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Artykuły w czasopismach na temat „Plasma HbA1C”

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Data publikacji: 2 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Kapil, Deb Lahiri, Kundu Arunava, Baruah Mriganka, and Ghosh Joya. "A STUDY ON CORRELATIONS OF FASTING PLASMA GLUCOSE WITH AQUEOUS HUMOR GLUCOSE AND HBA1C IN CATARACT PATIENTS." International Journal of Basic and Applied Physiology 8, no. 1 (2019): 47–51. https://doi.org/10.5281/zenodo.4483322.

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<strong>Background & objectives</strong>: Indian guideline approved the cataract surgery with fasting plasma glucose of <140 mg/dl and random plasma glucose of less than 180mg/dl but no data on the relationship of fasting plasma glucose with aqueous glucose level and HbA1c in cataract patients was available in India. Hence our study will try to explore the relationship of fasting plasma glucose with aqueous glucose level and HbA1c in cataract patients. <strong>Methods</strong>: Thirty-six (Group A) & 40 (Group B) cataract patients with fasting plasma glucose in between 100 – 1

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Bhatti, Saeed Akram, Abdul Haseeb Khan, and Naeem Yaqoob. "GLYCATED HEMOGLOBIN (HbA1c)." Professional Medical Journal 22, no. 02 (2015): 208–14. http://dx.doi.org/10.29309/tpmj/2015.22.02.1376.

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HbA1c gives an integrated index of glycemia over the entire 120 days lifespan of red blood cells. Therefore, measuring HbA1c would be appropriate in diagnosing adisease characterized by chronic hyperglycemia and a gradual progression to complications.Objectives: our primary objective was to evaluate the use of HbA1c as screening test forundiagnosed diabetes (WHO criteria of Fasting plasma glucose (FPG) of ≥ 7mmol/l (126mg/dl))in healthy asymptomatic individuals in Pakistani population. Study Design and Methodology:A cross sectional population survey was carried on asymptomatic, healthy individ

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Hossain, Tanjina, Zafar Ahmed Latif, and Abdullah Al-mamun Sarkar. "Relationship of HbA1c with Fasting and Plasma Glucose 2 Hours after Oral Glucose Load in Non Diabetic and Newly Diagnosed Pre Diabetic and Diabetic Patients." BIRDEM Medical Journal 2, no. 2 (2012): 81–83. http://dx.doi.org/10.3329/birdem.v2i2.12307.

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Objectives: This study was conducted to assess the relationship of Fasting Plasma Glucose and Plasma Glucose 2 hours after 75 gram glucose load with HbA1c in subjects who were not detected before as diabetic, pre diabetic or non diabetic. Methods: Total eight hundred and seventy eight subjects of both sexes coming to do for an Oral Glucose Tolerance Test (OGTT) were included in the study. Fasting and plasma glucose 2 hours after 75 gram glucose load were measured by hexokinase method. HbA1c was measured by high performance liquid chromatography (HPLC) method. Results: According to OGTT among t

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Kumar, Binay, Nidhi Prasad, and Ravi Shekhar. "Post prandial glucose can be a substitute for HbA1c in low resource setting: answering the diagnostic dilemma." International Journal of Research in Medical Sciences 9, no. 2 (2021): 645. http://dx.doi.org/10.18203/2320-6012.ijrms20210460.

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Achieving a strict glycaemic control is the key factor in diabetes management and associated complications. Although A1C is the best indicator of overall glycaemic control during the previous 2-3 months and remains the gold standard for assessing glycaemic control in patients with diabetes. But in low resource setting areas where HbA1c is a costlier affair, postprandial plasma glucose estimation can be a good alternative in estimating glycaemic control. By analyzing the results from many previous papers on glycaemic profiles, we conclude that contribution of postprandial plasma glucose was rel

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Md., Abdul Malek. "Correlation of Glycated Hemoglobin with Plasma Glucose in Type 2 Diabetic Patients." International Journal of Medical and Pharmaceutical Research 4, no. 1 (2023): 171–76. https://doi.org/10.5281/zenodo.7639634.

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<strong>Background: </strong>Diabetes is a common disease in both developed and developing countries. Increasing prevalence of the disease sets the goal to aim for control of the disease process which is aimed mainly as therapy. Monitoring tool for the complications of this common disease is Glycated Hemoglobin (HbA1C). <strong>Objective: </strong>In the present retrospective study HbA1C level is correlated with both fasting and post meal plasma glucose level in type-2 diabetes mellitus patients. <strong>Methods: </strong>The retrospective study was done in Department of Biochemistry & Mol

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Batista, Raíssa A. B., Flávia M. S. de Branco, Rafaela Nehme, Erick P. de Oliveira, and Geórgia das G. Pena. "Association between Plasma Omega-3 and Handgrip Strength According to Glycohemoglobin Levels in Older Adults: Results from NHANES 2011–2012." Nutrients 14, no. 19 (2022): 4060. http://dx.doi.org/10.3390/nu14194060.

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Background: Low muscle strength is a predictor of mortality in older adults. Although the evidence concerning hyperglycemia is limited, evidence shows that omega-3 (ω-3) intake may be positively associated with muscle strength. However, the association between plasma ω-3 and muscle strength in older adults according to glycohemoglobin (HbA1c) levels has not yet been investigated. Objective: To evaluate whether plasma ω-3 levels are associated with handgrip strength in individuals over 50 years according to HbA1c levels. Methods: This cross-sectional study included 950 older adults (50–85 years

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Inada, Shinya, and Masafumi Koga. "Alcohol consumption reduces HbA1c and glycated albumin concentrations but not 1,5-anhydroglucitol." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 54, no. 6 (2016): 631–35. http://dx.doi.org/10.1177/0004563216675646.

