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Artykuły w czasopismach na temat „Pregnancy associated osteopenia”

Autor: Grafiati

Data publikacji: 2 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Dolgova, L. N., and I. G. Krasivina. "Disorders of bone mineral density associated with pregnancy and lactation (a literature review)." Medical Council, no. 2 (December 30, 2016): 32–35. http://dx.doi.org/10.21518/2079-701x-2016-2-32-35.

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Traditionally, the problem of osteoporosis (OP) and osteopenia (OPe) in women is associated with the period of menopause. Increased bone fragility and osteoporotic fractures in pregnant, postpartum and breast-feeding women is less expected but the socio-economic burden can be significant. Neither the existing classification of OP nor the International Classification of Diseases separate OP associated with pregnancy, childbirth and lactation [1].

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Paul, Prannoy, Balaji Zacharia, Sreenath Sreekumar, Anoop J. Mattam, Anoop Antony, and K. S. Greeshma. "Pregnancy-Associated Osteoporosis – A Rare Cause of Subchondral Fracture of Femoral Head: A Case Report." Journal of Orthopaedic Case Reports 14, no. 1 (2024): 31–35. http://dx.doi.org/10.13107/jocr.2024.v14.i01.4136.

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Introduction: Pregnancy- and lactation-associated osteoporosis (PLAO) is a rare cause of back pain during pregnancy and puerperium. We report a rare case of PLAO with subchondral fracture of the femoral head. Case Report: A 19-year-old second gravida presented with severe back pain and an inability to ambulate due to pain in the right buttock during the puerperium. The pain started during the last trimester and was aggravated after delivery. Her radiogram showed multiple compression fractures with osteopenia in the dorsolumbar spine. A magnetic resonance imaging scan of the pelvis showed bone

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Velychko, V., L. Kolotvyna, O. Said, M. Postolenko та L. Korolyova. "Current Issues of Osteoporosis in Women Patients in Family Practice = Некоторые актуальные вопросы остеопороза у женщин в практике семейного врача". Journal of Education, Health and Sport formerly Journal of Health Sciences 4, № 10 (2014): 315–21. https://doi.org/10.5281/zenodo.12421.

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<strong>Velychko V</strong><strong>.</strong><strong>I</strong><strong>., </strong><strong>Kolotvyna L</strong><strong>.</strong><strong>I</strong><strong>., </strong><strong>Said O</strong><strong>.</strong><strong>V</strong><strong>., </strong><strong>Postolenko M</strong><strong>.</strong><strong>O</strong><strong>., </strong><strong>Korolyova L</strong><strong>.</strong><strong>A</strong><strong>.</strong> <strong>Current Issues of Osteoporosis in Women Patients in Family Practice = </strong><strong>Некоторые актуальные вопросы остеопороза у женщин</strong> <strong>в практике семейного вра

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Ferrari, Vittorio, Giacomo Biasucci, Egidio Candela, Rita Ortolano, Federico Baronio, and Marcello Lanari. "Clinical Implications and Preventive Strategies for Neonatal and Infant Hypovitaminosis D: Analysis and Comparison of Current Evidence." Endocrines 6, no. 2 (2025): 21. https://doi.org/10.3390/endocrines6020021.

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Background: Vitamin D is essential for neonatal health, with maternal vitamin D status crucial in fetal development and neonatal outcomes. During pregnancy, vitamin D is transferred to the fetus via the placenta, forming an initial reserve. Postnatally, neonates rely on maternal levels and supplementation due to limited sunlight exposure and immature skin synthesis. Objectives: This review evaluates neonatal vitamin D deficiency’s causes and clinical consequences, emphasizing its impact on newborn and infant health. Results: Maternal vitamin D levels strongly correlate with neonatal 25(OH)D co

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Palmacci, Francesca, Elisabetta Toti, Anna Raguzzini, et al. "Neutrophil-to-Lymphocyte Ratio, Mediterranean Diet, and Bone Health in Coeliac Disease Patients: A Pilot Study." Oxidative Medicine and Cellular Longevity 2019 (June 20, 2019): 1–14. http://dx.doi.org/10.1155/2019/7384193.

