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1

A. Delman, S. Koilraj, and P. Lawrence Rozario Raj. "SD and k-SD Prime Cordial graphs." International Journal of Fuzzy Mathematical Archive 15, no. 02 (2018): 189–95. http://dx.doi.org/10.22457/ijfma.v15n2a9.

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Lourdusamy, A., S. Jenifer Wency, and F. Patrick. "On SD-Harmonious Labeling." Mapana - Journal of Sciences 17, no. 3 (2018): 1–15. http://dx.doi.org/10.12723/mjs.46.1.

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A graph G is said to be SD-harmonious labeling if there exists an injection f: V(G) -> {0,1,2,...,q} such that the induced function f*: E(G) ->{0,2,...,2q-2} defined by f(uv)=S+D (mod 2q) is bijective, where S=f(u)+f(v) and D=|f(u)-f(v)|, for every edge uv in E(G). A graph which admits SD-harmonious labeling is called SD-harmonious graph. In this paper, we investigate SD-harmonious labeling of path related graphs, tree related graphs, star related graphs and disjoint union of graphs.
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Lourdusamy, A., and F. Patrick. "Some results on SD-Prime cordial labeling." Proyecciones (Antofagasta) 36, no. 4 (2025): 601–14. https://doi.org/10.22199/issn.0717-6279-2538.

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Given a bijection ʄ : V(G) → {1,2, …,|V(G)|}, we associate 2 integers S = ʄ(u)+ʄ(v) and D = |ʄ(u)-ʄ(v)| with every edge uv in E(G). The labeling ʄ induces an edge labeling ʄ'' : E(G) → {0,1} such that for any edge uv in E(G), ʄ '(uv)=1 if gcd(S,D)=1, and ʄ ' (uv)=0 otherwise. Let eʄ ' (i) be the number of edges labeled with i ∈ {0,1}. We say ʄ is SD-prime cordial labeling if |eʄ '(0)-e ʄ' (1)| ≤ 1. Moreover G is SD-prime cordial if it admits SD-prime cordial labeling. In this paper, we investigate the SD-prime cordial labeling of some derived graphs.
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Prajapati, U. M., and Anit Vantiya. "SD-Prime cordial labeling of alternate k-polygonal snake of various types." Proyecciones (Antofagasta) 40, no. 3 (2021): 619–34. http://dx.doi.org/10.22199/issn.0717-6279-4015.

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Let f : V (G) → {1, 2,..., |V (G)|} be a bijection, and let us denote S = f(u) + f(v) and D = |f(u) − f(v)| for every edge uv in E(G). Let f' be the induced edge labeling, induced by the vertex labeling f, defined as f' : E(G) → {0, 1} such that for any edge uv in E(G), f' (uv)=1 if gcd(S, D)=1, and f' (uv)=0 otherwise. Let ef' (0) and ef' (1) be the number of edges labeled with 0 and 1 respectively. f is SD-prime cordial labeling if |ef' (0) − ef' (1)| ≤ 1 and G is SD-prime cordial graph if it admits SD-prime cordial labeling. In this paper, we have discussed the SD-prime cordial labeling of
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Lourdusamy, A., and F. Patrick. "Some results on SD-Prime cordial labeling." Proyecciones (Antofagasta) 36, no. 4 (2017): 601–14. http://dx.doi.org/10.4067/s0716-09172017000400601.

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Mason, Graeme F., Jullie W. Pan, Wen-Jan Chu, et al. "Measurement of the Tricarboxylic Acid Cycle Rate in Human Grey and White Matter in Vivo by 1H-[13C] Magnetic Resonance Spectroscopy at 4.1T." Journal of Cerebral Blood Flow & Metabolism 19, no. 11 (1999): 1179–88. http://dx.doi.org/10.1097/00004647-199911000-00002.

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13C isotopic labeling data were obtained by 1H-observed/13C-edited magnetic resonance spectroscopy in the human brain in vivo and analyzed using a mathematical model to determine metabolic rates in human grey matter and white matter. 22,5-cc and 56-cc voxels were examined for grey matter and white matter, respectively. When partial volume effects were ignored, the measured tricarboxylic acid cycle rate was 0.72 ± 0.22 (mean ± SD) and 0.29 ± 0.09 μmol min–1 g–1(mean ± SD) in voxels of ∼70% grey and ∼70% white matter, respectively. After correction for partial volume effects using a model with t
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Kamila, Herc, and Zakrzewska Barbara. "Air Transport of Explosives – Modern Solutions." Safety & Defense 4 (October 5, 2018): 37–42. http://dx.doi.org/10.37105/sd.7.

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The paper is an introduction into the area of hazardous materials transportation. It includes the description of hazardous materials, classification of hazardous materials, and the list of documents necessary for organizing transport of such materials, as well as the advantages and disadvantages of air transport of hazardous materials, and identification and resolution of problems. The aim of the article is to present the up-to-date information on air transport of explosives in the Polish Army, to identify the problems encountered during the transport preparation process, and to discuss the so
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Ayudhityasari, Rizky, and Mukti Widayati. "Pengelolaan Perpustakaan di SD Negeri 2 Bolopleret." Educatif Journal of Education Research 4, no. 1 (2021): 54–58. http://dx.doi.org/10.36654/educatif.v4i1.93.

