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Artykuły w czasopismach na temat "Steinbeck Research Center"

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Lekan, Thomas M. "“A Delicate Equilibrium of the Most Complex Sort”." Historical Studies in the Natural Sciences 53, no. 2 (2023): 147–88. http://dx.doi.org/10.1525/hsns.2023.53.2.147.

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This article examines the intertidal ecological research of the commercial lab owner and popular science writer Edward F. Ricketts, best known as the prototype for John Steinbeck’s character “Doc” in the novel Cannery Row (1945). Ricketts’s friendship with Steinbeck and unconventional philosophical style have regrettably overshadowed his scientific work, particularly his novel faunal zonation surveys of the North American Pacific littoral in the 1930s and 1940s. These surveys resulted in a landmark handbook, Between Pacific Tides (1939), designed for novices and specialists alike. Ricketts’s w
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Huber, T., and H. Emmerich. "Innovatives Reinigungsverfahren für oberflächenempfindliche Bauteile/Innovative cleaning method for surface-sensitive components based on robot-supported, process-oriented single component cleaning in machining manufacturing processes." wt Werkstattstechnik online 109, no. 09 (2019): 684–87. http://dx.doi.org/10.37544/1436-4980-2019-09-70.

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Im Rahmen eines vom BMBF (Bundesministerium für Bildung und Forschung) geförderten Projektes erforschte die Firma Optik-Elektro Huber GmbH in Zusammenarbeit mit dem Steinbeis-Transferzentrum für Produktion und Organisation ein neuartiges Reinigungsverfahren von komplexen, oberflächenempfindlichen Bauteilen. Im Fokus des Beitrags steht der Aufbau und die Wirkungsweise des Systems, welches auf der Einzelteilhandhabung der einzelnen Werkstücke in direkter Kopplung mit dem Fertigungsprozess beruht.   As part of a project, funded by the Federal Ministry of Education and Research (BMBF), th
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Shvydenko, O. "ADAPTATION “INSTITUTE OF RADIO ELECTRONICS” BUILDING IN KHARKIV FOR MODERN USING." Problems of theory and history of architecture of Ukraine, no. 20 (May 12, 2020): 131–40. http://dx.doi.org/10.31650/2519-4208-2020-20-131-140.

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Adaptation to modern requirements of buildings, which have got a status of architectural landmarks, is always a compromise between the preservation of authentic elements and bringing the building into line with current standards. In the Building of the Institute of Radio Electronics, the architectural landmark of Kharkiv region, it was necessary to build an elevator to provide barrier-free access to the premises.The goal of this research is to find the best place for a new elevator, where meddling into the building’s body from one side will make minimum damage for its structure and interior de
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Yuan, Charlotte, Erina Quinn, Sargam Kapoor, et al. "Hypoxia Enhanced Red Cell Adhesion in Vitro May Identify Patients at Risk for Vasculopathy." Blood 132, Supplement 1 (2018): 3672. http://dx.doi.org/10.1182/blood-2018-99-120207.

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Abstract Background: Priapism is a serious complication associated with Sickle Cell Disease (SCD) that may be a manifestation of underlying vasculopathy. The Centers for the Study of Complex Diseases of Childhood (CSCCD), comprising independent Comprehensive Sickle Cell Centers, demonstrated an association of priapism with hemolysis.1 Previously, we identified two groups of people with SCD based on red blood cell (RBC) adhesion under hypoxic conditions: those patients whose RBCs showed hypoxia-enhanced adhesion (HEA) and those whose did not (non-HEA).2 Patients with HEA had evidence for more h
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Skorupan, Nebojsa, Mehwish I. Ahmad, Seth M. Steinberg, et al. "Abstract PO-054: A phase II trial of the super-enhancer inhibitor Minnelide in advanced refractory adenosquamous carcinoma of the pancreas (ASCP)." Cancer Research 81, no. 22_Supplement (2021): PO—054—PO—054. http://dx.doi.org/10.1158/1538-7445.panca21-po-054.

