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Rozprawy doktorskie na temat „PhoD”

Autor: Grafiati
Data publikacji: 2 czerwca 2025
Data aktualizacji: 31 lipca 2025

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1

Klein, Marco Jan [Verfasser], and A. S. [Akademischer Betreuer] Ulrich. "Membraninteraktionen der Tat-abhängigen Translokase von PhoD aus B. subtilis / Marco Jan Klein. Betreuer: A. S. Ulrich." Karlsruhe : KIT-Bibliothek, 2012. http://d-nb.info/1022123939/34.

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2

Vasconcelos, Fernanda Nogales da Costa. "Caracterização dos genes phoA1, phoA2, phoB, phoU e PstS, membros do regulon PHO de Chromobacterium violaceum." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-24092014-161707/.

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Chromobacterium violaceum é uma bactéria de vida livre, móvel, que habita fontes de água e solos pobres de regiões tropicais e subtropicais. Nestes habitats, em que a concentração de fosfato é baixa, o regulon PHO encontra-se ativado. No laboratório, esta bactéria é capaz de crescer razoavelmente bem, apesar da limitação de fosfato, atingindo um rendimento celular similar ao observado na abundância deste nutriente. Mutações nos genes pstS, phoU, phoA1 e phoA2 foram construídas. As mutações pstS e phoU não causaram qualquer alteração no padrão de expressão da fosfatase alcalina, sugerindo que e
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3

Loney, Erica. "PhoR, PhoP and MshC: Three essential proteins of Mycobacterium tuberculosis." University of Toledo / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1396606314.

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4

Le, Sage Valerie. "Ligand sensing and signal trasnduction by the two-component system PhoP/PhoQ." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=95624.

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The Citrobacter rodentium genome sequence contains a phoPQ operonhomologous (~79% identity) to that of S. typhimurium. We report that C. rodentiumPhoQ senses fluctuations in Mg2+ concentrations and acidic pH. Surprisingly, PhoQwas not activated by the presence of AMPs. However, activation by AMPs is observedwhen C. rodentium PhoP/PhoQ was expressed in as. typhimurium background. Weidentified an outer membrane protease of the omptin family that was responsible forinhibiting PhoQ activation by AMPs. In stark contrast to S. typhimurium, which relieson LPS modifications to resist AMPs, our results
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5

Salazar, Michael E. Jr (Michael Edward). "Induction kinetics of the PhoQ-PhoP two-component system in Escherichia coli." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/104179.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2016.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Cells rely on signal transduction systems to sense and respond to changes in their enviroments. When a stimulus is present, the corresponding signal transduction system will activate and enact the appropriate biological response, often by modulating target gene expression. In many cases, the temporal dynamics of the activation of target gene expression in the presence of constant stimulus is complex, and often exhibits one or se
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6

Politis, Panagiotis K. "The role of chromatin in the regulation of PHO5 and PHO3 genes in Saccharomyces cerevisiae." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343632.

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7

Münsterkötter, Martin. "Kooperative Wechselwirkungen von Transkriptionsfaktoren und Histonen mit Promotorelementen der Phosphatasegene PHO5 und PHO8 in Saccharomyces cerevisiae." Diss., lmu, 2001. http://nbn-resolving.de/urn:nbn:de:bvb:19-853.

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8

Gellatly, Shaan Lae. "Regulation of the PhoP-PhoQ two-component system in Pseudomonas aeruginosa and its role in virulence." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/42991.

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Pseudomonas aeruginosa is an opportunistic bacterial pathogen that can cause severe infections in individuals with underlying medical conditions. P. aeruginosa primarily infects at epithelial surfaces where it interacts initially via type IV pili, flagella and LPS. Two component regulatory systems control many aspects of pseudomonal physiology and mediate adaptation to environmental changes including those that occur in the host. This thesis outlines the contributions of these systems to the cytotoxicity to epithelial cells and sheds light on the regulation mediated by the two-component sensor
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9

Rodrigues, Alves Lucas Bocchini. "Patogenicidade de Salmonella Gallinarum com deleção dos genes phoP e phoQ (SG∆phoPQ) em aves comerciais." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/152283.

