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Rozprawy doktorskie na temat „RNA viruses Genetics”

Autor: Grafiati

Data publikacji: 4 czerwca 2021

Data aktualizacji: 31 stycznia 2023

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1

Afsharifar, Alireza. "Characterisation of minor RNAs associated with plants infected with cucumber mosaic virus." Title page, table of contents and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09pha2584.pdf.

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Bibliography: leaves 127-138. This thesis studies the minor double stranded RNAs (dsRNA) and single stranded RNAs (ssRNA) which are consistently associated with plants infected with Q strain of cucumber mosaic virus (Q-CMV). The investigations are focused on the structural elucidation of new RNAs which have been observed in single stranded and double stranded RNA profiles of Q strain of CMV.

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2

Upton, John H. "The role of RNA secondary structure in replication of Nodamura virus RNA2." To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2009. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.

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3

Wahyuni, Wiwiek Sri. "Variation among cucumber mosaic virus (CMV) isolates and their interaction with plants." Title page, contents and summary only, 1992. http://web4.library.adelaide.edu.au/theses/09PH/09phw137.pdf.

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Includes appendix containing journal publications co-authored by the author. Includes bibliographical references (leaves 130-151). Eighteen strains of Cucumber mosaic virus, including forteen from Australia, two from the USA, and two from Japan were used in this study.

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4

Williams, Rhys Harold Verdon George. "Further studies on the structure and function of the cucumber mosaic virus genome : a thesis submitted to the University of Adelaide, South Australia for the degree of Doctor of Philosophy." 1988, 1988. http://web4.library.adelaide.edu.au/theses/09PH/09phw7261.pdf.

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5

Chen, Baoshan. "Encapsidation of nucleic acids by cucumovirus coat proteins /." Title page, contents and summary only, 1991. http://web4.library.adelaide.edu.au/theses/09PH/09phc5183.pdf.

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6

Shi, Bu-Jun. "Expression and function of cucumoviral genomes." Title page, contents and summary only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phs5546.pdf.

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Bibliography: leaves 104-130. The aim of this thesis is to characterise subgenomic RNAs of cucumoviruses and the functions of their encoding genes. Strains of cucumber mosaic virus (CMV) are classified into two major subgroups (I and II) on the basis of nucleotide sequence homology. The V strain of tomato aspermy virus (V-TAV) and a subgroup I CMV strain (WAII) are chosen to determine whether the 2b genes encoded by these viruses are expressed 'in vivo'. For further investigation of the 2b gene function, cDNA clones of three genomic RNAs of V-TAV are constructed. Using the infectious cDNA clon

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7

Ligat, Julio S. "Pathology and distribution in the host of pea seed-borne mosaic virus." Title page, contents and summary only, 1993. http://web4.library.adelaide.edu.au/theses/09PH/09phl723.pdf.

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Includes bibliographical references (leaves 82-92). Five isolates of pea seed-borne mosaic virus were compared by host range and symptomatology on 16 pisum sativum cultivars lines, 21 lines of Lathyrus and Lens spp. and several indicator species

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8

Hajimorad, Mohammad Reza. "Variation in alfalfa mosaic virus with special reference to its immunochemical properties." Title page, contents and summary only, 1990. http://web4.library.adelaide.edu.au/theses/09PH/09phh154.pdf.

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Includes Appendix listing other publications by the author. Includes bibliographical references (leaves 134-181). Alfalfa mosaic virus was isolated from lucerne (Medicago sativa) plants with a variety of disease symptoms. Experiments showed that each isolate was biologically distinct and that the host range and symptomatology of each isolate was affected by the environmental condition.

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9

Wakeford, Laura 1956. "COMPLEMENTATION BETWEEN TEMPERATURE-SENSITIVE MUTANTS OF POLIOVIRUS." Thesis, The University of Arizona, 1987. http://hdl.handle.net/10150/276556.

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Conditional lethal mutants of poliovirus type 1 (Mahoney) were generated by treatment with the mutagen hydroxylamine. Temperature-sensitive mutants were selected by the replica plating technique at temperatures of 33°C (permissive) and 39°C (restrictive). New mutants were generated to achieve a larger population of mutants and also to generate additional RNA- mutants in this population. These mutants were characterized by two criteria: RNA synthesis and thermal stability. RNA synthesis is measured by the accumulation of labeled uridine incorporation into trichloroacetic acid (TCA) insoluble ma

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10

Sheldon, Candice Claire. "Hammerhead mediated self-cleavage of plant pathogenic RNAs /." Title page, contents and summary only, 1992. http://web4.library.adelaide.edu.au/theses/09PH/09phs544.pdf.

