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Artykuły w czasopismach na temat „PVI threshold”

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Data publikacji: 3 czerwca 2025

Data aktualizacji: 19 lipca 2025

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1

Kohlmyer, S. G., R. M. Miyaoka, and T. K. Lewellen. "Evaluation of low energy threshold settings for PVI PET systems." IEEE Transactions on Nuclear Science 46, no. 6 (1999): 2141–45. http://dx.doi.org/10.1109/23.819296.

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z, Tolga, Hilal lu, Beng n, et al. "The Efficacy of Inferior Vena Cava Diameter, Perfusion Index and Pleth Variability Index on Predicting Hypotension in Spinal Anesthesia." Annals of Medical Research 29, no. 6 (2022): 1. http://dx.doi.org/10.5455/annalsmedres.2021.11.634.

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Objective: One of the most common side effects of spinal anesthesia (SA) is hypotension. The aim of the study was to evaluate the efficacay of inferior vena cava (IVC) diameter measurements, perfusion index (PI) and pleth variability index (PVI) values in determining the risk of developing hypotension after SA. Materials and Methods: This study was conducted on 81 patients who underwent transurethral prostatectomy. Before administration of SA, PI and PVI values, IVC diameters (IVCmin: during inspiration and IVCmax: during expiration) and IVC collapsibility index (IVCCI) values and non-invasive

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Bedi, Parvinder Singh, Bhavna Pahwa, Bhavna Hooda, and Deepak Dwivedi. "Plethysmographic variability index as a tool to assess fluid responsiveness in critically ill patients: a correlation study with inferior vena cava distensibility index." International Journal of Research in Medical Sciences 7, no. 12 (2019): 4663. http://dx.doi.org/10.18203/2320-6012.ijrms20195535.

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Background: In critically ill patients in the intensive care unit (ICU), early aggressive fluid replacement is the cornerstone of resuscitation. Traditionally employed static measures of fluid responsiveness have a poor predictive value. It is therefore imperative to employ dynamic measures of fluid responsiveness that take into account the heart lung interactions in the mechanically ventilated patients. The main objective of this study was to evaluate the reliability of one such non-invasive dynamic index: Plethysmographic variability index (PVI) compared to the widely employed Inferior vena

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Wenker, Steven, Chris van Lieshout, Geert Frederix, et al. "MRI-guided pulmonary vein isolation for atrial fibrillation: what is good enough? An early health technology assessment." Open Heart 6, no. 2 (2019): e001014. http://dx.doi.org/10.1136/openhrt-2019-001014.

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Next to anticoagulation, pulmonary vein isolation (PVI) is the most important interventional procedure in the treatment of atrial fibrillation (AF). Despite widespread clinical application of this therapy, patients often require multiple procedures to reach clinical success. In contrast to conventional imaging modalities, MRI allows direct visualisation of the ablation lesion. Therefore, the use of real-time MRI to guide cardiac electrophysiology procedures may increase clinical effectiveness. An essential aspect, from a decision-making point of view, is the effect on costs and the potential c

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Shapiro, Kenneth, Arno Fried, and Anthony Marmarou. "Biomechanical and hydrodynamic characterization of the hydrocephalic infant." Journal of Neurosurgery 63, no. 1 (1985): 69–75. http://dx.doi.org/10.3171/jns.1985.63.1.0069.

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✓ The pressure-volume index (PVI) technique of bolus manipulation of cerebrospinal fluid (CSF) was used to measure neural axis volume-buffering capacity and resistance to the absorption of CSF in 16 hydrocephalic infants prior to shunting. The mean steady-state intracranial pressure (ICP) was 11.7 ± 5.7 mm Hg (± standard deviation (SD)), representing a modest elevation of ICP in infants. The mean measured PVI was 28.1 ± 1.5 ml (± standard error of the mean (SEM)) compared to the predicted normal level for these infants of 12.1 ± 2.7 ml (± SD) (p < 0.001). This resulted from an enhanced volu

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MacMullin, Paul, Nathaniel Hodgson, Ugur Damar, et al. "Increase in Seizure Susceptibility After Repetitive Concussion Results from Oxidative Stress, Parvalbumin-Positive Interneuron Dysfunction and Biphasic Increases in Glutamate/GABA Ratio." Cerebral Cortex 30, no. 12 (2020): 6108–20. http://dx.doi.org/10.1093/cercor/bhaa157.

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Abstract Chronic symptoms indicating excess cortical excitability follow mild traumatic brain injury, particularly repetitive mild traumatic brain injury (rmTBI). Yet mechanisms underlying post-traumatic excitation/inhibition (E/I) ratio abnormalities may differ between the early and late post-traumatic phases. We therefore measured seizure threshold and cortical gamma-aminobutyric acid (GABA) and glutamate (Glu) concentrations, 1 and 6 weeks after rmTBI in mice. We also analyzed the structure of parvalbumin-positive interneurons (PVIs), their perineuronal nets (PNNs), and their electroencepha

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Shapiro, Kenneth, and Arno Fried. "Pressure-volume relationships in shunt-dependent childhood hydrocephalus." Journal of Neurosurgery 64, no. 3 (1986): 390–96. http://dx.doi.org/10.3171/jns.1986.64.3.0390.