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Neutrophil-to-lymphocyte ratio (NLR) has been proposed as a bone loss index in postmenopausal women and as a marker of inflammation in coeliac patients. The aims of this work were to evaluate the effect of gluten-free diet (GFD) on NLR retrospectively and study the relationship between NLR and Mediterranean diet adherence and selected food groups (fruits, vegetables, red meat, potatoes, and unrefined and refined cereals). Adult individuals (n=50), who had been on a strict GFD by at least 6 months, were recruited. The degree of adherence to the Mediterranean diet was calculated with two differe

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Rodger, Marc A., Alejandro Lazo-Langner, Susan Kahn, et al. "Prophylactic Low Molecular Weight Heparin (LMWH) during Pregnancy Is Not Associated with a Decrease in Bone Mineral Density (BMD). The TIPPS (Thrombophilia in Pregnancy Prophylaxis Study) BMD Substudy." Blood 106, no. 11 (2005): 548. http://dx.doi.org/10.1182/blood.v106.11.548.548.

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Abstract Background: Decreased BMD is a relatively common serious complication of long-term heparin use, however there have not been adequately powered randomized controlled trials addressing its risk in association with long-term use of LMWH. The TIPPS study is an ongoing multi-center randomized trial designed to compare the effect of LMWH prophylaxis vs. no prophylaxis on pregnancy outcomes in thrombophilic pregnant women. A separate sub-study was planned a priori to assess the effect of LMWH on BMD. Methods: Pregnant women (&lt;20 weeks) were included if they had history of: pregnancy c

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Shapiro, Charles L., Judith Manola, and Meryl Leboff. "Ovarian Failure After Adjuvant Chemotherapy Is Associated With Rapid Bone Loss in Women With Early-Stage Breast Cancer." Journal of Clinical Oncology 19, no. 14 (2001): 3306–11. http://dx.doi.org/10.1200/jco.2001.19.14.3306.

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PURPOSE: We sought to evaluate the effects of chemotherapy-induced ovarian failure on bone loss and markers of skeletal turnover in a prospective longitudinal study of young women with breast cancer receiving adjuvant chemotherapy. PATIENTS AND METHODS: Forty-nine premenopausal women with stage I/II breast cancers receiving adjuvant chemotherapy were evaluated within 4 weeks of starting chemotherapy (baseline), and 6 and 12 months after starting chemotherapy with dual-energy absorptiometry and markers of skeletal turnover osteocalcin and bone-specific alkaline phosphatase. Chemotherapy-induced

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Dobrokhotova, Iuliia E., Ekaterina I. Borovkova, Sofya A. Zalesskaya, Victoria S. Skalnaya, Ivan M. Borovkov, and Zulya S. Zaydieva. "Vitamin D3 and women's health." Gynecology 21, no. 1 (2019): 44–51. http://dx.doi.org/10.26442/20795696.2019.1.190235.

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Background. Vitamin D is an essential component that regulates calcium homeostasis and many other cellular functions. Hypovitaminosis D is associated with a risk of osteopenia, obesity, type 1 and type 2 diabetes, malignant neoplasms and immune disorders. Inadequate vitamin D intake during pregnancy increases a risk of pre-eclampsia, preterm birth, low birth weight as well as it has a negative impact on both children’s and adolescents’ health. It is important for the clinician to be known administrating of vitamin D prophylactic and therapeutic regimens according to serum 25(OH)D levels. Aim.

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Urban, Maria Letizia, Alessandra Bettiol, Irene Mattioli, et al. "Comparison of treatments for the prevention of fetal growth restriction in obstetric antiphospholipid syndrome: a systematic review and network meta-analysis." Internal and Emergency Medicine 16, no. 5 (2021): 1357–67. http://dx.doi.org/10.1007/s11739-020-02609-4.

