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Artykuły w czasopismach na temat „Pharyngeal chlamydia”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 19 lutego 2022

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1

Andersen, Arthur A. "Comparison of Pharyngeal, Fecal, and Cloacal Samples for the Isolation of Chlamydia Psittaci from Experimentally Infected Cockatiels and Turkeys." Journal of Veterinary Diagnostic Investigation 8, no. 4 (October 1996): 448–50. http://dx.doi.org/10.1177/104063879600800407.

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Direct comparisons were made of Chlamydial isolation rates from pharyngeal swabs, fecal samples, and cloacal swabs from cockatiels and pharyngeal and cloacal swabs from turkeys experimentally infected with Chlamydia psittaci. During pathogenesis studies, 133 paired specimens were collected from cockatiels and 118 paired specimens were collected from turkeys. Of the 51 cockatiel Chlamydial infections detected, 80.4% were positive by the pharyngeal swab sample, 45.1% were positive by the fecal swab sample, and 37.3% were positive by the cloacal swab sample. Of the 87 turkey infections detected,

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2

Gaspari, Valeria, Antonella Marangoni, Antonietta D’Antuono, Greta Roncarati, Melissa Salvo, Claudio Foschi, and Maria Carla Re. "Pharyngeal Chlamydia and gonorrhea: a hidden problem." International Journal of STD & AIDS 30, no. 8 (May 2, 2019): 732–38. http://dx.doi.org/10.1177/0956462419838922.

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In this study we assessed the prevalence and predictors of pharyngeal infections due to Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) in a cohort of patients attending an STI Clinic. From January 2016 to September 2018, 893 patients attending the STI Clinic of St Orsola-Malpighi Hospital (Bologna, Italy) and reporting unprotected oral sex were enrolled. A pharyngeal swab for the molecular detection of CT and NG was collected from each patient. Positive CT samples were further genotyped by an omp1 gene PCR. A total of 134 cases of gonorrhea (15%) and 34 chlamydial infections (3.8%)

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Chan, Philip A., Ashley Robinette, Madeline Montgomery, Alexi Almonte, Susan Cu-Uvin, John R. Lonks, Kimberle C. Chapin, Erna M. Kojic, and Erica J. Hardy. "Extragenital Infections Caused byChlamydia trachomatisandNeisseria gonorrhoeae: A Review of the Literature." Infectious Diseases in Obstetrics and Gynecology 2016 (2016): 1–17. http://dx.doi.org/10.1155/2016/5758387.

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In the United States, sexually transmitted diseases due toChlamydia trachomatisandNeisseria gonorrhoeaecontinue to be a major public health burden. Screening of extragenital sites including the oropharynx and rectum is an emerging practice based on recent studies highlighting the prevalence of infection at these sites. We reviewed studies reporting the prevalence of extragenital infections in women, men who have sex with men (MSM), and men who have sex only with women (MSW), including distribution by anatomical site. Among women, prevalence was found to be 0.6–35.8% for rectal gonorrhea (media

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Lister, N. A., A. Smith, T. Read, and C. K. Fairley. "Testing men who have sex with men for Neisseria gonorrhoeae and Chlamydia trachomatis prior to the introduction of guidelines at an STD clinic in Melbourne." Sexual Health 1, no. 1 (2004): 47. http://dx.doi.org/10.1071/sh03005.

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Background: Guidelines for testing men who have sex with men (MSM) were published in 2002. They did not recommend asymptomatic screening for urethral gonorrhoea or pharyngeal screening for chlamydia. To determine if these guidelines were appropriate, we audited gonorrhoea and chlamydia testing of MSM at our centre. Methods: We carried out two audits at our Centre between August 2001 to July 2002. The first was an audit of testing MSM for gonorrhoea and/ or chlamydia over 12 days. The second was an audit of all positive tests over this 12-month period for gonorrhoea or chlamydia among MSM. Resu

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Goddard, Sian Louise, Preethi Rajagopal, and David James Templeton. "Increasing yield of pharyngeal Chlamydia trachomatis among male gay and bisexual clinic attendees in Sydney: an observational study." Sexual Health 14, no. 3 (2017): 282. http://dx.doi.org/10.1071/sh16181.

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Background The aim of the present study was to describe the temporal trends in Chlamydia trachomatis (CT) testing yield among gay and bisexual male (GBM) sexual health clinic attendees in Sydney. Methods: All CT testing occasions among GBM from January 2011 to December 2014 were reviewed. Yield was defined as the proportion of testing occasions where CT was detected. Results: In all, 2917 GBM were tested on 5445 occasions. CT was detected on 439 (8.1%; 95% confidence interval (CI) 7.4–8.8%) occasions. Pharyngeal, urethral and anorectal CT were detected on 74 (1.4%; 95% CI 1.1–1.7%), 109 (2.0%;

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6

Allan-Blitz, Lao-Tzu, Segundo R. Leon, Claire C. Bristow, Kelika A. Konda, Silver K. Vargas, Juan A. Flores, Brandon J. Brown, Carlos F. Caceres, and Jeffrey D. Klausner. "High prevalence of extra-genital chlamydial or gonococcal infections among men who have sex with men and transgender women in Lima, Peru." International Journal of STD & AIDS 28, no. 2 (July 10, 2016): 138–44. http://dx.doi.org/10.1177/0956462416630909.

