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Artykuły w czasopismach na temat „Phenylephrine and Mephentermine”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

S, Sonika, Shalini Y, Nebu CA, Manjunath HG, and Priya L. "Comparison of intravenous bolus phenylephrine, ephedrine and mephentermine for maintenance of arterial blood pressure during spinal anaesthesia in caesarean section." Journal of Medical and Scientific Research 12, no. 3 (2024): 235–40. http://dx.doi.org/10.17727/jmsr.2024/12-44.

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Background: Subarachnoid block, although being highly efficient, often has limitation such as hypotension which can result in adverse maternal and fetal outcome, continues to be a matter of concern to the Anesthesiologist. The study was to compare the effect of phenylephrine, ephedrine and mephentermine, for maintenance of arterial pressure during spinal anaesthesia for caesarean section. Methodology: A prospective randomized double blinded study involving 90 patients with hypotension after subarachnoid block under spinal anesthesia was conducted, dividing them into three groups: P (Phenylephr

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A, Garg, Rehman S, Bhatia R, and Pathania J. "Comparison of phenylephrine and mephentermine for preventing oxytocin-induced hemodynamic changes during spinal anaesthesia." Journal of Medical and Scientific Research 13, no. 2 (2025): 113–19. https://doi.org/10.17727/jmsr.2024/13-20.

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Background: Spinal anaesthesia is a safe and reliable regional technique for the caesarean section, offering rapid onset, effective analgesia and reduced aspiration risk compared to general anaesthesia. This study aimed to compare phenylephrine and mephentermine in preventing oxytocin-induced hemodynamic changes during the caesarean section under spinal anaesthesia. Materials and methods: The study included 64 patients aged 18 to 40 years with American Society of Anesthesiologists (ASA) II physical status who were scheduled for elective lower segment caesarean section (LSCS) under spinal anaes

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Senapati, Laxman K. "Comparison of infusions of phenylephrine, norepinephrine, and mephentermine on maternal hemodynamics and neonatal outcomes in caesarean section under spinal anaesthesia." Journal of Medical pharmaceutical and allied sciences 13, no. 1 (2024): 6392–400. http://dx.doi.org/10.55522/jmpas.v13i1.5919.

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Although the subarachnoid block is the preferred anesthetic technique for the caesarean section, on the downside it is often associated with complications like maternal hypotension. We compared phenylephrine, norepinephrine, and mephentermine infusions to maintain blood pressure during the caesarian section under subarachnoid block. Our study included 240 parturients with singleton-term pregnancies undergoing a caesarian section under spinal anesthesia. Following spinal anesthesia till the delivery of the baby, parturients randomly assigned to three groups received phenylephrine, norepinephrin

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Ekramuddin, Dr, Dr Satyam, Dr Ashutosh Jha, and Dr Sabir Hasnat. "Comparison Of Bolus Ephedrine, Mephentermine And Phenylephrine For The Management Of Hypotension During Spinal Anaesthesia For Caesarean Section – A Clinical Study." IOSR Journal of Dental and Medical Sciences 23, no. 11 (2024): 61–68. https://doi.org/10.9790/0853-2311086168.

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Background: Anaesthesia to a parturient is not only unique but also requires highest degree of care because the anaesthesiologist has to look after two individuals, the mother and fœtus. Hypotension during spinal anaesthesia for caesarean delivery can have detrimental effects on both mother and neonate. These effects include decreased utero-placental blood flow, impaired foetal oxygenation with asphyxial stress and foetal acidosis and maternal symptoms of low cardiacoutput such as nausea, vomiting, dizziness and decreased consciousness. Vasopressor like Ephedrine, Mephentermine, Phenylephrine,

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Narendra, Thadu, Kumar Suggala Kiran, and Anusha T. "Comparative Efficacy of Phenylephrine and Mephentermine in Mitigating Hemodynamic Responses to Oxytocin Administration during Elective Cesarean Section." International Journal of Pharmaceutical and Clinical Research 16, no. 12 (2024): 1711–15. https://doi.org/10.5281/zenodo.14636804.