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Submitted by Lucas Bocchini Rodrigues Alves null (lucasbocchini@gmail.com) on 2017-12-05T19:45:59Z No. of bitstreams: 1 Dissertação_Lucas_Bocchini_Rodrigues_Alves.pdf: 48834271 bytes, checksum: 5031c0180284664e9a7c99d9701586b4 (MD5)<br>Submitted by Lucas Bocchini Rodrigues Alves null (lucasbocchini@gmail.com) on 2017-12-11T18:47:10Z No. of bitstreams: 1 Dissertação_Lucas_Bocchini_Rodrigues_Alves.pdf: 48834271 bytes, checksum: 5031c0180284664e9a7c99d9701586b4 (MD5)<br>Approved for entry into archive by Karina Gimenes Fernandes null (karinagi@fcav.unesp.br) on 2017-12-13T11:36:05Z (GMT) No.
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10

Reinke, Hans. "Die Rolle des SAGA-Komplexes bei Aktivatorbindung und Chromatinöffnung am PHO5- und PHO8-Promotor in Saccharomyces cerevisiae." Diss., lmu, 2004. http://nbn-resolving.de/urn:nbn:de:bvb:19-19064.

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11

Hertel, Christina. "In Vitro Studies of Nucleosome Positioning and Stability at the PHO5 and PHO8 Promoters in Saccharomyces cerevisiae." Diss., lmu, 2006. http://nbn-resolving.de/urn:nbn:de:bvb:19-59424.

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12

Orgul, Sibel. "Ph.d." Thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/663526/index.pdf.

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This study was carried out with Beypazari trona ore having a grade about 85 % trona (Na2CO3.NaHCO3.2H2O). The main target of the study is the determination of calcinations and leaching parameters, which are the two main unit operations in the production of soda ash (Na2CO3) from trona ore. Calcination parameters<br>calcination duration, calcination temperature and particle size were determined by using three different heat treatment systems, namely laboratory type muffle furnace, up draught furnace and microwave oven. As an alternative, wet type microwave-induced calcination which completes th
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13

Coornaert, Audrey. "Etude de la régulation post-transcriptionnelle de l'expression du système à deux composants PhoQ-PhoP par les ARN régulateurs chez Escherichia coli." Paris 7, 2012. http://www.theses.fr/2012PA077129.

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Les bactéries ont développé diverses stratégies leur permettant de survivre aux brusques changements de leur environnement. Par exemple, les systèmes à deux composants (SDC) sont des régulateurs transcriptionnels majeurs: souvent, une kinase, stimulée dans des conditions spécifiques, active le régulateur transcriptionnel qui lui est associé, afin de permettre la régulation de l'expression de ses gènes cibles. PhoQ-PhoP est un SDC central, activé dans des conditions de faible concentration de magnésium, d'acidification du milieu ou encore par les peptides antimicrobiens. En réponse, il active l
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14

Johansson, Erik. "Phos Graphis." Thesis, Blekinge Tekniska Högskola, Sektionen för teknokultur, humaniora och samhällsbyggnad, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-1627.

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Phos Graphis är en mötesplats för fotografer och modeller. Denna mötesplats ska fungera som en grund för att hitta den medpart man söker, t.ex. en fotograf som letar efter en modell till ett projekt. Användarna erbjuds även egna gallerier och möjligheter att diskutera i forum samt privat meddelandefunktionalitet. Grundtanken är att Phos Graphis ska fungera som ett verktyg för att lättare kunna utvecklas inom sin roll.
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15

Ghorbel, Sofiane. "Caractérisation et régulation de l'expression de l'opéron phoR/phoP et du gène ppk qui jouent un rôle dans le contrôle de la biosynthèse d'antibiotiques chez Streptomyces lividans." Paris 11, 2004. http://www.theses.fr/2004PA112056.

