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Artykuły w czasopismach na temat "Spectrin"

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Machnicka, Beata, Renata Grochowalska, Dżamila M. Bogusławska, and Aleksander F. Sikorski. "The role of spectrin in cell adhesion and cell–cell contact." Experimental Biology and Medicine 244, no. 15 (June 21, 2019): 1303–12. http://dx.doi.org/10.1177/1535370219859003.

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Spectrins are proteins that are responsible for many aspects of cell function and adaptation to changing environments. Primarily the spectrin-based membrane skeleton maintains cell membrane integrity and its mechanical properties, together with the cytoskeletal network a support cell shape. The occurrence of a variety of spectrin isoforms in diverse cellular environments indicates that it is a multifunctional protein involved in numerous physiological pathways. Participation of spectrin in cell–cell and cell–extracellular matrix adhesion and formation of dynamic plasma membrane protrusions and
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Goodman, Steven R., Daniel Johnson, Steven L. Youngentob, and David Kakhniashvili. "The Spectrinome: The Interactome of a Scaffold Protein Creating Nuclear and Cytoplasmic Connectivity and Function." Experimental Biology and Medicine 244, no. 15 (September 4, 2019): 1273–302. http://dx.doi.org/10.1177/1535370219867269.

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We provide a review of Spectrin isoform function in the cytoplasm, the nucleus, the cell surface, and in intracellular signaling. We then discuss the importance of Spectrin’s E2/E3 chimeric ubiquitin conjugating and ligating activity in maintaining cellular homeostasis. Finally we present spectrin isoform subunit specific human diseases. We have created the Spectrinome, from the Human Proteome, Human Reactome and Human Atlas data and demonstrated how it can be a useful tool in visualizing and understanding spectrins myriad of cellular functions. Impact statement Spectrin was for the first 12 y
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Moorthy, Suraj, Lihsia Chen та Vann Bennett. "Caenorhabditis elegans β-G Spectrin Is Dispensable for Establishment of Epithelial Polarity, but Essential for Muscular and Neuronal Function". Journal of Cell Biology 149, № 4 (15 травня 2000): 915–30. http://dx.doi.org/10.1083/jcb.149.4.915.

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The Caenorhabditis elegans genome encodes one α spectrin subunit, a β spectrin subunit (β-G), and a β-H spectrin subunit. Our experiments show that the phenotype resulting from the loss of the C. elegans α spectrin is reproduced by tandem depletion of both β-G and β-H spectrins. We propose that α spectrin combines with the β-G and β-H subunits to form α/β-G and α/β-H heteromers that perform the entire repertoire of spectrin function in the nematode. The expression patterns of nematode β-G spectrin and vertebrate β spectrins exhibit three striking parallels including: (1) β spectrins are associ
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Nicolas, Gaël, Catherine M. Fournier, Colette Galand, Laurence Malbert-Colas, Odile Bournier, Yolande Kroviarski, Monique Bourgeois, et al. "Tyrosine Phosphorylation Regulates Alpha II Spectrin Cleavage by Calpain." Molecular and Cellular Biology 22, no. 10 (May 15, 2002): 3527–36. http://dx.doi.org/10.1128/mcb.22.10.3527-3536.2002.

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ABSTRACT Spectrins, components of the membrane skeleton, are implicated in various cellular functions. Understanding the diversity of these functions requires better characterization of the interacting domains of spectrins, such as the SH3 domain. Yeast two-hybrid screening of a kidney cDNA library revealed that the SH3 domain of αII-spectrin binds specifically isoform A of low-molecular-weight phosphotyrosine phosphatase (LMW-PTP). The αII-spectrin SH3 domain does not interact with LMW-PTP B or C nor does LMW-PTP A interact with the αI-spectrin SH3 domain. The interaction of spectrin with LMW
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Leto, T. L., D. Fortugno-Erikson, D. Barton, T. L. Yang-Feng, U. Francke, A. S. Harris, J. S. Morrow, V. T. Marchesi, and E. J. Benz. "Comparison of nonerythroid alpha-spectrin genes reveals strict homology among diverse species." Molecular and Cellular Biology 8, no. 1 (January 1988): 1–9. http://dx.doi.org/10.1128/mcb.8.1.1-9.1988.

