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1

Lee, Merrill, Jerry Yongqiang Chen, Hao Ying, et al. "Quality of life and functional outcome after single-radius and multi-radius total knee arthroplasty." Journal of Orthopaedic Surgery 26, no. 3 (2018): 230949901879241. http://dx.doi.org/10.1177/2309499018792417.

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Purpose: The main objective of this study was to compare quality of life and functional outcome in patients who have undergone a single-radius (SR) or multi-radius (MR) total knee arthroplasty (TKA). The secondary objective was to observe changes in knee range of movement (ROM) and standardized knee scores (KSCs) in these patients. The hypothesis was that there would be no statistically significant difference between the two patient groups in quality of life and functional outcome. Methods: One hundred three SR TKAs were performed by a single surgeon between August 2008 and December 2012. A pr
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INNOCENTI, BERNARDO, HÉCTOR ROBLEDO YAGÜE, RAQUEL ALARIO BERNABÉ, and SILVIA PIANIGIANI. "INVESTIGATION ON THE EFFECTS INDUCED BY TKA FEATURES ON TIBIO-FEMORAL MECHANICS PART I: FEMORAL COMPONENT DESIGNS." Journal of Mechanics in Medicine and Biology 15, no. 02 (2015): 1540034. http://dx.doi.org/10.1142/s0219519415400345.

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The lack of awareness of the exact number of instantaneous centers of knee flexion/extension rotation leads to the presence in the market of total knee arthroplasty (TKA) femoral components designed under different hypotheses. Although single radius (SR) designs are thought to replicate the physiological behavior in a more realistic way, surgeons do not always agree about the veracity of their theoretical advantages with respect to the multiple radii components (J-curve (JC) design). Apart from clinical studies, up to now, any literature study biomechanically and exhaustively compares these tw
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International, Journal of Medical Science and Innovative Research (IJMSIR). "A Comparative Study on Effect of Posterior Femoral Condylar Offset (PCO) on Clinical Results Between Single-Radius (Sr) & Multi-Radius (Mr) Femoral Design Implants/ Components in Posterior Stabilized Total Knee Arthroplasty (PS TKA)." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 5 (2024): 111–21. https://doi.org/10.5281/zenodo.15431315.

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<strong>Conflicts of Interest:</strong> Nil &nbsp; <strong>Abstract</strong> <strong>Introduction</strong>: This study was carried out to compare the effect of femoral Posterior Condylar Offset (PCO) on clinical results between single-radius (SR) and multi-radius (MR) femoral design components in posterior stabilized total knee arthroplasty. (PS TKA) <strong>Material and Methods</strong>: This hospital based prospective observational study was conducted at Department of Orthopaedic, Santokba Durlabhji Memorial Hospital, Jaipur, Rajasthan. Between 1 January 2018 to 31 December 2018 with 6 month
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Ng, Jimmy Wui Guan, Benjamin V. Bloch, and Peter J. James. "Sagittal radius of curvature, trochlea design and ultracongruent insert in total knee arthroplasty." EFORT Open Reviews 4, no. 8 (2019): 519–24. http://dx.doi.org/10.1302/2058-5241.4.180083.

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Multi radius (MR) total knee arthroplasty (TKA) has been associated with mid-flexion instability. Single radius (SR) TKA may provide better anteroposterior stability through single flexion axis and biomechanical advantage for quadriceps function. Medial pivot (MP) TKA and gradually reducing (GR) radius TKA produce better knee kinematics. Clinical outcomes are equivalent for SR, MR and MP TKA. Short-term studies have shown better clinical outcomes and kinematics for GR TKA. Thinner and narrow anterior flange, deeper trochlea groove and more anatomical trochlea design reduces patellofemoral comp
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Mushtaq, Nadeem, David Isaac, Katherine Dillow, Paul Gill, and Alexander Liddle. "Patient-Reported Outcomes following Single- and Multiple-Radius Total Knee Replacement: A Randomized, Controlled Trial." Journal of Knee Surgery 31, no. 01 (2017): 087–91. http://dx.doi.org/10.1055/s-0037-1602132.

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AbstractAlthough single-radius (SR) designs of total knee replacement (TKR) have theoretical benefits, the clinical advantage conferred by such designs is unknown. The aim of this randomized, controlled study was to compare the short-term clinical outcomes of the two design rationales. A total of 105 knees were randomized to receive either a single radius (Scorpio, Stryker; SR Group) or multiple radius (AGC, Zimmer Biomet; MR group) TKR. Patient-reported outcomes (Oxford Knee Score [OKS] and Knee Society Score [KSS]) were collected at 6 weeks, 6 months, and 1 year following surgery. No knees w
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Deehan, David John, K. Milton Ghosh, Alasdair Blain, Lee Longstaff, and Steven Rushton. "Sagittal flexion arc evaluation for a modern generation single-radius femoral component design." Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 232, no. 4 (2018): 412–17. http://dx.doi.org/10.1177/0954411918759136.

