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1

Mohammed, Raghad H., and Asmma E. Al Niaame. "Evaluation of the Biological Efficacy and Physicochemical Evaluation of Toothpaste Prepared from Few Types of Plant Extracts against Some Pathogenic Bacteria Isolated from the Mouth." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 12, no. 04 (2022): 1626–31. http://dx.doi.org/10.25258/ijddt.12.4.25.

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The demand for a herbal-based products such as toothpaste is high these days. Consumers believed that herbal-based toothpaste are safe, effective and less toxic because few and safe chemicals is used as compared to synthetically produced toothpaste. Therefore, this study was amied to formulate and evaluate new polyherbal toothpaste containing herbal extracts available to treat periodontal problems. The polyherbal toothpaste was formulated using three herbal extracts namely lemongrass (Cymbopogon citratus L.) marjoram (Qriganum majorana L.) and salivia (Salvia officinalis L.) and tested against
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Shukla, Kavita Varma, and Deepika Kumari. "Formulation Development and Evaluation of Herbal Toothpaste for Treatment of Oral Disease." Journal of Drug Delivery and Therapeutics 9, no. 4-s (2019): 98–104. http://dx.doi.org/10.22270/jddt.v9i4-s.3344.

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Streptococcus mutans is the most common cause of tooth decay. Parabens and other commonly used as anti-Streptococcus agents in toothpaste industry have numerous side effects such as discoloration of teeth. The herbal extract of all three plants gives antimicrobial and anti-inflammatory activity and prevent and reducing the tooth decay, dental caries and given to freshness of mouth. The aim of present work was development and evaluation of herbal antimicrobial toothpaste containing Bark of Acacia nilotica, Acacia catechu and flower buds of syzygium aromaticum as herbal ingredients. Different ty
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AD Burande, AS Zadokar, AM Deshmukh, et al. "Review on herbal drug used in various dental problems." International Journal of Science and Research Archive 13, no. 2 (2024): 411–23. http://dx.doi.org/10.30574/ijsra.2024.13.2.2071.

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Polyherbal tooth paste is gaining recognition as an organic a substitute for conventional oral care utilizing the advantages of various herb constituents for elevated oral hygiene this review looks at the contents evaluation and antibacterial properties of polyherbal toothpaste with a focus on key components of medicinal value such clove tulsi neem and aloe vera we discuss formulation techniques and their effects on stability and effectiveness as well as assessment instruments to measure physical and microbiological characteristics in vitro tests show that polyherbal toothpaste is effective ag
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Sharanya, R. K. 1. Fathimath Fitha M. A.2* Anisa A.2 Muhammed Sahadath K.2 Sameena P. L. 2. Thanveera Kunheeritheeri2. "Formulation And Evaluation Of Polyherbal Toothpaste." International Journal in Pharmaceutical Sciences 2, no. 9 (2024): 1333–40. https://doi.org/10.5281/zenodo.13850938.

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Toothpaste is a gel or paste formulation product and is used to clean and maintain oral hygiene with the aid of toothbrush. The majority of the cleaning is performed by the mechanical utilisation of the toothbrush with the help of excipients used in toothpaste. The aim of this investigation is to evaluate herbal toothpaste formulation. Herbal toothpaste with natural ingredients is more acceptable in public opinion than chemical-based formulation due to their safety and efficacy in reducing dental caries and preventing other dental disorders. The objective of the present research work is to for
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Daburkar, karishma. "Formulation and Evaluation of Polyherbal Psidium Guajava Toothpaste(Guava leaves)." INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 09, no. 06 (2025): 1–9. https://doi.org/10.55041/ijsrem50741.

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In this study, a toothpaste formulation that is entirely herbal is made. There is a high demand for herbal products these days for the treatment and curing of oral hygiene. Many people have a variety of oral and dental health issues. There are many diseases and disorders related to teeth, and in order to treat them, dentists prescribe a variety of medications and treatments, some of which are painful and uncomfortable. In fact, for oral and dental hygiene, we use a variety of synthetic toothpastes made with chemical combinations, which can have severe side effects and toxicity. As a result, co
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6

Sanika Manoj Karale, Kashish Shabbir Patel, Priti Dnyandev Gadge, Ajinkya Tukaram Darade, Prachi N. Padwal, and Shubham Chandrakant Gadge. "Polyherbal dentifrice: A review of literature." World Journal of Biology Pharmacy and Health Sciences 20, no. 3 (2024): 162–68. https://doi.org/10.30574/wjbphs.2024.20.3.0997.

