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Gotowe bibliografie tematyczne / PVPK-30

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Artykuły w czasopismach

Gotowa bibliografia na temat „PVPK-30”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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Artykuły w czasopismach na temat "PVPK-30"

1

Patil, Monali, Swati Waydande, and Pravin Pawar. "Design and evaluation of topical solid dispersion composite of voriconazole for the treatment of ocular keratitis." Therapeutic Delivery 10, no. 8 (2019): 481–92. http://dx.doi.org/10.4155/tde-2019-0021.

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Aim: The objective of present investigation was to increases solubility of voriconazole by using solid dispersion techniques and the development of solid dispersion-based voriconazole ophthalmic solutions. Materials & methods: The saturation solubility of solid dispersion containing polyvinylpyrrolidone K90 (PVPK-90) was found to increase the solubility of voriconazole compare other carrier like polyethylene glycol and Polyvinylpyrrolidone K 30 (PVPK-30). Solid dispersion of voriconazole was characterized by saturation solubility, Fourier-transform infrared spectroscopy and Differential sc

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2

M., Lavanya* and A. Deevan Paul. "IMPROVEMENT OF SOLUBILITY OF CEFIXIME AND OMEPRAZOLE BY SOLID DISPERSION AND SLUGGING METHOD." Indo American Journal of Pharmaceutical Sciences 04, no. 07 (2017): 2036–41. https://doi.org/10.5281/zenodo.834616.

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In fact, it has been estimated that 40% of new chemical entities currently being discovered are poorly watersoluble. Unfortunately, many of these potential drugs area bandoned in the early stages of development due to solubility concerns. Cefixime as per BCS classification is a class IV drug with poor solubility and poor permeability. Poor solubility of drugs leads to poor absorption and hence poor bioavailability. Omeprazole as per BCS classification is a class II drug with poor solubility and good permeability. Methods, such as salt formation, complexation with cyclodextrins, solubilization

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3

Raturi, Ankita, Ganesh Bhatt, and Preeti Kothiyal. "FORMULATION AND EVALUATION OF NANOSUSPENSION OF ROSUVASTATIN CALCIUM." International Journal of Drug Regulatory Affairs 1, no. 3 (2018): 14–18. http://dx.doi.org/10.22270/ijdra.v1i3.115.

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Poor water solubility and slow dissolution rate are issues for majority of upcoming and existing biologically active compounds. The aim of present work was to increase the dissolution rate of Rosuvastatin Calcium, a poorly water soluble drug and hence improve its oral bioavailability by Nanosuspension technology. Nanosuspension is new carrier free colloidal drug delivery system with nano sized particles below 1000 nm, and considered as a great drug delivery technique to enhance the drug dissolution and solubility. In the present work Nanosuspension is made by nanoprecipitation technique in the

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4

Rao, Y. Madhusudan, Sunil Reddy, Panakanti Pavan Kumar, and Rajanarayana Kandagatla. "Formulation and Release Characteristic of a Bilayer Matrix Tablet Containing Glimepride Immediate Release Component and Metformin Hydrochloride as Sustained Release Component." International Journal of Pharmaceutical Sciences and Nanotechnology 3, no. 1 (2010): 851–59. http://dx.doi.org/10.37285/ijpsn.2010.3.1.8.

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The aim of present study was to design the concept of bilayered tablets containing Glimepride for immediate release using sodium starch glycolate as super disintegrant and Metformin hydrochloride (HCl) for sustained release by using Hydroxyl propyl methyl cellulose (HPMC K 4M) and Sodium Carboxy Methyl cellulose (SCMC) as the matrix forming polymer, and PVPK-30 as binder. The tablets were evaluated for physicochemical properties. All the values were found to be satisfactory. In vitro release studies were carried out as per USP in pH 1.2 with (0.1% sodium lauryl sulphate w/v) and phosphate buff

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5

A.Ali, Yasser, and Shaimaa N. Abd-Alhammid. "Formulation and Evaluation of Ezetimibe Nanoparticles." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512) 24, no. 2 (2017): 11–21. http://dx.doi.org/10.31351/vol24iss2pp11-21.

