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Rozprawy doktorskie na temat „Regenerative activity”

Autor: Grafiati

Data publikacji: 3 czerwca 2025

Data aktualizacji: 31 lipca 2025

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Vo, Thi Diem Thi. "Development of soft tissue regenerative scaffold with antibacterial activity." Thesis, The University of Sydney, 2013. http://hdl.handle.net/2123/10202.

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With increasingly aging and sedentary populations, and with the rising incidence of diabetes and the associated diabetic ulcers, chronic wounds have been reported to be approaching pandemic proportions. Accumulation of wound bacteria forms a biofilm that can inhibit wound healing and the action of antibiotics. Conventional skin grafts can readily harbor bacterial and fungal cells while excluding penetration of larger immune cells and essential neo-vascularization. Soft tissue regenerative scaffolds with highly interconnected porosity have been developed for wound healing. In this research, sca

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Salick, Daphne Ann. "Cytocompatibility, antibacterial activity and biodegradability of self-assembling beta-hairpin peptide-based hydrogels for tissue regenerative applications." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 209 p, 2009. http://proquest.umi.com/pqdweb?did=1674096141&sid=4&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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Trovato, Paolo. "In vivo binary genetic mosaics via Beatrix: a reliable sensor of cell genome obtained by a regenerative amplifier of Cre activity." Doctoral thesis, Scuola Normale Superiore, 2019. http://hdl.handle.net/11384/85927.

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Genetic mosaicism is a condition in which an organ includes cells with different genotypes. The difference can be due to the mutation of a single gene, as it is often the case with several monogenic diseases of the central nervous system, where the mosaicism is caused either by somatic mutations affecting only a subset of cells, or by the random inactivation of the X chromosome, in the case of X-linked pathologies. The understanding of the mechanistic basis of these diseases would benefit by the creation of models where the genotype of each cell is univocally identified by the expression of a

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Taheri, Moosavi Seyedehsomayeh. "An activity-based approach to neighbourhood regeneration." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/an-activitybased-approach-to-neighbourhood-regeneration(d9f5fd0d-1b84-4969-9f1a-6b422e987134).html.

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Neighbourhood design is a part of sustainable development, and attempts to create better places for people by reflecting residents' values, as well as coordinating powers, resources, and actions between stakeholders. This research aims to investigate neighbourhood regeneration plans using an activity-based approach. It explores how daily social activities can be modelled using the case study of Brunswick, to develop the analytical and decision-support roles of modelling in the urban design process. The literature about the role of design in urban development argues that the designers' attempts

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Vujic, Nikola. "Power Regeneration in Actively Controlled Structures." Thesis, Virginia Tech, 2002. http://hdl.handle.net/10919/33425.

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The power requirements imposed on an active vibration isolation system are quite important to the overall system design. In order to improve the efficiency of an active isolation system we analyze different feedback control strategies which will provide electrical energy regeneration. The active isolation system is modeled in a state-space form for two different types of actuators: a piezoelectric stack actuator and a linear electromagnetic (EM) actuator. During regenerative operation, the power is flowing from the mechanical disturbance through the electromechanical actuator and its switching

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Goganau, Ioana [Verfasser], and Armin [Akademischer Betreuer] Blesch. "Electrical stimulation and activity for axonal regeneration / Ioana Goganau ; Betreuer: Armin Blesch." Heidelberg : Universitätsbibliothek Heidelberg, 2016. http://d-nb.info/1180736885/34.

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Cloutier, Jennifer K. (Jennifer Kruse). "Activin signaling controls a wound-induced program essential for regenerative patterning." Thesis, Massachusetts Institute of Technology, 2020. https://hdl.handle.net/1721.1/127124.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, May, 2020<br>Cataloged from the official PDF of thesis.<br>Includes bibliographical references.<br>A central problem in animal regeneration is how animals determine what body part to regenerate. Planarians are flatworms that can regenerate any missing body part, and are studied to identify mechanisms underlying regeneration. At transverse amputation planes, a poorly understood mechanism specifies regeneration of either a head or a tail. This head-versus-tail regeneration decision-making process is referred to as rege

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Nöske, Katharina [Verfasser], and Petra [Akademischer Betreuer] Boukamp. "Mitotic activity of keratinocytes in regeneration and tissue homestasis / Katharina Nöske ; Betreuer: Petra Boukamp." Heidelberg : Universitätsbibliothek Heidelberg, 2015. http://d-nb.info/1180500814/34.

