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1

Shweta. "Sclerosing Stromal Tumor of Ovary: A Rare Case Report." International Journal of Health Sciences and Pharmacy (IJHSP) 1, no. 2 (2017): 11–15. https://doi.org/10.5281/zenodo.836195.

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Sclerosing stromal tumour (SST) is a rare benign ovarian tumor of the sex cord stromal type, occurring predominantly in the second and third decades of life. This tumour is characterized microscopically by having a pseudolobular pattern with cellular areas separated by hypocellular densely hyalinised, edematous stroma interspersed with few prominent blood vessels. Histopathological features which differentiate it from other stromal tumors. We are presenting this case because of its rarity and its simulation with various other ovarian tumours; here we have made an effort to highlight the histom
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2

Aditi, Sanjay Sakarkar, and Shivaji Unde Mukund. "Retrospective Study of Histopathological Spectrum of Ovarian Sex Cord Stromal Tumours at Tertiary Care Hospital – A Three Year Study." International Journal of Pharmaceutical and Clinical Research 14, no. 8 (2022): 605–9. https://doi.org/10.5281/zenodo.13357540.

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<strong>Background:</strong>&nbsp;Sex cord-stromal tumours of the ovary are rare tumours as compared to epithelial tumours of the ovary showing variable histological and biological patterns. Adolescence and young adults are the two age groups in which these tumours are frequently found except for adult granulosa cell tumour which is typically found to develop later i.e. at the age of 50 to 55 years.&nbsp;<strong>Objectives:</strong>&nbsp;This study has been done to find out the frequencies of various subtypes of these tumours and their histopathological spectrum.&nbsp;<strong>Methods:</strong>
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S.M.Tamaskar. "Ovarian Sex Cord-Stromal Tumours: "Newly Recognised Entities"." PJSR 2, no. 1 (2009): 47–55. https://doi.org/10.5281/zenodo.8279321.

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A sex cord-stromal tumour is one that is composed of granulosa cells, theca cells, Sertoli cells, Leydig cells and fibroblasts of stromal origin, singly or in various combinations. A pseudopapillary pattern has been described recently in granulosa cell tumours. This was seen in both juvenile and adult types. Pseudopapillae develop as a secondary or degenerative phenomenon lacking true stromal cores. The distinction of a granulosa cell tumour from a surface epithelial carcinoma can be aided by the use of Epithelial Membrane Antigen (EMA) which is positive in carcinomas and Inhibin and Calretini
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Syeda Iqra Usman, Veena Maheshwari, Sushant Sahui, and Murad Ahmed. "SCLEROSING STROMAL TUMOR: AN INCIDENTAL FINDING IN PATIENT OF INFERTILLITY." International Journal of Histopathological Interpretation 11, no. 2 (2022): 20–24. http://dx.doi.org/10.56501/intjhistopatholinterpret.v11i2.596.

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Ovarian sex cord stromal tumors are infrequent and represents only 7% of all ovarian neoplasm. Cells of origin of these tumors are primitive sex cords or stromal cells. The stromal cells comprise of theca cells, fibroblasts and Leydig cells whereas the gonadal primitive sex cords include granulosa cells and Sertoli cells. According to recent WHO classification sex cord stromal tumors are further subdivided into pure stromal tumors, pure sex cord tumors and mixed sex cord stromal tumors. Here we are going to discuss a rare case of pure stromal tumors i.e., Sclerosing stromal tumor.
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Permi, Harish S., Shetty K. Padma, Supriya Rai, Lakshmi Manjeera, Neetha Poojary, and Teerthanath S. "AN UNUSUAL CYTOLOGICAL EXPERIENCE OF VIRILISING OVARIAN SERTOU-LEYDIG CELL TUMOR - A RARE CASE REPORT." Journal of Health and Allied Sciences NU 03, no. 01 (2013): 63–65. http://dx.doi.org/10.1055/s-0040-1703636.