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11

Geering, Andrew D. W. "The epidemiology of cucumber mosaic virus in narrow-leafed lupins (Lupinus angustifolius) in South Australia." Title page, table of contents and summary only, 1992. http://web4.library.adelaide.edu.au/theses/09PH/09phg298.pdf.

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12

Du, Preez Jacques. "The construction of an infectious clone of grapevine virus A (GV A)." Thesis, Link to the online version, 2005. http://hdl.handle.net/10019/1012.

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13

Fosu-Nyarko, John. "Studies on Subterranean clover mottle virus towards development of a gene silencing vector." Thesis, Fosu-Nyarko, John (2005) Studies on Subterranean clover mottle virus towards development of a gene silencing vector. PhD thesis, Murdoch University, 2005. https://researchrepository.murdoch.edu.au/id/eprint/54/.

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Subterranean clover mottle virus (SCMoV) is a positive sense, single-stranded RNA virus that infects subterranean clover (Trifolium subterraneum) and a number of related legume species. The ultimate aim of this research was to investigate aspects of SCMoV that would support its use as a gene silencing vector for legume species, since RNA (gene) silencing is now a potential tool for studylng gene function. The ability of viruses to induce an antiviral defense system is being explored by virus-induced gene silencing (VIGS), in which engmeered viral genomes are used as vectors to introduce genes

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14

Fosu-Nyarko, John. "Studies on Subterranean clover mottle virus towards development of a gene silencing vector." Fosu-Nyarko, John (2005) Studies on Subterranean clover mottle virus towards development of a gene silencing vector. PhD thesis, Murdoch University, 2005. http://researchrepository.murdoch.edu.au/54/.

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Subterranean clover mottle virus (SCMoV) is a positive sense, single-stranded RNA virus that infects subterranean clover (Trifolium subterraneum) and a number of related legume species. The ultimate aim of this research was to investigate aspects of SCMoV that would support its use as a gene silencing vector for legume species, since RNA (gene) silencing is now a potential tool for studylng gene function. The ability of viruses to induce an antiviral defense system is being explored by virus-induced gene silencing (VIGS), in which engmeered viral genomes are used as vectors to introduce genes

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15

Dutta, Ranendra Nath. "Experimental Test of Solitary Wave Theory in Viral Populations." University of Toledo Health Science Campus / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=mco1226950654.

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16

Aubry, Fabien. "Development and applications of a new reverse genetics method for the generation of single-stranded positive-sense RNA viruses." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM5066.

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La génétique inverse est devenue une méthode clé pour la production de virus à ARN génétiquement modifiés et pour comprendre les propriétés cellulaires et biologiques des virus. Cependant les méthodes les plus fréquemment utilisées, basées sur le clonage de génomes viraux complets dans des plasmides, sont laborieuses et imprévisibles. La première partie de cette thèse présente des études sur la mise au point d'un nouveau système de génétique inverse, appelé méthode ISA (Amplicons-Sous génomique-Infectieux), qui permet la génération, en quelques jours, de virus infectieux sauvages et génétiquem

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17

au, J. Fosu@murdoch edu, and John Fosu-Nyarko. "Studies on Subterranean clover mottle virus towards development of a gene silencing vector." Murdoch University, 2005. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20050421.123457.

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Subterranean clover mottle virus (SCMoV) is a positive sense, single-stranded RNA virus that infects subterranean clover (Trifolium subterraneum) and a number of related legume species. The ultimate aim of this research was to investigate aspects of SCMoV that would support its use as a gene silencing vector for legume species, since RNA (gene) silencing is now a potential tool for studylng gene function. The ability of viruses to induce an antiviral defense system is being explored by virus-induced gene silencing (VIGS), in which engmeered viral genomes are used as vectors to introduce genes

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18

Lee, Se Il. "Statistical thermodynamics of virus assembly." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/33900.

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Experiments show that MgSO4 salt has a non-monotonic effect as a function of MgSO4 concentration on the ejection of DNA from bacteriophage lambda. There is a concentration, N0, at which the minimum amount of DNA is ejected. At lower or higher concentrations, more DNA is ejected. We propose that this non-monotonic behavior is due to the overcharging of DNA at high concentration of Mg⁺² counterions. As the Mg⁺² concentration increases from zero, the net charge of ejected DNA changes its sign from negative to positive. N0 corresponds to the concentration at which DNA is neutral. Our theory fits

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19

Terenius, Olle. "Anti-parasitic and anti-viral immune responses in insects." Doctoral thesis, Stockholm : Institutionen för genetik, mikrobiologi och toxikologi, Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-224.