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Penelitian ini bertujuan untuk mendeskripsikan bagaimana pengelolaan perpustakaan di SD Negeri 2 Bolopleret. Jenis penelitian ini adalah penelitian kualitatif deskriptif. Teknik pengumpulan data yang digunakan anara lain observasi, wawancara, dan dokumentasi. Uji keabsahan data dalam penelitian ini dilakukan dengan cara triangulasi metode. Analisis data dengan tahap reduksi data, penyajian data, dan penarikan kesimpulan. Perencanaan perpustakaan meliputi program kerja perpustakaan jangka panjang dan jangka pendek. Anggaran diperoleh dari APBS dan Komite. Pengorganisasian dengan susunan struktu
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Mason, Graeme F., Douglas L. Rothman, Kevin L. Behar та Robert G. Shulman. "NMR Determination of the TCA Cycle Rate and α-Ketoglutarate/Glutamate Exchange Rate in Rat Brain". Journal of Cerebral Blood Flow & Metabolism 12, № 3 (1992): 434–47. http://dx.doi.org/10.1038/jcbfm.1992.61.

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A mathematical model of cerebral glucose metabolism was developed to analyze the isotopic labeling of carbon atoms C4 and C3 of glutamate following an intravenous infusion of [1-13C]glucose. The model consists of a series of coupled metabolic pools representing glucose, glycolytic intermediates, tricarboxylic acid (TCA) cycle intermediates, glutamate, aspartate, and glutamine. Based on the rate of 13C isotopic labeling of glutamate C4 measured in a previous study, the TCA cycle rate in rat brain was determined to be 1.58 ± 0.41 μmol min−1 g−1 (mean ± SD, n = 5). Analysis of the difference betw
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Tamura, Yasuhisa, Asami Eguchi, Guanghua Jin, Mustafa M. Sami, and Yosky Kataoka. "Cortical Spreading Depression Shifts Cell Fate Determination of Progenitor Cells in the Adult Cortex." Journal of Cerebral Blood Flow & Metabolism 32, no. 10 (2012): 1879–87. http://dx.doi.org/10.1038/jcbfm.2012.98.

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Cortical spreading depression (SD) is propagating neuronal and glial depolarization and is thought to underly the pathophysiology of migraine. We have reported that cortical SD facilitates the proliferative activity of NG2-containing progenitor cells (NG2 cells) that give rise to oligodendrocytes and immature neurons under the physiological conditions in the adult mammalian cortex. Astrocytes have an important role in the maintenance of neuronal functions and alleviate neuronal damage after intense neuronal excitation, including SD and seizures. We here investigated whether SD promotes astrocy
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Handayani, Tri, and Endah Sri Hartatik. "PENDAMPINGAN VERIFIKASI KOLEKSI PERPUSTAKAAN PASCA PELABELAN CALL NUMBER JENIS BUKU BACAAN DI SD NEGERI MANYARAN 01 SEMARANG." Harmoni: Jurnal Pengabdian Kepada Masyarakat 8, no. 1 (2024): 41–52. http://dx.doi.org/10.14710/hm.8.1.41-52.

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ABSTRAKVerifikasi koleksi perpustakaan pasca pelabelan call number merupakan kegiatan verifikasi terhadap koleksi perpustakaan pasca dilakukannya pelabelan call number pada punggung-punggung koleksi. Kegiatan ini dilakukan karena ditemukan sejumlah koleksi yang belum mendapatkan label call number pasca kegiatan pelabelan call number pada kegiatan pengabdian kepada masyarakat semester gasal 2023/2024. Sejumlah besar koleksi tersebut bahkan telah ditempel call number nya pada punggung buku masing-masing. Metode yang digunakan adalah observasi dan diskusi. Kegiatan yang dilakukan meliputi: (1) re
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Deurveilher, S., E. M. Cumyn, T. Peers, B. Rusak, and K. Semba. "Estradiol replacement enhances sleep deprivation-induced c-Fos immunoreactivity in forebrain arousal regions of ovariectomized rats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 295, no. 4 (2008): R1328—R1340. http://dx.doi.org/10.1152/ajpregu.90576.2008.

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To understand how female sex hormones influence homeostatic mechanisms of sleep, we studied the effects of estradiol (E2) replacement on c-Fos immunoreactivity in sleep/wake-regulatory brain areas after sleep deprivation (SD) in ovariectomized rats. Adult rats were ovariectomized and implanted subcutaneously with capsules containing 17β-E2 (10.5 μg; to mimic diestrous E2 levels) or oil. After 2 wk, animals with E2 capsules received a single subcutaneous injection of 17β-E2 (10 μg/kg; to achieve proestrous E2 levels) or oil; control animals with oil capsules received an oil injection. Twenty-fo
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Caggiano, Anthony O., and Richard P. Kraig. "Neuronal Nitric Oxide Synthase Expression is Induced in Neocortical Astrocytes after Spreading Depression." Journal of Cerebral Blood Flow & Metabolism 18, no. 1 (1998): 75–87. http://dx.doi.org/10.1097/00004647-199801000-00008.

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Spreading depression (SD) confers either increased susceptibility to ischemic injury or a delayed protection. Because nitric oxide modulates ischemic injury, we investigated if altered expression of nitric oxide synthase (NOS) by SD could account for the effect of SD on ischemia. Furthermore, the identity of cells expressing NOS after SD is important, since SD results in heterogeneous, cell type–specific changes in intracellular environment, which can control NOS activity. Immunohistochemical, computer-based image analyses and Western blotting show that the number of neuronal NOS (nNOS)–positi
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Yndo, Monica C., and Tina Zawacki. "Factors Influencing Labeling Nonconsensual Sex as Sexual Assault." Journal of Interpersonal Violence 35, no. 7-8 (2017): 1803–27. http://dx.doi.org/10.1177/0886260517699948.