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Ruppell, Kendra Takle. "Neural Bursting Activity Mediates Subtype-Specific Neural Regeneration by an L-type Calcium Channel." eScholarship@UMMS, 2019. https://escholarship.umassmed.edu/gsbs_diss/1032.

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Axons are injured after stroke, spinal cord injury, or neurodegenerative disease such as ALS. Most axons do not regenerate. A recent report suggests that not all neurons are poor regenerators, but rather a small subset can regenerate robustly. What intrinsic property of these regenerating neurons allows them to regenerate, but not their neighbors, remains a mystery. This subtype-specific regeneration has also been observed in Drosophila larvae sensory neurons. We exploited this powerful genetic system to unravel the intrinsic mechanism of subtype-specific neuron regeneration. We found that neu

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Wright, Bryan D. "Urban Regeneration and Immigrant Representation in Non-Gateway Cities." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1414750325.

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Erland, Lauren Alexandra Elizabeth. "Enhancement of specialized metabolism, regeneration efficiency and biological activity in lavandin (Lavandula x intermedia cv 'Grosso')." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/52707.

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This study aimed to improve essential oil composition by modifying terpene production in Lavandula x intermedia cv Grosso via mutagenesis to more closely resemble the oil of the commercially valuable essential oil from L. angustifolia or the medicinally active essential oil from L. latifolia. Additionally this study aimed to identify genes that control essential oil production in lavenders, and to determine the effect of essential oil composition on biological activity, specifically insecticidal and insect repellent properties. This study resulted in an improved method for the efficient regene

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Taylor, Martin Russell. "An evaluation of bird presence and breeding activity in regenerating coastal dune forests, Maputaland, South Africa." Diss., Pretoria : [s.n.], 2007. http://upetd.up.ac.za/thesis/available/etd-04172008-093938.

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Jeon, Ju Hyeong. "CONTROLLED RELEASE OF OSTEOTROPIC MOLECULES STIMULATES IN VITRO CELLULAR ACTIVITY AND IN VIVO LOCAL BONE REGENERATION." UKnowledge, 2007. http://uknowledge.uky.edu/gradschool_diss/574.

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Bone defects treatment and reconstructive surgery continues to increase at a significant rate. Current bone defect treatments are autotransplantation, allograft, and xenografts create many problems such as, inflammation, infection and chronic pain. Moreover, allografts and xenografts arouse immune rejection. These problems have led to development of controlled release system for use as alternatives to autografts, allografts and xenografts in bone repair. There have been many approaches for sustained drug delivery in local bone regeneration using biodegradable polymers and osteotropic biomolecu

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Wooller, Leslie Ann. "What are the economic and travel implications of pedestrianising a roadway in Takapuna’s shopping precinct." AUT University, 2010. http://hdl.handle.net/10292/999.

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Transforming car-oriented streets into functional public spaces and pedestrianised environments have typically been undervalued in conventional transportation, planning, and health literature. Yet urban regeneration initiatives have the potential to create environments that support active transport (e.g., walking and cycling), social interaction, and economic development. There is very little evidence-based research, however, around pedestrianisation. Few international studies have examined the association between pedestrianisation with health, social and economic outcomes from a stakeholder p

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Walsh, Shane Benedict. "Characterising demixed polymer surfaces to stimulate mesenchymal stromal cell activity and influence tissue development during osteochrondral regeneration." Thesis, University of Newcastle upon Tyne, 2015. http://hdl.handle.net/10443/3082.