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Overall well-being depends on one's oral health. It impacts not just our general health but also our capacity to eat; speak; and smile with assurance. Numerous systemic disorders; Poor oral health has been linked to conditions including diabetes; heart disease; and respiratory infections. Toothpaste is essential for preserving dental health. Plaque and germs are eliminated; cavities are avoided; foul breath is lessened; and gum disease is avoided. Certain toothpastes have components that can help whiten teeth and get rid of surface stains. Growing knowledge of natural components: People are lo
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Khandgaonkar, Madhuri, Bhagyashri Gayke, and Anjali Shinde. "Formulation and Evaluation of Polyherbal Toothpaste: To Overcome Oral Problems." International Journal for Research in Applied Science and Engineering Technology 11, no. 7 (2023): 1291–306. http://dx.doi.org/10.22214/ijraset.2023.54838.

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Abstract: Polyherbal toothpaste with natural ingredients is more acceptable in public opinion than chemical-based synthetic formulations in the current oral dental care scenario due to their safety and efficacy in reducing dental caries and preventing other dental disorders to which this generation is prone. In this composition, we use, clove, Neem, pomegranate peel , all of which have never been used before in any research. These extracts have anti-ulcer, anti-caries, anti-bacterial, and remedial properties, as well as certain unique properties including anti-cancer and anti-fungal. Herbal to
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8

Nayak, Sachin, Kirankumar GD, Vikesh ., Pradyumna B, and Sandeshraj . "FORMULATION AND EVALUATION OF HERBAL TOOTHPASTE." Journal of Biological & Scientific Opinion 12, no. 5 (2024): 54–59. http://dx.doi.org/10.7897/2321-6328.12598.

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The present study is concerned with the formulation and evaluation of herbal toothpaste, which contains various properties like tooth abrasives, tooth whitening, anti-caring, antibacterial, anti-inflammatory, desensitivity, etc. The herbal toothpaste was prepared using mango leaf extract and guava leaf extract as active ingredients, along with various excipients, which include calcium carbonate, sodium chloride, sodium lauryl sulphate, sodium benzoate, glycerine, camphor, honey and distilled water. The toothpaste was prepared by homogeneous mixing of all the excipients and the herbal extract.
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9

Anshul, Burande* Adesh Nikam Abhishek Deshmukh Akash Avachar Abhay Zadokar Dr. A. D. Gattani Dr. R. H. Kale. "Formulation and Evaluation of Novel Polyherbal Toothpaste." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 1782–94. https://doi.org/10.5281/zenodo.15383674.

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The present investigation aimed to design and assess a novel polyherbal toothpaste formulated as a natural and effective option for oral hygiene. The goal was to integrate various plant-based extracts known for their antimicrobial and anti-inflammatory effects to support dental health and prevent oral infections. Medicinal herbs including Azadirachta indica (neem), Syzygium aromaticum (clove), Acacia nilotica (babool), and Emblica officinalis (amla) were selected based on traditional medicinal practices and their established therapeutic potential. The formulation was prepared using the tritura
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10

Supid, Khanal1 Arjun Bhandari2. "Formulation And Physiochemical Evaluation Of Polyherbal Toothpaste Using Domestic Medicinal Plants." International Journal in Pharmaceutical Sciences 2, no. 7 (2024): 962–75. https://doi.org/10.5281/zenodo.12738905.

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This study aimed to formulation and evaluation of poly herbal toothpaste using domestic medicinal plants were collected from Butwal Sub-Metropolitan City, Nepal processed and shed dried followed by cold maceration by using distilled water. Herbal Formulation toothpaste (F1) and (F2) were prepared by using herbal extract neem, turmeric, betel, peppermint, guava and other ingredient calcium carbonate, sodium lauryl sulphate, glycerin, gum, saccharin and other preservative. The formulated herbal toothpaste is compared with marketed toothpaste they give beneficial action and safety. The observatio
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11

Narayanasamy, Anuradha S., Sharmila, Nivetha, VithyaSri, and Archana. "Formulation and Evaluation of Poly Herbal Tooth Paste." Journal of Pharmaceutical Research International 35, no. 19 (2023): 13–18. http://dx.doi.org/10.9734/jpri/2023/v35i197396.

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Oral hygiene can be maintained throughout the day by using various dentifrices prepared with herbal and synthetic ingredients. Oral hygiene is maintained to keep the mouth fresh and avoid tooth decay. The largest producer of healthful herbs is India which is known as the botanical garden of the world. The main aim of this work is to formulate and evaluate polyherbal toothpaste and compare it with marketed products of the same category. The toothpaste was prepared by using several herbal ingredients which show antibacterial, antiseptic, and cooling properties. Neem, clove, babool, banyan, amla,
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12

Mohire, NitinC, and AdhikraoV Yadav. "Chitosan-based polyherbal toothpaste: As novel oral hygiene product." Indian Journal of Dental Research 21, no. 3 (2010): 380. http://dx.doi.org/10.4103/0970-9290.70808.

