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Gotowe bibliografie tematyczne / Saccharomyces cerevisiae genome codes

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Gotowa bibliografia na temat „Saccharomyces cerevisiae genome codes”

Autor: Grafiati

Data publikacji: 6 września 2023

Data aktualizacji: 7 września 2023

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Rozprawy doktorskie na temat "Saccharomyces cerevisiae genome codes"

1

Rowley, Neil K. "Studies on the Saccharomyces cerevisiae genome." Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361615.

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2

Greig, Duncan. "Sex, species and Saccharomyces cerevisiae." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301401.

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Novarina, D. "MECHANISMS PRESERVING GENOME INTEGRITY IN SACCHAROMYCES CEREVISIAE." Doctoral thesis, Università degli Studi di Milano, 2013. http://hdl.handle.net/2434/215589.

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The integrity of the genome is continuously jeopardized by endogenous reactive byproducts of cellular metabolism and genotoxic insults by environmental agents, as well as by the DNA transactions (replication, transcription and recombination) required for cell survival and proliferation. Failure of the mechanisms deputed to the maintenance of genome integrity leads to genome instability, which is a hallmark of cancer and a driving force of tumorigenesis. To fully understand the mechanisms leading to genome instability and the cellular pathways counteracting them, three basic tasks must be achie

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SHANMUGAN, MUTHU KUMAR. "EXPLORING GENOME INTEGRITY PATHWAYS IN SACCHAROMYCES CEREVISIAE." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/229912.

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Genomic DNA is under constant attack from both endogenous and exogenous DNA damaging agents like reactive oxygen species which include O2, H2O2, OH, reactive carbonyl species, alkylating agents such as estrogen and cholesterol metabolites, radiations (like UV, x-rays and gamma rays) and mutagenic chemicals. Moreover, threats to DNA integrity can also come from DNA metabolism such as replication, transcription and recombination. In order to survive and faithfully transmit the genetic material to the progeny, cells must detect the damage and activate repair mechanisms and, if the damage cannot b

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Bleackley, Mark Robert. "Transition metal tolerance and the Saccharomyces cerevisiae genome." Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/30821.

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Transition metal ions are essential nutrients to all forms of life. Iron, copper, zinc, manganese, cobalt and nickel all have unique chemical and physical properties that make them attractive molecules for use in biological systems. Many of these same properties that allow these metals to provide essential biochemical activities and structural motifs to a multitude of proteins including enzymes and other cellular constituents also leads to a potential for cytotoxicity. Organisms have been required to evolve a number of systems for the efficient uptake, intracellular transport, protein loadi

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Minchell, Nicola E. "DNA topological stress during DNA replication in Saccharomyces cerevisiae." Thesis, University of Sussex, 2019. http://sro.sussex.ac.uk/id/eprint/81222/.

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DNA topological stress impedes normal DNA replication. If topological stress is allowed to build up in front of the replication fork, the fork rotates to overcome the stress, leading to formation of DNA pre-catenanes. The formation of DNA pre-catenanes is therefore a marker of DNA topological stress. In this study, I have examined how transcription linked DNA topological stress impacts on fork rotation and on endogenous DNA damage. Transcription, similar to replication, affects the topology of the DNA; and collision between the two machineries is likely to lead to high levels of DNA topologica

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7

Cook, Kristen. "Regulation of Genome-Wide Transcriptional Stress Responses in Saccharomyces cerevisiae." Thesis, Harvard University, 2011. http://dissertations.umi.com/gsas.harvard:10032.

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In response to osmotic shock in Saccharomyces cerevisiae the MAP kinase Hog1 coordinates a large-scale transcriptional stress response, rapidly producing hundreds of copies of specified transcripts. Many of the most highly induced genes are bound and regulated by a transcription factor, Sko1, but lack the canonical binding site for this factor. We use ChIP-seq to demonstrate a stress-specific binding mode of Sko1. In stress, Sko1 binds to promoters in close proximity to Hog1, and another Hog1-regulated transcription factor, Hot1. This mode of Sko1 binding requires the physical presence of

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8

Coissac, Éric. "Analyse structurale et fonctionnelle du genome de la levure saccharomyces cerevisiae." Paris 6, 1996. http://www.theses.fr/1996PA066520.

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Dans le cadre d'une collaboration internationale, la sequence nucleotidique du genome de la levure saccharomyces cerevisiae a ete entierement determinee. Au sein de ce projet, nous avons sequence un fragment d'adn de 39411 paires de bases correspondant aux regions telomerique et subtelomerique gauches du chromosome vii. Cette region comporte dix-huit phases ouvertes de lectures longues de plus de cent codons et une de soixante-seize. Parmi elles, six correspondent a des genes precedemment identifies : adh4, fzf1, hxk2, rtg2, hfm1 et pde1. La deletion de cinq autres a ete realisee (ygl257c, ygl

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9

Teixeira, Maria Teresa. "Organisation du noyau et analyse fonctionnelle du genome de saccharomyces cerevisiae." Paris 11, 2000. http://www.theses.fr/2000PA112033.

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La structure du noyau semble etre hautement organisee : de nombreux facteurs nucleaires sont adresses a des domaines discrets, en concordance avec leur role localise. Cette regionalisation spatiale et fonctionnelle est particulierement bien etablie dans le cas du nucleole, site d'assemblage des sous-unites ribosomiques et dans le cas du pore nucleaire, site du trafic nucleo-cytoplasmique. Ce travail de these a pour but de participer a la caracterisation moleculaire de certains constituants du noyau impliques dans cette organisation fonctionnelle en prenant comme modele experimental la levure s

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10

Amai, Takamitsu. "Development of genome editing technology of mitochondrial DNA in Saccharomyces cerevisiae." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263707.

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