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Rozprawy doktorskie na temat „Rational expression”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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1

Wittrup, Larsen Marianne. "Expression of a lipase in prokaryote and eukaryote host systems allowing engineering." Doctoral thesis, Stockholm : Skolan för bioteknology, Kungliga Tekniska högskolan, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-11124.

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Tanner, Delia Caroline. "Over-expression, purification and biochemical characterization of DOXP reductoisomerase and the rational design of novel anti-malarial drugs." Thesis, Rhodes University, 2004. http://hdl.handle.net/10962/d1003990.

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Malaria poses the greatest threat of all parasites to human life. Current vaccines and efficacious drugs are available however their use is limited due to toxicity, emergence of drug resistance, and cost. The discovery of an alternative pathway of isoprenoid biosynthesis, the non-mevalonate pathway, within the malarial parasite has resulted in development of novel anti-malarial drugs. 1-Deoxy-D-xylulose-5-phosphate (DOXP) reductoisomerase, the second enzyme in this pathway, is responsible for the synthesis of 2-C-methyl-D-erythritol 4-phosphate (MEP) in an intramolecular rearrangement step fol

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Bandmann, Nina. "Rational and combinatorial genetic engineering approaches for improved recombinant protein production and purification." Doctoral thesis, Stockholm : Bioteknologi, Kungliga Tekniska högskolan, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4318.

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Frouco, Gonçalo Daniel dos Santos. "Modulating chromatin structure and gene expression during African swine fever virus infection : new strategies for an efficient vaccine rational design." Doctoral thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2018. http://hdl.handle.net/10400.5/14927.

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Tese de Doutoramento em Ciências Veterinárias, na especialidade de Sanidade Animal.<br>African swine fever virus (ASFV) is a nucleo-cytoplasmic large DNA virus which infects all members of the family Suidae, causing a fatal disease of domestic swine and wild boar. Since no effective vaccine or treatment is available, ASF is considered a global threat for pig husbandry. The ASFV genome encodes among others, enzymes required for virion assembly, genome transcription and replication, including a putative histone-like protein, pA104R. In bacteria, these proteins perform topological modification of

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Gengenbach, Benjamin Bruno Verfasser], Johannes Felix [Akademischer Betreuer] [Buyel, and Lars Mathias [Akademischer Betreuer] Blank. "Rational and model-based characterization of heterologous gene expression in biological systems / Benjamin Bruno Gengenbach ; Johannes Felix Buyel, Lars M. Blank." Aachen : Universitätsbibliothek der RWTH Aachen, 2021. http://d-nb.info/1238693830/34.

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Canzoneri, Joshua Craig. "Interaction of small molecules with nucleic acid targets: from RNA secondary structure to the riobosome." Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/45769.

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Nucleic acids have proven to be viable targets for small molecule drugs. While many examples of such drugs are detailed in the literature, only a select few have found practical use in a clinical setting. These currently employed nucleic acid targeting therapies suffer from either debilitating off-target side effects or succumb to a resistance mechanism of the target. The need for new small molecules that target nucleic acids is evident. However, designing a novel drug to bind to DNA or RNA requires a detailed understanding of exactly what binding environments each nucleic acid presents. In an

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Nickoll, Philip Richard Spencer. "Converting polynomial and rational expressions to normal form." Thesis, University of Southampton, 1999. https://eprints.soton.ac.uk/50638/.

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The aim of this research is to design and implement a program that will be able to manipulate multiple algebraic expressions and transform them to a 'normalised form' . The expression to be manipulated is user defined (the user will be able to input an expression or read it from a file). This expression will be read in by a scanner and checked with a parser using a set of grammar rules which are to be defined later on. The expression will be able to contain constants (both real and imaginary), identifiers (strings or individual characters) and operators which include +, -, *, /, ( ), A (power

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8

Juric, Adrian R. "The actions/artifacts of historical agents as expressions of rational, purposive thought: R. G. Collingwood's own 'absolute presupposition'." Thesis, University of Ottawa (Canada), 1992. http://hdl.handle.net/10393/7498.

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The purpose of this thesis will be to defend R. G. Collingwood's claims about the existence, and the significance, of Absolute Presuppositions. This defense will fall into three main sections. In the first section, I will provide a detailed critical examination of the methods of metaphysical analysis prescribed by Collingwood for uncovering Absolute Presuppositions in the first place: the 'logic of question and answer'. In the second section, I will draw attention to what I take to be the main problem with the Essay on Metaphysics: the fact that this method of metaphysical analysis is never ap

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Götze, Doreen. "Weighted Unranked Tree Automata over Tree Valuation Monoids." Doctoral thesis, Universitätsbibliothek Leipzig, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-221154.

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Quantitative aspects of systems, like the maximal consumption of resources, can be modeled by weighted automata. The usual approach is to weight transitions with elements of a semiring and to define the behavior of the weighted automaton by mul- tiplying the transition weights along a run. In this thesis, we define and investigate a new class of weighted automata over unranked trees which are defined over valuation monoids. By turning to valuation monoids we use a more general cost model: the weight of a run is now determined by a global valuation function. Besides the binary cost functions im

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CARRANZA, PINEDO VICTOR RAFAEL. "THE LANDSCAPE OF AFFECTIVE MEANING." Doctoral thesis, Università degli Studi di Milano, 2022. http://hdl.handle.net/2434/933926.