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✓ The pressure-volume index (PVI) technique of bolus manipulation of cerebrospinal fluid (CSF) was used to measure neural axis volume buffering capacity and resistance to absorption of CSF (Ro) in 20 shunt-dependent hydrocephalic children acutely ill from shunt malfunction. All children had had ventricles that were near normal or subnormal in size when the shunts were functioning. The mean intracranial pressure (ICP, ± standard deviation (SD)) at the time of revision was 10.6 ± 6.4 mm Hg. The mean measured PVI (± standard error of the mean) was 18.4 ± 1.1 ml compared to the normal PVI of 17.5

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Gu, L., S. G. Pallardy, K. P. Hosman, and Y. Sun. "Predictors and mechanisms of the drought-influenced mortality of tree species along the isohydric to anisohydic continuum in a decade-long study of a central US temperate forest." Biogeosciences Discussions 12, no. 2 (2015): 1285–325. http://dx.doi.org/10.5194/bgd-12-1285-2015.

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Abstract. Using decade-long continuous observations of tree mortality and predawn leaf water potential (ψpd) at the Missouri Ozark AmeriFlux (MOFLUX) site, we studied how the mortality of important tree species varied along the isohydric to anisohydric continuum and how such variations may be predicted. Water stress determined inter-annual variations in tree mortality with a time delay of one year or more, which was predicted by predawn leaf water potential integral (PLWPI), mean effective precipitation interval (a time period with no daily precipitation rates exceeding a threshold) with a dai

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Driss, HADDOUCHE, MEDERBAL Khaladi, and SAIDI Slim. "Spatial entities and cover mapping by thresholding of a vegetation index: Case of the region of Naama (Algeria)." Agriculture and Forestry Journal 1, no. 1 (2017): 18–26. https://doi.org/10.5281/zenodo.810032.

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A large variety of methods and techniques for analyzing multidate satellite images have been developed to detect changes in the Earth's surface. Based on the assumption that changes in land use are reflected in changes in radiance, the preclassificatory method was used in this study, conducted on an arid steppe region belonging to the wilaya of Nama, West Algeria. This method consists in highlighting the radiometric changes between two images of Landsat (TM, 1987) and SpotView (XS, 2007) acquired on different dates but within the same annual period. The interpretation of the two maps derived b

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10

Dallaglio, Paolo D., Timothy R. Betts, Matthew Ginks, Yaver Bashir, Ignasi Anguera, and Kim Rajappan. "The Role of Adenosine in Pulmonary Vein Isolation: A Critical Review." Cardiology Research and Practice 2016 (2016): 1–13. http://dx.doi.org/10.1155/2016/8632509.

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The cornerstone of atrial fibrillation (AF) ablation is pulmonary vein isolation (PVI), which can be achieved in more than 95% of patients at the end of the procedure. However, AF recurrence rates remain high and are related to recovery of PV conduction. Adenosine testing is used to unmask dormant pulmonary vein conduction (DC). The aim of this study is to review the available literature addressing the role of adenosine testing and determine the impact of ablation at sites of PV reconnection on freedom from AF. Adenosine infusion, by restoring the excitability threshold, unmasks reversible inj

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Wang, Tien-Chin, and Bi-Chao Lee. "Community security is the key to sustainable governance: Methods and functions of crime hotspot predictions." Corporate Governance and Sustainability Review 5, no. 2 (2021): 57–72. http://dx.doi.org/10.22495/cgsrv5i2p5.

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Forecasting is becoming increasingly important in corporate sustainability governance, as is government governance, and the prediction of police crime hotspots is related to human rights, so transparency is needed. There are many ways to predict hotspots of criminal activity in urban areas. Experts assume that if many crimes occur somewhere, even more, are likely to happen at subsequent times. Such predictions may rely on a state dependency model such as the Poisson distribution algorithm to formulate re-occurrence, its results can provide a visualized hotspot map with Q-GIS maps. Forecasting

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Vedantam, Aditya, Jose-Miguel Yamal, Maria Laura Rubin, Claudia S. Robertson, and Shankar P. Gopinath. "Progressive hemorrhagic injury after severe traumatic brain injury: effect of hemoglobin transfusion thresholds." Journal of Neurosurgery 125, no. 5 (2016): 1229–34. http://dx.doi.org/10.3171/2015.11.jns151515.

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OBJECT There is limited literature available to guide transfusion practices for patients with severe traumatic brain injury (TBI). Recent studies have shown that maintaining a higher hemoglobin threshold after severe TBI offers no clinical benefit. The present study aimed to determine if a higher transfusion threshold was independently associated with an increased risk of progressive hemorrhagic injury (PHI), thereby contributing to higher rates of morbidity and mortality. METHODS The authors performed a secondary analysis of data obtained from a recently performed randomized clinical trial st

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Warren, Jared A., Oliver Scotting, Hiba K. Anis, et al. "ESR and CRP Diagnostic Thresholds for Prosthetic Joint Infection in Hip Hemiarthroplasty." Journal of Hip Surgery 4, no. 04 (2020): 187–92. http://dx.doi.org/10.1055/s-0040-1719115.