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Chlamydia trachomatis and Neisseria gonorrhoeae are among the most common sexually transmitted bacterial infections in the world. Data are limited, however, on the burden of extra-genital chlamydial and gonococcal infections among men who have sex with men and transgender women in Lima, Peru. Data were gathered from self-collected anal or pharyngeal swabs from participants in Lima, Peru, and analyzed via cross-sectional methods. Prevalence ratios for the association between extra-genital infection with socio-demographic and sexual behaviors were determined. Overall, 127 (32.8%) participants ha

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7

Lister, Nichole A., Anthony Smith, and Christopher K. Fairley. "Introduction of screening guidelines for men who have sex with men at an STD clinic, the Melbourne Sexual Health Centre, Australia." Sexual Health 2, no. 4 (2005): 241. http://dx.doi.org/10.1071/sh05006.

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Background: A recent audit indicated that a substantial proportion of men who have sex with men (MSM) were not screened for rectal gonorrhoea and chlamydia at the Melbourne Sexual Health Clinic, Melbourne, Australia. In response, screening guidelines for MSM were introduced at the clinic using a computer reminder. The aim of this study was to evaluate the impact of the guidelines and alert on screening MSM for gonorrhoea and chlamydia. Methods: The medical records of MSM were reviewed for gonorrhoea and chlamydia screening by site (pharyngeal, urethral and rectal), four months before the imple

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8

Maynard, Michaela, Hector R. Nunez, Jun Tao, Madeline Montgomery, Alexi Almonte, Genoviva Sowemimo-Coker, Christina Chu, Collette Sosnowy, Philip Chan, and Philip Chan. "963. Extragenital Chlamydia and Gonorrhea Among Females Visiting an STD Clinic." Open Forum Infectious Diseases 6, Supplement_2 (October 2019): S29—S30. http://dx.doi.org/10.1093/ofid/ofz359.065.

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Abstract Background Rates of chlamydia (CT) and gonorrhea (GC) are increasing in the United States. Annual screening for urogenital infection is recommended for sexually active females less than 25 years and older females at risk. CT and GC can be detected at pharyngeal and rectal sites and are commonly asymptomatic. Currently, extragenital screening is only recommended in men who have sex with men (MSM). Data among females on extragenital CT and GC are limited. Methods We reviewed all females presenting to a sexually transmitted diseases (STD) clinic in Providence, Rhode Island from May 2014

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9

Karlsson, Andreas, Anders Österlund, and Annika Forssén. "Pharyngeal Chlamydia trachomatis is not uncommon any more." Scandinavian Journal of Infectious Diseases 43, no. 5 (February 7, 2011): 344–48. http://dx.doi.org/10.3109/00365548.2011.553243.

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10

Richardson, Daniel, Alice Pickering, Daniel Trotman, Kayleigh Nichols, Zoe Buss, John Devlin, and Fionnuala Finnerty. "Pharyngeal gonorrhoea in men who have sex with men." International Journal of STD & AIDS 32, no. 5 (February 3, 2021): 449–52. http://dx.doi.org/10.1177/0956462420975627.

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Pharyngeal gonorrhoea is important in the transmission dynamics of gonorrhoea, and generation of antimicrobial resistance and the performing of culture remains vital. We reviewed the notes of men who have sex with men (MSM) presenting to our clinic with a positive pharyngeal NAAT for gonorrhoea between January and December 2019. There were 383 cases of NAAT-positive pharyngeal gonorrhoea, and 28 (7%, 95% CI = 5.11–10.36) reported sore throat at presentation. Pharyngeal cultures were taken from 270/383 (70%), and 73/270 (27%) were culture positive with available antimicrobial sensitivities. Ove

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11

Jebakumar, S. P., C. Storey, M. Lusher, J. Nelson, B. Goorney, and K. R. Haye. "Value of screening for oro-pharyngeal Chlamydia trachomatis infection." Journal of Clinical Pathology 48, no. 7 (July 1, 1995): 658–61. http://dx.doi.org/10.1136/jcp.48.7.658.

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12

Chow, Eric P. F., Shayne Camilleri, Christopher Ward, Sarah Huffam, Marcus Y. Chen, Catriona S. Bradshaw, and Christopher K. Fairley. "Duration of gonorrhoea and chlamydia infection at the pharynx and rectum among men who have sex with men: a systematic review." Sexual Health 13, no. 3 (2016): 199. http://dx.doi.org/10.1071/sh15175.

