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Artykuły w czasopismach na temat „Porphyromonas gingivalis”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 25 lipca 2025

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1

Britos, Maria Rosenda, Cynthya Solange Sin, Silvia Mercedes Ortega, and Olga Miriam Vasek. "Diseño y estandarización de la técnica de PCR para Porphyromonas gingivalis." Revista de la Facultad de Odontología 10, no. 1 (2017): 25. http://dx.doi.org/10.30972/rfo.1012931.

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El objetivo del presente trabajo fue diseñar y estandarizar la técnica de PCR para detección en líquido gingival de Porphyromonas gingivalis, en pacientes con enfermedad periodontal. Material y métodos: Se utilizaron iniciadores específicos para el gen ARNr 16s de Porphyromonas gingivalis. La especificidad de los iniciadores se ensayó utilizando material genético extraído de la cepa de referencia Porphyromonas gingivalis ATCC 33277. Se ajustaron las condiciones de amplificación y concentraciones de la mezcla de reacción. Para validar la técnica se aplicó a diez muestras clínicas de líquido gin

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Griffen, Ann L., Mitzi R. Becker, Sharon R. Lyons, Melvin L. Moeschberger, and Eugene J. Leys. "Prevalence of Porphyromonas gingivalisand Periodontal Health Status." Journal of Clinical Microbiology 36, no. 11 (1998): 3239–42. http://dx.doi.org/10.1128/jcm.36.11.3239-3242.1998.

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Periodontitis is a common, progressive disease that eventually affects the majority of the population. The local destruction of periodontitis is believed to result from a bacterial infection of the gingival sulcus, and several clinical studies have provided evidence to implicate Porphyromonas gingivalis. If P. gingivalis is a periodontal pathogen, it would be expected to be present in most subjects with disease and rarely detected in subjects with good periodontal health. However, in most previous studies, P. gingivalis has not been detected in the majority of subjects with disease, and age-ma

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3

Reyes, Leticia. "Porphyromonas gingivalis." Trends in Microbiology 29, no. 4 (2021): 376–77. http://dx.doi.org/10.1016/j.tim.2021.01.010.

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Belibasakis, Georgios, Thomas Thurnheer, and Nagihan Bostanci. "Porphyromonas gingivalis." Virulence 5, no. 4 (2014): 463–64. http://dx.doi.org/10.4161/viru.28930.

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Indah Listiana Kriswandini, Amanda Sofi Nabila Maharani, Alisya Rachel Salsabila, and Tantiana. "Mechanism of inhibiting periodontitis pathogenesis with various variations of inhibitors on Porphyromonas gingivalis: Systematic literature review." World Journal of Advanced Research and Reviews 24, no. 3 (2024): 1172–77. https://doi.org/10.30574/wjarr.2024.24.3.3717.

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Background: Periodontal disease is the most prevalent disease worldwide with a prevalence of 20% to 50%, including periodontitis. Periodontitis involves complex interactions between specific pathogenic bacteria and host immune response. Microbial infections in subgingival biofilms are mainly caused by gram-negative bacteria including Porphyromonas gingivalis. Inhibition of Porphyromonas gingivalis virulence is one way to prevent periodontitis. This inhibition can be done in several ways through peptide inhibitors, quorum sensing inhibitors and natural inhibitors. Objective: This study aims to

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6

Andrian, E., D. Grenier, and M. Rouabhia. "Porphyromonas gingivalis-Epithelial Cell Interactions in Periodontitis." Journal of Dental Research 85, no. 5 (2006): 392–403. http://dx.doi.org/10.1177/154405910608500502.

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Emerging data on the consequences of the interactions between invasive oral bacteria and host cells have provided new insights into the pathogenesis of periodontal disease. Indeed, modulation of the mucosal epithelial barrier by pathogenic bacteria appears to be a critical step in the initiation and progression of periodontal disease. Periodontopathogens such as Porphyromonas gingivalis have developed different strategies to perturb the structural and functional integrity of the gingival epithelium. P. gingivalis adheres to, invades, and replicates within human epithelial cells. Adhesion of P.

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Nadhifah Salsabila, Nila Kasuma, and Eti Yerizel. "Determinasi Jumlah Bakteri Porphyromonas Gingivalis ATCC 33277 pada Saliva Anak Stunting." e-GiGi 12, no. 1 (2023): 26–31. http://dx.doi.org/10.35790/eg.v12i1.47864.

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Abstract: Nutrition affects the immune system and the development of oral health, including periodontal tissue health. Stunted children experience decreased salivary flow rate causing the growth of microorganisms that cause periodontal disease. Porphyromonas gingivalis is referred to one of the keystone pathogens in the development of periodontal disease. This study aimed to identify the number of Porphyromonas gingivalis ATCC 33277 bacteria in stunted child saliva. This was a descriptive study with a cross sectional design. Prior to collection, subjects were instructed to rinse their mouth fo

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Zhou, Yun, Maryta Sztukowska, Qian Wang та ін. "Noncanonical Activation of β-Catenin by Porphyromonas gingivalis". Infection and Immunity 83, № 8 (2015): 3195–203. http://dx.doi.org/10.1128/iai.00302-15.