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Background The effect of alcohol consumption on glycaemic control indicators is not well known. In this study, we studied the effect of alcohol consumption on the plasma glucose and glycaemic control indicators in non-diabetic men. Methods The study enrolled 300 non-diabetic men who received a complete medical checkup (age: 52.8 ± 6.5 years, body mass index: 24.4 ± 2.8 kg/m2). The subjects were divided into four groups by the amount of alcohol consumed, and the plasma glucose, HbA1c, glycated albumin (GA) and 1,5-anhydroglucitol (1,5-AG) concentrations of the groups were compared. Results As t

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Ansari, Shiba, Jayeeta Bhadra, Ashok Kumar Ahirwar, and Jasmeen Gupta. "Correlation analysis of HbA1c versus random, fasting, and postprandial glucose levels as predictors of glycemic control in type 2 diabetes patients." Asian Journal of Medical Sciences 14, no. 4 (2023): 37–43. https://doi.org/10.71152/ajms.v14i4.3740.

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Background: Glycated Hemoglobin (HbA1c) is used for assessing glycemic control over the past 8–12 weeks. This is critical for determining the efficacy of diabetes treatment and predicting the progression of microvascular complications. However, in health-care situations where tests for HbA1c are either unavailable or unfeasible for any reason, clinicians rely only on plasma glucose values for assessing the glycemic control of the patient. Aims and Objectives: The purpose of this study was to determine the relationship between HbA1c and fasting, postprandial, and random plasma glucose levels. M

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Ansari, Shiba, Jayeeta Bhadra, Ashok Kumar Ahirwar, and Jasmeen Gupta. "Correlation analysis of HbA1c versus random, fasting, and postprandial glucose levels as predictors of glycemic control in type 2 diabetes patients." Asian Journal of Medical Sciences 14, no. 4 (2023): 37–43. http://dx.doi.org/10.3126/ajms.v14i4.53072.

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Background: Glycated Hemoglobin (HbA1c) is used for assessing glycemic control over the past 8–12 weeks. This is critical for determining the efficacy of diabetes treatment and predicting the progression of microvascular complications. However, in health-care situations where tests for HbA1c are either unavailable or unfeasible for any reason, clinicians rely only on plasma glucose values for assessing the glycemic control of the patient. Aims and Objectives: The purpose of this study was to determine the relationship between HbA1c and fasting, postprandial, and random plasma glucose levels. M

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TUCKER, MIRIAM E. "Formula Links HbA1c to Average Plasma Glucose." Family Practice News 37, no. 21 (2007): 17. http://dx.doi.org/10.1016/s0300-7073(07)71301-4.

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Supono, Benny, and I. Wayan Putu Sutirta Yasa. "KORELASI KADAR GULA DARAH PLASMA DENGAN NILAI HBA1C PADA PASIEN DIABETES MELLITUS DI RUMAH SAKIT UMUM PUSAT SANGLAH DENPASAR BALI." E-Jurnal Medika Udayana 10, no. 9 (2021): 107. http://dx.doi.org/10.24843/mu.2021.v10.i9.p18.

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Peningkatan jumlah pasien diabetes mellitus terjadi tiap tahun dan in terjadi di seluruh dunia. Indonesia merupakan salah satu dari sepuluh negara dengan jumlah pasien diabetes terbanyak. Indonesia menempati peringkat ke tujuh dengan jumlah 10 juta pasien diabetes mellitus di tahun 2015 dan diperkirakan akan tetap terjadi peningkatan jumlah pasien diabetes mellitus pada tiap tahunnya. Diabetes dapat menyebabkan komplikasi yang beragam dari yang ringan sampai yang berat bila pasien tidak melakukan penatalaksanaan yang baik. Pemeriksaan gula darah plasma tidak cukup untuk memandu penatalaksanaan

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Bando, Yukihiro, Hideo Kanehara, Daisyu Toya, Nobuyoshi Tanaka, Soji Kasayama, and Masafumi Koga. "Association of serum glycated albumin to haemoglobin A1C ratio with hepatic function tests in patients with chronic liver disease." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 46, no. 5 (2009): 368–72. http://dx.doi.org/10.1258/acb.2009.008231.

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Background In patients with chronic liver disease (CLD), glycated haemoglobin (HbA1C) levels have been shown to be apparently lower than real values, whereas serum glycated albumin (GA) levels are apparently higher. The present study was aimed to examine whether both glycaemic indices are influenced by hepatic function. Methods Subjects consisted of 82 patients with CLD. Various indicators for hepatic function as well as HbA1C and GA were also measured. Estimated HbA1C values were calculated from the mean plasma glucose levels. Two hundred and two type 2 diabetic patients without CLD were stud

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Dworacka, Marzena, and Hanna Winiarska. "The Application of Plasma 1,5-Anhydro-D-glucitol for Monitoring Type 2 Diabetic Patients." Disease Markers 21, no. 3 (2005): 127–32. http://dx.doi.org/10.1155/2005/251068.

