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Artykuły w czasopismach na temat "Phenotype and genotype of enterobacter aerogenes"

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Chollet, Renaud, Claude Bollet, Jacqueline Chevalier, Monique Malléa, Jean-Marie Pagès, and Anne Davin-Regli. "mar Operon Involved in Multidrug Resistance of Enterobacter aerogenes." Antimicrobial Agents and Chemotherapy 46, no. 4 (2002): 1093–97. http://dx.doi.org/10.1128/aac.46.4.1093-1097.2002.

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ABSTRACT We determined the sequence of the entire marRAB operon in Enterobacter aerogenes. It is functionally and structurally analogous to the Escherichia coli operon. The overexpression of E. aerogenes MarA induces a multidrug resistance phenotype in a susceptible strain, demonstrated by a noticeable resistance to various antibiotics, a decrease in immunodetected porins, and active efflux of norfloxacin.
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Chollet, Renaud, Jacqueline Chevalier, Claude Bollet, Jean-Marie Pages, and Anne Davin-Regli. "RamA Is an Alternate Activator of the Multidrug Resistance Cascade in Enterobacter aerogenes." Antimicrobial Agents and Chemotherapy 48, no. 7 (2004): 2518–23. http://dx.doi.org/10.1128/aac.48.7.2518-2523.2004.

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ABSTRACT Multidrug resistance (MDR) in Enterobacter aerogenes can be mediated by induction of MarA, which is triggered by certain antibiotics and phenolic compounds. In this study, we identified the gene encoding RamA, a 113-amino-acid regulatory protein belonging to the AraC-XylS transcriptional activator family, in the Enterobacter aerogenes ATCC 13048 type strain and in a clinical multiresistant isolate. Overexpression of RamA induced an MDR phenotype in drug-susceptible Escherichia coli JM109 and E. aerogenes ATCC 13048, as demonstrated by 2- to 16-fold-increased resistance to β-lactams, t
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Chevalier, Jacqueline, Jérôme Bredin, Abdallah Mahamoud, Monique Malléa, Jacques Barbe, and Jean-Marie Pagès. "Inhibitors of Antibiotic Efflux in Resistant Enterobacter aerogenes and Klebsiella pneumoniae Strains." Antimicrobial Agents and Chemotherapy 48, no. 3 (2004): 1043–46. http://dx.doi.org/10.1128/aac.48.3.1043-1046.2004.

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ABSTRACT In Enterobacter aerogenes and Klebsiella pneumoniae, efflux provides efficient extrusion of antibiotics and contributes to the multidrug resistance phenotype. One of the alkoxyquinoline derivatives studied here, 2,8-dimethyl-4-(2′-pyrrolidinoethyl)-oxyquinoline, restores noticeable drug susceptibility to resistant clinical strains. Analyses of energy-dependent chloramphenicol efflux indicate that this compound inhibits the efflux pump mechanism and improves the activity of structurally unrelated antibiotics on multidrug-resistant E. aerogenes and K. pneumoniae isolates.
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Thiolas, Aurélie, Claude Bollet, Bernard La Scola, Didier Raoult, and Jean-Marie Pagès. "Successive Emergence of Enterobacter aerogenes Strains Resistant to Imipenem and Colistin in a Patient." Antimicrobial Agents and Chemotherapy 49, no. 4 (2005): 1354–58. http://dx.doi.org/10.1128/aac.49.4.1354-1358.2005.

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ABSTRACT Enterobacter aerogenes is an agent of hospital-acquired infection that exhibits a remarkable resistance to β-lactam antibiotics during therapy. Five successive isolates of E. aerogenes infecting a patient and exhibiting a multiresistance phenotype to β-lactam antibiotics and fluoroquinolones were investigated. Among these clinical strains, four presented resistant phenotypes during successive imipenem and colistin treatments. The involved resistance mechanisms exhibited by the successive isolates were associated with alterations of the outer membrane that caused a porin decrease and l
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Charrel, R. N., J. M. Pagès, P. De Micco, and M. Mallea. "Prevalence of outer membrane porin alteration in beta-lactam-antibiotic-resistant Enterobacter aerogenes." Antimicrobial Agents and Chemotherapy 40, no. 12 (1996): 2854–58. http://dx.doi.org/10.1128/aac.40.12.2854.