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The spectrins are a family of widely distributed filamentous proteins. In association with actin, spectrins form a supporting and organizing scaffold for cell membranes. Using antibodies specific for human brain alpha-spectrin (alpha-fodrin), we have cloned a rat brain alpha-spectrin cDNA from an expression library. Several closely related human clones were also isolated by hybridization. Comparison of sequences of these and other overlapping nonerythroid and erythroid alpha-spectrin genes demonstrated that the nonerythroid genes are strictly conserved across species, while the mammalian eryth
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Leto, T. L., D. Fortugno-Erikson, D. Barton, T. L. Yang-Feng, U. Francke, A. S. Harris, J. S. Morrow, V. T. Marchesi, and E. J. Benz. "Comparison of nonerythroid alpha-spectrin genes reveals strict homology among diverse species." Molecular and Cellular Biology 8, no. 1 (January 1988): 1–9. http://dx.doi.org/10.1128/mcb.8.1.1.

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The spectrins are a family of widely distributed filamentous proteins. In association with actin, spectrins form a supporting and organizing scaffold for cell membranes. Using antibodies specific for human brain alpha-spectrin (alpha-fodrin), we have cloned a rat brain alpha-spectrin cDNA from an expression library. Several closely related human clones were also isolated by hybridization. Comparison of sequences of these and other overlapping nonerythroid and erythroid alpha-spectrin genes demonstrated that the nonerythroid genes are strictly conserved across species, while the mammalian eryth
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Kennedy, S. P., S. L. Warren, B. G. Forget, and J. S. Morrow. "Ankyrin binds to the 15th repetitive unit of erythroid and nonerythroid beta-spectrin." Journal of Cell Biology 115, no. 1 (October 1, 1991): 267–77. http://dx.doi.org/10.1083/jcb.115.1.267.

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Ankyrin mediates the attachment of spectrin to transmembrane integral proteins in both erythroid and nonerythroid cells by binding to the beta-subunit of spectrin. Previous studies using enzymatic digestion, 2-nitro-5-thiocyanobenzoic acid cleavage, and rotary shadowing techniques have placed the spectrin-ankyrin binding site in the COOH-terminal third of beta-spectrin, but the precise site is not known. We have used a glutathione S-transferase prokaryotic expression system to prepare recombinant erythroid and nonerythroid beta-spectrin from cDNA encoding approximately the carboxy-terminal hal
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Howe, C. L., L. M. Sacramone, M. S. Mooseker, and J. S. Morrow. "Mechanisms of cytoskeletal regulation: modulation of membrane affinity in avian brush border and erythrocyte spectrins." Journal of Cell Biology 101, no. 4 (October 1, 1985): 1379–85. http://dx.doi.org/10.1083/jcb.101.4.1379.

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The spectrins isolated from chicken erythrocytes and chicken intestinal brush border, TW260/240, share a common alpha subunit and a tissue-specific beta subunit. The ability of these related proteins to bind human erythrocyte inside out vesicles (IOVs) and human erythrocyte ankyrin in vitro have been quantitatively compared with human erythrocyte spectrin. Chicken erythrocyte spectrin binds human IOVs and human ankyrin with affinities nearly identical to that for human erythrocyte spectrin. TW260/240 does not significantly bind to either IOVs or ankyrin. These results demonstrate a remarkable
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Baines, Anthony J. "Evolution of spectrin function in cytoskeletal and membrane networks." Biochemical Society Transactions 37, no. 4 (July 22, 2009): 796–803. http://dx.doi.org/10.1042/bst0370796.

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Spectrin is a cytoskeletal protein thought to have descended from an α-actinin-like ancestor. It emerged during evolution of animals to promote integration of cells into tissues by assembling signalling and cell adhesion complexes, by enhancing the mechanical stability of membranes and by promoting assembly of specialized membrane domains. Spectrin functions as an (αβ[H])2 tetramer that cross-links transmembrane proteins, membrane lipids and the actin cytoskeleton, either directly or via adaptor proteins such as ankyrin and 4.1. In the present paper, I review recent findings on the origins and
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Lawler, J., TL Coetzer, VN Mankad, RB Moore, JT Prchal, and J. Palek. "Spectrin-alpha I/61: a new structural variant of alpha-spectrin in a double-heterozygous form of hereditary pyropoikilocytosis." Blood 72, no. 4 (October 1, 1988): 1412–15. http://dx.doi.org/10.1182/blood.v72.4.1412.1412.