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Swear words are highly colloquial expressions that have the capacity to sig- nal the speaker’s affective states, i.e., to display the speaker’s feelings with respect to a certain stimulus. For this reason, swear words are often called expressives. Which linguistic mechanisms allow swear words display affective states, and, more importantly, how can such ‘affective content’ be character- ized in a theory of meaning? Even though research on expressive meaning has produced models that integrate the affective aspects of swear words in a compositional framework, there is extensive evidence t

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SANTOS, Ana Cláudia Guedes dos. "Uma contribuição ao ensino de números irracionais e de incomensurabilidade para o ensino médio." Universidade Federal de Campina Grande, 2013. http://dspace.sti.ufcg.edu.br:8080/jspui/handle/riufcg/2161.

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Submitted by Emanuel Varela Cardoso (emanuel.varela@ufcg.edu.br) on 2018-11-09T18:09:57Z No. of bitstreams: 1 ANA CLÁUDIA GUEDES DOS SANTOS – DISSERTAÇÃO (PPGMat) 2013.pdf: 24981615 bytes, checksum: d442e8df3b32727e30684e3cbd516a9b (MD5)<br>Made available in DSpace on 2018-11-09T18:09:57Z (GMT). No. of bitstreams: 1 ANA CLÁUDIA GUEDES DOS SANTOS – DISSERTAÇÃO (PPGMat) 2013.pdf: 24981615 bytes, checksum: d442e8df3b32727e30684e3cbd516a9b (MD5) Previous issue date: 2013-08<br>Capes<br>Este trabalho tem como proposta pedagógica apresentar aos alunos o conceito de segmentos comensuráveis e de seg

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Kinoshita, Asako [Verfasser]. "Chronic effects of Fusarium-mycotoxins in rations with different concentrate proportions on gene expression of muscular and hepatic glucose transporters and insulin receptors as well as of hepatic enzymes relevant for energy metabolism in lactating dairy cows / Asako Kinoshita." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2011. http://d-nb.info/1018968431/34.

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13

Chetana, Baliga B. "Rational Elicitation of Cold Sensitive Phenotypes." Thesis, 2015. http://etd.iisc.ac.in/handle/2005/4081.

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Conditional gene expression and conditional mutants provide a means to modulate the expression of specific genes and to control the activity of their protein products in vivo, so as to be able to study their effects on the cell. Conditional mutants are functional under one set of conditions, termed ‘permissive’, while under other conditions that are ‘restrictive’, they become non-functional. The wild-type (Wt) is functional under both these conditions. Conditional mutants are especially useful for studying essential or lethal genes in an organism. In the case of temperature-sensitive (ts) and

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14

Ropková, Barbora. "Podoby malířské exprese v současném českém umění v kontextu českého a zahraničního umění." Doctoral thesis, 2017. http://www.nusl.cz/ntk/nusl-372352.

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This dissertation thesis deals with the work of three contemporary Czech artists - Josef Bolf, Jakub Špaňhel and Lubomír Typlt. The reason for choosing these three was the fact that all of the artists represent the same generation which entered the art scene in the late 1990s and their canvases can be equally described as expressive, although right at first glance there are noticeable differences in the intervention of the emotional and sense elements which participated in the creation process of the work of art, but also in its content. Contemporary expressive paintings are influenced by the

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Schmidt, Heike [Verfasser]. "Expression profiling und rationale Expressionsoptimierung am Beispiel eines prokaryontischen Wirt-, Vektor-Systems / vorgelegt von Heike Schmidt." 2008. http://d-nb.info/990507637/34.

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Pavlicová, Vladimíra. "Webová aplikace: Základní poznatky z matematiky na střední škole." Master's thesis, 2014. http://www.nusl.cz/ntk/nusl-341247.

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The presented work is intended to serve as a teaching material in particular for pupils of the first year of secondary school, focusing on the basic knowledge of mathematics. The first part of the thesis is devoted to an analysis of existing web page, which corresponds to the theme of the diploma thesis. The evaluation takes into account the expertise as well as the scope of use of interactive elements. In the next part, the created teaching material in a form of web page is presented. It deals with the subject matter of powers, roots, polynomials and rational expressions. In accordance with c

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Allemand, Carolyn Sue. "A rationale and suggestions for including sound symbolic expressive vocabulary in university-level Japanese language classroom instruction." Thesis, 2003. http://wwwlib.umi.com/cr/utexas/fullcit?p3116250.

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Götze, Doreen. "Weighted Unranked Tree Automata over Tree Valuation Monoids." Doctoral thesis, 2016. https://ul.qucosa.de/id/qucosa%3A15442.

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Quantitative aspects of systems, like the maximal consumption of resources, can be modeled by weighted automata. The usual approach is to weight transitions with elements of a semiring and to define the behavior of the weighted automaton by mul- tiplying the transition weights along a run. In this thesis, we define and investigate a new class of weighted automata over unranked trees which are defined over valuation monoids. By turning to valuation monoids we use a more general cost model: the weight of a run is now determined by a global valuation function. Besides the binary cost functions im

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19

Vahmani, Payam Jr. "Effect of Supplementation with Fish Oil or Microalgae on Milk Fatty Acid Composition and Lipogenic Gene Expression in Cows Managed in Confinement or Pasture Systems." 2013. http://hdl.handle.net/10222/36352.

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Modifying milk fat composition to enhance its content of valuable fatty acids (FA) is required to meet the needs of a society which is becoming better informed about the relationship between diet and health. Manipulating the cow’s diet is an effective, natural way to modify the amount and composition of milk fat of cows. The two main factors that affect the cow’s diet concern management system (MS; pasture vs. confinement), and supplementation of diets with lipid supplements. Marine oils specifically are fed to enhance milk with n-3 long-chain polyunsaturated FA (n-3 LC-PUFA). The effects of s

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