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20

Carneiro, Bruno Moreira [UNESP]. "Estudo in vitro do efeito da interferência por RNA (RNAi) na replicação do vírus da hepatite C." Universidade Estadual Paulista (UNESP), 2013. http://hdl.handle.net/11449/108909.

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Made available in DSpace on 2014-08-27T14:36:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-08-15Bitstream added on 2014-08-27T15:57:02Z : No. of bitstreams: 1 000778124.pdf: 2188391 bytes, checksum: fd262617e1148f5350687c3217aafda3 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>A Hepatite C é a inflamação do fígado causada pela infecção pelo vírus da hepatite C (HCV). Essa inflamação ocorre na maioria das pessoas infectadas pelo vírus e, dependendo da intensidade e tempo de duração,

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21

O'Brien, Siobhan. "Regulation of Cellular and HIV-1 Gene Expression by Positive Transcription Elongation Factor B: A Dissertation." eScholarship@UMMS, 2010. https://escholarship.umassmed.edu/gsbs_diss/528.

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RNA polymerase II-mediated transcription of HIV-1 genes depends on positive transcription elongation factor b (P-TEFb), the complex of cyclin T1 and CDK9. Recent evidence suggests that regulation of transcription by P-TEFb involves chromatin binding and modifying factors. To determine how P-TEFb may connect chromatin remodeling to transcription, we investigated the relationship between P-TEFb and histone H1. We show that P-TEFb interacts with H1 and that H1 phosphorylation in cell culture correlates with P-TEFb activity. Importantly, P-TEFb also directs H1 phosphorylation during Tat transacti

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22

Choudhury, Md Abu Hasnat Zamil. "Population Dynamics of RNA viruses." Thesis, Queensland University of Technology, 2013. https://eprints.qut.edu.au/60866/1/Md._Choudhury_Thesis.pdf.

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Between 50 and 100 million people are infected with dengue viruses each year and more than 100,000 of these die. Dr Choudhury has demonstrated that populations of dengue viruses in individual patients are genetically and functionally very diverse and that this diversity changes significantly at the time of major outbreaks of disease. The results of his studies may inform strategies which will make dengue vaccines far more effective.

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23

Rosskopf, John J. "CIS-acting signals for replication of Nodamura virus RNA1." To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2009. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.

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24

Turner, David Richard. "Protein-RNA interactions in tobacco mosaic virus assembly." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328799.

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25

Lamprecht, Renate Luise. "Molecular characterisation of South African isolates of grapevine fanleaf virus and a new, associated satellite RNA." Thesis, Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/85600.

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Thesis (PhD)--Stellenbosch University, 2013.<br>ENGLISH ABSTRACT: Grapevine fanleaf virus (GFLV) is one of the oldest, most widespread and devastating viruses infecting grapevine, and occurs globally where Vitis vinifera is grown. In South Africa (SA) GFLV is predominant in the Breede River Valley, one of the highest wine producing regions in SA. To date, only three GFLV isolates have been completely sequenced internationally, and limited sequence information is available for SA GFLV isolates. In this study, the first full-length GFLV genome sequence from a South African isolate, GFLV-SA

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26

Visser, Marike. "Small RNA profiling of virus-infected apple plants." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/95828.

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Thesis (PhD)--Stellenbosch University, 2014.<br>ENGLISH ABSTRACT: Apple stem grooving virus (ASGV) is globally associated with latent infection in commercial apple trees. Little is known about this plant-‐virus interaction. This study made use of next-‐generation sequencing to investigate the effect of virus-‐infection on the expression of the different small RNA (sRNA) species namely, miRNAs, nat-‐siRNAs, phasiRNAs, rasiRNAs, tRNA-‐derived sRNAs and vsiRNAs. Broad and narrow size-‐range datasets were generated using sRNA libraries prepared from total and size-‐selected RNA, res

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27

Gnädig, Nina Franziska. "Role of genetic diversity of RNA viruses in viral evolution and pathogenicity." Paris 7, 2012. http://www.theses.fr/2012PA077095.

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Le taux de fréquence de mutation des virus à ARN est très élevé, en raison des erreurs commises par TARN polymerase dépendante de TARN. Par conséquent, une population virale génétiquement diverse est générée, sur la base d'une séquence consensus. Cette population, ou quasi-espèce, se comportent comme une entité unique en terme d'évolution et de sélection. Cet aspect permet aux virus de s'adapter rapidement à de nouveaux environnements. Pendant le première partie de mon travail, je me suis concentrée sur l'étude d'un variant haute fidélité (A372V) et d'un variant basse fidélité (S299T) de la po

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Sleat, D. E. "Packaging and expression of recombinant RNAs." Thesis, University of Liverpool, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382121.