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The current study examined the effects of physical attractiveness and sexual interest cues on men’s sexual perceptions of women and whether increases in sexual perceptions of a woman would lead to decreases in labeling of subsequent nonconsensual sex as sexual assault. Two hundred thirty-three male college students ( Mage = 19.17, SD = 1.22) read a vignette describing a hypothetical social interaction between a man and a woman; within the vignette, the female character’s physical attractiveness (attractive vs. less attractive) and the degree to which the female character behaved interested in
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Youngstrom, T. G., and T. J. Bartness. "Catecholaminergic innervation of white adipose tissue in Siberian hamsters." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 268, no. 3 (1995): R744—R751. http://dx.doi.org/10.1152/ajpregu.1995.268.3.r744.

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When Siberian hamsters are transferred from long summerlike days (LDs) to short winterlike days (SDs) they decrease their body weight, primarily as body fat. These SD-induced decreases in lipid stores are not uniform. Internally located white adipose tissue (WAT) pads are depleted preferentially of lipid, whereas the more externally located subcutaneous WAT pads are relatively spared. These data suggest a possible differential sympathetic neural control over catecholamine-induced lipolysis and that lipolytic rates are greater for internal vs. external WAT pads. Moreover, if these differential
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Essman, Michael, Barry Popkin, Camila Corvalán, Marcela Reyes, and Lindsey Taillie. "Sugar-Sweetened Beverage Intake among Chilean Preschoolers and Adolescents in 2016: A Cross-Sectional Analysis." Nutrients 10, no. 11 (2018): 1767. http://dx.doi.org/10.3390/nu10111767.

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Background: Chile has the highest sugar-sweetened beverage (SSB) sales of any country and a growing burden of childhood obesity. This study examines SSB intake in Chilean children after a 5% SSB tax increase in 2014 but prior to marketing, labeling, and school policies implemented in 2016. Methods: 24-h recalls were collected in 2016 from two cohorts comprised of preschoolers 3–5 years of age (n = 961) and adolescents 12–14 years of age (n = 770) from low–moderate income neighborhoods. Beverages were categorized as regulated or unregulated according to whether they exceeded nutrient thresholds
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Agustina, Lina, Rina Astuti, Aminah Asngad, Suparti Suparti, Erma Musbita Tyastuti, and Siti Kartika Sari. "Workshop on eco-enzyme production as the implementation of zero waste concept at SD Muhammadiyah PK Kottabarat Surakarta." Community Empowerment 9, no. 4 (2024): 655–62. http://dx.doi.org/10.31603/ce.10421.

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68% of household waste consists of organic waste, which significantly contributes to environmental pollution and can cause disruption if not managed properly. Unfortunately, proper management of organic waste is lacking, with a predominant method of disposal being dumping in empty land, waterways, or burning. However, organic waste holds potential for eco-friendly solutions such as eco enzymes. The objective of this community service initiative was to train individuals in producing eco enzymes from organic waste at SD Muhammadiyah PK Kottabarat Surakarta. The activities included educating the
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Wen, S., and T. Liao. "Ephedrine causes liver toxicity in SD rats via oxidative stress and inflammatory responses." Human & Experimental Toxicology 40, no. 1 (2020): 16–24. http://dx.doi.org/10.1177/0960327120943938.

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Ephedrine abuse has spread in many parts of the world and severely threatens human health. The mechanism of ephedrine-induced toxicity still remains unclear. This study was performed to investigate the effects of ephedrine treatment on the liver and explore the underlying mechanisms. Sprague Dawley rats were divided into saline and ephedrine groups. Rats were treated with ephedrine at 20 mg/kg or 40 mg/kg ( n = 10) by oral gavage daily for 7 days. Pathological changes were examined by hematoxylin and eosin staining and terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick end la
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Ertikanto, Chandra. "Perbandingan Kemampuan Inkuiri Mahasiswa Pendidikan Guru Sekolah Dasar dalam Perkuliahan Sains." Jurnal Ilmiah Pendidikan Fisika Al-Biruni 6, no. 1 (2017): 103. http://dx.doi.org/10.24042/jpifalbiruni.v6i1.1582.

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The aim of this research is to describe the inquiry ability (knowledge and skill) and the response from students of Elementary School Teachers Education (PGSD) Lampung University towards Elementary School (SD) Science Education Lecture. The research is done with modeling the inquiry learning model, where PGSD students play as SD learners, and the researcher as SD teacher model. Sampling technique used is Quota Sampling, which means random sampling until fulfilled the number wanted. This research is done on 72 students, and start from March to June 2016. Inquiry ability of variable achieved fro
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Daniel, Gregory B., Russell L. Tucker, Theresa Buckman, and Sandra L. Daniel. "In vitro comparison of equine granulocytes labeled with 99mTc-hexamethylpropyleneamine oxime or 111In-oxine." American Journal of Veterinary Research 53, no. 6 (1992): 871–76. http://dx.doi.org/10.2460/ajvr.1992.53.06.871.

