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1

Lee, Yuet-may May, and 李月媚. "Service disengagement in schizophrenia spectrum disorders." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hub.hku.hk/bib/B50434512.

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Disengagement from mental health services by patients with schizophrenia spectrum disorders is an important issue. Most research in this area has been focused on studying the patients’ demographic and clinical characteristics that may be related to disengagement. However, research on patients’ perspective in regard to their decision of disengagement has been limited. An assessment tool developed based on an in--‐‑depth understanding of patients’ subjective experiences may capture other crucial factors. This may widen our scope of understanding of this phenomenon. Therefore, a mixed research m
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Remy, Irving. "Les fonctions visuelles rétiniennes et corticales dans les troubles du spectre de la schizophrénie et les situations à risque de psychose." Electronic Thesis or Diss., Strasbourg, 2024. http://www.theses.fr/2024STRAJ030.

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Les troubles psychotiques sont caractérisés par d’importantes conséquences fonctionnelles avec des preuves émergentes concernant l’altération des fonctions visuelles de bas niveau. Le lien anatomique et fonctionnel entre la rétine et le cortex visuel a notamment permis d’émettre des hypothèses quant à l’association entre les altérations des deux étages visuels. Nous avons investigué les mesures électrophysiologiques visuelles rétiniennes et corticales dans les troubles du spectre de la schizophrénie et dans les situations à risque de psychose dont l’usage régulier de cannabis et les phases pré
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BARATTIERI, DI SAN PIETRO CHIARA. "Semantic and syntactic modifications in Schizophrenia Spectrum Disorders." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2020. http://hdl.handle.net/10281/277375.

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Nonostante la comprovata presenza di alterazioni a carico del linguaggio nei disturbi dello spettro schizofrenico (DSS - American Psychiatric Association, 2013), la piena caratterizzazione del fenomeno non è ancora stata raggiunta. L’ipotesi della “schizofrenia come prezzo da pagare per il linguaggio" (Crow, 1997) apre nuove prospettive al problema sotto osservazione e suggerisce la necessità di un approccio volto a integrare gli strumenti attualmente utilizzati per la valutazione clinica delle abilità linguistiche nei DSS. L’obiettivo generale del presente lavoro è l'avanzamento nella compren
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Gregory, Benjamin Luke. "Questions of continuum and category in autism spectrum disorders and schizophrenia." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708076.

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Darrell-Berry, Hannah. "Predictors and mediators of anger and aggression in schizophrenia spectrum disorders." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/predictors-and-mediators-of-anger-and-aggression-in-schizophrenia-spectrum-disorders(ea8600bc-2498-4f6b-9ff2-6c0315c7db99).html.

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The aim of this thesis was to explore the relationship between anger and aggression, insecure attachment, paranoia and social cognition in psychosis. It is presented as three separate papers: 1) a systematic review examining the relationship between paranoia and aggression in schizophrenia spectrum disorders, 2) an empirical study investigating predictors and mediators of trait anger across the psychosis continuum: the role of insecure attachment, paranoia and social cognition and 3) a critical reflection of the research process. Paper one provides a systematic review of the relationship betwe
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Burns, Amy Minh Nhat. "Theory of mind, social cognition, and neural functioning in schizophrenia spectrum disorders." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/59475.

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Social cognitive functioning has been shown to be impaired in patients with schizophrenia (SZ), and these impairments are associated with functional outcomes. To better understand these deficits this dissertation investigated the neurocognitive processes associated with several social cognitive tasks. A novel irony comprehension paradigm was developed for use with electroencephalogram (EEG). The N400, a negative event related potential (ERP) that occurs 300-500 ms after the onset of a semantically incongruent word, and the P600, a positive ERP that occurs around 500-800 ms, were used to index
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Beulke, Joshua Thomas. "The Effectiveness of Psychotherapy for Schizophrenia Spectrum Disorders in Community Residential Settings." ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2521.

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The purpose of this research was to analyze the effectiveness of psychotherapy for individuals diagnosed with schizophrenia spectrum disorders who reside in community residential settings. The present body of literature did not address the utility of psychotherapy treatment for this population. A key area of focus for this research was whether psychotherapy has an impact on psychiatric hospitalization rates for the target population. An additional research question was whether significant differences exist in psychiatric hospitalization rates between males and females for the target population
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Faiola, Eliana [Verfasser]. "Psychometric, Cognitive, and Oculomotor Characteristics of Schizotypy and Schizophrenia Spectrum Disorders / Eliana Faiola." Bonn : Universitäts- und Landesbibliothek Bonn, 2020. http://d-nb.info/1224270495/34.