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AbstractSertoli-Leydig cell tumor of ovary is a gonadal tumour of the sex cord-stromal type. It is a rare tumor comprising 0.1 to 0.5% of all ovarian tumours. Peritoneal cytology has been well established as a diagnostic and staging tool in the management of the common epithelial tumours of ovary. Germ cell, mesenchymal, and sex-cord stromal tumours are much less frequently encountered in peritoneal specimens, often with cytologic features that may pose diagnostic difficulty and dilemma. We report a case of peritoneal fluid cytology of sertoli leydig cell tumor of ovary in a 20 year old female
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Thomas, Alina Ajoy, Meeta Thomas, Rebecca Mathews, and Lillykutty Pothen. "Ovarian sclerosing stromal tumour in a 39-year-old lady- A case report and review of the literature." Indian Journal of Pathology and Oncology 9, no. 2 (2022): 180–83. http://dx.doi.org/10.18231/j.ijpo.2022.042.

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One of the rarest ovarian sex cord-stromal tumour is Sclerosing Stromal Tumour (SST). It commonly presents as lower abdominal pain and tenderness, with or without a mass, and/or abnormal menses. As the clinical presentation and imaging are like borderline or malignant epithelial tumours and sex cord-stromal tumours, accurate preoperative clinical diagnosis can be a challenge and the diagnosis is usually made following postoperative histopathologic examination. Understanding the clinicopathological characteristics of this tumour is vital for accurate preoperative diagnosis, which can be essenti
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7

Mahendran, Revathy, and Madurai Padmanaban Kanchana. "Ovarian fibrothecoma with minor sex cord elements: a case report." International Journal of Research in Medical Sciences 8, no. 4 (2020): 1551. http://dx.doi.org/10.18203/2320-6012.ijrms20201358.

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Ovarian fibroma is the most common sex cord stromal tumour of ovary accounting to 1-5% of all ovarian tumours. Minor sex cord elements in ovarian fibroma are a rare entity occupying less than 10% of tumour area. To the best of our knowledge only 20 cases has been reported till date. This case is presented because of its rarity. Authors reported a case of fibrothecoma with minor sex cord elements in a 70yr old postmenopausal women who presented with postmenopausal bleeding with abdominal mass.
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8

Palmieri, Vincent, Husain Al-Mahmeed, and Peter Metrakos. "Bilateral liver metastases from testicular sex cord-stromal tumour." BMJ Case Reports 12, no. 5 (2019): e228857. http://dx.doi.org/10.1136/bcr-2018-228857.

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A 28-year-old man previously diagnosed and treated for testicular sex cord-stromal tumour (TSCST) presented with symptoms of fever, night sweats and fatigue. Following initial investigations for an infectious aetiology, imaging studies detected two large liver lesions. Histopathological assessment of the tumours revealed that they were metastases from the TSCST for which the patient had radical inguinal orchiectomy and retroperitoneal lymph node dissection 5 years prior. The curative-intent management of the bilobar liver metastases necessitated staged resection due to the chemoresistant and r
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9

Hoogland, Marije, Ivar Bleumer, and Albert Suurmeijer. "Microcystic stromal tumour of testis." BMJ Case Reports 15, no. 3 (2022): e248498. http://dx.doi.org/10.1136/bcr-2021-248498.

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Within the group of gonadal sex cord-stromal tumours, microcystic stromal tumour (MCST) is a rare entity. In the literature, most case series and reviews discussed MCST arising in the ovary, only one case-report concerned a testicular MCST. We present a Caucasian man in his late 30s, who presented with an MCST in his right testis. The tumour was encapsulated and composed of vaguely lobulated cellular nodules and cystic spaces with bland spindle cells and hyalinised fibrous stroma. By immunohistochemistry, the tumour cells expressed cluster designation 10, androgen receptor, steroidogenic facto
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10

Balathil, Ranjana, Ajitha Pulpra, Rabiyabi Vethavayal, and Ani Praveen. "Steroid cell tumour-a rare ovarian tumour: a case report." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 13, no. 10 (2024): 2927–29. http://dx.doi.org/10.18203/2320-1770.ijrcog20242834.