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Background Chlamydia and gonorrhoea are the two most common sexually transmissible infections (STI) among men who have sex with men (MSM) worldwide. Infections at the pharynx and rectum are usually asymptomatic; however, the natural history of these infections remains unknown. The aim of this study is to estimate the duration of both infections at the extragenital sites from published epidemiological cohort studies. Methods: English peer-reviewed articles were searched from 1 January 2000 to 12 March 2015 in three electronic databases (MEDLINE, EMBASE and Cochrane Central). The prevalence-to-i

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13

Templeton, David J., Phillip Read, Rajesh Varma, and Christopher Bourne. "Australian sexually transmissible infection and HIV testing guidelines for asymptomatic men who have sex with men 2014: a review of the evidence." Sexual Health 11, no. 3 (2014): 217. http://dx.doi.org/10.1071/sh14003.

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Men who have sex with men (MSM) in Australia and overseas are disproportionately affected by sexually transmissible infections (STIs), including HIV. Many STIs are asymptomatic, so regular testing and management of asymptomatic MSM remains an important component of effective control. We reviewed articles from January 2009–May 2013 to inform the 2014 update of the 2010 Australian testing guidelines for asymptomatic MSM. Key changes include: a recommendation for pharyngeal chlamydia (Chlamydia trachomatis) testing, use of nucleic acid amplification tests alone for gonorrhoea (Neisseria gonorrhoe

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14

LI, L., M. LUTHER, K. MACKLIN, D. PUGH, J. LI, J. ZHANG, J. ROBERTS, B. KALTENBOECK, and C. WANG. "Chlamydia gallinacea: a widespread emerging Chlamydia agent with zoonotic potential in backyard poultry." Epidemiology and Infection 145, no. 13 (August 3, 2017): 2701–3. http://dx.doi.org/10.1017/s0950268817001650.

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SUMMARYChlamydia gallinacea, a new chlamydial agent, has been reported in four European countries as well as Argentina and China. Experimentally infected chickens with C. gallinacea in previous study showed no clinical signs but had significantly reduced gains in body weight (6·5–11·4%). Slaughterhouse workers exposed to infected chickens have developed atypical pneumonia, indicating C. gallinacea is likely a zoonotic agent. In this study, FRET-PCR confirmed that C. gallinacea was present in 12·4% (66/531) of oral–pharyngeal samples from Alabama backyard poultry. Phylogenetic comparisons based

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15

Vavala, Gabriella, Cameron Goldbeck, Claire C. Bristow, Chrysovalantis Stafylis, Paul C. Adamson, Dianna Polanco, Manuel A. Ocasio, et al. "Adolescents may accurately self-collect pharyngeal and rectal clinical specimens for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae infection." PLOS ONE 16, no. 9 (September 27, 2021): e0255878. http://dx.doi.org/10.1371/journal.pone.0255878.

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Background The COVID-19 pandemic illuminated the benefits of telemedicine. Self-collected specimens are a promising alternative to clinician-collected specimens when in-person testing is not feasible. In this study, we assessed the adequacy of self-collected pharyngeal and rectal specimens for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae among individuals undergoing chlamydia and gonorrhea screening. Methods We used data from a large cohort study that included male and female adolescents between the ages of 12–24 years. We considered self-collected specimens adequate for cl

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16

Winter, Andrew J., Gerry Gilleran, Kirstine Eastick, and Jonathan D. C. Ross. "Comparison of a Ligase Chain Reaction-Based Assay and Cell Culture for Detection of Pharyngeal Carriage ofChlamydia trachomatis." Journal of Clinical Microbiology 38, no. 9 (2000): 3502–4. http://dx.doi.org/10.1128/jcm.38.9.3502-3504.2000.

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In 264 genitourinary medicine clinic attenders reporting recent fellatio, the prevalence of pharyngeal Chlamydia trachomatis determined by an expanded standard including cell culture and two in-house PCR tests was 1.5% in 194 women and zero in 70 men. The ligase chain reaction (Abbott LCx) had a specificity of 99.2% and a positive predictive value of 60%.

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17

Manavi, K., N. Hettiarachchi, and J. Hodson. "Comparison of doxycycline with azithromycin in treatment of pharyngeal chlamydia infection." International Journal of STD & AIDS 27, no. 14 (July 11, 2016): 1303–8. http://dx.doi.org/10.1177/0956462415614723.

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Tipple, C., S. C. Hill, and A. Smith. "Is screening for pharyngeal Chlamydia trachomatis warranted in high-risk groups?" International Journal of STD & AIDS 21, no. 11 (November 2010): 770–71. http://dx.doi.org/10.1258/ijsa.2010.009494.

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Li, Kingbherly L., Jose Carlo B. Valencia, Florida F. Taladtad, Mary Grace T. Hernaez, Vivienne V. Luzentales, Cybele Lara R. Abad, and Edsel Maurice T. Salvana. "372. Prevalence of Urethral, Rectal, and Pharyngeal Gonorrhea and Chlamydia among Newly Diagnosed Filipino HIV Patients." Open Forum Infectious Diseases 6, Supplement_2 (October 2019): S195. http://dx.doi.org/10.1093/ofid/ofz360.445.