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J'ai étudié au cours de ma thèse les relations existant entre le métabolisme du phosphate et la production d'antibiotiques chez Streptomyces lividans. J'ai plus particulièrement cherché à élucider la dynamique de régulation du gène ppk et du système à deux composants phoR/phoP. On a observé qu' in vivo, Ppk joue un rôle crucial dans la régénération de l'ATP à partir de l'ADP et des polyphosphates. L'expression de ppk est induite en condition de limitation en phosphate d'une manière dépendante de PhoR/PhoP et réprimée en condition d'excès de phosphate et d'ATP par un répresseur putatif. Le phén
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16

Hussaini, Muzhgan. "Luminous Land of Phon." Thesis, Virginia Tech, 2019. http://hdl.handle.net/10919/91402.

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This thesis, Luminous Land of Phon, explores how architectural spaces, even interior spaces, interact with nature along different dimensions. Light and sound are the two very powerful elements of nature and are the focus of this study. Louis Kahn once said: "The sun does not realize how wonderful it is until after a room is made." (Source: https://www.quotetab.com/quotes/by-louis-kahn#GdaYdAIrZ8tmvcyh.97) The question of nature is explored in an urban environment to challenge the tired dualistic division between the human and the natural world. This project
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17

Gardner, Stewart G. "Studies of PhoU in Escherichia coli: Metal Binding, Dimerization,Protein/Protein Interactions, and a Signaling Complex Model." BYU ScholarsArchive, 2014. https://scholarsarchive.byu.edu/etd/5685.

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Phosphate is an essential nutrient for all forms of life. Escherichia coli has a PhoR/PhoB two component regulatory system that controls the expression of various genes whose products allow the cell to thrive in low phosphate environments. The signaling mechanism of the PhoR/PhoB system has been studied and the phosphorylation cascade that controls gene expression is well understood. What is still unknown is how PhoR senses the phosphate level of the environment. The PstS, PstC, PstA, PstB, and PhoU proteins play a role in this signal sensing. This work confirms the hypothesis that the PstSCAB
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18

Lorraine, Ross James. "PhD - Composition." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398867.

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19

Boardman, Gregory. "Musical composition : PhD." Thesis, Keele University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269183.

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20

Fretwell, Paul. "PhD in composition." Thesis, City University London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270604.

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21

Riddell, Richard Rodford. "PhD by publication." Thesis, Bath Spa University, 2012. http://researchspace.bathspa.ac.uk/1578/.

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This submission provides a commentary on thirteen of Richard Riddell's publications between 1999 and 2010. It explains the professional and policy contexts from the early 1990s onwards, when the author was a senior Local Authority officer, which gave rise to the thinking behind the first phase of his publications. These included the development of a bespoke school improvement process, deeply rooted in the context of the communities served by a school, and involving the development of an urban pedagogy and curricula. The centre piece of this phase was Schools for Our Cities (Riddell, 2003b). At
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22

Bednall, David Neil. "PhD in Composition." Thesis, University of Bristol, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.684646.

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The theme of the works in this portfolio is the creation of an original and distinctive personal language through the use of traditional methods of composition and means of performance. The works have therefore had to rely on their musical argument alone. There is a common strand running through the three works, which is the use of the organ as an essential part of the ensemble. This instrument is used in a variety of guises across the works, including as a largely accompanimental force, as part of an ensemble, and as a 'sound source'. The works show a variety of approaches to structure, inclu
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23

Kalodikis, Georgia. "PhD in composition." Thesis, Goldsmiths College (University of London), 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539853.

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24

Diers, Donna. "Between practice and ... ... : Ph.D by publication /." Electronic version, 2002. http://adt.lib.uts.edu.au/public/adt-NTSM20040903.145833/index.html.

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25

Wu, Jesse 1972. "Towards a poly-phon-ic environment." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/70865.