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Summary Isolated equine granulocytes (wbc), radiolabeled with 99mTc-hexamethylpropyleneamine oxime (99mTc-hmpao) or 111In-oxine, were evaluated in vitro for their labeling characteristics, viability, and phagocytic function over a 6-hour postlabeling period. Mean ± sd labeling efficiency for 111In-oxine-wbc was 62.2 ± 15.3%, which was significantly (P < 0.001) higher than that for 99mTc-hmpao-wbc (32.0 ± 17.0%). In vitro elution of radiolabel from cells was significantly (P < 0.02) greater for 99mTc-hmpao-wbc at 0.5, 2, and 4 hours, but was not significantly different from elution of rad
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Radke, Michael, Willi Heine, Klaus D. Wutzke, Peter Leitzmann, and Frank Walther. "Tracer Kinetic Studies on a Methionine‐Supplemented Soy‐Based Infant Formula Using 1‐13C‐ and 15N‐Methionine as Tracers." Journal of Pediatric Gastroenterology and Nutrition 21, no. 2 (1995): 209–14. http://dx.doi.org/10.1002/j.1536-4801.1995.tb11770.x.

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Summary:A tracer‐kinetic study using 1‐13C‐ and 15N‐labeled L‐methionine was conducted in order to measure the retention rate of free methionine added to commercially‐produced soy‐based infant formulas. Twelve male infants, fed on a soy formula, received a single‐pulse labeling by oral administration of L‐1‐13C‐methionine (5 mg/kg) and L‐15N‐methionine (10mg/kg). The abundance of expired 13C‐labeled CO2 was measured up to 7 h after administration at 15‐, 30‐, and 60‐min intervals. Additionally, enrichment of total 15N and 15N in urinary ammonia were determined up to 48 h after administration.
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Lu, Wen-Hsien, Kai-Sheng Hsieh, Pei-Jung Lu та ін. "Different Impacts of α- and β-Blockers in Neurogenic Hypertension Produced by Brainstem Lesions in Rat". Anesthesiology 120, № 5 (2014): 1192–204. http://dx.doi.org/10.1097/aln.0000000000000218.

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Abstract Background: Bilateral lesions of nucleus tractus solitarii in rat result in acute hypertension, pulmonary edema, and death within hours. The hypertension results from excessive catecholamine release. Catecholamine can activate connexin43 to regulate cell death. There is no study investigating the cardiopulmonary impacts of different adrenergic blockers and apoptosis mechanism in rat model. Methods: The authors microinjected 6-hydroxydopamine into nucleus tractus solitarii of the rat (n = 8 per group) and evaluated the cardiopulmonary changes after treatment with different concentratio
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Noquet, Carine, Frédéric Meuriot, Sébastien Caillot, et al. "Short-day photoperiod induces changes in N uptake, N partitioning and accumulation of vegetative storage proteins in two Medicago sativa cultivars." Functional Plant Biology 30, no. 8 (2003): 853. http://dx.doi.org/10.1071/fp03099.

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Our objective was to study the effect of short-day photoperiod for 28, 42 and 56 d on growth, N uptake and N partitioning, particularly vegetative storage protein (VSP) accumulation in taproots of two alfalfa (Medicago�sativa L.) cultivars (Lodi and Europe). For both varieties, the reduction of daylength from 16 h (long day,�LD) to 8 h (short day, SD) for 28 d reduced total plant growth by decreasing shoot growth. Nitrogen uptake and N distribution within the plant was determined by 15N labeling. N uptake decreased with SD treatment duration, and was 2- and 3-fold lower for Europe and Lodi, re
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Ertikanto, Chandra. "Perbandingan Kemampuan Inkuiri Mahasiswa Pendidikan Guru Sekolah Dasar dalam Perkuliahan Sains." Jurnal Ilmiah Pendidikan Fisika Al-Biruni 6, no. 1 (2017): 103. https://doi.org/10.24042/jipfalbiruni.v6i1.1582.

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Penelitian ini bertujuan untuk mendeskripsikan kemampuan (pengetahuan dan keterampilan) inkuiri dan tanggapan mahasiswa Pendidikan Guru Sekolah Dasar (PGSD) Universitas Lampung dalam perkuliahan Pendidikan Sains SD. Pelaksanaan penelitiannya dengan model belajar inkuiri secara pemodelan, dimana mahasiswa PGSD berperan sebagai pebelajar SD, dan peneliti sebagai model pengajar SD. Teknik sampling yang digunakan adalah Quota Sampling, yaitu pengambilan sampel secara acak sampai terpenuhi jumlah yang diinginkan. Penelitian ini dilakukan pada 72 orang mahasiswa, dan dilaksanakan mulai Maret sampai
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Handayani, Tri, and Endah Sri Hartatik. "PENDAMPINGAN PELABELAN CALL NUMBER JENIS BUKU BACAAN KOLEKSI PERPUSTAKAAN DI SD NEGERI MANYARAN 01 SEMARANG." Harmoni: Jurnal Pengabdian Kepada Masyarakat 7, no. 2 (2023): 101–10. http://dx.doi.org/10.14710/hm.7.2.101-110.

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Pelabelan call number merupakan kegiatan pengolahan pustaka, khususnya pada sub kegiatan memberi label buku. Keberadaan label call number memudahkan para Pustakawan menemukan lokasi buku dan menjajarkan buku. Keberadaan label call number bagi para Pemustaka adalah memudahkan mereka menemukan lokasi penyimpanan koleksi buku yang mereka perlukan. Kegiatan pengabdian kepada masyarakat di SD Negeri Manyaran 01 Semarang adalah (1) membuat data koleksi buku menggunakan Microsoft Excel. Setiap halaman memuat data buku dengan huruf depan judul yang sama. Huruf depan judul buku diketik pada tab. (2) me
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Schul, David, Daniel Tallmadge, Derek Burress, Deborah Ewald, Belinda Berger, and David Henry. "Determination of Fat in Olestra-Containing Savory Snack Products by Capillary Gas Chromatography." Journal of AOAC INTERNATIONAL 81, no. 4 (1998): 848–68. http://dx.doi.org/10.1093/jaoac/81.4.848.