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Steroid cell tumours of the ovary are sex cord stromal tumours which are rare, of all ovarian tumours. Case: Here we present a case of 35-year-old lady who presented to us with complaints of amenorrhoea. With thorough history taking, diagnostic workup and postoperative histopathological evaluation found to have a rare kind of ovarian tumor steroid cell tumor.
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11

Sun, L. "VP04.16: Ovarian sex cord stromal tumour: a case report." Ultrasound in Obstetrics & Gynecology 58, S1 (2021): 108. http://dx.doi.org/10.1002/uog.24076.

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Zanghì, A., G. Catone, G. Marino, G. De Vico, and PA Nicòtina. "Malignant Mixed Sex Cord-stromal Tumour in a Stallion." Reproduction in Domestic Animals 39, no. 5 (2004): 376–79. http://dx.doi.org/10.1111/j.1439-0531.2004.00503.x.

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Keitoku, Miho, Ikuo Konishi, Kanako Nanbu, et al. "Extraovarian Sex Cord-Stromal Tumor." International Journal of Gynecological Pathology 16, no. 2 (1997): 180–85. http://dx.doi.org/10.1097/00004347-199704000-00017.

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14

Sajadi, Kamran P., Rory R. Dalton, and James A. Brown. "Sex Cord-Gonadal Stromal Tumor of the Rete Testis." Advances in Urology 2009 (2009): 1–3. http://dx.doi.org/10.1155/2009/624173.

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A 34-year-old tetraplegic patient with suppurative epididymitis was found on follow-up examination and ultrasonography to have a testicular mass. The radical orchiectomy specimen contained an undifferentiated spindled sex cord-stromal tumor arising in the rete testis. Testicular sex cord-stromal tumors are far less common than germ cell neoplasms and are usually benign. The close relationship between sex cords and ductules of the rete testis during development provides the opportunity for these uncommon tumors to arise anatomically within the rete tesis. This undifferentiated sex cord-stromal
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15

Bajaj, Anubha. "Compilation and Embodiment-Leydig Cell Tumour Testis." Cell & Cellular Life Sciences Journal 9, no. 1 (2024): 1–4. http://dx.doi.org/10.23880/cclsj-16000197.

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Leydig cell tumour is a commonly discerned sex cord stromal tumour arising within testes. Previously designated as interstitial cell tumour, the cellular tumefaction recapitulates non neoplastic Leydig cells. Nearly &lt; 10% neoplasms appear overtly malignant. Neoplasm represents with diffuse or nodular pattern of tumour evolution. Constituent polygonal cells are pervaded with abundant, granular, eosinophilic cytoplasm, uniform spherical nuclei and prominent centric nucleoli. Intracytoplasmic Reinke’s crystals may be discerned.
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16

Schultz, Kris Ann P., Anne K. Harris, Dominik T. Schneider, et al. "Ovarian Sex Cord-Stromal Tumors." Journal of Oncology Practice 12, no. 10 (2016): 940–46. http://dx.doi.org/10.1200/jop.2016.016261.

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Ovarian sex cord-stromal tumors are clinically significant heterogeneous tumors that include several pathologic types. These tumors are often found in adolescents and young adults and can present with hormonal manifestations as well as signs and symptoms of a pelvic mass. Serum tumor markers may assist in preoperative diagnosis and surveillance. Several subtypes are associated with genetic predisposition, including those observed in patients with Peutz-Jegher syndrome. Recent studies have elucidated the relationship between Sertoli-Leydig cell tumors and DICER1 mutations. When classified as In
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17

Vijayraghwan, M. "Sex Cord - Stromal Tumours : Pathological Considerations." Indian Journal of Medical and Paediatric Oncology 25, no. 01 (2004): 32–37. http://dx.doi.org/10.1055/s-0041-1733062.

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18

Brekelbaum, Chad E., Fleurette Abreo, Marjorie Fowler, William S. Kubricht, and James A. Eastham. "Undifferentiated sex cord/stromal testis tumor." Urology 55, no. 3 (2000): 436. http://dx.doi.org/10.1016/s0090-4295(99)00482-3.