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29

Fedewa, Gregory. "Quantifying Nucleotide Variation in RNA Virus Populations by Next-generation Sequencing." Thesis, University of California, San Francisco, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10936274.

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<p> RNA viruses include several notable human pathogens including HIV, hepatitis C virus, West Nile virus, influenza, and Ebola virus. This group of viruses includes viruses with incredibly diverse genome structures, such as single-stranded genomes, double-stranded genomes, multipart genomes, negative-stranded genomes, and positive-stranded genomes. They also exist as heterogeneous populations that can mutate and rapidly evolve due to their error-prone polymerases. These errors then accumulate as they are passed down through generation. They can, therefore, be used as a historical marker for g

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30

Collins, Fergal M. "Investigation of the morbillivirus large protein by reverse genetics." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326404.

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31

Cheung, Mei-sze, and 張美思. "The application of an Epstein-Barr Virus specific antisense ribozyme for the in vitro suppression of EBNA-1 and LMP-1 expression." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B42577056.

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32

Carneiro, Bruno Moreira. "Estudo in vitro do efeito da interferência por RNA (RNAi) na replicação do vírus da hepatite C /." São José do Rio Preto, 2013. http://hdl.handle.net/11449/108909.

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Orientador: Paula Rahal<br>Banca: Clarice Arns<br>Banca: João Pessoa Araújo Junior<br>Banca: Maurício Lacerda Nogueira<br>Banca: Cristiane Damas Gil<br>Resumo: A Hepatite C é a inflamação do fígado causada pela infecção pelo vírus da hepatite C (HCV). Essa inflamação ocorre na maioria das pessoas infectadas pelo vírus e, dependendo da intensidade e tempo de duração, pode levar à cirrose e câncer do fígado. No momento não existem vacinas eficazes e o tratamento convencional com peg-IFN e ribavirina tem eficácia bastante limitada e efeitos colaterais graves. Terapias moleculares utilizando a RNA

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33

Dunn, Ewan Frazer. "Development of a reverse genetics system to investigate Bunyamwera virus RNA synthesis." Thesis, University of Glasgow, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343641.

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34

McCulley, Anna. "Primer selection of E. coli tRNALys,3 by human immunodeficiency virus type-1." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2007. https://www.mhsl.uab.edu/dt/2008r/mcculley.pdf.

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35

Tanov, Emil Pavlov. "The identification of biologically important secondary structures in disease-causing RNA viruses." University of the Western Cape, 2012. http://hdl.handle.net/11394/4562.

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Magister Scientiae - MSc<br>Viral genomes consist of either deoxyribonucleic acid (DNA) or ribonucleic acid (RNA). The viral RNA molecules are responsible for two functions, firstly, their sequences contain the genetic code, which encodes the viral proteins, and secondly, they may form structural elements important in the regulation of the viral life-cycle. Using a host of computational and bioinformatics techniques we investigated how predicted secondary structure may influence the evolutionary dynamics of a group of single-stranded RNA viruses from the Picornaviridae family. We detected sign

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36

Chong, Jean-Leon. "Functional characterization of Ded1p, a DExD/H box RNA helicase, in saccharomyces cerevisiae." The Ohio State University, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=osu1092284292.

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37

Palmer, William Hunt. "Evolution and genetics of antiviral immunity in Drosophila." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31557.

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Virus-host interactions determine virus transmissibility and virulence, and underlie coevolution that shapes interesting biological phenomena such as the genetic architecture of host resistance and host range. Characterization of the virus factors that exert selective pressure on the host, and the host genes which underlie resistance and adaptation against viruses will help to define the mechanistic pathways embroiled in host-virus coevolution. In this thesis, I describe the viral causes and host consequences of host-virus coevolution. These include genomic signatures consistent with antagonis

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38

Pickett, Brett E. "The contribution of different mechanisms of viral sequence variation to the evolution of positive-sense single-stranded RNA viruses." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2010. https://www.mhsl.uab.edu/dt/2010p/pickett.pdf.

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Hampson, J. "A study of the genetics and growth of a tripartite RNA virus using ts mutants." Thesis, University of Warwick, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380288.

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Bhatt, Samir. "Statistical analysis of natural selection in RNA virus populations." Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:64341c38-f09e-48ed-84e8-7ab9f171a753.

