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1

Campbell, Eilidh. Throughcare programmes and their effect upon overdose and relapse rates of male prisoners upon release.. University of Paisley, 1997.

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2

Kaplan, Tamara B., and Marcelo Matiello. Multiple Sclerosis. Edited by Angela O’Neal. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190609917.003.0026.

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Multiple sclerosis (MS) often affects women of childbearing age. There are many issues to consider when counseling women about their disease and treatment during this time. The Pregnancy in Multiple Sclerosis (PRIMS) study, published in 1998, is the best large-scale prospective study published to date. Based on this trial, and those that followed, it is recognized that the rate of relapse in MS decreases during pregnancy, especially during the third trimester, but there is a significant increase in relapse rate in the first three months postpartum. If relapses do occur during pregnancy, women
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3

Muralidharan, Anjana, David J. Miklowitz, and W. Edward Craighead. Psychosocial Treatments for Bipolar Disorder. Oxford University Press, 2015. http://dx.doi.org/10.1093/med:psych/9780199342211.003.0010.

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Pharmacological interventions remain the primary treatment for bipolar disorder. However, adjunctive psychosocial interventions have the potential to increase adherence to medication regimens, decrease hospitalizations and relapses, decrease severity of symptoms, improve quality of life, and enhance mechanisms for coping with stress. Group psychoeducation, designed to provide information to bipolar patients about the disorder and its treatment, leads to lower rates of recurrence and greater adherence to medication among remitted bipolar patients at both short- and long-term follow-up. Cognitiv
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4

Hansen, Kevin T. The affect of psychotherapy and pharmacological treatment on sex offender relapse rates. 2004.

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5

Williams, Roland. Relapse Prevention Workbook for African Americans: Hope and Healing for the Black Substance Abuser. Inst Econ & Financial Res, 1999.

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6

Lin, Eric, and Pochu Ho. Sequenced Treatment Alternatives to Relieve Depression. Edited by Ish P. Bhalla, Rajesh R. Tampi, Vinod H. Srihari, and Michael E. Hochman. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190625085.003.0027.

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This chapter provides a summary of the landmark Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial on major depressive disorder. The STAR*D trial was designed to address some basic questions about depression treatment. What are the outcomes and the remission rates for depression? What are the long-term outcomes, especially the relapse rates, for patients receiving sequential depression therapies? Starting with these questions, this chapter describes the basics of the STAR*D trial, including funding, study location, study population, number of study participants, study design
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Venkatesan, Arun. Central Nervous System Whipple Disease. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0169.

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Whipple disease (WD) is a multisystemic infection caused by the bacillus Tropheryma whipplei. Although the organism is ubiquitous in the environment, WD is rare. In affected individuals, the organism resides intracellularly within macrophages and can manipulate host immune responses to avoid clearance. Central nervous system (CNS) involvement can occur as a manifestation of classic WD, in the setting of a relapse of previously treated WD, or rarely as isolated nervous system infection. Diagnosis of CNS WD rests on polymerase chain reaction (PCR) and demonstration of periodic acid-Schiff (PAS)
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8

Ajithkumar, Thankamma, Ann Barrett, Helen Hatcher, and Natalie Cook. Head & neck cancer. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235636.003.0004.

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The head and neck region encompasses anatomical sites below the brain and above the clavicles, excluding skin and thyroid. The sites most commonly involved with cancer are the oral cavity, larynx, and pharynx. Overall 5-year survival rates for head and neck cancer have improved only slightly over the past two decades remaining at just over 50%. This figure in part reflects the population who present with this disease in terms of age and comorbidity (typically about 15% intercurrent death rates at 5 years), as well as the tendency to develop second primaries and metastases. The poor long-term s
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9

Harper, Lorraine, and David Jayne. The patient with vasculitis. Edited by Giuseppe Remuzzi. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0160.

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The goals of treatment in renal vasculitis are to stop vasculitic activity and recover renal function. Subsequent strategies are required to prevent vasculitis returning and to address longer-term co-morbidities caused by tissue damage, drug toxicity, and increased cardiovascular and malignancy risk.Cyclophosphamide and high-dose glucocorticoids remain the standard induction therapy with alternative immunosuppressives, such as azathioprine, to prevent relapse. Plasma exchange improves renal recovery in severe presentations. Refractory disease resulting from a failure of induction or remission
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10

Abbas, Atheir I., and Jeffrey A. Lieberman. Pharmacological Treatments for Schizophrenia. Oxford University Press, 2015. http://dx.doi.org/10.1093/med:psych/9780199342211.003.0006.

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Schizophrenia, a chronic mental disorder, has a lifetime prevalence rate of approximately 1%. The first antipsychotic drug, chlorpromazine, was introduced in 1954, followed by several similar drugs. With the introduction of clozapine, risperidone, olanzapine, quetiapine, ziprasidone, aripiprazole, and more recently paliperidone, iloperidone, asenapine, and lurasidone, antipsychotic drugs are often classified as first generation or typical (chlorpromazine-like) versus second generation or atypical (clozapine-like), although the distinction between the two classes, particularly with respect to e
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11

Karan, Lori D. Pain and Addiction in Patients Who Smoke Cigarettes (DRAFT). Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190265366.003.0029.