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AbstractWomen with criteria and non-criteria obstetric antiphospholipid syndrome (APS) carry an increased risk of pregnancy complications, including fetal growth restriction (FGR). The management of obstetric APS traditionally involves clinicians, obstetricians and gynaecologists; however, the most appropriate prophylactic treatment strategy for FGR prevention in APS is still debated. We performed a systematic review and network meta-analysis (NetMA) to summarize current evidence on pharmacological treatments for the prevention of FGR in APS. We searched PubMed and Embase from inception until

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Lotfi, Asghar, Kobra Shiasi, Razieh Amini, et al. "Comparing the Effects of Two Feeding Methods on Metabolic Bone Disease in Newborns with Very Low Birth Weights." Global Journal of Health Science 8, no. 1 (2015): 249. http://dx.doi.org/10.5539/gjhs.v8n1p249.

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<p><strong>INTRODUCTION: </strong>Bone metabolic disease is an important issue in newborns with very low birth weight. The 80 percent of the transport of calcium (Ca) and phosphor (P) from mother to fetus takes place in the third trimester of pregnancy. This transport process is impaired with the preterm delivery of the newborn. On the other side, breast milk and formula are not competent resources to supply sufficient amounts of Ca and P to meet the requirements of the preterm newborn, thereby a greater reduction in the storage of these minerals. The current study has been d

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Cowchock, S. "Prevention of Fetal Death in the Antiphospholipid Antibody Syndrome." Lupus 5, no. 5 (1996): 467–72. http://dx.doi.org/10.1177/096120339600500528.

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The first treatment of pregnant women with antiphospholipid antibody syndrome (APLS) employed high doses of corticosteroids, plus low dose aspirin, with the goal of suppressing production of the autoantibody. Corticosteroids (usually prednisone), even when much lower doses are used, and even when tapered after midpregnancy, have been associated with significant maternal and obstetric risks and side effects: the most important are osteomalacia and preterm delivery (often precipitated by premature rupture of the membranes). Since the publication of a randomized trial demonstrating equivalent liv

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Faraji, Azam, Zahra Shomali, and Sedigeh Yoosefi. "Pregnancy-Associated Osteoporosis Presented with Femoral Neck Fracture: A Case Report and Literature Review." Galen Medical Journal 9 (December 26, 2020): 1750. http://dx.doi.org/10.31661/gmj.v9i0.1750.

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Background: Pregnancy-associated osteoporosis (PAO) is a rare condition characterized by reduced bone mineral density during the third trimester or lactation. Multiple risk factors, such as genetic, sedentariness, and 25-hydroxy vitamin D deficiency, are associated with PAO. In the majority of cases, PAO is presented with a compression fracture in vertebras, but in our case, it presented with a fracture of the femoral neck. Case Presentation: A 29-year-old, gravida one woman, developed right hip joint pain during the gestational age 34 weeks who referred to our clinic. Despite conservative man

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Junior, Antonio Carlos Cunha Lacreta, Washington Luiz Assunção Pereira, José Augusto Pereira Carneiro Muniz, Mariana Avelino de Souza Santos, Thâmira Mota, and Luthesco Haddad Lima Chalfun. "Bone Radiographic Changes in Slaughter Buffalos with Low Body Condition Index." Acta Scientiae Veterinariae 45, no. 1 (2017): 8. http://dx.doi.org/10.22456/1679-9216.80472.

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Background: The largest buffalo herd in Brazil is located on the Island of Marajó, in the State of Pará, northern Brazil. The pastures of the Island of Marajó consist of low quality graminaceous plants, which are generally poor in protein and mineral content. Unbalanced diets associated with low quality pastures are responsible for latent, sub-clinical diseases and metabolic disorders in bovines which affect bone health, especially in periods such as pregnancy and lactation. The purpose of this study was to point out and to describe the radiographic bone changes of buffalos with low body index

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Druzhinin, Valentin N., Vadim G. Suvorov, Aleksandr N. Cherniy, and Sergey N. Troinyakov. "Precision X-ray diagnosis of osteoporosis in representatives of risk groups for the appearance and development of varicose disease of the lower limbs." Russian Journal of Occupational Health and Industrial Ecology 60, no. 12 (2020): 911–17. http://dx.doi.org/10.31089/1026-9428-2020-60-12-911-917.

