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1

Murphy, Richard A., Henry Sunpath, Carmen Castilla, et al. "Second-Line Antiretroviral Therapy." JAIDS Journal of Acquired Immune Deficiency Syndromes 61, no. 2 (2012): 158–63. http://dx.doi.org/10.1097/qai.0b013e3182615ad1.

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2

Calmy, Alexandra, Fernando Pascual, and Nathan Ford. "First-line and second-line antiretroviral therapy." Lancet 364, no. 9431 (2004): 329. http://dx.doi.org/10.1016/s0140-6736(04)16716-0.

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Kulwichit, Wanla. "First-line and second-line antiretroviral therapy." Lancet 364, no. 9431 (2004): 329–30. http://dx.doi.org/10.1016/s0140-6736(04)16717-2.

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Carr, Andrew. "First-line and second-line antiretroviral therapy." Lancet 364, no. 9431 (2004): 330. http://dx.doi.org/10.1016/s0140-6736(04)16718-4.

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Weiss, Jared M., and Thomas E. Stinchcombe. "Second‐Line Therapy for Advanced NSCLC." Oncologist 18, no. 8 (2013): 947–53. http://dx.doi.org/10.1634/theoncologist.2013-0096.

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Brandt, Kenneth D. "Second-line drug therapy for osteoarthritis." Clinical Medicine 1, no. 2 (2001): 110–12. http://dx.doi.org/10.7861/clinmedicine.1-2-110.

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Martin, Mike G., Ramaswamy Govindan, and Daniel Morgensztern. "Second-line therapy for esophageal cancer." Expert Review of Anticancer Therapy 7, no. 6 (2007): 871–76. http://dx.doi.org/10.1586/14737140.7.6.871.

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8

Hamers, Raph L. "Dolutegravir for second-line antiretroviral therapy." Lancet Infectious Diseases 19, no. 3 (2019): 218–19. http://dx.doi.org/10.1016/s1473-3099(19)30035-0.

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Ahmed, Mili, Douma Rabiâa, Jarrar Emna, et al. "Second-Line Therapy in Multiple Sclerosis." Multiple Sclerosis and Related Disorders 37 (January 2020): 101586. http://dx.doi.org/10.1016/j.msard.2019.11.061.

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Bachner, Mark, and Maria De Santis. "Second-line therapy in bladder cancer." Current Opinion in Urology 19, no. 5 (2009): 533–39. http://dx.doi.org/10.1097/mou.0b013e32832eb473.

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Fleming, Gini F. "Second-Line Therapy for Endometrial Cancer." Obstetrical & Gynecological Survey 71, no. 7 (2016): 406–8. http://dx.doi.org/10.1097/01.ogx.0000484823.85897.c8.

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12

Breccia, Massimo. "Nilotinib: selective inhibitor as second-line therapy." Clinical Management Issues 4, no. 6S (2015): 3–5. http://dx.doi.org/10.7175/cmi.v4i6s.1096.

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13

Simoneaux, Richard. "Second-Line Pembrolizumab Therapy for Urothelial Cancer." Oncology Times 39, no. 10 (2017): 16–18. http://dx.doi.org/10.1097/01.cot.0000520161.64831.c7.

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14

Buosi, R., A. Gatti, S. Carnio, A. Sponghini, C. Olympios, and O. Alabiso. "Second line therapy with cetuximab in NSCLC." Journal of Clinical Oncology 24, no. 18_suppl (2006): 17145. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.17145.

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17145 Background: EGFR is overexpressed in different solid tumors and in 50–80% of NSCLC. The neoplastic growth and metastatic process is correlated with EGFR overexpression, so that it became the target of a new therapeutic approach. The monoclonal antibody (Mab) against the extracellular domain represent the most innovated method of EGFR inaction. Methods: From May to October 2005 10 patients (8 M and 2 F) of median age 62 years with NSCLC in stage IIIB-IV (7 adenocarcinomas and 3 squamocellulars) have been treated with the association of chemotherapy and Cetuximab. All patients presented a
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15

Gisbert, Javier P. "Review: Second-line rescue therapy ofHelicobacter pyloriinfection." Therapeutic Advances in Gastroenterology 2, no. 6 (2009): 331–56. http://dx.doi.org/10.1177/1756283x09347109.

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16

Wood, Alastair J. J., Joseph M. Cash, and John H. Klippel. "Second-Line Drug Therapy for Rheumatoid Arthritis." New England Journal of Medicine 330, no. 19 (1994): 1368–75. http://dx.doi.org/10.1056/nejm199405123301908.

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17

Sasako, Mitsuru. "Ramucirumab: second-line therapy for gastric cancer." Lancet Oncology 15, no. 11 (2014): 1182–84. http://dx.doi.org/10.1016/s1470-2045(14)70464-4.

