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1

Daksha, Shraddha, Shakti Bhan Khanna, Kiranabala Dash, Shuaib Zaidi, and Vikas Kashyap. "Asymptomatic adult type IV sacrococcygeal teratoma: incidental diagnosis in a case of subfertility." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 13, no. 11 (2024): 3405–8. http://dx.doi.org/10.18203/2320-1770.ijrcog20243219.

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Sacrococcygeal teratomas (SCT) are rare congenital tumours that are even more uncommon when present in adulthood. They are derived from residual stem cells in the presacral space that differentiate into clusters of somatic cells. We present a case of asymptomatic sacrococcygeal teratoma (SCT) in 28 years old female, presented for subfertility workup and diagnosed incidentally while investigating for it. Preoperative diagnosis was complex cystic lesion involving presacral space with possibility of dermoid, epidermal, or cystic presacral hamartoma. The mass was completely excised through abdomen
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Nasreen, Ali* &. Sunil Kumar Agarwalla. "MALIGNANT SACROCOCCYGEAL TERATOMA IN AN INFANT-RARE CASE REPORT." Indian Journal of Medical Research and Pharmaceutical Sciences 4, no. 6 (2017): 28–30. https://doi.org/10.5281/zenodo.810281.

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Sacrococcygeal teratoma(SCT) is a tumour located at the base of coccyx (tail bone) and thought to be derived from embryonic germ cell layers.The tumors present mostly in infancy. Modern imaging techniques may be helpful to detect the extent of mass. Here we report a case of 1 year old female baby who presented to the emergency department of MKCG with complains of anuria and constipation for last 4 days.The abdomen was distended.USG abdomen and pelvis and CECT abdomen showed mass in the sacro coccygeal area.FNAC confirmed the diagnosis as MALIGNANT GERM CELL SACROCOCCYGEAL TERATOMA. Most sacroc
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Vaitkevičiūtė, Marija, Saulė Kržčonavičiūtė, Eglė Savukynė, Eglė Machtejevienė, and Ieva Rubavičiūtė. "Antenatalinė kryžkaulio-uodegikaulio cistinės teratomos diagnostika. Klinikinis atvejis ir literatūros apžvalga." Lithuanian Obstetrics & Gynecology 25, no. 3 (2022): 240–45. http://dx.doi.org/10.37499/lag.993.

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Kryžkaulio-uodegikaulio teratoma (angl. sacrococcygeal teratoma – SCT) yra įgimtas embrioninis navikas, dažniau diagnozuojamas moteriškosios lyties vaisiams ir naujagimiams. Šiame straipsnyje aprašomas retas antenatalinis vaisiaus kryžkaulio-uodegikaulio cistinės teratomos klinikinis atvejis, nustatytas 2022 m., Lietuvos sveikatos mokslų universiteto ligoninės Kauno klinikų (toliau – Kauno klinikų) Akušerijos ir ginekologijos klinikoje. Literatūros apžvalgoje aprašoma kryžkaulio-uodegikaulio cistinės teratomos diferencinė diagnozė. Ypatingas dėmesys skiriamas terminalinės mielocistocelės ir SC
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4

Sabir, Wirya N., Sasan M. Ahmed, Karzan M. Hasan, et al. "Giant sacrococcygeal teratoma in an infant: a case report with a literature review." Annals of Medicine & Surgery 85, no. 11 (2023): 5666–69. http://dx.doi.org/10.1097/ms9.0000000000001274.

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Introduction and importance: A sacrococcygeal teratoma (SCT) is a rare embryonal tumor that emerges in the sacrococcygeal area. It affects one in every 35 000–40 000 live births. Herein, we report a case of a substantial SCT in a neonate. Case presentation: A neonate girl from consanguineous parents was delivered by cesarean section with a large mass (18×17 cm) in the sacrococcygeal area. The baby’s birth weight was 5 kg, of which 2.5 belonged to the mass. The vital signs were within normal ranges and she had weak movement with bluish peripheral limbs. Oxygen saturation was around 85% for a sh
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Shahjouei, Shima, Sara Hanaei, Farideh Nejat, Maryam Monajemzadeh, and Mostafa El Khashab. "Sacrococcygeal teratoma with intradural extension: case report." Journal of Neurosurgery: Pediatrics 15, no. 4 (2015): 380–83. http://dx.doi.org/10.3171/2014.10.peds1445.

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Intradural sacrococcygeal teratoma (SCT) is a rare entity that has been reported in only a few cases previously. The authors present the case of a 2-week-old, otherwise healthy neonate with a mass in the buttock. The imaging findings and the high level of serum alpha-fetoprotein were highly suggestive of SCT. On operation the authors found intradural extension of the teratoma. The lesion was managed successfully without any remaining sequelae. The authors briefly review the currently proposed etiology regarding teratoma formation and the intradural extension of SCT.
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Kundal, VK, A. Jadhav, A. Gupta, A. Shukla, V. Chaturvedi, and R. Kundal. "Sacrococcygeal Teratoma: Experience with 36 Patients in a Teritiary Care Hospital." Journal of Nepal Paediatric Society 35, no. 1 (2015): 89–93. http://dx.doi.org/10.3126/jnps.v35i1.10945.