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AbstractDiagnostic thresholds used to standardize the definition for prosthetic joint infection (PJI) have largely focused on total joint arthroplasty (TJA). Established PJI thresholds exist for serum erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) in TJA; however, they do not exist for revision hip hemiarthroplasty (rHHA). The purpose of this study was to establish thresholds for (1) ESR and (2) CRP to diagnose PJI in rHHA. Data were collected on a prospective cohort of 69 rHHA patients undergoing orthopaedic surgery between 1/2017 and 2/2019 in a single health care system.

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Akinina, S. A. "PERIPROCEDURAL MYOCARDIAL DAMAGE." Cardiovascular Therapy and Prevention 12, no. 1 (2013): 95–101. http://dx.doi.org/10.15829/1728-8800-2013-1-95-101.

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Percutaneous coronary intervention (PCI), as a method of myocardial revascularisation, is widely and effectively used for the treatment of coronary heart disease (CHD), with immediate success rates of >90%. Depending on the diagnostic criteria, 5–30% of these patients could develop the signs of periprocedural myocardial damage (PMD) or periprocedural myocardial infarction (PMI). PMD predictors, mechanisms of PMD development, and its specific clinical features play an important role in the PMI prevention. At present, there is no universal agreement on the definition and diagnostics of peripr

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Yang, Chia-Hsiang, and Uwe Soergel. "ADAPTIVE 4D PSI-BASED CHANGE DETECTION." ISPRS Annals of Photogrammetry, Remote Sensing and Spatial Information Sciences IV-3 (April 23, 2018): 245–50. http://dx.doi.org/10.5194/isprs-annals-iv-3-245-2018.

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In a previous work, we proposed a PSI-based 4D change detection to detect disappearing and emerging PS points (3D) along with their occurrence dates (1D). Such change points are usually caused by anthropic events, e.g., building constructions in cities. This method first divides an entire SAR image stack into several subsets by a set of break dates. The PS points, which are selected based on their temporal coherences before or after a break date, are regarded as change candidates. Change points are then extracted from these candidates according to their change indices, which are modelled from

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Bulluck, Heerajnarain, Valeria Paradies, Emanuele Barbato, et al. "Prognostically relevant periprocedural myocardial injury and infarction associated with percutaneous coronary interventions: a Consensus Document of the ESC Working Group on Cellular Biology of the Heart and European Association of Percutaneous Cardiovascular Interventions (EAPCI)." European Heart Journal 42, no. 27 (2021): 2630–42. http://dx.doi.org/10.1093/eurheartj/ehab271.

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Abstract A substantial number of chronic coronary syndrome (CCS) patients undergoing percutaneous coronary intervention (PCI) experience periprocedural myocardial injury or infarction. Accurate diagnosis of these PCI-related complications is required to guide further management given that their occurrence may be associated with increased risk of major adverse cardiac events (MACE). Due to lack of scientific data, the cut-off thresholds of post-PCI cardiac troponin (cTn) elevation used for defining periprocedural myocardial injury and infarction, have been selected based on expert consensus opi

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Walling, Donovan R. "Phi Delta Kappa at the Threshold." Phi Delta Kappan 87, no. 5 (2006): K1—K8. http://dx.doi.org/10.1177/003172170608700520.

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Li, Chengming, Li Liu, Zhaoxin Dai, and Xiaoli Liu. "Different Sourcing Point of Interest Matching Method Considering Multiple Constraints." ISPRS International Journal of Geo-Information 9, no. 4 (2020): 214. http://dx.doi.org/10.3390/ijgi9040214.

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Point of interest (POI) matching is critical but is the most technically difficult part of multi-source POI fusion. The accurate matching of POIs from different sources is important for the effective reuse of POI data. However, the existing research on POI matching usually adopts weak constraints, which leads to a low POI matching accuracy. To address the shortcomings of previous studies, this paper proposes a POI matching method with multiple determination constraints. First, according to various attributes (name, class, and spatial location), a new calculation model considering spatial topol

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Zhang, Mingxing, Ye Zhang, Yuhong Bian, Hui Fu, Ying Xu, and Yi Guo. "Effect of Long-Term Electroacupuncture Stimulation on Recovery of Sensorimotor Function after Peripheral Nerve Anastomosis." Acupuncture in Medicine 36, no. 3 (2018): 170–75. http://dx.doi.org/10.1136/acupmed-2017-011367.

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Background Recently, application of electroacupuncture (EA) to stimulate nerve regeneration has become a mainstream treatment in clinical rehabilitation and related basic research, but the efficacy of long-term stimulation has not been confirmed. Objective To evaluate the influence of long term EA on peripheral nerve injury (PNI) from multiple angles. Method Twenty-four rats were divided into three groups: control, PNI and PNI+EA. In the latter two groups, PNI was modelled by transection followed by re-anastomosis of thesciatic nerve. In the PNI+EA group only, EA was delivered using a disconti

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RYU, HUIYOUNG, ATSUSHI HOSAKA, HYUN-CHUL KIM, and A. I. TITOV. "PHOTOPRODUCTION OF PHI MESON NEAR THE THRESHOLD." International Journal of Modern Physics: Conference Series 26 (January 2014): 1460055. http://dx.doi.org/10.1142/s2010194514600556.

