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Rozprawy doktorskie na temat „PhD Anatomy”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Abualhin, Mohammad <1987&gt. "Does Aorto-Iliac Anatomy Affect Endovascular Aortic Aneurysm Repair Durability With The New Generation Endografts?" Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amsdottorato.unibo.it/9611/1/PhD%20Thesis.%20Abualhin%20Final.pdf.

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Introduction: Endovascular aneurysm repair(EVAR) has become the main treatment for abdominal aortic aneurysm(AAA). Anatomical features of the AAA are pivotal in EVAR success. The aim of this study was to evaluate known anatomical features as risk factors for the freedom from reintervention(FFR) taking into account the new-generation endografts. Materials and Methods: This study was a retrospective monocentric study including consecutive patients treated by EVAR from 2012 to 2018 in elective setting. All currently reported anatomic factors including aortic neck and iliac arteries proprieti

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Landorf, Karl B. "Effectiveness of foot orthoses in the treatment of plantar fasciitis." Thesis, View thesis, 2004. http://handle.uws.edu.au:8081/1959.7/696.

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The aim of this thesis is to evaluate the short and long term effectiveness of foot orthoses in the treatment of plantar fasciitis.Three studies were undertaken, the first two informing the third. The aim of the first study was to establish prescription habits of Australian and New Zealand podiatrists in order to ascertain the most commonly prescribed foot orthoses. The second study was conducted to establish the most appropriate outcome measure to assess the effectiveness of foot orthoses in the treatment of plantar faciitis. The main study, a pragmatic single-blind randomised control trial,

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3

McNamara, Diana L. "The anatomy of an environmental decision : the case of recycling." Thesis, University of Aberdeen, 2015. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=228206.

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The human race has always faced environmental challenges. What differs at present, however, are the scale and entrenched social structures (e.g., capitalism, man/nature duality, a dominant social paradigm) that are contributing to these problems and our own irrationality when it comes to possible solutions. Implicit testing methodologies, borrowed from experimental psychology, may be able to bypass some of these issues and provide a means to identify simple 'point of decision' interventions to effect change in behavior on an individual level. The approach adopted in the current thesis was to e

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4

Bollmann, Christof. "Quantification of intact quadriceps tendon, and suprapatellar fat pad : MR-arthrography, anatomy, and cryosections in the sagittal plane /." [S.l.] : [s.n.], 2000. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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Ditschun, Tanya Louise. "6-n-Propylthiouracil (PROP) taster status determination and its relation to tongue anatomy, food liking and intake /." Connect to Digital dissertations. Restricted to UC campuses. Access is free to UC campus dissertations, 2002. http://uclibs.org/PID/11984.

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Vase, Hollie Francesca. "Interrogating therapeutic manipulation of the endocannabinoid system in the human colon." Thesis, University of Aberdeen, 2013. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=203798.

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The endocannabinoid system (ECS) is known to be involved in key aspects of cell maintenance within the human colon, as well as being dysregulated in pathophysiological conditions, including colon inflammation and cancer. However, the contribution of the ECS within each of these conditions has not been fully elucidated. This indicates that the current identification of key targets within the ECS that are involved in gut pathology could be used as potential novel therapeutics. Two experimental approaches were designed and optimised to give an insight into ECS signal regulation within the human c

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Fernandes, Patricio Tatiana Marisa <1987&gt. "Novel, Bio-Inspired Superparamagnetic Hybrid Microspheres for Bone Tissue Engineering." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amsdottorato.unibo.it/7906/1/PhD%20thesis_Tatiana%20Patr%C3%ADcio.pdf.

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The available strategies for the treatment of complex bone defects are limited and do not effectively promote bone tissue regeneration. Smart biomaterials have been investigated and designed as a suitable tool for application in degenerative diseases. In particular, magnetic materials are a class of smart biomaterials that showed promising results in bone tissue regeneration or as a diagnostic use. Therefore, the development of biomaterials with magnetic properties is an emerging field of research. The present work describes the application of biomineralisation process, to develop novel biocom

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Ghetti, Martina <1988&gt. "New Frontiers of Skin Tissue Engineering: from the Laboratory to Clinical Practice." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amsdottorato.unibo.it/8061/1/PhD%20thesis%20Martina%20Ghetti.pdf.