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Introduction: Sacrococcygeal teratomas (SCT) are the most common solid tumours in the neonatal period, originate from embryonic totipotent cells. Most of them are benign however some that present later in life and have major intra-pelvic component have greater malignant potential. Complete surgical excision provides an excellent prognosis. The aim of this study was to describe the clinical profile, age of presentation, sex distribution, diagnostic evaluation and management of children with a histological confirmed diagnosis of sacrococcygeal teratoma.Material and Methods: Patients with histolo
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7

M, Parvez, Paul S. K, Muaz S. S. A, Rahman A, Hasan S, and Alam J. "Childhood Sacrococcygeal Teratoma: A Histopathological Study." Saudi Journal of Medical and Pharmaceutical Sciences 8, no. 12 (2022): 809–12. http://dx.doi.org/10.36348/sjmps.2022.v08i12.014.

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Background: Sacrococcygeal teratoma (SCT) is a relatively uncommon germ cell tumor and affecting neonates, infants as well as children with a female preponderance. Age is an important predictor of malignancy in SCT. Early diagnosis and management can provide better outcome. Histologically most of the cases are benign in nature. Aim: Since there have been paucity of sufficient studies in this field in Bangladesh. The present study was carried out to describe in various clinicopathological features and histopathological findings of SCT patients. Materials and Methods: The study included 66 patie
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8

Ritonga, Budiman, Kadek Deddy Ariyanta, and I. Made Darmajaya. "Management mature sacrococcygeal teratoma: a case report." International Journal of Research in Medical Sciences 7, no. 10 (2019): 3891. http://dx.doi.org/10.18203/2320-6012.ijrms20194195.

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Mature sacrococcygeal teratoma (SCT) are uncommon neoplasm comprised of mixed elements derived from three germ layers. They attract attention because of their gross appearance and bizarre histology. Tumor of the sacrococcygeal region, referred to as sacrococcygeal teratomas (SCTs) in most reports, generally present in two distinct fashions: neonates with large predominately external lesions, which are detected in utero or at birth and are rarely malignant; and older infants and children who present with primarily hidden pelvic tumors with a much higher rate of malignancy. Sacrococcygeal terato
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9

Saha, Laxmi, Ola Haidar Wahbi, Evelio Alberto Ramos, Yasmin Abozenah, Maha Ghorabah, and Martin Corbally. "Case Report of a Rapidly Growing Sacrococcygeal Teratoma: A Planned Preterm Cesarean Delivery May Improve Fetal Outcome." Journal of the Bahrain Medical Society 34, no. 2 (2022): 57–61. http://dx.doi.org/10.26715/jbms.34_2022_2_9.

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Sacrococcygeal teratoma (SCT) is the most commonly diagnosed congenital tumor during the neonatal period. The outcome of SCT is dependent on the growth rate, the presence of solid components in cancer, and the presence or absence of high flow cardiac involvement of the fetus. This case report presents the management and outcome of a pregnant woman carrying a fetus with a rapidly growing SCT. Confirmation of diagnosis was based on the universal prenatal ultrasound examination standards. Eventually, the patient delivered a girl weighing 2.9 kg, including the neoplasm, by a planned Cesarean secti
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10

Cui, Shengjie, Jing Han, Binny Khandakar, et al. "Recurrent Adult Sacrococcygeal Teratoma Developing Adenocarcinoma: A Case Report and Review of Literatures." Case Reports in Pathology 2021 (November 27, 2021): 1–6. http://dx.doi.org/10.1155/2021/5045250.

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Sacrococcygeal teratomas (SCT) are most commonly seen in infants and children but are rare in adults. Most adult SCT are benign and mature with a minority of tumors having immature components or overt malignancy. Here, we report a 65-year-old female with a SCT developing adenocarcinoma. The patient was diagnosed with benign sacrococcygeal cystic teratoma on her initial hospital visit and was treated with surgical resection. She was followed up postoperatively and was noted to have a markedly elevated CA 19-9 level 13 months after the surgery. Radiological and clinical examination revealed thic
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11

Zhou, Pengfei, Shiju Liu, Huiju Yang, Yaxin Jiang, Xiang Liu, and Dianwen Liu. "Signet ring cell carcinoma arising from sacrococcygeal teratoma: a case report and review of the literature." Journal of International Medical Research 47, no. 5 (2019): 2234–39. http://dx.doi.org/10.1177/0300060519831574.

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We report here a rare case of adult sacrococcygeal teratoma (SCT) that was pathologically diagnosed as signet ring cell carcinoma (SRCC). A 26-year-old man complained of lower abdominal distension and discomfort and difficulty in urinating, and he was admitted to our hospital. Pelvic magnetic resonance imaging showed multiple oval, solid-cystic masses around the anterior sacrococcygeal region that measured approximately 96 × 114 × 89 mm. Magnetic resonance imaging also showed irregular cysts around the posterior sacrococcygeal region that measured approximately 34 × 72 × 60 mm. The preliminary
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Zhong, Qiang, Qizhu Zhang, Ziwen Xiao, and Hao Zhang. "Laparoscopic transabdominal-sacrococcygeal approach for resection of Altman type III sacrococcygeal teratoma in adult women: A case report." Medicine 103, no. 17 (2024): e37887. http://dx.doi.org/10.1097/md.0000000000037887.

