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1

Rambow-Larsen, Amy Alison. "Assembly and secretion of pertussis toxin by bordetella pertussis." Cincinnati, Ohio : University of Cincinnati, 2003. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=ucin1066417734.

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RAMBOW-LARSEN, AMY ALISON. "ASSEMBLY AND SECRETION OF PERTUSSIS TOXIN BY BORDETELLA PERTUSSIS." University of Cincinnati / OhioLINK, 2003. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1066417734.

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3

Hegerle, Nicolas. "Evolution of Bordetella pertussis and Bordetella parapertussis under acellular Pertussis vaccine pressure : What future for whooping cough and Pertussis vaccination ?" Paris 7, 2014. http://www.theses.fr/2014PA077038.

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La coqueluche est une maladie respiratoire dangereuse pour les nouveaux nés non vaccinés. Celle-ci est causée par Bordetella pertussis et Bordetella parapertussis, deux bactéries à gram négatif dont le seul hôte connu est l'homme. L'introduction de la vaccination contre B. Pertussis, le pathogène majoritairement responsable de cette maladie, à grandement impacté l'épidémiologie de la coqueluche ainsi que les populations de B. Pertussis circulant dans la population humaine. Les premier vaccins introduit dans les 1950 et utilisés pour la primo vaccination et le rappel enfant, dit à germes entier
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4

Phillips, Linda Jane. "Immunization against Bordetella pertussis." Thesis, Kansas State University, 1985. http://hdl.handle.net/2097/9871.

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Smith, Maureen. "Studies on the modification of insulin secretion by pertussis vaccine and pertussis toxin." Thesis, University of Strathclyde, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303295.

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Smith, Colin J. "Genetic studies with Bordetella pertussis." Thesis, University of Glasgow, 1986. http://theses.gla.ac.uk/1505/.

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7

Lewandowski, Anna Zofia. "Antigenic variation in Bordetella pertussis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ60480.pdf.

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8

Sidey, Fiona M. "Metabolic effects of Bordetella pertussis." Thesis, University of Strathclyde, 1987. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=20352.

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The present work confirmed that B. pertussis infection or pertussis toxin produce hypoglycaemia in mice. The hypoglycaemia was associated with hyperinsulinaemia, and both were abolished by destruction of the pancreatic β cells with alloxan. Impaired glucose counterregulatory mechanisms may also contribute to pertussis-induced hypoglycaemia, as the hypoglycaemic action of insulin was prolonged in pertussis infected mice. On the other hand, impaired responsiveness to lower doses of insulin was found. Pertussis-induced hyperinsulinaemia had two components. First, the increase in serum insulin in
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9

Ladant, Daniel. "L'adenyl cyclase de bordetella pertussis." Paris 7, 1989. http://www.theses.fr/1989PA077200.

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Bordetella pertussis, l'agent de la coqueluche secrete une adenyl cyclase qui constitue l'un des principaux facteurs de virulence de cet organisme. Cet enzyme bacterien presente l'originalite d'etre active par la calmoduline, une proteine regulatrice eucaryote. Nous avons purifie l'adenyl cyclase a l'homogeneite; elle possede l'activite specifique la plus elevee connue pour cette classe d'enzymes. Elle est constituee d'une chaine polypeptidique de 43-50 kilodaltons qui fixe une molecule de calmoduline avec une grande affinite. Par proteolyse limitee du complexe adenyl cyclase/calmoduline, nous
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10

Goard, Jody Ruth. "An Ecological Perspective on Pertussis." ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2537.

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In 2012, 48,277 cases of pertussis were diagnosed in the United States. Pertussis, otherwise known as whooping cough, is a highly contagious, often debilitating, sometimes deadly, vaccine-preventable disease with an increasing incidence and death rate in the U.S, which may be due to vaccine exemptions. The purpose of this project was to determine if a relationship exists between immunization policies and immunization exemption rates, immunization exemption rates and pertussis rates, and immunization policies and pertussis rates in each state. Bronfenbrenner's bio-ecological framework was used
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11

GOYARD, SOPHIE. "Regulation de l'adenylcyclase de bordetella pertussis." Paris 6, 1993. http://www.theses.fr/1993PA066107.