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9

Delfin, Carl. "The neural basis of aberrant salience attribution in unmedicated patients with schizophrenia spectrum disorders." Thesis, Högskolan Kristianstad, Sektionen för lärande och miljö, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-12152.

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Due to abnormal functioning of the brain’s reward and prediction system patients with schizophrenia spectrum disorders are thought to assign salience to non-relevant objects and events and to form context-inappropriate associations. The brain’s ventral striatum is critical in the formation of associations, and aberrant associations are believed to create delusional content during psychosis. The study wanted to examine the neural response, particularly in the ventral striatum, combined with subjective reports as patients learn associations in an aversive Pavlovian conditioning paradigm. The sti
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Rouse, Jennifer Louise. "Evaluating the case for kamin blocking as a cognitive endophenotype of schizophrenia spectrum disorders." Thesis, University of Nottingham, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.537788.

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Kaur, Manreena. "Reconceptualising neurophysiological biomarkers of schizophrenia: an investigation of the MMN/P3a complex in early stage psychiatric disorders." Thesis, The University of Sydney, 2013. http://hdl.handle.net/2123/10104.

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This thesis investigated two established neurophysiological biomarkers of schizophrenia: mismatch negativity (MMN) and P3a; purported indices of the deviance detection and orienting response, respectively. In light of recent interest into a shared diathesis model between schizophrenia- and affective-spectrum disorders, this thesis evaluated the utility of MMN/P3a in informing the underlying neurobiology of early stages of schizophrenia- and affective-spectrum disorders. Despite differences in the composition of schizophrenia- and affective-spectrum subgroups, the first two studies showed that
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12

Torbet, Georgina. "Disorders of agency and self in the schizophrenic spectrum." Doctoral thesis, Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2015. http://dx.doi.org/10.18452/17328.

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Schizophrenie ist eine komplexe Störung, die sich in einer Vielzahl von Symptomen manifestiert. Diese schließen Änderungen in der subjektiven Wahrnehmung von sich als ein Selbst in der Welt ein, die als Selbststörungen bezeichnet werden. Der erste Artikel ist eine theoretische Beurteilung der experimentellen Paradigmen, die zur Messung von Agency verwendet werden. Es setzt sich auch mit dem Verständnis von scheinbar widersprüchlichen empirischen Befunden bezüglich Störungen von Agency in der Schizophrenie auseinander. Der zweite Artikel beschreibt eine Verhaltensstudie, in der 50 Probanden an
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Roisko, R. (Riikka). "Parental Communication Deviance as a risk factor for thought disorders and schizophrenia spectrum disorders in offspring:The Finnish Adoptive Family Study." Doctoral thesis, Oulun yliopisto, 2014. http://urn.fi/urn:isbn:9789526206066.

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Abstract Both genetic and biological and psychosocial environmental risk factors contribute to the aetiology of schizophrenia spectrum disorders. Among the much studied environmental risk indicators are parental Communication Deviance (CD) and the winter or spring birth of a child. Genetic and environmental risk factors do not function in isolation from each other, but gene-environment interactions play a major role in the aetiology of psychotic disorders. The aim of this doctoral thesis is to investigate the role of parental CD as a risk factor (together with other risk indicators) for though
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14

Feiger, Jeremy A. "The Impact of Mild Traumatic Brain Injury, Schizophrenia Spectrum Disorders, and Neurocognitive Deficits on Violent Crime." Thesis, California State University, Long Beach, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10838803.

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<p> Mild traumatic brain injury (mTBI) and schizophrenia spectrum disorders (SSD) are conditions characterized by frontal lobe deficits. Past research has shown increased violent and aggressive behavior in both conditions; however, few studies have examined the mechanisms driving this relationship, particularly in non-athlete or non-veteran populations. The current study examined the neurodegenerative effects of repeated mTBI over time on cognitive flexibility and stability deficits in a homeless population. Additionally, we investigated the mediating effects of these deficits on the impact of
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15

Kostrzewa, Richard M., Karolina Wydra, Malgorzata Filip, et al. "Dopamine D2 Receptor Supersensitivity as a Spectrum of Neurotoxicity and Status in Psychiatric Disorders." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/2770.