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Porphyromonas gingivalisis an established pathogen in periodontal disease and an emerging pathogen in serious systemic conditions, including some forms of cancer. We investigated the effect ofP. gingivalison β-catenin signaling, a major pathway in the control of cell proliferation and tumorigenesis. Infection of gingival epithelial cells withP. gingivalisdid not influence the phosphorylation status of β-catenin but resulted in proteolytic processing. The use of mutants deficient in gingipain production, along with gingipain-specific inhibitors, revealed that gingipain proteolytic activity was

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9

Darveau, Richard P., Carol M. Belton, Robert A. Reife, and Richard J. Lamont. "Local Chemokine Paralysis, a Novel Pathogenic Mechanism for Porphyromonas gingivalis." Infection and Immunity 66, no. 4 (1998): 1660–65. http://dx.doi.org/10.1128/iai.66.4.1660-1665.1998.

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ABSTRACT Periodontitis, which is widespread in the adult population, is a persistent bacterial infection associated with Porphyromonas gingivalis. Gingival epithelial cells are among the first cells encountered by both P. gingivalis and commensal oral bacteria. The chemokine interleukin 8 (IL-8), a potent chemoattractant and activator of polymorphonuclear leukocytes, was secreted by gingival epithelial cells in response to components of the normal oral flora. In contrast, P. gingivalis was found to strongly inhibit IL-8 accumulation from gingival epithelial cells. Inhibition was associated wit

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10

Indah, Listiana Kriswandini, Sofi Nabila Maharani Amanda, Rachel Salsabila Alisya, and Tantiana. "Mechanism of inhibiting periodontitis pathogenesis with various variations of inhibitors on Porphyromonas gingivalis: Systematic literature review." World Journal of Advanced Research and Reviews 24, no. 3 (2024): 1172–77. https://doi.org/10.5281/zenodo.15187830.

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<strong>Background: </strong>Periodontal disease is the most prevalent disease worldwide with a prevalence of 20% to 50%, including periodontitis. Periodontitis involves complex interactions between specific pathogenic bacteria and host immune response. Microbial infections in subgingival biofilms are mainly caused by gram-negative bacteria including <em>Porphyromonas gingivalis</em>. Inhibition of <em>Porphyromonas gingivalis</em> virulence is one way to prevent periodontitis. This inhibition can be done in several ways through peptide inhibitors, quorum sensing inhibitors

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11

Enersen, Morten, Kazuhiko Nakano, and Atsuo Amano. "Porphyromonas gingivalis fimbriae." Journal of Oral Microbiology 5, no. 1 (2013): 20265. http://dx.doi.org/10.3402/jom.v5i0.20265.

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Nabila, Rina, Cicih Bhakti Purnamasari, and Alhawaris Alhawaris. "UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KAYU MANIS (Cinnamomum burmannii blume) TERHADAP PERTUMBUHAN BAKTERI Porphyromonas gingivalis DENGAN METODE DISC DIFFUSION." Jurnal Kedokteran Mulawarman 8, no. 2 (2021): 64. http://dx.doi.org/10.30872/j.ked.mulawarman.v8i2.6404.

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Periodontitis merupakan penyakit tertinggi keenam di seluruh dunia dengan Porphyromonas gingivalis sebagai salah satu bakteri penyebabnya. Daun kayu manis (Cinnamomum burmannii blume) menunjukkan beberapa aktivitas antimikroba, seperti antibakteri dan anti-jamur. Penelitian ini dilakukan untuk mengetahui aktivitas antibakteri ekstrak Cinnamomum burmannii blume terhadap pertumbuhan Porphyromonas gingivalis. Desain penelitian yang digunakan adalah the post test only control group design. Bakteri Porphyromonas gingivalis ditumbuhkan pada medium Blood Agar Plate (BAP) diberi perlakuan menggunakan

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13

Ibrahim, Jamilah, Sinar Yani, and Hadi Irawiraman. "Uji Efektifitas Ekstrak Etanol Bawang Tiwai (Eleutherine americana Merr) Terhadap Keadaan Klinis Tikus Periodontitis Yang Diinduksi Porphyromonas gingivalis." Mulawarman Dental Journal 1, no. 2 (2022): 48. https://doi.org/10.30872/molar.v1i2.5040.

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Background: Periodontitis is inflammation and infection that occurs in the periodontal tissue and alveolar bone supporting the teeth. Periodontal tissue examination should be performed to determine the severity of a periodontal disease. There are various kinds of examinations such as gingival index measurement, probing depth measurement, & bleeding on probing examination. Tiwai onions (Eleutherine americana Merr) have anti-inflammatory effects through the content of flavonoids and phenolic compounds. Objective: This study aims to determine the anti-inflammatory effectiveness of the ethanol

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14

Тюрин, С. М., О. Л. Мишутина, and Т. Г. Морозова. "THE STATE OF PERIODONTAL TISSUES IN PATIENTS WITH RHEUMATOID ARTHRITIS AND THE RESULTS OF PCR STUDIES OF THE MICROFLORA OF PERIODONTAL POCKETS." СИСТЕМНЫЙ АНАЛИЗ И УПРАВЛЕНИЕ В БИОМЕДИЦИНСКИХ СИСТЕМАХ 23, no. 3 (2024): 14–19. http://dx.doi.org/10.36622/1682-6523.2024.23.3.002.