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Photoproduction of ϕ, γp → ϕ + p, is revisited in a model with Pomeron and hadron degrees of freedom. The scattering equation is written such that the final state interaction is included at the one-loop level of hadrons. We find a parameter set to reproduce the bump-like structure near the threshold in a way consistent with other meson production data.

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Shinneeb, A.-M., J. D. Bugg, and R. Balachandar. "Variable threshold outlier identification in PIV data." Measurement Science and Technology 15, no. 9 (2004): 1722–32. http://dx.doi.org/10.1088/0957-0233/15/9/008.

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Ahmed, Y. K., and A. R. Zubair. "Performance Evaluation of Wavelet De-Noising Schemes for Suppression of Power Line Noise in Electrocardiogram Signals." Nigerian Journal of Technological Development 18, no. 2 (2021): 144–51. http://dx.doi.org/10.4314/njtd.v18i2.9.

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Power line noise introduces distortions to recorded electrocardiogram (ECG) signals. These distortions compromise the integrity and negatively affect the interpretation of the ECG signals. Despite the fact that the amplifiers used in biomedical signal processing have high common mode rejection ratio (CMRR), ECG recordings are still often corrupted with residual Power Line Interference (PLI) noise. Further improvement in the hardware solutions do not have significant achievements in PLI noise suppression but rather introduce other adverse effects. Software approach is necessary to refine ECG da

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Rankinen, Tuomo, Sari Väisänen, llkka Penttilä, and Rainer Rauramaa. "Acute Dynamic Exercise Increases Fibrinolytic Activity." Thrombosis and Haemostasis 73, no. 02 (1995): 281–86. http://dx.doi.org/10.1055/s-0038-1653765.

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SummaryThe influence of acute bouts of dynamic exercise on plasma tissue plasminogen activator (tPA), plasminogen activator inhibitor (PAI) and fibrinogen was investigated on nine healthy non-smoking men aged 23 to 37 years. Subjects performed maximal and two submaximal (duration 30 min, intensity 50% [aerobic threshold] and 78% [anaerobic threshold] V02max) bicycle ergospirometry tests separated by seven days. The order of the submaximal tests was randomized. Blood samples were drawn before, immediately after and 24 h after each test. Plasma tPA and PAI activities were measured amidolytically

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Wisniewski, Konrad, Giovanni Concistrè, and Angelo Maria Dell’Aquila. "Unplanned Postoperative Angiography After Isolated Coronary Artery Bypass Grafting: State of the Art and Future Perspective." Medicina 61, no. 7 (2025): 1241. https://doi.org/10.3390/medicina61071241.

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Unplanned postoperative coronary angiography (uCAG) following isolated coronary artery bypass grafting (CABG) represents a significant clinical challenge, reflecting postoperative myocardial ischemia (PMI) with substantial impact on outcomes. The incidence of uCAG varies from 0.39 to 5.3%, depending on institutional protocols and diagnostic thresholds. Elevated cardiac biomarkers (high-sensitivity troponin and CK-MB), ECG changes, and hemodynamic instability are key indicators guiding uCAG. While associated with increased short-term mortality and morbidity, timely identification and treatment

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Boyarsky, G., N. Rosenthal, E. Barrett, and W. F. Boron. "Effect of diabetes on Na(+)-H+ exchange by single isolated hepatocytes." American Journal of Physiology-Cell Physiology 260, no. 1 (1991): C167—C175. http://dx.doi.org/10.1152/ajpcell.1991.260.1.c167.

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We used the fluorescent dye 2',7'-bis-(2-carboxyethyl)-5(6)-carboxyfluorescein (BCECF) to examine intracellular pH (pHi) regulation in single hepatocytes isolated from control rats and rats with either spontaneous or drug-induced diabetes mellitus (DM). In the absence of CO2-HCO3-, both control and DM cells recovered from cellular acid loads applied by the NH4+ prepulse technique. Because the pHi recovery was blocked by either Na+ withdrawal or ethylisopropylamiloride in both control and DM cells, it was presumably mediated by Na(+)-H+ exchange. In the control cells, the pHi threshold above wh

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Zhang, Guoping, Shuai Xing, Qing Xu, Pengcheng Li, and Dandi Wang. "A Pre-Pruning Quadtree Isolation Method with Changing Threshold for ICESat-2 Bathymetric Photon Extraction." Remote Sensing 15, no. 6 (2023): 1629. http://dx.doi.org/10.3390/rs15061629.

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The new generation of spaceborne laser altimeter, the Ice, Cloud, and Land Elevation Satellite-2 (ICESat-2), which can simultaneously generate laser reflections on the water surface and underwater, is a potential data source for exploring water depth in nearshore environments. To achieve this scientific goal, accurate bathymetric photon extraction is needed. This study proposed a pre-pruning quadtree isolation (PQI) method with changing threshold. Firstly, the pre-pruning step is introduced. Photons are transformed into different levels in the isolated quadtree structure according to spatial d

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Sieving, P. A., L. J. Frishman, and R. H. Steinberg. "Scotopic threshold response of proximal retina in cat." Journal of Neurophysiology 56, no. 4 (1986): 1049–61. http://dx.doi.org/10.1152/jn.1986.56.4.1049.