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B. Pertussis, agent pathogene de la coqueluche, produit de nombreux facteurs de virulence dont la toxine adenylcyclase. Cet enzyme est active par une proteine eucaryote, la calmoduline ; particularite partagee avec une autre adenylcyclase bacterienne, celle de b. Anthracis, agent du charbon. Ces deux adenylcyclases comportent un motif peptidique hautement conserve que nous avons caracterise comme faisant partie du site catalytique de ces deux enzymes. Des anticorps diriges contre ce motif conserve nous ont permis de preciser une parente immunologique entre les deux adenylcyclases bacteriennes
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12

Tallett, April. "Structure and function of pertussis toxin." Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/20238.

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13

Advani, Abdolreza. "Epidemiological characterisation of Bordatella pertussis in Sweden, 1970-2004 /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-052-7/.

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14

del, Valle-Mendoza Juana, Wilmer Silva-Caso, Miguel Angel Aguilar-Luis, et al. "Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts." BioMed Central Ltd, 2018. http://hdl.handle.net/10757/624653.

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Objective: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them. Results: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-third of them were from infants between 2 and 3 months old. The most common symptoms were paroxysms of coughing (88.9%), difficulty breathing (72.2%), cyanosis (77.8%) and fever (50%). The mother was the most common symptomatic carrier (27.8%), followed by uncles/aunts (22.2%) among children with pertus
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15

Leusch, Mark Steven. "Purification and characterization of adenylate cyclase toxin from Bordetella pertussis." Diss., The University of Arizona, 1990. http://hdl.handle.net/10150/184998.

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Bordetella pertussis produces a number of virulence determinants believed to contribute to its survival in the host as well as to the pathogenesis of disease. One of these factors, adenylate cyclase toxin (ACT), has been implicated to penetrate human neutrophils and macrophages and abrogate their function by virtue of unregulated production of intracellular cAMP. In order to adequately study the nature of ACT and its role in pathogenesis, it is necessary to isolate the toxin from other virulence factors produced by the organism. Attempts by other investigators to purify ACT and maintain both i
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16

Seabrook, Richard N. "An immunochemical study of B. pertussis antigens." Thesis, Queen Mary, University of London, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279600.

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17

Craig, Frank Furlong. "Effects of Bordetella pertussis on neutrophil leukocytes." Thesis, University of Glasgow, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236023.

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18

Lobban, Margaret D. "The structure and function of pertussis toxin." Thesis, University of Edinburgh, 1990. http://hdl.handle.net/1842/19057.

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Cambuy, Diego Duque. "Epidemiologia genômica de Bordetella pertussis no Brasil." reponame:Repositório Institucional da FIOCRUZ, 2014. https://www.arca.fiocruz.br/handle/icict/13349.

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Made available in DSpace on 2016-03-28T12:41:00Z (GMT). No. of bitstreams: 2 diego_cambuy_ioc_mest_2014.pdf: 2689625 bytes, checksum: 9a0d86cf1fe73771c946b0bd687aec4b (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2015-04-14<br>Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil<br>A coqueluche, ou pertússis, é uma doença do trato respiratório causada principalmente pela bactéria Bordetella pertussis. Após 50 anos de vacinação, pertussis reemergiu, passando a ser a doença imunoprevinível mais frequente mesmo em pa
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20

Hayles, Elizabeth Helen. "The Maternal Pertussis Trial: Best practice for communication of perinatal pertussis booster recommendations and optimisation of the cocooning strategy." Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/15693.

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Pertussis, commonly known as ‘whooping cough’, is a respiratory infection caused by the bacterium Bordetella pertussis. Despite being a vaccine preventable disease, pertussis has remained largely endemic with recent epidemics causing significant morbidity and mortality. Worldwide, there is estimated to be 300 000 - 400 000 deaths due to pertussis each year (1).Whilst high global coverage of the primary childhood vaccine series has been achieved, infants too young to be vaccinated against pertussis remain susceptible. Subsequently, they bear the brunt of pertussis morbidity and mortality. A key
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21

Alhashmi, Ibrahim. "Live Metabolite-Deficient Bordetella pertussis: Determination of Suitability for use as a Vaccine in Humans using the Pertussis Mouse Model." Thesis, Curtin University, 2012. http://hdl.handle.net/20.500.11937/51705.