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Abstract Background: Adenosquamous carcinoma of the pancreas (ASCP) is a very rare and highly aggressive variant of pancreatic ductal adenocarcinoma (PDA), accounting for 0.5-4% of all pancreatic cancer cases in the US. Current data indicates that epigenetic changes and Myc overexpression lead to squamous transdifferentiation of pancreatic tumor cells and development of ASCP. Minnelide is an oral anti-super-enhancer drug that inhibits Myc expression in preclinical models of ASCP. Oral Minnelide has been previously tested in the clinic where a Phase I study determined a recommended phase 2 dose
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Takahashi, Nobuyuki, Zhonglin Hao, Liza C. Villaruz, et al. "Abstract LB_A10: Efficacy of ATR inhibitor berzosertib plus topotecan or topotecan alone in patients with relapsed small cell lung cancer: A randomized clinical trial." Molecular Cancer Therapeutics 22, no. 12_Supplement (2023): LB_A10. http://dx.doi.org/10.1158/1535-7163.targ-23-lb_a10.

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Abstract Background: Patients with relapsed small cell lung cancer (SCLC) have a poor prognosis and few therapeutic options, especially after standard treatment of platinum doublet chemotherapy +/- immunotherapy. SCLC is characterized with high replication stress. A previous single-arm phase 2 study showed anti-tumor activity with the addition of ataxia-telangiectasia–mutated and rad3-related (ATR) kinase inhibitor berzosertib to topotecan. This study aimed to investigate whether the addition of berzosertib to topotecan improves clinical outcomes in patients with relapsed SCLC. Patients and me
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Itzep, Nelda, Siddharth Jadhav, Celeste K. Kanne, and Vivien A. Sheehan. "Spontaneous Healing of Avascular Necrosis of the Femoral Head in Sickle Cell Disease." Blood 132, Supplement 1 (2018): 4924. http://dx.doi.org/10.1182/blood-2018-99-119328.

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Abstract Background. Avascular necrosis (AVN) is a serious complication of sickle cell disease (SCD) that can lead to significant morbidity including chronic pain and physical impairment with treatment depending on the patient's pain severity and functional limitation. Patient age, hemoglobin levels, and abnormal rheology, particularly high blood viscosity, or thickness, and percentage of dense red blood cells, defined as cells >1.11 mg/mL have been identified as risk factors for the development of AVN, but their contributions to the subsequent clinical course has not been described. The na
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Han, Jin, Santosh L. Saraf, Michel Gowhari, et al. "Impact of Intravenous Opioid Shortage on Managing Pain Crisis in Sickle Cell Disease." Blood 134, Supplement_1 (2019): 3390. http://dx.doi.org/10.1182/blood-2019-122249.

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Background: Vaso-occlusive crisis (VOC) is the hallmark complication of sickle cell disease (SCD) (1), and usually requires intravenous (IV) opioid treatment in emergency room (ER) or acute care center (ACC), a designated observation unit to manage uncomplicated VOC (2). Starting October 2017, there was a critical nationwide drug shortage in parental hydromorphone, a commonly used medication to treat VOC. In April 2018 the University of Illinois Health System (UI Health) adopted a standardized pain management protocol that limited opioids in the ER or ACC to two doses of IV or IM morphine and/
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Galactéros, Frédéric, Ersi Voskaridou, Anoosha Habibi, et al. "Sickle-Cell Disease Patients' Attitudes Towards Their Treatment with Hydroxycarbamide." Blood 134, Supplement_1 (2019): 1013. http://dx.doi.org/10.1182/blood-2019-125673.