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Abstract Recent biochemical studies have led to the identification of abnormal spectrins in the erythrocytes of patients with hereditary pyropoikilocytosis (HPP) and hereditary elliptocytosis (HE). In this report we describe the biochemical characterization of the erythrocytes from a proband with severe HPP who is doubly heterozygous for two mutant spectrins (Sp): Sp alpha I/74 and a new, previously undetected, mutant of alpha-spectrin designated Sp alpha I/61. The proband's erythrocytes are unstable when exposed to 45 degrees C, and her membrane skeletons exhibit instability to shear stress.
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Rozprawy doktorskie na temat "Spectrin"

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McCubbin, T. Paul. "Novel #Beta#-spectrin isoforms." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279964.

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North, Alison Jane. "Spectrin localisation in mammalian striated muscle." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.276872.

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Chen, Tony W. Nam Sang-Chul. "The role of spectrin in Drosophila photoreceptor development." Waco, Tex. : Baylor University, 2008. http://hdl.handle.net/2104/5209.

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Hill, Stephanie. "Folding and association of spectrin tetramer domains : a study of intrinsically disordered proteins from a protein folding perspective." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648579.

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Taupin, Hazel Lindsay. "Tyrosine phosphorylation of spectrin and its relation to neurite growth." Thesis, University of Kent, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497697.

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Bignone, Paola A. "Studies on the phosphorylation and tetramerisation of βII spectrin." Thesis, University of Kent, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.252538.

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Godi, Anna. "Regulation and molecular composition of the Golgi-associated spectrin skeleton." Thesis, Open University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393189.

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Fan, Jun. "The functional studies of a novel Golgi specific spectrin protein /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2003. http://uclibs.org/PID/11984.

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Gough, Lisa Lucio. "Dissecting the functions of the Golgi localized spectrin Syne-1 /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2004. http://uclibs.org/PID/11984.

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O'Toole, Peter John. "Spectrin-lipid interactions : investigations by fluorescence spectroscopy and digital fluorescence microscopy." Thesis, University of Essex, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242333.

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Książki na temat "Spectrin"

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Hartwig, John H. Actin-binding proteins 1: spectrin superfamily. London: Academic Press, 1994.

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Hartwig, John H. Actin-binding proteins 1: Spectrin superfamily. London: Academic Press, 1994.

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Hartwig, John H. Actin-binding proteins 1: spectrin superfamily. London: Academic Press, 1995.

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Vann, Bennett, ed. Membrane skeletons and cytoskeletal-membrane associations: Proceedings of a UCLA Symposium held in Park City, Utah, March 9-15, 1985. New York: Liss, 1986.

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Tomasi, Richard A. A spectrum of spectral problems. Tulsa, Oklahoma: Sunbelt R & T, Inc. [distributor], 1994.

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Tomasi, Richard A. A spectrum of spectral problems. Tulsa, Oklahoma: Sunbelt R & T, Inc., 1994.

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International, Conference on Spectral Line Shapes (14th 1998 State College Pennsylvania). Spectral line shapes. Woodbury, New York: American Institute of Physics, 1999.

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O, Silʹd, and Khaller K. E, eds. Besfononnye linii v spektroskopii i fotokhimii. Tartu: Akademii͡a︡ nauk Ėstonskoĭ SSR, 1986.

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H, Tipping R., and United States. National Aeronautics and Space Administration., eds. An improved quasistatic line-shape theory: The effect of molecular motion on the line wings. [Washington, D.C: National Aeronautics and Space Administration, 1994.

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Colombo, Fabrizio, Jonathan Gantner, and David P. Kimsey. Spectral Theory on the S-Spectrum for Quaternionic Operators. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-030-03074-2.

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Części książek na temat "Spectrin"

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Czogalla, Aleksander. "Spectrin." In Encyclopedia of Signaling Molecules, 5106–12. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_101871.

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Czogalla, Aleksander. "Spectrin." In Encyclopedia of Signaling Molecules, 1–7. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4614-6438-9_101871-1.

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Ralston, Greg B. "Spectrin-Actin Interactions." In Blood Cell Biochemistry, 227–50. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4757-9528-8_8.

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Branton, D. "Spectrin Interchain Binding in Drosophila Development." In The Cytoskeleton, 61–70. Berlin, Heidelberg: Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-642-79482-7_7.

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Lutz, Hans U., Dieter Maretzki, and Mariagabriella Mariani. "A cAmp-Dependent Phosphorylation Alters Spectrin Binding Properties." In Springer Series in Biophysics, 328–36. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-73925-5_59.