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This thesis is focused on the key role of extracellular matrix in skin tissue engineering. Firstly, I presented three dimensional structures derived through the physiological secretion of extracellular matrix (ECM), that may be a bioinspired scaffold. I performed a biological characterization of cell-assembled ECMs from three different sub-populations of skin fibroblasts; papillary fibroblasts (Pfi), reticular fibroblasts (Rfi), and dermal papilla fibroblasts (DPfi). Fibroblast sub-populations were cultured with ascorbic acid to promote cell-assembled matrix production for 10 days. Cells were

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9

Alnabulsi, Abdo. "Identification and characterisation of novel protein biomarkers for colorectal cancer prognosis." Thesis, University of Aberdeen, 2018. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=237661.

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Thomson, Alison Kathryn. "Organ developmental and maturational defects in Spinal Muscular Atrophy." Thesis, University of Aberdeen, 2016. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=231849.

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Spinal Muscular Atrophy (SMA), traditionally described as a predominantly childhood form of motor neuron disease, is a leading genetic cause of infant mortality. Although motor neurons are undoubtedly the primary affected cell type, SMA is now widely recognised as a multisystem disorder, where a variety of organs and systems in the body are also affected. Vascular perfusion abnormalities have previously been reported in both patients and mouse models of SMA, however it remains unclear whether these defects are secondary to the motor neuron pathology for which this disease is known. Through ana

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11

Nadal, Catala Gema. "The differential ability of methylated folate and folic acid to maintain DNA stability and normal characteristics in human colon cells in vitro." Thesis, University of Aberdeen, 2017. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=231796.

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Folates are water-soluble B vitamins, which maintain DNA stability by regulating nucleotide synthesis and DNA methylation. Folates influence CRC risk and their ability to prevent or promote carcinogenesis may be dependent on several variables here investigated. No in vitro study has yet modelled the physiological folate status that human colon cells are exposed to in vivo. This study evaluates the ability of different forms and concentrations of folate to maintain DNA stability and normal cell function in folate-sufficient and stable human colonocytes and to modify DNA instability and the acqu

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12

Alsaid, Bayan. "L’innervation intra-pelvienne : étude anatomique et immuno-histochimique avec reconstruction tridimensionnelle." Thesis, Paris 11, 2011. http://www.theses.fr/2011PA11T015.

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Introduction : L’utilisation des méthodes anatomiques classiques rend difficile la localisationprécise des micro-fibres nerveuses et ne permet pas de déterminer leur nature ni leur fonction.La chirurgie pelvienne est associée à des séquelles urinaires et sexuelles fréquentes causéespar lésion iatrogène des nerfs pelviens. La connaissance de l’anatomie et de la physiologie del’innervation intra-pelvienne est fondamentale pour tenter de réduire le taux de troublesfonctionnels postopératoires.Objectifs : i) étudier l’anatomie topographique et la nature de fibres nerveuses intrapelvienneen utilisa

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Basavaraju, Umesh. "Inflammatory biomarkers of colorectal neoplasia and their manipulation by an anti-inflammatory diet." Thesis, University of Aberdeen, 2011. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=182290.

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Colorectal neoplasia (CRN) continues to be a leading cause of morbidity and mortality in the developed world and with westernisation, similar trends are now emerging in the developing world. Although secondary prevention through screening programmes has reduced mortality, uptake remains poor due to the invasive nature of colonoscopy, which also exerts increased costs to the health care system. Primary prevention remains the ultimate aim to reduce the morbidity and mortality associated with CRN. In this regard, chemoprevention strategies through regular use of aspirin and other NSAIDS have show

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Diamond, Alexandra Jane. "An investigation into the roles of slits and roundabouts during vertebrate limb development." Thesis, University of Aberdeen, 2016. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=231142.

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Slits and their Roundabout (Robo) receptors were identified based on their role in regulating axon guidance, but are known to play multiple roles in development, including regulating heart development and myoblast migration. There are 3 vertebrate Slits (Slit1 – 3) and 4 Robos (Robo1 – 4), and previous work has demonstrated expression of Slit and Robo family members in and around developing joints where their function is unclear. Mutations in human Robo3 have been linked to degenerative joint disorders, such as scoliosis and rheumatoid arthritis. Misregulation of other members of the Slit/Robo

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15

Thapa, Dinesh. "Studies on the influence of essential oils on human gut bacteria and colonic cells." Thesis, University of Aberdeen, 2015. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=225962.