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Hydroxyurea (HU) is approved in the EU and USA for prevention of vaso-occlusive crises (VOC) including acute chest syndromes (ACS) in patients over 2 years with sickle-cell disease (SCD). The major benefits of HU in SCD are directly related to its abilities to increase HbF, decrease sickling of red blood cells and hemolysis, leading to reduction of vaso-occlusive episodes, need for blood transfusions and consequently reduction of morbidity and mortality. Adherence to the treatment is paramount for effectiveness, but in spite of proven benefits, barriers to adherence persist.[1] ESCORT-HU study
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Voskaridou, Ersi, Lena Oevermann, Corinne Armari-Alla, et al. "Sustainability of Hematological and Clinical Benefits to HU Administration in the Prevention of Sickle-Cell Vaso-Occlusive Crises in Routine Practice." Blood 132, Supplement 1 (2018): 855. http://dx.doi.org/10.1182/blood-2018-99-116040.

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Abstract Hydroxyurea (HU) is approved in EU and USA for preventing vaso-occlusive crises (VOC) including acute chest syndromes (ACS) in adults, adolescents and children ≥2 years with sickle-cell disease (SCD). Further to the double blinded, randomized controlled Multicenter Study of Hydroxyurea administration (MSH) which provided the first data on clinical efficacy of HU (Charache 1995), a few follow-up studies suggested that long-term use of HU resulted in significant clinical benefit on patient outcome. This was reflected by lower mortality rates in HU-treated patients compared to convention
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Książki na temat "Steinbeck Research Center"

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Center, Steinbeck Research. The Steinbeck Research Center at San Jose State University: A descriptive catalogue. The University, 1985.

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Johnson, Claudia Durst. Understanding Of Mice and Men, The Red Pony and The Pearl. Greenwood, 1997. http://dx.doi.org/10.5040/9798216029656.

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Although John Steinbeck's novellasOf Mice and Men,The Red Pony, andThe Pearlare works of fiction, they provide a window on the history of the times and places they portray. Studying the historical, social, economic, and regional background of each novella is important to fully understanding each work. This interdisciplinary collection of rich collateral materials features a variety of primary documents that shed light on the background of each of these novellas—the pioneer days and life on the Western frontier, the early history of California, the gold rush, the plight of the migrant worker du
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Booker, M. Keith, ed. Literature and Politics Today. ABC-CLIO, LLC, 2015. http://dx.doi.org/10.5040/9798400680076.

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Focusing on the intersection of literature and politics since the beginning of the 20th century, this book examines authors, historical figures, major literary and political works, national literatures, and literary movements to reveal the intrinsic links between literature and history. Literary works have often engaged political issues, and many political writings give close attention to literary concerns. This encyclopedia explores the complex relationship between literature and politics through detailed entries written by expert contributors on authors, historical figures, major literary an
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Johnson, Claudia Durst. Understanding The Grapes of Wrath. Greenwood, 1999. http://dx.doi.org/10.5040/9798216029885.

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WhenThe Grapes of Wrathwas published in 1939, it had an explosive effect on the public, calling attention to the problems of migrant farm workers during the Great Depression. This casebook provides a rich source of primary materials on the period and the plight of the migrant farm worker that brings to life the problems Steinbeck immortalized in the novel. Included are interviews with eyewitnesses to the Dust Bowl, firsthand accounts and investigative reports of the causes and effects of the Great Depression, letters to Eleanor Roosevelt and Labor Secretary Frances Perkins, diaries and autobio
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Hank, Karsten, Frank Schulz-Nieswandt, Michael Wagner, and Susanne Zank, eds. Alternsforschung. Nomos Verlagsgesellschaft mbH & Co. KG, 2019. http://dx.doi.org/10.5771/9783845276687.