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Abnormality of dopamine D2 receptor (D2R) function, often observed as D2R supersensitivity (D2RSS), is a commonality of schizophrenia and related psychiatric disorders in humans. Moreover, virtually all psychotherapeutic agents for schizophrenia target D2R in brain. Permanent D2RSS as a feature of a new animal model of schizophrenia was first reported in 1991, and then behaviorally and biochemically characterized over the next 15–20 years. In this model of schizophrenia characterized by production of D2RSS in ontogeny, there are demonstrated alterations of signaling processes, as well as funct
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16

Edwards, Kimberly. "Patterns of Change in Semantic Clustering in Schizophrenia Spectrum Disorders: What Can it Tell Us about the Nature of Clustering Deficits." Thesis, University of North Texas, 2001. https://digital.library.unt.edu/ark:/67531/metadc2906/.

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Semantic clustering has been used as a measure of learning strategies in a number of clinical populations and has been found to be deficient in individuals with Schizophrenia, but less attention has been paid to the dynamic use of this strategy over the course of fixed-order learning trials. In the current study, we examined this pattern of clustering use over trials in a sample of individuals with Schizophrenia, and explored whether the addition of this dynamic information would help us to better predict specific executive deficits. Results suggested that a decrease in semantic clustering acr
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Sousa, Paulo. "The social predictors, psychological and affective processes of formal thought disorder in patients diagnosed with schizophrenia-spectrum disorders." Thesis, University of Liverpool, 2015. http://livrepository.liverpool.ac.uk/2032944/.

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Despite the relevance of formal thought disorder (TD) in psychosis very little is known about its social and environmental predictors and about the role of both cognitive and affective processes in these experiences. Such knowledge is important because it can inform the development of targeted therapeutic strategies to address TD. In Chapter 2 a narrative review of the field of TD is presented. Of note is the consistency of the evidence supporting the role of internal source monitoring, ‘theory-of-mind’ and negative affect in TD and the limited literature on the environmental factors associate
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18

Kamath, Vidyulata. "THE RELATIVE SENSITIVITY OF AN OLFACTORY IDENTIFICATION DEFICIT IN INDIVIDUALS WITH SCHIZOTYPAL PERSONALITY FEATURES." Master's thesis, University of Central Florida, 2007. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3847.

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Olfactory identification deficits have received recent attention as a potentially useful endophenotype for schizophrenia. Examination of this deficit in individuals with schizotypal personality features (SPF) offers an alternative approach to multiple confounds present when examining individuals with schizophrenia. The aim of the current study was to compare the relative sensitivity of performance on measures of olfaction identification and sustained attention to the presence of SPF. Twenty-six undergraduates were defined as having SPF based on scoring in the top 10% of the Abbreviated Schizot
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19

Wojcik, Joanne D. "Clinical Characteristics of People in Randomized Clinical Trials of First Episode Schizophrenia Spectrum Disorders: Attrition versus Non-Attrition Groups." Thesis, Boston College, 2009. http://hdl.handle.net/2345/1031.

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Thesis advisor: Judith Shindul-Rothschild<br>Clinical Characteristics Of People In Randomized Clinical Trials Of First Episode Schizophrenia Spectrum Disorders: Attrition Versus Non-Attrition Groups Submitted by Joanne D. Wojcik PhD, RN Dissertation Advisor Judith Shindul-Rothschild, PhD, RN Abstract Background: Early identification of psychosis and intensive treatment has been the focus of the treatment of people with a first episode (FE) schizophrenia spectrum disorder (SSD). Attrition rates in studies of people in the first episode are high, which makes it difficult to understand the meanin
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20

Breustedt, Sarah. "Autobiographical memory functioning and response to inpatient treatment for people diagnosed with Schizophrenia Spectrum Disorders : and clinical research portfolio." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8486/.

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Background: Impairments in executive functioning and autobiographical memory (AM) are common in people with schizophrenia spectrum disorders (SSD). There is a need for greater understanding of how neurocognitive factors such as these relate to recovery. This is important because improving treatments requires better understanding of the psychological process involved in recovery from SSD. Aims: We aimed to determine the feasibility of assessing AM and metacognitive functioning in the acute phase of psychosis during inpatient admission. Relationships between neuropsychiatric measures and autobio
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Lotter, C. B. "The qualitative affordances of active and receptive music therapy techniques in major depressive disorder and schizophrenia-spectrum psychotic disorders." Thesis, University of Pretoria, 2017. http://hdl.handle.net/2263/63046.