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18

Price, Timothy J. "Second-line therapy for metastatic colorectal cancer." Lancet Oncology 16, no. 5 (2015): 476–77. http://dx.doi.org/10.1016/s1470-2045(15)70169-5.

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19

Ibañez, Patricio, E. Glasinovic, M. Gatica, Paula Vial, Eduardo Valdivieso, and Roque Saenz. "Inmunomodulation in Ulcerative Colitis. Second Line Therapy?" Gastrointestinal Endoscopy 65, no. 5 (2007): AB259. http://dx.doi.org/10.1016/j.gie.2007.03.606.

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20

Chong, Geoff, and David Cunningham. "Second-line therapy for advanced colorectal cancer." Current Colorectal Cancer Reports 1, no. 1 (2005): 7–12. http://dx.doi.org/10.1007/s11888-005-0010-7.

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21

Ritter, Timothy E., Chris Fourment, Samantha A. Kuten, Thomas C. Hardin, and Lucinda J. Van Anglen. "728 Second-Line Biologic Therapy After Vedolizumab." American Journal of Gastroenterology 114, no. 1 (2019): S429—S430. http://dx.doi.org/10.14309/01.ajg.0000592448.04563.6a.

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22

WILLIAMS, H. JAMES. "COMBINATION SECOND-LINE THERAPY FOR RHEUMATOID ARTHRITIS." Rheumatology 33, no. 7 (1994): 603–4. http://dx.doi.org/10.1093/rheumatology/33.7.603.

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23

Martin, M. G., A. Wang-Gillam, M. A. Waqar, et al. "Second-line systemic therapy for esophageal cancer." Journal of Clinical Oncology 26, no. 15_suppl (2008): 15623. http://dx.doi.org/10.1200/jco.2008.26.15_suppl.15623.

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24

Starling, Naureen, and David Cunningham. "Second-line therapy for advanced colorectal carcinoma." Current Oncology Reports 7, no. 3 (2005): 173–80. http://dx.doi.org/10.1007/s11912-005-0070-5.

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25

Savchenko, I. V., V. V. Breder, I. S. Stilidi, et al. "Second line drug therapy for biliary cancer." Meditsinskiy sovet = Medical Council, no. 22 (December 6, 2022): 136–47. http://dx.doi.org/10.21518/2079-701x-2022-16-22-136-147.

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Biliary cancer is a group of tumors that develop from the epithelium of the intra- and extrahepatic bile ducts (cholangiocarcino-ma), as well as the gallbladder. For 10 years, chemotherapy based on a combination of gemcitabine and cisplatin has remained the standard of first-line therapy in patients with locally advanced or metastatic biliary cancer, resulting in a median overall survival of 11.7 months. With the progression of the disease on the first line, effective options did not previously exist. Attempts to use various chemotherapeutic regimens, both in monotherapy and in combination, ha
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26

Patrikar, Seema, Subramanian Shankar, Atul Kotwal, et al. "Predictors of first line antiretroviral therapy failure and burden of second line antiretroviral therapy." Medical Journal Armed Forces India 73, no. 1 (2017): 5–11. http://dx.doi.org/10.1016/j.mjafi.2016.09.008.

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27

Dzhanyan, I. A., V. V. Breder, O. I. Borisova та K. K. Laktionov. "Рembrolizumab as second line therapy for hepatocellular patient". Meditsinskiy sovet = Medical Council, № 20 (12 грудня 2021): 150–54. http://dx.doi.org/10.21518/2079-701x-2021-20-150-154.

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The optimal hepatocellular cancer (HCC) therapy remains a challenge. Due to checkpoint inhibitors patients with intolerance to the targeted therapy and or those with the impaired liver function can get an appropriate drug therapy. This clinical observation illustrates the long-term effect of pembrolizumab as the 2-line therapy in a patient diagnosed with. Sorafenib in standard doses as first line therapy led to severe toxicity and necessitated the withdrawal of therapy. Although subsequently the doses were reduced and concomitant medications used, sorafenib therapy was discontinued due to pron
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28

Lambert, Michele P. "Immunomodulatory Second-Line Therapies for Immune Thrombocytopenia." Hämostaseologie 39, no. 03 (2019): 266–71. http://dx.doi.org/10.1055/s-0039-1684032.

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AbstractManagement of immune thrombocytopenia (ITP) is complex requiring communication between patients and caregivers to establish a mutual understanding of the impact of the patient's disease on quality of life, the current symptoms and risk of morbidity/mortality and the goals of therapy. The currently available second-line therapies for ITP provide potential for management of thrombocytopenia and bleeding symptoms with medical therapy or surgical intervention potentially offering long-term remission. All therapies are associated with potential side effects and necessary monitoring or modif
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29

Chaudhury, Bobby, and John Grainger. "UK second-line paediatric primary ITP therapy analysis." Archives of Disease in Childhood 106, no. 9 (2021): 929.1–931. http://dx.doi.org/10.1136/archdischild-2020-320646.

