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Artykuły w czasopismach na temat „Pleomorphic malignant fibrous histiocytoma”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Fletcher, Christopher D. M. "Pleomorphic Malignant Fibrous Histiocytoma." American Journal of Surgical Pathology 16, no. 3 (1992): 213–28. http://dx.doi.org/10.1097/00000478-199203000-00001.

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M Kiran, M., M. Karaman, F. Hatipoglu, and Y. Koc. "Malignant fibrous histiocytoma in a dog: a case report." Veterinární Medicína 50, No. 12 (2012): 553–57. http://dx.doi.org/10.17221/5665-vetmed.

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In this report, a case of malignant fibrous histiocytoma involving skin, lungs, kidneys, pancreas and mediastinal lymph node was described. Microscopically, the tumor classified as storiform-pleomorphic type malignant fibrous histiocytoma.

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Martha, Lilia Tena-Suck, Sánchez-Garibay Carlos, and Salinas-Lara Citlaltepelt. "Intracranial Pleomorphic Malignant Fibrous Histiocytoma, Associated to Systemic Lupus Erythematous: A Case Report." British Journal of Medicine & Medical Research 21, no. 9 (2017): 1–9. https://doi.org/10.9734/BJMMR/2017/32743.

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<strong>Background:</strong> Pleomorphic Malignant Fibrous histiocytoma (MFH) is a rare neoplasms of the soft tissue and bone composed of fibroblastic and histiocytic components with mitosis figures, nuclear pleomorphism and anaplasia. <strong>Case Presentation:</strong> We presented a rare case of MFH in 44 year old woman with history of systemic erythematosus lupus and seizures. Treated with prednisone. The cerebral TAC showed a temporal mass. Craniotomy was performed and the examination of the biopsy sample revealed a giant, pleomorphic and atypical cells. Immunohistochemical analysis showe

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4

Bajaj, Anubha. "The Vascular Swirls- Angiomatoid Fibrous Histiocytoma." Journal of Clinical and Diagnostic Pathology 1, no. 3 (2021): 15–23. http://dx.doi.org/10.14302/issn.2689-5773.jcdp-20-3648.

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Angiomatoid fibrous histiocytoma (AFH) is an exceptional, soft tissue neoplasm of indeterminate lineage and intermediate malignancy associated with minimal localized tumour reoccurrence and infrequent distant metastasis. Preliminarily contemplated to be a variant or derivative of malignant fibrous histiocytoma or undifferentiated pleomorphic sarcoma or an unusual fibrohistiocytic sarcoma, angiomatoid fibrous histiocytoma predominantly incriminates young po pulation and superficial sites although several extra-somatic sites can be implicated.

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Bajaj, Anubha. "The Vascular Swirls- Angiomatoid Fibrous Histiocytoma." Journal of Clinical and Diagnostic Pathology 1, no. 3 (2021): 15–23. http://dx.doi.org/10.14302/issn.2689-5773.jcdp-20-3648.

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Angiomatoid fibrous histiocytoma (AFH) is an exceptional, soft tissue neoplasm of indeterminate lineage and intermediate malignancy associated with minimal localized tumour reoccurrence and infrequent distant metastasis. Preliminarily contemplated to be a variant or derivative of malignant fibrous histiocytoma or undifferentiated pleomorphic sarcoma or an unusual fibrohistiocytic sarcoma, angiomatoid fibrous histiocytoma predominantly incriminates young po pulation and superficial sites although several extra-somatic sites can be implicated.

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6

ÖZEN, Η., S. DAĞ, E. KARAKURT, and E. BÜYÜK. "Malignant fibrous histiocytoma in a budgerigar (Melopsittacus undulatus)." Journal of the Hellenic Veterinary Medical Society 71, no. 3 (2020): 2407. http://dx.doi.org/10.12681/jhvms.25105.

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In this report, a case of malignant fibrous histiocytoma in a budgerigar (Melopsittacus undulatus) is described. At necropsy, a tumorous subcutaneous mass was noted to be located under the right wing at the level of humerus in a budgerigar. On microscopic examination, the tumor was composed of pleomorphic cells having mostly round to oval large nucleus. Presence of occasional bands composed of fibroblastoid cells were noted. Occasional giant cells and mitotic figures were also observed. Based on the microscopic findings, a diagnosis of malignant fibrous histiocytoma was made. The present case

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7

Letayf, Sonia Lopez, Ana María Cano Valdez, Beatriz Catalina Aldape Barrios, and Gerardo Jasso Romero. "Pleomorphic Undifferentiated Sarcoma (Malignant Fibrous Histiocytoma)." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 119, no. 3 (2015): e164. http://dx.doi.org/10.1016/j.oooo.2014.07.275.