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Abstract A quantitative method to determine fat in olestra-containing savory snack products was validated within the AOAC Peer-Verified Methods Program. The method may be used to demonstrate compliance with the guidelines of the U.S. Nutrition Labeling and Education Act for labeling products as "fat free" or "low fat." The method can measure total and saturated fat in savory snacks when present at levels of 0.2-10 g total fat and 0.1-3 g saturated fat per 30 g serving. The method is standardized to measure C6- C24 fatty acids. Extraction of olestra-containing savory snack samples with chlorofo
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Lee, Julian W., Steven Arild Wuyts Andersen, Bradley Hittle, et al. "Variability in Manual Segmentation of Temporal Bone Structures in Cone Beam CT Images." Otology & Neurotology 45, no. 3 (2024): e137-e141. http://dx.doi.org/10.1097/mao.0000000000004119.

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Purpose Manual segmentation of anatomical structures is the accepted “gold standard” for labeling structures in clinical images. However, the variability in manual segmentation of temporal bone structures in CBCT images of the temporal bone has not been systematically evaluated using multiple reviewers. Therefore, we evaluated the intravariability and intervariability of manual segmentation of inner ear structures in CBCT images of the temporal bone. Methods Preoperative CBCTs scans of the inner ear were obtained from 10 patients who had undergone cochlear implant surgery. The cochlea, facial
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Vázquez-Moreno, Almitra, Luis Ledesma Amayab, and Abel Lerma. "A CROSS-SECTIONAL STUDY: IMPACT OF AGE, SEX, AND SOCIAL INFLUENCE ON EMOTIONAL SKILLS OF ADOLESCENTS." Psychological Thought 18, no. 1 (2025): 79–98. https://doi.org/10.37708/psyct.v18i1.984.

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The purpose of the current study was to use a self-reporting questionnaire to appraise the emotional abilities of a sample of adolescents aged 12 to 18 and to identify if there are any disparities between men and women in these abilities. The sample size comprises 1011 adolescents between 12 and 18 years (481 women, M= 14.92 years, SD = 1.72; 530 men, M = 14.93 years, SD = 1.74), divided into seven age groups. There were significant differences in Expressing and Labeling [F(6, 1010) = 5.141, p = .001] and Managing and Regulating dimensions [F(6, 1010) = 4.760, p = .001] across different age gr
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Woodside, Steven M., Ron C. Makowichuk, Jodie Fadum, Albertus W. Wognum, Allen C. Eaves, and Terry E. Thomas. "Fully Automated Magnetic Labeling and Separation of Hematopoietic Cells from Multiple Samples." Blood 106, no. 11 (2005): 1074. http://dx.doi.org/10.1182/blood.v106.11.1074.1074.

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Abstract Laboratory process automation is an important requirement for streamlining and standardizing technical procedures. Despite the extensive use of magnetic cell separation, only the latter steps in these procedures have been automated. Currently magnetic cell labeling is done manually followed by automated magnetic separation (e.g. AutoMACS and Isolex). Additionally, current technology only allows for processing of a single sample at a time. Our objective was to develop a fully automated system to magnetically separate multiple blood and bone marrow samples. The major barrier to automati
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Feldman, William B., Mufaddal Mahesri, Ameet Sarpatwari, et al. "Removing the FDA’s Boxed Hepatotoxicity Warning and Liver Function Testing Requirement for Ambrisentan." JAMA Network Open 7, no. 7 (2024): e2419873. http://dx.doi.org/10.1001/jamanetworkopen.2024.19873.

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ImportanceEndothelin receptor antagonists are first-line therapy for pulmonary arterial hypertension (PAH). The first 2 agents approved in the class, bosentan and ambrisentan, initially carried boxed warnings for hepatotoxicity and required monthly liver function tests (LFTs) as part of a risk evaluation and mitigation strategy (REMS); however, in 2011, as further safety data emerged on ambrisentan, the boxed hepatotoxicity warning and LFT requirements were removed.ObjectiveTo analyze changes in the use of and LFT monitoring for ambrisentan and bosentan after changes to the ambrisentan labelin
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Handayani, Esti, Didit Rendra Setiawan, and Semiati. "Pengelolaan Administrasi Perpustakaan di SDN Kenokorejo 01." Educatif Journal of Education Research 4, no. 2 (2022): 107–10. http://dx.doi.org/10.36654/educatif.v4i2.252.

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Penelitian ini bertujuan untuk mendeskripsikan pengelolaan administrasi perpustakaan di SD Negeri Kenokorejo 01. Jenis penelitian ini adalah penelitian kualitatif deskriptif. Teknik pengumpulan data yang digunakan antara lain observasi, wawancara, dan dokumentasi.
 keabsahan data yang digunakan dengan cara triangulasi metode. Analisis data dengan tahap reduksi data, penyajian data, dan penarikan kesimpulan. Perencanaan perpustakaan meliputi program kerja perpustakaan jangka panjang dan jangka pendek. Pengorganisasian susunan struktur organisasi perpustakaan dibentuk untuk meningkatkan kua
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Sandberg, Monica B., Anne D. M. Riquier, Kaarina Pihakaski-Maunsbach, Alicia A. McDonough, and Arvid B. Maunsbach. "ANG II provokes acute trafficking of distal tubule Na+-Cl− cotransporter to apical membrane." American Journal of Physiology-Renal Physiology 293, no. 3 (2007): F662—F669. http://dx.doi.org/10.1152/ajprenal.00064.2007.