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Introduction: Adult sacrococcygeal teratoma (SCT) is a rare disease that is not easily detected or easily missed, and its treatment is based on surgery, including transabdominal, transsacral, or a combination of both, but there are no clear guidelines for diagnosis and treatment. We share a case of Altman type III SCT in order to provide more reference protocols for the diagnosis and treatment of adult SCT, and more importantly to increase our understanding of different types of SCT cases in adults. Patient concerns: Our patient was a 31-year-old adult woman who underwent complete surgical res
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13

Sinha, Shalini, Yogesh Kumar Sarin, and Vidyanand P. Deshpande. "Neonatal Sacrococcygeal Teratoma: Our Experience with 10 Cases." Journal of Neonatal Surgery 2, no. 1 (2013): 4. http://dx.doi.org/10.47338/jns.v2.16.

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Aim: To analyse the outcome of neonatal sacrococcygeal teratomas (SCT) in our setup.Materials and Methods: Hospital records of 10 neonates, who were operated for SCT during 14 years time period, were retrieved and analysed. Letters were sent to 6 parents/ caretakers of children who were lost to follow up; none of them responded.Results: Seven girls and 3 boys with a mean age of 9 days (range 1- 30 days) underwent excision of SCT in the neonatal period. Antenatal pickup rates were poor (2/10). Two patients presented with tumor rupture. Though all had an obvious mass at birth, only half of them
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Khan, Suhail M., Azhar A. Khan, Anzeen N. Kanth, Aymen M. Khan, and Irfita N. Kanth. "A sacrococcygeal teratoma-a rare entity among adult males: a case report and review of literature." International Surgery Journal 8, no. 5 (2021): 1646. http://dx.doi.org/10.18203/2349-2902.isj20211850.

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Sacrococcygeal teratoma (SCT) is derived from embryonic germ cell layers and is one of the commonest tumours in infants. It is the most commonly occurring solid congenital tumours in the foetus and the new born. It is very rare in adults with less than a hundred cases documented in literature, with even rarer cases of male presentation. We report a case of a 26-year-old adult male presenting with a sacrococcygeal teratoma who was treated in our hospital along with its literature review.
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Aballa, Najoua, Houssine Ghannane, and Mohamed Oulad Saiad. "A Rare Case of Sacrococcygeal Teratoma With Medullar Invasion." Iranian Journal of Neurosurgery 6, no. 4 (2020): 229–32. http://dx.doi.org/10.32598/irjns.6.4.8.

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Background and Importance: Sacrococcygeal Teratoma (SCT) with medular invasion is rare. Case Presentation: We report a case of an 11-month male infant, with no prenatal history of any abnormality, presenting since birth, a mass in the buttock extended to retrorectum associated with a right side hypotonic limb and monoplegia. Medullar and abdominal pelvic Magnetic Resonance Imaging (MRI) showed a sacrococcygeal tissue mass and intradural lumbosacral invasion with a high level of alpha-fetoprotein. Surgical excision was done successfully with an uneventful follow-up. Conclusion: Despite of the i
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Solanki, Shailesh. "Diagnostic Dilemma in Ruptured Cystic Sacrococcygeal Teratoma: A Case Report." Journal of Neonatal Surgery 7, no. 4 (2018): 47. http://dx.doi.org/10.21699/jns.v7i4.799.

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Sacrococcygeal teratoma (SCT) is the most common tumor of the newborn. Diagnosis is clinical and frequently straightforward. However, varied presentations can occasionally result in a diagnostic dilemma. We present a case of ruptured cystic Altman Type 1 SCT along with pertinent review of literature. The purely cystic variant of SCT is rare in itself and presenting as a ruptured lesion added to the dilemma in diagnosis and management.
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Kennedy, A., P. Woodward, and J. L. Byrne. "OP27.09: Prenatal diagnosis of sacrococcygeal teratoma (SCT) rupture." Ultrasound in Obstetrics & Gynecology 44, S1 (2014): 150–51. http://dx.doi.org/10.1002/uog.13905.

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Mondal, Monojit, Biswajit Biswas, Atanu Roy, et al. "A neglected case of Sacrococcygeal teratoma in a neonate." Asian Journal of Medical Sciences 6, no. 2 (2014): 108–10. http://dx.doi.org/10.3126/ajms.v6i2.10448.

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Sacrococcygeal teratoma (SCT), although rare, is the most common congenital neoplasm in neonates. A mass in the sacrococcygeal region at the time of birth is the usual presentation. Routine antenatal abdominal ultrasound of mother can detect almost all the cases. The prognosis is favorable when diagnosis is done antenatally and proper management is instituted soon after the baby is born. Presented herein a 2 days old neonate with a neglected SCT who died unfortunately due to massive bleeding from the tumor. A brief review of the literature has been presented to make everyone aware of the condi
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Monojit Mondal, Biswajit Biswas, Atanu Roy, et al. "A neglected case of Sacrococcygeal teratoma in a neonate." Asian Journal of Medical Sciences 6, no. 2 (2014): 108–10. https://doi.org/10.71152/ajms.v6i2.3506.