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Dilek, T. U. K., S. Dilek, O. Pata, C. Tataroglu, and E. Tok. "Malignant fibrous histiocytoma of the ovary: a case report." International Journal of Gynecologic Cancer 16, Suppl 1 (2006): 352–56. http://dx.doi.org/10.1136/ijgc-00009577-200602001-00062.

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Malignant fibrous histiocytoma is the most common type of soft tissue sarcoma in adults. Primary malignant fibrous histiocytoma of the ovary is extremely rare, with only three previously reported cases. We reported a rare and uncommon localization of malignant fibrous histiocytoma in a 22-year-old woman. She was referred for adjuvant chemotherapy to our center with the diagnosis of storiform-pleomorphic malignant fibrous histiocytoma. A left adnexal mass was detected by computed tomography of the lower abdomen. Therefore, we decided to perform reoperation for debulking, and left salpingo-oophe

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Nguyen, Austin, Adam Vaudreuil, Paul Haun, Gabriel Caponetti, and Christopher Huerter. "Clinical Features and Treatment of Fibrous Histiocytomas of the Tongue: A Systematic Review." International Archives of Otorhinolaryngology 22, no. 01 (2017): 094–102. http://dx.doi.org/10.1055/s-0037-1602819.

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Introduction Benign fibrous histiocytomas are common lesions of the skin that rarely affect the tongue. Such cases are available in the literature exclusively as case reports. Similarly, malignant fibrous histiocytoma, now classified as undifferentiated pleomorphic sarcoma, is exceedingly rare in the tongue and not fully understood. Objectives This study systematically reviews the available literature discussing the clinical and pathological features of malignant and benign fibrous histiocytomas. Data Synthesis A total of 20 cases were included in this review. Patient-level data were extracted

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., Shubham, Ashokan Ravi, and Haridarshan S. J. "Anterior abdominal wall spindle cell tumour - atypical fibrous histiocytoma: a rare presentation." International Surgery Journal 5, no. 10 (2018): 3450. http://dx.doi.org/10.18203/2349-2902.isj20184109.

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Atypical fibrous histiocytoma is a rare and a distinct variant of cutaneous fibrous histiocytoma which can be misdiagnosed as sarcoma. It is mainly composed of a mixture of fibroblastic and histiocytic cells, especially found in the skin (dermatofibroma), particularly in the limbs. It is quite uncommon and is difficult to distinguish from a malignant lesion. Due to the lack of clear cut predictive morphological patterns and due to the suspicion of malignancy, complete surgical excision is recommended. Provided that atypical fibrous histiocytoma is treated by complete excision, a benign outcome

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11

Bhardwaj, Rohit, Ankur Gupta, Sabarirajan Ponnusamy, and Karthika Nathan. "Pleomorphic Undifferentiated Sarcoma (Malignant Fibrous Histiocytoma) of True Vocal Fold: A Rare Laryngeal Malignancy." Bengal Journal of Otolaryngology and Head Neck Surgery 28, no. 1 (2020): 84–87. http://dx.doi.org/10.47210/bjohns.2020.v28i1.179.

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Introduction Pleomorphic undifferentiated sarcoma also known as Malignant fibrous histiocytoma, is a malignanat tumour which commonly involves upper and lower extremities and the retroperitoneum. Only a few sporadic MFHs located in the head and neck have been reported in the literature. Rarely the tumor can involve larynx. Complete excision of the tumor is the standard treatment but post-operative chemotherapy and / or radiotherapy is also recommended in selected cases. Case Report We present a rare case report of pleomorphic undifferentiated sarcoma also known as malignanat

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12

García Alvarez, C., R. J. González Alvarez, A. C. Plata Bello, H. Alvarez-Argüelles Cabrera, and T. Concepción Masip. "Pleomorphic malignant fibrous histiocytoma in bladder diverticulum." Urology Case Reports 28 (January 2020): 101074. http://dx.doi.org/10.1016/j.eucr.2019.101074.

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Aljariri, Adham A., Abdulrahman R. Alsaleh, Hussain A. Al-Enazi, et al. "Glottic Malignant Fibrous Histiocytoma: A Case Report and Literature Review." Case Reports in Oncology 14, no. 1 (2021): 641–46. http://dx.doi.org/10.1159/000514977.