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We describe a new response in proximal retina of cat that is present under scotopic conditions, clearly differs from PII (b-wave and DC component) and contributes a negative potential at threshold to the diffuse electroretinogram (ERG). We have termed this response the scotopic threshold response (STR). Extracellular potentials evoked in response to circular spots of light at dark-adapted threshold, and with dim backgrounds, were recorded with microelectrodes placed intraretinally at different depths. The dark-adapted response of proximal retina (STR) consisted of a graded negative potential t

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Sukri, Mhd Alfahjri. "Analisis Perbandingan Kepentingan PDIP dan Partai Demokrat dalam Menyikapi Presidential Threshold." JRP (Jurnal Review Politik) 13, no. 1 (2023): 152–78. http://dx.doi.org/10.15642/jrp.2023.13.1.152-178.

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This study aims to analyze by comparing the political interests of the PDI-P and the Democratic Party in addressing the presidential threshold (PT). The research uses a qualitative method with data sourced from the results of DPR meetings, books, journals and news. The research finding is that the PDI-P and the Democratic Party have a political interest in addressing the presidential threshold. When in power, the Democrat Party initially shared the same view as the PDI-P in supporting PT at least 20-25 percent. However, this attitude changed when the Democratic Party was no longer in power and

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Ashikaga, Hiroshi, Jonathan Chrispin, Degang Wu, and Joshua Garland. "Abstract 17426: Pulmonary Vein Isolation ‘Rewires’ Electrical Communications to Enhance Small-world Network Topology During Atrial Fibrillation." Circulation 132, suppl_3 (2015). http://dx.doi.org/10.1161/circ.132.suppl_3.17426.

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Recent evidence suggests that pulmonary vein isolation (PVI) may perturb the electrophysiological substrate for maintenance of atrial fibrillation (AF). Our previous work indicates that information theory metrics can quantify electrical communications during arrhythmia. We hypothesized that PVI ‘rewires’ the electrical communication network during AF such that the topology exhibits higher levels of small-world network properties, with higher clustering coefficient and lower path length, than would be expected by chance. Thirteen consecutive patients (n=6 with prior PVI and n=7 without) underwe

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Hermans, B. J. M., F. I. P. Farnir, G. P. Bijvoet, et al. "Optimal image intensity ratio threshold for atrial focal monopolar pulsed field ablation lesions assessment by dark-blood late gadolinium enhancement cardiac magnetic resonance imaging." Europace 27, Supplement_1 (2025). https://doi.org/10.1093/europace/euaf085.388.

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Abstract Background Dark-blood late gadolinium enhancement cardiac magnetic resonance imaging (LGE CMR) has been used to assess ablation lesions after pulmonary vein isolation (PVI) by thermal energy sources (cryo and radiofrequency) with an optimal image intensity ratio (IIR) threshold of 1.09. However, the performance of dark-blood LGE MRI in assessing ablation lesions after PVI by monopolar biphasic focal pulsed field ablation (F-PFA) remains unclear. Purpose To determine the optimal IIR threshold for assessing F-PFA PVI lesions in dark-blood LGE MRI scans. Methods In eighteen patients, a 3

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Bijvoet, G. P., B. J. M. Hermans, R. J. Holtackers, et al. "The use of novel 3D dark-blood late gadolinium enhancement MRI to determine the optimal threshold for atrial scar after pulmonary vein isolation ablation." European Heart Journal 43, Supplement_2 (2022). http://dx.doi.org/10.1093/eurheartj/ehac544.421.

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Abstract Background Dark-blood late gadolinium enhancement (LGE) magnetic resonance imaging (MRI) is proved to be superior to bright-blood LGE MRI in localising subtle subendocardial scar in the ventricles, because of improved contrast between myocardial scar and blood. However, dark-blood LGE MRI has not yet been applied to identify atrial scar in the left atrium (LA) and therefore its threshold to determine scar is unknown. Purpose To determine the optimal intensity threshold for 3D dark-blood LGE MRI for atrial ablation scar after pulmonary vein isolation (PVI) Methods Twelve re-do PVI pati

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Pitoulias, Apostolos G., Nefeli Andrioti Petropoulou, Vangelis Bontinis, et al. "Ultrasonography in the diagnosis of pelvic vein insufficiency, a systematic review and meta-analysis." Phlebology: The Journal of Venous Disease, January 4, 2025. https://doi.org/10.1177/02683555241312780.

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Objective To perform a systematic review and meta-analysis to investigate the efficacy of ultrasonography in the diagnosis of pelvic vein insufficiency (PVI). Results Seven studies comprised of 802 patients were included. Of these studies, 5 utilised transvaginal ultrasound (TVU), 1 utilised transabdominal ultrasound (TAU) and 1 utilised both ultrasounds as diagnostic tool .The overall pooled sensitivity and specificity was 0.96 and 0.84 respectively. The sensitivity and specificity for TVU were 0.96 and 0.86. The pooled sensitivities between studies employing a <7 mm cutoff in pelvic veins

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Phkhaladze, K., H. Omran, T. Fink, et al. "A new stepwise approach to minimize phrenic nerve injury during cryoballoon pulmonary vein isolation." Journal of Interventional Cardiac Electrophysiology, December 20, 2024. https://doi.org/10.1007/s10840-024-01953-1.