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Abstract Background The Philippines has the fastest-growing HIV epidemic in the Asia-Pacific. Concurrent sexually-transmitted infections increase the risk of HIV transmission and complications. The prevalence of Neisseria gonorrheae (NG) and Chlamydia trachomatis (CT) infection among Filipino HIV patients is unknown and screening is not universal. A symptom-based approach likely underestimates the prevalence of NG and CT among men who have sex with men (MSM). We determined the rectal, pharyngeal, and urethral prevalence of gonorrhea and chlamydia infection in our patient population using nucle

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Koedijk, F. D. H., J. E. A. M. van Bergen, N. H. T. M. Dukers-Muijrers, A. P. van Leeuwen, C. J. P. A. Hoebe, and M. A. B. van der Sande. "The value of testing multiple anatomic sites for gonorrhoea and chlamydia in sexually transmitted infection centres in the Netherlands, 2006–2010." International Journal of STD & AIDS 23, no. 9 (September 2012): 626–31. http://dx.doi.org/10.1258/ijsa.2012.011378.

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National surveillance data from 2006 to 2010 of the Dutch sexually transmitted infection (STI) centres were used to analyse current practices on testing extragenital sites for chlamydia and gonorrhoea in men who have sex with men (MSM) and women. In MSM, 76.0% and 88.9% were tested at least at one extragenital site (pharyngeal and/or anorectal) for chlamydia and gonorrhoea, respectively; for women this was 20.5% and 30.2%. Testing more than one anatomic site differed by STI centre, ranging from 2% to 100%. In MSM tested at multiple sites, 63.0% and 66.5% of chlamydia and gonorrhoea diagnoses,

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Latimer, Rosie Louise, Lenka Vodstrcil, Vesna De Petra, Christopher K. Fairley, Tim RH Read, Deborah Williamson, Michelle Doyle, Eric PF Chow, and Catriona Bradshaw. "Extragenital Mycoplasma genitalium infections among men who have sex with men." Sexually Transmitted Infections 96, no. 1 (June 19, 2019): 10–18. http://dx.doi.org/10.1136/sextrans-2019-054058.

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ObjectivesThere are limited data on the prevalence of Mycoplasma genitalium (Mgen) coinfection with rectal chlamydia (Chlamydia trachomatis (CT)) and rectal gonorrhoea (Neisseria gonorrhoeae (NG)) infections and few studies examining the prevalence of pharyngeal Mgen in men who have sex with men (MSM). Using transcription-mediated amplification assay, this study aimed to determine the proportion of rectal CT and rectal NG infections in MSM who are coinfected with rectal Mgen, and the proportion of MSM with Mgen detected in the pharynx in order to inform clinical practice.MethodsThis was a cros

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Hiransuthikul, Akarin, Rena Janamnuaysook, Thanthip Sungsing, Jureeporn Jantarapakde, Deondara Trachunthong, Steve Mills, Ravipa Vannakit, Praphan Phanuphak, and Nittaya Phanuphak. "High burden of chlamydia and gonorrhoea in pharyngeal, rectal and urethral sites among Thai transgender women: implications for anatomical site selection for the screening of STI." Sexually Transmitted Infections 95, no. 7 (April 13, 2019): 534–39. http://dx.doi.org/10.1136/sextrans-2018-053835.

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ObjectiveComprehensive data on Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections to guide screening services among transgender women (TGW) are limited. We studied the burden of CT/NG infections in pharyngeal, rectal and urethral sites of Thai TGW and determined missed CT/NG diagnoses if selected site screening was performed.MethodsThai TGW were enrolled to the community-led test and treat cohort. CT/NG screening was performed from pharyngeal swab, rectal swab and urine using nucleic acid amplification test. CT/NG prevalence in each anatomical site was analysed, along with th

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Tapsall, John, Phillip Read, Christopher Carmody, Christopher Bourne, Sanghamitra Ray, Athena Limnios, Theo Sloots, and David Whiley. "Two cases of failed ceftriaxone treatment in pharyngeal gonorrhoea verified by molecular microbiological methods." Journal of Medical Microbiology 58, no. 5 (May 1, 2009): 683–87. http://dx.doi.org/10.1099/jmm.0.007641-0.

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Diagnostic, genotypic and antibiotic-resistance determinants of Neisseria gonorrhoeae were analysed by molecular methods to verify the failure of ceftriaxone treatment in two cases of pharyngeal gonorrhoea. Monoplex assays were needed to define competitive inhibition of a positive Chlamydia PCR in a duplex assay. Different penA changes were detected in the N. gonorrhoeae isolated from the two cases. These were associated with raised ceftriaxone MICs of 0.03 and 0.016 mg l−1, which may have contributed to the treatment failures in these cases.