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<strong>Introduction:</strong> Cesarean sections performed under spinal anaesthesia are associated with maternal hypotension, exacerbated by oxytocin administration during surgery. Effective management of these hemodynamic changes is crucial for maternal and fetal safety. Phenylephrine, a selective α1-adrenergic agonist, and mephentermine, a mixed-action sympathomimetic, are commonly used vasopressors. However, comparative data on their efficacy in mitigating oxytocin-induced hemodynamic responses during cesarean sections is limited. <strong>Materials and Methods:</strong>&nbsp

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Annet, Thatal, Narwat Yogesh, and Arora Gunjan. "Comparison of Ephedrine, Mephentermine and Phenylephrine for the Management of Hypotension during Spinal Anesthesia for Caeserian Section." International Journal of Pharmaceutical and Clinical Research 14, no. 11 (2022): 708–14. https://doi.org/10.5281/zenodo.13874044.

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<strong>Introduction:</strong> Numerous pressor agents have been tried to counteract the hypotensive effect of subarachnoid block, usually by vasoconstriction and also by increasing the cardiac output.  In practice, the most commonly used drugs are the sympathomimetic agents which exert their effects through the adrenergic receptors, either acting directly or indirectly by inducing the release of noradrenaline which further acts on these receptors. Aim and objectives: To compare the efficacy of IV bolus phenylephrine, ephedrine and mephentermine for the maintenance of hemodynamic sta

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D.V., Ravi Kumar, Sahoo Suryasnata, Pattnaik Anija, Behera Udaynath, and Goud Parimita. "Comparison of Bolus Ephedrine, Mephentermine and Phenylephrine for the Management of Hypotension during Spinal Anaesthesia for Caesarean Section: A Clinical Study." International Journal of Pharmaceutical and Clinical Research 15, no. 1 (2023): 190–200. https://doi.org/10.5281/zenodo.13131874.

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<strong>Background: </strong>In this study, we wanted to compare the efficacy of ephedrine, mephentermine and phenylephrine in treating the hypotension for caesarean section and their undesirable side effects. <strong>Methods: </strong>This was a hospital based prospective double blind randomized manner study conducted among 90 patients who underwent elective and emergency lower segment caesarean section (LSCS) in the Department of Obstetrics, S.C.B. Medical College& Hospital, Cuttack from June 2021 to July 2022, after obtaining clearance from Institutional Ethics Committee

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Mohta, M., S. S. Janani, A. K. Sethi, D. Agarwal, and A. Tyagi. "Comparison of Phenylephrine Hydrochloride and Mephentermine Sulphate for Prevention of Postspinal Hypotension." Obstetric Anesthesia Digest 31, no. 4 (2011): 228–29. http://dx.doi.org/10.1097/01.aoa.0000406682.55400.8f.

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Mohta, M., S. Sai Janani, A. K. Sethi, D. Agarwal, and A. Tyagi. "Comparison of phenylephrine hydrochloride and mephentermine sulphate for prevention of post spinal hypotension." Anaesthesia 65, no. 12 (2010): 1200–1205. http://dx.doi.org/10.1111/j.1365-2044.2010.06559.x.

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Naresh Satia, Shweta, Sameer Kulkarni, and Jyoti Kale. "Comparison of Phenylephrine, Ephedrine and Mephentermine for Control of Hypotension following Spinal Anaesthesia for Infra-Umbilical Surgeries." International Journal of Science and Research (IJSR) 10, no. 7 (2021): 47–52. https://doi.org/10.21275/sr21625153917.

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Tadooru, Tejaswini. "Comparison of Bolus Phenylephrine, Ephedrine and Mephentermine for the Management of Hypotension during Spinal Anaesthesia in Caesarean Section: A Clinical Study." Indian Journal of Anesthesia and Analgesia 7, no. 1(Part-2) (2020): 361–67. http://dx.doi.org/10.21088/ijaa.2349.8471.7120.49.