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The distal convoluted tubule (DCT) Na+-Cl− cotransporter (NCC), the target of thiazide diuretics, is responsible for the reabsorption of 5–10% of filtered NaCl. The aim of this study was to test the hypothesis that acute infusion of the angiotensin-converting enzyme (ACE) inhibitor captopril (at 12 μg/min) for 20 min provokes trafficking of NCC from apical plasma membranes (APM) to subapical cytoplasmic vesicles (SCV), which is reversed by acute ANG II infusion (ANG II at 20 ng·kg−1·min−1 along with 12 μg/min captopril) for 20 min in male Sprague-Dawley rats (250–350 g). By immuno-electron mic
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Sato, George, Yasuo Saijo, Bine Uchiyama, et al. "Prognostic Value of Nucleolar Protein p120 in Patients With Resected Lung Adenocarcinoma." Journal of Clinical Oncology 17, no. 9 (1999): 2721. http://dx.doi.org/10.1200/jco.1999.17.9.2721.

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PURPOSE: In this study we investigated the prognostic significance of proliferation-associated nucleolar protein p120 in primary resected lung adenocarcinoma because it reflects tumor growth fractions in vitro. PATIENTS AND METHODS: Expression levels of p120 in tumors were assessed by immunohistochemistry in 74 patients who underwent radical resection. With clinical follow-up data, the prognostic significance of p120 calculated by labeling indices was evaluated using the Cox proportional hazards model. RESULTS: p120 protein was clearly detected in nucleoli of adenocarcinoma cells. Its expressi
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Kentemich, Thomas, Margret Bahnweg, Frank Mayer, and Hermann Bothe. "Localization of the Reversible Hydrogenase in Cyanobacteria." Zeitschrift für Naturforschung C 44, no. 5-6 (1989): 384–91. http://dx.doi.org/10.1515/znc-1989-5-608.

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Abstract The reversible hydrogenase of the cyanobacterium Anacystis nidulans was purified 250-fold by classical methods. Activity staining on gels obtained by native PAGE allowed to identify two bands. A ntibodies were raised against the electrophoretically homogeneous protein. The molecu­lar weight of the hydrogenase was determined by SD S-PAGE follow ed by Western blot analysis with these antibodies. Crude extracts from the unicellular Anacystis and from heterocysts and vegetative cells of Anabaena variabilis showed precipitation bands of 56 and 17 kd. The reversible hydrogenase appeared to
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35

Xiao, Linyu, and Xiaoyi Liao. "Research on the Guidance of Youth Labor Education Based on the “Combination of Education and Production Labor” Program Based on the Deep Learning Model." Computational Intelligence and Neuroscience 2022 (October 11, 2022): 1–9. http://dx.doi.org/10.1155/2022/2576559.

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At present, there is a lack of research on Marx’s idea of “combining education and productive labor” and its guiding significance for youth labor education, and no effective teaching model has been formed. In response to this problem, this study proposes a semi-supervised deep learning model based on u-wordMixup (SD-uwM). When there is a shortage of labeled samples, semi-supervised learning uses a large number of unlabeled samples to solve the problem of labeling bottlenecks. However, since the unlabeled samples and labeled samples come from different fields, there may be quality problems in t
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36

Grummon, Anna H., Laura A. Gibson, Aviva A. Musicus, Alisa J. Stephens-Shields, Sophia V. Hua, and Christina A. Roberto. "Effects of 4 Interpretive Front-of-Package Labeling Systems on Hypothetical Beverage and Snack Selections." JAMA Network Open 6, no. 9 (2023): e2333515. http://dx.doi.org/10.1001/jamanetworkopen.2023.33515.

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ImportancePolicymakers and researchers have proposed a variety of interpretative front-of-package food labeling systems, but it remains unclear which is most effective at encouraging people to choose healthier foods and beverages, including among people with less education.ObjectiveTo test the effects of 4 interpretative front-of-package food labeling systems on the healthfulness of beverage and snack selections, overall and by education level.Design, Setting, and ParticipantsThis randomized clinical trial of a national sample of US adults 18 years and older was conducted online from November
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Maggiano, N., L. M. Larocca, M. Piantelli, O. Acuto, and P. Musiani. "Expression of T cell receptor-alpha and -beta subunits in human thymocytes. An immunocytologic study." Journal of Immunology 139, no. 5 (1987): 1438–45. http://dx.doi.org/10.4049/jimmunol.139.5.1438.

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Abstract The expression of the T cell receptor (Ti)-alpha and -beta subunits in human thymocytes was studied with the use of two rabbit antisera directed at constant regions of human Ti-alpha- and Ti-beta-chains (H36 and H38, respectively). Immunoperoxidase techniques were employed to count by light and electron microscopy the cells, in the various thymocyte subsets, bearing Ti-alpha and Ti-beta subunits. Of the unfractionated thymocytes, 88% +/- 5 SD and 56% +/- 8 SD were labeled by H38 and H36, respectively. More than 90% of cells in cluster of differentiation (CD)-1+ (mainly cortical) and C
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Pleus, Stefan, Nina Jendrike, Annette Baumstark, Jochen Mende, Cornelia Haug, and Guido Freckmann. "Evaluation of Analytical Performance of Three Blood Glucose Monitoring Systems: System Accuracy, Measurement Repeatability, and Intermediate Measurement Precision." Journal of Diabetes Science and Technology 13, no. 1 (2018): 111–17. http://dx.doi.org/10.1177/1932296818804837.

