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Data publikacji: 4 czerwca 2021

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1

Pathak, Shantanu Chaturvedi. "Characterization of plasma-polymerized polyethylene glycol-like films." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/31789.

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Thesis (Ph.D)--Chemical Engineering, Georgia Institute of Technology, 2009.<br>Committee Chair: Dr. Dennis W. Hess; Committee Member: Dr. Clifford L. Henderson; Committee Member: Dr. J. Carson Meredith; Committee Member: Dr. L. Andrew Lyon; Committee Member: Dr. Mark R. Prausnitz. Part of the SMARTech Electronic Thesis and Dissertation Collection.

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Malik, Farooq. "Construction and characterisation of polyethylene glycol modified cytokines." Thesis, Open University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308154.

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Turner, Kelly A. "Polyethylene glycol stationary phases for capillary gas chromatography." Thesis, Virginia Tech, 1988. http://hdl.handle.net/10919/44090.

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The chromatographic properties of various silicone stationary phases for capillary gas chromatography have been extensively studied, yet the properties of nonsilicone phases have not been so well investigated. The most popular nonsilicone phases are the high molecular weight polyethylene glycols (HMW PEG) which are commercially available in a wide range of molecular weights, crossâ linkable and uncross-linkable (Carbowax 2OM and 4OM, the Superox series, etc.). Their most outstanding features are their unique polarity and selectivity; for this reason these phases are widely used in the analys

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Zuo, Amy. "Cross-interactions of bovine chymotrypsinogen-A and polyethylene glycol." Connect to resource, 2010. http://hdl.handle.net/1811/45411.

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Naigamwalla, Dinaz. "Effects of polyethylene glycol on colon carcinogenesis in rodents." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0005/MQ46132.pdf.

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COLLAZOS, STEPHANIE ORTIZ. "LANGMUIR FILMS OF FATTY ACID ESTERS OF POLYETHYLENE GLYCOL." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2015. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=29504@1.

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PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO<br>COORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIOR<br>CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO<br>PROGRAMA DE SUPORTE À PÓS-GRADUAÇÃO DE INSTS. DE ENSINO<br>Ésteres de polietilenoglicol derivados de ácidos graxos são surfactantes não iônicos biodegradáveis com aplicação em vários segmentos da indústria, em especial nas indústrias de óleo e gás, farmacêutica, de cosméticos e de alimentos. Ésteres de ácidos graxos naturais, tais como acido esteárico e palmítico, foram sintetizados e caracterizados, e os seus fil

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7

Houts, Frederick William. "Analysis of Methoxy-polyethylene Glycol-modified Human Serum Albumin." University of Toledo Health Science Campus / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=mco1149010508.

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Dancho, David M. "Analysis of Polyethylene Glycol in the α-Hemolysin Nanopore". VCU Scholars Compass, 2013. http://scholarscompass.vcu.edu/etd/483.

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Nanopores have been shown to be a useful analytical tool for single molecule detection. They have been used to study the composition of DNA and other molecules of interest. These pores are usually α-hemolysin which is a toxin from Staphylococcus aureus or more recently nanoscale synthetic solid state pores. Now we are beginning to look at other molecules or proteins by sending them into the nanopores and measuring a characteristic partial current blockade. In this thesis we look at polyethylene glycol (PEG) as it enters and blocks current through a single alpha hemolysin pore. We report the ef

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9

Howard, Matthew A. Neau Steven H. "The application of polyethylene oxide (PolyOx®) and methoxypolyethylene glycol (Carbowax Sentry®) in the production of extruded-spheronized beads with a high drug load." Diss., UMK access, 2004.

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Thesis (Ph. D.)--School of Pharmacy and Dept. of Chemistry. University of Missouri--Kansas City, 2004.<br>"A dissertation in pharmaceutical sciences and chemistry." Advisor: Steven H. Neau. Typescript. Vita. Description based on contents viewed Feb. 24, 2006; title from "catalog record" of the print edition. Includes bibliographical references (leaves 129-141). Online version of the print edition.