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Chandak, Aruna V., Deepjit Bhuyan, Amol P. Singam, and Bhakti Patil. "Comparison of bolus phenylephrine, Ephedrine and Mephentermine for maintenance of arterial pressure during Spinal anaesthesia in Caesarean section." RESEARCH JOURNAL OF PHARMACY AND TECHNOLOGY 14, no. 3 (2021): 1349–52. http://dx.doi.org/10.5958/0974-360x.2021.00240.7.

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Kumar, Dr P. Savanth, Dr P. Lokesh, and Dr Balad Karunakar. "A comparative study of bolus phenylephrine and mephentermine for treatment of hypotension during spinal anaesthesia for caesarean section." International Journal of Medical Anesthesiology 3, no. 4 (2020): 93–99. http://dx.doi.org/10.33545/26643766.2020.v3.i4b.171.

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Deepali, Rahate Gomase. "A Comparative Study on the Use of Prophylactic Intravenous Ephedrine to Reduce Hypotension During Spinal Anaesthesia for Caesarean Sections." International Journal of Toxicological and Pharmacological Research 12, no. 12 (2022): 263–69. https://doi.org/10.5281/zenodo.7948304.

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<strong>Background: </strong>The most frequently used and favoured method for caesarean birth is spinal anaesthesia. It is however linked to hypotension, which is harmful to the mother and foetus. The goal of the study is to ascertain how bolus intravenous ephedrine can reduce spinal-induced hypotension. Due to decreased uteroplacental blood flow, regional anaesthetic for Caesarean delivery is linked to a high prevalence of maternal hypotension and may cause foetal acidemia. Preloading with fluids, avoiding aortocaval compression, and giving vasopressor medications are all common ways to preve

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M, Srinivasa Rao, Satyanarayana Satyanarayana, Ramesh Ramesh, and Saisuraj Saisuraj. "COMPARISON OF INTRAVENOUS BOLUS PHENYLEPHRINE, EPHEDRINE AND MEPHENTERMINE FOR MAINTENANCE OF ARTERIAL PRESSURE DURING SPINAL ANAESTHESIA IN CAESAREAN SECTION." Journal of Evolution of Medical and Dental Sciences 7, no. 15 (2018): 1905–11. http://dx.doi.org/10.14260/jemds/2018/429.

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Lonkar, Dr Sarika Sudhir, Dr Sonal Sagar Khatavkar, Dr W. S. Thatte, and Dr Naramaneni Santhi. "Comparison Between Phenylephrine, Ephedrine And Mephentermine In Preventing Hypotension During Spinal Anesthesia For Caesarean Section And Their Effect On Fetal Outcome." IOSR Journal of Dental and Medical Sciences 15, no. 09 (2016): 52–58. http://dx.doi.org/10.9790/0853-1509135258.

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Mukhopadhyay, Bhabananda, and Manas Ranjan Panigrahi. "Efficacy and safety of intravenous phenylephrine and mephentermine for management of hypotension during spinal anaesthesia: A single blind prospective and comparative study among patients undergoing cesarean section." Indian Journal of Clinical Anaesthesia 7, no. 1 (2020): 177–81. http://dx.doi.org/10.18231/j.ijca.2020.031.

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Sinha, Garima, Hemalatha S, and Gurudatt C L. "Effectiveness of intravenous boluses of phenylephrine, ephedrine and mephentermine as vasopressors for management of perioperative hypotension in elective lower segment caesarean section under spinal anaesthesia – A prospective comparative study." Indian Journal of Clinical Anaesthesia 7, no. 1 (2020): 46–53. http://dx.doi.org/10.18231/j.ijca.2020.009.

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Bhattarai, B., S. Y. Bhat, and M. Upadya. "Comparison of Bolus Phenylephrine, Ephedrine and Mephentermine for Maintenance of Arterial Pressure during Spinal Anesth." Journal of Nepal Medical Association 49, no. 177 (2010). http://dx.doi.org/10.31729/jnma.128.