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This thesis embodies research that has demonstrated that there is strong case for further development of novel live attenuated metabolite deficient B pertussis vaccine such that it is non-toxic because it polarises the immune response of DTaP-vaccinated mice from Th2 to Th1 following booster vaccination with the live attenuated vaccine thus offering the chance of long term protection against whooping cough and disrupting the transmission from adolescents and adults to infants.
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22

Luo, Siding. "A Stochastic Model for the spread of Pertussis." Thesis, Uppsala University, Department of Mathematics, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-121728.

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23

Stenson, Trevor H. "Characterization of Bvg-repressed molecules of Bordetella pertussis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ34841.pdf.

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24

Glaser, Philippe. "Biologie moleculaire de l'adenylate cyclase de bordetella pertussis." Paris 6, 1988. http://www.theses.fr/1988PA066259.

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Bordella pertussis, agent etiologique de la coqueluche, synthetise, entre autres toxines, une adenylate cyclase dont l'activite depend d'une proteine de l'hote, la calmoduline. Clonage et structure du geni de l'adenylate cyclase (gene cya) ont ete realises par complementation d'une souche cya d escherichia coli, en reconstituant la bacterie l'activation par la calmoduline. L'adenylate cyclase et synthetisee sous forme d'un precurseur bifonctionnel de haut poids moleculaires
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25

Glaser, Philippe. "Biologie moléculaire de l'adénylate cyclase de Bordetella pertussis." Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb376139521.

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26

Torvaldsen, Siranda. "The epidemiology and prevention of pertussis in Australia." Thesis, The University of Sydney, 2001. http://hdl.handle.net/2123/808.

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Pertussis (whooping cough) remains an important public health problem in Australia. Although mortality and morbidity from pertussis declined dramatically following the introduction of mass vaccination programs in 1953, the level of morbidity remains unacceptably high for a vaccine-preventable disease. Aims and methods The primary aims of this thesis were (i) to ascertain the epidemiology of pertussis in Australia between 1993 and 2000 by analysing and interpreting sources of routinely collected data on pertussis; and (ii) to examine the effectiveness of vaccination against pertussis in a
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27

Torvaldsen, Siranda. "The epidemiology and prevention of pertussis in Australia." University of Sydney. Paediatrics and Child Health, 2001. http://hdl.handle.net/2123/808.

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Pertussis (whooping cough) remains an important public health problem in Australia. Although mortality and morbidity from pertussis declined dramatically following the introduction of mass vaccination programs in 1953, the level of morbidity remains unacceptably high for a vaccine-preventable disease. Aims and methods The primary aims of this thesis were (i) to ascertain the epidemiology of pertussis in Australia between 1993 and 2000 by analysing and interpreting sources of routinely collected data on pertussis; and (ii) to examine the effectiveness of vaccination against pertussis in a
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28

Neal, Shona Elaine. "Genotypic diversity and epidemiological typing of Bordetella pertussis." Thesis, University of Glasgow, 2004. http://theses.gla.ac.uk/30856/.

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The resurgence of pertussis in several highly vaccinated countries has stimulated this study of the genotypic diversity and epidemiological typing of Bordetella pertussis. The genotypic variation of B. pertussis was investigated in 318 UK clinical isolates from 1920-2002, vising pertactin (prnA) and pertussis toxin SI subunit (ptxA) gene typing. To date, the evaluation of typing methods used for B. pertussis has not been performed extensively. Therefore, in this thesis, the recognised methods, namely serotyping, pulsed-field gel electrophoresis (PFGE) using Xbal, and IS1002-RFLP analysis, were
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Dill, Michael T. "Characterization of the Aspartate Transcarbamoylase that is Found in the pyrBC’ Complex of Bordetella Pertussis." Thesis, University of North Texas, 2001. https://digital.library.unt.edu/ark:/67531/metadc3057/.