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Sacrococcygeal teratoma (SCT), although rare, is the most common congenital neoplasm in neonates. A mass in the sacrococcygeal region at the time of birth is the usual presentation. Routine antenatal abdominal ultrasound of mother can detect almost all the cases. The prognosis is favorable when diagnosis is done antenatally and proper management is instituted soon after the baby is born. Presented herein a 2 days old neonate with a neglected SCT who died unfortunately due to massive bleeding from the tumor. A brief review of the literature has been presented to make everyone aware of the condi
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Sharma, Snigdha, Arti Sharma, and Madhukar Maletha. "High risk pregnancy with sacrococcygeal teratoma." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 13, no. 10 (2024): 2933–35. http://dx.doi.org/10.18203/2320-1770.ijrcog20242836.

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Sacrococcygeal teratoma (SCT) is the most common tumor of the newborn period. Most cases are diagnosed prenatally during ultrasound imaging. If fetal hydrops develops, urgent intervention is done to minimize fetal morbidity (or mortality). Management depends on fetal lung maturity and tumor size. Most cases are benign and require only minimal intervention. Once fetal maturity is achieved at 37 weeks, scheduled delivery is planned. Complete resection of tumor including coccyx is vital to prevent malignant recurrence. Strict follow up and AFP monitoring is important. Small percentage become mali
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Kornete, Anna, Diana Bokucava, and Natalija Vedmedovska. "Fetal Sacrococcygeal Teratoma: A Case Report of a Giant Tumor with an Excellent Outcome." Acta medica Lituanica 30, no. 2 (2023): 13. http://dx.doi.org/10.15388/amed.2023.30.2.13.

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Sacrococcygeal teratoma (SCT) occurs in approximately 1 per 20,000–40,000 births and is the most frequently encountered fetal teratoma, with 75% of cases observed in female fetuses. SCT can be detected on ultrasound as early as the first trimester, presenting as a large mass originating from the sacrococcygeal area, with or without an intrapelvic component. The prenatal course for most fetuses with SCT is generally uneventful, with only a few cases experiencing obstetric and fetal complications. We present the case of a 19-year-old woman who was in good health and had no relevant family or med
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Abouzeid, Amr Abdelhamid, Shaimaa Abdelsattar Mohammad, Mohammed Elsherbeny, Nehal A. Radwan, and Osama El-Naggar. "Preoperative Grading of Sacrococcygeal Teratoma: A Roadmap to Successful Resection." Journal of Neonatal Surgery 6, no. 4 (2017): 75. http://dx.doi.org/10.21699/jns.v6i4.627.

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Purpose: to include the most relevant preoperative imaging features of sacrococcygeal teratoma (SCT) in a grading system that would provide guidance to surgeons during excision of such rare tumors.Patients and Methods: The medical records of patients with SCT, who were managed at our hospital during the period 2009 through 2016, were retrospectively reviewed. Only cases of SCT with available preoperative cross-sectional imaging studies (MRI and/or CT scans) were included in the study. The preoperative imaging features were correlated to the operative and pathological findings.Results: The stud
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Şahinoğlu, Zeki, Ayşenur Cerrah Celayir, Mehmet Reşit Asoglu, and Nahit Özcan. "Type IV Sacrococcygeal Teratoma Associated with Urogenital Sinus: Difficulties in the Prenatal Differential Diagnosis." Journal of Neonatal Surgery 2, no. 1 (2013): 9. http://dx.doi.org/10.47338/jns.v2.21.

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Sacrococcygeal teratoma (SCT) is being more often detected due to availability of prenatal ultrasonography. Type IV SCT could be misdiagnosed as cloacal abnormalities due to the pelvic midline cystic mass associated with renal malformations and obstructive uropathy during the pregnancy. We discuss difficulties in the prenatal differential diagnosis of SCT and urogenital sinus in a 26-year-old pregnant woman, admitted to our prenatal diagnosis centre for a detailed US for a pre-sacral mass.
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Shalalfa, Neveen, Shatha Wajeeh, Wael Amro, Tasneem Farakhna, Malak Addase, and Javid Mohammadzadeh Azarabadi. "Large neonatal sacrococcygeal teratoma in rural Palestine: A case report." Turkish Journal of Pediatric Surgery 38, no. 3 (2024): 116–20. https://doi.org/10.62114/jtaps.2024.28.

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The majority of solid tumors in newborns are sacrococcygeal teratomas (SCTs). These tumors originate in the sacrococcygeal region and contain tissue from all three germ layers. Nearly one in every 35,000 to 40,000 live births may be affected. Although the tumor is typically benign, the likelihood of malignant progression increases with the increasing age. The development of a mature teratoma can be attributed to either a pathological transformation of primordial germ cells or the development of a single germ cell tumor following the completion of the first phase of meiosis and the failure of m
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Sliepov, O. K., O. V. Perederii, N. Y. Skrypchenko, V. V. Kotsovsky, O. P. Hladyshko, and G. O. Grebinichenko. "The first intravital case of diagnosis and treatment of a giant teratoma of the sacrococcygeal area, which exceeded the body weight of a newborn on 1.5 times." Paediatric Surgery. Ukraine, no. 3(80) (September 28, 2023): 92–99. http://dx.doi.org/10.15574/ps.2023.80.92.