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Обследовано 20 пациентов в возрасте от 35 до 60 лет с диагнозом ревматоидный артрит, страдающих хроническим пародонтитом и 30 пациентов с хроническим пародонтитом того же возраста без ревматоидного артрита и хронических заболеваний в стадии суб- и декомпенсации. Проводилось комплексное стоматологическое обследование больных и молекулярно-генетический скрининг микрофлоры пародонтальных карманов. По частоте выявления микроорганизмов в пародонтальных карманах в группе пациентов с ревматоидным артритом: на первом месте: Fusobacterium nucleatum (95% пациентов), на втором месте: Tanerella forsythia

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15

Jauregui, Catherine E., Qian Wang, Christopher J. Wright, Hiroki Takeuchi, Silvia M. Uriarte, and Richard J. Lamont. "Suppression of T-Cell Chemokines by Porphyromonas gingivalis." Infection and Immunity 81, no. 7 (2013): 2288–95. http://dx.doi.org/10.1128/iai.00264-13.

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ABSTRACTPorphyromonas gingivalisis a major pathogen in periodontal disease and is associated with immune dysbiosis. In this study, we found thatP. gingivalisdid not induce the expression of the T-cell chemokine IP-10 (CXCL10) from neutrophils, peripheral blood mononuclear cells (PBMCs), or gingival epithelial cells. Furthermore,P. gingivalissuppressed gamma interferon (IFN-γ)-stimulated release of IP-10, ITAC (CXCL11), and Mig (CXCL9) from epithelial cells and inhibited IP-10 secretion in a mixed infection with the otherwise stimulatoryFusobacterium nucleatum. Inhibition of chemokine expressio

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16

Waller, Tobias, Laura Kesper, Josefine Hirschfeld, et al. "Porphyromonas gingivalis Outer Membrane Vesicles Induce Selective Tumor Necrosis Factor Tolerance in a Toll-Like Receptor 4- and mTOR-Dependent Manner." Infection and Immunity 84, no. 4 (2016): 1194–204. http://dx.doi.org/10.1128/iai.01390-15.

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Porphyromonas gingivalisis an important member of the anaerobic oral flora. Its presence fosters growth of periodontal biofilm and development of periodontitis. In this study, we demonstrated that lipophilic outer membrane vesicles (OMV) shed fromP. gingivalispromote monocyte unresponsiveness to liveP. gingivalisbut retain reactivity to stimulation with bacterial DNA isolated fromP. gingivalisor AIM2 ligand poly(dA·dT). OMV-mediated tolerance ofP. gingivalisis characterized by selective abrogation of tumor necrosis factor (TNF). Neutralization of interleukin-10 (IL-10) during OMV challenge par

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17

Peeran, Syed Wali, Manohar Murugan, Nagabhushana Doggalli, et al. "Herbal Composite Preparation and Investigating its Efficiency to Inhibit Biofilm Formation and Virulence Factors of Prevotella Intermedia and Porphyromonas Gingivalis – Formulation of Mouthwash Using a Herbal Composite and Evaluating its Anti-microbial Activity." Journal of Pharmacy and Bioallied Sciences 16, Suppl 2 (2024): S1574—S1584. http://dx.doi.org/10.4103/jpbs.jpbs_998_23.

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ABSTRACT Herbal composite preparation was studied with the aim of inhibiting the virulence factors of two dental pathogens: Prevotella intermedia and Porphyromonas gingivalis. A novel herbal composite was developed using the herbal extracts of Wrightia tinctoria and Bauhinia variegata. During the study, the following observations were noted. The minimal inhibitory concentration of Wrightia tinctoria and Bauhinia variegata composites (WBc) was obtained for the test concentration of 20 μg/ml (16 ± 0.57 mm and 15 ± 0.75 mm of inhibitory zones against Prevotella intermedia and Porphyromonas gingiv

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Ardhani, Retno, Rasda Diana, and Bidhari Pidhatika. "How Porphyromonas gingivalis Navigate the Map: The Effect of Surface Topography on the Adhesion of Porphyromonas gingivalis on Biomaterials." Materials 15, no. 14 (2022): 4988. http://dx.doi.org/10.3390/ma15144988.

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The main purpose of this study is to develop an understanding of how Porphyromonas gingivalis responds to subperiosteal implant surface topography. A literature review was drawn from various electronic databases from 2000 to 2021. The two main keywords used were “Porphyromonas gingivalis” and “Surface Topography”. We excluded all reviews and or meta-analysis articles, articles not published in English, and articles with no surface characterization process or average surface roughness (Ra) value. A total of 26 selected publications were then included in this study. All research included showed

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Sampe, Fatrisia S., Janno B. B. Bernadus, and Juliatri Juliatri. "Uji Daya Hambat Virgin Coconut Oil terhadap Pertumbuhan Bakteri Porphyromonas gingivalis." e-GiGi 14, no. 1 (2025): 7–12. https://doi.org/10.35790/eg.v14i1.61278.

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Abstract: Porphyromonas gingivalis is a type of bacteria that commonly causes periodontal disease. Several studies have revealed that virgin coconut oil (VCO) is able to provide antibacterial effects due to its high fatty acid content, especially lauric acid. This study aimed to identify the ability of VCO to inhibit the growth of Porphyromonas gingivalis bacteria. This test used the disc diffusion method. Samples of VCO were taken from the Agricultural Instrument Standardization Agency (BSIP) for palm plants which were processed using the dry method and made into concentrations of 25%, 50%, 7

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Lamont, R. J., A. Chan, C. M. Belton, K. T. Izutsu, D. Vasel, and A. Weinberg. "Porphyromonas gingivalis invasion of gingival epithelial cells." Infection and immunity 63, no. 10 (1995): 3878–85. http://dx.doi.org/10.1128/iai.63.10.3878-3885.1995.