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The ability of essential oils (EO) to manipulate the intestinal microbiota may potentiate their application in food as nutraceutical and as prophylactic agents for colonic disease. Little is known about the influence of EO on gut bacteria, the mechanism of their antibacterial action and genotoxicity to the host. Here, the antibacterial activities of EO in pure and in a mixed faecal culture were investigated. These antibacterial activities were further studied to compare the selective nature of EO and their effects on membrane integrity. The growth of gut pathogens and commensals was inhibited

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16

Xian, Jie <1989&gt. "From clinic to laboratory: Signal transduction analysis and future applications." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amsdottorato.unibo.it/9535/1/PHD%20Thesis%20Jie%20Xian%20new%20.pdf.

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Abstract Background: Epithelioid hemangioma (EH) of bone is a vascular neoplasm with a ubiquitous distribution, including bone and soft tissue. The clinical behavior of EH is complicated because of its multifocal presentation and rare lymph node involvement. To date, up to 25% EH of bone presents synchronous bone lesions and specific gene alterations. Recently, a novel and recurrent FOS gene rearrangement was present in nearly one third of EH across a variety of locations. Before the discovery of gene rearrangements specific to this rare entity, EH was often misdiagnosed as epithelioid hemang

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17

Garner, Austin Michael. "Examining the Relationships between Form, Function, Environment, and Behavior in Adhesive Pad-bearing Lizards." University of Akron / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=akron1626363948177358.

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Saunders, Fiona R. "An investigation of non-steroidal anti-inflammatory drug mediated modulation of the polyamine pathway in an in vitro model of colorectal cancer." Thesis, University of Aberdeen, 2008. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=53328.

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Our hypothesis is that the polyamine biosynthetic pathway, a pathway essential in many cellular functions, is modulated by NSAIDs and that this is, at least in part, how NSAID chemoprevention is mediated. An <i>in vitro </i>model of colorectal cancer was used: two cell lines one of which is COX positive and one COX negative to determine the effects of a range of selective and non-selective NSAIDs on various reactions within the polyamine pathway. NSAIDs are cytotoxic to colorectal cancer cells regardless of their COX expression. NSAID-mediated inhibition of cell growth is accompanied by inhi

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Almulhim, Zayed. "Imaging hypoxia in colorectal cancer and gastroesophageal cancer with positron emission tomography." Thesis, University of Aberdeen, 2017. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=232243.

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Purpose: Hypoxia in colorectal cancer (CRC) and gastroesophageal cancer (GEC) decreases tumour responsiveness to radio and chemotherapy leading to cancer progression and poor prognosis. This is the first study to utilise [18F]FAZA hypoxia radiotracer in patients with CRC and GEC. Methods: Six patients (mean age 68±8 years, 2 males and 4 females) with CRC and 4 patients diagnosed with GEC (mean age 65 years, 3 males and 1 female) were included in the study. [18F]FAZA was synthesised at the John Mallard Scottish PET Centre. After injection with 370 MBq of [18F]FAZA, PET/CT images with 60 min dyn

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Keller, Elizabeth Greer. "Novel chemotherapeutics against lung and colon cancer." Click here for download, 2010. http://proquest.umi.com.ps2.villanova.edu/pqdweb?did=1961333981&sid=1&Fmt=2&clientId=3260&RQT=309&VName=PQD.

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21

Obradors, Cherta Albert. "Anàlisi completa d'aneuploïdies d'origen femení i de malalties monogèniques en embrions: el diagnòstic genètic preimplantacional de doble factor (DF-PGD)." Doctoral thesis, Universitat Autònoma de Barcelona, 2009. http://hdl.handle.net/10803/3820.

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El Diagnòstic Genètic Preimplantacional (o DGP) és un conjunt de metodologies, que s'apliquen en el transcurs d'un cicle de reproducció assistida, i que permeten la selecció d'embrions sans en parelles afectes de malalties genètiques hereditàries com la fibrosi quística o l'hemofília, entre moltes altres.<br/>A més, també s'utilitza per realitzar un cribatge d'alteracions cromosòmiques (o aneuploïdies) que puguin afectar l'embrió, ja que s'ha evidenciat que aquestes són molt abundants en avortaments. S'ha postulat que una selecció positiva dels embrions lliures de aneuploïdies (és a dir, euplo

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22

Phyu, Su Myat. "Targeting of the PI3K/AKT/mTOR signalling pathway and associated kinases in breast and colon cancer cells and response evaluation by molecular imaging techniques." Thesis, University of Aberdeen, 2018. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=238576.