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The aim of this study is to formulate and evaluate ezetimibe nanoparticles using solvent antisolvent technology. Ezetimibe is a practically water-insoluble drug which acts as a lipid lowering drug that selectively inhibits the intestinal absorption of cholesterol and related phytosterols. Ezetimibe prepared as nano particles in order to improve its solubility and dissolution rate. Thirty formulas were prepared and different stabilizing agents were used with different concentrations such as poly vinyl pyrrolidone (PVPK-30), poly vinyl alcohol (PVA), hydroxy propyl methyl cellulose E5 (HPM

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6

Shid L., Rupali, Shashikant N. Dhole, Nilesh Kulkarni, and Santosh L. Shid L. "Formulation and Evaluation of Nanosuspension Delivery System for Simvastatin." International Journal of Pharmaceutical Sciences and Nanotechnology 7, no. 2 (2014): 2459–75. http://dx.doi.org/10.37285/ijpsn.2014.7.2.8.

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Poor water solubility and slow dissolution rate are issues polydispersity index. The obtained results showed that for the majority of upcoming and existing biologically active  particlesize (nm) and rate of dissolution has been improved compounds. Simvastatin is poorly water-soluble drug and when nanosuspension prepared with the higher its bioavailability is very low from its crystalline form. The concentration of PVPK-30 with the higher concentration of purpose of the present investigation was to increase the  PVP K-30 and Poloxamer-188 and lower concentration of solubility and di

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7

Shid, Rupali L., Shashikant N. Dhole, Nilesh Kulkarni, and Santosh L. Shid. "Formulation and Evaluation of Nanosuspension of Simvastatin." International Journal of Pharmaceutical Sciences and Nanotechnology 8, no. 2 (2015): 2858–73. http://dx.doi.org/10.37285/ijpsn.2015.8.2.9.

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Poor water solubility and slow dissolution rate are issues for the majority of upcoming and existing biologically active compounds. Simvastatin is poorly water-soluble drug and its bioavailability is very low from its crystalline form. The purpose of this study wasto increase the solubility and dissolution rate of simvastatin by the preparation of nanosuspension by emulsification solvent diffusion method at laboratory scale. Prepared nanosus-pension was evaluated for its particle size and in vitro dissolution study and characterized by zeta potential,differential scanning calorimetry (DSC) and

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8

Shid, Rupali L., Shashikant N. Dhole, Nilesh Kulkarni, and Santosh L. Shid. "Formulation and Evaluation of Nanosuspension Formulation for Drug Delivery of Simvastatin." International Journal of Pharmaceutical Sciences and Nanotechnology 7, no. 4 (2014): 2650–65. http://dx.doi.org/10.37285/ijpsn.2014.7.4.7.

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Poor water solubility and slow dissolution rate are issues drug content and polydispersity index. The obtained for the majority of upcoming and existing biologically results showed that particle size (nm) and rate of active compounds. Simvastatin is poorly water-soluble dissolution has been improved when nanosuspension drug and its bioavailability is very low from its crystalline prepared with the higher concentration of PVPK-30 and form. The purpose of the present investigation was to Poloxamer-188 and lower concentration of SLS. The increase the solubility and dissolution rate of simvastatin

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9

D.V. R. N., Bhikshapathi, Vishwaja M, Suthakaran R, Usha Sri B, and M. Ratan Seshagiri Rao. "Improvement of Solubility and Dissolution Rate of Simvastatin by Solid Dispersion Technique." International Journal of Pharmaceutical Sciences and Nanotechnology 12, no. 6 (2019): 4964–700. http://dx.doi.org/10.37285/ijpsn.2019.12.6.3.

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The aim of present work is to enhance the solubility and bioavailability of Simvastatin by solid dispersion technique and characterize the same. Preliminary solubility studies were conducted to check the solubility in different polymers. Based on the results 20 formulations prepared by solvent evaporation method with varying ratios of Kleptose HPB, Soluplus, Kolliwax GMS II, Kolliphor P188 and PVPK-30. All the formulations were analyzed for solubility, percentage yield, drug content and in vitro drug release. The formulation SD20 with enhanced solubility of 20.05 ± 0.02μg/mL in Kolliwax GMS II

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10

Reddy, P. Srikanth, V. Alagarsamy, and P. Subhash Chandra Bose. "Preparation, Characterization and In Vitro Evaluation of Nanosuspension for the Treatment of Schizophrenia." International Journal of Research and Review 10, no. 11 (2023): 40–47. http://dx.doi.org/10.52403/ijrr.20231106.

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The current study aims to construct a perphenazine oral nanosuspension utilizing the solvent evaporation technique with a variety of stabilizers and surfactants, including PVPK30, Pluronic F127, urea, and SLS. In order to obtain desired size and saturation solubility, several as well as process factors were tuned. Particle size, zeta potential, saturation solubility, dissolving rate, morphological study (SEM), and in-vitro dissolution study were all used to characterize the produced Nanosuspension. The improved formulation's (F12) zeta potential value was discovered to be -7mv, which was deter

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