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Rudy, Joelijanto, Corvianindya Rahayu Yani, Sutjiati Rina, and . Sulistyani. "Effect of Cocoa Pod Husk Proanthocyanidins Extract on Cyclooxigenase-2 (COX-2) Expression in Gingival Crevicular Fluid of Periodontitis Rats." International Journal Of Medical Science And Clinical Research Studies 03, no. 06 (2023): 1198–202. https://doi.org/10.5281/zenodo.8096987.

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Inflammation of periodontal tissue due to Porphyromonas gingivalis which invades the gingival tissue due to the activity of virulence factors. This causes the host immune system changes and increases COX-2 production in periodontal tissue so resulting excessive tissue destruction. The aim of this study was to analyze the potency of proanthocyanidins extract of cacao pod husk to inhibit COX-2 expression in rat gingival sulcus fluid. 3 groups in this study, namely negative control, positive control, and treatment. In all groups, on the 0 day, gingival sulcus fluid was taken, then the rats were i

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Wang, Yu-Hsiung, Jin Jiang, Qiang Zhu, et al. "Porphyromonas gingivalis Lipids Inhibit Osteoblastic Differentiation and Function." Infection and Immunity 78, no. 9 (2010): 3726–35. http://dx.doi.org/10.1128/iai.00225-10.

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ABSTRACT Porphyromonas gingivalis produces unusual sphingolipids that are known to promote inflammatory reactions in gingival fibroblasts and Toll-like receptor 2 (TLR2)-dependent secretion of interleukin-6 from dendritic cells. The aim of the present study was to examine whether P. gingivalis lipids inhibit osteoblastic function. Total lipids from P. gingivalis and two fractions, phosphoglycerol dihydroceramides and phosphoethanolamine dihydroceramides, were prepared free of lipid A. Primary calvarial osteoblast cultures derived from 5- to 7-day-old CD-1 mice were used to examine the effects

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Khasyiun, Muhammad Rijal dermawan, Mudyawati Kamaruddin, and Steffi Triany Arnov. "UJI EFEKTIVITAS EKSTRAK ETANOL BUAH JAMBU BIJI MERAH (Psidium guajava L.) DALAM MENGHAMBAT PERTUMBUHAN BAKTERI Porphyromonas Gingivalis PENYEBAB PERIODONTITIS." Indonesian Journal of Dentistry 3, no. 1 (2023): 31. http://dx.doi.org/10.26714/ijd.v3i1.11991.

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Pendahuluan: Penyakit periodontal bentuk gangguan Kesehatan gigi dan mulut yang memiliki prevalensi cukup besar di Indonesia sebesar 74,1%. Peyakit periodontal jika dibiarkan akan menimbulkan kehilangan perlekatan dan pembentukan poket atau kantung periodontal yang diakibatkan oleh perkembangan bakteri patogen. Porphyromonas gingivalis merupakan bakteri terbanyak penyebab periodontitis kronis yaitu mencapai 96,2%. Perawatan mekanik yang dapat diberikan adalah scaling, root planing, dan kuretase Selain itu, perawatan periodontitis dengan menggunakan terapi medikamen antibiotik. Psidium guajava

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Trocha–Mendoza, María José, and Catalina María Arévalo–Caro. "Relación entre Porphyromonas gingivalis y diabetes mellitus tipo 2: revisión sistemática exploratoria." Acta Odontológica Colombiana 11, no. 2 (2021): 10–24. http://dx.doi.org/10.15446/aoc.v11n2.95219.

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Objetivo: analizar la relación entre Porphyromonas gingivalis y diabetes mellitus tipo 2, mediante una revisión sistemática exploratoria de la literatura científica publicada entre los años 2000 y 2019. Métodos: se utilizaron los siguientes términos MeSH: Porphyromonas gingivalis, diabetes mellitus type 2, periodontal disease, non insulin dependent diabetes. Se obtuvieron 346 resultados, de los cuales se seleccionaron 41 por título, se excluyeron 11 posterior a la lectura del abstract e introducción y 19 después de la lectura del texto completo. Finalmente, se incluyeron 11 artículos. Resultad

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Luo, Shiyin, Tong Xu, Qifan Zheng, et al. "Mitochondria: An Emerging Unavoidable Link in the Pathogenesis of Periodontitis Caused by Porphyromonas gingivalis." International Journal of Molecular Sciences 25, no. 2 (2024): 737. http://dx.doi.org/10.3390/ijms25020737.

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Porphyromonas gingivalis (P. gingivalis) is a key pathogen of periodontitis. Increasing evidence shows that P. gingivalis signals to mitochondria in periodontal cells, including gingival epithelial cells, gingival fibroblast cells, immune cells, etc. Mitochondrial dysfunction affects the cellular state and participates in periodontal inflammatory response through the aberrant release of mitochondrial contents. In the current review, it was summarized that P. gingivalis induced mitochondrial dysfunction by altering the mitochondrial metabolic state, unbalancing mitochondrial quality control, pr

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Ramos Perfecto, Donald, Hilda Moromi Nakata, and Elba Martínez Cadillo. "Porphyromonas gingivalis:patógeno predominante en la periodontitis crónica." Odontología Sanmarquina 14, no. 1 (2014): 34. http://dx.doi.org/10.15381/os.v14i1.2907.