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Aim: Recent data have suggested that effective control of postprandial blood glucose can reduce the risk of macroangiopathic complications of diabetes, especially cardiovascular risk. 1,5-Anhydro-D-glucitol (1,5-AG) has been proposed as a marker of short-term hyperglycaemic excursions. We aimed to evaluate its usefulness in patients with type 2 diabetes and have attempted to indicate when 1,5-AG monitoring should be used in ordinary diabetes care settings. Methods: The study group consisted of 130 type 2 diabetic patients aged 36–69 years. 1,5-AG plasma level, HbA1c concentrations and daily gl

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Kyriacou, Loui, Julian Navanathan, Yanik Anthony, Abdul-Rahman Abbas, Saakshi Bansal, and Michael Albert. "An Audit on Glycosylated Haemoglobin & Fasting Plasma Glucose Blood Tests Done on Admission to an Older People's Inpatient Ward." BJPsych Open 9, S1 (2023): S166. http://dx.doi.org/10.1192/bjo.2023.440.

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AimsThe aim of this study was to determine the proportion of patients who had fasting plasma glucose and glycosylated haemoglobin (HbA1c) blood tests done on admission to an older people's inpatient ward at Kingfisher Court, Hertfordshire. Patients undergo a physical health assessment when they are admitted to the ward. This consists of a physical examination, an electrocardiogram and a panel of blood tests, which include a fasting plasma glucose and HbA1c. Given that people with severe mental illness have a greater burden of physical health conditions, such as diabetes, this physical health a

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Rahman, Md Matiur, Naila Atik Khan, Mohammad Masurn Alam, M. Iqbal Arslan, and Md Golam Hafiz. "The role of HbA1c as a diagnostic test for type 2 diabetes mellitus in Bangladesh." Bangabandhu Sheikh Mujib Medical University Journal 7, no. 2 (2016): 115. http://dx.doi.org/10.3329/bsmmuj.v7i2.29446.

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<p><strong>Background:</strong> Type 2 diabetes mellitus is a serious chronic disease with microvascular complications such as retinopathy, nephropathy and neuropathy and macrovascular complications such as cardiac, peripheral arterial and cerebrovascular disease. <strong>Objective:</strong> The aim of the study was to investigate the value of HbAlc as a diagnostic test for type 2 diabetes mellitus in Bangladeshi inclividuals. <strong>Methods:</strong> This cross sectional study was conducted in the Department of Biochemistry, Bangabandhu Sheikh Mujib

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Taiwo, EO, LO Thanni, and OP Taiwo. "Baseline Plasma Fibrinogen and Glycated Haemoglobin (HbA1c) Levels in Normoglycaemic Offspring of Adults with Type 2 Diabetes Mellitus." Annals of Health Research 8, no. 2 (2022): 99–108. http://dx.doi.org/10.30442/ahr.0802-01-161.

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Background: Type 2 Diabetes mellitus (T2DM) is known to be preceded by a long pre-diabetic stage. Family studies have confirmed that the incidence of T2DM in the first-degree offspring of T2DM patients is higher than in the non-diabetic population. The levels of plasma fibrinogen and HbA1c in offspring of T2DM patients may be markers of the development of T2DM later in life. Objectives: To determine the plasma fibrinogen and HbA1c levels of normoglycaemic offspring of T2DM patients.  Methods: This study involved randomly selected 100 offspring of T2DM patients (ODP) and 100 offspri

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Abdul-Ghani, Muhammad A., Tamam Abdul-Ghani, Gabriele Müller, et al. "Role of Glycated Hemoglobin in the Prediction of Future Risk of T2DM." Journal of Clinical Endocrinology & Metabolism 96, no. 8 (2011): 2596–600. http://dx.doi.org/10.1210/jc.2010-1698.

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Abstract Aim: The aim of this study was to assess the predictive power of glycated hemoglobin (HbA1c) for future type 2 diabetes risk. Research Design and Methods: Six hundred eighty-seven subjects who were free of type 2 diabetes mellitus (T2DM) participated in the study. Each subject received a 75-g oral glucose tolerance test at baseline and 624 received a repeat oral glucose tolerance test after 3.5 ± 0.1 yr of follow-up. Anthropometric measurements, lipid profile, and HbA1c were measured during the baseline visit. Logistic multivariate models were created with T2DM status at follow-up as

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Saudek, Christopher D., William H. Herman, David B. Sacks, Richard M. Bergenstal, David Edelman, and Mayer B. Davidson. "A New Look at Screening and Diagnosing Diabetes Mellitus." Journal of Clinical Endocrinology & Metabolism 93, no. 7 (2008): 2447–53. http://dx.doi.org/10.1210/jc.2007-2174.

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Abstract Objective: Diabetes is underdiagnosed. About one third of people with diabetes do not know they have it, and the average lag between onset and diagnosis is 7 yr. This report reconsiders the criteria for diagnosing diabetes and recommends screening criteria to make case finding easier for clinicians and patients. Participants: R.M.B. invited experts in the area of diagnosis, monitoring, and management of diabetes to form a panel to review the literature and develop consensus regarding the screening and diagnosis of diabetes with particular reference to the use of hemoglobin A1c (HbA1c)

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Verma, Niket. "A Study of HbA1c, fasting and 2 hour plasma glucose levels in current smokers presenting at a tertiary care hospital in North India." International Journal of Advances in Medicine 5, no. 1 (2018): 38. http://dx.doi.org/10.18203/2349-3933.ijam20180002.

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Background: There is a concern that smokers are at increased risk of diabetes and this association has received surprisingly little attention. This study aims to study the relationship of smoking with three glycaemic variables (HbA1c, fasting and 2 hour post prandial plasma glucose levels) in current smokers and describe the potential impact of smoking in the context of screening for diabetes by using one of these glycaemic variables.Methods: 150 patients attending the OPD of Santosh Medical College were part of this Cross sectional population based study. One hundred were smokers and fifty no

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Rosyid, Fahrun Nur, Khristophorus Heri Nugroho Hario Seno, and Ahmad Fadhlur Rahman. "Glycated albumin as medium-term glycemic control in diabetes mellitus." International Journal of Research in Medical Sciences 9, no. 12 (2021): 3739. http://dx.doi.org/10.18203/2320-6012.ijrms20214732.