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Background and objectives: Whilst Active and Receptive Music Therapy techniques have been widely researched and are employed within a range of contexts and with diverse client populations, this study reports on their specific qualitative musical and verbal affordances in major depressive disorder and schizophrenia-spectrum psychotic disorders. The study also describes and compares the respective and joint contributions of the music therapy techniques in giving rise to the affordances as well as reporting on the similarities and differences within and between diagnostic groups. This is the
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22

Zonta, Filippo. "Hippocampal volumes in patients with bipolar-schizophrenic spectrum disorders and their unaffected first-degree relatives." Doctoral thesis, Università degli studi di Padova, 2013. http://hdl.handle.net/11577/3423015.

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BACKGROUND: schizophrenic and bipolar disorders are complex and disabling psychiatric diseases whose classical nosography and classification are still under challenging debate aiming to overcome the traditional “Kraepelinian Dichotomy”. For the past hundred years most clinical work and research in psychiatry has proceeded under the assumption that schizophrenia and bipolar disorderaredistinctentities with separate underlying disease processes and treatments. In more recent years there has been increasing evidence for phenomenological, biological and genetic overlap between the two disorders (P
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Mungly, Shazia. "The Prevalence Of Metabolic Disorders And Their Associated Risk Factors In Forensic Patients With Schizophrenia Spectrum Disorders On Clozapine Compared To Haloperidol At Valkenberg Hospital." Master's thesis, Faculty of Health Sciences, 2019. http://hdl.handle.net/11427/31076.

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Background: Various studies have shown that people with serious mental illness have an increased risk for metabolic syndrome with prevalence ranging from 28.7% to 60%. Given the amount of evidence suggesting a link between clozapine and metabolic syndrome, several guidelines have recommended regular clinical monitoring of metabolic syndrome in patients on clozapine. Aim: To determine the screening, prevalence and associated risk factors of metabolic disorders in forensic patients with schizophrenia spectrum disorders who are on clozapine (study group) compared to patients on haloperidol (contr
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Dapšys, Kastytis. "Study of psychiatric disorders and evaluation of their treatment using method of auditory evoked potential P300." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2011. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20111003_114715-42339.

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Recording and analysis of event-related potentials is safe and harmless method of evaluation of cognition and is suitable to follow the changes of cognitive processes induced by psychoactive drugs or other therapeutic procedures. The main aim of the work was to evaluate the influence of atypical antipsychotics risperidone and quetiapine and such nonpharmacological methods as electroconvulsive therapy and metaglossotherapy on the changes of information processing in the auditory system using event-related potential P300 recording and analysis method. Auditory P300 potential was elicited applyin
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Sheets, Willard A. "The Process People with Schizophrenia or Schizoaffective Disorder Use to Return to or Initialy Secure Eemployment Following Diagnosis." Ohio University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1241734324.

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Dapšys, Kastytis. "Psichikos sutrikimų tyrimas ir jų gydymo įvertinimas klausos sukelto potencialo P300 metodu." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2011. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20111003_114604-77038.

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Kognityvieji sukeltieji potencialai arba su įvykiu susiję potencialai (SĮSP) leidžia įvertinti kai kurias kognityviąsias funkcijas. Jie nuo pat sukūrimo pradžios yra sėkmingai taikomi ir psichikos sutrikimų tyrimuose. SĮSP neinvaziškumas, objektyvumas, saugumas leidžia juos taikyti kognityviųjų funkcijų pokyčių, sukeltų medikamentinio gydymo ar kitos nemedikamentinės terapinės procedūros, įvertinimui. Pagrindinis darbo tikslas buvo įvertinti informacijos apdorojimo klausos sistemoje kitimą atipinių antipsichotikų risperidono ir kvetiapino poveikyje ir nemedikamentinių terapijos metodų - elektr
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Cintra, Mariana Vieira. "Prevalência de experiências psicóticas na gestação e fatores de risco associados em uma amostra comunitária." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5142/tde-17112016-163236/.

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O presente estudo investigou a prevalência e a validade de construto das experiências psicóticas (EPs) na gestação e os fatores de risco associados em uma amostra comunitária do município de São Paulo. Foram investigados fatores de risco sociodemográficos, ambientais, transtornos psiquiátricos no presente e ao longo da vida, violência doméstica, capacidade intelectual e histórico familiar de transtornos psiquiátricos. Foram também avaliados desfechos da gestação e do parto. Trata-se de um estudo prospectivo, com início no 3º trimestre de gestação. As entrevistas de avaliação foram realizadas p
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Serpa, Mauricio Henriques. "Avaliação longitudinal de alterações microestruturais cerebrais estado-dependentes em indivíduos com primeiro episódio psicótico, associadas à atividade da enzima fosfolipase A2." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5142/tde-19062017-075614/.