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Osteoarthritis (OA) is defined clinically as the world’s leading cause of joint disease. Better understanding of the disease aetiology, contributing factors and improved imaging technologies has changed how we can treat this disease. Early intervention and long-term implant integration has inspired a new generation of biomaterials, able to influence local biological events in situ. The response of cells to their physical environment is known to regulate their proliferation, phenotype, gene expression and differentiation. To rebuild tissue with the appropriate structural and cellular organisati

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Berger, N. "Neighbourhood and home environments and adolescent physical activity behaviours : longitudinal analyses of the Olympic Regeneration in East London (ORiEL) study." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2018. http://researchonline.lshtm.ac.uk/4649763/.

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Context: Regular physical activity has been shown to prevent major non-communicable diseases and improve physical and mental health. However, a quarter of adults and the majority of adolescents do not achieve the recommended level of physical activity in England. In recent years, the home and neighbourhood environments as determinants of physical activity have received attention because of their proximal influence on everyday behaviours, especially in young people. The current literature on adolescents is however limited. This thesis aims to investigate whether features of the home and neighbo

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Pagano, Allan. "Déconditionnement et régénération du muscle strié squelettique : rôle du niveau d’activité contractile sur le développement d’infiltrations graisseuses." Thesis, Montpellier, 2016. http://www.theses.fr/2016MONT4004/document.

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Le muscle strié squelettique est un tissu fascinant qui permet d’assurer les fonctions essentielles à notre existence : se mouvoir, maintenir sa posture, se nourrir, communiquer ou tout simplement respirer. De nombreuses situations, engendrant principalement une hypoactivité, peuvent provoquer un déconditionnement musculaire caractérisé par une perte de masse et de force ainsi qu’un développement d’infiltrations graisseuses (IMAT), altérant ainsi la fonction musculaire. Le développement d’IMAT est également observé lorsque les processus de régénération musculaire sont altérés. Les fibro-adipog

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Hoban, Martin. "Humanising development and regeneration : a dialogical enquiry with grassroots activists and community workers in Rhondda Cynon Taff." Thesis, Brunel University, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428060.

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Schofield, Sandra Jaqueline. "Social exclusion : an ethnography of community leadership and grass roots activism in the quest for urban regeneration." Thesis, Manchester Metropolitan University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.263688.

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Angonin, Diane. "Lineage-specific manipulation of subventricular zone germinal activity for neonatal cortical repair." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSE1175/document.

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L'hypoxie périnatale entraîne une dégénérescence et un délai de maturation des oligodendrocytes et des neurones corticaux du cortex cerebral. Mon projet de thèse a d'abord consisté à étudier la contribution des cellules souche neurales de la zone sous-ventriculaire dorsale (dSVZ) à la tentative de régénération spontanée observée après la lésion. Dans un second temps, j'ai étudié la capacité de ces cellules souches à être manipulée en utilisant une approche pharmacologique.Mes résultats mettent en évidence une réponse spontanée et dynamique de la dSVZ qui produit des neurones et des oligodendro

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RAKOTOMANOMANA, RAKOTOBE SUZE. "Peche et aquaculture dans les regions de l'arc atlantique (ou comment des activites de type primaire peuvent-elles contribuer a la regeneration de regions marginales ?)." Nantes, 1998. http://www.theses.fr/1998NANT3024.

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Conscient de son desequilibre actuel face aux autres regions europeennes, l'arc atlantique veut affirmer son existence et sa volonte de developpement dans tous les domaines. Par ses multiples facettes et son imbrication dans le paysage economique europeen, la peche, activite commune a tous les pays de l'arc, est un sujet d'etudes interessant au travers duquel l'arc atlantique se definit comme une veritable entite economique, aujourd'hui plus que jamais au coeur de l'actualite. L'analyse qualitative et quantitative des structures et des rouages, des impacts et des conflits de cette activite eco

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Knaack, Sven. "Entwicklung und Charakterisierung von Scaffolds auf Basis von mineralisiertem Kollagen zur gezielten Wirkstofffreisetzung für die Knochengewebe-Regeneration." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-188547.