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Abstract Background A phrenic nerve injury (PNI) during cryoballoon (CB) pulmonary vein isolation (PVI) continues to represent a limitation of this technique. The objective of this study was to develop a novel technique with the aim of reducing the incidence of PNI. Methods We performed a retrospective analysis of data from two hospitals in patients with symptomatic, drug-resistant atrial fibrillation (AF) over 7 years to evaluate the incidence and clinical characteristics of PNI during cryoballoon PVI. Patients in the intervention group were treated with a new technique consisting of the foll

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Cheung, Christopher C., Michael Ferguson, Louise H. Anderson, et al. "Abstract 10920: Cost-Effectiveness of Pulmonary Vein Isolation with Epicardial Left Atrial Appendage Ligation for the Treatment of Non-Paroxysmal Atrial Fibrillation." Circulation 144, Suppl_1 (2021). http://dx.doi.org/10.1161/circ.144.suppl_1.10920.

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Introduction: Electrical isolation of the left atrial appendage (LAA) using percutaneous epicardial ligation may improve catheter ablation outcomes for non-paroxysmal atrial fibrillation (AF) patients. Little is known regarding the cost effectiveness of this procedure. Hypothesis: We hypothesized that cost-effectiveness between pulmonary vein isolation (PVI) + LAA epicardial ligation using a percutaneous LARIAT ® Suture Delivery Device would be cost effective (CE) compared to PVI alone over 5 years. Methods: A Markov model simulated outcomes for a population with annual stroke risk of 4.6% (CH

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Roney, C., J. S. L. Alonso, I. Sim, et al. "In silico biatrial fibrosis ablation improves atrial fibrillation outcome." Europace 25, Supplement_1 (2023). http://dx.doi.org/10.1093/europace/euad122.587.

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Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Medical Research Council Fellowship Background In DECAAF II, left atrial (LA) fibrosis ablation plus PVI did not improve AF outcome compared to PVI alone across the study cohort. We hypothesize that biatrial fibrosis ablation could improve AF ablation therapy outcome in a subset of patients with properties identified through a large virtual in silico trial. Purpose To investigate the effects of anatomy, fibrosis distribution, and LGE-MRI threshold on ablation outcome using

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Sato, Taiki, Yohei Sotomi, Shungo Hikoso, et al. "Uplift modeling to identify patients who require extensive catheter ablation procedures among patients with persistent atrial fibrillation." Scientific Reports 14, no. 1 (2024). http://dx.doi.org/10.1038/s41598-024-52976-7.

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AbstractIdentifying patients who would benefit from extensive catheter ablation along with pulmonary vein isolation (PVI) among those with persistent atrial fibrillation (AF) has been a subject of controversy. The objective of this study was to apply uplift modeling, a machine learning method for analyzing individual causal effect, to identify such patients in the EARNEST-PVI trial, a randomized trial in patients with persistent AF. We developed 16 uplift models using different machine learning algorithms, and determined that the best performing model was adaptive boosting using Qini coefficie

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Phkhaladze, K., H. Omran, J. Thale, et al. "Novel technique for significant reduction of phrenic nerve injury in cryoballoon pulmonary vein isolation." European Heart Journal 44, Supplement_2 (2023). http://dx.doi.org/10.1093/eurheartj/ehad655.521.

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Abstract Background/Introduction Pulmonary vein isolation (PVI) in cryoballoon (CB) technique is a golden standard for AF treatment. However, collateral damage of non-cardiac structures, such as phrenic nerve injury (PNI) remains an Achille’s heel of CB technology. Purpose The purpose of this study was to develop a therapeutic concept while establishing a new technique with three consecutive steps during the procedure in order to significantly decrease the occurrence of PNI in the intervention group in comparison with control group. Methods We conducted a retrospective, multicenter, observatio

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Bhatt, Daxina, Shaneel Patel, David Riding, et al. "Accuracy of transvaginal duplex ultrasound compared to catheter venography for the identification of pelvic vein incompetence." Phlebology: The Journal of Venous Disease, June 19, 2025. https://doi.org/10.1177/02683555251353550.

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Objective Chronic pelvic pain (CPP) is a debilitating condition affecting a quarter of premenopausal women and has been associated with pelvic vein incompetence (PVI). Catheter venography (CV) is the standard investigation, although transvaginal duplex (TVDU) ultrasound has emerged as a promising alternative. The accuracy of TVDU compared to CV is undefined and the optimal reflux time measured by TVDU to diagnose PVI is unknown. This study aimed to establish the diagnostic accuracy of TVDU in those with suspected PVI. Methods This cohort study included women enrolled into a randomised controll

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Aboelnile, Diaaeldin Badr Metwally Kotb, Mohamed Ismail Abdelfattah Elseidy, Yasir Ahmed Elbasiony Mohamed Kenawey, and Ibrahim Mohammed Alsayed Ahmed Elsherif. "Prediction of fluid responsiveness in mechanically ventilated patients in surgical intensive care unit by pleth variability index and inferior vena cava diameter." Ain-Shams Journal of Anesthesiology 12, no. 1 (2020). http://dx.doi.org/10.1186/s42077-020-00097-4.