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Monitoring of glucose levels is essential in preventing the complications of diabetes mellitus, including short, medium and long-term monitoring. Short-term monitoring includes random plasma glucose, fasting plasma glucose, 2-hour post prandial plasma glucose and Oral glucose tolerance tests (OGTT). The medium-term monitoring includes fructosamine and Glycated albumin (GA) while the long-term monitoring is glycated hemoglobin (HbA1c). Currently, the most recommended examination for glucose level monitoring in patients with diabetes mellitus is the glycated hemoglobin (HbA1c). However, there se

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Rahman, MR, M. Saiedullah, S. Shermin, S. Begum, and S. Hayat. "Diagnostic Efficacy of HbA1c in Diagnosis of Diabetes Mellitus in a Bangladesh Population." Bangladesh Medical Journal 41, no. 1 (2014): 53–54. http://dx.doi.org/10.3329/bmj.v41i1.18785.

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American Diabetic Association (ADA) affirms HbA1c with cut off value of 6.5% as a diagnostic criteria of diabetes mellitus. World Health Organization (WHO) also supports but recommended that a value <6.5% does not exclude diabetes which is diagnosed by glucose test. The aim of this study was to evaluate the diagnostic efficacy of HbA1c in terms of sensitivity, specificity, positive and negative predictive value and accuracy in a selected group of Bangladeshi subjects. This cross-sectional study included 761 adult Bangladeshi subjects of both sex attending the outdoor in a tertiary healthcar

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Karnchanasorn, Rudruidee, Jean Huang, Horng-Yih Ou, et al. "Comparison of the Current Diagnostic Criterion of HbA1c with Fasting and 2-Hour Plasma Glucose Concentration." Journal of Diabetes Research 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/6195494.

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To determine the effectiveness of hemoglobin A1c (HbA1c) ≥ 6.5% in diagnosing diabetes compared to fasting plasma glucose (FPG) ≥ 126 mg/dL and 2-hour plasma glucose (2hPG) ≥ 200 mg/dL in a previously undiagnosed diabetic cohort, we included 5,764 adult subjects without established diabetes for whom HbA1c, FPG, 2hPG, and BMI measurements were collected. Compared to the FPG criterion, the sensitivity of HbA1c ≥ 6.5% was only 43.3% (106 subjects). Compared to the 2hPG criterion, the sensitivity of HbA1c ≥ 6.5% was only 28.1% (110 subjects). Patients who were diabetic using 2hPG criterion but had

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Hayakawa, Tetsuo, Ken-Ichiro Kato, Shinji Kobuchi, Kaede Kataoka, and Toshiyuki Sakaeda. "Associations of Plasma Concentration Profiles of Dapagliflozin, a Selective Inhibitor of Sodium–Glucose Co-Transporter Type 2, with Its Effects in Japanese Patients with Type 2 Diabetes Mellitus." Pharmaceuticals 15, no. 2 (2022): 203. http://dx.doi.org/10.3390/ph15020203.

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This study was conducted to evaluate the long-term plasma concentration profiles of dapagliflozin and its effects on the glycated hemoglobin (HbA1c) level, body weight, and estimated glomerular filtration rate (eGFR) in 72 Japanese outpatients with type 2 diabetes mellitus (T2DM) receiving metformin and a dipeptidyl peptidase-4 inhibitor. At baseline, HbA1c level, body weight, and eGFR were 6.9 ± 0.6%, 77.9 ± 13.5 kg, and 78.8 ± 20.7 mL/min/1.73 m2, respectively. A once-daily oral dose of 5 mg dapagliflozin was administered, and its trough plasma concentrations were evaluated at 1, 3, 6, 9, an

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Prabandari, Ni Putu Sukma Sumantri, Ida Ayu Putri Wirawati, and Ni Nyoman Mahartini. "Relationship between Atherogenic Index of Plasma with HbA1c Levels in Type 2 Diabetes Mellitus Patients." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 28, no. 1 (2021): 71–74. http://dx.doi.org/10.24293/ijcpml.v28i1.1743.

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Type 2 Diabetes Mellitus (T2DM) is a global health problem due to an increasing prevalence and incidence. HbA1c as aparameter for glycemic control is still above the desired target of 7%. Atherogenic Index of Plasma (AIP) is predicted to be anindicator of cardiovascular disease risk in T2DM. Dyslipidemia in T2DM patients showed a result of increased triglycerideand decreased HDL cholesterol levels. This study aimed to determine the relationship between HbA1c and AIP, triglycerides,and HDL cholesterol in T2DM patients. An analytical observational study using a cross-sectional method on 74 DMT2p

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Tiwari, Rajlaxmi Ghangale SS Iyer CM. "STUDY OF HbA1c AS A BIOMARKER IN DYSLIPIDEMIA AND ATHEROGENICITY IN TYPE 2 DIABETES MELLITUS." International Journal of Clinical and Biomedical Research 1, no. 2 (2015): 5–11. https://doi.org/10.5281/zenodo.2532085.