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Introduction. Varicose disease of the lower limbs (VDLL) is an independent disease and is an important medical and social problem due to its widespread and tendency to progress among people of working age and mainly in the female half of the population. Features of professional activity are risks in the form of static loads of a constant nature or weightlifting and other risk factors (for example, genetic predisposition, hormonal imbalance during pregnancy and menopause, obesity, diabetes mellitus, hypercoagulation, treatment with hormonal drugs, irrational nutrition, alcohol abuse, the presen

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Stojkoska, Ivana Mladenovska, Tatjana Milenkovic, Argjent Mucha, et al. "P-12 Postpartum vertebral compressive fractures in a young female with osteoporosis - A case report." JCEM Case Reports 2, Supplement_1 (2024). http://dx.doi.org/10.1210/jcemcr/luad146.017.

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Abstract Introduction Osteoporosis is а metabolic disorder characterized by low bone mass and deep changes in bone architecture that lead to an increased vertebral or hip fracture in elderly. Osteoporosis in young population is a very rare condition especially when is associated with compressive fractures. Pregnancy and postpartum-related osteoporosis is condition that occurs in the last trimester of pregnancy оr in the first months of lactation. It is self-limited condition that return to normal after 12-18 months. In rare cases leаds to spinal compressive fractures. Clinical Case We present

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Li, Xufeng, Hao Xiao, Zhixin Wu, Hui Wang, and Liaobin Chen. "The Increased Apoptosis of Mesenchymal Stem Cells Mediated Osteopenia Due to Prenatal Nicotine Exposure in Female Offspring Rats via IGF1 Pathway." Environmental Toxicology, August 29, 2024. http://dx.doi.org/10.1002/tox.24391.

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ABSTRACTNicotine exposure is a common adverse environment during pregnancy and causes developmental toxicity of long bones in offspring. However, the effect of prenatal nicotine exposure (PNE) on bone mass accumulation in female offspring and its mechanism remained to be further investigated. In this study, we constructed a PNE rat model and collected the long bone and the bone marrow mesenchymal stem cells (BMSCs) from female offspring rats for the detection of bone mass, cell apoptosis, and the expressions of osteogenesis‐ and apoptosis‐related genes. The results revealed that PNE induced lo

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Xia, Zhongyang, and Rizwan Rajak. "OA10 Pregnancy-associated osteoporosis - a rare subset of bone disease." Rheumatology Advances in Practice 7, Supplement_2 (2023). http://dx.doi.org/10.1093/rap/rkad070.010.

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Abstract Introduction Pregnancy-associated osteoporosis is a rare but serious condition in which patients present with fragility fractures (often vertebral) in the last trimester of pregnancy or the early postpartum period, generally in the first twelve weeks. The underlying pathological process is not yet clear – various causative mechanisms have been proposed, and it is possible that there is significant heterogeneity in aetiology. Research into this disease is limited by its rarity and diagnostic complexity, and at present there is no standard approach to management. It is essential to prom

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Ivanova, Margarita M., Julia Dao, Neil Kasaci, Fang Huang, Emily Nguyen, and Ozlem Goker-Alpan. "Age-related inflammatory biomarkers in early-onset osteoporosis in females with Gaucher disease." Frontiers in Endocrinology 16 (July 2, 2025). https://doi.org/10.3389/fendo.2025.1606218.

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Gaucher disease (GD), the most common lysosomal disorder, is caused by a deficiency of the enzyme glucocerebrosidase (GCase). Accumulation of the substrate, glycosylceramide (Gb-1), and its lysosomal derivative, glucosylsphingosine, Lyso-Gb1, are associated with immune-mediated inflammation. Patients with GD experience progressive bone disease, including early-onset osteoporosis (OSR). Bone marrow infiltration with Gaucher cells and reduced bone mineral density (BMD) suggest that glycosphingolipids affect hematopoiesis, osteoclast differentiation and activity. Unlike the general population, wh

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Kushwaha, Priyanka, Seva G. Khambadkone, Mengni Li, et al. "Maternal High-Fat Diet Induces Long-Lasting Defects in Bone Structure in Rat Offspring Through Enhanced Osteoclastogenesis." Calcified Tissue International, January 2, 2021. http://dx.doi.org/10.1007/s00223-020-00801-4.