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Purpose - is to analyze and present the experience of perinatal diagnosis and treatment of giant terato-dermoid tumor (TDT) of the sacrococcygeal area, which exceeded the body weight of a newborn on 1.5 times. Clinical case. The article presents a unique clinical case of a giant teratoma of the sacrococcygeal area (SCT), which exceeded the weight of a newborn child on 1.5 times. Features of perinatal support, hypoxic-ischemic damage of internal organs, and surgical intervention for giant SCT in a premature low-weight newborn child are described, which are important elements of optimizing the t
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Tharveen Nair Chandrasekaran, Jia Yee Pwi, and Bhuwaneswaran Vijayam. "Sacrococcygeal Teratoma: Tales of the “Tailbone” Tumour in a Newborn." Journal of Health and Quality of Life 3, no. 1 (2024): 55–63. http://dx.doi.org/10.37934/jhqol.3.1.5563.

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Sacrococcygeal teratoma (SCT) is a rare tumour with a low incidence, but it is the most common extragonadal tumour in the newborn. It occurs at the base of the coccyx (tailbone) and is derived from embryonic germ cell layers. Although the majority are benign in nature, they are associated with significant morbidity and mortality for the mother and the foetus. A multidisciplinary approach is needed where an accurate early diagnosis should be made antenatally, leading to anticipation of complications during intrapartum for the mother and foetus, and ultimately early, complete surgical excision o
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Chandrasekaran, Tharveen Nair, Jia Yee Pwi, and Bhuwaneswaran Vijayam. "Sacrococcygeal Teratoma: Tales of the “Tailbone” Tumour in a Newborn." Journal of Health and Quality of Life 3, no. 1 (2025): 55–62. https://doi.org/10.37934/jhqol.3.1.5562a.

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Sacrococcygeal teratoma (SCT) is a rare tumour with a low incidence, but it is the most common extragonadal tumour in the newborn. It occurs at the base of the coccyx (tailbone) and is derived from embryonic germ cell layers. Although the majority are benign in nature, they are associated with significant morbidity and mortality for the mother and the foetus. A multidisciplinary approach is needed where an accurate early diagnosis should be made antenatally, leading to anticipation of complications during intrapartum for the mother and foetus, and ultimately early, complete surgical excision o
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Maiso Fred, Gamubaka Richard, Namugga Brenda, Moses Elaju, and Abingwa John Patrick. "Defying the Odds: Successful surgical management of a rare intrapelvic sacrococcygeal teratoma in Eastern Uganda." International Journal of Science and Research Archive 15, no. 3 (2025): 1723–27. https://doi.org/10.30574/ijsra.2025.15.3.1800.

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Sacrococcygeal teratomas (SCTs) are the most common congenital tumours in neonates, typically presenting as external masses at birth. We present a rare case of a predominantly intrapelvic SCT in a one-month-old female infant from rural eastern Uganda. The child was referred with a progressively enlarging sacrococcygeal mass that caused anal deviation and difficulty in defecation. Clinical evaluation and imaging suggested a presacral mass without distant spread. Surgical exploration via a posterior sagittal approach revealed a solid intrapelvic tumour tightly adherent to the posterior rectal wa
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Konno, Hiroko, Oluwateniayo O. Okpaise, Lourenço Sbragia, Gabriele Tonni, and Rodrigo Ruano. "Perinatal Outcomes of Intrauterine Interventions for Fetal Sacrococcygeal Teratoma Based on Different Surgical Techniques—A Systematic Review." Journal of Clinical Medicine 13, no. 9 (2024): 2649. http://dx.doi.org/10.3390/jcm13092649.

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Background: This study aims to evaluate the outcomes of fetal sacrococcygeal teratoma (SCT) submitted to prenatal interventions. Methods: We performed a systematic literature review of fetal SCT patients and compared the outcomes between open fetal surgery and percutaneous intervention. In addition, we also compared the results of SCT fetuses who did not undergo any surgical intervention (NI). Results: We identified 16 cases of open fetal surgery (OS), 48 cases of percutaneous fetal intervention (PI), and 93 NI patients. The survival rate was 56.2% in OS, 45.8% in PI (p = 0.568), and 71.0% in
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Herrmann, Marille E., Karen Thompson, Eva M. Wojcik, Robert Martinez, and Aliya N. Husain. "Congenital Sacrococcygeal Teratomas: Effect of Gestational Age on Size, Morphologic Pattern, Ploidy, p53, and ret Expression." Pediatric and Developmental Pathology 3, no. 3 (2000): 240–48. http://dx.doi.org/10.1007/s100249910031.

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Prognosis of infants born with sacrococcygeal teratomas (SCTs) correlates with gestational age (GA). The survival rate after 30 weeks of gestation is 75%, compared to 7% before 30 weeks of gestation. Studies correlating GA with size, morphologic composition of teratomas, ploidy or expression of cell cycle control proteins such as p53, and ret [a tyrosine kinase receptor of the GDNF (glial cell line–derived neurotrophic factors)] receptor family may provide information explaining differences in survival. Seven SCTs (GA 21 to 41 weeks), ranging in size from 5 to 15 cm, were evaluated for morphol
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Suhandri, Wiwin, and Diki Riandi. "Sacrococcygeal Tumor – A Rare Case Report." Jurnal Ilmu Kedokteran (Journal of Medical Science) 18, no. 1 (2024): 64. http://dx.doi.org/10.26891/jik.v18i1.2024.64-67.