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30

Raja, T. "Optimizing second-line therapy for chronic myeloid leukemia." Indian Journal of Cancer 49, no. 1 (2012): 46. http://dx.doi.org/10.4103/0019-509x.98918.

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31

&NA;. "Felbamate stays - but only as second-line therapy." Inpharma Weekly &NA;, no. 960 (1994): 21. http://dx.doi.org/10.2165/00128413-199409600-00044.

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&NA;. "Long-term second line therapy in rheumatoid arthritis." Inpharma Weekly &NA;, no. 971 (1995): 17. http://dx.doi.org/10.2165/00128413-199509710-00042.

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&NA;. "Prescribing second-line therapy for RA in France." Inpharma Weekly &NA;, no. 1327 (2002): 5. http://dx.doi.org/10.2165/00128413-200213270-00010.

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34

&NA;. "Trimetrexate second-line therapy for AIDS-related PCP?" Inpharma Weekly &NA;, no. 1010 (1995): 5. http://dx.doi.org/10.2165/00128413-199510100-00010.

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35

Schmittel, Alexander. "Second-line therapy for small-cell lung cancer." Expert Review of Anticancer Therapy 11, no. 4 (2011): 631–37. http://dx.doi.org/10.1586/era.11.7.

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&NA;. "Methotrexate - second-line therapy for superficial bladder cancer?" Inpharma Weekly &NA;, no. 892 (1993): 14. http://dx.doi.org/10.2165/00128413-199308920-00031.

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&NA;. "Felbamate stays ??? but only as second-line therapy." Reactions Weekly &NA;, no. 524 (1994): 2. http://dx.doi.org/10.2165/00128415-199405240-00002.

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38

Gerullis, Holger, Thomas Otto, and Thorsten H. Ecke. "Targeted agents in second-line bladder cancer therapy." Anti-Cancer Drugs 23, no. 10 (2012): 1003–15. http://dx.doi.org/10.1097/cad.0b013e3283582a33.

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39

Currie, Graeme P., and Sudip Saha. "What About Add-On Second-Line Controller Therapy?" Chest 127, no. 3 (2005): 1077–78. http://dx.doi.org/10.1378/chest.127.3.1077.

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40

Porter, D. R., I. McInnes, J. Hunter, and H. A. Capell. "Outcome of second line therapy in rheumatoid arthritis." Annals of the Rheumatic Diseases 53, no. 12 (1994): 812–15. http://dx.doi.org/10.1136/ard.53.12.812.

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41

Pérez-Valero, Ignacio, and José R. Arribas. "Second-line antiretroviral therapy and the human factor." Lancet HIV 2, no. 2 (2015): e34-e35. http://dx.doi.org/10.1016/s2352-3018(15)00003-x.

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Heath, Vicky. "Second-line therapy for adrenocortical carcinoma proves beneficial." Nature Reviews Endocrinology 6, no. 7 (2010): 355. http://dx.doi.org/10.1038/nrendo.2010.76.

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43

Wachter, Kerri. "Vorinostat fails as second-line therapy for mesothelioma." Community Oncology 8, no. 10 (2011): 459. http://dx.doi.org/10.1016/s1548-5315(12)70150-x.

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44

BATES, BETSY. "Bleomycin as Second Line Therapy Clears Cancerous Lesions." Skin & Allergy News 39, no. 7 (2008): 30. http://dx.doi.org/10.1016/s0037-6337(08)70481-9.

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MECHCATIE, ELIZABETH. "Panel Backs Romidepsin as Second-Line CTCL Therapy." Skin & Allergy News 40, no. 10 (2009): 8. http://dx.doi.org/10.1016/s0037-6337(09)70478-4.

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46

Bex, Axel. "Prognostic accuracy in second-line renal cancer therapy." Lancet Oncology 16, no. 3 (2015): 240–41. http://dx.doi.org/10.1016/s1470-2045(15)70009-4.

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47

Gourd, Elizabeth. "Promising new second-line therapy for Hodgkin lymphoma." Lancet Oncology 20, no. 2 (2019): e76. http://dx.doi.org/10.1016/s1470-2045(19)30016-6.

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48

Timcheva, C. "Second-line targeted therapy of gastrointestinal stromal tumours." memo - Magazine of European Medical Oncology 3, no. 2 (2010): 61–64. http://dx.doi.org/10.1007/s12254-010-0196-5.

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Bird, H. A. "Long-term second-line therapy in rheumatoid arthritis." Clinical Rheumatology 4, no. 2 (1985): 121–23. http://dx.doi.org/10.1007/bf02032281.

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50

Zustovich, Fable, Giuseppe Lombardi, Ornella Nicoletto, and Davide Pastorelli. "Second-line therapy for refractory renal-cell carcinoma." Critical Reviews in Oncology/Hematology 83, no. 1 (2012): 112–22. http://dx.doi.org/10.1016/j.critrevonc.2011.08.008.

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