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The phosphatidylinositol-3-kinase/AKT (Protein Kinase B)/mammalian target of rapamycin (PI3K/AKT/mTOR) signalling pathway, downstream of tyrosine kinase receptors, is upregulated in human cancers including breast and colon cancers. Glycogen synthase kinase 3 (GSK 3) is a serine/threonine protein kinase plays important role in various cellular processes including glycogen synthesis mediated by insulin signalling pathway. Moreover, 5' adenosine monophosphate activated protein kinase (AMPK), a crucial cellular energy sensor, has regulatory role in cell growth and proliferation through mTOR pathwa

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Ogren, Jennifer Anne. "Mapping anatomic correlates of pathological activity in the epileptic human hippocampus." Diss., Restricted to subscribing institutions, 2008. http://proquest.umi.com/pqdweb?did=1666117471&sid=3&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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FERRI, NICOLETTA. "EMBODIED TEACHING: PROSPETTIVE DI RICERCA A SCUOLA ATTRAVERSO L'ANATOMIA ESPERIENZIALE." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2018. http://hdl.handle.net/10281/241227.

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Questo lavoro di ricerca nasce dal desiderio di indagare il potenziale riflessivo, euristico e trasformativo della dimensione embodied nei processi di insegnamento/apprendimento. Per farlo ha interrogato un gruppo di insegnanti della scuola primaria, coinvolgendole in una ricerca partecipativa sulle proprie pratiche di insegnamento e sul loro modo unico di incarnarle (embodied teaching), a partire da un’attivazione corporea specifica (Anatomia Esperienziale). La mia domanda di ricerca si è orientata in due direzioni. Ad un livello metodologico potrebbe essere formulata nel seguente modo: come

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Cheng, Bo. "Passive rotational damping in flapping flight." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 89 p, 2009. http://proquest.umi.com/pqdweb?did=1889090361&sid=9&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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Chellappa, Karthikeyani. "Functional analysis of Tyrosine residues in human hepatocyte nuclear factor 4alpha." Diss., UC access only, 2009. http://proquest.umi.com/pqdweb?index=72&did=1790348311&SrchMode=1&sid=1&Fmt=7&retrieveGroup=0&VType=PQD&VInst=PROD&RQT=309&VName=PQD&TS=1270229827&clientId=48051.

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Thesis (Ph. D.)--University of California, Riverside, 2009.<br>Includes abstract. Includes bibliographical references (leaves 293-348). Issued in print and online. Available via ProQuest Digital Dissertations.

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Shojaeian-Zanjani, Mohammad-Hadi. "Etude en cytologie quantitative de l'olive bulbaire des rongeurs : relation entre mort neuronale et elimination synaptique au cours du developpement et role des cellules cibles dans la regulation du nombre des neurones olivaires." Paris 6, 1987. http://www.theses.fr/1987PA066211.

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"Atypical anatomy in children and adults with persistent developmental stuttering." Tulane University, 2007.

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A larger right prefrontal and a larger left occipital lobe (lobar asymmetry) and a larger left planum temporale (PT) are consistent asymmetries found in the human brain. Reduced or reversed asymmetries from these typical configurations are considered atypical and may be markers of atypical function. Atypical lobar and PT asymmetries have been found in adults with persistent developmental stuttering (PDS). These atypical asymmetries may represent a neural risk for developing PDS. To further understand the development of these asymmetries; volumes, ratios and asymmetry quotients were investigate

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"Sex differences in the anatomy of human perisylvian regions: Frontal and temporal cortical language areas." Tulane University, 2003.

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The left hemisphere plays a predominant role in speech-language functions. Anatomical asymmetries of perisylvian speech-language regions have been found with evidence that leftward asymmetries are associated with language dominance. There is also evidence that sex-linked differences in the functional organization of language exist, although sex-linked anatomical differences have not been extensively studied and results have been conflicting. For example, developmental language disorders are male predominate, and women may have more bilaterally represented language functions. Given the controve

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"Mechanics and quantitative morphology of the carotid baroreceptor region of normotensive and spontaneously hypertensive rats." Tulane University, 1987.