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Schmidt, Kurt A. G. "Solubility of sulphur dioxide in mixed polyethylene glycol dimethyl ethers." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/mq22670.pdf.

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Fu, Guopeng. "Molecular Complexation and Phase Diagrams of Urea/Polyethylene Glycol Mixtures." University of Akron / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=akron1366631616.

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Iza, Mustapha. "Caracterisations des proprietes interactionnelles, mecaniques et diffusionnelles d'hydrogels de polyethylene glycol." Paris 11, 1997. http://www.theses.fr/1997PA114853.

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Chatham, Sarah Marianna. "Characterisation of molten filled hard gelatin capsules." Thesis, King's College London (University of London), 1985. https://kclpure.kcl.ac.uk/portal/en/theses/characterisation-of-molten-filled-hard-gelatin-capsules(5b2e73bf-b02c-4ecc-b00a-146fd90ec814).html.

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Bayard, Fabrice J. C. "Increasing drug retention in lung tissue through conjugation with polyethylene-glycol." Thesis, University of Nottingham, 2013. http://eprints.nottingham.ac.uk/13214/.

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The pulmonary delivery of drugs is an attractive route of administration because of the large surface area and high permeability of the airway epithelium. The large majority of inhaled drugs are used to manage asthma and Chronic Obstructive Pulmonary Disorder (COPD), such as inhaled corticosteroids and β2-adrenergic receptor agonists. Local delivery of small molecules often results in sub-optimal pharmacokinetics characterised by short absorption times (tmax) and high systemic concentrations (Cmax). Numerous drug delivery strategies have been attempted to increase lung retention time, includin

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Ruttenberg, David. "Intestinal permeability to polyethylene glycol 400 in patients with Crohn's disease." Master's thesis, University of Cape Town, 1993. http://hdl.handle.net/11427/25587.

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An altered small intestinal permeability has been proposed as an important aetiological factor in the pathogenesis of inflammatory bowel disease. The relevant literature was reviewed. Intestinal permeability to Polyethylene glycol 400 in patients with Crohn' s disease, their relatives and healthy controls was examined and the data compared with studies of small bowel permeability to other similar sized probes. A new technique of analysis of urinary Polythylene Glycol 400 by High Performance Liquid Chromatography was described and compared with a previously established HPLC method. No evidence

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Qaderi, Kamran. "Polyethylene Glycol Diacrylate (PEGDA) Resin Development for 3D-Printed Microfluidic Devices." BYU ScholarsArchive, 2015. https://scholarsarchive.byu.edu/etd/5555.

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In this thesis, the successful fabrication of 3D-printed microfluidic devices will be discussed. Fabrication is performed with a low-cost commercially available stereolithographic 3D printer utilizing a custom PEGDA resin formulation tailored for low non-specific protein adsorption based on my colleagues' work [Rogers et al., Anal. Chem. 83, 6418 (2011)]. Horizontal microfluidic channels with designed rectangular cross sectional dimensions as small as 300 um wide and 150 um tall are printed with 100% yield, as are cylindrical vertical microfluidic channels with 300 um designed (334 um actual)

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Perney, Pascal. "Etude prospective de la tolérance et de l'efficacité de trois préparations pour la coloscopie." Montpellier 1, 1992. http://www.theses.fr/1992MON11064.

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Keskin, Tugba. "Preparation Of Polyethylene Glycol Coated Magnetic Nanoparticles For Targeting Of Cancer Cells." Master's thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12614089/index.pdf.

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Conventional cancer chemotherapies cannot differentiate between healthy and cancer cells, and lead to severe side effects and systemic toxicity. In the last decades, different kinds of controlled drug delivery systems have been developed to overcome these shortcomings of chemotherapeutics. Magnetic nanoparticles (MNP) are potentially important in cancer treatment since they can be targeted to tumor site by an externally applied magnetic field. In this study, it is aimed to synthesize folic acid conjugated<br>polyethylene glycol (PEG) coated magnetic nanoparticles with appropriate size, surfa

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19

Kinsley, Chris. "Soybean peroxidase-catalysed treatment of phenol in the presence of polyethylene glycol." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0001/MQ44018.pdf.