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HbA1c is being used to assess the glycemic control for many years. This study was done to evaluate the importance of HbA1c in predicting dyslipidemia and atherogenecity in type 2 Diabetes. Methods: 200 type 2 diabetic patients were taken as subjects. Fasting and post meal blood sugar, Glycated haemoglobin(HbA1c), lipid profile, lipid ratios and atherogenic index of plasma(AIP) was analysed in these patients. The patients were divided into 2 groups depending on their HbA1c; Good Glycemic Control was defined as having HbA1c ≤ 7.0% and Poor Glycemic Control as HbA1c >7.0%. Results& Disc

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Rimal, Brihaspati, Fuleshwar Mandal, Deepak Kafle, and Pashupati Ranabhat. "The Relationship of Plasma Glucose Level and HbA1c among Diabetic Patients attending Chitwan Medical College." MedS Alliance Journal of Medicine and Medical Sciences 3, no. 6 (2023): 1–3. http://dx.doi.org/10.3126/mjmms.v3i6.66537.

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INTRODUCTION: Type 2 diabetes mellitus is a complex heterogeneous group of metabolic conditions characterized by an increased level of blood glucose, due to impairment in insulin action and/or insulin secretion. Normally the level of HbA1c is less than 6%. HbA1c level reveals the mean glucose level over the previous 10-12 weeks. HbA1c has become a very important part of the management of patients with diabetes mellitus. In addition, the HbA1c is a better indicator of chronic glycemic levels and has a better index to determine the risk for long-term complications as well. So for the screening o

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Zhang, Rui, Yufeng Li, Simin Zhang, Xiaoling Cai, Xianghai Zhou, and Linong Ji. "The Association of Retinopathy and Plasma Glucose and HbA1c: A Validation of Diabetes Diagnostic Criteria in a Chinese Population." Journal of Diabetes Research 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/4034129.

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Aims. This study aimed to evaluate the associations of diabetic retinopathy (DR) with fasting plasma glucose (FPG), 2-hour postload plasma glucose (2hPG), and glycated hemoglobin A1c (HbA1c) in a Chinese population.Materials and Methods. A total of 3124 participants, identified from a population-based survey in Pinggu district, were examined by retinal photography (45°). DR was classified according to the Early Treatment Diabetic Retinopathy Study scale. FPG, 2hPG, and HbA1c were tested and categorized by deciles, with the prevalence of DR calculated in each decile.Results. The prevalence of D

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GÜNGÖR, Kağan, Serkan ÖZTÜRK, Bülent CAN, and Mehmet SARGIN. "Fasting plasma c-peptide level predicts the response of glucagon-like peptide-1 agonist (exenatide) add on to metformin monotherapy in obese type 2 diabetics." Journal of Experimental and Clinical Medicine 39, no. 3 (2022): 798–802. http://dx.doi.org/10.52142/omujecm.39.3.39.

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We aimed to evaluate the ability of serum C-peptide levels to predict glycemic control in obese type 2 diabetes (T2DM) patients in which a glucagon-like peptide-1 receptor agonist (GLP1-RA), an exenatide, was added to metformin monotherapy. This was a retrospective study, in which we enrolled 44 consecutives obese, type 2 diabetic patients receiving metformin monotherapy and have inadequate glycemic control (HbA1c >7% and <10%). Twice daily GLP1-RA (10 mcg exenatide injection) was added to the treatment. Weight, height and body mass index (BMI), in addition to fasting plasma glucose, hem

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LE, Vidya, Anitha Misquith, Harish Rangareddy, Lia Maria, Jelena Stankovic, and Ashakiran Srinivasaiah. "Effect of Total Hemoglobin on Glycated Hemoglobin (HbA1c) in Type 2 Diabetes Mellitus." NATIONAL BOARD OF EXAMINATIONS JOURNAL OF MEDICAL SCIENCES 2, no. 5 (2024): 448–57. http://dx.doi.org/10.61770/nbejms.2024.v02.i05.005.

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Background: Glycated hemoglobin (HbA1c) is a pivotal marker in the diagnosis, prognosis, and therapeutic monitoring of diabetes mellitus. Given the involvement of hemoglobin in non-enzymatic glycation reactions, it is hypothesized that total hemoglobin concentration might impact HbA1c levels alongside blood glucose concentrations. Objectives: This study aimed to estimate and compare plasma fasting glucose level and total hemoglobin level in type 2 diabetes mellitus (T2DM) patients with and without anemia. The study also aimed to estimate HbA1C and compare with calculated HbA1C using formula in

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Kilpatrick, Eric S., Alan S. Rigby, and Stephen L. Atkin. "Variability in the Relationship between Mean Plasma Glucose and HbA1c: Implications for the Assessment of Glycemic Control." Clinical Chemistry 53, no. 5 (2007): 897–901. http://dx.doi.org/10.1373/clinchem.2006.079756.

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Abstract Background: Previous studies have shown a single linear relationship between mean plasma glucose (MPG) and hemoglobin A1c (HbA1c). We examined the relationship in different treatment groups of patients with type 1 diabetes participating in the Diabetes Control and Complications Trial (DCCT). Methods: Seven-point glucose profiles (premeal, postmeal, and bedtime) and HbA1c were measured quarterly during the DCCT. We studied measurements from (a) intensively treated patients at study commencement, (b) intensively treated patients after stabilization of their glycemia (from 6 months onwar

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Ahmed, Humaira, Sahar Iqbal Iqbal, Syed Talha Naeem Same, Fouzia Zeeshan Khan Same, and Uzma Nusrat Same. "Determining how the gestational changes, including low hemoglobin influence the hba1c and estimated average glucose relationship." International Journal of Pathology 22, no. 3 (2024): 125–32. http://dx.doi.org/10.59736/ijp.22.03.909.