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Elgsaeter, Arnljot, Arne Mikkelsen, and Bjørn T. Stokke. "Spectrin and the Mechanochemical Properties of the Erythrocyte Membrane." In The Cytoskeleton, 187–97. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2161-3_14.

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Sarkar, Sauvik, Dipayan Bose, Rajendra P. Giri, Mrinmay K. Mukhopadhyay, and Abhijit Chakrabarti. "Status of Membrane Asymmetry in Erythrocytes: Role of Spectrin." In Advances in Experimental Medicine and Biology, 3–11. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-3065-0_1.

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Delalande, Olivier, Aleksander Czogalla, Jean-François Hubert, Aleksander Sikorski, and Elisabeth Le Rumeur. "Dystrophin and Spectrin, Two Highly Dissimilar Sisters of the Same Family." In Subcellular Biochemistry, 373–403. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-49674-0_12.

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Kramer, G., W. Kudlicki, S. Fullilove, and B. Hardesty. "Association of the Heme-Controlled eIF-2α Kinase with Spectrin-Derived Peptides." In Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, 265–67. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-72624-8_56.

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Bennett, V., J. Steiner, J. Davis, H. Kaiser, and E. Kordeli. "Strategies in Regulation of Protein Associations of the Spectrin-Based Membrane Skeleton." In Springer Series in Biophysics, 319–27. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-73925-5_58.

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Streszczenia konferencji na temat "Spectrin"

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Mishra, Kamini, Abhijit Chakrabarty, and Puspendu K. Das. "Spectrin-hemoglobin interaction studied by second harmonic light scattering." In International Conference on Fibre Optics and Photonics. Washington, D.C.: OSA, 2016. http://dx.doi.org/10.1364/photonics.2016.tu4a.73.

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Parry, David A. D., та Carolyn Cohen. "Structure of the spectrin superfamily: A three-α-helix motif". У The living cell in four dimensions. AIP, 1991. http://dx.doi.org/10.1063/1.40604.

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Lykotrafitis, George, and He Li. "Two-Component Coarse-Grain Model for Erythrocyte Membrane." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-62133.

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Biological membranes are vital components of living cells as they function to maintain the structural integrity of the cells. Red blood cell (RBC) membrane comprises the lipid bilayer and the cytoskeleton network. The lipid bilayer consists of phospholipids, integral membrane proteins, peripheral proteins and cholesterol. It behaves as a 2D fluid. The cytoskeleton is a network of spectrin tetramers linked at the actin junctions. It is connected to the lipid bilayer primarily via Band-3 and ankyrin proteins. In this paper, we introduce a coarse-grained model with high computational efficiency f
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Zhang, Pan, Utz Herbig, and Muriel W. Lambert. "Abstract 2121: Nonerythroid alpha spectrin prevents telomere fragility after DNA interstrand crosslink damage." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-2121.

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Barry, Christina F., Songwei Wu, Donna L. Cioffi, and Troy Stevens. "Disruption Of The Constitutive Spectrin-actin Interaction Induces Inter-endothelial Cell Gap Formation." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3428.

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Armiger, T. J., and K. N. Dahl. "The role of αII-spectrin in mechanics and compressive resilience of the cell nucleus." In 2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC). IEEE, 2015. http://dx.doi.org/10.1109/nebec.2015.7117147.

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Zhi, Xiuling, Ling Lin, Narayan Shivapurkar Shivapurkar, John L. Marshall, Lynt Johnson та Aiwu R. He. "Abstract 5275: βII-spectrin(SPTBN1) suppresses tumor progression by inhibiting Wnt signaling via kallistatin in hepatocellular carcinoma". У Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-5275.

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Sulstarova, S., A. Foley, S. Mylvaganam, B. E. Steinberg, S. A. Freeman, and N. M. Goldenberg. "Breakdown of the Apical Spectrin Network Leads to Endothelial Dysfunction and Vascular Stiffening in Pulmonary Arterial Hypertension." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1019.

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Yang, Shaoxian, Majed El Zouhairi, Sang S. Kim, Lopa Mishra, and Michael J. Pishvaian. "Abstract 3884: Beta-2 spectrin opposes the CDK4-mediated suppression of TGF-beta signaling by rescuing Smad3 nuclear localization." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3884.

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Lin, Ling, Hua Wang, Bin Gao, Xiuling Zhi та Aiwu Ruth He. "Abstract 5184: Mechanistic analysis of liver inflammation and cancer formation in mice with heterozygous lose of β-spectrin (β2SP)." У Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-5184.