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Porphyromonas gingivales es un bacilo gram negativo predominante en la Periodontitis crónica, sus múltiples factores de virulencia la hacen sumamente agresiva. En el surco gingival encuentra las condiciones para su crecimiento, interaccionando con el huésped produciendo una destrucción lenta pero constante de los tejidos del periodonto. Su predominancia ha sido considerada como un factor de riesgos para enfermedades sistémicas inflamatorios, como la del infarto de miocardio. Aunque su susceptibilidad a una diversidad de fármacos hace posible su manejo con antimicrobianos previa remoción mecáni

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Kim, Hey-Min, Christina Magda Rothenberger, and Mary Ellen Davey. "Cortisol Promotes Surface Translocation of Porphyromonas gingivalis." Pathogens 11, no. 9 (2022): 982. http://dx.doi.org/10.3390/pathogens11090982.

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Studies are showing that the stress hormone cortisol can reach high levels in the gingival sulcus and induce shifts in the metatranscriptome of the oral microbiome. Interestingly, it has also been shown that cortisol can influence expression levels of Type IX Secretion System (T9SS) genes involved in gliding motility in bacteria belonging to the phylum Bacteroidota. The objective of this study was to determine if cortisol impacts gene expression and surface translocation of Porphyromonas gingivalis strain W50. To conduct these experiments, P. gingivalis was stabbed to the bottom of soft agar p

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Muharammy, Fairuza, Rizanda Machmud, and Surya Nelis. "PERBEDAAN DAYA HAMBAT OBAT ANESTESI LOKAL LIDOCAINE 2% DAN ARTICAINE 4% TERHADAP PERTUMBUHAN BAKTERI Porphyromonas gingivalis SECARA IN VITRO." Andalas Dental Journal 4, no. 2 (2016): 89–97. http://dx.doi.org/10.25077/adj.v4i2.58.

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Porphyromonas gingivalis is a gram-negative anaerobic bacteria which is an oral normal microflora located in subgingival area.This bacteria can cause inflamation and delayed wound healing after dental invasive procedures. Lidocaine 2% and articaine 4% are the most used anaesthetic agents in dentistry. Both of these agents have been studied for having antibacterial effect in certain concentrations. This will open the possibility of using local anaesthetic agents as antibacterial agent in dental invasive procedures to prevent infection after procedures. The purpose of this study is to analyze th

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Khotimah, Destri Khusnul, I. Wayan Arya Krishnawan Firdaus, and Maharani Laillyza Apriasari. "THE INHIBITORY ACTIVITY OF KELAKAI LEAF EXTRACT AGAINST THE GROWTH OF Porphyromonas gingivalis ATCC® 33277™." Dentino : Jurnal Kedokteran Gigi 5, no. 2 (2020): 104. http://dx.doi.org/10.20527/dentino.v5i2.8945.

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ABSTRACTBackground: Chronic periodontitis is an infectious disease that causes damage on periodontal ligament and alveolar bone. The severity of periodontitis is caused by several types of bacterial species which one of them is Porphyromonas gingivalis bacteria with a prevalence of 85% in oral cavity. The extract of kelakai leaf contained antibacterial in the form of flavonoid, alkaloid, tannin, and steroid. Flavonoid consists of some chemical compounds which is one of them is quercetin. The level of quercetin in kelakai leaf is 503.56 mgQE/g. From some secondary metabolites, kelakai leaf has

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Drucker, David B., Ali M. Tavana, Valerie Boote, and Daria N. Love. "Is Porphyromonas gingivalis heterogeneous?" Reviews in Medical Microbiology 8 (1997): S13. http://dx.doi.org/10.1097/00013542-199712001-00004.

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Igboin, C. O., A. L. Griffen, and E. J. Leys. "Porphyromonas gingivalis Strain Diversity." Journal of Clinical Microbiology 47, no. 10 (2009): 3073–81. http://dx.doi.org/10.1128/jcm.00569-09.

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Dwipriastuti, Devi, R. Rama Putranto, and Welly Anggarani. "PERBEDAAN EFEKTIVITAS CHLORHEXIDINE GLUKONAT 0,2% DENGAN TEH HIJAU (CAMELLIA SINENSIS) TERHADAP JUMLAH PORPHYROMONAS GINGIVALIS." ODONTO : Dental Journal 4, no. 1 (2017): 50. http://dx.doi.org/10.30659/odj.4.1.50-54.

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Background: Periodontitis is a periodontal inﬂammation caused by plaque that contains pathogens, Porphyromonas gingivalis is one of them. Chlorhexidine therapy used to reduce the number of pathogenic bacteria causing periodontitis. Green tea contains polyphenols such as epigallocatechin-3-gallic as antibacterial agent that can kill the bacteria Porphyromonas gingivalis. This study aims to determine diﬀerences in the eﬀectiveness of chlorhexidine gluconate 0.2% with green tea (Camellia sinensis) various concentrations to decrease the amount of bacteria Porphyromonas gingivalis.Method: This rese

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Wedarti, Yoifah Rizka, Laurencia Isabella Loekito, Fani Pangabdian, and Dwi Andriani. "Potensi kitosan kepiting rajungan (Portunus pelagicus) dalam penghambatan pembentukan biofilm Porphyromonas gingivalis dan pertumbuhan Candida albicansPotential of flower crab (Portunus pelagicus) chitosan in the inhibition of Porphyromonas gingivalis and Candida albicans biofilm." Padjadjaran Journal of Dental Researchers and Students 4, no. 2 (2020): 121. http://dx.doi.org/10.24198/pjdrs.v4i2.26636.