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ABSTRACT Background: Gestational Diabetes Mellitus (GDM) affects up to 14% of pregnancies globally, with accurate glycemic control critical for preventing adverse outcomes. While HbA1c is a standard marker for long-term glucose control, its reliability in pregnant women with anemia is debated. This study explores the association between anemia and glycemic indicators (Glycosylated hemoglobin HbA1c, Random plasma glucose (rPG), and Estimated average glucose (eAG) in pregnant women with GDM. Additionally, it examined the correlation between average glucose levels or eAG, measured by random plasm

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Loh, Tze Ping, Weng Kung Peng, Lan Chen, and Sunil Kumar Sethi. "Application of smoothed continuous labile haemoglobin A1c reference intervals for identification of potentially spurious HbA1c results." Journal of Clinical Pathology 67, no. 8 (2014): 712–16. http://dx.doi.org/10.1136/jclinpath-2014-202346.

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AimsWe aim to develop smoothed continuous 2.5th and 97.5th percentile values for labile glycated haemoglobin A1c to glycated haemoglobin A1c (LHbA1c:HbA1c) ratio against HbA1c, and apply them on our patient population for identification of potentially spurious HbA1c measurements.MethodsThe LHbA1c and HbA1c were measured using Bio-rad Variant II high-performance liquid chromatography system. We recorded the LHbA1c and HbA1c values of 1555 patients who had normal chromatograms. Using these results, the 2.5th and 97.5th percentile reference limits of the LHbA1c:HbA1c ratio were described by LHbA1

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Almaimani, Riyad. "The Association between oxidative stress marker Beta-2 microglobulin and type 2 diabetes mellitus in context of glycaemic index." Journal of Umm Al-Qura University for Medical Sciences 7, no. 1 (2021): 28–31. http://dx.doi.org/10.54940/ms74813000.

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Beta-2 microglobulin (B2M) protein has been shown to be elevated in response to oxidative stress and metabolic disorders and it modulates human immune and inflammatory responses. However, little is known about the association between B2M and glycaemic index in diabetic patients. Hence, this case-control study was conducted to measure the effects of type 2 diabetes mellitus (T2DM) on the plasma concentrations of B2M. A total of 50 T2DM male patients alongside another 50 age-matched and healthy men were enrolled. The plasma concentrations of B2M and haemoglobin A1c (HbA1c) were measured. Data re

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Maajani, Khadije, Ensieh Nasli-Esfahani, Noushin Fahimfar, Ali Sheidaei, Mohammad Ali Mansournia, and Kamran Yazdani. "Long-term glycemic variability and the risk of cardiovascular diseases in type 2 diabetic patients: Effect of hypothetical interventions using parametric g-formula in a population-based historical cohort study." PLOS One 20, no. 5 (2025): e0319975. https://doi.org/10.1371/journal.pone.0319975.

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Background Harmful effects of long-term HbA1c and fasting plasma glucose (FPG) variability on cardiovascular diseases (CVD) have not been causally examined. We employed a parametric g-formula to estimate the causal effect of HbA1C and fasting plasma glucose (FPG) variability on CVD. Methods This retrospective cohort study was conducted on 2078 patients with type 2 diabetes who were free of CVD and aged >18 years at the entrance to the clinic (2017–2022), with at least three HbA1c and FPG measurements. Variability was calculated using standard deviation (SD), and coefficient of variation (CV

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Amidu, Nafiu, William Kwame Boakye Ansah Owiredu, Lawrence Quaye, Peter Paul Mwinsanga Dapare, and Yussif Adams. "Comparative Abilities of Fasting Plasma Glucose and Haemoglobin A1c in Predicting Metabolic Syndrome among Apparently Healthy Normoglycemic Ghanaian Adults." International Journal of Chronic Diseases 2019 (July 24, 2019): 1–8. http://dx.doi.org/10.1155/2019/2578171.

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There are arguments as to whether haemoglobin A1c (HbA1c) better predicts Metabolic syndrome (MetS) than fasting plasma glucose. The aim of the study was to explore the comparative abilities of HbA1c and Fasting plasma glucose (FPG) in predicting cardiometabolic risk among apparently healthy adults in the Tamale metropolis. This study was a cross-sectional study conducted in the Tamale metropolis from September, 2017, to January, 2018, among one hundred and sixty (160) apparently healthy normoglycemic adults. A self-designed questionnaire was administered to gather sociodemographic data. Anthr

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Sitasuwan, Tullaya, and Raweewan Lertwattanarak. "Prediction of type 2 diabetes mellitus using fasting plasma glucose and HbA1c levels among individuals with impaired fasting plasma glucose: a cross-sectional study in Thailand." BMJ Open 10, no. 11 (2020): e041269. http://dx.doi.org/10.1136/bmjopen-2020-041269.

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ObjectivesAbout 11%–30% of individuals with impaired fasting plasma glucose (IFG) have type 2 diabetes mellitus (T2DM), diagnosed by the 75 g oral glucose tolerance test (75 g OGTT). This study investigated (1) the prevalence and cut-off levels for fasting plasma glucose (FPG) and glycated haemoglobin A1c (HbA1c) in IFG individuals that most effectively predict the presence of T2DM diagnosed by a 75 g OGTT; (2) the predictors associated with T2DM; and (3) the pathophysiological characteristics of patients with IFG.Materials and methodsA single-centre, cross-sectional study was conducted in a p

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Yordanov, E., E. Hristov, I. Parvova, V. Petkova, and K. Andreevska. "Diagnostic and Prognostic Value of Glycated Hemoglobin (HbA1c) in Patients with Diabetes Mellitus and Thalassemia." Acta Medica Bulgarica 47, no. 3 (2020): 13–17. http://dx.doi.org/10.2478/amb-2020-0027.