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We evaluated the prevalence of impermeability as a mechanism associated with resistance against beta-lactam antibiotics in members of the family Enterobacteriaceae. During a 1-year period, 80 strains were selected from 3,110 routinely isolated strains according to their noticeable cross-resistance pattern to cephalosporins. They were tested for (i) outer membrane nonspecific porins involved in the entry of small hydrophilic molecules; (ii) the MICs of cefepime, cefotaxime, imipenem, and moxalactam; and (iii) beta-lactamase production. Immunological investigations using specific probes showed t
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Al-Doori, Zainab. "Heterospecific transcription of theEscherichia coli rpoB-3 allele in Gram-negative bacteria." Genetical Research 50, no. 2 (1987): 87–90. http://dx.doi.org/10.1017/s0016672300023478.

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SummaryrpoB is the structural gene for the β-subunit ofE. coliRNA polymerase. TherpoB-3 allele confers resistance to the antibiotic rifampicin and is unusual in being dominant to the wild-type allele. We used the plasmid pZD23, a derivative of the broad host range conjugative plasmid RP4, to introduce therpoB-3 allele into a range of bacterial species. Species belonging to the same family asE. coli(Enterobacter aerogenes, Citrobacter freundii, Hafnia alvei møller, Klebsiella pneumoniae, Salmonella typhimurium) expressedrpoB-3 to give a rifampicin resistant phenotype; this demonstrated heterosp
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Gayet, Stéphane, Renaud Chollet, Gérard Molle, Jean-Marie Pagès, and Jacqueline Chevalier. "Modification of Outer Membrane Protein Profile and Evidence Suggesting an Active Drug Pump in Enterobacter aerogenes Clinical Strains." Antimicrobial Agents and Chemotherapy 47, no. 5 (2003): 1555–59. http://dx.doi.org/10.1128/aac.47.5.1555-1559.2003.

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ABSTRACT Two clinical strains of Enterobacter aerogenes that exhibited phenotypes of multiresistance to β-lactam antibiotics, fluoroquinolones, chloramphenicol, tetracycline, and kanamycin were investigated. Both strains showed a porin pattern different from that of a susceptible strain, with a drastic reduction in the amount of the major porin but with an apparently conserved normal structure (size and immunogenicity), together with overproduction of two known outer membrane proteins, OmpX and LamB. In addition, the full-length O-polysaccharide phenotype was replaced by a semirough Ra phenoty
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Bonnet, R., J. L. M. Sampaio, R. Labia та ін. "A Novel CTX-M β-Lactamase (CTX-M-8) in Cefotaxime-ResistantEnterobacteriaceae Isolated in Brazil". Antimicrobial Agents and Chemotherapy 44, № 7 (2000): 1936–42. http://dx.doi.org/10.1128/aac.44.7.1936-1942.2000.

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ABSTRACT To estimate the diversity of extended-spectrum β-lactamases in Brazil, 18 strains from different species of the familyEnterobacteriaceae exhibiting a positive double-disk synergy test were collected by a clinical laboratory from several hospitals in Rio de Janeiro, Brazil, in 1996 and 1997. Four strains (Proteus mirabilis, Enterobacter cloacae,Enterobacter aerogenes, and Citrobacter amalonaticus) hybridized with a 550-bp CTX-M probe. The P. mirabilis strain produced a CTX-M-2 enzyme. The E. cloacae, E. aerogenes, and C. amalonaticus isolates harbored a bla gene which was identified by
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Yousuf, Farzana, Ruqaiyyah Siddiqui, and Naveed Khan. "Acanthamoeba castellanii of the T4 genotype is a potential environmental host for Enterobacter aerogenes and Aeromonas hydrophila." Parasites & Vectors 6, no. 1 (2013): 169. http://dx.doi.org/10.1186/1756-3305-6-169.

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Tzelepi, Eva, Panagiota Giakkoupi, Danai Sofianou, Veneta Loukova, Anastassia Kemeroglou та Athanassios Tsakris. "Detection of Extended-Spectrum β-Lactamases in Clinical Isolates of Enterobacter cloacae andEnterobacter aerogenes". Journal of Clinical Microbiology 38, № 2 (2000): 542–46. http://dx.doi.org/10.1128/jcm.38.2.542-546.2000.

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The aim of the present study was to investigate the frequency of extended-spectrum β-lactamases (ESBLs) in a consecutive collection of clinical isolates of Enterobacter spp. The abilities of various screening methods to detect ESBLs in enterobacters were simultaneously tested. Among the 68 consecutive isolates (56Enterobacter cloacae and 12 Enterobacter aerogenes isolates) that were analyzed for β-lactamase content, 21 (25 and 58%, respectively) possessed transferable ESBLs with pIs of 8.2 and phenotypic characteristics of SHV-type enzymes, 8 (14.3%) of the E. cloacae isolates produced a previ
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