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Thesis (M. Arch.)--Massachusetts Institute of Technology, Dept. of Architecture, 1998.<br>Includes bibliographical references (p. 96-99).<br>This thesis explores an architectural/landscape environment where polyphonic metaphors are the means for exploration and investigation. Polyphonic, as described in musical definitions/ terms, is the style of composition in which two or more distinctly independent but organically related parts sound against one another. This combination produces associations within the piece that relate to various time lengths and musical instruments when particular musica
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26

Singh, Daniel. "From ABC to PhD." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-163039.

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27

Warner, Timothy John. "PHD by Published Works." Thesis, University of Salford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490444.

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The thesis explores the complex relationship between modern audio technologies and the art of popular music through close scrutiny specific artefacts, a largely neglected area of musicological research. The detailed analyses presented here reveal the ways in which particular analogue and digital audio technologies are used, and how these have tended to shape and inform the musical and sonic characteristics of popular music recordings and related artefacts.
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28

Knight, Stephen. "PhD in original composition." Thesis, University of Wolverhampton, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425751.

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Sammoutis, Evis. "PhD in music composition." Thesis, University of York, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428424.

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30

Smart-Smith, Pamela Cristina. "Trauma and the PhD." Diss., Virginia Tech, 2021. http://hdl.handle.net/10919/103887.

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In writing this autoethnography, I invite you to enter into my world. It is not a world that is easy, or altogether happy. In the end, though, it is a story of survival and of perseverance. Trauma touches almost every person in some way. War, sexual abuse, physical and emotional abuse, death, and difficult life events color how we make sense of the world. Trauma may happen in one blinding moment or slowly eat away at us for years. Writing is often a way to cope with that trauma. This dissertation represents a small portion of my traumatic lived experiences that led me up to the doctoral proces
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31

Caine, Edward. "PhD portfolio of compositions." Thesis, University of York, 2013. http://etheses.whiterose.ac.uk/4782/.

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My portfolio of compositions comprises 13 original composition scores and accompanying CD and DVD media. This work spans a six year period from 2006- 2012 and is written for a variety of instruments from solo piano and vocal works through to large scale orchestral and choral. Nearly all the works have been commissioned and performed professionally and recordings of the performances are included. There are several arcs to the development of my composition that are displayed in this portfolio, and the commentary splits these into four main categories: mechanics of performance, exploring vocal te
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32

Mcandrew, Peter Craig. "Characterisation of the Pho4 transcription activation domain." Thesis, Institute of Cancer Research (University Of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314104.

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33

Krogh, Hansen Helle. "Ældreomsorg i et pædagogisk perspektiv : Ph.D.-afhandling /." Roskilde : Forskerskolen i livslang læring, Institut for uddannelsesforskning, Roskilde universitetscenter, 2005. http://hdl.handle.net/1800/2082.

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34

Bruun, Hansen Karsten. "Miljøproblematikken i et identitets- og læringsperspektiv : ph.d.-afhandling /." Hørsholm : By og Byg, Statens Byggeforskningsinstitut, 2002. http://www.sbi.dk/udgivelser/publikationer/uden%5Ffor%5Fserie/phd%5Fmiljoeproblemer/kbh%5Fphd.pdf.

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Ph.d.-afhandling, Aalborg Universitet.<br>Findes også på internet (kræver læseprogrammet Acrobat Reader): http://www.sbi.dk/udgivelser/publikationer/uden%5Ffor%5Fserie/phd%5Fmiljoeproblemer/kbh%5Fphd.pdf.
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35

Carvin, Christopher Dumas. "Transcriptional regulation and chromatin remodeling mechanisms at PHO5." Diss., Texas A&M University, 2003. http://hdl.handle.net/1969.1/2193.