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Pendahuluan: Pembentukan biofilm sangat penting dalam patogenesis periodontitis. Porphyromonas gingivalis merupakan bakteri yang banyak ditemukan pada plak gigi dan memiliki kemampuan membentuk biofilm demikian juga Candida albicans memiliki faktor virulensi yang dapat membantu kolonisasi dan proliferasi bakteri di dalam poket periodontal. Ekstrak kitosan kepiting rajungan (Portunus pelagicus) mempunyai potensi antimikrobial yang dapat digunakan sebagai alternatif terapi. Tujuan penelitian ini adalah untuk menganalisis potensi kitosan kepiting rajungan (Portunus pelagicus) dalam penghambatan b

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Sylvana, Dini, Masyhudi Amir, Cicih Bhakti Purnamasari, Abdillah Iskandar, and Verry Asfirizal. "Antibacterial activity of ethanol extract of Beluntas leaves on Streptococcus mutans, Porphyromonas gingivalis, and Enterococcus faecalis." Padjadjaran Journal of Dentistry 33, no. 3 (2021): 191. http://dx.doi.org/10.24198/pjd.vol33no3.19133.

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Introduction: Individuals with poor oral health have a greater risk factor for systemic diseases. Caries, periodontal disease, and root canal infections are a common dental and oral diseases caused by dominance of Streptococcus mutans, Porphyromonas gingivalis, and Enterococcus faecalis bacteria (S. mutans, P. gingivalis, and E. faecalis). An alternative way to prevent dental and oral diseases is to use herbal medicine as one of the active ingredients for mouthwash or toothpaste. One of the herbs that can be used is Beluntas leaves (Pluchea indica (L.) Less leaves). The objective of study was

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Fitria, Novita Nanda, Beta Widya Oktiani, and Aulia Azizah. "ANTIBACTERIAL EFFECTIVENESS TEST OF KECAPI LEAVES EXTRACTS (Sandoricum koetjape) AGAINST THE GROWTH OF Porphyromonas gingivalis." Dentino: Jurnal Kedokteran Gigi 9, no. 1 (2024): 18. http://dx.doi.org/10.20527/dentino.v9i1.18855.

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Background: Chronic periodontitis is a disease of the oral cavity that is influenced by the presence of plaque bacteria caused by Porphyromonas gingivalis which can cause chronic infection of the periodontal tissue. Kecapi leaf (Sandoricum koetjape) extract contains active compounds in the form of flavonoids, saponins, alkaloids, steroids, phenolics, and triterpenoids which function as antibacterial against the growth of Porphyromonas gingivalis. Kecapi leaf extract is used as an alternative to using herbal gluconate to prevent infection caused of Porphyromonas gingivalis. Purpose: To determin

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Mei, Feng, Mengru Xie, Xiaofei Huang, et al. "Porphyromonas gingivalis and Its Systemic Impact: Current Status." Pathogens 9, no. 11 (2020): 944. http://dx.doi.org/10.3390/pathogens9110944.

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The relationship between periodontitis and systemic diseases, notably including atherosclerosis and diabetes, has been studied for several years. Porphyromonas gingivalis, a prominent component of oral microorganism communities, is the main pathogen that causes periodontitis. As a result of the extensive analysis of this organism, the evidence of its connection to systemic diseases has become more apparent over the last decade. A significant amount of research has explored the role of Porphyromonas gingivalis in atherosclerosis, Alzheimer’s disease, rheumatoid arthritis, diabetes, and adverse

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Angriani, Asti, Yasnidar Yasir, and Rusli. "Uji Aktivitas Antibakteri Getah Jarak Pagar Asal Kabupaten Gowa Terhadap Bakteri Penyebab Karies pada Gigi." Jurnal Novem Medika Farmasi 3, no. 1 (2024): 62–71. http://dx.doi.org/10.59638/junomefar.v3i1.782.

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Tanaman getah jarak pagar (Jatropha curcas L.) mengandung flavonoid, dan tanin yang berpotensi sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri dan konsentrasi efektif getah jarak pagar terhadap Porphyromonas gingivalis dan Streptococcus mutans. Getah jarak pagar diambil langsung dari batangnya dengan cara memotong batangnya dengan menggunakan pisau aseptik dan di tampung dalam botol vial. Pengujian aktivitas antibakteri getah jarak pagar terhadap Porphyromonas gingivalis dan Streptococcus mutans menggunakan metode dilusi cair dan difusi agar. Hasil peneliti

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Albert and Syifa Ameliya Az-Zahra. "Potensi Antibakteri Ekstrak (Graptophyllum Pictum (L.) Griff) Pada Porphyromonas gingivalis." Jurnal Kedokteran Gigi Terpadu 6, no. 1 (2024): 45–49. http://dx.doi.org/10.25105/jkgt.v6i1.20854.