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Cosentino, Lisa A., Claire S. Danby, Lorna K. Rabe, Ingrid Macio, Leslie A. Meyn, Harold C. Wiesenfeld, and Sharon L. Hillier. "Use of Nucleic Acid Amplification Testing for Diagnosis of Extragenital Sexually Transmitted Infections." Journal of Clinical Microbiology 55, no. 9 (July 5, 2017): 2801–7. http://dx.doi.org/10.1128/jcm.00616-17.

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ABSTRACT Nucleic acid amplification testing (NAAT) is the preferred method to detect Chlamydia trachomatis and Neisseria gonorrhoeae , but no commercial tests are cleared by the U.S. Food and Drug Administration for use with extragenital swab samples. This study evaluated the performance of the Gen-Probe Aptima Combo2 assay (Aptima) and the Cepheid Xpert CT/NG assay (Xpert) to detect C. trachomatis and N. gonorrhoeae in rectal and pharyngeal samples from 224 men and 175 women reporting a history of anal receptive sexual intercourse. Discordant results between the NAATs were repeated using the

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Cope, A., W. Lo, and G. Kudesia. "Strand displacement amplification for Chlamydia trachomatis detection in rectal pharyngeal and eye swabs." Journal of Clinical Virology 36 (January 2006): S50. http://dx.doi.org/10.1016/s1386-6532(06)80893-0.

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Uehara, Shinya, Koichiro Wada, Ayano Ishii, Shinichi Sako, Toyohiko Watanabe, Koichi Monden, Toru Araki, and Hiromi Kumon. "PREVALENCE OF PHARYNGEAL CHLAMYDIA TRACHOMATIS AND NISSERIA GONORRHOEAE AMONG HETEROSEXUAL MEN IN JAPAN." Journal of Urology 181, no. 4S (April 2009): 64–65. http://dx.doi.org/10.1016/s0022-5347(09)60190-7.

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Wada, Koichiro, Shinya Uehara, Ritsuko Mitsuhata, Reiko Kariyama, Hiroyuki Nose, Ayano Ishii, Toyohiko Watanabe, et al. "Prevalence of pharyngeal Chlamydia trachomatis and Neisseria gonorrhoeae among heterosexual men in Japan." Journal of Infection and Chemotherapy 18, no. 5 (2012): 729–33. http://dx.doi.org/10.1007/s10156-012-0410-y.

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Árvai, Mariann, Eszter Ostorházi, Noémi Mihalik, Sarolta Kárpáti, and Márta Marschalkó. "Purulent keratoconjunctivitis due to Neisseria gonorrhoeae and Chlamydia trachomatis coinfection." Orvosi Hetilap 154, no. 21 (May 2013): 834–37. http://dx.doi.org/10.1556/oh.2013.29620.

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Gonococcal conjunctivitis is a rare infection induced by Neisseria gonorrhoeae and it usually manifests as a hyperacute purulent conjunctivitis. Ocular access of the infectious secretion during sexual intercourse is the way of transmission among adults. Inclusion conjunctivitis caused by the serovars D-K of Chlamydia trachomatis also affects the sexually active population. Authors present a case of a 33-year-old homosexual man who was treated for late latent syphilis formerly. Clinical symptoms were yellow purulent discharge for 3 weeks without any urological or upper respiratory tract symptom

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Straub, Diane M., and Angela Tetlow. "1538. Pilot Study of Self-collected Pharyngeal Testing for Chlamydia and Gonorrhea in the Setting of COVID19 Restrictions." Open Forum Infectious Diseases 7, Supplement_1 (October 1, 2020): S769. http://dx.doi.org/10.1093/ofid/ofaa439.1718.

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Abstract Background Given that many youth and young adults utilize multiple orifices during sexual activity, testing for STIs from multiple anatomical sites can increase rates of diagnosis. However, during the COVID pandemic, obtaining oral swabs by clinical staff was deemed an unacceptable COVID transmission risk and was discontinued in our clinic. To circumvent this obstacle to diagnosis, clinic staff developed a workaround of obtaining patient collected pharyngeal swabs for STI testing. This abstract reviews the results of this pilot intervention. Methods Patients presenting to an urban you

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Bristow, Claire C., Cristina Espinosa da Silva, Alicia H. Vera, Jesus E. Gonzalez-Fagoaga, Gudelia Rangel, and Heather A. Pines. "Prevalence of bacterial sexually transmitted infections and coinfection with HIV among men who have sex with men and transgender women in Tijuana, Mexico." International Journal of STD & AIDS 32, no. 8 (February 3, 2021): 751–57. http://dx.doi.org/10.1177/0956462420987757.