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Regulation of gene expression is vital for proper growth and prevention of disease states. In eukaryotes this regulation occurs in the context of chromatin which creates an inherent barrier for the binding of trans-acting factors, such as transcription factors and RNA polymerase. This dissertation focuses on the role of transcriptional activators and chromatin remodeling coactivators in the regulation of the repressible acid phosphatase gene PHO5. Our studies show that histone methylation at lysine 4 of histone H3 is required for the full repression of PHO5and GAL1-10. We show that bromodomain
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36

Jessen, Walter Joseph. "Chromatin dynamics at the Saccharomyces cerevisiae PHO5 promoter." Diss., Texas A&M University, 2004. http://hdl.handle.net/1969.1/3306.

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In eukaryotes, the organization of DNA into chromatin is a primary determinant of gene expression. Positioned nucleosomes in promoter regions are frequently found to regulate gene expression by obstructing the accessibility of cis-regulatory elements in DNA to trans-factors. This dissertation focuses on the chromatin structure and remodeling program at the S. cerevisiae PHO5 promoter, extending the use of DNA methyltransferases as in vivo probes of chromatin structure. Our studies address the diversity of histone-DNA interactions in vivo by examining nucleosome conformational stabilities at th
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37

Marden, Chloe Maria. "Functional analysis of the P47 PHOX gene promoter." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.392359.

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38

Evanshen, Pamela. "Ph.D. In Early Childhood Education: Proposed Program Update." Digital Commons @ East Tennessee State University, 2008. https://dc.etsu.edu/etsu-works/4383.

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39

O'Connor, Maria Thérèse. "Ashes without reserve PhD, 2007." Click here to access this resource online, 2007. http://hdl.handle.net/10292/393.

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40

Johns, Kristine Dawn. "Evidences for Protein-Protein Interactions Between PstB and PhoU in the Phosphate Signaling Complex of Escherichia coli." BYU ScholarsArchive, 2013. https://scholarsarchive.byu.edu/etd/3932.

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The PstSCAB2 complex serves the dual function of being a phosphate transporter as well as the primary sensor of phosphate for the Pho regulon. PhoU is an integral protein required for the signal from PstSCAB2 to be transmitted to PhoR. Our hypothesis is that conformational changes of PstSCAB2 during the phosphate transport process are the mechanism by which information about environmental phosphate levels are transduced to the cell. Additionally, we propose that direct protein-protein interactions between PhoU and the alternating conformations of PstSCAB2 mediate PhoU interactions with PhoR. B
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41

Bélanger, Étienne. "Synthèse asymétrique par voie catalytique d'alpha-fluorocétones et développement de dérivés de l'i-PR-PHOX comme équivalents pratiques du t-BU-PHOX." Thesis, Université Laval, 2011. http://www.theses.ulaval.ca/2011/28320/28320.pdf.

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Bélanger, Etienne. "Synthèse asymétrique par voie catalytique d'alpha-fluorocétones et développement de dérivés de l'iota-PR-PHOX comme équivalents pratiques du tau-BU-PHOX." Doctoral thesis, Université Laval, 2011. http://hdl.handle.net/20.500.11794/22782.

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Tableau d'honneur de la Faculté des études supérieures et postdoctorales, 2011-2012<br>Cette thèse porte sur le développement de nouvelles méthodologies de synthèse asymétrique permettant l'accès aux ct-fluorocétones. Deux nouvelles méthodes de synthèse énantiosélectives par voie catalytique d'a-fluorocétones ont été développées. La stratégie employée implique l'utilisation de précurseurs d'énolates fluorés comme nucléophiles prochiraux dans la réaction d'alkylation allylique catalysée par le palladium. En premier lieu, les éthers d'énol silylés ont été examinés dans cette réaction et une gran
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43

Bailey, Tracy. "The PhD degree : an investigation into doctoral education in South Africa and international PhD reform initiatives." Master's thesis, University of Cape Town, 2001. http://hdl.handle.net/11427/10096.