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Sacrococcygeal teratoma (SCT) is a rare congenital tumor primarily affecting infants, with a prevalence of approximately 1 in 35,000 live births. These tumors, often detected either prenatally or shortly after birth, originate from germ cells and typically occur at the base of the coccyx. Despite their benign nature, SCTs can pose significant risks to fetal and maternal health, necessitating careful management and monitoring. A 32-year-old primiparous woman presented to Siak Regional Hospital at 36 weeks of gestation with complaints of uterine contractions and bloody mucus discharge from the b
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Aihole, Jayalaxmi Shripati. "A Vague Gluteal Swelling in a Neonate: Challenges in Its Diagnosis and Management. Short Title-Sacroccoygeal Teratoma." Global Pediatric Health 7 (January 2020): 2333794X2098243. http://dx.doi.org/10.1177/2333794x20982438.

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Sacro coccygeal teratoma (SCT) is the most common extra gonadal neoplasm in the pre sacral area occurring in neonatal period. They mostly occur in the midline with a female preponderance. They are usually attached to coccyx, They are believed to be arising from totipotent cells that originate from primitive knot (Hensen’s node), hence are usually attached to coccyx. Infection in a sacrococcygeal teratoma has been rarely reported. Here is a report of a case of vague gluteal mass in a neonate and challenges in its diagnosis and management.
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Khan, Shams ud Din Elias, Md Mahbubur Rahman, Zinia Parveen, and Meherun Nessa. "Sacrococcygeal Teratoma in Children- Experience in a Tertiary Military Hospital." Journal of Armed Forces Medical College, Bangladesh 13, no. 1 (2017): 17–21. http://dx.doi.org/10.3329/jafmc.v13i1.41009.

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Introduction: Sacrococcygeal teratoma (SCT) is the most common solid tumour found in neonates. Most SCTs are reported in neonates and children, but SCTs are found in adults also. SCTs occur more commonly in females than males. If not detected antenatally, clinical features at birth are prominent in most cases as a palpable or visible mass. Surgery is the principal mode of treatment. The standard treatment for SCT with malignant elements is surgery and chemotherapy.
 Objective: To share the experience with sacrococcygeal teratoma, the most common tumour found in newborn in a tertiary milit
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Soroka, V. P. "A rare observation of resection of giant sacrococcygeal teratoma complicated by massive bleeding in a newborn child." Paediatric Surgery. Ukraine, no. 1(86) (March 28, 2025): 137–40. https://doi.org/10.15574/ps.2025.1(86).137140.

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Aim - is to analyze and describe the experience of surgical treatment of giant sacrococcygeal teratoma (SCT) complicated by massive bleeding in a newborn child. Clinical case. A rare clinical observation of resection of giant sacrococcygeal teratoma complicated by massive bleeding in a newborn child is presented. Conclusions. In the presence of negative prognostic factors associated with the risk of hemodynamic and hemorrhagic complications, it is advisable to consider the possibility of surgical treatment in the early neonatal period to prevent fatal consequences. A 2-stage surgical treatment
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Amoah, M., N. Boateng, and F. A. Abantanga. "Sacrococcygeal Teratoma: A 4-Year Experience at Komfo Anokye Teaching Hospital." Postgraduate Medical Journal of Ghana 1, no. 1 (2022): 15–19. http://dx.doi.org/10.60014/pmjg.v1i1.14.

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Background: Sacrococcygeal teratoma (SCT) is the most common solid neoplasm in neonates with an estimated prevalence of 1 in 40000 live births. The purpose of this study is to review the clinical characteristics and determine the outcome of surgical treatment ofneonates and children with SCT in our environment.Methods: A retrospective review of all patients treated for SCT at the paediatric surgery unit between January 2006 and February 2010 was conducted and the results analysed.Results: In all, 18 children were treated over the study period with a female preponderance of 3.5:1. Eleven patien
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Jouannic, Jean-Marie, Marc Dommergues, Fr�d�ric Auber, Roger Bessis, Claire Nihoul-Fekete, and Yves Dumez. "Successful intrauterine shunting of a sacrococcygeal teratoma (SCT) causing fetal bladder obstruction." Prenatal Diagnosis 21, no. 10 (2001): 824–26. http://dx.doi.org/10.1002/pd.147.

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Vinit, N., A. Benachi, J. Rosenblatt, et al. "Growth velocity of fetal sacrococcygeal teratoma as predictor of perinatal morbidity and mortality: multicenter study." Ultrasound in Obstetrics & Gynecology 64, no. 5 (2024): 651–60. http://dx.doi.org/10.1002/uog.29110.