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Pleomorphic sarcoma of the larynx is a rare variant of laryngeal cancer. We present the case of a 59-year-old male patient who has been smoking for 40 years. He presented with signs and symptoms of an obstructive glottic mass. The diagnostic workup pointed to a malignant pathology; the histopathology report confirmed the diagnosis of glottic undifferentiated pleomorphic sarcoma (malignant fibrous histiocytoma).

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14

Magro, G., M. Lopes, M. Cosentino, and V. Cosentino. "Pleomorphic Malignant Fibrous Histiocytoma of the Spermatic Cord: An Unusual Site for Such a Tumor." Urologia Journal 70, no. 1-4 (2003): 32–34. http://dx.doi.org/10.1177/039156030307001-406.

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15

Cormio, Luigi, Francesca Sanguedolce, Paolo Massenio, et al. "Long-Term Results of Radical Surgery and Adjuvant Radiotherapy in a Case of Primary Malignant Fibrous Histiocytoma of the Kidney." Open Urology & Nephrology Journal 7, no. 1 (2014): 1–3. http://dx.doi.org/10.2174/1874303x01407010001.

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Malignant fibrous histiocytoma of the kidney is an extremely rare tumor that isthought to arise from the renal capsule. Radical nephrectomy is the standard treatment for localized disease but 25% of patients die of metastatic disease despite radical surgical resection. In the absence of clear pathogenetic information, adjuvant treatment remains empiric. Herein, we describe the case of a previously healthy 58-year-old woman who underwent radical nephrectomy because of 8-cm solid lesion of the right kidney; pathology revealed a pleomorphic malignant fibrous histiocytoma invading the perinephric

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16

Seo, Ill Young, Tae Hoon Oh, Keum Ha Choi, and Sarantulga Chuluun. "Pleomorphic malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma of the glans penis." Canadian Urological Association Journal 7, no. 11-12 (2013): 823. http://dx.doi.org/10.5489/cuaj.1052.

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Primary sarcoma of the penis has an extremely low incidence, and its diagnosis and treatment are unclear. A 55-year-old man presented with an oval-shaped mass of the glans penis, which was treated by a wide excision. The pathologic result revealed an undifferentiated high-grade sarcoma, which was diagnosed as a pleomorphic malignant fibrous histiocytoma/undifferentiated pleomorphic sarcoma based on the World Health Organization classification. There was no recurrence at the 12-months postoperative follow-up.

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17

Petrovic, Sonja, Nikola Andjelic, Milan Popovic, Borislava Nikolin, and Natasa Prvulovic-Bunovic. "Undifferentiated pleomorphic retroperitoneal sarcoma: A case report." Medical review 73, no. 5-6 (2020): 183–87. http://dx.doi.org/10.2298/mpns2006183p.

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Introduction. Undifferentiated pleomorphic sarcoma, previously known as malignant fibrous histiocytoma, is the most common soft tissue sarcoma in adults, and retroperitoneum is the second most common location. Case Report. We present a case of a 60-year-old female patient with a painless mass in the left hemiabdomen. Computed tomography revealed a well defined retroperitoneal mass, while magnetic resonance showed a lobulated hypointense mass on T1-weighted and heterogeneous on T2-weighted images 180 x 230 x 250 mm in size, with intense peripheral enhancement. The patient underwent complete tum

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18

Wang, Jigang, Yanxia Jiang, Yuewei Wang, et al. "Primary pleomorphic malignant fibrous histiocytoma of the heart." Acta Histochemica 115, no. 7 (2013): 761–66. http://dx.doi.org/10.1016/j.acthis.2013.02.001.

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19

Upasham, Pragati S., Sharayu P. Dighavkar, and Prakash M. Roplekar. "Undifferentiated pleomorphic sarcoma: Diagnosis of exclusion." Asian Journal of Oncology 03, no. 02 (2017): 133–35. http://dx.doi.org/10.4103/asjo.asjo_34_17.

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AbstractMalignant soft-tissue tumors which were designated as malignant fibrous histiocytoma are regrouped by the WHO (in 2002) under the new entity termed as “undifferentiated pleomorphic sarcoma.”1 It accounts for less than 5% of all adult soft-tissue sarcomas. Here, we report the lesion in a 70-year-old man who presented with high-grade undifferentiated pleomorphic sarcoma in the lower extremity.