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Yeom, Sin Hea. "TEMPERATURE-DEPENDENT TUNABLE PHOTOLUMINESCENCE PROPERTIES OF CARBON NANODOTS DERIVED FROM POLYETHYLENE GLYCOL." UKnowledge, 2014. http://uknowledge.uky.edu/chemistry_etds/46.

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Fluorescent carbon dots (C-dots) are well known for their low cell-cytotoxicity, biocompatibility, low preparation cost, excitation dependent photoluminescence, and excellent photostability. Typically, raw C-dots have low quantum efficiency and thus researchers have been utilizing biocompatible polymers such as polyethylene glycol (PEG) as a passivation agent in order to increase fluorescence signal. In this work, we report fluorescent self-passivated carbon nanodots (CNDs) synthesized from PEG by using it as a carbon source as well as a passivating agent. Importantly, the addition of graphene

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Gustafsson, Carla Astrid. "Modified polyethylene glycol hydrogels for growth factor delivery and controlled tissue invasion." Master's thesis, Faculty of Health Sciences, 2019. http://hdl.handle.net/11427/31068.

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The prevalence of cardiovascular disease and myocardial infarction-induced heart failure has risen significantly over recent years, emphasising the need for new, effective therapeutic strategies. A promising alternative approach is the cardiac delivery of potentially cardioprotective and regenerative growth factors from biomaterial scaffolds. One hydrogel system that has promise in this area is an injectable enzymatically degradable polyethylene glycol (PEG) hydrogel. Two modifications aimed at further optimising this system as a regenerative medicine scaffold were explored. Firstly, the coval

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Muenyi, Clarisse Sornsay. "Cell Toxicology Study of RRR-Alpha-Tocopheryl Polyethylene Glycol 1000 Succinate (TPGS)." Digital Commons @ East Tennessee State University, 2005. https://dc.etsu.edu/etd/1037.

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This research focused on the cytotoxic properties of RRR-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS) in transformed and cancerous cell lines. We used RAW264.7 macrophage and prostate cancer (LNCaP) cell lines in this study. TPGS caused cell death and decreased cell viability in a dose and time dependent manner. Cell death was evaluated fluorimetrically by employing the nucleic acid-binding fluorophore; propidium iodide. A colorimetric 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide (MTT) assay was used to evaluate cell viability. Cell death can occur through necr

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Balasubramanian, Shankar Ganesh Sokkalinga Simonian Aleksandr L. "Development of smart functional surfaces for biosensor applications." Auburn, Ala, 2008. http://repo.lib.auburn.edu/EtdRoot/2008/FALL/Materials_Engineering/Dissertation/Balasubramania_S%20G_2.pdf.

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Thesis (Ph. D.)--Auburn University, 2008.<br>Abstract. Vita. The following patent resulted from the dissertation research: Davis, V., Simonian, A.L., Nepal, D., Balasubramanian, S, "Preparation of Precisely Controlled Thin Film Nanocomposites of Carbon Nanotubes and Biomaterials", U.S. Provisional Patent Application No. 61/000,938, filed on 30 October 2007. The following peer-reviewed publications resulted from the dissertation research: Dhriti Nepal, Shankar Balasubramanian, Aleksandr Simonian, and Virginia Davis, "Mechanically Strong Antibacterial Thin Film Based on Single-Walled Carbon Nano

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Samkange, Tendai. "Evaluation of the effect of polyethylene glycol incorporation on the performance of poly(lactic-co-glycolic acid) nanoparticles." University of the Western Cape, 2016. http://hdl.handle.net/11394/6112.