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13

Pratiksha Chaudhari, Pratiksha Chaudhari, Soniya Bije Soniya Bije, Krishna Bhosle Krishna Bhosle, Karan Chavan Karan Chavan, Vaibhav Bhute Vaibhav Bhute, and Ms P. A. Bhosle Ms. P. A. Bhosle. "Formulation and Evaluation of Herbal Toothpaste Using Polyherbal Plants." International Journal of Pharmaceutical Research and Applications 10, no. 2 (2025): 1863–77. https://doi.org/10.35629/4494-100218631877.

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14

Dinnimath, BasavarajM, and S. Abhay. "Formulation and evalution of new polyherbal toothpaste for oral care." Indian Journal of Health Sciences 8, no. 1 (2015): 24. http://dx.doi.org/10.4103/2349-5006.158217.

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15

Jatin Rajendra Kudnar, Swapnil Sanjay Mirajgave, Nandini Vitthal Kumavat, and Gurudeo Shivaji Mandhare. "Natural oral care: Formulation and evaluation of a polyherbal toothpaste." International Journal of Science and Research Archive 14, no. 3 (2025): 496–503. https://doi.org/10.30574/ijsra.2025.14.3.0675.

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Herbal formulations are increasingly preferred over synthetic alternatives due to their natural origin and minimal side effects. This study aims to develop a safe and effective polyherbal toothpaste using Shikakai (Acacia concinna) extract as a natural foaming agent, replacing synthetic surfactants like Sodium Isethionate. The formulation incorporates Neem (Azadirachta indica), Clove (Syzygium aromaticum), Turmeric (Curcuma longa, API: Curcumin), and Aloe Vera (Aloe barbadensis), which offer multiple medicinal benefits such as reducing dental plaque, gingivitis, cavities, gum diseases, and mou
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16

Ch., Srilatha, Jayasri Golla, Sreeja M., Satyanarayana NY., and Mamatha Kola. "Evaluation of Anti-inflammatory and Anti-Bacterial Effects of Polyherbal Toothpaste with Neem, Fenugreek and Pomegranate Peel Extract." Asian Journal of Research in Pharmaceutical Sciences, April 22, 2025, 129–34. https://doi.org/10.52711/2231-5659.2025.00020.

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Objective: To Formulate and evaluate polyherbal toothpaste with neem, fenugreek, pomegranate peel extracts, for anti-inflammatory and anti-bacterial effects. Method: Extract of polyherbal formulations were prepared using methanol. Standard cultures of staphylococcus aureus and candida albicans, gram positive were used for the study. The antibacterial test used was the agar well diffusion method. Anti-inflammatory effect of polyherbal toothpaste was determined by protein denaturation method. Also evaluation parameters like foamability, spreadability, pH and other tests were performed and are co
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17

Sadeghi-Nejad, Batool, Eskandar Moghimipour, Sedigheh Yusef Naanaie, and Shahrzad Nezarat. "Antifungal and antibacterial activities of polyherbal toothpaste against oral pathogens, In vitro." Current Medical Mycology 4, no. 2 (2018). http://dx.doi.org/10.18502/cmm.4.2.65.

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 Original article
 Article History:
 Received: 23 April 2018 Revised: 20 July 2018 Accepted: 06 August 2018
 * Corresponding author:Batool Sadeghi-NejadAbadan School of Medical Sciences, Abadan, Iran.Email: batsad4@yahoo.com
 Introduction
 One of the most common chronic oral infections in the world is dental caries [1]. Oral pathogenic microorganisms have been the cause of dental plaques, dental caries, as well as gingival and periodontal diseases [2]. Streptococcus mutans is one of the main opportunistic pathogens of dental caries, which is respons
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18

Kaspate Shubham, Kamble Esha, and Kharabe Khushi. "Review on Formulation of Polyherbal Toothpaste Using Medicinal Plants." International Journal of Scientific Research in Science and Technology, January 1, 2024, 47–54. http://dx.doi.org/10.32628/ijsrst52310661.

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Toothpaste is a gel or paste formulation product and is use to clean and maintain oral hygiene with the aid of toothbrush. But some of these substances show undesirable side effects such as tooth staining and altered taste. India is that the largest producer of healthful herbs and is termed the “Botanical Garden of the world”. The objective of the present review to formulate herbal toothpaste containing natural ingredients like clove fruit, Neem leaves, Honey and Acacia powder, Betel, Peppermint, Turmeric, Guava etc. which were traditionally used for tooth cleaning. They not only show antimicr
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19

A. Shingte, Bhagyashree, Shronavi M. Pawar, Paurnima R. Chavan, and Kajal B. Malave. "Formulation and Evaluation of Poly Herbal Toothpaste." International Journal of Innovative Science and Research Technology (IJISRT), September 20, 2024, 517–28. http://dx.doi.org/10.38124/ijisrt/ijisrt24sep090.