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An in vivo mechanical analysis and a detailed quantitative morphological study of the arteries in the carotid baroreceptor region from normotensive (NTR) and spontaneously hypertensive (SHR) adult (9-10 month old) male rats were completed The morphological studies incorporated a newly developed vascular perfusion technique (Engle and Kirby, 1986) that allowed for the preservation of vascular dimensions at distending pressures equivalent to the physiological mean arterial pressures (PMAP) obtained under normal resting conditions for each individual animal. The following changes in the carotid a

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"Corticotropin-releasing factor and dopamine in the central amygdaloid nucleus of the rat: Localization and interactions." Tulane University, 1990.

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Light microscopic immunocytochemistry (ICC) of the central nucleus (CA) of the rat amygdaloid complex revealed two populations of corticotropin releasing factor (CRF) immunoreactive (IR) neuronal perikarya and terminals. Perikarya were isolated within the centrolateral (CL) subdivision of the CA (76.6% of all CRF-IR perikarya in the CA) and the centromedial subdivision of the CA (23.4% of total). CRF-IR fibers were occasionally observed within the stria terminals (ST) while a dense population of CRF-IR terminals was located in the central lateral capsular (CLC) subdivision of CA. In the CLC, C

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"Expression of an estrogen receptor variant with transcriptional regulatory activity in human breast cancer cell lines: A possible model system for the development of hormone resistance." Tulane University, 1993.

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Accurate identification of prognostic markers in primary breast cancer is critical for selecting the most beneficial mode of therapy for the affected patients. The estrogen receptor (ER) is a major prognostic marker, indicating the estrogen-responsive nature of breast tumors and the likelihood of response to hormonal therapy. Estrogen receptor variants may possess outlaw functions, acting in a dominant-positive (transcriptionally active in the absence of estrogen) or dominant-negative (transcriptionally inactive, while inhibiting the function of wild-type ER) manner. Developing a strong correl

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"Modulation of estrogen receptor expression and the estrogen response pathway by the pineal hormone melatonin in MCF-7 human breast cancer cells." Tulane University, 1994.

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Melatonin, the hormonal product of the pineal gland, has been shown to inhibit the development of mammary tumors in vivo and the proliferation of MCF-7 cells in vitro by mechanisms not yet identified. Previous studies have demonstrated that only human breast cancer cells which express estrogen receptor (ER) are responsive to the antimitogenic effects of melatonin, suggesting a link between the effects of melatonin and the estrogen-response pathway. MCF-7 human breast cancer cells, which are ER-positive and responsive to the mitogenic actions of estrogen, were used to examine the possible assoc

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"Localization and status of hypothalamic releasing factors in normal (DF/?) and in prolactin- and growth hormone- deficient dwarf (df/df) mice: Vasoactive intestinal peptide (VIP) and growth hormone releasing hormone (GHRH)." Tulane University, 1993.

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This study examined the stimulating factors for prolactin (PRL) and growth hormone (GH). One aim of the study was to establish an anatomical basis for a proposed releasing factor for PRL, vasoactive intestinal peptide (VIP). Ames dwarf mice, which manifest a spontaneous mutation which, when present in homozygous form (df/df), results in absence of PRL and GH, were used in the present study. Immunoreactive VIP and growth hormone releasing hormone (GHRH) were examined and compared between brains of normal and PRL and GH-deficient dwarf mice in order to see whether there is a response of VIP and

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"Adrenal corticosteroids: Central nervous system targets, mechanisms of action, and glucocorticoid regulation of preproenkephalin-gene expression." Tulane University, 1992.

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Adrenal corticosteroids have diverse effects on central nervous system (CNS) function. These include regulation of the activity of neurotransmitters-modulators, neuro- and gliogenesis, learning and behavior and neuronal and glial survival. Many of these actions are thought to be mediated at least in part, by intracellular corticosteroid receptors. A Type I receptor, which acts as a mineralocorticoid receptor in the peripheral tissues, is selective for endogenous glucocorticoids in most regions of the CNS. A Type II receptor, also known as the classical glucocorticoid receptor has a low affinit

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"Expression and regulation of Pitx genes during vertebrate organogenesis." Tulane University, 1999.

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Pitx1 and Pitx2 define a new family of bicoid related homeobox genes. The respective expression patterns of these two genes suggests their importance during vertebrate embryo development. Of particular interest is the expression and regulation of these genes during murine tooth development. The expression patterns of both Pitx1 and Pitx2 in the tooth forming region as well as the tooth defect found in patients with Rieger syndrome suggest that both Pitx1 and Pitx2 play a role in the early stages of odontogenesis. Studies show that overlapping domains of Fgf8 and Bmp4 signaling regulate the exp

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"Modulation of ROR-alpha receptor activity and the calcium/calmodulin signaling pathway by melatonin in MCF-7 human breast cancer cells." Tulane University, 2000.