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This handbook aims to provide an overview of knowledge about age and ageing in ‘Western’ societies at the beginning of the 21st century, which is intended to be equally suitable for research and practice. It focuses on relevant contributions from the social and behavioural sciences and their access to selected aspects of age and ageing. Its main topics can be described as quintessential core subjects, e.g. theories of ageing, socio-economic situation and inequalities, mental and physical health, social networks and social participation. These are supplemented by contributions on often marginal
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Części książek na temat "Steinbeck Research Center"

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Paranhos, Kátia Rodrigues. "Companhia Teatro Moderno de Lisboa (TML): engagement, resistance and cultural creation in the 1960s." In DEVELOPMENT AND ITS APPLICATIONS IN SCIENTIFIC KNOWLEDGE. Seven Editora, 2023. http://dx.doi.org/10.56238/devopinterscie-081.

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Social theatre and politically engaged theatre are two designations that gained acceptance amid a lively debate that went on throughout the late 19th century and consolidated in the 20th century. Its turning point lay in the structure of the relations between theatre and politics or even between theatre and propaganda. This text addresses what resistance and political-cultural protest meant to Grupo Teatro Moderno de Lisboa (TML), from Lisbon/Portugal, in the 1960s, based on the interviews and discourses about their collective creation processes, theoretical research, and social intervention. According to many interpreters, the Group broke with the theater establishment of 1960 and came out as one generation's great movement. It only lasted for 4 years, from 1961 to 1965. During this time, TML staged theatrical texts by Carlos Muniz, Dostoyevsky, Miguel Mihura, John Steinbeck, Luiz Francisco Rebello, William Shakespeare, and José Carlos Pires. These artists made up and remade different universes according to their purposes and wishes. By reading the above authors' texts in the 1960s, these Portuguese artists gave new meanings to the present and to the past itself – recalling here Brecht's "past and present in one". The political and aesthetic issues in the plays were updated through debates between the theater group and the audience —quite a difficult task in a period when a political-cultural protest against the "Estado Novo" dictatorship was increasingly strong and constant, and in which official censorship, always vigilant against heterodox artistic manifestations, was stifling. Being active in the politically engaged theater then meant looking for different staging places and other points of view on the years of lead. Utilizing its actions, it is a ground principle, and its practices, TML would sow the seeds of the independent theatre group movement, having taken the first steps in the pathway toward an intervention theater that, later on, these groups took upon themselves to continue with. Despite adversities, theatrical experiments that go against the grain of prevailing thoughts are still tenaciously current on the agenda. Doing theater amid commercial pressure is, undoubtedly, a form of provocation, of insubordination to the "hit parade" market, to which Comuna – Teatro Pesquisa, Teatro da Cornucópia, O Bando, Casa da Comédia, A Barraca, the Évora Culture Center and SeivaTrupestill resort.
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Davis, King. "The Intersection of Fee-for-Service, Managed Health Care, and Cultural Competence." In Managed Care Services. Oxford University PressNew York, NY, 2000. http://dx.doi.org/10.1093/oso/9780195134292.003.0004.

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Abstract Throughout the twentieth century, a large number of studies and authors have confirmed that access, quality of care, and years of healthy living showed a significant relationship to race, ethnicity, income, and social class under the traditional fee-for-service system prevalent in the United States (Abe-Kim & Takeuchi, 1996; Ayanian, 1994; Center for Health Economics Research, 1993; Clinton, 1998; Cole & Pilisuk, 1976; Council on Ethical and Judicial Affairs, 1989; Garretson, 1993; Gaston, Barrett et al., 1998; Hadley, Steinberg et al., 1991; Hawkins & Rosenbaum, 1993; Jang, Lee et al., 1998; Jones & Gray, 1986; Livingston, 1994; Moy & Bartman, 1995; Mutchler & Burr, 1991; McWhorter & Moyer, 1987; Rice & Winn, 1990; Peterson, Wright et al., 1994; Weiss, 1997). These articles and studies show that under the American fee-for-service system the health and mental health problems of low-income people of color were misdiagnosed frequently, diagnosed more severely than the symptoms warranted, but treated less frequently with current medical procedures than were whites, even when there were no differences in ability to pay for services (Mutchler & Burr, 1991; Peterson, Wright et al., 1994).
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