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An aspartate transcarbamoylase (ATCase) gene from Bordetella pertussis was amplified by PCR and ligated into pT-ADV for expression in Escherichia coli. This particular ATCase (pyrB) was an inactive gene found adjacent to an inactive dihydroorotase (DHOase) gene (pyrC'). This experiment was undertaken to determine whether this pyrB gene was capable of expression alone or if it was capable of expression only when cotransformed with a functional pyrC'. When transformed into E. coli TB2 pyrB-, the gene did not produce any ATCase activity. The gene was then co-transformed into E. coli TB2 p
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Nascimento, Ivan Pereira. "Expressão de antígenos de Bordetella pertussis em BCG Recombinante: subunidade 1 da toxina Pertussis e fragmento A da Hemaglutinina Filamentosa (FHA)." Universidade de São Paulo, 2002. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-15022016-163854/.

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O desenvolvimento de vacinas multivalente constitui urna das prioridades na pesquisa de vacinas modernas. A utilização de vetores vivos para apresentação de antígenos heterólogos mostra-se bastante atraente, e eliminaria a necessidade de várias doses para se alcançar uma proteção máxima. Este tipo de vacina poderia ser administrado em dose única, o que poderia aumentar a cobertura vacinal. Neste trabalho foi explorado o potencial do Mycobacterium bovis BCG recombinante (rBCG) vivo expressando antígenos de Bordetella pertussis, como futuro componente de urna vacina tetravalente rBCG-DTP contra
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31

Giayetto, Víctor O. "Caracterización de la infección por Bordetella spp. y coqueluche en la provincia de Córdoba." Master's thesis, Giayetto VO. Caracterización de la infección por Bordetella spp. y coqueluche en la provincia de Córdoba [Internet]. Universidad Nacional de Córdoba; 2015 [citado el 14 de febrero de 2020]. Disponible en: https://rdu.unc.edu.ar/handle/11086/6066, 2015. http://hdl.handle.net/11086/6066.

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Tesis - Maestría en Microbiología con Orientación en Investigación en Salud Humana - Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Secretaría de Graduados en Ciencias de la Salud, 2015<br>Fil: Giayetto, Victor Olegario. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Bacteriología y Virología Médica; Argentina.<br>Las enfermedades respiratorias, entre las que se encuentra coqueluche producida por Bordetella pertussis (Bp), son consideradas como la primera causa de mortalidad infantil en el mundo. Si bien la introducción de la vacuna produjo un marca
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Dupré, Elian. "La régulation de la virulence chez Bordetella pertussis : BvgS, modèle original de capteur de système à deux composants." Thesis, Lille 2, 2013. http://www.theses.fr/2013LIL2S022/document.

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La virulence de Bordetella pertussis, agent de la coqueluche, est liée à un arsenal de facteurs de virulence dont l’expression est régulée par le système à deux composants BvgAS. BvgA est le régulateur de réponse et BvgS le capteur du système, qui possède 3 domaines putatifs de perception de signaux. Il s’agit de 2 domaines périplasmiques « Venus FlyTrap » (VFT), reliés par un segment transmembranaire à un domaine PAS (Per-ARNT-Sim) cytoplasmique qui fait la jonction avec l’histidine-kinase. Les signaux perçus par ces domaines capteurs sont inconnus, mais une température de 37°C est suffisante
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Miller, Reginaldo Assad. "Desenvolvimento de metodologia in vitro para avaliação do fenômeno de sensibilização à histamina induzido pelo Toxina pertussis e vacina pertussis in vivo." reponame:Repositório Institucional da FIOCRUZ, 2008. https://www.arca.fiocruz.br/handle/icict/9265.