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Katsourakis, Anastasios, George Noussios, Iosif Hadjis, Neofitos Evangelou, and Efthimios Chatzitheoklitos. "Primary Malignant Fibrous Histiocytoma: A Rare Case." Case Reports in Medicine 2011 (2011): 1–3. http://dx.doi.org/10.1155/2011/134801.

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Malignant fibrous histiocytoma (MFH) of the small intestine is an extremely rare condition. It occurs most commonly in the extremities and the trunk. We report a case of a 67-year-old woman who admitted with fever, myalgia, and altered status. After thorough investigation, a tumor of the jejunum was found. The patient underwent complete surgical removal of the tumor. A diagnosis of MFN (undifferentiated high-grade pleomorphic sarcoma) was made. The patient received adjuvant chemotherapy with Gemcitabine. Two years after the operation, the patient died due to recurrence of the disease. MFH of t

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21

Suri, Rajendar Krishan, Ratna S. Manjari, Neerod Kumar Jha, Vaiphei Kim, Rajnish Juneja, and Mandeep Singh. "Malignant Fibrous Histiocytoma of the Left Atrium." Asian Cardiovascular and Thoracic Annals 4, no. 4 (1996): 230–32. http://dx.doi.org/10.1177/021849239600400411.

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A 25-year-old female presented with symptoms resembling those of critical mitral stenosis. Echocardiography revealed a left atrial mass without a stalk, which was suspected to be a left atrial myxoma. An irregular soft friable mass was found at surgery. It measured 10 × 8 cm, with finger-like extensions and occupied almost the entire left atrial cavity, extending into the three tributaries of the right pulmonary vein. Histopathology of the excised tumor including electron microscopy showed a pleomorphic cytology interlaced with bundles, areas of necrosis, and occasional bizarre tumor giant cel

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Hansch, Neumann, Gajda, Marintchev, Pfeil, and Mayer. "Transarterial catheter embolization of a sarcoma for preoperative conditioning." Vasa 39, no. 2 (2010): 185–88. http://dx.doi.org/10.1024/0301-1526/a000026.

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This paper presents a case of an undifferentiated pleomorphic sarcoma/NOS (not otherwise specified; former pleomorphic - storiform malignant fibrous histiocytoma) of the lower leg, of a huge tumor causing ulceration of the cutaneous surface. To improve preoperative conditions, selective transarterial devascularization of the tumor feeders was performed. At operation the tumor was completely ischaemic allowing for clear tumor demarcation with little blood loss during surgery.

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Pavlovic, Mladen, Bojan Milosevic, Dragce Radovanovic, et al. "Malignant fibrous histiocytoma of the right upper leg: A case report." Vojnosanitetski pregled 75, no. 3 (2018): 320–25. http://dx.doi.org/10.2298/vsp160512237p.

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Introduction. Malignant fibrous histiocytoma is a fast spreading pleomorphic sarcoma with a high malignant potential. Its spreading is characterized with local invasion and distant metastazes with early onset. Most common localisations of development are extremities, trunk and retroperitoneum. Given the line of rare case and specimen, lack of a clear etiology and mechanisms of this disease, as well as adequate histopathologic findings and intraoperative documentation, we presented current status, discuss putative etiology, histopathology with variant morphology, differential diagnosis and trea

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Al-Agha, Osama M., and Anne A. Igbokwe. "Malignant Fibrous Histiocytoma: Between the Past and the Present." Archives of Pathology & Laboratory Medicine 132, no. 6 (2008): 1030–35. http://dx.doi.org/10.5858/2008-132-1030-mfhbtp.

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Abstract The precise nature and diagnostic concept of malignant fibrous histiocytoma (MFH) has been debated for years. Currently, a histiocytic lineage of the tumor cells is no longer favored. The nomenclature and classification of MFH and its subtypes have also been changed. The MFH pattern, especially that of storiform-pleomorphic variant, is viewed as a morphologic pattern shared by a number of sarcomas as well as by other nonsarcomas. Therefore, a diagnosis of MFH based solely on morphology is no longer acceptable and identification of a line of differentiation should be sought. A diagnosi

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Westermann, Frederieke N., Neil E. I. Langlois, and John G. Simpson. "Apoptosis in Atypical Fibroxanthoma and Pleomorphic Malignant Fibrous Histiocytoma." American Journal of Dermatopathology 19, no. 3 (1997): 228–31. http://dx.doi.org/10.1097/00000372-199706000-00005.