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We estimated the prevalence of syphilis and Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections, as well as human immunodeficiency virus (HIV) coinfection among cisgender men who have sex with cisgender men (MSM) and transgender women (TW) in Tijuana, Mexico. MSM and TW ( N = 212) recruited via respondent-driven and venue-based sampling for HIV testing underwent sexually transmitted infection (STI) testing and completed interviewer-administered surveys in this study (2017–2018). Treponemal rapid tests were used at the point-of-care with positives undergoing confirmatory testin

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Speers, David John, I.-Ly Joanna Chua, Justin Manuel, and Lewis Marshall. "Detection of Neisseria gonorrhoeae and Chlamydia trachomatis from pooled rectal, pharyngeal and urine specimens in men who have sex with men." Sexually Transmitted Infections 94, no. 4 (October 24, 2017): 293–97. http://dx.doi.org/10.1136/sextrans-2017-053303.

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ObjectivesScreening of men who have sex with men (MSM) for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) requires sampling from anorectal and pharyngeal sites in addition to urogenital sampling. Due to the cost of testing multiple anatomical sites individually testing of pooled specimens has potential merit. The Cepheid GeneXpert CT/NG assay (GeneXpert), which also has potential for point-of-care nucleic acid testing in the sexual health clinic, has not been assessed for pooled specimen testing.MethodsWe prospectively compared GeneXpert testing of pooled pharyngeal and rectal swabs

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Desclaux, Arnaud, Arabella Touati, Didier Neau, Cécile Laurier-Nadalié, Cécile Bébéar, Bertille de Barbeyrac, and Charles Cazanave. "Extra-rectal lymphogranuloma venereum in France: a clinical and molecular study." Sexually Transmitted Infections 94, no. 1 (July 11, 2017): 3–8. http://dx.doi.org/10.1136/sextrans-2017-053126.

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ObjectivesTo describe a series of extrarectal lymphogranuloma venereum (LGV) cases diagnosed in France.MethodsConsecutive LGV cases confirmed at the French Reference Centre for chlamydiae with an extrarectal sample from January 2010 to December 2015 were included. The first part of the study consisted of a retrospective case note review and analysis. In a second part, the complete ompA gene sequence of our samples was determined.ResultsThere were 56 cases overall: 50 cases of genital LGV and six cases of pharyngeal LGV. Subjects were all men, median age 39 years, 27/53 were HIV-positive, 47/51

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Hiransuthikul, Akarin, Thanthip Sungsing, Jureeporn Jantarapakde, Deondara Trachunthong, Stephen Mills, Ravipa Vannakit, Praphan Phanuphak, and Nittaya Phanuphak. "Correlations of chlamydia and gonorrhoea among pharyngeal, rectal and urethral sites among Thai men who have sex with men: multicentre community-led test and treat cohort in Thailand." BMJ Open 9, no. 6 (June 2019): e028162. http://dx.doi.org/10.1136/bmjopen-2018-028162.

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ObjectiveRoutine screening forChlamydia trachomatis(CT) andNeisseria gonorrhoeae(NG) infections in sexually exposed anatomical sites may be challenging in resource-limited settings. The objective of this study was to determine the proportion of missed CT/NG diagnoses if a single anatomical site screening was performed among men who have sex with men (MSM) by examining the pattern of anatomical sites of CT/NG infections.MethodsThai MSM were enrolled to the community-led test and treat cohort. Screening for CT/NG infections was performed from pharyngeal swab, rectal swab and urine using nucleic

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Bristow, Claire C., Sheldon R. Morris, Susan J. Little, Sanjay R. Mehta, and Jeffrey D. Klausner. "Meta-analysis of the Cepheid Xpert® CT/NG assay for extragenital detection of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections." Sexual Health 16, no. 4 (2019): 314. http://dx.doi.org/10.1071/sh18079.

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Background Most studies evaluating extragenital testing performance for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) detection by the Xpert® CT/NG show high per cent agreement with comparison assays; however, the precision around positive per cent agreement is low and thus the values that have been reported are not highly informative. Therefore, a systematic review was conducted and data from five studies were combined to better assess positive per cent agreement. Methods: The literature indexed on PubMed.gov was searched. Included studies were those that were an evaluation of the

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Badman, Steven G., Sara F. E. Bell, Judith A. Dean, Jime Lemoire, Luke Coffey, Joseph Debattista, Andrew M. Redmond, Owain D. Williams, Charles F. Gilks, and David M. Whiley. "Reduced sensitivity from pooled urine, pharyngeal and rectal specimens when using a molecular assay for the detection of chlamydia and gonorrhoea near the point of care." Sexual Health 17, no. 1 (2020): 15. http://dx.doi.org/10.1071/sh19028.

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Background The aim of this study was to compare the performance of pooled self-collected urogenital, pharyngeal and anorectal specimens to that of individual specimen results for the molecular detection of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) near the point of care (POC) for diagnostic sensitivity. Methods: Clients (mostly men who have sex with men) attending an urban community testing service and three sex-on-premises venues in Brisbane, Australia, were offered CT and NG testing by trained lay providers. Participants provided three self-collected specimens (urine, pharyng

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Caragol, Laura, Christopher Voegeli, Christie Mettenbrink, Karen Wendel, and Cornelis Rietmeijer. "Extragenital Gonorrhea and Chlamydia Testing Among Women Reporting Extragenital Exposure at an Urban STD Clinic: Is It Worth the Cost?" Open Forum Infectious Diseases 4, suppl_1 (2017): S104—S105. http://dx.doi.org/10.1093/ofid/ofx163.097.