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Magister Scientiae - MSc (Pharmaceutical Chemistry)<br>Nanoparticle drug delivery is challenged by the binding of proteins in blood which result in their rapid removal from the circulatory system. Nanoparticles engineered to delay protein binding have shown to have extended circulatory times. One such engineering technique is PEGylation, which is the coating of nanoparticles with polyethylene glycol (PEG). PEG shields the nanoparticle from adhesive interactions with proteins. However, the optimal PEG content required to impart this "stealth" property onto poly(lactic-co-glycolic acid) (PLGA) n

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Calmeyn, Timothy J. "Optimization of the melt-phase polyethylene terephthalate manufacturing process." Ohio : Ohio University, 1995. http://www.ohiolink.edu/etd/view.cgi?ohiou1179336415.

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Bejaoui, Mohamed. "Polyethylene glycol conditioning: An effective strategy to protect against liver ischemia reperfusion injury." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/385612.

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Ischemia is defined by the arrest of blood flow in the organ cutting thus oxygen and metabolite supply indispensable for its survival and function. Restoration of blood flow in hypoxic tissue, called reperfusion, can paradoxically result in more destructive than beneficial effects. Ischemia reperfusion injury (IRI) is an inevitable problem in many clinical situation of liver surgery such as organ transplantation, trauma and liver resection. Therapeutic strategies against IRI have been developed during the last 60 years and great advance into the mechanisms responsible of injuries have been ach

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Scally, David James. "Novel polyethylene glycol based drug delivery systems : a calorimetric and QASAR based study." Thesis, University of Kent, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282425.

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Allehyani, S. H. A., R. Seoudi, D. A. Said, A. R. Lashin, and A. Abouelsayed. "Synthesis, Characterization, and Size Control of Zinc Sulfide Nanoparticles Capped by Polyethylene Glycol." Thesis, Sumy State University, 2015. http://essuir.sumdu.edu.ua/handle/123456789/42490.

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Zinc sulfide nanoparticles were synthesized with controllable size via chemical precipitation. highresolution transmission electron microscopy (HRTEM) and X-ray powder diffraction (XRD) showed that the samples were grown with the cubic phase; the particle size was varied by varying the molar ratios of zinc chloride and sodium sulfide in the presence of poly(ethylene glycol). The optical band gap was calculated on the basis of ultraviolet-visible spectroscopy (UV-VIS) and ranged from 4.13 eV to 4.31 eV depending on the particle size. Surface passivation and adsorption of poly(ethylene glycol) o

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Ralph, J. "Chemical treatment of backsawn Tasmanian Oak with Polyethylene Glycol (PEG) prior to drying." Thesis, University of Tasmania Library, Special & Rare Materials Collections, 2006. https://eprints.utas.edu.au/1222/1/JRalphthesis_front.pdf.

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A series of experiments was conducted with the view of obtaining baseline information on the use of polyethylene glycol (PEG) on Tasmanian Oak for the purpose of improving the quality of the seasoned structural timber product. Tasmanian Oak is the marketing name for a triad of Tasmanian-grown eucalypt species (E. delegatensis, E. obliqua, and E. regnans). Incubation of freshly-milled timber in aqueous PEG solutions prior to seasoning follows on from investigations in northern hemispheric timber species such as hoop pine and spruce in the middle of the 20th Century. PEG penetrates freshly sawn

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Dumetz, André C. "Measurement of protein-protein interactions applied to protein crystallization in salt and polyethylene glycol solutions." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file 1.40Mb., 130 p, 2005. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:1428182.

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Perrier, SeÌbastien. "Synthesis of novel surface active agents via copper mediated living radical polymerisation : synthetic and mechanistic study." Thesis, University of Warwick, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246763.

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Daugherty, Megen Aileen. "The Safety and Efficacy of Oral Low-Volume Sodium Phosphate Bowel Preparation for Colonoscopy in Dogs." Thesis, Virginia Tech, 2006. http://hdl.handle.net/10919/34080.