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Single-radius femoral total knee design aims to deliver improved kinematic behaviour when compared to the standard two-radii geometry. This study has evaluated the behaviour, through a functional range of motion in the sagittal plane, of a single-radius femoral component compared to a dual-radius standard knee construct. Particular focus was placed on how the flexion axes of the native and replaced knee approximated to the transepicondylar axis through a loaded navigated knee design. Significant differences in flexion arcs were noted between the native and total knee arthroplasty state. These
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Gómez-Barrena, Enrique, Carmelo Fernandez-García, Almudena Fernandez-Bravo, Raquel Cutillas-Ruiz, and Gloria Bermejo-Fernandez. "Functional Performance with a Single-radius Femoral Design Total Knee Arthroplasty." Clinical Orthopaedics and Related Research® 468, no. 5 (2009): 1214–20. http://dx.doi.org/10.1007/s11999-009-1190-2.

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Holthof, Sander, Andrew Amis, Richard Van Arkel, and Mick Rock. "NOVEL ROBOTIC TECHNIQUE TO INVESTIGATE TOTAL KNEE ARTHROPLASTY STABILITY." Orthopaedic Proceedings 105-B, SUPP_13 (2023): 66. http://dx.doi.org/10.1302/1358-992x.2023.13.066.

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AbstractIntroductionMid-flexion instability may cause poor outcomes following TKA. Surgical technique, patient-specific factors, and implant design could all contribute to it, with modelling and fluoroscopy data suggesting the latter may be the root cause. However, current implants all pass the preclinical stability testing standards, making it difficult to understand the effects of implant design on instability. We hypothesized that a more physiological test, analysing functional stability across the range of knee flexion-extension, could delineate the effects of design, independent of surgic
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Sumner, Bonnie, John D. McCamley, David J. Jacofsky, and Marc C. Jacofsky. "Comparison of Knee Kinematics and Kinetics during Stair Ascent in Single-Radius and Multiradius Total Knee Arthroplasty." Journal of Knee Surgery 32, no. 09 (2018): 872–78. http://dx.doi.org/10.1055/s-0038-1669952.

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AbstractTraditionally total knee arthroplasty (TKA) design has been based on theories of the movement of the healthy knee joint. Currently, there are two competing theories on the flexion/extension axis of rotation of the knee with disparate radii of rotation, and thus differing movement patterns. The purpose of our study was to compare stair ascent kinematics and kinetics of single-radius (SR) and multiradius (MR) TKA subjects. We hypothesized that the knee kinematics and kinetics of SR TKA patients would more closely replicate healthy age matched controls during stair ascent than MR TKA pati
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Sumner, Bonnie, John McCamley, David J. Jacofsky, and Marc C. Jacofsky. "Comparison of Knee Kinematics and Kinetics during Stair Descent in Single- and Multi-Radius Total Knee Arthroplasty." Journal of Knee Surgery 33, no. 10 (2019): 1020–28. http://dx.doi.org/10.1055/s-0039-1692652.

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AbstractDespite continuing advances, nearly 20% of patients remain dissatisfied with their total knee arthroplasty (TKA) outcomes. Single-radius (SR) and multiradius (MR) TKA designs are two commonly used knee replacement designs based on competing theories of the flexion/extension axis of the knee. Our aim was to characterize stair descent kinematics and kinetics in SR and MR TKA subjects. We hypothesized that 1 year after TKA, patients who received SR TKA will more closely replicate the knee kinematics and kinetics of healthy age-matched controls during stair descent, than will MR TKA patien
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Liu, Shiluan, Hua Long, Yinglong Zhang, Baoan Ma, and Zhao Li. "Meta-Analysis of Outcomes of a Single-Radius Versus Multi-Radius Femoral Design in Total Knee Arthroplasty." Journal of Arthroplasty 31, no. 3 (2016): 646–54. http://dx.doi.org/10.1016/j.arth.2015.10.017.

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Teeter, Matthew G., Kevin Perry, Xunhua Yuan, James L. Howard, and Brent A. Lanting. "The Effects of Resection Technique on Implant Migration in Single Radius Posterior-Stabilized Total Knee Replacement." Journal of Knee Surgery 33, no. 01 (2018): 078–83. http://dx.doi.org/10.1055/s-0038-1676462.