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INTRODUÇÃO: Os transtornos mentais psicóticos são condições frequentes na população geral e estão associados a grande morbidade e disfuncionalidade. Apesar disso, as bases fisiopatológicas destes transtornos ainda estão em investigação. Estudos neuropatológicos post-mortem e de neuroimagem in vivo sugerem haver comprometimento da microestrutura de substância branca (SB) cerebral nestas condições clínicas, associado a alterações da conectividade cerebral. No entanto, nenhuma investigação prévia de neuroimagem avaliou especificamente se tais anormalidades microestruturais podem ser dependentes d
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Fernandez, Arnaud. "Exploration du profil clinique et génétique des patients atteints de schizophrénie précoce et de leurs apparentés au 1er degré - un protocole d’étude familiale et multicentrique en population française : Protocole GenAuDiss." Electronic Thesis or Diss., Université Côte d'Azur, 2021. http://theses.univ-cotedazur.fr/2021COAZ6010.

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La schizophrénie précoce (SP) est une forme rare, sévère et neurodéveloppementale de schizophrénie débutant avant l’âge de 18 ans. Afin de mieux comprendre les bases génétiques complexes de ce trouble nous avons développé un projet pilote avec pour objectif principal de caractériser sur le plan clinique et génétique les patients atteints de SP. Compte tenu du chevauchement clinique et génétique de la SP avec les autres troubles neurodéveloppementaux, dont le Trouble du Spectre de l’Autisme (TSA) et le Trouble Déficit de l’Attention Hyperactivité (TDAH), nous avons porté une attention particuli
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Hill, Kimberley. "The relationship between internalized stigma, negative symptoms and social functioning in schizophrenia spectrum disorders: the mediating role of self-efficacy." Thesis, 2012. http://hdl.handle.net/1959.13/931667.

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Professional Doctorate - Doctor of Clinical Psychology (DCP)<br>Scope: Negative symptoms represent a fundamental component of schizophrenia. Furthermore, as noted in the DSM-IV (American Psychiatric Association, 2000), poor social functioning has been classified as a diagnostic criterion for the disorder. The relationship between both factors has been highlighted in the literature, with negative symptoms being identified as predictors of social functioning. Consequently, considerable research has been devoted to identifying the factors that contribute to negative symptoms. While impairments in
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PIVA, MERLI MICAELA. "Advances in the psychiatric diagnosis for intellectual and relational developmental disorders." Doctoral thesis, 2016. http://hdl.handle.net/2158/1044973.

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During the last ten years the prevalence of autism and Autism Spectrum Disorder (ASD) have increased greatly. In the 60s the most reported rate was 0.5/1.000, while currently the prevalence of ASD in adults is approximately 1/100. Such rapid and significant increase in prevalence estimates raises a number of questions as to the origins of this increase. A recurring issue is the overlap and boundaries between Intellectual Developmental Disorder (lDD), coexisting ASD and Schizophrenia Spectrum Disorders (SSD). In clinical practice many People with IDD (PwIDD) have both pervasive autistic traits
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Shtalman, Polina. "Změny v prožívání jáství u deprese a poruch schizofrenního okruhu." Master's thesis, 2021. http://www.nusl.cz/ntk/nusl-448997.

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Alterations in self-experience is a relatively omitted topic in czech literature. For that reason, the following diploma thesis deals with this issue, in relation to unipolar depression and schizophrenia spectrum disorders. The thesis is divided into two parts - theoretical and practical part of the research. Each chapter of the theoretical part summarizes the crucial information about schizophrenia and other disorders from schizophrenia spectrum that later appears in the research sample - as well as depression. The chapter describes symptomatology, diagnostics, epidemiology, etiopathogenesis
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Villeneuve, Kathe. "L'assiduité aux interventions psychosociales chez les personnes atteintes de troubles psychotiques." Thèse, 2010. http://hdl.handle.net/1866/4280.

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Résumé en français Objectifs : Ce mémoire propose d’explorer l’assiduité aux interventions psychosociales chez les personnes atteintes de troubles psychotiques en répondant à trois questions : 1- Quels sont les facteurs influençant l’assiduité aux interventions psychosociales pour une clientèle atteinte de troubles psychotiques? 2- Sont-ils comparables aux facteurs influençant l’observance à la médication? 3- Quel est le taux d’abandon des interventions psychosociales et quels sont les facteurs qui font varier ce taux? Méthodes : Cette étude a permis de faire la synthèse des facteurs influença
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