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Zhurakivska, Khrystyna, Giuseppe Troiano, Marco Montella, et al. "Oral Health and Molecular Aspects of Malignant Fibrous Histiocytoma Patients: A Systematic Review of the Literature." International Journal of Environmental Research and Public Health 17, no. 4 (2020): 1426. http://dx.doi.org/10.3390/ijerph17041426.

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Malignant fibrous histiocytoma is one of the most common soft tissue sarcomas in adults. It occurs only occasionally in oral soft tissues, and knowledge about its characteristics is based on a limited number of cases reported in the literature. Malignant fibrous histiocytoma belongs to the group of soft tissue sarcomas and makes up less than 10% of soft tissue sarcomas. For therapeutic purposes, complete exeresis of the lesion (macroscopic and microscopic) is performed because they have frequent recurrences. As for complementary therapy in addition to surgery, neither radiotherapy nor chemothe

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Brim, SP, TJ Allerding, and K. Buck. "Pleomorphic hyalinized angiectatic tumor of soft parts." Journal of the American Podiatric Medical Association 89, no. 6 (1999): 307–11. http://dx.doi.org/10.7547/87507315-89-6-307.

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Pleomorphic hyalinized angiectatic tumor of soft parts is a recently described neoplasm that most commonly affects the lower extremities. It is locally aggressive but has not been known to metastasize. This article presents a case of a softball-sized tumor on the dorsum of the foot that was identified as pleomorphic hyalinized angiectatic tumor of soft parts. Previously, it would have been misdiagnosed and treated as either a neurilemoma or a malignant fibrous histiocytoma.

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Sakamoto, Akio, Yoshinao Oda, Toshisada Adachi та ін. "β-Catenin Accumulation and Gene Mutation in Exon 3 in Dedifferentiated Liposarcoma and Malignant Fibrous Histiocytoma". Archives of Pathology & Laboratory Medicine 126, № 9 (2002): 1071–78. http://dx.doi.org/10.5858/2002-126-1071-caagmi.

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Abstract Context.—β-Catenin is an adhesion molecule that also plays a role in the Wnt signaling pathway. Objective.—To analyze β-catenin mutation and accumulation in a series of liposarcomas and malignant fibrous histiocytomas. Design.—β-Catenin mutation in exon 3 was studied using polymerase chain reaction–single-strand conformation polymorphism (PCR-SSCP) and direct sequencing analysis in 30 formalin-fixed, paraffin-embedded liposarcomas. The tumors included 12 dedifferentiated liposarcomas, characterized by both high-grade anaplastic components and well-differentiated liposarcoma components

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Suri, Rajendar Krishan, Raghuvir Singh Kanwar, Harjinder Singh, et al. "Cardiac Tumors: Surgical Experience in Thirty-Nine Cases." Asian Cardiovascular and Thoracic Annals 4, no. 1 (1996): 14–17. http://dx.doi.org/10.1177/021849239600400103.

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Over a period of 18 years, 39 cases of cardiac tumors were operated upon in the Department of Cardiothoracic Surgery at the Postgraduate Institute of Medical Education and Research, Chandigarh. These included 34 (87%) patients with benign tumors and 5 (13%) patients with primary malignant tumors. All the benign tumors were myxomas, of which 31 (91.2%) were in the left atrium and 3 (8.8%) in right atrium. Primary malignant tumors comprised 2 rhabdomyosarcomas, 1 angiosarcoma, 1 lymphoma and 1 case of pleomorphic malignant fibrous histiocytoma. The diagnosis was established by echocardiography,

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Kocaman, Gökhan, Mustafa Bülent Yenigün, Burak Kaya, et al. "A rare giant sarcoma of the chest wall: Undifferentiated pleomorphic sarcoma." Turkish Journal of Thoracic and Cardiovascular Surgery 29, no. 4 (2021): 552–55. http://dx.doi.org/10.5606/tgkdc.dergisi.2021.20061.

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Undifferentiated pleomorphic sarcoma or, as formerly called, malignant fibrous histiocytoma is a type of sarcoma which originates from fibroblast and histiocytic cells. It is the most common type of sarcoma among all soft tissue sarcomas in adults. Its most common site is the lower limb, followed by the upper limb and the retroperitoneum. It is rarely encountered on chest wall. In the differential diagnosis of masses on chest wall, it is important to consider undifferentiated pleomorphic sarcoma in surgical planning. In this article, we report a male case with a giant undifferentiated pleomorp

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Black, Jennifer, Cheryl M. Coffin, and Louis P. Dehner. "Fibrohistiocytic Tumors and Related Neoplasms in Children and Adolescents." Pediatric and Developmental Pathology 15, no. 1_suppl (2012): 181–210. http://dx.doi.org/10.2350/11-03-1001-pb.1.