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Beim Tissue Engineering ist die Vaskularisierung von größeren Zell-Matrix-Konstrukten nach Implantation bis heute ein großes Problem. Durch das initiale Fehlen eines mikrovaskulären Netzwerkes kommt es zu einem raschen Zellsterben im Scaffold. Aufgrund dessen war das Ziel dieser Arbeit, im Sinne des in situ-Tissue Engineering ein Scaffold auf Basis von mineralisiertem Kollagen zu entwickeln, welches mit dem angiogenen Wachstumsfaktor VEGF funktionalisiert wird, um den Prozess der Vaskularisierung – die Einsprossung von Blutgefäßen – zu fördern und gleichzeitig durch Chemoattraktion in vivo Z

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Asante, Lewis Abedi. "The Politics and Activism of Urban Governance in Ghana: Analyzing the Processes of Market Redevelopment in Kumasi and Cape Coast." Doctoral thesis, Humboldt-Universität zu Berlin, 2020. http://dx.doi.org/10.18452/21129.

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Stadterneuerung in Ghana ist seit Jahren auch durch den Widerstand von Bürgerinnen und Bürgern geprägt. Auf der Grundlage einer qualitativen Analyse und Fallstudie zur Sanierung von Marktinfrastrukturen in Kumasi und Cape Coast zeigt diese kumulative Dissertation, dass es zum besseren Verständnis der Ursachen von zivilem Widerstand insbesondere Aufmerksamkeit für die Qualität der Governance-Prozesse selbst bedarf. Marktsanierungsprojekte in Ghana sind durch fünf Prozessphasen geprägt: Scoping, Planung, Finanzierung, Standortverlagerung und -zuweisung. In allen Phasen lassen sich jeweils ander

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Cabrera-Codony, Alba. "Siloxane removal in the energy recovery of biogas: sequential adsorption/oxidation processes." Doctoral thesis, Universitat de Girona, 2016. http://hdl.handle.net/10803/399731.

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The thesis deals with removal of organosilicon compounds in the energy recovery of biogas. Alternative adsorbents for the siloxane removal were studied, and the physical and chemical mechanisms involved in the siloxane adsorption were discovered, which improved the yield of the adsorption and regeneration technologies using both activated carbons and zeolites. Moreover, several technologies based on advanced oxidation processes have been applied in order to regenerate and reuse the exhausted adsorbents. The thesis studies the siloxane removal at lab-scale close to real scenario conditions, in

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Geraldes, Ana Maria. "Efeitos da ocupação do solo, do uso da água e da idade das albufeiras nos parâmetros ambientais e na estrutura das comunidades zooplanctónicas." Doctoral thesis, Universidade de Lisboa, Faculdade de Ciências, 2004. http://hdl.handle.net/10198/770.

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O presente trabalho decorreu em três albufeiras de idades distintas e sujeitas a diferentes tipos de perturbações de origem antropogénica. Estes sistemas aquáticos localizam-se na parte portuguesa da Bacia Hidrográfica do Rio Douro, na região de Trás-os-Montes. A albufeira da Serra Serrada foi criada em 1995 com o objectivo de abastecer de água a cidade de Bragança, actualmente com 34.750 habitantes. Como consequência do intenso consumo de água ocorrem flutuações de grande amplitude no seu nível. Por outro lado, na bacia de drenagem desta albufeira a pastorícia é particularmente intensa durant

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Goulas, Philippe. "Etude de déshydrogénases a NAD(P) : Utilisation en synthèse organique." Université Louis Pasteur (Strasbourg) (1971-2008), 1986. http://www.theses.fr/1986STR13005.

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Etude des problèmes liés à l'utilisation des déshydrogénases a NAD(P) en synthèse organique. Etude, à l'aide d'analogues structuraux du NAD(P), de la 6-phosphogluconate déshydrogénase de Candida Utilis et de l'oestradiol déshydrogénase de placenta humain. Synthese d'un complexe covalent NAD-alcool déshydrogénase du foie de cheval, catalytiquement actif. Purification de la carnitine déshydrogénase de Pseudomonas Putida et la mise en oeuvre pour la synthèse stéréospécifique de la l-carnitine. Mise au point d'une électrode à enzyme spécifique de la l-carnitine

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Alves, Carolina dos Santos. "Regenerative neurogenesis in Drosophila melanogaster: The influence of age and activity in the adult brain." Master's thesis, 2017. http://hdl.handle.net/10400.12/6406.