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AbstractMaternal stressors during the prenatal and perinatal periods are associated with increased susceptibility for and severity of chronic disease phenotypes in adult offspring. In this study, we used a rat model of maternal high-fat diet (HFD) exposure during pregnancy and lactation to investigate the impact on skeletal homeostasis in offspring. In the distal femur, young male and female offspring (up to 3 weeks of age) from dams fed a HFD exhibited marked increases in trabecular bone volume relative to offspring from dams fed a chow diet, but this was followed by sustained bone loss. By 1

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Elbaz, Zeinab Mahmoud. "The Relationship between First Trimester 25-Hydroxyvitamin D3 Levels and Second Trimester Femur Length and their Effects on Birth Weight and Length at Birth." Austin Journal of Obstetrics and Gynecology 9, no. 1 (2022). http://dx.doi.org/10.26420/austiniobstetgynecol.2022.1199.

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Vitamin D is important for fetal development because of its important role during cell proliferation, differentiation, and maturation processes [1,2], also vitamin D is important for placental function, calcium homeostasis, and bone mineralization, which are all important determinants for fetal growth and development [3,4]. Primary source of vitamin D is the exposure to sunlight. Sedentary indoor lifestyles, obesity, and avoiding sunlight each contributes to increased vitamin D deficiency. A pregnant woman needs a daily intake of vitamin D of 800–1000 IU, but the actual need varies according t

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Shum, Betty J., Clement C. Cheung, and Anna Ryabets-Lienhard. "SAT-LB68 A Rare De Novo Mutation in LRP5 Gene in an Adolescent Female With Juvenile Onset Primary Osteoporosis." Journal of the Endocrine Society 4, Supplement_1 (2020). http://dx.doi.org/10.1210/jendso/bvaa046.2274.

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Abstract Background: Juvenile onset of primary osteoporosis is a rare skeletal disorder with a highly heterogenous clinical presentation and complex poorly understood genetic etiology. Low-density lipoprotein receptor-related protein 5 (LRP5), a Wnt-β-catenin pathway receptor involved in bone mineral density (BMD) regulation, has been reported in children with primary osteoporosis mainly due to missense and frame-shift mutations. To our knowledge, there is only one report of in-frame deletions in exon 21 possibly being implicated in pregnancy related osteoporosis (1). We report the first case

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Yoosefi, Sedigeh, Azam Faraji, and Zahra Shomali. "Pregnancy-Associated Osteoporosis Presented with Femoral Neck Fracture: A Case Report and Literature Review." Galen Medical Journal 9 (December 26, 2020). http://dx.doi.org/10.31661/gmj.v9i.1750.

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Background: Pregnancy-associated osteoporosis (PAO) is a rare condition characterized by reduced bone mineral density during the third trimester or lactation. Multiple risk factors, such as genetic, sedentariness, and 25-hydroxy vitamin D deficiency, are associated with PAO. In the majority of cases, PAO is presented with a compression fracture in vertebras, but in our case, it presented with a fracture of the femoral neck. Case Report: A 29-year-old, gravida one woman, developed right hip joint pain during the gestational age 34 weeks who referred to our clinic. Despite conservative managemen

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Zakharova, Anna, and Dmytro Govsieiev. "Determination of risk factors for osteopenic changes in women pregnant using assisted reproductive technologies." Bulletin of Medical and Biological Research, November 15, 2024, 60–68. https://doi.org/10.63341/bmbr/1.2025.60.

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The study aimed to investigate the factors that influence the risk of osteopenic changes in women who became pregnant with the help of assisted reproductive technologies. The study involved 150 women aged 25-40 who became pregnant after in vitro fertilisation, intrauterine insemination and oocyte donation. Bone mineral density was assessed by ultrasound densitometry in the distal forearm at the early (8-12 weeks) and late (32-36 weeks) stages of pregnancy. The T-score values showed a significant decrease in the third trimester in all groups, the largest – in patients who became pregnant due to

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