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Bibliography: leaves 181-187.<br>Since its emergence in the 1800s in Germany, the 'modern' Doctor of Philosophy (PhD) degree has been one of the cornerstones of new knowledge production and research training. Over the past two decades, there has been a surge of debate and reform around doctoral eduction internationally as a result of significant changes in both the global and local contexts within which doctoral education takes place. At the macro level, globalisation and the global economy are redefining what constitutes knowledge, who produces it and for what purposes. At the same time, more
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44

Baker, Sarah Jane. "Molecular characterisation of Salmonella typhi PhoP/Q regulated genes /." Title page, abstract and contents only, 2000. http://web4.library.adelaide.edu.au/theses/09PH/09phb1683.pdf.

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45

Ives, Glenice 1947. "The PhD supervisory relationship and process." Monash University, Faculty of Education, 2002. http://arrow.monash.edu.au/hdl/1959.1/8692.

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46

Granström, Karl. "Extended target tracking using PHD filters." Doctoral thesis, Linköpings universitet, Reglerteknik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-82348.

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The world in which we live is becoming more and more automated, exemplified by the numerous robots, or autonomous vehicles, that operate in air, on land, or in water. These robots perform a wide array of different tasks, ranging from the dangerous, such as underground mining, to the boring, such as vacuum cleaning. In common for all different robots is that they must possess a certain degree of awareness, both of themselves and of the world in which they operate. This thesis considers aspects of two research problems associated with this, more specifically the Simultaneous Localization and Map
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47

Wallach, Deborah A. (Deborah Anne). "PHD--a hierarchical cache coherent protocol." Thesis, Massachusetts Institute of Technology, 1992. http://hdl.handle.net/1721.1/12922.

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Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1992.<br>Includes bibliographical references (p. 155-157).<br>by Deborah A. Wallach.<br>M.S.
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Yang, Yan. "Academic procrastination among UK PhD students." Thesis, University of Nottingham, 2016. http://eprints.nottingham.ac.uk/37613/.

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The majority of research on academic procrastination has been conducted among undergraduate students, and there is relatively little research investigating procrastination among doctoral students. PhD students are different from undergraduates: they might need a higher level of self-regulatory ability to conduct research. The aim of this thesis was to fill the research gap in the investigation of academic procrastination among PhD students in the UK. More specifically, the current investigation combined different perspectives to examine the extent to which PhD students procrastinate, explores
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Munevar, Nicolas Federico Villamil. "Análise do metabolismo de polifosfato e do operon pst em Pseudomonas aeruginosa." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-10122015-101302/.

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O operon pst de P. aeruginosa codifica um transportador de fosfato de alta afinida-de e também a proteína PhoU que, em conjunto, atuam como repressores da ex-pressão do regulon Pho dessa espécie. A atividade de PhoU está também associada ao metabolismo de polifosfato (poliP), dado que mutantes phoU nulos apresentam um vasto acúmulo do biopolímero. Ensaios de &beta;-galactosidase mostraram uma alteração na expressão dos genes ppk e ppx, envolvidos no metabolismo de poliP, no mutante phoU. Observou-se que na cepa selvagem, a transcrição de ppk e de ppx não responde às limitações de Pi ou de nitr
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Boukhris, Ines. "Caractérisation, clonage, expression et étude de la régulation de gènes phytases de Streptomyces et Bacillus." Thesis, Université Paris-Saclay (ComUE), 2015. http://www.theses.fr/2015SACLS274.

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Les phytases hydrolysent les phytates représentant la forme majeure de stockage du P dans les céréales. Ces phytates sont aussi des facteurs anti-nutritionnels qui chélatent les cations réduisant leur absorption. Dans le premier volet de cette thèse, une nouvelle souche bactérienne produisant une phytase extracellulaire a été isolée et identifiée comme Bacillus amyloliquefaciens US573. L’enzyme «PHY US573» a été purifiée et caractérisée en comparaison avec deux phytases commerciales Ronozyme PL et Natuphos. PHY US573 se distingue par sa forte thermostabilité en présence de calcium. En outre, P
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