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Dissertação de Mestrado apresentada no ISPA - Instituto Universitário para obtenção de grau de Mestre na especialidade em Neurociências Cognitivas e Comportamentais.<br>Sendo o Encéfalo um dos órgãos mais importantes do organismo, a descoberta de que o processo de neurogénese continuava presente durante a fase adulta do animal foi uma das grandes revelações científcas da última metade do século XX. Assim, uma das vantagens na investigação deste processo: Neurogénese Adulta, é a sua aplicação em diversos organismos, que posteriormente possibilitará uma compreensão mais completa e aprofundada do

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Sacramento, Joana Filipa Canais da Costa. "Modulation of carotid body activity as a therapeutic intervention in metabolic diseases." Doctoral thesis, 2018. http://hdl.handle.net/10362/64174.

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A diabetes tipo 2 é uma das doenças crónicas mais comuns no mundo, cuja prevalência continua a aumentar. Em 2045 estima-se que esta doença afete cerca de 629 milhões de pessoas no mundo. A diabetes tipo 2 é caracterizada pela resistência periférica à insulina, o anormal metabolismo hepático de glucose e a falha progressiva das células beta do pâncreas. Existem vários fármacos disponíveis para o tratamento da diabetes tipo 2 contudo, com o tempo, o controlo da glucose deteriora-se progressivamente e, mesmo com ajustes na medicação, uma proporção considerável de indivíduos continua pouco contro

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Renn, Ting-Yi, and 任婷怡. "Cell model assessment of the anti-inflammatory activity of plasma/platelet fractions used in regenerative medicine." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/6bq7ye.

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碩士<br>臺北醫學大學<br>生醫材料暨組織工程研究所<br>102<br>Platelet materials, known as platelet-rich-plasma (PRP), platelet gel (PG) or platelet lysate (PL), are increasingly used in regenerative medicine, e.g. in oral and maxillo-facial surgeries, cartilage regeneration, and soft tissue healing. In addition to promoting tissue repair and bone regeneration, these platelet materials have been claimed to limit post-surgical inflammation and reduce pain in patients, possibly thanks to their content in anti-inflammatory growth factors, such as transforming growth factor (TGF)-β1 and hepatocyte growth factor (HGF). H

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Pauly, Katherine L. "The effects of electromagnetic wave stimulation (EMS) on osteoblast differentiation and activity." Thesis, 2020. http://hdl.handle.net/1805/23185.

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Indiana University School of Dentistry<br>Introduction: The goal of nonsurgical root canal therapy is to reduce the bacterial load within an infected root canal system, and the subsequent objective is to prevent or treat apical periodontitis. Clinical studies have shown more expedient healing of apical periodontitis treated with electromagnetic wave stimulation (EMS) as compared to apical periodontitis not treated with EMS. Stimulation of osteoblasts and growth factors has been shown when EMS was applied to rat calvaria, resulting in increased bone healing. Objective: The purpose of this vitr

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McIntyre, Patrick. "The Effects of a Pyk2 Kinase Inhibitor on the Proliferation and Differentiation of Human Dental Pulp Stem Cells." Thesis, 2021. http://dx.doi.org/10.7912/C2/24.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Introduction: Regenerative endodontic procedures are an effective treatment option for immature teeth with infected necrotic pulps to allow for healing and potential continued root development, yet challenges to ideal treatment outcomes remain. Consistent development of root length and width of dentin remains a challenge, as does development of the pulp-dentin complex. Previous in vitro studies have assessed the role of different growth factors and bioactive molecules in combination with scaffolds to potentially facilitate continued

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Fischer, Benjamin I. "The impact of hydroxyapatite on alkaline phosphatase activity and mineral deposition of dental pulp stem cells using a double antibiotic paste loaded methylcellulose carrier." Thesis, 2020. http://hdl.handle.net/1805/23133.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Introduction: Regenerative endodontic procedures (REPs) are a type of endodontic treatment aimed at replacing damaged tooth structures, including dentin and root structures, as well as cells of the pulp-dentin complex. Double antibiotic paste (DAP) has been shown to be efficacious in achieving disinfection of the root canal system while minimizing cytotoxicity to dental pulp stem cells (DPSCs). Hydroxyapatite (HA) is an extracellular, mineralized component of bone that has shown much promise as a scaffold in the field of regenerative

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Wu, Buor-Chang, and 吳伯璋. "The antibacterial activity of radiopaque dicalcium silicate cement for bone regeneration." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/07277242252553547495.