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Abstract Background Patients may have signs of hypovolemia, but fluid administration is not always beneficial. We are in need of bedside devices and techniques, which can predict fluid responsiveness effectively and safely. This study is aiming to compare the effectiveness and reliability of the pleth variability index (PVI) and IVC distensibility index (dIVC) as predictors of fluid responsiveness by simultaneous recordings in all sedated mechanically ventilated patients in the surgical intensive care unit (ICU). We used the passive leg raising test (PLR) as a harmless reversible technique for

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Nairn, D., C. Nagel, B. Mueller-Edenborn, H. Lehrmann, A. Jadidi, and A. Loewe. "Spatial and quantitative assessment of the correlation between sinus rhythm and atrial fibrillation voltage mapping to identify low voltage substrate in persistent atrial fibrillation." EP Europace 23, Supplement_3 (2021). http://dx.doi.org/10.1093/europace/euab116.163.

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Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Deutsche Forschungsgemeinschaft (DFG) through DO637/22-3 Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg through the Research Seed Capital (RiSC) program. Introduction Presence of left atrial (LA) fibrotic low voltage substrate (LVS) is associated with high risk for arrhythmia recurrences in patients undergoing pulmonary vein isolation (PVI) for atrial fibrillation (AF). PVI and additional ablation of LVS - as identified by mapping in sinus rhythm (SR)

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Keane, Stephen, Darshak Patel, Brian Otto, et al. "Incidental ablation of ganglionated plexus during atrial fibrillation ablation." Journal of Interventional Cardiac Electrophysiology, July 27, 2024. http://dx.doi.org/10.1007/s10840-024-01886-9.

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Abstract Background Cardioneuroablation targeting the autonomic nerves within ganglionated plexus (GP) has been used to treat atrial fibrillation (AF). Incidental cardioneuroablation may be an important mechanism by which pulmonary vein isolation (PVI) is effective. Automated fractionation mapping software can identify regions of fractionation correlating with GP locations. Objective To examine the overlap between standard PVI ablation lesions and fractionated electrograms suggestive of GP. Methods We retrospectively examined AF ablations performed from 2021 to 2023 that included only PVI perf

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Winkelmann, SJ, MD Lemoine, T. Wuerger, et al. "Safety of pulsed-field ablation in patients with cardiac implantable electronic devices. A single-center pilot study." EP Europace 24, Supplement_1 (2022). http://dx.doi.org/10.1093/europace/euac053.234.

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Abstract Funding Acknowledgements Type of funding sources: None. Introduction Pulsed-field ablation (PFA) is a novel energy source to perform pulmonary vein isolation (PVI) in patients with atrial fibrillation or cavo-tricuspid isthmus ablation (CTI) in patients with atrial flutter. Whether strong electrical fields generated by PFA could change the function and integrity of cardiac implantable electronic devices (CIED) is not known. Aim To assess the function and integrity of implanted devices before and after pulsed-field ablation. Methods This study included consecutive patients with CIED un

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Chen, Yu, and Qiang Hu. "Observations of Small‐Scale Magnetic Flux Ropes Associated With Significant Values of Partial Variance Increment Indices." Journal of Geophysical Research: Space Physics 130, no. 1 (2025). https://doi.org/10.1029/2024ja033130.

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AbstractWe report recent findings for the magnetic field configurations of small‐scale magnetic flux ropes (SFRs) broadly defined and identified by using the Grad‐Shafranov‐based techniques for in situ measurements via the Parker Solar Probe (PSP), Solar Orbiter (SolO), and two Helios spacecraft. Since the current sheets were found to occur at boundaries of SFRs and/or inside SFRs at 1 AU via the partial variance increment (PVI) and the Grad‐Shafranov (GS) reconstruction technique by Pecora et al. (2019), https://doi.org/10.3847/2041‐8213/ab32d9, we further examine such a co‐existence in this

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Althoff, Till F., Eichenlaub Martin, David Padilla-Cueto, et al. "Predictive value of late gadolinium enhancement cardiovascular magnetic resonance in patients with persistent atrial fibrillation – dual center validation of a standardised method." European Heart Journal Open, December 29, 2022. http://dx.doi.org/10.1093/ehjopen/oeac085.

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Abstract Aims With recurrence rates up to 50% after pulmonary vein isolation (PVI) in persistent atrial fibrillation (AF), predictive tools to improve patient selection are needed. Patient selection based on left atrial late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) has been proposed previously (UTAH-classification). However, this approach has not been widely established, in part owed to the lack of standardization of the LGE quantification method. We have recently established a standardised LGE-CMR method enabling reproducible LGE-quantification. Here, the ability o

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Eichenlaub, M., H. Lehrmann, J. Minners, et al. "Comparison of various tools for diagnosis of an atrial cardiomyopathy for outcome prediction after pulmonary vein isolation in patients with persistent atrial fibrillation - What is the Holy Grail?" Europace 25, Supplement_1 (2023). http://dx.doi.org/10.1093/europace/euad122.645.