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Brekelbaum, Chad E., James A. Eastham, Fleurette Abreo, and William S. Ihbricht. "UNDIFFERENTIATED SEX CORD/STROMAL TESTIS TUMOR." Southern Medical Journal 92, Supplement (1999): S94. http://dx.doi.org/10.1097/00007611-199911001-00235.

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20

CASTELLI, EMANUELE, MARIA SARA SQUEO, NICOLA FARAONE, CRISTIAN FIORI, PAOLA BURLO, and DARIO FONTANA. "UNDIFFERENTIATED SEX CORD-STROMAL TESTIS TUMOR." Journal of Urology 171, no. 6 Part 1 (2004): 2375. http://dx.doi.org/10.1097/01.ju.0000127748.49372.49.

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Rahman, Papiya, Sadia Afroz, Ummey Salma Shabnam, Umama Tun Nesa Emita, Bishnu Pada Dey, and Ferdousy Begum. "Ovarian sclerosing stromal tumour: Report of a new entity with immunohistochemical study." Bangladesh Journal of Medical Science 22, no. 3 (2023): 712–17. http://dx.doi.org/10.3329/bjms.v22i3.65337.

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Sclerosing stromal tumour (SST) is a rare benign sex cord stromal tumour occurring in women in their second and third decades. Patients usually present with menstrual irregularity and pelvic pain. Microscopically, this tumour is characterized by epithelioid and spindle cells arranged in pseudolobules separated by areas with fibrous deposition of various amount. Presence of ‘staghorn like’ proliferating vasculature is the hallmark feature of this tumour. The main differential diagnoses are thecoma and fibroma. Immunohistochemistry can be used to differentiate these tumours. This relatively new
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22

Khanam, Shafeya, Maliha Rashid, Zebunnessa Parvin, et al. "Histological Variants of Ovarian Tumour in Bangladeshi Women." Ibrahim Cardiac Medical Journal 5, no. 1-2 (2017): 40–44. http://dx.doi.org/10.3329/icmj.v5i1-2.53698.

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Objective: Types of ovarian tumour are widely divergent and no age group is immune from ovarian tumour; but certain ages are more vulnerable to develop certain types of tumours. By far, very few studies describing the histological types and subtypes of ovarian tumour in the context of Bangladeshi population have been conducted. The present study was intended to find the histological variants of ovarian tumours in our women.&#x0D; Methods: The present study was carried out in Dhaka Medical College Hospital between July 2001 to June 2002. The total number of patients admitted with a clinical dia
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23

M., Fathima Seles, M. Revathy, and Madurai Padmanabhan Kanchana. "Steroid cell tumour of the ovary: a case report with review of literature." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 8 (2018): 3425. http://dx.doi.org/10.18203/2320-1770.ijrcog20183362.

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Virilising ovarian tumours account for less than 5% of all ovarian tumours. A steroid cell tumour (SCTs) of the ovary comes under the sex cord stromal tumours and accounts for only 0.1% of all ovarian tumours. Almost 75% are functioning tumors with production of androgenic hormones causing virilisation and cushingoid features. They are usually unilateral, benign with only 25-45% malignant cases. Here authors report the incidence of steroid cell tumour in our institution and discuss about a 37-year-old woman with steroid cell tumour, not otherwise specified who presented with oligomenorrhea fol
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24

Narama, I., N. Ano, S. Enaga, K. Nomura, and K. Ozaki. "Ovarian Mixed Germ Cell-sex Cord Stromal Tumour in a Dog." Journal of Comparative Pathology 143, no. 4 (2010): 334. http://dx.doi.org/10.1016/j.jcpa.2010.09.088.

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Laaouini, K., W. Garrouani, M. Bendahou Idrissi, et al. "RARE OVARIAN TUMORS: RADIOLOGICAL-ANATOMICAL DISCORDANCE AND ITS IMPACT ON MANAGEMENT QUALITY - A CASE REPORT." International Journal of Advanced Research 13, no. 02 (2025): 1485–88. https://doi.org/10.21474/ijar01/20519.