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博士<br>中山醫學大學<br>牙醫學系博士班<br>102<br>To comparatively examine the cell attachment, cytotoxicity, and antibacterial activity of radiopaque dicalcium silicate cement (RDSC) and ProRoot white-coloured mineral trioxide aggregate (WMTA). In addition, this study compared the regenerative potential of RDSC and WMTAusing a rabbit femur model. AlamarBlue was used for real-time and repeated monitoring of MG63 cell attachment on freshly mixed and set cements. The pH changes in the growth medium at different time-points were also measured. Cytotoxicity evaluation was performed according to ISO 10993–5 specif

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Cheng, Yao-Ling, and 鄭耀齡. "Delay-Time-Tunable Actively and Regeneratively Mode-Locked Erbium-Doped Fiber Lasers." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/01522696831327114308.

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碩士<br>大同大學<br>光電工程研究所<br>89<br>In this thesis we demonstrate for the first time a delay-time tunable, actively and regenerately mode-locked erbium-doped fiber ring laser (ML-EDFL). Such a new class of ML-EDFL systems are integrated by using a typical ML-EDFL set and a frequency-translated delay-locked loop (DLL). The theoretical and experimental analysis of a new type of broad-band microwave phase shifter implemented by using frequency-translated DLL and frequency prescalers are demonstrated. By adding a continuously tunable offset voltage prior to the loop filter (LF) in a phase-locked loo

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Gilbert, Richard W. D. "Characterization of TGFb signaling during epimorphic tissue regeneration: an example using the leopard gecko (Eublepharis macularius) tail regeneration model." Thesis, 2013. http://hdl.handle.net/10214/6609.

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The transforming growth factor beta (TGFβ)/activin signaling pathway has a number of documented roles during wound healing and is becoming increasingly appreciated as a vital component of multi-tissue regeneration. The leopard gecko (Eublepharis macularius) is able to spontaneously, and repeatedly, regenerate its tail following tail loss. We thus examined the expression and localization of several key components of the TGFβ/activin signaling pathway during tail regeneration of the leopard gecko. We observed a marked increase in phosphorylated-Smad2 expression among regenerating tissues corresp

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Enes, Joana [Verfasser]. "Electrical activity suppresses intrinsic growth competence in adult primary sensory neurons : implications for spinal cord regeneration / vorgelegt von Joana Enes." 2009. http://d-nb.info/994590504/34.

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Hou, Fen-Han, та 侯棻涵. "Characterization of Activin/TGF-β Signaling in the Wound Healing and Early Anterior Regeneration of Aeolosoma viride". Thesis, 2014. http://ndltd.ncl.edu.tw/handle/zcyhv4.

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碩士<br>國立臺灣大學<br>生命科學系<br>102<br>Activin, a TGFβ superfamily protein, is known to regulate cell proliferation, inflammation, apoptosis, regeneration, and wound healing. Previous researches demonstrated that activin is necessary for wound healing in mice and fin regeneration in zebrafish. Recently, follistatin has been linked to regeneration in planarians. In this research, we investigated the roles of activin in the wound healing of a small fresh water annelid, Aeolosoma viride. A.viride can fully regenerate the head within 5 days after amputation. The results showed activin expression is upreg

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Hsu, Wei-Hsin, and 徐維信. "Early activation of liver regeneration by splenectomy in hepatectomised rat via decreased expression of Activin-a of liver tissue." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/26724178277267923386.