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AbstractThe purpose of the present study was to measure the effects of gap balancing and resection techniques on migration of a single total knee replacement implant design. A total of 23 patients (24 knees) were recruited on referral to either a surgeon performing gap balancing or a surgeon performing measured resection and followed prospectively. All patients received a fixed bearing, posterior stabilized total knee replacement implant of a single radius femoral component design with cement fixation, and all aspects of care outside of resection technique were identical. Patients underwent ra
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13

Jo, Ah-Reum, Eun-Kyoo Song, Keun-Bae Lee, Hyoung-Yeon Seo, Sung-Kyu Kim, and Jong-Keun Seon. "A Comparison of Stability and Clinical Outcomes in Single-Radius Versus Multi-Radius Femoral Design for Total Knee Arthroplasty." Journal of Arthroplasty 29, no. 12 (2014): 2402–6. http://dx.doi.org/10.1016/j.arth.2014.03.033.

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Zhang, Shurong, Shaohua Liu, Liqin Yang, Shuang Chen, Shiyi Chen, and Jiwu Chen. "Morphological Changes of the Femoral Tunnel and Their Correlation With Hamstring Tendon Autograft Maturation up to 2 Years After Anterior Cruciate Ligament Reconstruction Using Femoral Cortical Suspension." American Journal of Sports Medicine 48, no. 3 (2020): 554–64. http://dx.doi.org/10.1177/0363546519898136.

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Background: Graft healing within the femoral tunnel after anterior cruciate ligament reconstruction (ACLR) using suspensory fixation could be reflected in graft maturation and tunnel morphological changes. However, the correlation between graft maturation and femoral tunnel changes remains unclear. Purpose: To quantitatively evaluate femoral tunnel morphological changes and graft maturation and to analyze their correlation after ACLR using femoral cortical suspension. Study Design: Case series; Level of evidence, 4. Methods: Patients who underwent single-bundle ACLR with a hamstring tendon aut
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Guta, Daniel, Alasdair JA Santini, Matt Gornall, et al. "Short-Term functional comparison of three total knee arthroplasties-Journey II, Genesis II and Profix." Journal of Orthopaedic Surgery 31, no. 1 (2023): 102255362311695. http://dx.doi.org/10.1177/10225536231169572.

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Aim of the study To compare the outcomes of three knee arthroplasty design philosophies and surface tribology. • A zirconium-surfaced, bicruciate-stabilised implant designed to mimic kinematic movement and improve flexion and outcomes; • A cobalt-chrome surfaced, multi-radius design with built-in femoral external rotation to aid balancing and patella tracking through a deeper trochlea groove; • A zirconium-surfaced, single-radius implant designed on surface conformity, particularly within the patello-femoral joint. Methods 313 knee replacements - 103 Journey II, 103 Genesis II and 107 Profix -
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Dinesh, M. A., Vinay Kumar, Raghvendra Kumar, Vibha Rani Gupta, V. Subramanian, and Vijaylakshmi Dayal. "Synthesis and Characterization of the Microwave Dielectric Properties of a (1-x) Li<sub>3</sub>MgNbO<sub>5</sub>–(x) Sr<sub>3</sub>V<sub>2</sub>O<sub>8</sub> Composite for Antenna Application." Key Engineering Materials 1001 (December 18, 2024): 33–42. https://doi.org/10.4028/p-18zfwm.

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This study investigates the fabrication of a cylindrical dielectric resonator antenna (CDRA) using ceramic microwave dielectric composites as a resonator. The composites (1-x) Li3MgNbO5-(x) Sr3V2O8 (x=0.25-0.40) have been synthesized via the conventional solid-state reaction method, incorporating 1% B2O3 to lower the sintering temperature. The 0.70-0.30 composite exhibited optimal microwave dielectric properties with a dielectric constant (εr) of 19.20, a quality factor (Q x f) of 3738 GHz, and a temperature coefficient (τf)of -43 ppm/°C. These characteristics render the 0.70-0.30 composite su
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17

Gordon, Oren, Donald Lee, Brooke Langevin, et al. "125. Dynamic PET facilitated Pharmacokinetic Modeling and High-dose Rifampin Regimens for Staphylococcus aureus Orthopedic Implant Associated Infections: Bench to Bedside." Open Forum Infectious Diseases 8, Supplement_1 (2021): S75—S76. http://dx.doi.org/10.1093/ofid/ofab466.125.