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Abstract Funding Acknowledgements Type of funding sources: Private company. Main funding source(s): Medtronic Background Atrial cardiomyopathy (ACM) is associated with an increased risk for new-onset atrial fibrillation (AF), progression from paroxysmal to persistent AF-forms and higher arrhythmia recurrence rates after PVI. Therefore, the current ESC guidelines on AF recommend to characterize the underlying ACM to better inform and treat AF patients. Over the past decade, various diagnostic tools were established to diagnose an ACM by analyzing left atrial (LA) structure, and LA electrical an

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Chaves, Renato Carneiro de Freitas, Carmen Silvia Valente Barbas, Veronica Neves Fialho Queiroz, et al. "Assessment of fluid responsiveness using pulse pressure variation, stroke volume variation, plethysmographic variability index, central venous pressure, and inferior vena cava variation in patients undergoing mechanical ventilation: a systematic review and meta-analysis." Critical Care 28, no. 1 (2024). http://dx.doi.org/10.1186/s13054-024-05078-9.

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Abstract Importance Maneuvers assessing fluid responsiveness before an intravascular volume expansion may limit useless fluid administration, which in turn may improve outcomes. Objective To describe maneuvers for assessing fluid responsiveness in mechanically ventilated patients. Registration The protocol was registered at PROSPERO: CRD42019146781. Information sources and search PubMed, EMBASE, CINAHL, SCOPUS, and Web of Science were search from inception to 08/08/2023. Study selection and data collection Prospective and intervention studies were selected. Statistical analysis Data for each m

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Bruss, J., T. Kueffer, G. Thalmann, et al. "NT-proBNP as a predictor of successful pulmonary vein isolation using pulsed-field, cryoballoon or radiofrequency ablation." Europace 27, Supplement_1 (2025). https://doi.org/10.1093/europace/euaf085.451.

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Abstract Background B-Type natriuretic peptide (NT-proBNP) is recognized as a biomarker for atrial disease as well as a predictor for the success of pulmonary vein isolation (PVI). In recent years pulsed-field ablation (PFA) has emerged as a novel technology for performing PVI. Purpose Previous studies have shown a correlation between NT-proBNP levels and atrial fibrillation recurrence following PVI using radiofrequency ablation (RFA) and cryoballoon ablation (CBA). This study aims to investigate whether NT-proBNP can also serve as a reliable predictor for successful PVI using pulsed-field abl

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Eichenlaub, Martin, Bjoern Mueller-Edenborn, Jan Minners, et al. "Echocardiographic diagnosis of atrial cardiomyopathy allows outcome prediction following pulmonary vein isolation." Clinical Research in Cardiology, April 29, 2021. http://dx.doi.org/10.1007/s00392-021-01850-x.

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Abstract Background Relevant atrial cardiomyopathy (ACM), defined as a left atrial (LA) low-voltage area ≥ 2 cm2 at 0.5 mV threshold on endocardial contact mapping, is associated with new-onset atrial fibrillation (AF), higher arrhythmia recurrence rates after pulmonary vein isolation (PVI), and an increased risk of stroke. The current study aimed to assess two non-invasive echocardiographic parameters, LA emptying fraction (EF) and LA longitudinal strain (LAS, during reservoir (LASr), conduit (LAScd) and contraction phase (LASct)) for the diagnosis of ACM and prediction of arrhythmia outcome

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Kueffer, Thomas, Ajay Panakal, Claudia Herrera, et al. "Voltage threshold adjustments for a novel pulsed-field ablation catheter with integrated mapping capabilities – lessons from a case series." European Heart Journal - Case Reports, May 12, 2025. https://doi.org/10.1093/ehjcr/ytaf231.

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Abstract Background Accurate electroanatomical mapping relies on voltage thresholds to differentiate electrically inactive areas, fibrotic scar, and healthy myocardium. These thresholds have been well established for high-density mapping catheters with small, closely spaced electrodes. However, the optimal voltage thresholds for a novel pulsed field ablation (PFA) catheter with integrated mapping capabilities remain unclear. This case series evaluates different voltage thresholds for the variable-loop circular catheter (VLCC, Varipulse, Biosense Webster) compared to a dedicated high-density ma

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Huber, Adrian Thomas, Severin Fankhauser, Severin Wittmer, et al. "Epicardial adipose tissue dispersion at CT and recurrent atrial fibrillation after pulmonary vein isolation." European Radiology, January 10, 2024. http://dx.doi.org/10.1007/s00330-023-10498-2.

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Abstract Objectives Epicardial adipose tissue (EAT) remodeling is associated with atrial fibrillation (AF). Left atrial (LA) EAT dispersion on cardiac CT is a non-invasive imaging biomarker reflecting EAT heterogeneity. We aimed to investigate the association of LA EAT dispersion with AF recurrence after pulmonary vein isolation (PVI). Methods In a prospective registry of consecutive patients undergoing first PVI, mean EAT attenuation values were measured on contrast-enhanced cardiac CT scans in Hounsfield units (HU) within low (− 195 to − 45 HU) and high (− 44 to − 15 HU) threshold EAT compar

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