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碩士<br>國立成功大學<br>分子醫學研究所<br>93<br>Splenectomy enhanced liver regeneration was noticed for a long time. However, which factor was involved in this phenomenon is inconclusive. In this study, we used partial hepatectomised rat as a animal model to observe the expression of factors in liver regeneration. The ratio of regenerating liver and rat body weight at the time point 1 and 2 days in experimental group (partial hepatectmoy and splenectomy) is greater than that of control group (partial hepatectmy). Expression of RT-PCR of IL-6 in liver tissue of experimental group is lower than that of control

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ŠKÁCHOVÁ, Eva. "Tréninkový proces jako součást harmonického rozvoje zdravého sportovce (oblast atletických sprintů)\\." Master's thesis, 2008. http://www.nusl.cz/ntk/nusl-45523.

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This thesis engages general influence by sports in the harmonious development healthy sportsmen in area of athletics sprint. At first it was necessary to find the newest informations about training and health. Afterwards these informations assort and process to form of literary study. The second part of this thesis uses these informations and target of this part was to create an project of training by using of method theoretical synthesis.

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Wilson, Lara Ruth. "Urban activator : a contextually generated mixed-use building." Diss., 2008. http://hdl.handle.net/2263/26845.

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Set in the historic centre of Pretoria CBD, this study draws extensively on its context to formulate an appropriate response to bringing about urban regeneration in this section of the city. The study was initiated with the selection of a small site set in the percieved northern portion of the inner city. By challenging both the alleged threshold between the 'north' and the 'inner city' and the city council's proposal for the surrounding sites, the proposed building attempts to create meaningful space while enriching the visitor's experience of his immediate surroundings.<br>Dissertation (MArc

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Knaack, Sven. "Entwicklung und Charakterisierung von Scaffolds auf Basis von mineralisiertem Kollagen zur gezielten Wirkstofffreisetzung für die Knochengewebe-Regeneration." Doctoral thesis, 2015. https://tud.qucosa.de/id/qucosa%3A29043.

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Beim Tissue Engineering ist die Vaskularisierung von größeren Zell-Matrix-Konstrukten nach Implantation bis heute ein großes Problem. Durch das initiale Fehlen eines mikrovaskulären Netzwerkes kommt es zu einem raschen Zellsterben im Scaffold. Aufgrund dessen war das Ziel dieser Arbeit, im Sinne des in situ-Tissue Engineering ein Scaffold auf Basis von mineralisiertem Kollagen zu entwickeln, welches mit dem angiogenen Wachstumsfaktor VEGF funktionalisiert wird, um den Prozess der Vaskularisierung – die Einsprossung von Blutgefäßen – zu fördern und gleichzeitig durch Chemoattraktion in vivo Z

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Palacio, Lina. "Study of the role of the p16INK4a gene in tumor progression and tissue regeneration/function following exposure to ionizing radiation." Thesis, 2017. http://hdl.handle.net/1866/24855.

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La sénescence est un important mécanisme cellulaire qui prévient la tumorigenèse et se caractérise par un arrêt permanent du cycle cellulaire orchestré principalement par les inhibiteurs des cycline-kinases dépendantes (i.e p16INK4a). La sénescence est une caractéristique importante du vieillissement, mais un déséquilibre dans son induction peut être délétère pour la régénération tissulaire et paradoxalement pour la progression tumorale. L'irradiation (IR) est couramment utilisée comme approche thérapeutique dans le cancer. Chez les enfants survivants du cancer, l’exposition à l’irradiation et

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Zlotkowski, Katherine Hannah. "Chemical biology studies of neuroregenerative small molecules using Caenorhabditis elegans." Thesis, 2015. http://hdl.handle.net/2152/30511.

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The debilitating effects of spinal cord injury can be attributed to a lack of regeneration in the central nervous system. Identification of growth-promoting pathways, particularly ones that can be controlled by small molecules, could provide significant advancements in regenerative science and lead to potential treatments for spinal cord injury. The biological investigations of neuroregenerative small molecules, specifically the natural products clovanemagnolol and vinaxanthone, have been expanded to a whole organism context using the nematode Caenorhabditis elegans (C. elegans) as a tool fo

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