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ABSTRACTObjectiveTo identify prenatal predictors of poor perinatal outcome in fetuses with isolated sacrococcygeal teratoma (SCT).MethodsThis was a retrospective study of fetuses with isolated (non‐syndromic) SCT managed at one of five pediatric surgery and/or fetal medicine centers between January 2007 and December 2017. The primary outcome was the occurrence of poor perinatal outcome, defined as prenatal death (including termination), or neonatal death or severe compromise (hemorrhagic shock). Data regarding prenatal diagnosis (sonographic features both at referral and at the last ultrasound
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Jona, Juda Z. "Progressive Tumor Necrosis and Lethal Hyperkalemia in a Neonate With Sacrococcygeal Teratoma (SCT)." Journal of Perinatology 19, no. 7 (1999): 538–40. http://dx.doi.org/10.1038/sj.jp.7200197.

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Khedr, Elsayed Mohamed Elsayed, Mahmoud Tarek, Hadeer Mohamed NasrEl-Din, Ayman Hussein Abdelsattar, and Osama Abdelazim. "Laparoscopic-assisted Combined Abdominal and Sacral Approach for Sacrococcygeal Teratoma Altman II/III Excision: Case Series." Journal of Indian Association of Pediatric Surgeons 30, no. 2 (2025): 215–19. https://doi.org/10.4103/jiaps.jiaps_174_24.

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ABSTRACT Context: This study aims to optimize patient outcomes and surgical efficacy by integrating laparoscopic and sacral approaches for the excision of presacral teratomas, focusing on Altman type II–III classifications. Methods: A case series was conducted with seven patients diagnosed with sacrococcygeal teratoma (SCT) Altman type II–III. Short- and intermediate-term surgical outcomes were assessed following a combined laparoscopic and sacral approach. The diagnosis was based on clinical examination, elevated serum alpha-fetoprotein levels, and preoperative pelvic magnetic resonance imagi
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Fadler, Kara, and Debbie Fraser Askin. "Sacrococcygeal Teratoma in the Newborn: A Case Study of Prenatal Management and Clinical Intervention." Neonatal Network 27, no. 3 (2008): 185–91. http://dx.doi.org/10.1891/0730-0832.27.3.185.

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Sacrococcygeal teratomas (SCTs) are the most common germinal cell neoplasms of the fetus and neonate. They originate during embryonic development when the primitive streak fails to differentiate among mesodermal, ectodermal, and endodermal tissues in the embryonic disc. This article discusses the fetal pathophysiology of SCTs and the impact of the condition on the newborn. Fetal SCTs can have life-threatening physiologic effects— such as premature labor, dystocia, and high-output cardiac failure—if not managed appropriately. Clinical manifestations, prenatal diagnosis, therapeutic approaches a
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Rubina, O., J. Kulik, О. Моravska, К. Bеrtsun, and R. Homon. "PROFILE OF MALIGNANT IN CHILDREN OF VINNITSIA REGION, CLINICAL EXPERIENCE." Neonatology, surgery and perinatal medicine 11, no. 2(40) (2021): 5–11. http://dx.doi.org/10.24061/2413-4260.xi.2.40.2021.1.

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Introduction. The structure of cancer incidence inchildren has its own characteristics. The majority of tumorsthat appear in childhood are of embryonic origin. Malignantneoplasms (MN) remain one of the most serious diseases ofchildhood. At present, it is obvious that it is impossible totake measures aimed at reducing morbidity and mortalityfrom MN and to improve the quality of life of cancerpatients without proper accounting and registration of thispatients’ group. The structure of oncopathology in childrenof different age groups of Vinnitsia region is given.The purpose of the study is to prov
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van Heurn, Lieke J., Audrey Coumans, Monique C. Haak, et al. "Prognostic accuracy of factors associated with poor outcome in prenatally diagnosed sacrococcygeal teratoma: A systematic review and meta‐analysis." Prenatal Diagnosis 43, no. 12 (2023): 1495–505. http://dx.doi.org/10.1002/pd.6457.

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AbstractSeveral factors associated with poor outcome in patients with prenatally diagnosed sacrococcygeal teratoma (SCT) have been found. However, the prognostic accuracy of these factors has not been well established. Therefore, we aimed to systematically review the prognostic accuracy of factors associated with poor outcome in these patients. We queried Search Premier, COCHRANE Library, EMCARE, EMBASE, PubMed, ScienceDirect, and Web of Science databases to identify studies regarding patients with prenatally diagnosed SCT. Poor outcome was defined as termination of pregnancy (TOP), intrauteri
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Kamaswari, Ida Ayu Dwi, Adinda Putra Pradhana, and Tjokorda Gde Agung Senapathi. "Manajemen Anestesi pada Pasien Pediatri yang Menjalani Operasi Reseksi Tumor dengan Posisi Pronasi: Sebuah Laporan Kasus." Syntax Literate ; Jurnal Ilmiah Indonesia 9, no. 12 (2024): 7259–65. https://doi.org/10.36418/syntax-literate.v9i12.17001.

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Posisi pronasi dapat menimbulkan tantangan dalam manajemen anestesi, khususnya pada pasien pediatri. Sacrococcygeal teratoma (SCT) adalah tumor pediatrik langka dan menimbulkan tantangan anestesi yang signifikan karena lokasi anatomi dan komplikasi yang terkait. Laporan kasus ini membahas manajemen anestesi pada seorang anak perempuan berusia tiga tahun dengan massa pada regio sacrococcygeal yang semakin membesar sejak lahir, menyebabkan nyeri intermiten tanpa gejala fungsional atau sistemik. Pemeriksaan fisik menunjukkan refleks normal dan anemia normositik normokromik ringan dengan trombosit
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Ryan, G., R. Beecroft, E. Finan, et al. "P27.10: Successful fetal therapy for massive fetal sacrococcygeal teratoma (SCT) using radio frequency ablation (RFA)." Ultrasound in Obstetrics and Gynecology 36, S1 (2010): 275. http://dx.doi.org/10.1002/uog.8686.