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Ovarian tumors are classified into three major histological groups: epithelial tumors, germ cell tumors, and sex cord-stromal tumors. Sex cord-stromal tumors are rare and exhibit a wide spectrum of clinical presentations, often leading to diagnostic challenges. We report the case of a 23-year-old patient with no prior medical history, diagnosed with a sclerosing stromal tumor, a subtype of sex cord-stromal tumors, which exhibited a discordant correlation between radiological and histopathological findings. The complexity of diagnosing primary ovarian tumors based on imaging alone underscores t
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Choi, Yoon-La, Hy-Sook Kim та Geunghwan Ahn. "Immunoexpression of Inhibin α Subunit, Inhibin/Activin βA Subunit and CD99 in Ovarian Tumors". Archives of Pathology & Laboratory Medicine 124, № 4 (2000): 563–69. http://dx.doi.org/10.5858/2000-124-0563-ioisia.

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Abstract Objective.—Anti–inhibin α and inhibin/activin βA subunit and anti-CD99 monoclonal antibodies (mAbs) have recently been demonstrated to be able to label ovarian granulosa cells; thus, they may be of value in the diagnosis of granulosa cell tumors. The present study aimed to determine what combination of these mAbs may be useful for the differential diagnosis of sex cord–stromal tumors of ovary. Design.—Immunohistochemical analyses with anti–inhibin α and inhibin/activin βA subunit antibody and anti-CD99 mAb were performed on 42 ovarian tumors, including sex cord–stromal tumors (29), ov
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Fox, H. "Sex cord-stromal tumours of the ovary." Journal of Pathology 145, no. 2 (1985): 127–48. http://dx.doi.org/10.1002/path.1711450202.

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Mudraje, Sriram, Sahana Shetty, Shyamala Guruvare, and Ranjini Kudva. "Sertoli-Leydig cell ovarian tumour: a rare cause of virilisation and androgenic alopecia." BMJ Case Reports 15, no. 8 (2022): e249324. http://dx.doi.org/10.1136/bcr-2022-249324.

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Sertoli-Leydig cell tumours (SLCTs) represent a rare cause of hyperandrogenic state. SLCTs are sex cord ovarian neoplasms, accounting for &lt;0.2% of all ovarian tumours. Most of the sex cord-stromal tumours have a benign clinical course, with 10%–20% of them at risk of aggressive course. We report a case of a woman in her 30s who presented with androgenic alopecia, virilisation and secondary amenorrhoea. The evaluation revealed an extremely high testosterone level. Imaging for the localisation of source of excess testosterone with contrast-enhanced CT of the abdomen revealed a right ovarian m
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Abdullazade, Samir, Kemal Kosemehmetoglu, Ilknur Adanir, Lale Kutluay, and Alp Usubutun. "Uterine tumors resembling ovarian sex cord-stromal tumors: synchronous uterine tumors resembling ovarian sex cord-stromal tumors and ovarian sex cord tumor." Annals of Diagnostic Pathology 14, no. 6 (2010): 432–37. http://dx.doi.org/10.1016/j.anndiagpath.2010.07.001.

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De Franciscis, Pasquale, Flavio Grauso, Domenico Ambrosio, Marco Torella, Enrico Michelino Messalli, and Nicola Colacurci. "Conservative Resectoscopic Surgery, Successful Delivery, and 60 Months of Follow-Up in a Patient with Endometrial Stromal Tumor with Sex-Cord-Like Differentiation." Case Reports in Obstetrics and Gynecology 2016 (2016): 1–3. http://dx.doi.org/10.1155/2016/5736865.

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Uterine tumors with sex-cord-like differentiation are extremely rare types of uterine stromal neoplasm. These tumors were classified into two groups with considerable practical relevance because clinical behaviour of uterine tumor resembling ovarian sex cord tumor (UTROSCT) differs widely from its closely related endometrial stromal tumors with sex-cord-like elements (ESTSCLE). Treatment and prognosis of these tumors are unresolved issues because of the exiguous number of reported cases. We describe a rare case of endometrial stromal tumor with sex-cord-like differentiation successfully treate
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Ulbright, Thomas M. "Testicular Tumor– Seminoma or Sex Cord-Stromal Tumor." Journal of Urologic Pathology 13, no. 2-3 (2000): 57–60. http://dx.doi.org/10.1385/jup:13:2-3:57.