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Introduction: Blood glucose monitoring systems (BGMS) should provide sufficient analytical quality to allow adequate therapy for diabetes patients. Besides system accuracy, measurement precision is an important aspect of a BGMS’ analytical quality. Methods: Based on ISO 15197:2013/EN ISO 15197:2015, system accuracy, measurement repeatability, and intermediate measurement precision were assessed. ISO 15197:2013 system accuracy criteria require that ⩾95% of individual BGMS’ test strip lot results shall fall within ±15 mg/dl or ±15% of corresponding comparison method results (at glucose concentra
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Benson, Gloria S., Claudia Bartels, Feride Stamatis, et al. "The Use and Understanding of Mild Cognitive Impairment in Routine Specialist Care: A Survey Among German Memory Clinics." Geriatrics 10, no. 1 (2025): 21. https://doi.org/10.3390/geriatrics10010021.

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Objectives: Mild cognitive impairment (MCI) is a heterogeneous clinical syndrome and is important for the diagnosis and management of Alzheimer’s disease (AD). With the expansion of biomarker-based diagnostics, the aim of this study is to clarify the current attitudes towards and the use of MCI, and MCI due to AD, in German memory clinics. Methods: An online survey (50 items) was performed in 2022 among specialized clinicians (N = 45) in German memory clinics to assess the use of MCI and biomarkers in current diagnosis and treatment. Attitudinal and frequency items were assessed with a five-po
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Ayuningtyas, Aulia Gita, Mila Maulidiyah, Nita Khairunnisa, and Ichsan Fauzi Rachman. "Disparitas Sosial dan Ekonomi dalam Novel Hari Terakhir di Rumah Bordil Karya Bode Riswandi." PUSTAKA: Jurnal Bahasa dan Pendidikan 4, no. 1 (2023): 75–83. http://dx.doi.org/10.56910/pustaka.v4i1.1052.

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This research was motivated by the findings of socio-economic disparities in the novel Hari Terakhir di Rumah Bordil. This research aims to reveal disparities as a result of analysis using a literary sociology approach. The type of research used is descriptive analysis. The data collection techniques are reading, writing, listening, processing and data techniques. The research subject is the novel 'Last Day in a Brothel' with the research object of social disparities. The results of the research are based on analysis of the data obtained, namely the discovery of social events with negative lab
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Cha, Dongchul, Chongwon Pae, Se A. Lee, et al. "Differential Biases and Variabilities of Deep Learning–Based Artificial Intelligence and Human Experts in Clinical Diagnosis: Retrospective Cohort and Survey Study." JMIR Medical Informatics 9, no. 12 (2021): e33049. http://dx.doi.org/10.2196/33049.

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Background Deep learning (DL)–based artificial intelligence may have different diagnostic characteristics than human experts in medical diagnosis. As a data-driven knowledge system, heterogeneous population incidence in the clinical world is considered to cause more bias to DL than clinicians. Conversely, by experiencing limited numbers of cases, human experts may exhibit large interindividual variability. Thus, understanding how the 2 groups classify given data differently is an essential step for the cooperative usage of DL in clinical application. Objective This study aimed to evaluate and
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42

Berendt, F., T. Froehlich, M. Boelhauve, T. Guengoer, E. Wolf, and G. J. Arnold. "239 OOCYTE MATURATION IN VITRO: PROTEOME ALTERATIONS ANALYZED BY ULTRA-SENSITIVE FLUOROCHROME LABELING AND NANO-ESI-MS-MS." Reproduction, Fertility and Development 20, no. 1 (2008): 199. http://dx.doi.org/10.1071/rdv20n1ab239.

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In mammals, oocytes are arrested in the diplotene stage of the first prophase until the beginning of the estrous cycle. Directly before ovulation, the oocyte completes the first meiotic division and progresses to metaphase II. This process is mimicked by oocyte maturation in vitro, which is critical in assisted reproduction techniques in humans and animals. A sensitive 2-dimensional (2D) difference gel electrophoresis (DIGE) saturation labeling approach including an internal pooled standard was used for quantitative proteome profiling of immature v. in vitro-matured bovine oocytes. A mixture o
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Blajchman, Morris A., Junzhi Li, Myron Kulczycky, et al. "An Animal Model Suitable for Predicting In Vivo Behavior of Platelets in Humans: A Tool for New Product Development." Blood 104, no. 11 (2004): 3628. http://dx.doi.org/10.1182/blood.v104.11.3628.3628.

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Abstract Testing platelet in vivo activity in an animal model remains an attractive approach for the pre-clinical evaluation of platelets that have been treated or manipulated by a new technology or product. Mirasol PRT™ is a novel pathogen reduction technology based on riboflavin photochemistry for the safety of blood component transfusion. In this study, rabbit platelets were tested for viability after exposure to 2, 3 and 5 J/cm2 of UV light in the presence of 50 μM riboflavin in a polypropylene bag (Sangewald). In order to minimize the potential variations caused by different isotope label
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44

Dubowitz, David J., Edward A. W. Dyer, Rebecca J. Theilmann, Richard B. Buxton, and Susan R. Hopkins. "Early brain swelling in acute hypoxia." Journal of Applied Physiology 107, no. 1 (2009): 244–52. http://dx.doi.org/10.1152/japplphysiol.90349.2008.