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Through a discussion of the effects of cigarette smoking on both pain perception and other substance use, this chapter outlines the presentation of the benefits to the patient and reviews smoking cessation strategies. It begins with an epidemiological review of the higher prevalence of smoking among those with chronic pain syndromes, such as fibromyalgia, headache, and low back pain. The many adverse consequences of cigarette smoking for general health are identified, from enhanced osteoporosis to prolonged wound repair. Most strikingly, smoking is demonstrated to both exacerbate the experienc
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12

Wenzel, Amy, and Deborah Kim. Psychopharmacology in Pregnancy and the Postpartum Period. Edited by Amy Wenzel. Oxford University Press, 2015. http://dx.doi.org/10.1093/oxfordhb/9780199778072.013.21.

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A substantial minority of pregnant and lactating women meet criteria for one or more mental health disorders and, in many of these cases, treatment with psychotropic medication is indicated. Data from empirical studies on psychopharmacology using antidepressant medications for perinatal women suggest that the risk-benefit ratio is favorable, although their usage during pregnancy is associated with a slight increase in risk of spontaneous abortion, cardiac malformations (specifically with paroxetine), preterm birth, and poor neonatal adaptation syndrome. However, these risks should be contraste
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13

Foa, Edna B., Kelly R. Chrestman, and Eva Gilboa-Schechtman. Prolonged Exposure Therapy for Adolescents with PTSD Therapist Guide. Oxford University Press, 2008. http://dx.doi.org/10.1093/med:psych/9780195331745.001.0001.

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Traumatic events, including sexual abuse, experiencing or witnessing violence, and natural disasters, are common among adolescents, and this online therapist guide presents a proven treatment for PTSD that has been adapted for the adolescent population. It applies the principles of Prolonged Exposure (PE) to help adolescents emotionally process their traumatic experiences and follows a four-phase treatment where the patients complete each module at their own rate of progress. It includes modules on motivational interviewing, case management, the rationale for treatment, information-gathering a
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14

Jayne, David. Treatment of ANCA-associated vasculitis. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0132.

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The goals of treatment in anti-neutrophil cytoplasm antibody (ANCA) vasculitis are to stop vasculitic activity, to prevent vasculitis returning, and to address longer-term comorbidities caused by tissue damage, drug toxicity, and increased cardiovascular and malignancy risk. Cyclophosphamide and high-dose glucocorticoids remain the standard induction therapy with alternative immunosuppressives, such as methotrexate or azathioprine, to prevent relapse. Refractory disease resulting from a failure of induction or remission maintenance therapy requires alternative agents and rituximab has been par
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15

Al-Darraji, Haider A., and Frederick L. Altice. The Perfect Storm. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199374847.003.0008.

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Globally, tuberculosis (TB) is a major cause of morbidity and mortality among people who use drugs (PWUD), particularly those co-infected with HIV. This chapter describes how TB is prevalent in several prison systems by virtue of the concentration of PWUD and people living with HIV. TB is further amplified within this system through overcrowding, poor ventilation, and delayed access to quality prevention and treatment services. In many countries, individuals cycling through prisons are inadequately screened and treated for TB, and affected individuals may have frequent treatment interruptions.
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16

Meyer, Jaimie P., and Frederick L. Altice. Transition to the community. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199360574.003.0047.

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Re-incarceration of former prisoners is commonly associated with relapse to drug and alcohol use because of ineffective treatment of substance use disorders (SUDs) after release. High entry rates of people who use drugs (PWUDs) into prisons or jails results in the criminal justice system (CJS) bearing a disproportionate burden of the epidemic of people with SUDs. In contrast to 8% of U.S. adults in the general population, up to 65% of prisoners meet DSM-IV criteria for having a SUD and, depending on geographical location, 70% of HIV-infected prisoners meet criteria for opioid dependence. Thoug
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17

Kinner, Stuart A., and Josiah D. Rich. Drug Use in Prisoners. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199374847.003.0019.

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Drug use and crime seem inextricably linked. Law enforcement responses to drug use tend to funnel people who use drugs into the criminal justice system rather than treatment, and those drug users who are imprisoned often have multiple, co-occurring mental health problems and/or suffer from infectious diseases including HIV, hepatitis C, and tuberculosis. Prisons provide a rare but regrettable opportunity to identify and respond to these needs, but correctional policies with respect to drug use and related harms often diverge from the evidence. Where such responses are evidence-based, they are
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18

Weisman de Mamani, Amy, Merranda McLaughlin, Olivia Altamirano, Daisy Lopez, and Salman Shaheen Ahmad. Culturally Informed Therapy for Schizophrenia. Oxford University Press, 2020. http://dx.doi.org/10.1093/med-psych/9780197500644.001.0001.

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This book is primarily designed for clinicians and researchers interested in learning how to conduct an empirically supported culturally informed therapy for schizophrenia (CIT-S) that integrates core components of evidenced-based family therapy. It is estimated that approximately 1% of adults in the United States will be diagnosed with schizophrenia or a related schizophrenia spectrum disorder. Without treatment, prognosis is generally poor. Fortunately, traditional family therapies have shown increasing promise in reducing relapse rates and improving mental health for this population. As mor
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