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Made available in DSpace on 2014-07-28T18:10:50Z (GMT). No. of bitstreams: 2 license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) 98.pdf: 3463846 bytes, checksum: 8603b620b9560561e10f307f624ab539 (MD5) Previous issue date: 2008<br>Made available in DSpace on 2014-12-22T16:56:35Z (GMT). No. of bitstreams: 2 98.pdf: 3463846 bytes, checksum: 8603b620b9560561e10f307f624ab539 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2008<br>Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde<br>Dentre
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Сміян, Олександр Іванович, Александр Иванович Смиян, Oleksandr Ivanovych Smiian та ін. "Епідемічна ситуація щодо кашлюка в м. Суми та Cумській області за 2001-2012 роки". Thesis, Сумський державний університет, 2013. http://essuir.sumdu.edu.ua/handle/123456789/32354.

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Захворюваність на кашлюк й досі залишається на досить високому рівні, не дивлячи на проведення обов’язкових профілактичних щеплень дитячому населенню. При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/32354
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35

Pavic, Espinoza Ivana, Medina Sandy Bendezu, Alzamora Angella Herrera, et al. "High prevalence of Bordetella pertussis in severe acute respiratory infections in hospitalized children under 5 years in Lima, Peru." Universidad Peruana de Ciencias Aplicadas (UPC), 2015. http://hdl.handle.net/10757/582376.

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ASTMH 64th Annual Meeting. October 25-29, 2015 Philadelphia Marriott Downtown Philadelphia, Pennsylvania USA<br>Acute respiratory infections (ARI) are the main cause of morbidity and mortality in children under 5 years worldwide. Bordetella pertussis is a highly contagious bacterium that can cause serious illness, and approximately half of infected infants less than 1 year old are hospitalized. Also, pertussis immunization series is not completed until six months of age, leaving young infants vulnerable to pertussis. In Peru, pertussis is an increasing health problem despite immunization eff
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36

Goode, Natasha Diane, and Natasha Diane Goode. "Assessment of Tdap Administration in the Third Trimester of Pregnancy." Diss., The University of Arizona, 2017. http://hdl.handle.net/10150/625597.

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Introduction: In 2012, the Advisory Committee on Immunization Practices (ACIP) of the Centers for Disease Control and Prevention expanded their recommendation for the Tdap vaccination to include the antepartum period. Regardless of immunization history, the recommendation states that medical practitioners should administer the Tdap vaccination to every pregnant woman in each occurring pregnancy (Munoz, et al., 2014; Shakib, et al., 2013; Goldfarb, Little, Brown, Riley, 2014). Methods: To describe treatment practices and uptake of Tdap vaccine, a cross-sectional descriptive survey design was u
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37

Tefon, Burcu Emine. "Towards Whole Cell Immunoproteome And Subproteomes Of Bordetella Pertussis." Phd thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12614238/index.pdf.

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Bordetella pertussis is a gram-negative, human pathogen and etiologic agent of whooping cough (pertussis), a highly contagious, acute respiratory illness. In this study, the analysis of whole immunproteome and subproteomes of this microorganism was performed. The soluble cytoplasmic proteomes of B. pertussis Tohama I strain and a local isolate Saadet were separated by 2DE. By Western blot analysis, we identified 25 immunogenic proteins of three categories. In the first group, there were well-known proteins of the pathogen The second group comprised proteins which were already shown antigenic i
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38

Graf, Anna. "Humorale und zelluläre Immunität nach Pertussis-Auffrischimpfung im Jugendalter." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-114881.

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39

Woldegeorgis, Fasil. "Analysis on seroepidemiology of pertussis, a multivariate statistical approach." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ36539.pdf.

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40

Demydchuk, Mykhaylo. "Structural investigation of the enzymatic mechanism of pertussis toxin." Thesis, Birkbeck (University of London), 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497793.

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41

Bokhari, Syed Habib. "Characterisation and secretion mechanism of Bordetella pertussis autotransporter proteins." Thesis, University of Glasgow, 2002. http://theses.gla.ac.uk/1507/.