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Fibrohistiocytic tumors (FHTs) in children and adolescents range from the benign fibrous histiocytoma, or dermatofibroma, to a variety of intermediate and malignant neoplasms, such as dermatofibrosarcoma protruberans and high-grade undifferentiated pleomorphic sarcoma (malignant fibrous histiocytoma). Those tumors as a group are comprised of fibroblasts, myofibroblasts, and histiocytes-dendritic cells with a variably prominent inflammatory infiltrate consisting of lymphocytes and eosinophils. Dendritic cells are also a major constituent of another group of neoplasms that include Langerhans cel

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Goodlad, J. R., and C. D. M. Fletcher. "Malignant peripheral nerve sheath tumour with annulate lamellae mimicking pleomorphic malignant fibrous histiocytoma." Journal of Pathology 164, no. 1 (1991): 23–29. http://dx.doi.org/10.1002/path.1711640105.

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Kocak Uzel, Esengul, Metin Figen, Tuba Tulin Bek, Kubilay Inanc, Senem Onder, and Hazim orhan Kizilkaya. "Malignant Fibrous Histiocytoma of the Breast in Young Male Patient: A Case Report and a Review of the Literature." Case Reports in Oncological Medicine 2013 (2013): 1–4. http://dx.doi.org/10.1155/2013/524305.

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Malignant Fibrous Histiocytoma (MFH) is a fairly common tumor in the deep soft tissues: the most frequent primary sites are the lower (49%) and upper (19%) limbs, but it has been reported even in the retroperitoneum and abdomen (16%), while localization in the breast is extremely rare (1-2). Breast cancer is rarely seen in males, accounts for approximately 1% of all breast cancer, and the breast sarcomas constitute less than 1% of breast tumors in both sexes. In the review of the literature, this is the third male and first young male with MFH. Here, we present a 37-years-old male patient who

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Montgomery, E., and C. Fisher. "Myofibroblastic differentiation in malignant fibrous histiocytoma (pleomorphic myofibrosarcoma): a clinicopathological study." Histopathology 38, no. 6 (2001): 499–509. http://dx.doi.org/10.1046/j.1365-2559.2001.01152.x.

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Abbas, Rezhat, Suheel Hamid Latoo, Mohammad Shafi Dar, and Afreen Nadaf. "Undifferentiated pleomorphic sarcoma of maxilla." Saudi Journal of Oral Sciences 11, no. 2 (2024): 137–40. http://dx.doi.org/10.4103/sjoralsci.sjoralsci_29_24.

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Abstract Undifferentiated pleomorphic sarcoma (UPS) formerly known as malignant fibrous histiocytoma is a high-grade aggressive soft-tissue sarcoma. UPS is a soft-tissue sarcoma without a definable line of differentiation. Men between the ages of 50 and 70 are frequently affected by it. In adults, the lower extremity and retroperitoneum are the most affected sites, while the paranasal sinus is affected in younger individuals. A 16-year-old male patient reported with swelling in his left posterior maxilla for 2 months. The swelling began quickly and gradually expanded to its current size. On ex

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Schmitt, William R., Matthew L. Carlson, Caterina Giannini, Colin LW Driscoll, and Michael J. Link. "Radiation-Induced Sarcoma in a Large Vestibular Schwannoma Following Stereotactic Radiosurgery: Case Report." Neurosurgery 68, no. 3 (2011): E840—E846. http://dx.doi.org/10.1227/neu.0b013e31820780b1.

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AbstractBACKGROUND AND IMPORTANCE:Stereotactic radiosurgery (SRS) has been employed with increasing frequency in the treatment of benign intracranial tumors. While the risk for radiation-induced malignancy has been well studied for fractionated external beam radiation, reports of SRS-associated malignancy have only begun to emerge over the past 10 years.CLINICAL PRESENTATION:We present a case of a rapidly enlarging, presumed sporadic vestibular schwannoma in a 51-year-old man treated with SRS. Serial imaging over the next 7.5 years demonstrated good radiographic response with consistent involu

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Dr., Harsh Aggarwal, Vibhor Garg Dr., Sonika Lamba Dr., Shubham Gupta Dr., and Aneeshya CK Dr. "An Excellent Response to Chemotherapy in a Young Patient Diagnosed with Undifferentiated Pleomorphic Sarcoma: A Case Report and Review of Literature." International Journal of Innovative Science and Research Technology 8, no. 4 (2023): 1251–54. https://doi.org/10.5281/zenodo.7894400.