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Acute mountain sickness (AMS) and high-altitude cerebral edema share common clinical characteristics, suggesting cerebral swelling may be an important factor in the pathophysiology of AMS. Hypoxia and hypocapnia associated with high altitude are known to exert strong effects on the control of the cerebral circulation, yet how these effects interact during acute hypoxia, and whether AMS-susceptible subjects may have a unique response, is still unclear. To test if self-identified AMS-susceptible individuals show altered brain swelling in response to acute hypoxia, we used quantitative arterial s
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45

Ervik, Øyvind, Ingrid Tveten, Erlend Fagertun Hofstad, et al. "Automatic Segmentation of Mediastinal Lymph Nodes and Blood Vessels in Endobronchial Ultrasound (EBUS) Images Using Deep Learning." Journal of Imaging 10, no. 8 (2024): 190. http://dx.doi.org/10.3390/jimaging10080190.

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Endobronchial ultrasound (EBUS) is used in the minimally invasive sampling of thoracic lymph nodes. In lung cancer staging, the accurate assessment of mediastinal structures is essential but challenged by variations in anatomy, image quality, and operator-dependent image interpretation. This study aimed to automatically detect and segment mediastinal lymph nodes and blood vessels employing a novel U-Net architecture-based approach in EBUS images. A total of 1161 EBUS images from 40 patients were annotated. For training and validation, 882 images from 30 patients and 145 images from 5 patients
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Xu, Ming-Shu, Shu-Jing Zhang, Dan Zhao, et al. "Electroacupuncture-Induced Neuroprotection against Cerebral Ischemia in Rats: Role of the Dopamine D2 Receptor." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/137631.

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Background. Cerebral ischemia is known to produce brain damage and related behavioural deficits, including memory deficits and motor disorders. Evidence shows that EA significantly promotes recovery of neurological function and thus improves quality of life.Objective. Evidence exists for the involvement of catecholamines in human neuroplasticity. A better understanding of dopaminergic (DAergic) modulation in this process will be important.Methods. A total of 72 adult male Sprague-Dawley (SD) rats were divided into 6 groups: normal, model, EA, spiperone group, EA + spiperone group, and pergolid
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Hirose, Kayo, Yasuo M. Tsutsumi, Rie Tsutsumi та ін. "Role of the O-linked β-N -acetylglucosamine in the Cardioprotection Induced by Isoflurane". Anesthesiology 115, № 5 (2011): 955–62. http://dx.doi.org/10.1097/aln.0b013e31822fcede.

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Background Cardiac protection by volatile anesthetic-induced preconditioning and ischemic preconditioning have similar signaling pathways. Recently, it was reported that augmentation of protein modified with O-linked β-N-acetylglucosamine (O-GlcNAc) contributes to cardiac protection. This study investigated the role of O-GlcNAc in cardiac protection induced by anesthetic-induced preconditioning. Methods O-GlcNAc-modified proteins were visualized by immunoblotting. Tolerance against ischemia or reperfusion was tested in vivo (n = 8) and in vitro (n = 6). The opening of the mitochondrial permeab
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Herndon, Thomas M., Shih-Shih Chen, Michelle Gatmaitan, et al. "Direct in Vivo Evidence of Increased Chronic Lymphocytic Leukemia Cell Proliferation in Lymph Nodes Compared to Bone Marrow and Peripheral Blood." Blood 120, no. 21 (2012): 184. http://dx.doi.org/10.1182/blood.v120.21.184.184.

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Abstract Abstract 184 Chronic Lymphocytic Leukemia (CLL) is characterized by the accumulation of mature B cells in peripheral blood (PB), bone marrow (BM) and lymph node (LN). Recent studies identified the LN as an important site of tumor cell activation and proliferation (Herishanu et al 2011). Using in vivo labeling of “newly-born” cells with deuterated water (2H2O; heavy water), the proliferation rate of CLL cells was estimated to range between 0.1 to >1% of the clone per day (Messmer et al 2005). Furthermore, a CXCR4dimCD5bright population of CLL cells in the PB contained more deuterium
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Greenbank, Alicia, Galit Agam Ben Artzi, and Gabriel Kashy-Rosenbaum. "People Build an Army Builds People: Attitudes towards Military Service by Young People with Disabilities." SOCIAL ISSUES IN ISRAEL 32, no. 2 (2023): 135–64. http://dx.doi.org/10.26351/siii/32-2/6.

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The main objective of this study was to examine people’s attitudes towards the integration of young people with disabilities in the army. Another objective was to examine the direct and indirect relationship between attitudes towards empathic ability and early acquaintance with a soldier with a disability. The sample included 649 participants, mean age = 27.64 (SD = 11.18). Attitudes were measured using three subscales: (1) the importance and contribution of integration, (2) labeling perception, and (3) the right to equality. Empathic ability was measured with a distinction between the cogniti
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Romero, Cesar A., Glauber Cabral, Robert A. Knight, Guangliang Ding, Edward L. Peterson, and Oscar A. Carretero. "Noninvasive measurement of renal blood flow by magnetic resonance imaging in rats." American Journal of Physiology-Renal Physiology 314, no. 1 (2018): F99—F106. http://dx.doi.org/10.1152/ajprenal.00332.2017.

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Renal blood flow (RBF) provides important information regarding renal physiology and nephropathies. Arterial spin labeling–magnetic resonance imaging (ASL-MRI) is a noninvasive method of measuring blood flow without exogenous contrast media. However, low signal-to-noise ratio and respiratory motion artifacts are challenges for RBF measurements in small animals. Our objective was to evaluate the feasibility and reproducibility of RBF measurements by ASL-MRI using respiratory-gating and navigator correction methods to reduce motion artifacts. ASL-MRI images were obtained from the kidneys of Spra
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