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AbstractDiabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia, which is caused by impaired insulin secretion, insulin action, or both. Four complications of DM have been identified – diabetes microangiopathy including nephropathy, retinopathy and polyneuropathy and diabetes macroangiopathy. DM is diagnosed on the basis of one of the following criteria: 1. Presence of typical symptoms – polyuria, polyphagia, polydipsia, weight loss and accidental plasma glucose value ≥ 11.1 mmol/l. 2. Fasting plasma glucose level ≥ 7.0 mmol/l. 3. Oral Glucose Tolerance Test (OGTT) – 2-hou

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Lindarto, Dharma, Santi Syafril, and Dairion Gatot. "The Correlation between Glycemic Characteristic and Erythrocyte Indices in Obesity." Indonesian Biomedical Journal 8, no. 3 (2016): 176. http://dx.doi.org/10.18585/inabj.v8i3.215.

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BACKGROUND: Elevated blood glucose level is a major factor in development of diabetic complications due to unfavorable hyperglycemic induced biochemical as well as hematological indices changes. The aim of this study was to evaluate the correlation between glycemic characteristic and erythrocyte indices in obese subjects with different glycemic status.METHODS: Cross cross-sectional study was designed, and 80 obese subjects were enrolled. The correlations between glycemic characteristic (fasting plasma glucose (FPG), postprandial plasma glucose (PPG), hemoglobin A1c (HbA1c) and homeostasis mode

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Yu, Elaine A., Peter J. Hu, and Saurabh Mehta. "Plasma fatty acids in de novo lipogenesis pathway are associated with diabetogenic indicators among adults: NHANES 2003–2004." American Journal of Clinical Nutrition 108, no. 3 (2018): 622–32. http://dx.doi.org/10.1093/ajcn/nqy165.

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ABSTRACT Background Insulin regulates fatty acids (FAs) in the blood; conversely, FAs may mediate insulin sensitivity and are potentially modifiable risk factors of the diabetogenic state. Objective The objective of our study was to examine the associations between plasma concentrations of FAs, fasting plasma glucose (FPG), and glycated hemoglobin (HbA1c) among individuals (n = 1433) in the NHANES (2003–2004). Design Plasma concentrations of 24 individual FAs were considered individually and in subgroups, per chemical structure. Study participants were categorized in diabetogenic groups: Group

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Thamakaison, Sangsulee, Thunyarat Anothaisintawee, Kanokporn Sukhato, et al. "Hemoglobin A1c in combination with fasting plasma glucose trumps fasting plasma glucose alone as predictive indicators for diabetes mellitus: an ambidirectional cohort study of Thai people with impaired fasting glucose." BMJ Open Diabetes Research & Care 9, no. 2 (2021): e002427. http://dx.doi.org/10.1136/bmjdrc-2021-002427.

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IntroductionThis ambidirectional cohort study aimed to assess the performance of combining hemoglobin A1c (HbA1c) to fasting plasma glucose (FPG) for estimation of progression rate to diabetes mellitus (DM) and to explore the risk factors of DM in patients with impaired fasting glucose (IFG).Research design and methodsPatients with IFG were eligible for this study. IFG was defined as FPG of 100–125 mg/dL. Progression rates to DM were estimated using Kaplan-Meier analysis. Risk factors of DM were explored by Cox regression analysis.Results3011 patients were enrolled with median follow-up time o

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Verdam, Froukje J., Jan Willem M. Greve, Sedigheh Roosta, et al. "Small Intestinal Alterations in Severely Obese Hyperglycemic Subjects." Journal of Clinical Endocrinology & Metabolism 96, no. 2 (2011): E379—E383. http://dx.doi.org/10.1210/jc.2010-1333.

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abstract Context: Type 2 diabetes mellitus (DM2) is associated with small intestinal hyperplasia and hypertrophy in rodents. Moreover, the small intestine is increasingly acknowledged to play a role in the pathophysiology of DM2. Objective: The objective of the study was to investigate the relation between plasma markers of small intestinal function and chronic hyperglycemia in man. Design, Setting, and Participants: We conducted a cross-sectional observational study of 40 severely obese subjects with chronic hyperglycemia and 30 severely obese subjects without chronic hyperglycemia who were i

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Pangaluri, Renuka, Somnath Bag, and Vinodhini V. M. "Hemorheological Indices and Glycated Hemoglobin in Type 2 Diabetes Mellitus." Biomedical and Pharmacology Journal 13, no. 4 (2020): 1899–902. http://dx.doi.org/10.13005/bpj/2066.

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The use of HbA1c in diagnosis of diabetes mellitus by WHO and ADA has come under scrutiny. Aim: To study the erythrocyte index alterations and their relationship with HbA1c for proper interpretation of HbA1c values in diabetic subjects. Materials and methods: Data from 301 diabetic patients was collected. The parameters included were fasting plasma glucose, red blood cell count, hemoglobin level, hematocrit, glycated Hemoglobin (HbA1c), MCV, MCH, MCHC and RDW. Results: A negative correlation was found between HbA1c and MCV, MCH and MCHC and positive correlation with RDW. Conclusion: Hematologi

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Yang, Chun-Pai, Chia-Ing Li, Chiu-Shong Liu, et al. "Variability of fasting plasma glucose increased risks of diabetic polyneuropathy in T2DM." Neurology 88, no. 10 (2017): 944–51. http://dx.doi.org/10.1212/wnl.0000000000003682.