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Undifferentiated pleomorphic sarcoma (UPS) was earlier termed as malignant fibrous histiocytoma (MFH). UPH mainly affects extremities and retroperitoneum with the age predisposition of 50+. We present a case of 16 year old boy with malignant UPS; primary in thigh with lung metastases showing an excellent response to multidisciplinary approach involving surgeryfollowed by systemic combination chemotherapy. The treatment of the patient with metastatic UPS/MFH was successfulutilizing a multidisciplinary approach; although, this type of sarcoma carries a poor prognosis and seen to be insensitive t

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Ashmore, DL, and D. Dasgupta. "A splenic ‘cyst’: histology confirmed splenic sarcoma." Annals of The Royal College of Surgeons of England 102, no. 5 (2020): e105-e106. http://dx.doi.org/10.1308/rcsann.2020.0035.

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Primary malignant fibrous histiocytoma, now classified as pleomorphic undifferentiated sarcoma, is the most common soft-tissue sarcoma in adult life. Primary splenic pleomorphic undifferentiated sarcoma is extremely rare and aggressive, and is associated with a poor prognosis; only 14 cases of splenic pleomorphic undifferentiated sarcoma have been documented in the English literature. We discuss a case of a 56-year-old woman with iron-deficiency anaemia, early satiety and left upper-quadrant pain, who was preoperatively diagnosed with a large splenic cyst following thorough investigation. This

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Moradi, Arash, Abolfazl Afsharfard, and Khashayar Atqiaee. "Undifferentiated Pleomorphic Sarcoma Presenting as Abdominal Pain with a Pulsatile Mass." Case Reports in Surgery 2016 (2016): 1–3. http://dx.doi.org/10.1155/2016/8251043.

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Malignant fibrous histiocytoma (MFH) is a rare tumor that mostly involves adults aged 50 to 70. The most common anatomic location is the lower extremities. MFH of the retroperitoneum usually manifests late in its course and may be initially mistaken with other more common diagnosis. Here, the authors describe a 60-year-old man that was brought to the emergency department with a chief complaint of periumbilical abdominal pain. Our patient presented with symptoms consistent with a symptomatic aortic aneurysm, but a mass was encountered during surgery. In such circumstances the diagnosis of malig

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Ko, JS, HJ Kim, YM Choi, JW Kim, C. Park, and SH DO. "Diagnostic approach to malignant fibrous histiocytomas of soft tissue in dogs: a case report." Veterinární Medicína 58, No. 12 (2013): 621–27. http://dx.doi.org/10.17221/7181-vetmed.

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Malignant fibrous histiocytomas (MFHs), newly named as &lsquo;undifferentiated pleomorphic sarcomas&rsquo; in 2002 by the World Health Organization, generally show an ambiguous origin. They have been described to fibroblastic or histiocytic in origin, while storiform-pleomorphic variants share a similar morphologic pattern with other sarcomas. For this reason additional diagnostic methods including immunology, ultrastructure analysis and molecular approaches are necessary for a more accurate diagnosis. We report three cases of MFH in individual dogs which presented histological charact

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MUGAMBI, JW, RN CHEMWEY, and DK ONDIEKI. "Recurrent spindle cell sarcoma in pregnancy: a case report." Journal of Obstetrics and Gynaecology of Eastern and Central Africa 28, no. 2 (2016): 21–23. http://dx.doi.org/10.59692/jogeca.v28i2.342.

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Malignant Fibrous Histiocytoma (MFH) is a soft tissue sarcoma usually involving limbs and retroperitoneum. MFH of the anterior abdominal wall is rare with a high recurrence rate. Though wide surgical excision is the mainstay of treatment, it creates large abdominal wall defects that need reconstruction. The addition of chemotherapy and radiotherapy optimize the chances of survival and cure. We report a case of twice recurrent pleomorphic spindle cell sarcoma of the anterior abdominal wall in pregnancy, with adverse maternal and fetal outcome.

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CHOI, Hojung, Younghang KWON, Jinhwa CHANG, et al. "Undifferentiated Pleomorphic Sarcoma (Malignant Fibrous Histiocytoma) of the Head in a Dog." Journal of Veterinary Medical Science 73, no. 2 (2011): 235–39. http://dx.doi.org/10.1292/jvms.10-0183.