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Abstract Background Current guidelines only recommend screening for gonorrhea (GC) and chlamydia (CT) at extragenital sites of exposure in men who have sex with men (MSM). With Medicaid reimbursement for GC/CT nucleic acid amplification testing (NAAT) at approximately $48/test, expanding testing to women requires a value assessment. We report the prevalence of extragenital GC/CT in women with extragenital exposure, determine the proportion of disease missed by urogenital NAAT, and estimate additional cost per infection identified by extragenital testing in women vs MSM. Methods We conducted a

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Beymer, Matthew R., Michelle A. DeVost, Robert E. Weiss, Rhodri Dierst-Davies, Chelsea L. Shover, Raphael J. Landovitz, Corinne Beniasians, et al. "Does HIV pre-exposure prophylaxis use lead to a higher incidence of sexually transmitted infections? A case-crossover study of men who have sex with men in Los Angeles, California." Sexually Transmitted Infections 94, no. 6 (February 27, 2018): 457–62. http://dx.doi.org/10.1136/sextrans-2017-053377.

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BackgroundPre-exposure prophylaxis (PrEP) is an effective method for reducing HIV incidence among at-risk populations. However, concerns exist over the potential for an increase in STIs following PrEP initiation. The objective of this study is to compare the STI incidence before and after PrEP initiation within subjects among a cohort of men who have sex with men in Los Angeles, California.MethodsThe present study used data from patients who initiated PrEP services at the Los Angeles LGBT Center between October 2015 and October 2016 (n=275). A generalised linear mixed model was used with a cas

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Munson, Erik, David Wenten, Sheila Jhansale, Mary Kay Schuknecht, Nicki Pantuso, Joshua Gerritts, Aaron Steward, Kimber L. Munson, Maureen Napierala, and Deb Hamer. "Expansion of Comprehensive Screening of Male Sexually Transmitted Infection Clinic Attendees with Mycoplasma genitalium and Trichomonas vaginalis Molecular Assessment: a Retrospective Analysis." Journal of Clinical Microbiology 55, no. 1 (September 14, 2016): 321–25. http://dx.doi.org/10.1128/jcm.01625-16.

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ABSTRACTOf 1,493 encounters of males at a sexually transmitted infection (STI) clinic in a community with a high prevalence of STI,Chlamydia trachomatiswas detected in 8.7% andNeisseria gonorrhoeaewas detected in 6.6%. AdditionalTrichomonas vaginalisandMycoplasma genitaliumscreening found 17.4% and 23.9% of the encounters, respectively, to be positive for STI. STI agents were detected in 13.7% of urine specimens; addition of pharyngeal and rectal collections to the analysis resulted in detection of STI agents in 19.0% and 23.9% of encounters, respectively. A total of 101 (23.8%) encounters of

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Winceslaus, S. J. "Response to Tipple et al: Is screening for pharyngeal Chlamydia trachomatis warranted in high-risk groups?" International Journal of STD & AIDS 22, no. 7 (July 2011): 419. http://dx.doi.org/10.1258/ijsa.2011.011061.

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Wikström, Arne, Maria Rotzén-Östlund, and Lena Marions. "Occurrence of pharyngeal Chlamydia trachomatis is uncommon in patients with a suspected or confirmed genital infection." Acta Obstetricia et Gynecologica Scandinavica 89, no. 1 (January 2010): 78–81. http://dx.doi.org/10.3109/00016340903370130.

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Rooijen, M. S. van, N. Nassir, R. Bom, H. J. C. de Vries, S. Bruisten, and A. P. van Dam. "P3.271 Identical Multilocus Sequence Typing (MLST) Analysis in Sequential Samples from Patients with Pharyngeal Chlamydia Infections." Sexually Transmitted Infections 89, Suppl 1 (July 2013): A233.2—A233. http://dx.doi.org/10.1136/sextrans-2013-051184.0727.

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Allan-Blitz, Lao-Tzu, Kelika A. Konda, Gino M. Calvo, Silver K. Vargas, Segundo R. Leon, Eddy R. Segura, Carlos F. Caceres, and Jeffrey D. Klausner. "High incidence of extra-genital gonorrheal and chlamydial infections among high-risk men who have sex with men and transgender women in Peru." International Journal of STD & AIDS 29, no. 6 (November 29, 2017): 568–76. http://dx.doi.org/10.1177/0956462417744098.