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INTRODUCTION: Hypotension is common following spinal anesthesia. Various vasopressors have been indicated to prevent it. The study compares three such agents namely phenylephrine, ephedrine and mephentermine. METHODS: The study included 90 patients undergoing elective and emergency cesarean section who developed hypotension following subarachnoid blockade. Parturient were randomly divided into three groups each group had 30 patients. Group P received bolus of Phenylephrine 25 microgram, where as group E received Ephedrine 5mg and Group M received Mephentermine 6mg. RESU

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Tomar, Jahnavi, Kashish Khan, and Debapriya Sarkar. "A COMPARATIVE STUDY OF MEPHENTERMINE AND PHENYLEPHRINE IN THE TREATMENT OF HYPOTENSION DURING SPINAL ANAESTHESIA FOR CAESAREAN SECTION." GLOBAL JOURNAL FOR RESEARCH ANALYSIS, May 15, 2023, 25–27. http://dx.doi.org/10.36106/gjra/2000904.

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Purpose: To compare the effects of mephentermine and phenylephrine in maintaining arterial blood pressure in patients undergoing caesarean section under spinal anaesthesia who develop hypotension. Materials and method- This randomized study consisted of 42 parturient women who underwent elective caesarean section under spinal anaesthesia and developed hypotension during the operation. The patients were equally divided into 2 groups: Group I & Group II. Participants in Group I received intravenous bolus of Phenylephrine 100 mcg whereas participants in Group II received intravenous bolus of

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Singha, Suman, and Lalita Jeenger. "A COMPARATIVE STUDY OF PHENYLEPHRINE, MEPHENTERMINE AND NOREPINEPHRINE IN THE TREATMENT OF HYPOTENSION DURING SPINAL ANAESTHESIA FOR CAESAREAN SECTION." GLOBAL JOURNAL FOR RESEARCH ANALYSIS, November 15, 2024, 116–19. https://doi.org/10.36106/gjra/9707212.

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Background: Post-spinal hypotension is a common complication during caesarean sections under spinal anaesthesia, necessitating effective management protocols. Previous studies have explored various vasopressors, such as norepinephrine, phenylephrine, and mephentermine, to control this condition, but comparative effectiveness and safety remain under investigation. Objective: This study aims to compare the efcacy and safety of mephentermine, phenylephrine, and norepinephrine in managing hypotension during spinal anesthesia for caesarean sections. Method: A total of 114 patients undergoing elect

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Ramesh, R., D. Balagi, and VP Dayananda. "To Compare the Efficacy of Phenylephrine and Mephentermine in Maintaining Arterial Pressure During Spinal Anaesthesia in Infra Umbilical Surgeries." September 6, 2016. https://doi.org/10.19070/2332-2780-1600068.

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Introduction: It is important to find an effective method to prevent and treat hypotension during subarachnoid block. Hence we compare the bolus doses of Phenylephrine and Mephentermine to treat hypotension post subarachnoid block. Methods: This randomized study was conducted in 100 patients of ASA I or II physical status undergoing infraumbilical surgeries under subarachnoid block. Patients were randomized into 2 groups of 50 each. Group P-Phenylephrine of 0.1 mg I.V bolus and Group M-Mephenteramine 6mg I.V bolus given when patient develops hypotension >20% basal respectively. Both the gro

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Divyabharathi, Srinivasan, Sinam Neetu Devi, Jonan Puni Kay, et al. "Mephentermine vs. Phenylephrine for Prevention and Management of Maternal Hypotension during Caesarean Section under Spinal Anaesthesia and their Effects on Foetal Outcome- A Randomised Control Trial." JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2022. http://dx.doi.org/10.7860/jcdr/2022/55818.16708.

