（PL）into the new bone and new cementum. The origins of progenitor cells responsible for the formation of these tissues have long been suggested to be mainly derived from PL tissue

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Hsu, Yu-Jen, and 許佑任. "Mechanical Tensional Force Regulates Expression of Periostin in Human Periodontal Ligament Cells." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/66779506327922772311.

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碩士<br>國立臺灣大學<br>臨床牙醫學研究所<br>103<br>Periostin was classified as one of the matricellular proteins predominantly expressed in collagen-rich connective tissues, including heart valves, tendons, perichondrium, periosteum, and periodontal ligament. The periostin knock-out mice showed loss of the tissue integrity of the periodontium in response to mechanical loading, and developed an early-onset periodontal disease-like phenotype. Previous studies suggest that periostin is essential for connective tissue homeostasis and important to maintain the integrity and function of periodontal ligament in resp

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Chen, Fang-Chin, and 陳芳津. "The Involvement of miR-146a in the Differentiation of Periodontal Ligament Cells." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/28902089323538272843.

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碩士<br>國立陽明大學<br>臨床牙醫學研究所<br>96<br>Periodontal ligament (PDL) cells exhibit potentials in hard and soft tissue regeneration because of their mutipotential properties. Osteoblastic line of differentiation of PDL cells will occur under special condition. In bone metabolism, pre-osteoclasts differentiate into osteoclasts via activation of NF-κB signaling pathway. MicroRNAs, small RNAs, regulating the gene expression at the post-transcription level, are associated with the cell process, including cell differentiation. miR-146a, one of microRNAs, was reported involved in the regulation of NF-κB. The

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Chung, Hsiang-Yi, та 鍾享艗. "The influence of TGF-β on osteogenic differentiation in periodontal ligament cells". Thesis, 2012. http://ndltd.ncl.edu.tw/handle/24617829791515760500.

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碩士<br>國立臺灣大學<br>臨床牙醫學研究所<br>100<br>Periodontal disease would led to destruction of periodontal tissue, reduce periodontal supporting structure, and finally led to tooth loss. The development of periodontal therapy starts from infection control to tissue regeneration in order to regenerate the healthy tissue surrounding tooth structure. Discovery from tissue engineering found many growth factors leading to tissue regeneration. Recently, transforming growthβ(TGF-β)and connective tissue growth factor (CTGF) can induce bone formation and osteoblast differentiation. However, previous studies show l

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Di, Costanzo Giuseppe. "Utilização das células derivadas do ligamento periodontal na recuperação dos tecidos periodontais." Master's thesis, 2018. http://hdl.handle.net/10284/7476.

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A periodontite é uma doenças inflamatória causada por defice de higiene oral e/ou asociada á doenças sistemicas, que leva a uma perda progressiva do osso alveolar e ao aumento da profundidade de sondagem, e existem pesquisas na aréa da periodontologia para procurar uma solução aos efeitos desta doença. O objectivo deste trabalho é de demonstrar que o avanço da pesquisa sobre as células estaminais pode estar interligado á uma solução para a periodontite, através do estudo sobre as PDLSCs, e da implantação destas células, para uma parcial recuperação do tecidos periodontais. Em estudos conduzido

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Mao, Chien-Nong, and 毛健農. "Effects of Glucosamine on Proliferation and Osteogenic Differentiation of Human Periodontal Ligament Cells." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/81756878016369616126.

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碩士<br>國立臺灣大學<br>臨床牙醫學研究所<br>100<br>Glucosamine is monomer of chitosan, and an kind of amnio-monosaccharide. It is also be called 2-amino-2deoxy-glucose，and is the NH2 group substituted the H2O group of glucose。Some studies reported glucosamine can up-regulate the gene expression in chondrocyte, minimize degradation of cartilage matrix, and supply the source for synthesis of aggrecan. Other studies reported glucosamine can down-regulation some inflammatory cytokines, like COX-2、IL-1β、TNF-α, and also can promote differentiation of osteoblast. In order to investigate if glucosamine can be applied

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Chen, Ling-Ling, and 陳玲玲. "The effect of long-term hypoxic culture on human periodontal ligament stem cells." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/73690516965954189666.

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碩士<br>國立陽明大學<br>口腔生物研究所<br>102<br>Periodontitis is a common oral disease and a leading cause of tooth loss in adults. The ultimate goal of periodontal therapy is the regeneration of the tissues destroyed as a result of periodontal disease. Achieving predictable periodontal regeneration remains a challenge nowadays. Periodontal ligament stem cells (PDLSCs) are involved in the periodontal wound healing. PDLSC-based therapeutics demonstrates promising results in periodontal regeneration in various animal models. Since PDLSCs isolated from periodontal ligament tissue are quite limited, long-term c

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