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Abstract Background Rifampin, has potent, dose-dependent sterilizing activity against Gram-positive bacteria with the area under the concentration-time curve (AUC) being the most predictive of bactericidal activity. Combination therapy with rifampin (10-15 mg/kg/day) is recommended to treat S. aureus orthopedic implant associated infections. Recently, high-dose rifampin (35 mg/kg/day) has been shown to be safe in humans and is being evaluated to shorten tuberculosis treatments. Methods Dynamic 11C-rifampin (chemically identical to rifampin) positron emission tomography (PET) was used to determ
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Hodel, Sandro, Julian Hasler, Philipp Fürnstahl, Sandro F. Fucentese, and Lazaros Vlachopoulos. "Elongation Patterns of Posterolateral Corner Reconstruction Techniques: Results Using 3-Dimensional Weightbearing Computed Tomography Simulation." Orthopaedic Journal of Sports Medicine 10, no. 4 (2022): 232596712210902. http://dx.doi.org/10.1177/23259671221090219.

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Background: The isometric characteristics of nonanatomic and anatomic posterolateral corner (PLC) reconstruction techniques under weightbearing conditions remain unclear. Purpose: To (1) simulate graft elongation patterns during knee flexion for 3 different PLC reconstruction techniques (Larson, Arciero, and LaPrade) and (2) compute the most isometric insertion points of the fibular collateral ligament (FCL) graft strands for each technique and report quantitative radiographic landmarks. Study Design: Descriptive laboratory study. Methods: The authors performed a 3-dimensional simulation of 10
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Gheorghe, Ana-Maria, Mihaela Stanciu, Ioana Codruta Lebada, Claudiu Nistor, and Mara Carsote. "An Updated Perspective of the Clinical Features and Parathyroidectomy Impact in Primary Hyperparathyroidism Amid Multiple Endocrine Neoplasia Type 1 (MEN1): Focus on Bone Health." Journal of Clinical Medicine 14, no. 9 (2025): 3113. https://doi.org/10.3390/jcm14093113.

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Background: Multiple endocrine neoplasia type 1 (MEN1)-related primary hyperparathyroidism (MPHPT) belongs to genetic PHPT that accounts for 10% of all PHPT cases, being considered the most frequent hereditary PHPT (less than 5% of all PHPT). Objective: We aimed to provide an updated clinical perspective with a double purpose: to highlight the clinical features in MPHPT, particularly, the bone health assessment, as well as the parathyroidectomy (PTx) impact. Methods: A comprehensive review of the latest 5-year, English-published, PubMed-accessed original studies. Results: The sample-based anal
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Kim, Jahyung, Kyung-Dae Min, Byung-Ill Lee, et al. "Comparison of functional outcomes between single-radius and multi-radius femoral components in primary total knee arthroplasty: a meta-analysis of randomized controlled trials." Knee Surgery & Related Research 32, no. 1 (2020). http://dx.doi.org/10.1186/s43019-020-00067-y.

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Abstract Purpose Our purpose in the current meta-analysis was to compare the functional outcomes in patients who have received single-radius (SR) or multi-radius (MR) femoral components in randomized controlled trials (RCTs) for primary total knee arthroplasty (TKA). The hypothesis was that there would be no statistically significant difference between two groups in terms of functional outcomes. Materials and methods We searched the international electronic databases PubMed, Embase, and the Cochrane Central Register of Controlled Trials up to February 2020 for RCTs that compared functional out
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Mahawar, Deep Kunwar, Vikas Mali, and Tarun Audichya. "EFFECT OF POSTERIOR FEMORAL CONDYLAR OFFSET (PCO) ON CLINICAL RESULTS OF SINGLE-RADIUS (SR) FEMORAL DESIGN IMPLANTS/COMPONENTS IN POSTERIOR STABILIZED TOTAL KNEE ARTHROPLASTY (PS TKA)." INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, March 1, 2024, 60–62. http://dx.doi.org/10.36106/ijsr/6405069.

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Background:Total knee arthroplasty (TKA) is gold standard treatment of choice for Osteoarthritis (OA) knee. When a sufcient posterior femoral condylar offset (PCO) is reconstructed, a larger posterior clearance may be obtained that helps delay impingement on the posterior aspect and maximizes range of exion (ROF). However, the potential correlation between PCO and ROF, especially after posteriorly stabilized (PS) TKA, remains controversial. This study was carried out with the objective to study the effect of PCO on clinical results on single-radius (SR) femoral design components in PS TKA. M
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Arauz, Paul, Yun Peng, Tiffany Castillo, Christian Klemt, and Young-Min Kwon. "In Vitro Kinematic Analysis of Single Axis Radius Posterior-Substituting Total Knee Arthroplasty." Journal of Knee Surgery, April 8, 2020. http://dx.doi.org/10.1055/s-0040-1708039.