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Navarro-Perez, Silvia F., Karen Corona-Fernandez, José L. Rodriguez-Chavez, A. Bañuelos-Franco, and María G. Zavala-Cerna. "Significant Clinical Manifestations in Ballantyne Syndrome, after a Case Report and Literature Review: Recognizing Preeclampsia as a Differential Diagnosis." Case Reports in Obstetrics and Gynecology 2019 (March 5, 2019): 1–7. http://dx.doi.org/10.1155/2019/2013506.

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Ballantyne syndrome (BS) also called mirror syndrome is defined by the presence of a clinical triad that includes fetal hydrops and placental and maternal edema. Here we present a clinical case of a 34-year-old woman with a 29 weeks’ pregnancy, who developed BS and fetal loss probably due to failure in prompt recognition of a rapidly growing sacrococcygeal teratoma (SCT). Due to similarities in clinical presentation with preeclampsia and the importance in early identification of the source for BS, we underwent a literature review in order to identify significant signs and symptoms, as well as
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Sarella Angeliki, Tzela Panagiota, Kampoli Maria, et al. "Second-trimester diagnosis and multidisciplinary management of fetal sacrococcygeal teratoma: A case report with favorable perinatal outcome." World Journal of Advanced Research and Reviews 26, no. 3 (2025): 1171–76. https://doi.org/10.30574/wjarr.2025.26.3.2312.

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Background: Sacrococcygeal teratomas (SCTs) are rare congenital tumors arising from totipotent germ cells, most located at the base of the coccyx. Although typically benign, their variable morphology, vascularity, and growth pattern may pose significant perinatal risks, including high-output cardiac failure, fetal hydrops, and dystocia. Early diagnosis and structured prenatal monitoring are critical for optimizing neonatal outcomes. Case Presentation: We report the case of a 37-year-old primigravida in whom a mixed-type SCT was diagnosed at 22+2 weeks of gestation during routine anomaly scanni
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Respondek-Liberska, M., K. Janiak, and S. Forys. "OC18.07: Fetal echo and cardiovascular profile score (CVS) as a prognostic risk factor in fetal sacrococcygeal teratoma (SCT)." Ultrasound in Obstetrics and Gynecology 26, no. 4 (2005): 339. http://dx.doi.org/10.1002/uog.2105.

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Sliepov, O. K., O. V. Perederii, G. O. Grebinichenko, et al. "A rare observation of simultaneous removal of a giant sacrococcygeal teratoma, with massive presacral and external components, and preoperative endovascular occlusion of the feeding arteries of the tumor, in a newborn." Paediatric Surgery. Ukraine, no. 2(83) (June 28, 2024): 97–106. http://dx.doi.org/10.15574/ps.2024.83.97.

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Aim - to analyze and describe the experience of a one-moment removal of a giant sacrococcygeal teratoma (SCT), with massive presacral and external components (III type), and preoperative endovascular occlusion of the feeding arteries of the tumor, in a newborn, based on a clinical case. Clinical case. A unique clinical case of a giant SCT with massive presacral and external components and preoperative endovascular occlusion of the feeding arteries of the tumor in a newborn is presented. Features of perinatal support, preoperative endovascular occlusion of the feeding arteries of the SCT and su
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Nallasamy, Sudha, Stefanie L. Davidson, Lori J. Howell, et al. "The effects of Fetal Surgery on Retinopathy of Prematurity Development." Ophthalmology and Eye Diseases 1 (January 2009): OED.S2746. http://dx.doi.org/10.4137/oed.s2746.

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Background Fetal surgery is selectively offered for severe or life-threatening fetal malformations. These infants are often born prematurely and are thus at risk for retinopathy of prematurity (ROP). It is not known whether fetal surgery confers an increased risk of developing severe ROP relative to published rates in standard premature populations ≤37 weeks of age grouped by birth weight (<1500 grams or ≥1500 grams). Design This is a retrospective chart review. Methods We reviewed the charts of 137 patients who underwent open fetal/fetoscopic surgery from 1996–2004. Surgical indications in
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Sobieraj, Paulina, and Monika Bekiesińska-Figatowska. "Atypical Pelvic Tumors in Children." Cancers 17, no. 4 (2025): 619. https://doi.org/10.3390/cancers17040619.

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Due to the complex anatomy of the pelvis, various tumors may arise in this region. Some of these tumors are well known and have distinctive features that allow them to be identified by magnetic resonance imaging (MRI). These include sacrococcygeal teratoma (SCT), the most prevalent congenital tumor in children, often diagnosed prenatally and most frequently occurring in this anatomical location, and ovarian teratoma, which in its mature form is the most common ovarian neoplasm in children and adolescents. Additionally, rhabdomyosarcoma (RMS), commonly found in the bladder in both genders and i
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