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Extra-genital Neisseria gonorrhoeae and Chlamydia trachomatis infections are associated with antimicrobial resistance and HIV acquisition. We analyzed data from a cohort of men who have sex with men (MSM) and transgender women followed quarterly for two years in Peru. Incident cases were defined as positive N. gonorrhoeae or C. trachomatis nucleic acid tests during follow-up. Repeat positive tests were defined as reinfection among those with documented treatment. We used generalized estimating equations to calculate adjusted incidence rate ratios (aIRRs). Of 404 participants, 22% were transgen

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Park, Jason, Julia L. Marcus, Mark Pandori, Ameera Snell, Susan S. Philip, and Kyle T. Bernstein. "Sentinel Surveillance for Pharyngeal Chlamydia and Gonorrhea Among Men Who Have Sex With Men—San Francisco, 2010." Sexually Transmitted Diseases 39, no. 6 (June 2012): 482–84. http://dx.doi.org/10.1097/olq.0b013e3182495e2f.

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Peters, Remco P. H., Jan Henk Dubbink, Lisette van der Eem, Stephan P. Verweij, Myrte L. A. Bos, Sander Ouburg, David A. Lewis, Helen Struthers, James A. McIntyre, and Servaas A. Morré. "Cross-Sectional Study of Genital, Rectal, and Pharyngeal Chlamydia and Gonorrhea in Women in Rural South Africa." Sexually Transmitted Diseases 41, no. 9 (September 2014): 564–69. http://dx.doi.org/10.1097/olq.0000000000000175.

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Jenkins, Wiley D., Laurette L. Nessa, and Ted Clark. "Cross-sectional study of pharyngeal and genital chlamydia and gonorrhoea infections in emergency department patients: Table 1." Sexually Transmitted Infections 90, no. 3 (December 23, 2013): 246–49. http://dx.doi.org/10.1136/sextrans-2013-051358.

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Papp, John R., Katherine Ahrens, Christi Phillips, Charlotte K. Kent, Susan Philip, and Jeffrey D. Klausner. "The use and performance of oral–throat rinses to detect pharyngeal Neisseria gonorrhoeae and Chlamydia trachomatis infections." Diagnostic Microbiology and Infectious Disease 59, no. 3 (November 2007): 259–64. http://dx.doi.org/10.1016/j.diagmicrobio.2007.05.010.

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Voirin, Nicolas, Camille Allam, Caroline Charre, Christine Fernandez, Matthieu Godinot, Fatima Oria, Aymeric Pansu, Christian Chidiac, Hélène Salord, and Laurent Cotte. "Optimizing Strategies for Chlamydia trachomatis and Neisseria gonorrhoeae Screening in Men Who Have Sex With Men: A Modeling Study." Clinical Infectious Diseases 70, no. 9 (June 14, 2019): 1966–72. http://dx.doi.org/10.1093/cid/ciz510.

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Abstract Background International guidelines recommend the systematic screening for Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) infections in all men who have sex with men (MSM) who have engaged in unprotected sex. However, the optimal screening strategy remains unclear. We developed a modeling approach to optimize NG/CT screening strategy in MSM. Methods A compartmental model of NG/CT screening and infection was implemented. NG/CT anal, pharyngeal, and urine (APU) samples from MSM attending the sexually transmitted infections clinic were used to estimate the screening rate, prev

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Crosby, Richard A., Laura F. Salazar, Brandon Hill, and Leandro Mena. "A comparison of HIV-risk behaviors between young black cisgender men who have sex with men and young black transgender women who have sex with men." International Journal of STD & AIDS 29, no. 7 (January 19, 2018): 665–72. http://dx.doi.org/10.1177/0956462417751811.

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This study compared sexually transmitted infection (STI)-associated risks between young Black cisgender men who have sex with men (YBMSM) and young Black transwomen who have sex with men (YBTWSM). Comparisons pertained to: (1) prevalence of infections; (2) sexual risk; (3) partner-related risks; and (4) socioeconomic marginalization. YBMSM (n = 577) and YBTWSM (n = 32) were recruited from an STI clinic in the USA. Volunteers completed a computer-assisted self-interview and medical records were abstracted for STI/HIV information. Significantly greater prevalence of pharyngeal Chlamydia ( P <

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KESSLER, HARALD H., KAREN PIERER, DORIS STUENZNER, PIET AUER-GRUMBACH, EVA-MARIA HALLER, and EGON MARTH. "Rapid Detection of Chlamydia trachomatis in Conjunctival, Pharyngeal, and Urethral Specimens With a New Polymerase Chain Reaction Assay." Sexually Transmitted Diseases 21, no. 4 (July 1994): 191–95. http://dx.doi.org/10.1097/00007435-199407000-00002.

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Hamasuna, Ryoichi, Tetsuro Matsumoto, Ryoichi Hamasuna, Satoshi Takahashi, Shinya Uehara, Tetsuro Matsumoto, Satoshi Takahashi, and Shinya Uehara. "Should urologists care for the pharyngeal infection of Neisseria gonorrhoeae or Chlamydia trachomatis when we treat male urethritis?" Journal of Infection and Chemotherapy 18, no. 3 (2012): 410–13. http://dx.doi.org/10.1007/s10156-011-0355-6.

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