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AbstractThis is an experimental study. As current posterior-substituting (PS) total knee arthroplasties have been reported to incompletely restore intrinsic joint biomechanics of the healthy knee, the recently designed single axis radius PS knee system was introduced to increase posterior femoral translation and promote ligament isometry. As there is a paucity of data available regarding its ability to replicate healthy knee biomechanics, this study aimed to assess joint and articular contact kinematics as well as ligament isometry of the contemporary single axis radius PS knee system. Implant
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Luo, Zhenyu, Kai Zhou, Haoyang Wang, Fuxing Pei, and Zongke Zhou. "Comparison between Mid-Term Results of Total Knee Arthroplasty with Single-Radius versus Multiple-Radii Posterior-Stabilized Prostheses." Journal of Knee Surgery, July 13, 2020. http://dx.doi.org/10.1055/s-0040-1713897.

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AbstractSingle-radius (SR) prostheses and multiple-radii (MR) prostheses have different theoretical advantages; however, few comparative studies have been reported. The aim of the study was to compare mid-term clinical, radiological, and survival outcomes of SR and MR posterior-stabilized prostheses in total knee arthroplasty (TKA). Two hundred consecutive patients who underwent TKA between January 2012 and July 2013 were enrolled in the SR group (100 patients) and an MR group (100 patients), with a minimum follow-up of 5 years. Functional, radiological, satisfaction, and survival rates were e
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Holthof, Sander R., Shuntaro Nejima, Mick Rock, et al. "Total knee replacement designs have differing stability under novel robotic testing method in vitro." Knee Surgery, Sports Traumatology, Arthroscopy, July 7, 2025. https://doi.org/10.1002/ksa.12761.

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AbstractPurposeThis study implemented a novel robotic test method to quantify the effect of three distinct total knee arthroplasty (TKA) designs on knee kinematics and stability. It was hypothesised that the implant geometries would affect stability and rollback, with differences between the native and replaced knees, as well as between implant designs.MethodsEight fresh‐frozen cadaveric knees were tested across the arc of flexion‐extension under 710 N compressive load, combined with either no anterior‐posterior (AP) tibial force, 90 N anterior or 90 N posterior drawer force using a robotic ac
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Matsumoto, Tomoyuki, Naoki Nakano, Kazunari Ishida, et al. "The Effect of Prosthesis Type on Intraoperative Soft-Tissue Balance and Clinical Outcomes in Modified Kinematically Aligned Cruciate-Retaining Total Knee Arthroplasty." Journal of Knee Surgery, July 11, 2022. http://dx.doi.org/10.1055/s-0042-1748895.

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Abstract Introduction Kinematically aligned total knee arthroplasty (KA-TKA) has gained interest for achieving more favorable clinical outcomes than mechanically aligned TKA. One of the advantages of KA-TKA is reported to be an easy acquisition of intraoperative soft-tissue balance without excessive medial release for varus osteoarthritis. However, we hypothesized that the prosthesis type affects intraoperative soft-tissue balance even in the KA-TKA. The present study aimed to compare intraoperative soft-tissue balance and clinical outcomes of KA-TKAs using single-radius (SR) or multiradius (M
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Panwar, Govind, Dinesh Khanduja, and Vikas Upadhyay. "Surface quality of AA7079 sheet through single point incremental forming: experimental investigation and parametric optimization." World Journal of Engineering, February 14, 2025. https://doi.org/10.1108/wje-07-2024-0396.

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Purpose The proposed research primarily focuses on optimizing process parameters to enhance the surface quality of AA7079 material components formed incrementally through the single-point incremental forming process. The study experimentally investigates the influence of selected process inputs on the surface quality of the formed material. Experiments were conducted on AA7079 aluminum alloy sheets under varying conditions of specific process factors, including tool diameter, side-wall angle, rotational speed, feed rate and vertical step size. Design/methodology/approach The experimental inves
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Darmanto, D., R. Novriansyah, P. W. Anggoro, R. Ismail, J. Jamari, and A. P. Bayuseno. "A review on flexion angle in high-flexion total knee arthroplasty for indonesian’s need." Frontiers in Mechanical Engineering 8 (November 1, 2022). http://dx.doi.org/10.3389/fmech.2022.1049796.

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Total Knee Arthroplasty (TKA) proposed as an alternative treatment for damaged knee joints of humans is reviewed. The commercial application of TKA can help patients to improve their daily normal activities. Here the high-flex type total knee arthroplasty (High-Flex TKA) is typically designed for the patient’s convenience on which the greater range of motion can be adjusted for extreme activities such as Seiza and Muslim praying. However, the present High-Flex TKAs have not fulfilled the needs of Indonesians for religious activities with a flexion angle of 150°–165°. Therefore, this review aim
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