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A key goal of modern evolutionary biology is the identification of genes or genome regions that have been targeted by natural selection. Methods for detecting natural selection utilise the information sampled in contemporary gene sequences and test for deviation from the null hypothesis of neutrality. One such method is the McDonald Kreitman test (MK test), which detects the the molecular 'footprint' left by natural selection by considering the frequency of observed mutations within the sampled population. In this thesis I investigate the applicability of the MK test to viral populations and d

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41

Clinch, Barry F. "A study of methods in reverse genetics for the rescue of influenza virus subgenomic RNA." Thesis, University of Reading, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244944.

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42

Stenbak, Carolyn Rinke. "Foamy virus polymerase : enzymatic activities and assembly /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/11510.

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Song, Rujun. "Dimerization of human immunodeficiency virus type 1 genome : dimer maturation process and role of the 5' untranslated region in dimerization." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111918.

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Human Immunodeficiency Virus type I genome consists of two identical RNA molecules that are non-covalently linked to form a dimer. HIV-1 immature and mature genomic RNA (gRNA) dimers were found in protease defective (PR -) and wild type virions, respectively, and the 5'untranslated region (5' UTR) was shown to play key roles during the genome dimerization process; but the dimerization mechanism still remains to be clarified My research project is to characterize the dimerization process and the role of 5' UTR in genome dimerization in virions produced by tissue culture cells. I'll firstly show

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44

Palmer, Matthew T. "The influence of retroviral codon usage on the acquisition of the tRNA used to prime reverse transcription." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2006. https://www.mhsl.uab.edu/dt/2007r/palmer.pdf.

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45

Wadsworth, Santiago. "Genetic and biochemical study of P15, the RNA silencing suppressor of Peanut clump virus." Strasbourg, 2010. http://www.theses.fr/2010STRA6233.

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Le RNA silencing est un mécanisme de régulation négative de l’expression des gènes, retrouvé chez la plupart des organismes eucaryotes et basé sur des interactions d’ARN séquence-spécifiques. Il est déclenché par de l’ARN double brin qui est découpé par Dicer en de petits ARNs de 21 ‡ 24nt, nommés short-interfering (si)RNAs ou microRNAs. Un brin du duplex est incorporé dans un complexe appelé RNA-induced silencing complex (RISC), pour guider le clivage endonucléolytique ou l’inhibition traductionnelle d’ARNm présentant une homologie de séquence. Chez les plantes, le RNA silencing joue un rôle

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46

Phan, Ngoc Minh Hien. "Perusing peripatetic pathogenic viruses: Hepatitis B virus and severe acute respiratory syndrome coronavirus 2." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/226107/1/Ngoc%20Minh%20Hien_Phan_Thesis.pdf.

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This project characterised the genetic diversity of hepatitis B virus (HBV) and SARS-CoV-2, which reflects viral evolution, and drives transmission, viral pathogenesis, and clinical outcomes. Genomes and coding genes of these viruses were analysed using next-generation sequencing, bioinformatic tools and publicly available viral sequences. HBV nucleotide diversity was identified amongst HBV sequences from Australian and non-Australian blood donors. In addition, the frequency of HBV mutants circulating in Southeast Asia, Australia and New Zealand was identified. Europe and East Asia were shown

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Chen, Kuang-Yu. "Mechanistic study and prediction of influenza A virus genetic reassortment." Thesis, Université de Paris (2019-....), 2019. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=4762&f=29825.

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La nature segmentée du génome des virus de la grippe A (IAV) permet une évolution rapide par réassortiment génétique. Bien que le nombre théorique de génotypes issus d'un réassortiment entre deux virus soit de 256 (28), la panoplie complète des différents génotypes n'a jamais été observée et certains gènes ont tendance à co-ségréger, suggérant que le réassortiment génétique est biaisé. Cependant, à ce jour, les contraintes qui façonnent le réassortiment génétique restent largement méconnues. L'objectif de mon projet est de progresser dans la compréhension des règles sous-jacentes au réassortim

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Penzes, Zoltan. "Defective replicating RNAs of coronavirus infectious bronchitis virus : investigation of replication and genome packaging signals." Thesis, University of Hertfordshire, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283879.

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Neuman, Benjamin. "Use of defective-RNAs containing reporter genes to investigate targetted recombination in avian infectious bronchitis virus." Thesis, University of Reading, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367694.

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Khidr, Yehia. "Development of a strategy to induce RNA-silencing in squash against virus diseases by genetic transformation." [S.l. : s.n.], 2007. http://nbn-resolving.de/urn:nbn:de:bsz:100-opus-1963.

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