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The pineal hormone, melatonin has repeatedly been shown to inhibit the proliferation of estrogen receptor alpha (ERalpha)-positive MCF-7 human breast cancer cells. Previous reports have suggested that the actions of melatonin can be mediated either through G protein-coupled membrane receptors, or via retinoid orphan receptors (RORalpha), which constitutively activate gene transcription through their corresponding response elements termed ROREs. Transient transfection assays using an RORE-luciferase reporter construct have shown that the endogenous (RORalpha), receptors expressed in MCF-7 breas

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"Proenkephalin gene expression during rat basal ganglia development and the effects of chronic morphine exposure." Tulane University, 1993.

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Proenkephalin is one of the three genes known to encode endogenous opioid peptides. An antibody directed against a unique peptide sequence within proenkephalin that is not found in any other known peptide sequence was characterized and compared to a methionine enkephalin antibody. This antibody was found to be specific for enkephalinergic cell bodies, fibers and terminals. The development of proenkephalin mRNA in the neostriatum and its derivative peptides in the globus pallidus were found to parallel neurogenetic gradients. Expression was also found early in the central nucleus of the amygdal

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Baheti, Ankur R. "Development of an anatomy identification skill set for laparoscopic and robotic minimally invasive procedures." 2008. http://proquest.umi.com/pqdweb?did=1594485631&sid=2&Fmt=2&clientId=39334&RQT=309&VName=PQD.

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Thesis (M.S.)--State University of New York at Buffalo, 2008.<br>Title from PDF title page (viewed on Jan. 14, 2009) Available through UMI ProQuest Digital Dissertations. Thesis adviser: Kesavadas, Thenkurrisi Includes bibliographical references.

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"Microanatomical characterization of Loaina uniformis: A morphologic comparison with Loa loa (Nematoda: Filarioidea)." Tulane University, 1996.

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Zoonotic filarial infections have been reported from most parts of the world. However, the range of species involved, host-parasite interactions and morphologic criteria for the specific identification of the species is still poorly known and understood. Species of Dirofilaria are the most common agents of human infection and the most studied group of zoonotic filariae. Several other groups, including species of Brugia and Onchocerca are being reported with increasing frequency. Loaina uniformis, a common parasite of rabbits in the southeastern United States, represents yet another species rec

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"Steroid regulation of LHRH in rat brain: Glucocorticoids and androgens." Tulane University, 1994.

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Luteinizing hormone releasing hormone (LHRH), a decapeptide, is synthesized in the central nervous system, released into the portal blood, and transported to the anterior pituitary, where it regulates the secretion of luteinizing hormone (LW) and follicle-stimulating hormone (FSH). Therefore, LHRH is a key integrator between the neural and endocrine systems and plays a pivotal role in promoting reproductive functions. The synthesis and secretion of LHRH are under the exquisite control of different neurotransmitters and steroid hormones, including glucocorticoids and androgens. In this disserta

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Ng, Tiong Weng. "Molecular interactions of polo-like Kinase 1 (PLK1) in colorectal cancer." Thesis, 2017. http://hdl.handle.net/1959.7/uws:46007.

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Colorectal cancer (CRC) is one of the most prevalent cancers in Australia with about a third being rectal cancer. Locally advanced rectal cancer is frequently treated with pre-operative radiotherapy (DXT) in concurrent with chemotherapy to reduce the tumour mass for better surgical access, and therefore improving the treatment outcomes. The response to DXT varies amongst individual patients, raising the need of predictive markers to prevent unnecessary toxic therapy. Polo-like kinase 1 (PLK1) is involved in cell cycling and DNA damage response (DDR) and in view of the latter, it may be a poten

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Tut, Thein Ga. "Predictive biomarkers of radiation sensitivity in rectal cancer." Thesis, 2016. http://hdl.handle.net/1959.7/uws:38000.