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Herbal toothpaste formulations have gained significant attention due to their potential therapeutic benefits and natural origins. This study aims to prepare and evaluate a polyherbal toothpaste incorporating extracts of ginger, lemon, liquorice, and amla. Wet gum method is one process used to create a herbal toothpaste. Evaluation parameters included physical characteristics like colour, texture, pH, and functional properties like antimicrobial activity, spreadability, foaming property, homogeneity, abrasiveness, whitening effect. Results demonstrated that the herbal toothpaste exhibited desir
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20

Abhay, S., B. M. Dinnimath, and K. K. Hullatti. "FORMULATION AND SPECTRAL ANALYSIS OF NEW POLYHERBAL TOOTHPASTE." Journal of Drug Delivery and Therapeutics 4, no. 6 (2014). http://dx.doi.org/10.22270/jddt.v4i6.1011.

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Parande, Bhagyashree, S. D. More, C. C. Dongaonkar, et al. "Formulation and Evaluation of Dentifrice containing Sesbania grandiflora with Natural Elements." Research Journal of Topical and Cosmetic Sciences, December 28, 2024, 70–74. https://doi.org/10.52711/2321-5844.2024.00012.

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Toothpaste is a gel – or paste-based formulation product that is used to clean and maintain oral hygiene with the aid of a toothbrush. The research aims to formulate and evaluate an herbal toothpaste containing Sesbania grandiflora (hadga) flower, which has an antiplaque activity. The Sesbania grandiflora is a locally available natural herb that is not yet used in any toothpaste formulation. Various chemicals and preventive agents have beneficial effects or prevent oral disease. But some of these will have undesirable side effects such as dental staining, altered taste other health-related iss
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Matangi, Surya Prabha, Ramu Samineni, Kanhaiya Kumar, Ashutosh Kumar, Shantanu Kumar, and M. Salmon Raju. "Plants as Regular Phytochemical Sources of Dentistry - Formulation and Evaluation of Polyherbal Tooth Paste." Journal of Natural Remedies, February 1, 2024, 397–407. http://dx.doi.org/10.18311/jnr/2024/34575.

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Different plant components have been used in medicinal preparations in indigenous systems of medicine to clean teeth or treat oral diseases such as periodontal disease. Herbal toothpaste is equally as good at controlling plaque and gingivitis as dentifrices made according to standard formulas. Streptococcus mutants, out of all the examined bacteria, were shown towards the most susceptible to the created dentifrice, as evidenced by a zone inhibition (7-8 mm), followed by Escherichia coli (7 mm), as well as oral micro-biota (8mm). The created Poly-herbal dentifrice was successfully tested using
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MAKWANA, DHARA, GALIB R, PARTH PRAKASHBHAI DAVE, MANJUSHA RAJAGOPALA, and PRADEEP KUMAR PRAJAPATI. "SHELF-LIFE ASSESSMENT OF DANTASHODHANA PASTE (A POLYHERBAL TOOTHPASTE): A PRELIMINARY STUDY." Asian Journal of Pharmaceutical and Clinical Research, February 7, 2020, 79–83. http://dx.doi.org/10.22159/ajpcr.2020.v13i4.35243.

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Objective: Shelf life is the period during which the potency (Virya) of a drug remains unaffected due to environmental factors or from microbial contamination. Considering the growing popularity of Ayurveda products, it becomes important to maintain the quality of all such products. Shelf life is one of the essential components under quality and needs to be evaluated for all products. Dantashodhana paste (DP) is a polyherbal toothpaste containing Vyosha (Zingiber officinale Roxb., Piper nigrum Linn., and Piper longum Linn.), Trijata (Cinnamomum zeylanicum Blume., Elettaria cardamomum Maton., C
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Thakur, Shifali, Bhawna Walia, and Gitika Chaudhary. "Dalchini (cinnamomum zeylanicum): a versatile spice with significant therapeutic potential." International Journal of Pharmaceutics and Drug Analysis, July 6, 2021, 126–36. http://dx.doi.org/10.47957/ijpda.v9i2.467.

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Cinnamomum zeylanicum is a widely utilized condiment for its therapeutic uses since ancient times. It is indigenous to Sri Lanka and Southern India. Cinnamon is one of the ancient spice which belongs to the Lauraceae family. In the modern era, it is widely used in industrial products like candies, chewing gums, mouthwash, and toothpaste. It is a well-considered plant remedy used in the treatment of many diseases in a traditional system like Ayurveda and the Folk system of medicine. It is used in many polyherbal formulations for curing various ailments. The plant is enriched with many vital oil
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