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Kale, Yash, Girish Kadkol, Madhura Phadke, and Jaydeep Pol. "Adult granulosa cell tumour with yolk sac like areas in a young female." Panacea Journal of Medical Sciences 7, no. 1 (2017): 45–47. https://doi.org/10.18231/2348-7682.2017.0012.

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Granulosa cell tumour (GST) belongs to the sex-cord/stromal tumours of the gonads. We received slides and blocks for review of a 27 years female whounderwent Right oopherectomy. On microscopic examination, architectural pattern was suggestive of either yolk sac tumor andgranulosa cell tumor. Cellular features were suggestive of Granulosa cell tumor because of presence of nuclear grooves. So we decided to go ahead with immunohistochemistry. We used following IHC markers: Inhibin, Calretinin, EMA (Epithelial Membrane antigen), Glypican and PLAP (Placental alkaline phosphatase). Tumor cells were
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Gopal, K., N. Pazhanivel, K. Jeyaraja, V. Kumar, K. Jayakumar, and A. R. Ninu. "Mixed germ cell and sex cord stromal tumour in a cryptorchid dog." Indian Journal of Veterinary Pathology 42, no. 3 (2018): 211. http://dx.doi.org/10.5958/0973-970x.2018.00051.2.

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Reyes, Fatima, Rosa Guerra, Cheng-I. Liao, et al. "Sex cord stromal and germ cell ovarian cancer: Is there a racial disparity?" Journal of Clinical Oncology 38, no. 15_suppl (2020): e18056-e18056. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e18056.

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e18056 Background: We proposed to determine the incidence and presentation of sex cord stromal and germ cell ovarian cancers in various racial groups. Methods: Data was obtained from the United States Cancer Statistics (USCS) and National Cancer Database (NCDB) databases between 2004 and 2016. Chi-squared tests were used for statistical analyses. Results: Of 8,917 women, 48.2% were diagnosed with sex cord stromal ovarian cancer, and 52.5% had germ cell ovarian cancer. White, Black, and Asian individuals comprised 72.5%, 19.8%, and 4.16% of the population, respectively. Of the sex cord stromal
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Joty, Fahmida Sharmin, Farhana Dewan, Fahmida Khan Lima, Bipul Biswas, and Eva Rani Nondi. "Sclerosing Stromal Tumour of Ovary- A Case Report." Bangladesh Journal of Obstetrics & Gynaecology 30, no. 1 (2016): 56–58. http://dx.doi.org/10.3329/bjog.v30i1.30510.

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Sclerosing stromal tumor (SST) is an extremely rare and distinctive sex cord stromal tumor, which occurs predominantly in the second and third decades of life. Approximately 100 cases reported since first described in 1973. It typically present with pelvic/abdominal pain and tenderness, mass, and/or abnormal menses, and with hormonal activity reported predominantly in postmenarchal females. Only 5 cases of these tumors have been reported in premenarchal girls.We report a case of a 18-year-old girl who developed a sclerosing stromal tumor of ovary and presented with excessive menstruation, pelv
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Sameeta, Fnu, Monira Haque, Sadia Haleema, Kelly Roveda, and Wadad Mneimneh. "Uterine Tumors Resembling Sex Cord Stromal Tumors: A Distinctive Entity to Consider in Evaluating the Adenosarcoma." American Journal of Clinical Pathology 152, Supplement_1 (2019): S45—S46. http://dx.doi.org/10.1093/ajcp/aqz113.021.