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Colorectal cancer (CRC) is the third most common cancer in the world. Australia, New Zealand, Canada, the United States, and parts of Europe have the highest incidence rates of CRC. China, India, South America and parts of Africa have the lowest risk of CRC. CRC is the second most common cancer in both sexes in Australia. Even though the death rates from CRC involving the colon have diminished, those arising from the rectum have revealed no improvement. The greatest obstacle in attaining a complete surgical resection of large rectal cancers is the close anatomical relation to surrounding struc

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Koloadin, Leah S. "Intraspecific and interspecific variation in the xylem functional traits of Callitris species growing along an aridity gradient." Thesis, 2020. http://hdl.handle.net/1959.7/uws:67022.

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More severe and prolonged drought events as a result of climate change, have the potential to cause broad scale forest and woodland dieback worldwide. The Australian continent is primarily comprised of arid biomes. However, rapid climate change-induced desertification threatens these surprisingly diverse ecosystems. Callitris is Australia’s most successful conifer genus, yet they remain they remain vulnerable to drought-induced decline. Given Callitris are the primary structural component of vegetation in many Arid-Australian ecosystems, their persistence is the most important factor preventin

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Fong, Sheri F. T. "The LOX and LOXL2 amine oxidases in colon and esophageal cancer." 2003. http://proquest.umi.com/pqdweb?index=0&did=765084641&SrchMode=1&sid=3&Fmt=2&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1233165331&clientId=23440.

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"Gonadal steroid regulation of NADPH-diaphorase histochemistry in the male and female rat brain." Tulane University, 1996.

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The present series of experiments examined selected brain regions to determine the effects of the gonadal steroids, estrogen and testosterone, on the reactivity of the nitric oxide synthase, NADPH-diaphorase. The results of the first experiment indicated that estrogen administration significantly increased NADPH-diaphorase reactivity 29% in the horizontal limb of the diagonal band of Broca, while testosterone administration significantly reduced NADPH-diaphorase reactivity 27% in the vertical limb of the diagonal band of Broca. The results of the second experiment indicated that 11.8% of NADPH

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"Neuronal reorganization and glial neuroimmune responses to injury in organotypic slice cultures of neonatal mouse hippocampus." Tulane University, 1996.

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The hippocampal organotypic slice culture was used to study injury in the CNS. Studies characterized factors that influenced regenerative events in the hippocampal dentate gyrus, concomitant changes in glial cell populations, and examined the role of neuroglia in repair of damaged neural tissues Deafferentation of the hippocampus causes dentate granule cell axons, known as the mossy fibers, to initiate collateral neurite sprouting. Following axonal degeneration, mossy fibers form collaterals that invade the dental molecular layer, which contains denervated granule cell dendrites (Zimmer and Ga

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"Effects of a sequential treatment regimen of melatonin and retinoic acid on MCF-7 human breast cancer cells." Tulane University, 1999.

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Neoplastic events can be marked by uncontrolled cell proliferation, and thus, one major focus of cancer research has been to identify treatments which reduce or inhibit cell growth. Over the years, various compounds, both naturally occurring and chemically synthesized, have been utilized to inhibit neoplastic cell proliferation. Two such oncostatic agents, melatonin and retinoic acid, have been shown to suppress the growth of hormone-responsive breast cancer in a similar time-course. Currently, separate clinical protocols exist for the administration of retinoids and melatonin as adjuvant ther

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Zhao, Hui Fu Yun-Xin. "A coalescent analysis for modeling the mutation process in colorectal cancer /." 2007. http://proquest.umi.com/pqdweb?did=1436357001&sid=1&Fmt=2&clientId=68716&RQT=309&VName=PQD.

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Gebremedhn, Endale G. "Exploring the incidence and variability of oxaliplatin-induced neuropathic pain symptoms in colorectal cancer patients, comparative in vivo / in vitro modelling of oxaliplatin/ 56MESS(IV) as an alternative cancer treatment, and minocycline administration as a prophylactic agent for chemotherapy-induced neuropathic pain." Thesis, 2021. http://hdl.handle.net/1959.7/uws:68146.

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Oxaliplatin is commonly used for the treatment of advanced and recurrent colorectal cancer (CRC). However, oxaliplatin-induced neuropathic pain remains a challenge for the healthcare systems worldwide. In chapter II, the incidence and impact of acute oxaliplatin-induced neuropathic pain on chemotherapy treatment in colorectal cancer patients in the first cycle from the published research literature was explored. In chapter III, the variability of oxaliplatin-induced neuropathic pain symptoms from the Southwestern Sydney Local Health District Hospitals (SWLHDHs) database of patients who receive

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