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Raporty organizacyjne na temat "Spectrin"

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Shen, B. W., F. J. Stevens, U. Luthi, and S. B. Goldin. Structural basis of spectrin elasticity. Office of Scientific and Technical Information (OSTI), October 1991. http://dx.doi.org/10.2172/10148966.

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De Camilli, Pietro. Beta IV Spectrin in Normal and Cancer Breast Cells. Fort Belvoir, VA: Defense Technical Information Center, September 2002. http://dx.doi.org/10.21236/ada418127.

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Kotula, Leszek, Jiliu Xu, Jill A. Macoska, Piotr Kozlowski, and Magdalena Martinka. The Role of Human Spectrin SH3 Domain Binding Protein 1 (HSSH3BPl) in Prostatic Adenocarcinoma. Fort Belvoir, VA: Defense Technical Information Center, September 2004. http://dx.doi.org/10.21236/ada430579.

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Kotula, Leszek, Jiliu XU, Jill A. Macoska, Piotr Kozlowski, and Magdalena Martinka. The Role of Human Spectrin SH3 Domain Binding Protein 1 (HSSH3BP1) in Prostatic Adenocarcinoma. Fort Belvoir, VA: Defense Technical Information Center, September 2002. http://dx.doi.org/10.21236/ada411959.

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Kotula, Leszek, Jiliu Xu, Jill A. Macoska, Piotr Kozlowski, Magdalena Martinka, and Edward C. Jones. The Role of Human Spectrin SH3 Domain Binding Protein 1 (HSSH3BP1) in Prostatic Adenocarcinoma. Fort Belvoir, VA: Defense Technical Information Center, September 2003. http://dx.doi.org/10.21236/ada419543.

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Simakov, S. Evaluation of the Prompt Gamma-ray Spectrum from Spontaneous Fission of 252Cf. IAEA Nuclear Data Section, February 2024. http://dx.doi.org/10.61092/iaea.bz1p-e3yc.

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The energy spectra, multiplicities and average energies of the prompt, total and delayed γ-rays accompanying the spontaneous fission of 252Cf were collected from the literature and dedicated databases. They were carefully analysed for consistency with a view to producing reference data for usage in various applications. This could be accomplished for the prompt fission gamma ray spectrum up to 20 MeV since dozens of measurements exist and reasonably agree. The prompt fission gamma ray spectrum (PFGS) was non-model evaluated by fitting the preselected experimental data with the help of the gene
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Lee, Amy Sarah. Determination of the Spectral Index in the Fission Spectrum Energy Regime. Office of Scientific and Technical Information (OSTI), May 2016. http://dx.doi.org/10.2172/1253539.

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Alchanatis, Victor, Stephen W. Searcy, Moshe Meron, W. Lee, G. Y. Li, and A. Ben Porath. Prediction of Nitrogen Stress Using Reflectance Techniques. United States Department of Agriculture, November 2001. http://dx.doi.org/10.32747/2001.7580664.bard.

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Commercial agriculture has come under increasing pressure to reduce nitrogen fertilizer inputs in order to minimize potential nonpoint source pollution of ground and surface waters. This has resulted in increased interest in site specific fertilizer management. One way to solve pollution problems would be to determine crop nutrient needs in real time, using remote detection, and regulating fertilizer dispensed by an applicator. By detecting actual plant needs, only the additional nitrogen necessary to optimize production would be supplied. This research aimed to develop techniques for real tim
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Corriveau, Elizabeth, Travis Thornell, Mine Ucak-Astarlioglu, Dane Wedgeworth, Hayden Hanna, Robert Jones, Alison Thurston, and Robyn Barbato. Characterization of pigmented microbial isolates for use in material applications. Engineer Research and Development Center (U.S.), March 2023. http://dx.doi.org/10.21079/11681/46633.

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Organisms (i.e., plants and microorganisms) contain pigments that allow them to adapt and thrive under stressful conditions, such as elevated ultraviolet radiation. The pigments elicit characteristic spectral responses when measured by active and passive sensors. This research study focused on characterizing the spectral response of three organisms and how they compared to background spectral signatures of a complex environment. Specifically, spectra were collected from a fungus, a plant, and two pigmented bacteria, one of which is an extremophile bacterium. The samples were measured using Fou
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Wilson, R. D. Spectrum shape-analysis techniques applied to the Hanford Tank Farms spectral gamma logs. Office of Scientific and Technical Information (OSTI), May 1997. http://dx.doi.org/10.2172/501524.

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