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The identification and characterisation of new virulence determinants of 5. pertussis is providing important information for understanding the colonisation and survival strategies of the microorganism. B. pertussis deploys a range of surface-associated components to enable its successful colonisation of the host. Bap-5 has been identified as a new member of the B. pertussis autotransporter family of proteins that includes PRN, BrkA, TCF and Vag-8, largely due to its homology at the C-terminus and some other similar regions such as the RGD (integrin-binding) and SGXG (glycosaminoglycan-binding)
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42

Cahill, Edward Sean. "Antigen delivery systems for nasal immunisation against B. pertussis." Thesis, University of Nottingham, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321455.

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43

Funnell, Simon Gordon Paul. "Mechanisms of colonisation of mammalian tissues by Bordetella pertussis." Thesis, Open University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239726.

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Pearce, Alexandra M. "The structure and immunogenicity of fimbriae from Bordetella pertussis." Thesis, Open University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333436.

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Ernest, Lisa Lorene, and Lisa Lorene Ernest. "Pertussis Cocooning for Alaska: Development of an Educational Brochure." Diss., The University of Arizona, 2016. http://hdl.handle.net/10150/621034.

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Background and Significance: Pertussis infection rates have significantly increased in the United States even though pertussis is a vaccine preventable illness. Alaska has been significantly impacted by this disease and is ranked 3rd highest in the nation for infection rates per capita. Infants less than three months of age suffer the highest proportion of infections. The effects of pertussis are most severe in this age group, sometimes requiring hospitalization and causing death. One theorized contributing factor to the increased pertussis infection rates is the transition to an acellular per
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46

Bassinet, Laurence. "Bordetella pertussis et épithélium respiratoire : aspects biologiques et cliniques." Paris 12, 2004. https://athena.u-pec.fr/primo-explore/search?query=any,exact,990003948590204611&vid=upec.

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La coqueluche, infection des voies aériennes inférieures par Boedetella pertussis (Bp), est en recrudescence chez les adultes qui contaminent les nouveaux-nés exposés aux formes sévères de la maladie. Nous rapportons une épidémie de coqueluche parmi les membres du personnel soigant (MPS) d'un hôpital avec contamination de 2 patients adultes. Ces données font discuter une vaccination des MPS. Les interactions de l'hépithélium respiratoire humain avec Bp ont été étudiées dans le but initial de rechercher un réservoir bactérien chez l'adulte. Nous avons montré que Bp pénètre dans des cellules épi
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Bassinet, Laurence Guiso-Maclouf Nicole. "Bordetella pertussis et épithélium respiratoire aspects biologiques et cliniques /." Créteil : Université de Paris-Val-de-Marne, 2007. http://doxa.scd.univ-paris12.fr:8080/theses-npd/th0394859.pdf.

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Thèse de doctorat : Sciences de la vie et de la santé. Biologie cellulaire et moléculaires des épithéliums : Paris 12 : 2004.<br>Version électronique uniquement consultable au sein de l'Université Paris 12 (Intranet). Titre provenant de l'écran-titre. Bibliogr. : 332 réf.
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Van, der Ploeg Ingeborg. "Studies of G-protein coupled receptors using pertussis toxin." Stockholm : Kongl. Carolinska Medico chirurgiska Institutet, 1991. http://books.google.com/books?id=ks1pAAAAMAAJ.

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Dammers-Müller, Cirsten [Verfasser]. "Schwierigkeiten bei der Diagnostik der Pertussis / Cirsten Dammers-Müller." Köln : Deutsche Zentralbibliothek für Medizin, 2010. http://d-nb.info/1007193131/34.

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Hormozi, E. Kalantar. "Activation and immunogenicity of Bordetella pertussis adenylate cyclase toxin." Thesis, University of Glasgow, 1997. http://theses.gla.ac.uk/30948/.

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Adenylate cyclase toxin (CyaA) was produced and purified in the toxic CyaC-modified form and the unmodified non-toxic form from both B. pertussis and recombinant E. coli strains in sufficient quantity to allow large scale experimentation. Immunoblot analysis of crude and purified CyaA preparations revealed that the toxins were prepared as full length 200 kDa proteins with a small amount of degradation products of lower molecular weight protein in both toxic and non-toxic forms. The in vivo CyaC-modified CyaA toxin produced from recombinant E. coli showed comparable levels of cytotoxic and inva
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