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Background: The most prevalent bacteria found in periodontitis are the Gram-negative anaerobic stem bacteria Porphyromonas gingivalis. Periodontitis can potentially affect tooth mobility and tooth loss. Plaque control can be achieved using mechanical tools such as toothbrushes and interdental cleaners, which are reinforced by the use of antibacterial remedies as a chemical approach. Purple leaves contain chemical compounds including alkaloids, flavonoids, tannins, tripenoids, saponins, and glycosides. Objective: To determine the effectiveness of purple leaves as an antibacterial inhibitor agai

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Supriya P, Sayeeda Laeque Bangi, and Prasad Konda. "An evaluation and comparison for the presence of aggregatibacter actinomycetemcomitans, porphyromonas gingivalis levels in patients with pea and self- ligating brackets." IP Indian Journal of Orthodontics and Dentofacial Research 10, no. 4 (2024): 232–39. http://dx.doi.org/10.18231/j.ijodr.2024.041.

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Subgingival periodontal biofilm/plaque is accumulated with as Aggregatibacter actinomycetemcomitans (AA), Porphyromonas gingivalis (PG), Prevotella intermedia(PI), Tannerella forsythia(TF), and Treponema denticola(TD) causing periodontitis. : The aim was to evaluate and compare the levels of Aggregatebacter actinomycetemcomitans(AA) and Porphyromonas gingivalis(PG) in the gingival crevicular fluids of the patients undergoing orthodontic treatment with PEA(MBT Prescription; 3M Unitek) and Passive Self-ligating Brackets(Damon Q; ORMCO).The GCF was collected at baseline, 3 months and 6 months dur

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Zhang, Jinrong, Leah Cole, Anna Brown, Bing Ma, Natalie Anosova, and Jacqueline McCluskey. "Development of a RANKL ELISPOT assay as a tool for periodontal disease research (TECH2P.913)." Journal of Immunology 194, no. 1_Supplement (2015): 206.23. http://dx.doi.org/10.4049/jimmunol.194.supp.206.23.

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Abstract Periodontal disease (PD) results from the immune response to the bacterial components of the sub-gingival plaque. PD progresses from gingival inflammation, to bone resorption and ultimately tooth loss. Receptor activator of nuclear factor-kappa B ligand (RANKL) is critical for regulating inflammatory bone resorption. Studies have shown that activated T and B cells are one of the main sources of RANKL in PD. The ELISPOT assay is widely used tool that can measure antigen specific cellular immune responses. We developed a RANKL specific ELISPOT assay for quantifying the number of RANKL s

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Sarwat, Tarana, Lipika Gaur, Zarine Khan, Pranjalika Phukan, and Dalip K. Kakru. "Porphyromonas gingivalis in Dental Caries: Prevalence and Association with Diabetes and Smoking." Journal of Medical Sciences and Health 10, no. 3 (2025): 253–57. https://doi.org/10.46347/jmsh.v10.i3.24.149.

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Background and objectives: Porphyromonas gingivalis is an intraoral anaerobic bacterium that causes periodontal disease. Diabetes and smoking are thought to be the main associated risk factors. The aim of this study was to assess the prevalence of P. gingivalis in periodontitis patients and to determine its association with diabetes and smoking. Methods: This three - month cross-sectional study was conducted in the department of Microbiology, Sharda Hospital, Greater Noida. 38 plaque samples were collected and cultured anaerobically to look for the growth of Porphyromonas gingivalis. Results:

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Suzuki, Mitsuo, Toshizo Toyama, Kiyoko Watanabe, et al. "Ameliorating Effects of Jixueteng in a Mouse Model of Porphyromonas gingivalis-Induced Periodontitis: Analysis Based on Gingival Microcirculatory System." Natural Product Communications 13, no. 12 (2018): 1934578X1801301. http://dx.doi.org/10.1177/1934578x1801301230.

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Jixueteng, the dried stem of Spatholobus suberectus Dunn (Leguminosae), is a traditional Chinese herbal medicine that promotes blood circulation and can be used to treat blood stasis. In this study, we aimed to investigate the potential of Jixueteng as a preventive and therapeutic drug for periodontitis. We investigated the inhibitory effects of Jixueteng on Porphyromonas gingivalis ( P. gingivalis)-induced gingival circulatory disturbances in mice. Seventy-two male C57BL/6N mice (4-week-old) were randomly divided into the following four groups of 12 mice each. Group 1 served as the P. gingiva

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Luthfiyani, Anisa, Peni Pujiastuti, and Melok Aris W. "Daya Antibakteri Ekstrak Daun Seledri (Apium graveolens L.) terhadap Porphyromonas gingivalis." STOMATOGNATIC - Jurnal Kedokteran Gigi 16, no. 2 (2019): 53. http://dx.doi.org/10.19184/stoma.v16i2.23092.

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Background: celery leaves contain antibacterial substances that can be used as medicine. These contents include flavonoids, saponins and tannins. Purpose: the aim of this study was to determine the antibacterial effect of celery leaves (Apium graveolens L.) on the growth of Porphyromonas gingivalis (P. gingivalis). Methods: celery leaves were extracted by maceration method with 96% ethanol. The antibacterial test method against P. gingivalis using the well diffusion method on BHI-A media. The concentrations of celery leaf extract used in this study were 6.25%, 12.5%, 25%, 50% and 100%. Result:

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Chaudhuri, Swarnava, Siddharth Pratap, Victor Paromov, Zhijun Li, Chinmay K. Mantri, and Hua Xie. "Identification of a Diguanylate Cyclase and Its Role in Porphyromonas gingivalis Virulence." Infection and Immunity 82, no. 7 (2014): 2728–35. http://dx.doi.org/10.1128/iai.00084-14.