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Sugiura, Shimpei, Tomoyuki Tatenuma, Ryoko Sakata, et al. "MALIGNANT FIBROUS HISTIOCYTOMA/UNDIFFERENTIATED PLEOMORPHIC SARCOMA OF THE PENIS: A CASE REPORT." Japanese Journal of Urology 104, no. 6 (2013): 706–11. http://dx.doi.org/10.5980/jpnjurol.104.706.

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Inan, Haci Mehmet. "Storiform-Pleomorphic Type of Multifocal Malignant Fibrous Histiocytoma of the Lumbar Spine." American Journal of Case Reports 15 (2014): 565–68. http://dx.doi.org/10.12659/ajcr.891290.

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Vuity, Drazsen, Sandor Bogdan, Katalin Csurgay, Zoltan Sapi, and Zsolt Nemeth. "Malignant Fibrous Histiocytoma/Undifferentiated High-Grade Pleomorphic Sarcoma of the Maxillary Sinus." Pathology & Oncology Research 19, no. 4 (2013): 605–9. http://dx.doi.org/10.1007/s12253-013-9640-2.

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Idbaih, Ahmed, Jean-Michel Coindre, Josette Derré, et al. "Myxoid malignant fibrous histiocytoma and pleomorphic liposarcoma share very similar genomic imbalances." Laboratory Investigation 85, no. 2 (2004): 176–81. http://dx.doi.org/10.1038/labinvest.3700202.

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Siddiqui, Abdul Rehman, and Suha Mohammed Akbar. "A unique case of classic pleomorphic sarcoma restricted to the toes." International Surgery Journal 8, no. 8 (2021): 2488. http://dx.doi.org/10.18203/2349-2902.isj20213153.

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Over 50% of soft tissue sarcomas occurring in older adults are histologically pleomorphic and high grade. Most have traditionally been classified as malignant fibrous histiocytoma (MFH). MFH was originally defined as a malignant pleomorphic spindle cell neoplasm showing fibroblastic and histiocytic differentiation. More recently, pathologists have accepted that this morphology may be shared by a wide range of malignant neoplasms. Many sarcomas that were previously classified as pleomorphic MFH, on careful immunohistochemical and histopathologic analyses, revealed a specific line of differentia

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Paula, Carmen Déa Ribeiro de, Carolina Bezerra Benévolo Abbud, Luiz Eduardo de Almeida Prado Franceschi, et al. "Pleomorphic Dermal Sarcoma: a case report." Brazilian Journal of Case Reports 4, no. 1 (2023): 66–71. http://dx.doi.org/10.52600/2763-583x.bjcr.2024.4.1.66-71.

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This case report brings a 79-year-old man, with a history of melanoma in situ on the extensor part of the left arm, who presented with an ulcerated nodule on the scalp, right parietal region, with rapid and progressive growth for 3 months. The lesion was clinically compatible with squamous cell carcinoma, Merkel carcinoma, amelanotic melanoma and pleomorphic dermal sarcoma. Exeresis was performed and the diagnosis of Pleomorphic Dermal Sarcoma (PDS) was confirmed by histological and immunohistochemical evaluation. Pleomorphic Dermal Sarcoma (PDS), formerly known as malignant fibrous histiocyto

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DOI, Naotaka, Naoya MIKITA, Osamu MASUO, et al. "A case of malignant fibrous histiocytoma arising from frontal bone." Skin Cancer 28, no. 3 (2014): 315–19. http://dx.doi.org/10.5227/skincancer.28.315.

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Pedro, Duran1 Christian Edward Sánchez-Sánchez2 Eliezer Villanueva3 Citlaltepetl Salinas-Lara4 Carlos Sanchez-Garibay5 Martha Lilia Tena-Suck6*. "Clivus Undifferentiated Pleomorphic Sarcoma. A Case Report." International Clinical and Medical Case Reports Journal 3, no. 6 (2024): 1–13. https://doi.org/10.5281/zenodo.12562318.

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Undifferentiated pleomorphic sarcoma, previously called malignant fibrous histiocytoma, is a prevalent tumor, and it is usually associated with trauma and radiotherapy. They are found anywhere in the body, but those reported with localization at the skull base are very rare. The case of a 19-year-old girl who began with headache, vertigo, dysphagia to solids and liquids, and dysphonia, with a deviation of the tongue to the right, loss of balance to the right, and incontinence of urinary sphincters, is presented. A brain computed tomography was performed, which showed a lesion in the clivus wit

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