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Sodium phosphate (NaP) is a low-volume, hyperosmolar laxative that has been shown to be an effective bowel cleansing agent in people. The purposes of this study were to evaluate the safety and efficacy of oral NaP in dogs. Standard (NaP and enemas; NaP1) and control preparations (polyethylene glycol [PEG] and enemas) were compared in a crossover design to determine safety and efficacy of NaP. Serial clinical and serum analytical evaluations were used to determine the safety of NaP. The efficacy of the NaP1 preparation was compared to 3 NaP variations which excluded enema or included bisacodyl

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Farbod, Kambiz. "Uv and spontaneously cured polyethylene glycol-based hydrogels for soft and hard tissue scaffolds." Thesis, KTH, Skolan för kemivetenskap (CHE), 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-32940.

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UV-curing is one of the most commonly used methods for producing hydrogels for soft and hard tissue scaffolds. Spontaneous curing is an alternative method which possesses some advantages in comparison to the conventional UV-curing methods; for example, in situ crosslinking and excluding initiators. The main objective of this study was to investigate promising materials for producing UV and spontaneously cured hydrogels, and subsequently to perform a comparison between the produced hydrogels with regard to their different mechanical and physical properties.Seventeen different hydrogels includin

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Codoni, D. "Development and physical characterisation of polyethylene glycol glycerides-based gel formulations for macromolecule delivery." Thesis, University of East Anglia, 2013. https://ueaeprints.uea.ac.uk/48764/.

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Lipid-based delivery systems offer many advantages on enhancing the bioavailability of protein/peptides. Gelucire 50/13 is a complex mixture of glycerides and PEG. It is mainly used in solid oral formulations for delivering small molecular weight drugs. The purpose of this project was to develop novel uses of Gelucire as a liquid crystalline-based gel-forming material for protein/peptide delivery. A thorough physical and mechanical characterisation of the gels (with and without lysozyme as a model protein) was conducted using a combination of analytical techniques including ATR-FTIR, DSC, rela

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Aljaeid, Bader Mubarak. "Formulation of novel cross-linked sterically stabilised polyplexes with polyethylene glycol for DNA delivery." Thesis, University of Nottingham, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.588065.

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Linear poly(amidoamine) (PAA) cationic polymers complexed with DNA have potential as non-viral nucleic acid delivery systems. However, they have poor in vivo biodistribution and a tendency to aggregate. PEGylation polymers are a potential solution for these problems but previous work shows that they do not always form compact complexes. This might be overcome by using mixtures of homopolymer and PEGylated copolymer to form complexes. However, the complexes are unstable in the presence of serum. Therefore, the aim of this study was to improve stability and to allow release of DNA by incorporati

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Gunbas, Ismail Dogan. "Preparation And Characterization Of Chitosanpolyethylene Glycol Microspheres And Films For Biomedical Applications." Master's thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/2/12608817/index.pdf.

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In recent years, biodegradable polymeric systems have gained importance for design of surgical devices, artificial organs, drug delivery systems with different routes of administration, carriers of immobilized enzymes and cells, biosensors, ocular inserts, and materials for orthopedic applications. Polysaccharide-based polymers represent a major class of biomaterials, which includes agarose, alginate, dextran, and chitosan. Chitosan has found many biomedical applications, including tissue engineering, owing to its biocompatibility, low toxicity, and degradation in the body, which has opened up

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Bali, Sinazo. "Polyethylene glycol (PEG) induced water stress alters the physiological and molecular responses of chia plants." The University of the Western Cape, 2017. http://hdl.handle.net/11394/5787.

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Magister Scientiae - MSc (Biotechnology)<br>Water deficit is known to be one of the most detrimental environmental factors to affect crop production and growth in South Africa. This factor has become more apparent with increasing cases of drought in the country.