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Abstract Objectives Uterine tumors resembling ovarian sex cord tumors (UTROSCTs) are rare neoplasms. Approximately 60 cases of UTROSCT are reported in the literature. Methods A 53-year-old female was referred to our institution for definitive surgery following an endometrial biopsy diagnosed as adenosarcoma of the uterus. Her history and physical examination were unremarkable. CT scan showed no evidence of metastatic disease. She underwent a staging hysterectomy with bilateral salpingo-oophorectomy. Grossly, a polypoid mass was seen in the uterine cavity with extension into the myometrium. Res
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Patnaik, A. K., and P. G. Greenlee. "Canine Ovarian Neoplasms: A Clinicopathologic Study of 71 Cases, Including Histology of 12 Granulosa Cell Tumors." Veterinary Pathology 24, no. 6 (1987): 509–14. http://dx.doi.org/10.1177/030098588702400607.

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In a retrospective study of 71 primary ovarian tumors in the dog, epithelial tumors (46%) were more common than sex cord stromal (34%) and germ cell tumors (20%). There were more adenocarcinomas (64%) than adenomas. Sex cord stromal tumors were equally divided into Sertoli-Leydig (12/24) and granulosa cell tumors (12/24). There were equal numbers (7/14) of dysgerminomas and teratomas among the germ cell tumors. Most teratomas (6/7) were malignant. Most granulosa cell tumors were solid; two were mostly cystic. Patterns included sheets of round and ovoid to spindle-shaped cells separated by thin
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Bukhari, Syed Abdullah Javaid, Maira Iqbal Malik, Paul Hutton, Emilio Porfiri, and Mariam Jafri. "Clinical outcome of patients diagnosed with testicular sex cord stromal tumors." Journal of Clinical Oncology 38, no. 15_suppl (2020): e17055-e17055. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e17055.

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e17055 Background: Testicular Sex Cord Stromal Tumors (TSCST) are rare representing approximately 5% of testicular cancers. Leydig Cell Tumours (LCT) constitute 1-3% of testicular tumours, occur commonly in third to sixth decade and are up to 50mm in diameter. Sertoli Cell Tumours(SCT) constitute less than 1%, occur commonly in the fourth decade and have an average diameter of 35mm. High-risk histological features include; tumour size, increased mitotic activity, pleomorphic nuclei, necrosis, vascular invasion and rete testis invasion. Management is surgical with no standard chemotherapy or ra
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Gomes, Tiago Augusto, Elizabeth Aparecida Campos, Adriana Yoshida, Luís Otavio Sarian, Liliana Aparecida Lucci de Angelo Andrade, and Sophie Françoise Derchain. "Preoperative Differentiation of Benign and Malignant Non-epithelial Ovarian Tumors: Clinical Features and Tumor Markers." Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics 42, no. 09 (2020): 555–61. http://dx.doi.org/10.1055/s-0040-1712993.

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Abstract Objective To evaluate the role of clinical features and preoperative measurement of cancer antigen 125 (CA125), human epididymis protein (HE4), and carcinoembryonic antigen (CEA) serum levels in women with benign and malignant non-epithelial ovarian tumors. Methods One hundred and nineteen consecutive women with germ cell, sex cord-stromal, and ovarian leiomyomas were included in this study. The preoperative levels of biomarkers were measured, and then surgery and histopathological analysis were performed. Information about the treatment and disease recurrence were obtained from the m
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Bhargava, Shruti, Jyotsna Vyas, and Adarsh Bhargava. "Ovarian sex cord stromal tumors: an institutional experience." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 9 (2017): 3924. http://dx.doi.org/10.18203/2320-1770.ijrcog20174036.

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Background: Sex cord stromal tumors are a heterogeneous group of rare neoplasms of ovary. These tumors arise from different cells of the ovary and have a fascinating variety of clinical presentations. They are mostly diagnosed on histopathology after surgical removal.Methods: Our study aims at discussing the clinical and histomorphological spectrum of these rare tumors at a tertiary care centre.Results: In our study 158 ovarian sex cord stromal tumors were received over a period of eight years at our institute. Out of these, the most common age group was 30 to 40 years and the chief complaint
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Young, Robert H. "Ovarian sex cord-stromal tumours and their mimics." Pathology 50, no. 1 (2018): 5–15. http://dx.doi.org/10.1016/j.pathol.2017.09.007.