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ABSTRACTPorphyromonas gingivalisis a Gram-negative obligate anaerobic bacterium and is considered a keystone pathogen in the initiation of periodontitis, one of the most widespread infectious diseases. Bacterial bis-(3′-5′) cyclic GMP (cyclic di-GMP [c-di-GMP]) serves as a second messenger and is involved in modulating virulence factors in numerous bacteria. However, the role of this second messenger has not been investigated inP. gingivalis, mainly due to a lack of an annotation regarding diguanylate cyclases (DGCs) in this bacterium. Using bioinformatics tools, we found a protein, PGN_1932,

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MORIOKA, Masami, Mika UEDA, Kanako YAMATO, et al. "Aggregation of Human Gingival Fibroblasts by Porphyromonas gingivalis." JOURNAL OF DENTAL HEALTH 44, no. 1 (1994): 116–21. http://dx.doi.org/10.5834/jdh.44.116.

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Andrian, Elisoa, Daniel Grenier, and Mahmoud Rouabhia. "In Vitro Models of Tissue Penetration and Destruction by Porphyromonas gingivalis." Infection and Immunity 72, no. 8 (2004): 4689–98. http://dx.doi.org/10.1128/iai.72.8.4689-4698.2004.

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ABSTRACT Porphyromonas gingivalis is a gram-negative anaerobic bacterium that is considered the key etiologic agent of chronic periodontitis. Arg- and Lys-gingipain cysteine proteinases produced by P. gingivalis are key virulence factors and are believed to be essential for significant tissue component degradation, leading to host tissue invasion by periodontopathogens. Two in vitro models were used to determine the extent to which P. gingivalis can reach connective tissue. The tissue penetration potential of P. gingivalis was first investigated by using an engineered human oral mucosa model c

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Yilmaz, Özlem, Patrick A. Young, Richard J. Lamont, and George E. Kenny. "Gingival epithelial cell signalling and cytoskeletal responses to Porphyromonas gingivalis invasion." Microbiology 149, no. 9 (2003): 2417–26. http://dx.doi.org/10.1099/mic.0.26483-0.

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Porphyromonas gingivalis, an oral pathogen, can internalize within primary gingival epithelial cells (GECs) through an invasion mechanism mediated by interactions between P. gingivalis fimbriae and integrins on the surface of the GECs. Fimbriae–integrin-based signalling events were studied by fluorescence microscopy, and the subcellular localization of integrin-associated signalling molecules paxillin and focal adhesion kinase (FAK), and the architecture of the actin and microtubule cytoskeleton were examined. GECs infected with P. gingivalis for 30 min demonstrated significant redistribution

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Eskan, Mehmet A., George Hajishengallis, and Denis F. Kinane. "Differential Activation of Human Gingival Epithelial Cells and Monocytes by Porphyromonas gingivalis Fimbriae." Infection and Immunity 75, no. 2 (2006): 892–98. http://dx.doi.org/10.1128/iai.01604-06.

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ABSTRACT Humans develop periodontitis in response to challenge by microbial dental plaque. Inflammation begins after perturbation of gingival epithelial cells by subgingival bacteria interacting through pattern-recognition receptors, including the Toll-like receptors (TLR). Porphyromonas gingivalis is a major periodontopathogen that interacts with epithelial cells through its cell surface fimbriae (FimA), leading to colonization and/or invasion. Previous work by our group has established membrane CD14 as an essential coreceptor for TLR2-mediated activation of transfected cell lines by P. gingi

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Hepitaria, Nova Andriani, Indeswati Diyatri, Markus Budi Rahardjo, and Rini Devijanti Ridwan. "The potency of Immunoglobulin Y anti Porphyromonas gingivalis to inhibit the adherence ability of Porphyromonas gingivalis on enterocytes." Dental Journal (Majalah Kedokteran Gigi) 53, no. 1 (2020): 20. http://dx.doi.org/10.20473/j.djmkg.v53.i1.p20-23.

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Background: Pophyromonas gingivalis (P. gingivalis) bacteria are the main type of bacterium that cause chronic periodontitis. Immunoglobulin Y (IgY) is a type of immunoglobulin found in poultry, such as chickens and birds. IgY can be used as an alternative method of preventing the accumulation of plaque that causes chronic periodontitis. Purpose: To determine the ability of IgY anti P. gingivalis to inhibit adherence of P. gingivalis. Methods: The samples were divided into eight groups, each group containing 10 ml of IgY anti P. gingivalis and 50 ml of enterocyte cells. The control group conta

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Muharammy, Fairuza, Rizanda Machmud, and Surya Nelis. "Perbedaan Daya Hambat Obat Anestesi Lokal Lidocaine 2% dan Articaine 4% Terhadap Pertumbuhan Bakteri Porphyromonas Gingivalis Secara In Vitro." Andalas Dental Journal 4, no. 2 (2016): 79–87. http://dx.doi.org/10.25077/adj.v4i2.159.

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Porphyromonas gingivalis is a gram-negative anaerobic bacteria which is an oral normal microflora located in subgingival area.This bacteria can cause inflamation and delayed wound healing after dental invasive procedures. Lidocaine 2% and articaine 4% are the most used anaesthetic agents in dentistry. Both of these agents have been studied for having antibacterial effect in certain concentrations. This will open the possibility of using local anaesthetic agents as antibacterial agent in dental invasive procedures to prevent infection after procedures. The purpose of this study is to analyze th

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