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Tuesca, Anthony D. Lowman Anthony M. "Synthesis, characterization, and application of polyethylene glycol modified insulin for oral delivery using complexation hydrogels /." Philadelphia, Pa. : Drexel University, 2008. http://hdl.handle.net/1860/2715.

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Dalton, Dustin. "Assessing the Role of Polyethylene Glycol (PEG) in Improving Functional Recovery Following Spinal Cord Injury." VCU Scholars Compass, 2011. http://scholarscompass.vcu.edu/etd/2543.

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Injury to the spinal cord results in the disruption of signal transmission between the brain and distal targets. It often presents with the loss of motor function and sensory perception below the level of injury. There are many obstacles following injury that must be overcome in order to encourage axon regeneration and improve functional recovery. A combinatorial approach is necessary to combat physical and chemical barriers to recovery. The fluid filled cyst that forms in the majority of spinal cord injuries presents a physical barrier that we treat with our electrospun bridges. We impla

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Requardt, Hendrik [Verfasser]. "Polyethylene Glycol functionalized Multi Walled Carbon Nanotubes for Nanomedical application as Drug Carriers / Hendrik Requardt." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2017. http://d-nb.info/115034105X/34.

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Rogers, Chad. "Optimization of Nonadsorptive Polymerized Polyethylene Glycol Diacrylate as a Material for Microfluidics and Sensor Integration." BYU ScholarsArchive, 2015. https://scholarsarchive.byu.edu/etd/5310.

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Microfluidics is a continually growing field covering a wide range of applications, such as cellular analysis, biomarker quantification, and drug discovery; but in spite of this, the field of microfluidics remains predominately academic. New materials are pivotal in providing tailored properties to improve device integration and decrease prototype turnaround times. In biosensing, nonspecific adsorption in microfluidic systems can deplete target molecules in solution and prevent analytes, especially those at low concentrations, from reaching the detector. Polyethylene glycol diacrylate (PEGDA)

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Fishman, Alexander. "Synthesis, characterization and applications of novel polyethylene glycols in organic chemistry /." 2004. http://wwwlib.umi.com/cr/yorku/fullcit?pNQ99168.

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Thesis (Ph.D.)--York University, 2004. Graduate Programme in Chemistry.<br>Typescript. Includes bibliographical references (leaves 160-172). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://wwwlib.umi.com/cr/yorku/fullcit?pNQ99168

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Chao, Yin-chun, and 趙尹淳. "Synthesis and Application of polyethylene glycol Copolymers." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/94875719877313156470.

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博士<br>國立臺灣科技大學<br>材料科學與工程系<br>100<br>In this study, a series of polyethylene glycol copolymers were prepared by the reaction of combining polyethylene glycol (PEG), Vinyltriethoxy silane (VTES) and N-Vinylpyrrolidone (NVP). One of these polyethylene glycol copolymers is PEG/VTES copolymers, and the other is PEG/PVP copolymers. PEG/VTES copolymers exhibited excellent surface activities, wetting power, as well as low foaming. Consequently, the application of a series of PEG/VTES copolymers can make cotton fabrics stain-resistant. PEG/PVP copolymers are products of biodegradable material polymeri

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Munoz, Pinto Dany 1981. "Hybrid Polyethylene Glycol Hydrogels for Tissue Engineering Applications." Thesis, 2011. http://hdl.handle.net/1969.1/149213.

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Currently, organ transplant procedures are insufficient to address the needs of the number of patients that suffer of organ failure related disease. In the United States alone, only around 19% of the patients are able to get an organ transplant surgery and 25% die while waiting for a suitable donor. Tissue engineering (TE) has emerged as an alternative to organ transplant; thus, the aim of the present study was to validate a poly(ethylene glycol) diacrylate (PEG-DA) hydrogel system as a model for material scaffolding in TE applications. This work explores the influence of scaffold material pro

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Hsiao, Sheng-Wen, and 蕭勝文. "Generation and cloning of anti-polyethylene glycol antibody." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/72993943881333776458.