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Introduction: For the best maternal and foetal outcome during caesarean section under spinal anaesthesia, maintaining Systolic Blood Pressure (SBP) at 100% of the baseline is necessary. Mephentermine and Phenylephrine are both sympathomimetic drugs used for timely correction of maternal hypotension. Aim: To compare the effect of intravenous bolus administration of mephentermine and phenylephrine for prevention and management of maternal hypotension and to evaluate the foetal outcome. Materials and Methods: In this randomised double-blinded controlled trial, a total of 150 American Society of A

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Ranika Manhas, Khushboo Jain, Prerna Attal, Jyoti Priya, and Neel Pankaj. "A Comparative Study of the Efficacy of Intravenous Bolus of Mephentermine and Phenylephrine in Maintaining Arterial Blood Pressure During Spinal Anaesthesia in Caesarean Section." Journal of Evolution of Medical and Dental Sciences, August 12, 2022, 770–74. http://dx.doi.org/10.14260/jemds.v11i9.194.

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BACKGROUND Spinal anaesthesia is the most popular and elegant approach for obstetric patients undergoing caesarean section due to its several advantages. Hypotension resulting from sympathectomy due to subarachnoid block can have detrimental effects on the foetus as well as the mother, so needs to be prevented and treated adequately. Vasopressors for the treatment of hypotension have a well-established role as vasodilatation is the primary cause of the reduction in arterial blood pressure. The primary objective of the study was to compare mephentermine and phenylephrine with respect to t

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-, Sujith Panasseril Jayapradeep. "Comparison of bolus ephedrine,mephentermine and phenylephrine for maintenance of arterial pressure during caesarian section, a double blind study." International Journal on Science and Technology 16, no. 2 (2025). https://doi.org/10.71097/ijsat.v16.i2.4254.

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Hypotension has been observed in more than 80 % of caesarian sections done under spinal anesthesia. Crystalloids, colloids and positioning of the patient are used to circumvent the fall in BP. But for a quicker response, vasopressors has to be used. We aim to study the effect of giving standard bolus doses of the most commonly used vasopressors viz mephentermine, ephedrine and phenylephrine to prevent the initial hypotension after spinal anesthesia in patients undergoing elective and emergency caesarian sections

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"Comparison of Phenylephrine, Ephedrine, and Mephentermine for Control of Hypotension After Spinal Anesthesia in Subumbilical Surgery." Journal of Contemporary Medical Practice 4, no. 1 (2022). http://dx.doi.org/10.53469/jcmp.2022.04(01).18.

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"Comparison of single dose phenylephrine, ephedrine and mephentermine for maintenance of arterial pressure during spinal anesthesia in caesarean section." Journal of Medical Science And clinical Research 11, no. 02 (2023). http://dx.doi.org/10.18535/jmscr/v11i2.08.

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"A Comparative Study of Bolus Phenylephrine and Mephentermine for Treatment of Hypotension during Spinal Anesthesia for Cesarean Section." Internet Journal of Anesthesiology 19, no. 2 (2009). http://dx.doi.org/10.5580/1ab6.

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R, Ramesh, Balagi D, and Dayananda VP. "To Compare the Efficacy of Phenylephrine and Mephentermine in Maintaining Arterial Pressure During Spinal Anaesthesia in Infra Umbilical Surgeries." International Journal of Anesthesiology & Research, September 6, 2016, 331–35. http://dx.doi.org/10.19070/2332-2780-1600068.

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"Vasopressors for managing maternal hypotension during cesarean section under spinal anesthesia: A systematic review and network meta-analysis." Signa Vitae, 2020. http://dx.doi.org/10.22514/sv.2020.16.0094.

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Introduction: Spinal anesthesia during elective cesarean section often induces maternal hypotension, and vasopressors are the most reliable agents to counteract this. We conducted a systematic review and network meta-analysis to compare and specifically evaluate the efficacy of vasopressors in preventing maternal hypotension (effectiveness) and decreasing fetal acidosis (safety) in parturients undergoing spinal anesthesia for cesarean section. Methods: We performed a systematic and comprehensive search to identify all randomized controlled studies on vasopressors to manage maternal hypotension

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