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Objective:To examine whether variations in fasting plasma glucose (FPG), as measured by the coefficient of variation (CV), is a predictor of diabetic polyneuropathy (DPN) risk, considering glycated hemoglobin (HbA1c) and other traditional risk factors.Methods:Type 2 diabetic patients enrolled in the National Diabetes Care Management Program were ≥30 years of age and free of DPN (n = 36,152). They were enrolled in 2002–2004 and were monitored until 2011. The related factors were analyzed using Cox proportional hazards regression models.Results:During an average 7.23 years of follow-up, a total

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Ollerton, R. L., S. D. Luzio, and D. R. Owens. "Contribution of fasting and postprandial plasma glucose to HbA1c." Diabetic Medicine 22, no. 7 (2005): 954–55. http://dx.doi.org/10.1111/j.1464-5491.2005.01559.x.

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Şerban, V., A. Enache, A. Lǎcǎtuşu, H. Schüszler, E. Szakacs, and M. Şerban. "Relationship between serum fructosamine, HbA1c and fasting plasma glucose." Diabetes Research and Clinical Practice 50 (September 2000): 412. http://dx.doi.org/10.1016/s0168-8227(00)81404-7.

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Khandhedia, Parth, Karan Sharma, and Ramesh Pradhan. "Significance of diagnostic and monitoring criterion of HbA1c as compared with fasting and 2-hour plasma glucose concentration in GCS general hospital, Ahmedabad: a retrospective study." International Journal of Research in Medical Sciences 10, no. 4 (2022): 850. http://dx.doi.org/10.18203/2320-6012.ijrms20220976.

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Background: Diabetes is a chronic disorder that has reached epidemic levels. Its complications are potentially life-threatening but can be slowed by early diagnosis and treatment. Complications develop earlier in patients having more fluctuating levels of blood glucose than those having maintained levels. Early diagnosis and treatment confer more benefits than aggressive control.Methods: As it was a retrospective study; the data was collected from available records of patients in whom all the three tests have been executed and analysed using SPSS version 26.Results: Diabetics were 199 (53.9%)

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Ozdemir, Ozlem, Tevfik Noyan, Abdullah Uner, and Cagri Akalin. "Evaluation of interleukin-33 and osteopontin levels in well and poorly regulated diabetes mellitus type 2." Medicine Science | International Medical Journal 13, no. 2 (2024): 315. http://dx.doi.org/10.5455/medscience.2024.02.014.

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IL-33 is one of the novel IL-1 family members which are secreted in many tissues. Osteopontin (OPN) is a highly phosphorylated and glycosylated sialoprotein synthesized primarily in bone tissue, which the major role is to participate in biomineralization. Both IL-33 and OPN are mentioned associated with inflammatory disorders. Diabetes Mellitus Type 2 (T2DM) is a metabolic disorder in glucose homeostasis, which its pathophysiology involves a low-grade chronic inflammation. The aim of this study is to evaluate the IL-33 and OPN levels in well and poorly regulated T2DM patients. Three group were

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van der Vaart, Amarens, Martine G. E. Knol, Martin H. de Borst, et al. "The Paradoxical Role of Circulating Ketone Bodies in Glycemic Control of Individuals with Type 2 Diabetes: High Risk, High Reward?" Biomolecules 12, no. 9 (2022): 1318. http://dx.doi.org/10.3390/biom12091318.

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Introduction: Fasting plasma ketone bodies (KB) are elevated in individuals with type 2 diabetes (T2D) and could affect glycemic control and disease progression. Prolonged KB exposure may result in adaptive beneficial responses, counteracting glycemic dysregulation. In the current proof-of-concept study in adults with T2D, we hypothesized that fasting plasma KB are cross-sectionally associated with poorer glycemic control but prospectively with better glycemic control. Materials and Methods: Fasting plasma KB were measured via nuclear magnetic resonance spectroscopy in patients with T2D treate

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Alzahrani, Sami Hamdan, Mukhtiar Baig, Khaled A. Yaghmour, and Sarah Al Muammar. "Determinants of Vitamin D deficiency among type 2 diabetes mellitus patients: A retrospective study." Medicine 103, no. 8 (2024): e37291. http://dx.doi.org/10.1097/md.0000000000037291.

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Recent studies have shown an association between vitamin D deficiency (VDD) and type 2 diabetes mellitus patients (T2DM), but the precise relationship between these conditions has yet to be clarified. In this study, we aimed to estimate the incidence of VDD among diabetic patients and identify any relationship between diabetes and the determinants of VDD among T2DM individuals. A retrospective cross-sectional study was conducted at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Patients of either gender were selected from electronic records and checked for vitamin D levels, glycosyl

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Ahn, Moon Bae, Kyoung Soon Cho, Seul Ki Kim, et al. "Poor Glycemic Control Can Increase the Plasma Kidney Injury Molecule-1 Concentration in Normoalbuminuric Children and Adolescents with Diabetes Mellitus." Children 8, no. 5 (2021): 417. http://dx.doi.org/10.3390/children8050417.

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Diabetic nephropathy (DN) is a serious microvascular complication in childhood diabetes and microalbuminuria has been a solid indicator in the assessment of DN. Nevertheless, renal injury may still occur in the presence of normoalbuminuria (NA) and various tubular injury biomarkers have been proposed to assess such damage. This case-controlled study aimed to evaluate plasma and urinary neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 (KIM-1) levels in diabetic children particularly in those with normo- and high-NA stages and determine their role in predicting DN. Fifty-f

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