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碩士<br>高雄醫學大學<br>醫學研究所碩士班<br>93<br>The covalent bond the polyethylene glycol (polyethylene glycol, PEG) to protein improves its safety and the efficacy. PEG is one kind of water-solubility polymer. The matters after PEG modification for example: protein, hormone, and enzyme and cause to change the water solubility, reduces immunogenicity, increase the half-life, and change biodistribution. PEG modification drugs at present already had PEG-Intron (PEG-interferon alpha 2b), pegasys (PEG-IFN alpha 2a), PEG-Neupogen (PEG-G-CSF) and PEGV isomant (PEG-hGHra)that have been approved by the food and

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Chen, Ting-Yu, and 陳挺宇. "The biomedical applications of anti-polyethylene glycol antibody." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/96055352430359384535.

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碩士<br>高雄醫學大學<br>醫學檢驗生物技術學研究所<br>99<br>PEGylation of protein drugs are increasingly popular for improving clinical pharmacokinetics. However, quantification of PEGylated proteins with protein-specific sandwich enzyme-linked immunosorbent assay (ELISA) is not sensitivity due to the shielding effect of PEG that prevents the binding of protein-specific antibody. To overcome this problem, an optimized anti-PEG sandwich ELISA developed with anti-PEG antibodies (AGP4 and biotinylated 3.3) was used to measure PEGylated protein drugs as well as PEG (12kDa)–interferon α-2b (PEG-IntronR) and PEG (40kDa)–

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CHOU, joyce, and 周俊利. "Polystyrene-(Polyethylene glycol) block copolymer,synthesize and structure identification." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/97856856302162136078.

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碩士<br>國立成功大學<br>化學工程學系<br>86<br>Abstract We attempted to synthesize a series block copolymers of Polystyrene-(Polyethylene glycol) by two methods：One is iniferter system and the other is macroazoinitiator system. Block copolymers involved different PEG''s molecular weights ,600、2000、4000, in the polymer chains. The prepared polymers thus contained 34∼89 wt% of PS hard segments obtaining from elemental analysis (EA). Gel permeation chromatography (GPC) was used to determine th

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Francisco, Aubrey Therese. "Laminin-Functionalized Polyethylene Glycol Hydrogels for Nucleus Pulposus Regeneration." Diss., 2013. http://hdl.handle.net/10161/8204.

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<p>Intervertebral disc (IVD) disorders and age-related degeneration are believed to contribute to low back pain. There is significant interest in cell-based strategies for regenerating the nucleus pulposus (NP) region of the disc; however, few scaffolds have been evaluated for their ability to promote or maintain an immature NP cell phenotype. Additionally, while cell delivery to the pathological IVD has significant therapeutic potential for enhancing NP regeneration, the development of injectable biomaterials that retain delivered cells, promote cell survival, and maintain or promote an NP

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Yang, Hsiang-yun, and 楊翔雲. "Synthesis and Optimization of Sulfated Monooleate Polyethylene Glycol Polyester." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/93vu35.

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碩士<br>國立臺北科技大學<br>有機高分子研究所<br>105<br>Sulfated monooleate polyethylene glycol polyester is an anionic surfactant, which can be produced by the reaction of monooleate polyethylene glycol (PEG300MO) with sulfamic acid. The sulfation efficiency is usually influenced by the water content of PEG300MO, as well as the mole ratio of reactants. Theoretically, the lower the water content and the higher the sulfamic acid, the better the sulfation efficiency. However, it takes a lot of energy and time to obtain low-moisture PEG300MO in an industrial scale. Using a high proportion of sulfamic acid also incr

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Jebrail, Mais J. "Effect of aliphatic chain length on the stability of poly(ethylene glycol)-grafted phospholipid mixed monolayers at the air/water interface /." 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:MR32003.

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Thesis (M.Sc.)--York University, 2007. Graduate Programme in Chemistry.<br>Typescript. Includes bibliographical references. Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:MR32003

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