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Lee, R., W. Appel, M. Leahy, and A. J. Birtle. "Multicentre Uk Experience of Sex Cord Stromal Tumours." Annals of Oncology 25 (September 2014): iv300. http://dx.doi.org/10.1093/annonc/mdu337.54.

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Kingston, G. T., and S. Manek. "CD56 immunoreactivity in ovarian sex cord-stromal tumours." Histopathology 51, no. 5 (2007): 723–25. http://dx.doi.org/10.1111/j.1365-2559.2007.02836.x.

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Jashnani, KusumD, ChandrashekarV Hegde, and ShrutikaP Munot. "Alfa-fetoprotein secreting ovarian sex cord-stromal tumor." Indian Journal of Pathology and Microbiology 56, no. 1 (2013): 54. http://dx.doi.org/10.4103/0377-4929.116152.

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Wojda, Katarzyna, and Piotr Sieroszewski. "Endometrial stromal tumor with sex-cord-like elements." Ginekologia Polska 89, no. 5 (2018): 287. http://dx.doi.org/10.5603/gp.a2018.0049.

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Miller, Mark I., Hanina Hibshoosh, and Terry W. Hensle. "An enormous testicular sex cord/gonadal stromal tumor." Journal of Pediatric Surgery 31, no. 7 (1996): 980–82. http://dx.doi.org/10.1016/s0022-3468(96)90428-5.

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Franco, Arie, Norma M. Aquino, Shahid L. Malik, and Carlos Navarro. "Sonographic presentation of uterine sex cord-stromal tumor." Journal of Clinical Ultrasound 27, no. 4 (1999): 199–201. http://dx.doi.org/10.1002/(sici)1097-0096(199905)27:4<199::aid-jcu6>3.0.co;2-r.

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M, Keita,, Traoré, B. Z, Dembélé, K. S, et al. "Ovarian Fibrothecoma: A Case Report." Saudi Journal of Medical and Pharmaceutical Sciences 9, no. 04 (2023): 237–39. http://dx.doi.org/10.36348/sjmps.2023.v09i04.005.

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Introduction: Fibrothecal group tumours are part of the gonadal stromal and sex cord tumours (GSST) and represent 1-4.7% of all organic ovarian tumours and are usually benign. We felt it important to report a case in order to share our experience in the management of fibrothecal tumours of the ovary. Observation: This was a 51-year-old postmenopausal patient who was referred to the hospital for abdominal pain in the context of an abdominal mass. A clinical examination and abdominal ultrasound concluded that the left ovarian tumour was benign. A left annecxectomy was performed and the histologi
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Oruc, Zeynep, Senar Ebinç, and M. Ali Kaplan. "Rare Tumours of the Testis: Twelve Years of Experience." Prague Medical Report 121, no. 3 (2020): 181–93. http://dx.doi.org/10.14712/23362936.2020.17.

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Rare tumours of the testis includes a wide variety of tumours. We aim to present clinical and histological characteristics of our patients with rare tumours of the testis. The medical records of 33 patients who were treated and followed-up for testicular rare tumours in our center between 2007 and 2020 were retrospectively reviewed. Of all the 243 testicular tumours, 222 cases (91.4%) were germ cell tumours and 21 cases (8.6%) were non-germ cell tumours. Thirty-three rare tumours of the testis including rare germ cell tumours and non-germ cell tumours were detected. The mean age of the patient
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Trabelsi, Amel, Soumaya Ben Abdelkarim, Mohamed Hadfi, et al. "Primary Mesenteric Sertoli-Leydig Cell Tumor: A Case Report and Review of the Literature." Journal of Oncology 2008 (2008): 1–3. http://dx.doi.org/10.1155/2008/619637.

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The occurrence of primary sex cord-stromal tumors at extraovarian sites is exceedingly rare. We report a new case of Sertoli-Leydig cell tumor in the mesentery of a 78-year-old woman who presented with occlusive syndrome and reviewed the previously reported cases of extraovarian sex cord-stromal tumors in the English literature.
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